A pharmaceutical powder uniform mixing device

By designing a uniform mixing device for pharmaceutical powders with rotary drive and hot air conveying mechanism, the problem of the raw drug powders prone to agglomeration in the mixing device is solved, achieving efficient and uniform mixing and improving the consistency of tablet product quality.

CN222724139UActive Publication Date: 2025-04-08GUANGDONG JIUMING PHARMA
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Patent Information

Application Number
CN202421248742.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-03
Publication Date
2025-04-08
Estimated Expiration
2034-06-03

AI Technical Summary

Technical Problem

In the prior art, the raw material powder is prone to local clumping or accumulation in the mixing device, resulting in uneven mixing and low mixing efficiency, which affects the quality and consistency of the tablet product.

Method used

A uniform mixing device for pharmaceutical powders is designed, using a rotary driving mechanism to drive the mixing barrel to rotate, combined with a hot air conveying mechanism to reduce the humidity of the raw material powder, and guide the diversion of the raw material powders through an arc-shaped shunt to ensure uniform distribution.

Benefits of technology

It achieves good fluidity and efficient mixing of raw material powders, avoids clumping, and improves mixing efficiency and the consistency of the quality of the tablet product.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a uniform powder mixing device for pharmaceutical use, including a machine base, a mixing barrel, a rotary support assembly, a rotary drive mechanism, a feed hopper, a hot air conveying mechanism and a screening drop hopper; the hot air conveying mechanism is arranged at one end of the mixing barrel, and the mixing barrel is provided with a plurality of arc-shaped diverter sheets arranged at intervals along the inner wall, and a diverter channel for the flow of raw material medicine powder is formed between two adjacent arc-shaped diverter sheets. When the utility model mixes the raw material medicine powder, the hot air conveying mechanism can generate hot air and airflow and convey it into the mixing barrel to reduce the humidity in the raw material medicine powder, avoid local agglomeration affecting the mixing effect, improve the fluidity of the raw material medicine powder, make the raw material medicine powder easier to be stirred and mixed, and improve the mixing efficiency; the setting of the arc-shaped diverter sheet can guide the raw material medicine powder to be diverted in the mixing barrel to ensure that the raw material medicine powder is evenly distributed during the mixing process and promote the mixing effect.
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Description

Technical Field

[0001] The utility model relates to the field of mixing devices, in particular to a uniform powder mixing device for pharmaceutical use. Background Art

[0002] In the pharmaceutical manufacturing field, when APIs are produced in large quantities, they are produced in batches. Different batches of APIs, even if the reaction conditions are exactly the same, will have slight differences in components in different reaction chambers. In order to ensure the production quality of tablets, different batches of APIs are usually mixed using a mixing cylinder so that the content of the preparations can be more uniform during subsequent preparation production to ensure the quality of the tablets.

[0003] In the prior art, since the API powder has a certain humidity, when the mixing device is mixing the API powder, the API powder is prone to local agglomeration or accumulation in the mixing barrel, resulting in uneven mixing and reduced mixing efficiency, thereby affecting the product quality and consistency of subsequent preparation tablets.

[0004] Therefore, the prior art has defects and needs to be improved. Utility Model Content

[0005] The technical problem to be solved by the utility model is to provide a pharmaceutical powder uniform mixing device which has good flow effect, high mixing efficiency and can avoid the agglomeration of raw material medicine powder.

[0006] To achieve this purpose, the utility model adopts the following technical scheme: a pharmaceutical powder uniform mixing device, including a machine base, a mixing barrel, a rotary support assembly, a rotary drive mechanism, a feed hopper, a hot air conveying mechanism and a screening drop hopper;

[0007] The bottom of the mixing drum is connected to the machine base through the rotary support assembly, and the rotary drive mechanism is in transmission connection with the mixing drum to drive the mixing drum to rotate on the rotary support assembly;

[0008] The feed hopper is connected to the top of the mixing barrel, and is used to convey the raw material drug powder into the mixing barrel. The hot air conveying mechanism is provided at one end of the mixing barrel, and is used to convey the hot air flow toward the mixing barrel. The screening hopper is provided at the other end of the mixing barrel, and is used to screen the raw material drug powder after mixing.

[0009] The mixing barrel is provided with a plurality of arc-shaped flow-dividing pieces arranged at intervals along the inner wall, and a flow-dividing channel for the raw material drug powder to flow is formed between two adjacent arc-shaped flow-dividing pieces. The arc-shaped flow-dividing pieces are used to divert the raw material drug powder in the mixing barrel.

[0010] According to the above technical solution, in the pharmaceutical powder uniform mixing device, the rotary drive mechanism includes a drive motor, a pulley transmission assembly, a rotating shaft, a drive gear and an endless chain;

[0011] The annular chain is sleeved on the circumferential outer wall of the mixing barrel, the rotating shaft is mounted on the machine base through a bearing seat, and the rotating shaft is arranged parallel to the mixing barrel, the driving gear is arranged on the rotating shaft and meshed with the annular chain, and the output shaft of the driving motor is connected to the rotating shaft through the pulley transmission assembly to drive the rotating shaft to rotate.

[0012] By adopting the above-mentioned technical solutions, in the pharmaceutical powder uniform mixing device, the rotary support assembly includes a rubber ring and a pulley;

[0013] The two rubber sleeves are respectively arranged on the mixing barrel at both sides of the annular chain, the pulley is arranged on the machine base below the rubber sleeve, and the pulley is provided with a receiving slide groove for abutting against the rubber sleeve.

[0014] By adopting the above-mentioned technical solutions, in the pharmaceutical powder uniform mixing device, the hot air conveying mechanism includes an air supply bin, a heating pipe and a fan;

[0015] The air supply bin is communicated with the mixing barrel, the heating pipe is arranged in the air supply bin, the fan is arranged on a side of the air supply bin away from the mixing barrel, and the fan is used to blow the heat generated by the heating pipe into the mixing barrel.

[0016] By adopting the above-mentioned technical solutions, in the pharmaceutical powder uniform mixing device, the screening hopper includes a screening bin, a first feeding pipe, a second feeding pipe and an annular screen;

[0017] The screening bin is arranged at the discharge end of the mixing barrel, the first drop pipe and the second drop pipe are arranged in the screening bin, the annular screen is arranged above the first drop pipe, and the annular screen is abutted against the end of the mixing barrel, and the first drop pipe is used to receive the raw material powder screened by the annular screen.

[0018] By adopting the above-mentioned technical solutions, in the pharmaceutical powder uniform mixing device, the mixing barrel is tiltedly arranged on the machine base, and the height of the mixing barrel gradually decreases from the hot air conveying mechanism to the screening hopper.

[0019] By adopting the above-mentioned technical solutions, in the pharmaceutical powder uniform mixing device, an arc-shaped material guide groove is provided at the bottom of the feed hopper, the material bearing surface of the arc-shaped material guide groove is away from the air supply bin, and the arc-shaped material guide groove is used to guide and transport the raw material powder into the mixing barrel.

[0020] By adopting the above-mentioned technical solutions, in the pharmaceutical powder uniform mixing device, a receiving bucket is provided at the bottom of the second drop pipe, and the receiving bucket is used to receive the raw material powder that has not been screened by the annular screen.

[0021] Compared with the prior art, the utility model has the following beneficial effects:

[0022] The feeding hopper of the utility model can convey different batches of raw material medicine powders to be mixed into the mixing barrel, and then the rotary driving mechanism drives the mixing barrel to rotate, so that the raw material medicine powders in the mixing barrel are continuously rolled, turned over and rotated, thereby achieving the mixing of the raw material medicine powders; during the mixing process, the hot air conveying mechanism can generate hot air and airflow and convey it to the mixing barrel. Such a setting can reduce the humidity in the raw material medicine powders, avoid local agglomeration affecting the mixing effect, improve the fluidity of the raw material medicine powders, make the raw material medicine powders easier to be stirred and mixed, and improve the mixing efficiency; the setting of the arc-shaped diverter plate can guide the raw material medicine powders to be diverted in the mixing barrel, so as to ensure that the raw material medicine powders are evenly distributed during the mixing process and promote the mixing effect; when the raw material medicine powders are mixed, the screening hopper can screen the particle size of the raw material medicine powders to remove the agglomerated parts, so as to ensure that the raw material medicine powders discharged meet the quality requirements. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0024] The structures, proportions, sizes, etc. illustrated in the drawings of this specification are only used to match the contents disclosed in the specification so as to facilitate understanding and reading by persons familiar with this technology. They are not used to limit the conditions under which the present invention can be implemented, and therefore have no substantive technical significance. Any structural modification, change in proportion or adjustment of size, without affecting the effects and purposes that can be achieved by the present invention, should still fall within the scope of the technical contents disclosed by the present invention.

[0025] Figure 1 It is a schematic diagram of the overall structure of the utility model;

[0026] Figure 2 This is a schematic diagram of the internal structure of the mixing cylinder of the utility model;

[0027] Figure 3 This is a schematic diagram of the hot air conveying mechanism structure of the utility model;

[0028] Figure 4 It is a schematic diagram of the internal structure of the screening hopper of the utility model. DETAILED DESCRIPTION

[0029] In order to make the utility model's purpose, features, and advantages more obvious and easy to understand, the following will be combined with the drawings in the utility model embodiments to clearly and completely describe the technical solutions in the utility model embodiments. Obviously, the embodiments described below are only part of the utility model embodiments, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0030] In the description of the present invention, it should be understood that the terms "upper", "lower", "top", "bottom", "inside", "outside", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention. It should be noted that when a component is considered to be "connected" to another component, it may be directly connected to the other component or there may be a centrally arranged component at the same time.

[0031] The technical solution of the utility model is further explained below with reference to the accompanying drawings and through specific implementation methods.

[0032] like Figures 1 to 4As shown, the embodiment of the utility model provides a pharmaceutical powder uniform mixing device, including a machine base 1, a mixing barrel 2, a rotary support assembly 3, a rotary drive mechanism 4, a feed hopper 5, a hot air conveying mechanism 6 and a screening drop hopper 7. The bottom of the mixing barrel 2 is connected to the machine base 1 through the rotary support assembly 3, and the rotary drive mechanism 4 is transmission-connected to the mixing barrel 2 to drive the mixing barrel 2 to rotate on the rotary support assembly 3; the feed hopper 5 is connected to the top of the mixing barrel 2, and the feed hopper 5 is used to convey the raw material powder to the mixing barrel 2. In the barrel 2, the hot air conveying mechanism 6 is arranged at one end of the mixing barrel 2, and the hot air conveying mechanism 6 is used to convey a hot air flow toward the mixing barrel 2. The screening hopper 7 is arranged at the other end of the mixing barrel 2, and the screening hopper 7 is used to screen the raw material powder that has been mixed. The mixing barrel 2 is provided with a plurality of arc-shaped diverter pieces 21 arranged at intervals along the inner wall, and a diverter channel 22 for the raw material powder to flow is formed between two adjacent arc-shaped diverter pieces 21, and the arc-shaped diverter pieces 21 are used to divert the raw material powder in the mixing barrel 2. The feeding hopper 5 can convey different batches of raw material powders to be mixed into the mixing barrel 2, and then the rotary driving mechanism 4 drives the mixing barrel 2 to rotate, so that the raw material powders in the mixing barrel 2 are continuously rolled, turned and rotated, thereby achieving the mixing of the raw material powders; during the mixing process, the hot air conveying mechanism 6 can generate hot air and airflow and convey it to the mixing barrel 2. Such a setting can reduce the humidity in the raw material powders, avoid local agglomeration affecting the mixing effect, improve the fluidity of the raw material powders, make the raw material powders easier to be stirred and mixed, and improve the mixing efficiency; the setting of the arc-shaped diverter plate 21 can guide the raw material powders to be diverted in the mixing barrel 2, so as to ensure that the raw material powders are evenly distributed during the mixing process and promote the mixing effect; when the raw material powders are mixed, the screening hopper 7 can screen the raw material powders for particle size to remove the agglomerated parts and ensure that the raw material powders discharged meet the particle size requirements.

[0033] like Figure 1As shown, further, the rotary drive mechanism 4 includes a driving motor 41, a pulley transmission assembly 42, a rotating shaft 43, a driving gear 44 and an annular chain 45, wherein the annular chain 45 is sleeved on the circumferential outer wall of the mixing barrel 2, the rotating shaft 43 is mounted on the machine base 1 through a bearing seat, and the rotating shaft 43 is arranged parallel to the mixing barrel 2, the driving gear 44 is arranged on the rotating shaft 43, and is meshed and connected with the annular chain 45, and the output shaft of the driving motor 41 is connected to the rotating shaft 43 through the pulley transmission assembly 42, so as to drive the rotating shaft 43 to rotate. When the driving motor 41 is running, the rotating shaft 43 can be driven to rotate through the pulley transmission assembly 42, and then the annular chain 45 meshed and connected with the driving gear 44 can be driven to rotate, thereby realizing the rotation of the mixing barrel 2, so that the raw material drug powder can continuously roll, flip and rotate in the mixing barrel 2, thereby achieving the purpose of mixing.

[0034] like Figure 1 As shown, further, the rotary support assembly 3 includes a rubber sleeve 31 and a pulley 32, the two rubber sleeves 31 are respectively arranged on the mixing barrel 2 on both sides of the ring chain 45, the pulley 32 is arranged on the machine base 1 below the rubber sleeve 31, and the pulley 32 is provided with a receiving slide 320 for abutting against the rubber sleeve 31. The pulley 32 can rotatably support the rubber sleeve 31, and the setting of the receiving slide 320 can prevent the rubber sleeve 31 from slipping off the pulley 32; in addition, the rubber sleeve 31 can also play a role in shock absorption and buffering, effectively extending the service life of the equipment.

[0035] like Figure 1 and Figure 3 As shown, further, the hot air conveying mechanism 6 includes an air supply bin 61, a heating pipe 62 and a fan 63. The air supply bin 61 is connected to the mixing barrel 2. The heating pipe 62 is arranged in the air supply bin 61. The fan 63 is arranged on the side of the air supply bin 61 away from the mixing barrel 2. The fan 63 is used to blow the heat generated by the heating pipe 62 into the mixing barrel 2. When the fan 63 is running, an airflow can be generated. The heating pipe 62 can heat the air in the air supply bin 61 to form a hot air flow. The hot air flow can be blown onto the raw material powder to promote the drying of the raw material powder, thereby improving the fluidity of the raw material powder and making the mixing effect of the raw material powder more uniform.

[0036] like Figure 1 and Figure 4As shown, further, the screening hopper 7 includes a screening bin 71, a first feeding pipe 72, a second feeding pipe 73 and an annular screen 74, the screening bin 71 is arranged at the discharge end of the mixing barrel 2, the first feeding pipe 72 and the second feeding pipe 73 are arranged in the screening bin 71, the annular screen 74 is arranged above the first feeding pipe 72, and the annular screen 74 is abutted against the end of the mixing barrel 2, the first feeding pipe 72 is used to receive the raw material powder screened by the annular screen 74, so as to guide the screened raw material powder to the next stage of processing or collection equipment. It should be noted that the bottom of the first feeding pipe 72 is connected to the external negative pressure suction pipeline to transport the screened raw material powder to the next process through the negative pressure force; and the second feeding pipe 73 can uniformly guide and collect the raw material powder that has not been screened.

[0037] Furthermore, the mixing barrel 2 is tilted on the machine base 1, and the height of the mixing barrel 2 gradually decreases from the hot air conveying mechanism 6 to the screening hopper 7. The tilted mixing barrel 2 can promote the API powder to move downward along the inclined surface, thereby increasing the fluidity of the material, allowing the API powder to flow smoothly from the mixing barrel 2 to the screening hopper 7, and reducing the resistance of the API powder during mixing and conveying.

[0038] like Figure 3 As shown, further, an arc-shaped guide groove 51 is provided at the bottom of the feed hopper 5, and the material bearing surface of the arc-shaped guide groove 51 is away from the air supply bin 61, and the arc-shaped guide groove 51 is used to guide the raw material powder to be transported into the mixing barrel 2. The provision of the arc-shaped guide groove 51 can control the flow direction of the raw material powder, and prevent the raw material powder from falling into the air supply bin 61 during the material guiding, so as to reduce the waste of resources.

[0039] like Figure 1 As shown, further, a receiving bucket 8 is provided at the bottom of the second drop pipe 73, and the receiving bucket 8 is used to receive the raw material drug powder that has not been screened by the annular screen 74, so as to uniformly collect the raw material drug powder for processing in other processes, avoid waste of raw material drug powder, and improve resource utilization.

[0040] As described above, the above embodiments are only used to illustrate the technical solutions of the utility model, rather than to limit it. Although the utility model has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that the technical solutions described in the aforementioned embodiments can still be modified, or some of the technical features can be replaced by equivalents. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the various embodiments of the utility model.

Claims

1. A pharmaceutical powder uniform mixing device, characterized in that: It includes a machine base, a mixing barrel, a rotary support assembly, a rotary drive mechanism, a feed hopper, a hot air conveying mechanism and a screening hopper; The bottom of the mixing drum is connected to the machine base through the rotary support assembly, and the rotary drive mechanism is in transmission connection with the mixing drum to drive the mixing drum to rotate on the rotary support assembly; The feed hopper is connected to the top of the mixing barrel, and is used to convey the raw material drug powder into the mixing barrel. The hot air conveying mechanism is provided at one end of the mixing barrel, and is used to convey the hot air flow toward the mixing barrel. The screening hopper is provided at the other end of the mixing barrel, and is used to screen the raw material drug powder after mixing. The mixing barrel is provided with a plurality of arc-shaped flow-dividing pieces arranged at intervals along the inner wall, and a flow-dividing channel for the raw material drug powder to flow is formed between two adjacent arc-shaped flow-dividing pieces. The arc-shaped flow-dividing pieces are used to divert the raw material drug powder in the mixing barrel.

2. The pharmaceutical powder uniform mixing device according to claim 1, characterized in that: The rotary drive mechanism includes a drive motor, a pulley transmission assembly, a rotating shaft, a drive gear and an endless chain; The annular chain is sleeved on the circumferential outer wall of the mixing barrel, the rotating shaft is mounted on the machine base through a bearing seat, and the rotating shaft is arranged parallel to the mixing barrel, the driving gear is arranged on the rotating shaft and meshed with the annular chain, and the output shaft of the driving motor is connected to the rotating shaft through the pulley transmission assembly to drive the rotating shaft to rotate.

3. The pharmaceutical powder uniform mixing device according to claim 2, characterized in that: The slewing support assembly includes a rubber ring and a pulley; The two rubber sleeves are respectively arranged on the mixing barrel at both sides of the annular chain, the pulley is arranged on the machine base below the rubber sleeve, and the pulley is provided with a receiving slide groove for abutting against the rubber sleeve.

4. The pharmaceutical powder uniform mixing device according to claim 1, characterized in that: The hot air delivery mechanism includes an air supply bin, a heating pipe and a fan; The air supply bin is communicated with the mixing barrel, the heating pipe is arranged in the air supply bin, the fan is arranged on a side of the air supply bin away from the mixing barrel, and the fan is used to blow the heat generated by the heating pipe into the mixing barrel.

5. The pharmaceutical powder uniform mixing device according to claim 1, characterized in that: The screening hopper comprises a screening bin, a first material dropping pipe, a second material dropping pipe and an annular screen; The screening bin is arranged at the discharge end of the mixing barrel, the first drop pipe and the second drop pipe are arranged in the screening bin, the annular screen is arranged above the first drop pipe, and the annular screen is abutted against the end of the mixing barrel, and the first drop pipe is used to receive the raw material powder screened by the annular screen.

6. The pharmaceutical powder uniform mixing device according to claim 1, characterized in that: The mixing barrel is tiltedly arranged on the machine base, and the height of the mixing barrel gradually decreases from the hot air conveying mechanism to the screening hopper.

7. The pharmaceutical powder uniform mixing device according to claim 4, characterized in that: An arc-shaped material guide trough is provided at the bottom of the feed hopper, the material bearing surface of the arc-shaped material guide trough is away from the air supply bin, and the arc-shaped material guide trough is used to guide and transport the raw material powder into the mixing barrel.

8. The pharmaceutical powder uniform mixing device according to claim 5, characterized in that: A material receiving bucket is provided at the bottom of the second drop pipe, and the material receiving bucket is used to receive the raw material powder that has not been screened by the annular screen.