A workbench for extracting and purifying reagents

Abstract

This utility model discloses a reagent extraction and purification workbench, including a workbench, a moving mechanism, a lifting mechanism, a linkage mechanism, and a drying mechanism. A base plate slides on the top of the workbench, and a side plate is welded to one side of the top of the base plate. Test tube racks and cleaning boxes are respectively located on the upper sides of the base plate. A vertical plate is welded to one side of the top of the workbench, and a T-shaped plate is welded to the top of one side of the vertical plate. A stirring shaft is rotatably connected to the bottom of the T-shaped plate, and stirring blades are welded to the outer periphery of the stirring shaft. The moving mechanism drives the base plate to move, the lifting mechanism drives the test tube racks and cleaning boxes to alternately rise and fall, the linkage mechanism drives multiple stirring shafts to rotate, and the drying mechanism dries the stirring blades. This utility model can mix samples from multiple test tubes simultaneously, improving work efficiency. After use, the stirring blades can be automatically cleaned and dried to prevent sample contamination from affecting the next operation. No manual operation is required, saving time and effort and increasing work efficiency.

Description

Technical Field

[0001] The utility model relates to the field of biotechnology, in particular to an extraction and purification reagent workbench. Background Art

[0002] In the fields of scientific research, clinical diagnosis, biopharmaceuticals, genetic engineering and transgenic technology, molecular biology operations, cell culture and research, nucleic acids, proteins and cells need to be extracted and purified for further analysis and processing. When extracting and purifying nucleic acids, proteins and cells, the sample needs to be added to the lysis buffer first, mixed thoroughly, so that the cells or tissues are lysed and the target molecules are released, thereby facilitating the extraction and purification.

[0003] However, the existing extraction and purification reagent workbench cannot stir and mix samples in multiple test tubes at one time when lysing nucleic acids, proteins, cells, etc., and after stirring, the stirring tool needs to be manually cleaned and dried to prevent the sample contaminated on its surface from affecting the next work. Manual operation is time-consuming and labor-intensive, and work efficiency is low. Utility Model Content

[0004] The utility model aims to solve the shortcomings in the prior art and proposes an extraction and purification reagent workbench.

[0005] In order to achieve the above purpose, the utility model adopts the following technical solutions:

[0006] A reagent extraction and purification workbench, comprising: a workbench, the top of the workbench is slidably connected to a bottom plate, a side plate is vertically welded to one side of the top of the bottom plate, a test tube rack and a cleaning box are horizontally arranged on both sides above the bottom plate, a vertical plate is vertically welded to one side of the top of the workbench, a T-shaped plate is horizontally welded to the top of one side of the vertical plate, a stirring shaft is vertically rotatably connected to the bottom of the T-shaped plate, and a stirring blade is welded to the outer periphery of the stirring shaft;

[0007] A moving mechanism, wherein the moving mechanism is used to drive the bottom plate to move;

[0008] A lifting mechanism, the lifting mechanism is used to drive the test tube rack and the cleaning box to alternately rise and fall;

[0009] A linkage mechanism, wherein the linkage mechanism is used to drive the multiple stirring shafts to rotate;

[0010] A drying mechanism is used to dry the stirring blades.

[0011] As a further technical solution of the utility model, a transverse groove is horizontally opened in the middle of the top of the workbench, pulleys are welded on both sides of the bottom of the bottom plate, and the two pulleys are slidably connected to the inside of the transverse groove, the top of the cleaning box is an open structure, and the bottom of one side of the outside of the cleaning box is horizontally connected to a sewage pipe, and a valve is installed on the sewage pipe.

[0012] As a further technical solution of the utility model, both ends of the inner side of the side plate are vertically provided with vertical grooves, and sliders are welded to one end of the test tube rack and the cleaning box, and the two sliders are slidably connected to the inside of the two vertical grooves respectively.

[0013] As a further technical solution of the utility model, the moving mechanism includes an electric slide, which is horizontally fixedly installed on one side of the top of the workbench, and the output end of the electric slide is fixedly connected to the side of the base plate.

[0014] Start the electric slide to drive the bottom plate to move back and forth, the bottom plate drives the side plate to move back and forth, and then drives the test tube rack and cleaning box in front of the side plate to move back and forth.

[0015] As a further technical solution of the utility model, the lifting mechanism includes a forward and reverse motor, which is horizontally fixedly installed on the outer side of the side plate, and the output shaft of the forward and reverse motor is horizontally fixedly installed with a rotating shaft, which passes through the side plate and is rotatably connected to the side plate. It is characterized in that a second gear is fixedly installed on the front end of the rotating shaft, and racks are vertically meshed on opposite sides of the second gear, and connecting blocks are welded to the sides of the two racks, and the two connecting blocks are respectively welded to the sides of the test tube rack and the cleaning box.

[0016] Starting the forward and reverse motor drives the shaft to rotate, and the shaft drives the second gear to rotate, which drives the two racks to move upward and downward respectively. The two racks drive the test tube rack and the cleaning box to move upward or downward through the connecting block, thereby moving the stirring blade into or out of the test tube rack and the cleaning box.

[0017] As a further technical solution of the utility model, the stirring shaft and stirring blade are both provided in plurality, the plurality of stirring shafts are evenly distributed laterally at the bottom of the T-shaped plate, and the plurality of stirring blades are evenly distributed around the periphery of the plurality of stirring shafts.

[0018] As a further technical solution of the utility model, the linkage mechanism includes a driving shaft and a driven shaft, and two of the driving shafts and the driven shafts are provided, and the two driving shafts are horizontally rotatably connected to the two ends of one side of the vertical plate, and the front ends of the two driving shafts are welded with driven gears, and the rotating shaft is welded with a driving gear, and the driving gear can be meshed with the two driven gears respectively, and the two driving shafts are welded with driving bevel gears, and the tops of the two driving bevel gears are meshed with driven bevel gears, and the two driven shafts are vertically welded to the centers of the two driven bevel gears, and the tops of the two driven shafts are rotatably connected to the bottom of the T-shaped plate, and a belt is connected between one of the stirring shafts and the two driven shafts, and first gears are welded on multiple stirring shafts, and adjacent first gears are meshed with each other.

[0019] The rotating shaft drives the driving gear to rotate, the driving gear drives the driving shaft to rotate through the driven gear, the driving shaft drives the driven shaft to rotate through the driving bevel gear and the driven bevel gear, the driving shaft drives one of the stirring shafts to rotate through the belt, the stirring shaft drives the other stirring shafts to rotate in turn through the first gear, thereby driving the stirring blade to rotate to fully mix the sample and lysate in the test tube, so that the cells or tissues are lysed to release the target molecules, and the samples in multiple test tubes can be stirred and mixed at one time, thereby improving work efficiency; and the rotation of the stirring blade can also make it cleaner and faster when cleaning in the cleaning box.

[0020] As a further technical solution of the utility model, the drying mechanism includes a hot air blower, which is fixedly installed on one side of the cleaning box. The air outlet of the hot air blower is connected to an air outlet pipe, the top of the air outlet pipe is horizontally connected to a horizontal pipe, and a nozzle is installed on the horizontal pipe. There are multiple nozzles and they are evenly distributed laterally on the horizontal pipe, and the multiple nozzles are all aimed at the stirring blades.

[0021] Start the hot air blower to generate hot air, and the hot air is sprayed from multiple nozzles through the air outlet pipe and the cross pipe to multiple stirring blades to dry them. The stirring blades can be automatically cleaned and dried after use to prevent the samples contaminated on their surface from affecting the next work. No manual operation is required, which saves time and effort and improves work efficiency.

[0022] The beneficial effects of the utility model are as follows: samples in multiple test tubes can be stirred and mixed at one time, thereby improving work efficiency; the stirring blade can be automatically cleaned and dried after use to prevent the sample contaminated on its surface from affecting the next work, without the need for manual operation, thus saving time and effort and increasing work efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 This is a structural schematic diagram of an extraction and purification reagent workbench proposed by the utility model;

[0024] Figure 2This is a rear structural schematic diagram of an extraction and purification reagent workbench proposed by the utility model;

[0025] Figure 3 This is a side view structural schematic diagram of an extraction and purification reagent workbench proposed by the utility model;

[0026] Figure 4 The utility model is a schematic diagram of a partial top view of the structure of an extraction and purification reagent workbench proposed by the utility model.

[0027] In the figure: 1. T-plate; 2. vertical plate; 3. slider; 4. vertical groove; 5. electric slide; 6. horizontal groove; 7. test tube rack; 8. bottom plate; 9. workbench; 10. drain pipe; 11. cleaning box; 12. stirring blade; 13. first gear; 14. stirring shaft; 15. second gear; 16. rack; 17. connecting block; 18. nozzle; 19. horizontal pipe; 20. air outlet pipe; 21. hot air blower; 22. driven gear; 23. driving shaft; 24. driven shaft; 25. belt; 26. driven bevel gear; 27. driving bevel gear; 28. pulley; 29. ​​driving gear; 30. forward and reverse motor; 31. rotating shaft; 32. side plate. DETAILED DESCRIPTION

[0028] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further described below in conjunction with specific implementation methods.

[0029] Please see attached Figure 1 -Attached Figure 4 , a reagent extraction and purification workbench, comprising: a workbench 9, a bottom plate 8 is slidably connected to the top of the workbench 9, a side plate 32 is vertically welded to one side of the top of the bottom plate 8, a test tube rack 7 and a cleaning box 11 are horizontally arranged on both sides above the bottom plate 8, a vertical plate 2 is vertically welded to one side of the top of the workbench 9, a T-shaped plate 1 is horizontally welded to the top of one side of the vertical plate 2, a stirring shaft 14 is vertically rotatably connected to the bottom of the T-shaped plate 1, and a stirring blade 12 is welded to the outer periphery of the stirring shaft 14;

[0030] A moving mechanism, the moving mechanism is used to drive the bottom plate 8 to move;

[0031] A lifting mechanism, the lifting mechanism is used to drive the test tube rack 7 and the cleaning box 11 to alternately lift and lower;

[0032] A linkage mechanism, which is used to drive the multiple stirring shafts 14 to rotate;

[0033] The drying mechanism is used to dry the stirring blade 12 .

[0034] Please see attached Figure 1 and 3In a preferred embodiment, a transverse groove 6 is horizontally opened in the middle of the top of the workbench 9, pulleys 28 are welded on both sides of the bottom of the bottom plate 8, and the two pulleys 28 are slidably connected to the inside of the transverse groove 6, the top of the cleaning box 11 is an open structure, and the bottom of one side of the outside of the cleaning box 11 is horizontally connected to a sewage pipe 10, and a valve is installed on the sewage pipe 10.

[0035] The pulley 28 slides in the transverse groove 6 to make the movement of the bottom plate 8 smoother, and the valve can be opened to discharge the washed sewage inside the cleaning box 11 through the sewage pipe 10.

[0036] Please see attached Figure 1 In a preferred embodiment, vertical grooves 4 are vertically opened at both ends of the inner side of the side plate 32, and sliders 3 are welded to one end of the test tube rack 7 and the cleaning box 11, and the two sliders 3 are slidably connected to the inside of the two vertical grooves 4 respectively.

[0037] The slide block 3 slides inside the vertical groove 4 to support and limit the lifting and lowering of the test tube rack 7 and the cleaning box 11.

[0038] Please see attached Figure 1 and 3 In a preferred embodiment, the moving mechanism includes an electric slide 5, which is horizontally fixedly installed on one side of the top of the workbench 9, and the output end of the electric slide 5 is fixedly connected to the side of the base plate 8.

[0039] The electric slide 5 is started to drive the bottom plate 8 to move back and forth, and the bottom plate 8 drives the side plate 32 to move back and forth, which drives the test tube rack 7 and the cleaning box 11 in front of the side plate 32 to move back and forth.

[0040] Please see attached Figure 1 In a preferred embodiment, the lifting mechanism includes a forward and reverse motor 30, which is horizontally fixedly installed on the outer side of the side plate 32, and the output shaft of the forward and reverse motor 30 is horizontally fixedly installed with a rotating shaft 31, which passes through the side plate 32 and is rotatably connected to the side plate 32.

[0041] Please see attached Figure 1 In a preferred embodiment, a second gear 15 is fixedly mounted on the front end of the rotating shaft 31, and racks 16 are vertically meshed on opposite sides of the second gear 15, and connecting blocks 17 are welded to the sides of the two racks 16, and the two connecting blocks 17 are respectively welded to the sides of the test tube rack 7 and the cleaning box 11.

[0042] The forward and reverse motor 30 is started to drive the rotating shaft 31 to rotate, and the rotating shaft 31 drives the second gear 15 to rotate, which drives the two racks 16 to move upward and downward respectively. The two racks 16 drive the test tube rack 7 and the cleaning box 11 to move upward or downward through the connecting block 17, thereby moving the stirring blade 12 into or out of the test tube rack 7 and the cleaning box 11.

[0043] Please see attached Figure 1-4 In a preferred embodiment, the stirring shaft 14 and the stirring blade 12 are both provided with a plurality, and the plurality of stirring shafts 14 are evenly distributed in the horizontal direction at the bottom of the T-shaped plate 1 , and the plurality of stirring blades 12 are evenly distributed around the periphery of the plurality of stirring shafts 14 .

[0044] Please see attached Figure 3 and 4 In a preferred embodiment, the linkage mechanism includes a driving shaft 23 and a driven shaft 24, and two driving shafts 23 and two driven shafts 24 are provided, and the two driving shafts 23 are respectively connected to the two ends of one side of the vertical plate 2 for horizontal rotation, and the front ends of the two driving shafts 23 are welded with driven gears 22, and a driving gear 29 is welded on the rotating shaft 31. The driving gear 29 can be respectively engaged with the two driven gears 22, and the two driving shafts 23 are welded with driving bevel gears 27, and the tops of the two driving bevel gears 27 are meshed with driven bevel gears 26.

[0045] Please see attached Figure 3 and 4 In a preferred embodiment, the two driven shafts 24 are vertically welded to the centers of the two driven bevel gears 26, the top ends of the two driven shafts 24 are rotatably connected to the bottom of the T-plate 1, and a belt 25 is connected between one of the stirring shafts 14 and the two driven shafts 24, and the first gears 13 are welded on the multiple stirring shafts 14, and the adjacent first gears 13 are meshed with each other.

[0046] The rotating shaft 21 drives the driving gear 29 to rotate, and the driving gear 29 drives the driving shaft 23 to rotate through the driven gear 22, and the driving shaft 23 drives the driven shaft 24 to rotate through the driving bevel gear 27 and the driven bevel gear 26, and the driving shaft 23 drives one of the stirring shafts 14 to rotate through the belt 25, and the stirring shaft 14 drives the other stirring shafts 14 to rotate in turn through the first gear 13, thereby driving the stirring blade 12 to rotate to fully mix the sample and the lysate in the test tube, so that the cells or tissues are lysed to release the target molecules, and the samples in multiple test tubes can be stirred and mixed at one time, thereby improving work efficiency; and the rotation of the stirring blade 12 can also make it cleaner and faster when cleaning in the cleaning box 11.

[0047] Please see attached Figure 2-4 In a preferred embodiment, the drying mechanism includes a hot air blower 21, which is fixedly installed on one side of the cleaning box 11. The air outlet of the hot air blower 21 is connected to an air outlet pipe 20. The top of the air outlet pipe 20 is horizontally connected to a transverse pipe 19. A nozzle 18 is installed on the transverse pipe 19. There are multiple nozzles 18 and they are evenly distributed laterally on the transverse pipe 19, and the multiple nozzles 18 are all aimed at the stirring blade 12.

[0048] Start the hot air blower 21 to generate hot air, and the hot air is sprayed by multiple nozzles 18 to multiple stirring blades 12 through the air outlet pipe 20 and the cross pipe 19 to dry them. The stirring blades 12 can be automatically cleaned and dried after use to prevent the sample contaminated on the surface from affecting the next work. No manual operation is required, which saves time and effort and improves work efficiency.

[0049] From the above description, it can be seen that the above-mentioned embodiment of the utility model achieves the following technical effects: multiple test tubes containing samples and lysate are placed in the test tube rack 7 in sequence, and clean water is added to the cleaning box 11, the electric slide 5 is started to drive the bottom plate 8 to move, and the bottom plate 8 drives the side plate 32 to move, which drives the test tube rack 7 and the cleaning box 11 in front of the side plate 32 to move until the test tube rack 7 moves to the bottom of the stirring blade 12;

[0050] The forward and reverse motor 30 is started to drive the rotating shaft 31 to rotate, and the rotating shaft 31 drives the second gear 15 to rotate, which drives the two racks 16 to move upward and downward respectively. The two racks 16 drive the test tube rack 7 to move upward and the cleaning box 11 to move downward respectively through the connecting block 17, so that the multiple stirring blades 12 are respectively extended into the multiple test tubes in the test tube rack 7. At this time, the racks 16 and the second gear 15 are meshed;

[0051] The forward and reverse motor 30 is started to continue to drive the rotating shaft 31 to rotate. Since the rack 16 and the second gear 15 are fully engaged, the continued rotation of the second gear 15 will not cause the position of the rack 16 to change, that is, the positions of the test tube rack 7 and the cleaning box 11 remain unchanged; the rotating shaft 31 drives the driving gear 29 to rotate, the driving gear 29 drives the driving shaft 23 to rotate through the driven gear 22, the driving shaft 23 drives the driven shaft 24 to rotate through the driving bevel gear 27 and the driven bevel gear 26, the driving shaft 23 drives one of the stirring shafts 14 to rotate through the belt 25, the stirring shaft 14 drives the other stirring shafts 14 to rotate in turn through the first gear 13, thereby driving the stirring blade 12 to rotate to fully mix the sample and the lysate in the test tube, so that the cells or tissues are lysed to release the target molecules, and the samples in multiple test tubes can be stirred and mixed at one time, thereby improving work efficiency;

[0052] When the cells or tissues are lysed, the forward and reverse motor 30 is started to rotate its output shaft in the reverse direction, driving the test tube rack 7 and the cleaning box 11 to return to their original positions, and the electric slide 5 is started again to drive the test tube rack 7 and the cleaning box 11 to move until the cleaning box 11 moves to the bottom of the stirring blade 12;

[0053] Similarly, the cleaning box 11 is driven to rise, so that the plurality of stirring blades 12 are all extended into the cleaning box 11. Similarly, the stirring blades 12 are driven to rotate, so that the cleaning in the cleaning box 11 can be cleaned more cleanly and quickly.

[0054] After cleaning is completed, the forward and reverse motor 30 is started to rotate its output shaft in the reverse direction, driving the test tube rack 7 and the cleaning box 11 to return to their original positions, and the hot air blower 21 is started to generate hot air, which is sprayed to the multiple stirring blades 12 through the air outlet pipe 20 and the cross pipe 19 by the multiple nozzles 18 to dry them. The stirring blades 12 can be automatically cleaned and dried after use to prevent the sample contaminated on the surface from affecting the next work. No manual operation is required, which saves time and effort and has higher work efficiency.

[0055] Those skilled in the art should understand that the discussion of any of the above embodiments is merely illustrative and is not intended to imply that the scope of the present invention (including the claims) is limited to these examples. Under the concept of the present invention, the technical features in the above embodiments or different embodiments may be combined, the steps may be implemented in any order, and there are many other variations of the different aspects of the present invention as described above, which are not provided in detail for the sake of simplicity.

[0056] The utility model is intended to cover all such substitutions, modifications and variations that fall within the broad scope of the claims. Therefore, any omissions, modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the utility model should be included in the scope of protection of the utility model.

Claims

1. An extraction and purification reagent workbench, characterized in that: include: A workbench (9), wherein the top of the workbench (9) is slidably connected to a bottom plate (8), a side plate (32) is vertically welded to one side of the top of the bottom plate (8), a test tube rack (7) and a cleaning box (11) are horizontally arranged on both sides above the bottom plate (8), a vertical plate (2) is vertically welded to one side of the top of the workbench (9), a T-shaped plate (1) is horizontally welded to the top of one side of the vertical plate (2), a stirring shaft (14) is vertically rotatably connected to the bottom of the T-shaped plate (1), and a stirring blade (12) is welded to the outer periphery of the stirring shaft (14); A moving mechanism, the moving mechanism is used to drive the bottom plate (8) to move; A lifting mechanism, the lifting mechanism is used to drive the test tube rack (7) and the cleaning box (11) to alternately lift and lower; A linkage mechanism, the linkage mechanism being used to drive the plurality of stirring shafts (14) to rotate; A drying mechanism, wherein the drying mechanism is used to dry the stirring blade (12).

2. The extraction and purification reagent workbench according to claim 1, characterized in that: A transverse groove (6) is horizontally provided in the middle of the top of the workbench (9), pulleys (28) are welded on both sides of the bottom of the bottom plate (8), and the two pulleys (28) are slidably connected to the inside of the transverse groove (6), the top of the cleaning box (11) is an open structure, and the bottom of one side of the outside of the cleaning box (11) is horizontally connected to a sewage pipe (10), and a valve is installed on the sewage pipe (10).

3. The extraction and purification reagent workbench according to claim 1, characterized in that: Both ends of the inner side of the side plate (32) are vertically provided with vertical grooves (4), and one end of the test tube rack (7) and the cleaning box (11) are welded with sliders (3), and the two sliders (3) are slidably connected to the inside of the two vertical grooves (4) respectively.

4. The extraction and purification reagent workbench according to claim 1, characterized in that: The moving mechanism comprises an electric slide (5), wherein the electric slide (5) is horizontally fixedly installed on one side of the top of the workbench (9), and the output end of the electric slide (5) is fixedly connected to the side of the base plate (8).

5. The extraction and purification reagent workbench according to claim 1, characterized in that: The lifting mechanism comprises a forward and reverse motor (30), the forward and reverse motor (30) being fixedly mounted horizontally on the outside of the side plate (32), the output shaft of the forward and reverse motor (30) being fixedly mounted horizontally with a rotating shaft (31), the rotating shaft (31) passing through the side plate (32) and being rotatably connected to the side plate (32).

6. The extraction and purification reagent workbench according to claim 5, characterized in that: A second gear (15) is fixedly mounted on the front end of the rotating shaft (31), and racks (16) are vertically meshed on opposite sides of the second gear (15), and connecting blocks (17) are welded to the sides of the two racks (16), and the two connecting blocks (17) are respectively welded to the sides of the test tube rack (7) and the cleaning box (11).

7. The extraction and purification reagent workbench according to claim 6, characterized in that: The stirring shafts (14) and stirring blades (12) are both provided in plurality, the plurality of stirring shafts (14) are evenly distributed in the transverse direction at the bottom of the T-shaped plate (1), and the plurality of stirring blades (12) are evenly distributed around the periphery of the plurality of stirring shafts (14).

8. The extraction and purification reagent workbench according to claim 7, characterized in that: The linkage mechanism comprises a driving shaft (23) and a driven shaft (24), two of the driving shafts (23) and two of the driven shafts (24) are provided, and the two driving shafts (23) are respectively connected to two ends of one side of the vertical plate (2) in a horizontally rotatable manner, and the front ends of the two driving shafts (23) are welded with driven gears (22), and the rotating shaft (31) is welded with a driving gear (29), and the driving gear (29) can be meshed with the two driven gears (22) respectively, and the two driving shafts (23) are welded with driving bevel gears (27), and the tops of the two driving bevel gears (27) are meshed with driven bevel gears (26).

9. The extraction and purification reagent workbench according to claim 8, characterized in that: The two driven shafts (24) are respectively vertically welded to the centers of the two driven bevel gears (26); the top ends of the two driven shafts (24) are rotatably connected to the bottom of the T-shaped plate (1); a belt (25) is connected between one of the stirring shafts (14) and the two driven shafts (24); a plurality of the stirring shafts (14) are welded with first gears (13), and adjacent first gears (13) are meshed with each other.

10. The extraction and purification reagent workbench according to claim 1, characterized in that: The drying mechanism comprises a hot air blower (21), the hot air blower (21) is fixedly mounted on one side of the cleaning box (11), the air outlet of the hot air blower (21) is connected to an air outlet pipe (20), the top end of the air outlet pipe (20) is horizontally connected to a transverse pipe (19), a nozzle (18) is mounted on the transverse pipe (19), a plurality of nozzles (18) are provided and are evenly distributed in the transverse direction on the transverse pipe (19), and the plurality of nozzles (18) are all aimed at the stirring blade (12).

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