A purification column device for gel purification system

By designing a purification column device for the pressure regulating assembly and fixed adjustment assembly in the gel purification system, the gel damage caused by the increase in the pressure inside the purification column is solved, and effective pressure regulating and purification effect are improved.

CN222738544UActive Publication Date: 2025-04-11JIANGSU HUAMEICHEN INSTR TECH CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202421291443.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-07
Publication Date
2025-04-11
Estimated Expiration
2034-06-07

AI Technical Summary

Technical Problem

In the existing gel purification system, the gradual increase in the internal pressure of the purification column will damage the gel chromatography column, causing the purification filler to deform or rupture, reducing the separation efficiency and purification effect.

Method used

A purification column device including a pressure regulating assembly and a fixed adjustment assembly is designed. The pressure inside the purification column is monitored and adjusted by a pressure sensor to avoid damage to the gel by excessive pressure, and the internal pressure is adaptively adjusted by relative fixation or separation of the L-shaped adjustment plate and the fixation plate.

Benefits of technology

It effectively avoids damage to the gel due to excessive pressure, ensures the separation efficiency of the purification filler and the purification effect of the purification column, and improves the stability and service life of the device.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN222738544U_ABST
    Figure CN222738544U_ABST
Patent Text Reader

Abstract

The utility model provides a purification column device for a gel purification system, which belongs to the technical field of gel purification devices, and comprises: a purification column body and an upper sealing plug, wherein the upper sealing plug is arranged at the upper end of the purification column body, and a sealing plate is slidably connected to the inside of the purification column body in a sealed manner; a pressure regulating component, wherein the pressure regulating component comprises two first through holes provided on the upper sealing plug, and lifting and adjusting rods are slidably connected in the two first through holes, and the lower ends of the two lifting and adjusting rods are fixedly connected to the sealing plate, and an adjusting driving component is arranged on the upper sealing plug. In the utility model, the internal pressure of the purification column body can be adjusted and balanced in time to avoid damage to the gel due to excessive pressure, thereby ensuring the separation efficiency of the purification filler and the purification effect of the purification column, and the upper sealing plug can be conveniently loaded and unloaded, which is beneficial to improving the stability of the purification column body during use, and can further maintain the balance of the internal pressure of the purification column device.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The utility model relates to the technical field of gel purification devices, in particular to a purification column device used in a gel purification system. Background Art

[0002] The gel purification system refers to the technology of using gel to purify various liquids including water. The pollutants and impurities in the liquid are adsorbed by the special material of the gel to achieve the liquid purification effect. The structure of the gel itself has many tiny pores that can capture tiny impurities in the liquid. When the liquid passes through the gel, the impurities can be removed and purification can be achieved.

[0003] The existing technology often has the following problems when used:

[0004] When the purification column is used for a long time, the pressure of the gas inside it will increase, causing the internal pressure of the purification column to gradually increase. If the internal pressure of the purification column is not adjusted in time, the excessive pressure will easily damage the gel chromatography column, causing the purification filler in the purification column to deform or even rupture, thereby reducing the separation efficiency of the purification filler and affecting the gel purification effect. Utility Model Content

[0005] In view of the deficiencies in the prior art, the utility model provides a purification column device for a gel purification system.

[0006] The embodiment of the utility model provides a purification column device for a gel purification system, comprising:

[0007] A purification column body and an upper sealing plug, wherein the upper sealing plug is arranged at the upper end of the purification column body, and a sealing plate is sealingly and slidably connected inside the purification column body;

[0008] A pressure regulating assembly, the pressure regulating assembly comprising two first through holes opened on the upper sealing plug, the two first through holes are slidably connected with lifting adjustment rods, the lower ends of the two lifting adjustment rods are fixedly connected to the sealing plate, and the upper sealing plug is provided with an adjustment driving component;

[0009] A fixed adjustment component includes an L-shaped adjustment plate fixedly connected to the outer wall of the upper sealing plug, a fixed plate fixedly connected to the upper end of the outer wall of the purification column body, a plurality of threaded holes are opened on the fixed plate, and a fixing bolt is threadedly connected through the L-shaped adjustment plate, and the fixing bolt matches the threaded hole.

[0010] Furthermore, the adjustment drive component includes a lifting screw rotatably connected to the top of the upper sealing plug, the lifting screw is threadedly connected to a lifting slider, the lifting slider is fixedly connected to an adapter plate, the upper ends of the two lifting adjustment rods are fixedly connected to the adapter plate, and a rotating motor is fixedly connected to the top of the upper sealing plug via a fixed bracket, and the output end of the rotating motor is fixedly connected to the upper end of the lifting screw.

[0011] Furthermore, an air pressure sensor is installed on the upper sealing plug, the air pressure sensor is electrically connected to the rotary motor, a second through hole is opened on the sealing plate, and a sensing probe of the air pressure sensor is located at the second through hole.

[0012] Furthermore, a filter plate is fixedly connected to the lower end of the inner wall of the purification column body, and a discharge pipe is provided at the lower end of the purification column body.

[0013] Furthermore, a feed pipe is fixedly connected to the upper sealing plug, a third through hole is opened on the sealing plate, the lower end of the feed pipe matches the third through hole, and the ends of the feed pipe and the discharge pipe outside the purification column body are both provided with sealing covers.

[0014] Furthermore, silicone sealing rings are provided at the first through hole, the second through hole and the third through hole.

[0015] Compared with the prior art, the utility model has the following beneficial effects:

[0016] The utility model is provided with a pressure regulating assembly, and uses an air pressure sensor to monitor the pressure inside the purification column body. When the pressure inside the purification column body increases, the sealing plate is driven to move upward to balance the internal pressure of the purification column body, so that the internal pressure of the purification column device can be adjusted in time, avoiding damage to the gel due to excessive pressure, and ensuring the separation efficiency of the purification filler and the purification effect of the purification column;

[0017] A fixed adjustment component is provided in the utility model, which can facilitate the loading and unloading of the upper sealing plug by realizing the relative fixation or separation of the L-shaped adjustment plate and the fixed plate on the purification column body, which is beneficial to improving the stability of the purification column body during use. At the same time, the internal pressure of the purification column body can be adaptively adjusted by adjusting the relative fixed position of the L-shaped adjustment plate and the fixed plate, which is beneficial to further maintain the balance of the internal pressure of the purification column device. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic diagram of the three-dimensional structure of a purification column device used in a gel purification system described in an embodiment of the utility model.

[0019] Figure 2 It is a cross-sectional view of a purification column body in a purification column device for a gel purification system described in an embodiment of the utility model.

[0020] Figure 3 It is a schematic diagram of the structure of an upper sealing plug and a sealing plate in a purification column device for a gel purification system described in an embodiment of the utility model.

[0021] In the above drawings: 1 purification column body, 2 upper sealing plug, 3 sealing plate, 4 first through hole, 5 lifting adjustment rod, 6 L-shaped adjustment plate, 7 fixing plate, 8 fixing bolt, 9 lifting screw, 10 lifting slider, 11 adapter plate, 12 rotary motor, 13 air pressure sensor, 14 second through hole, 15 filter plate, 16 discharge pipe, 17 feed pipe, 18 third through hole. DETAILED DESCRIPTION

[0022] The technical solution of the present utility model is further described below in conjunction with the accompanying drawings and embodiments.

[0023] like Figure 1-Figure 3 As shown, the embodiment of the utility model proposes a purification column device for a gel purification system, including a purification column body 1, an upper sealing plug 2, a pressure regulating assembly and a fixed regulating assembly: the upper sealing plug 2 is arranged at the upper end of the purification column body 1, the purification column body 1 is internally sealed and slidably connected with a sealing plate 3, the lower end of the inner wall of the purification column body 1 is fixedly connected with a filter plate 15, the lower end of the purification column body 1 is provided with a discharge pipe 16, the upper sealing plug 2 is fixedly connected with a feed pipe 17, a third through hole 18 is opened on the sealing plate 3, the lower end of the feed pipe 17 matches the third through hole 18, and the ends of the feed pipe 17 and the discharge pipe 16 located outside the purification column body 1 are both provided with sealing covers;

[0024] The filter plate 15 can further remove impurities in the purification filler, and the sealing covers provided at the ends of the feed pipe 17 and the discharge pipe 16 can maintain the internal sealing of the purification column body 1.

[0025] like Figure 1-Figure 3As shown, the pressure regulating assembly includes two first through holes 4 opened on the upper sealing plug 2, and the two first through holes 4 are slidably connected with lifting adjustment rods 5, and the lower ends of the two lifting adjustment rods 5 are fixedly connected to the sealing plate 3. The upper sealing plug 2 is provided with an adjustment driving component, and the adjustment driving component includes a lifting screw 9 rotatably connected to the upper part of the upper sealing plug 2, and the lifting screw 9 is threadedly connected with a lifting slider 10, and the lifting slider 10 is fixedly connected with an adapter plate 11. The upper ends of the two lifting adjustment rods 5 are fixedly connected to the adapter plate 11, and a rotating motor 12 is fixedly connected to the upper part of the upper sealing plug 2 through a fixed bracket. The output end 12 is fixedly connected to the upper end of the lifting screw 9, and an air pressure sensor 13 is installed on the upper sealing plug 2. The air pressure sensor 13 is electrically connected to the rotary motor 12. The air pressure sensor 13 is integrated with a signal controller, and the air pressure sensor 13 and the rotary motor 12 are coupled in a closed circuit with an external power supply. It should be noted that when the internal pressure of the purification column body 1 reaches a balanced state, the air pressure sensor 13 will transmit a closing signal to the rotary motor 12 to stop the operation of the rotary motor 12. A second through hole 14 is opened on the sealing plate 3, and the sensing probe of the air pressure sensor 13 is located at the second through hole 14;

[0026] After the purification column body 1 purifies the purification filler for a period of time, the internal air pressure of the purification column body 1 will gradually increase. At this time, the internal pressure of the purification column body 1 can be monitored by the air pressure sensor 13. When the internal pressure value of the purification column body 1 reaches the target value of the air pressure sensor 13, the air pressure sensor 13 transmits a start signal to the rotary motor 12 through the signal controller to start the rotary motor 12. The rotary motor 12 drives the lifting screw 9 to rotate, so that the lifting slider 10 threadedly connected to the lifting screw 9 starts to rise and move, and then the sealing plate 3 is driven to move upward through the two lifting adjustment rods 5, so that the sealing plate 3 slides up and seals inside the purification column body 1, thereby balancing the internal pressure of the purification column body 1, so that the internal pressure of the purification column device can be adjusted in time, avoiding damage to the gel due to excessive pressure, and ensuring the separation efficiency of the purification filler and the purification effect of the purification column.

[0027] like Figure 3 As shown, silicone sealing rings are provided at the first through hole 4, the second through hole 14 and the third through hole 18;

[0028] By arranging silicone sealing rings at the first through hole 4, the second through hole 14 and the third through hole 18, the sealing performance of the lifting and lowering adjustment rod 5, the feed pipe 17 and the sensing probe of the air pressure sensor 13 relative to the sealing plate 3 can be maintained during the upward movement of the sealing plate 3, thereby ensuring the purification treatment effect of the purification column body 1.

[0029] like Figure 1 and Figure 2As shown, the fixed adjustment assembly includes an L-shaped adjustment plate 6 fixedly connected to the outer wall of the upper sealing plug 2, a fixing plate 7 is fixedly connected to the upper end of the outer wall of the purification column body 1, a plurality of threaded holes are opened on the fixing plate 7, and a fixing bolt 8 is threadedly connected through the L-shaped adjustment plate 6, and the fixing bolt 8 matches the threaded hole;

[0030] The L-shaped adjustment plate 6 and the fixed plate 7 can be installed, fixed or disassembled and separated by the fixing bolts 8, which can facilitate the loading and unloading of the upper sealing plug 2 and the purification column body 1. By directly fixing the upper sealing plug 2 on the purification column body 1, it is beneficial to improve the stability of the purification column body 1 during use. At the same time, the internal pressure of the purification column body 1 can be adaptively adjusted by adjusting the relative fixed position of the L-shaped adjustment plate 6 and the fixed plate 7, which is beneficial to further maintain the balance of the internal pressure of the purification column device.

[0031] The detailed working process of the utility model is as follows:

[0032] 1. When the purification column device is in use, the upper sealing plug 2 is installed and fixed on the upper end of the purification column body 1, and the liquid to be purified, i.e., the purification filler, is passed into the purification column body 1 through the feed pipe 17. After a period of purification, the internal air pressure of the purification column body 1 will gradually increase. At this time, the internal pressure of the purification column body 1 can be monitored by the air pressure sensor 13. When the internal pressure value of the purification column body 1 reaches the target value of the air pressure sensor 13, the air pressure sensor 13 transmits a start signal to the rotary motor 12 to start the rotary motor 12, and the rotary motor 12 drives the lifting screw 9 to rotate, so that the lifting slider 10 threadedly connected to the lifting screw 9 starts to move upward, and then the sealing plate 3 is driven to move upward through the two lifting adjustment rods 5, so that the sealing plate 3 slides up in the purification column body 1, thereby balancing the internal pressure of the purification column body 1, so that the internal pressure of the purification column device can be adjusted in time, avoiding damage to the gel due to excessive pressure, and ensuring the separation efficiency of the purification filler and the purification effect of the purification column;

[0033] 2. The L-shaped adjustment plate 6 and the fixed plate 7 can be installed, fixed or disassembled and separated by the fixing bolts 8, which can facilitate the loading and unloading of the upper sealing plug 2 and the purification column body 1. By directly fixing the upper sealing plug 2 on the purification column body 1, it is beneficial to improve the stability of the purification column body 1 during use. At the same time, the internal pressure of the purification column body 1 can be adaptively adjusted by adjusting the relative fixed position of the L-shaped adjustment plate 6 and the fixed plate 7, which is beneficial to further maintain the balance of the internal pressure of the purification column device.

[0034] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the utility model rather than to limit it. Although the utility model has been described in detail with reference to the preferred embodiments, ordinary technicians in the field should understand that the technical solution of the utility model can be modified or replaced by equivalents without departing from the purpose and scope of the technical solution of the utility model, which should be included in the scope of the claims of the utility model.

Claims

1. A purification column device for a gel purification system, characterized in that: include: A purification column body (1) and an upper sealing plug (2), wherein the upper sealing plug (2) is arranged at the upper end of the purification column body (1), and a sealing plate (3) is sealingly and slidably connected inside the purification column body (1); A pressure regulating assembly, the pressure regulating assembly comprising two first through holes (4) formed on an upper sealing plug (2), wherein the two first through holes (4) are both slidably connected with lifting and lowering regulating rods (5), the lower ends of the two lifting and lowering regulating rods (5) are both fixedly connected to the sealing plate (3), and an adjusting driving component is provided on the upper sealing plug (2); A fixed adjustment component, the fixed adjustment component comprises an L-shaped adjustment plate (6) fixedly connected to the outer wall of the upper sealing plug (2), a fixed plate (7) fixedly connected to the upper end of the outer wall of the purification column body (1), a plurality of threaded holes are opened on the fixed plate (7), and a fixing bolt (8) is threadedly connected through the L-shaped adjustment plate (6), and the fixing bolt (8) matches the threaded hole.

2. A purification column device for a gel purification system according to claim 1, characterized in that: in: The adjustment drive component comprises a lifting screw (9) rotatably connected to the upper part of the upper sealing plug (2); a lifting slider (10) is threadedly connected to the lifting screw (9); an adapter plate (11) is fixedly connected to the lifting slider (10); the upper ends of the two lifting adjustment rods (5) are fixedly connected to the adapter plate (11); a rotary motor (12) is fixedly connected to the upper part of the upper sealing plug (2) via a fixed bracket; the output end of the rotary motor (12) is fixedly connected to the upper end of the lifting screw (9).

3. A purification column device for a gel purification system according to claim 2, characterized in that: in: An air pressure sensor (13) is installed on the upper sealing plug (2), the air pressure sensor (13) is electrically connected to the rotary motor (12), a second through hole (14) is opened on the sealing plate (3), and a sensing probe of the air pressure sensor (13) is located at the second through hole (14).

4. A purification column device for a gel purification system according to claim 1, characterized in that: in: A filter plate (15) is fixedly connected to the lower end of the inner wall of the purification column body (1), and a discharge pipe (16) is provided at the lower end of the purification column body (1).

5. A purification column device for a gel purification system according to claim 4, characterized in that: in: A feed pipe (17) is fixedly connected to the upper sealing plug (2), a third through hole (18) is provided on the sealing plate (3), the lower end of the feed pipe (17) matches the third through hole (18), and the ends of the feed pipe (17) and the discharge pipe (16) located outside the purification column body (1) are both provided with sealing covers.

6. The purification column device for a gel purification system according to claim 1, characterized in that: in: The first through hole (4), the second through hole (14) and the third through hole (18) are all provided with silicone sealing rings.