Solid-phase extraction device

Abstract

The utility model relates to the field of experimental equipment, in particular to a solid-phase extraction device, which comprises a panel, a cylinder body, a sample holder and a waste liquid tank, the panel is fixed or covered on the cylinder body, and the solid-phase extraction device is characterized in that an opening is arranged on the side wall of the cylinder body; a sealing piece is arranged at the opening and connected with the cylinder body in a rotating or inserting mode. The waste liquid tank or the sample holder is placed inside the cylinder body through the opening, one of the waste liquid tank and the sample holder is placed inside the cylinder body, and the other one is placed outside the cylinder body; and the panel, the cylinder body and the sealing element form a closed cylinder chamber. According to the structure, the operation process can be simplified, meanwhile, the risk that the interior of the device and a sample are subjected to cross contamination after the panel is opened can be avoided, and the working efficiency can be improved.

Description

Technical Field

[0001] The utility model relates to the field of experimental equipment, in particular to a solid phase extraction device. Background Art

[0002] Solid-Phase Extraction, or SPE for short, is a sample preparation technique used to separate substances in a sample or purify a sample before analysis. In a commonly used solid-phase extraction device, when eluting the extraction column, it is necessary to first place a waste liquid tank with a cover inside the cylinder to receive activation, sample loading, and elution. After the operation is completed, the panel must be opened to remove the waste liquid tank, and then the sample device containing the glass test tube must be placed in the cylinder. The panel must be covered before the sample can be eluted. The operation is cumbersome and there is a risk of cross-contamination of the device and the sample after the panel is removed.

[0003] Therefore, it is necessary to provide a solid phase extraction device to solve at least one of the above technical problems. Utility Model Content

[0004] In order to overcome the above problems of cumbersome operation and the risk of cross contamination inside the device and samples after the panel is removed, the utility model provides a solid phase extraction device.

[0005] In order to solve the above technical problems, the present utility model provides the following technical solutions:

[0006] A solid phase extraction device comprises a panel, a cylinder, a sample rack and a waste liquid tank, wherein the panel is fixed or covered on the cylinder; an opening is arranged on the side wall of the cylinder; a sealing member is arranged at the opening, and the sealing member is rotatably connected or plug-connected to the cylinder; the waste liquid tank or the sample rack is placed inside the cylinder through the opening, one of the waste liquid tank and the sample rack is placed inside the cylinder, and the other is placed outside the cylinder; the panel, the cylinder and the sealing member together constitute a closed cylinder chamber.

[0007] As a further solution of the utility model: the waste liquid tank or the sample rack is slidably connected to the inner side wall of the cylinder body.

[0008] As a further solution of the utility model: a bearing portion is also provided on the sealing member, and the bearing portion is slidably connected to the inner wall of the cylinder body, and the waste liquid tank or the sample rack is carried and transported to the inside of the cylinder body through the bearing portion.

[0009] As a further solution of the utility model: the sealing member is a drawer.

[0010] As a further solution of the utility model: it also includes a valve, and the valve is connected to the cylinder body.

[0011] As a further solution of the utility model: it also includes a pressure gauge, which is connected to the valve and arranged on the valve.

[0012] As a further solution of the utility model: it also includes a plurality of purification columns, and the purification columns are connected to the panel.

[0013] As a further solution of the utility model: a control valve is provided at the lower end of the purification column.

[0014] As a further solution of the utility model: a flange is arranged on the panel toward the cylinder body.

[0015] As a further solution of the utility model: support legs are arranged on the panel toward the cylinder body.

[0016] Beneficial effects of a solid phase extraction device involved in the utility model:

[0017] Since an opening is provided on the side wall of the cylinder body, a sealing member is provided at the opening to be rotatably connected or plug-connected to the cylinder body. After elution is completed, the sealing member is opened to take out the waste liquid tank from the opening. Then the sample rack is placed into the interior of the cylinder body through the opening, and finally the sealing member is closed to continue the operation. The original cumbersome process of removing the panel and placing the sample rack for sample elution after elution is completed is simplified, the operation is simple, and the safety is high. At the same time, the risk of cross-contamination of the interior of the device and the sample after opening the panel can be avoided, and the work efficiency can be improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the specific implementation methods of the present application or the technical solutions in the prior art, the following is a brief introduction to the drawings required for use in the specific implementation methods or the description of the prior art. The drawings are used to provide a further understanding of the present application and constitute a part of the specification. Together with the following specific implementation methods, they are used to explain the present application, but do not constitute a limitation to the present application. For ordinary technicians in this field, other drawings can also be obtained based on these drawings without creative work. Elements or components with the same reference numerals in the drawings are represented as similar corresponding elements or components. Unless otherwise stated, the dimensions in the drawings do not constitute a proportional limitation.

[0019] Figure 1 This is an exploded view of the solid phase extraction device of the utility model;

[0020] Figure 2 It is a schematic diagram of the panel structure of the utility model;

[0021] Figure 3 It is a schematic diagram of the cylinder structure of the utility model;

[0022] Figure 4 This is a schematic structural diagram of the first embodiment of the sealing member of the utility model;

[0023] Figure 5 This is a schematic structural diagram of a second embodiment of the sealing member of the utility model;

[0024] Figure 6 It is a schematic diagram of the structure of the waste liquid tank of the utility model;

[0025] Figure 7 It is a schematic diagram of the structure of the sample rack of the utility model.

[0026] In the figure: 100-purification column, 10a-control valve, 200-panel, 210-entry hole, 220-panel body, 230-flange, 240-support leg, 300-cylinder, 310-cylinder side wall, 311-side wall slide, 312-first vent hole, 313-cylinder sill, 320-bottom plate, 32a-bottom plate support, 410-pressure gauge, 420-valve interface, 430-valve, 500-cylinder base, 600- Sealing part, 610-decorative part, 611-handle, 612-sealing part, 620-bearing part, 630-bearing wall, 63a-second ventilation hole, 700-waste liquid tank, 710-waste liquid tank bottom plate, 720-waste liquid tank wall, 72a-waste liquid tank sliding part, 800-sample rack, 810-support column, 820-fixing part, 830-test tube rack, 83a-test tube hole, 840-fixing plate, 841-fixing hole, 842-hand holding part. DETAILED DESCRIPTION

[0027] In order to make the purpose, technical solution and advantages of the utility model more clear, the following is a further detailed description of a solid phase extraction device of the utility model in combination with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the utility model and are not used to limit the utility model.

[0028] In the description of the present invention, unless otherwise specified, "multiple" means two or more; the terms "center", "longitudinal", "lateral", "up", "down", "left", "right", "inside", "outside", "front end", "rear end", "head", "tail", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", "third", etc. are only used for descriptive purposes and cannot be understood as indicating or implying relative importance.

[0029] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood by specific circumstances.

[0030] like Figure 1 As shown, a solid phase extraction device includes a panel 200, a cylinder body 300, a sample rack 800 and a waste liquid tank 700, wherein the panel 200 is fixed or covered on the cylinder body 300; an opening is provided on the side wall of the cylinder body 300; a sealing member 600 is provided at the opening, and the sealing member 600 is rotatably connected or plug-connected to the cylinder body 300; the waste liquid tank 700 or the sample rack 800 is placed inside the cylinder body 300 through the opening, and one of the waste liquid tank 700 and the sample rack 800 is placed inside the cylinder body 300, and the other is placed outside the cylinder body 300; the panel 200, the cylinder body 300 and the sealing member 600 together constitute a closed cylinder chamber.

[0031] The seal 600 may be a door, the rotating part may be arranged in a vertical direction or in a horizontal direction, and the seal 600 may also be other structures as long as it can achieve a sealing effect. When in use, the seal 600 is opened, and then the waste liquid tank 700 is placed from the opening into the interior of the cylinder 300, and the seal 600 is closed for activation, sample loading and elution. After the elution is completed, the seal 600 is opened, the waste liquid tank 700 is taken out, and then the sample rack 800 is placed from the opening into the interior of the cylinder 300 for the next operation.

[0032] like Figure 1 , Figure 3 , Figure 6 As shown, as a further solution of the present invention: the waste liquid tank 700 or the sample rack 800 is slidably connected to the inner wall of the cylinder body 300 .

[0033] The waste liquid tank 700 includes a waste liquid tank bottom plate 710 and a waste liquid tank wall 720, and a waste liquid tank sliding portion 72a extending outward is provided at the upper end of the waste liquid tank wall 720. The cylinder body 300 includes a cylinder body side wall 310 and a bottom plate 320, and a side wall sliding groove 311 matching the waste liquid tank sliding portion 72a is provided on the inner side of the cylinder body side wall 310. Similarly, when the waste liquid tank sliding portion 72a is groove-shaped, a slide rail matching the waste liquid tank sliding portion 72a is provided on the inner side of the cylinder body side wall 310. At the same time, a first through hole 312 is also provided on the cylinder body side wall 310.

[0034] The sample rack 800 includes a test tube rack 830 and a fixing plate 840. When the sample rack 800 needs to be placed inside the cylinder 300, the test tube rack 830 and / or the fixing plate 840 can be inserted into the side wall slide groove 311.

[0035] like Figure 3 As shown as a further solution of the utility model: a bearing portion 620 is also provided on the sealing member 600, and the bearing portion 620 is slidably connected to the inner wall of the cylinder body 300, and the waste liquid tank 700 or the sample rack 800 is carried and transported to the interior of the cylinder body 300 through the bearing portion 620.

[0036] In some embodiments, a solid phase extraction device includes a panel 200, a cylinder body 300, a sample rack 800 and a waste liquid tank 700, wherein the panel 200 is fixed or covered on the cylinder body 300, an opening is provided on the side wall of the cylinder body 300, a sealing member 600 is provided at the opening, the sealing member 600 is rotatably connected or plug-connected to the cylinder body 300, the waste liquid tank 700 or the sample rack 800 is placed inside the cylinder body 300 through the opening, one of the waste liquid tank 700 and the sample rack 800 is placed inside the cylinder body 300, and the other is placed outside the cylinder body 300; the panel 200, the cylinder body 300 and the sealing member 600 constitute a closed cylinder chamber, the sealing member 600 is further provided with a bearing portion 620, the bearing portion 620 is slidably connected to the inner side wall of the cylinder body 300, and the waste liquid tank 700 or the sample rack 800 is carried and transported to the inside of the cylinder body 300 through the bearing portion 620.

[0037] The opening is provided on the side wall of the cylinder 300, which is helpful for conveniently taking out the waste liquid in the waste liquid tank 700 after pulling out the sealing member 600, and even after pulling out the sealing member 600, the waste liquid in the waste liquid tank 700 placed on the carrying part 620 can be directly taken out. Then the sample rack 800 is directly placed into the interior of the cylinder 300 through the opening, or the sample rack 800 is carried to the interior of the cylinder 300 through the carrying part 620. It is avoided that the panel 200 is inconveniently removed and then the waste liquid tank 700 is taken out, and then the sample rack 800 is placed from the panel 200 into the interior of the cylinder 300, which is cumbersome. At the same time, the waste liquid tank 700 and the sample rack 800 are placed into the cylinder 300 or taken out from the cylinder 300 through the opening, which can also improve the use efficiency and realize the rapid filtration of the sample liquid. At the same time, the risk of cross contamination of the interior of the cylinder 300 and the sample can also be avoided.

[0038] In order to adjust the height of the waste liquid tank 700 and the sample rack 800, a bottom plate support portion 32a is provided on the bottom plate 320. In order to ensure the tightness of the cylinder body 300, a cylinder body threshold 313 is provided at the opening. The bottom plate support portion 32a and the cylinder body threshold 313 are at the same height.

[0039] like Figure 1 As shown, as a further solution of the utility model: it also includes a valve 430, and the valve 430 is connected to the cylinder body 300.

[0040] When the sealing member 600 is in a drawer shape, a second vent hole 63a is provided on the bearing wall 630, and the second vent hole 63a corresponds to the first vent hole 312 to ensure that the cylinder body 300 is connected with the outside.

[0041] like Figure 1 As shown, as a further solution of the utility model: it also includes a pressure gauge 410, and the pressure gauge 410 is connected to the valve 430 and is arranged on the valve 430.

[0042] The valve 430 is provided with a control switch, and the valve interface 420 at the other end of the valve 430 is connected to a vacuum pump to accelerate the elution of the sample liquid.

[0043] like Figure 1 , Figure 2 As shown, as a further solution of the utility model: it also includes a plurality of purification columns 100, and the purification columns 100 are connected to the panel 200.

[0044] During activation, sample loading, and elution, the sealing member 600 is first pulled out, and the waste liquid tank 700 is slid into the cylinder body 300 through the side wall slide groove 311, and then slid into the sealing member 600. Alternatively, the waste liquid tank 700 can be directly placed on the bearing portion 620, and the waste liquid tank 700 is directly slid into the cylinder body 300 through the bearing portion 620. The waste liquid tank 700 receives the waste liquid from activation, sample loading, and elution of the purification column 100. After elution is completed, the sealing member 600 is opened, and the waste liquid tank 700 is taken out, or the waste liquid tank 700 placed on the sealing member 600 is directly slid out with the bearing portion 620. During elution, the waste liquid tank 700 is replaced by the sample rack 800, and the test glass tube is placed on the sample rack 800. The sample rack 800 slides into the cylinder body 300 through the side wall slide groove 311. The sample rack 800 can also be placed on the supporting portion 620 and slides into the cylinder body 300 with the supporting portion 620. The sample solution and the sample elution solution flow into the glass tube through the purification column 100 for elution.

[0045] like Figure 1 As shown, as a further solution of the present utility model: a control valve 10a is provided at the lower end of the purification column 100.

[0046] The control valve 10a is provided to better control the flow rate through the column. When the control valve 10a is closed, the panel 200 and the cylinder body 300 form a closed space.

[0047] like Figure 1 , Figure 2 As shown, as a further solution of the present invention: a flange 230 is provided on the panel 200 toward the cylinder body 300 .

[0048] The panel 200 includes a panel body 220 , on which a number of inlet holes 210 matching the number of the purification columns 100 are disposed, and the inlet holes 210 are used to match the purification columns 100 .

[0049] When in use, the flange 230 is sleeved on the upper end of the cylinder body 300 to improve the tightness of the cylinder body 300, which is conducive to meeting the extraction environment requirements.

[0050] like Figure 1 , Figure 2 As shown, as a further solution of the present invention: a support leg 240 is provided on the panel 200 toward the cylinder body 300 .

[0051] Providing the supporting legs 240 is beneficial to protecting the purification column 100 when the panel 200 is taken out.

[0052] like Figure 1 As shown, as a further solution of the utility model: it also includes a cylinder base 500, and the cylinder base 500 is in the shape of a box without a cover, and the lower end of the cylinder 300 is placed in the cylinder base 500.

[0053] Preferably, the cylinder base 500 and the cylinder 300 are both in the shape of a rectangular parallelepiped, and the lower end of the cylinder 300 is placed in the cylinder base 500 without looseness. The cylinder base 500 is provided to facilitate positioning of the cylinder 300 and prevent the cylinder 300 from moving.

[0054] like Figure 7 As shown, the sample rack 800 also includes two support columns 810, four fixing members 820, and the support columns 810 and the test tube rack 830 are fixed by the fixing members 820, and the test tube rack 830 and the fixing plate 840 are supported by the support columns 810 to form a shelf layer structure. The test tube rack 830 is provided with a plurality of test tube holes 83a for inserting the glass test tubes. When using the sample rack 800, the test tube rack 830 can be slidably inserted into the side wall slide groove 311, or a fixing hole 841 can be provided on the fixing plate 840, the support column 810 is inserted into the fixing hole 841, the fixing plate 840 is placed flat on the bearing part 620, and the entire sample rack 800 is slid into the cylinder body 300 along with the bearing part 620. A hand-held portion 842 is also provided on the edge of the fixing plate 840 to facilitate taking the fixing plate 840.

[0055] First embodiment

[0056] like Figure 4 As shown, the sealing member 600 includes a decorative portion 610 and a bearing portion 620. A handle 611 is also provided on the outside of the decorative portion 610 to facilitate pulling or pushing the sealing member 600. The bearing portion 620 can be a plate-like structure or a mesh structure, as long as it can bear the waste liquid tank 700. The decorative portion 610 is a plate-like structure, which, in addition to its decorative function, mainly has the function of sealing the cylinder body 300. At the same time, a sealing portion 612 made of rubber material is provided on the edge of the decorative portion 610 to improve the overall sealing of the cylinder body 300.

[0057] Second embodiment

[0058] like Figure 1 , Figure 4 , Figure 5 As shown, as a further solution of the present utility model: the sealing member 600 is a drawer.

[0059] The second embodiment is based on the first embodiment, and the sealing member 600 further includes a bearing wall 630, and the sealing member 600 composed of the decorative portion 610, the bearing portion 620 and the bearing wall 630 is in a drawer shape. The sealing member 600 is arranged in a drawer shape, which is conducive to preventing the waste liquid in the waste liquid tank 700 from splashing into the cylinder body 300, thereby contaminating the cylinder body 300.

[0060] The above description is only a preferred embodiment of the present invention and does not constitute any form of limitation to the present invention. Although the present invention has been disclosed as a preferred embodiment as above, it is not intended to limit the present invention. Any technician familiar with the profession can make some changes or modify the technical contents disclosed above into equivalent embodiments without departing from the scope of the technical solution of the present invention. However, any simple modification, equivalent change and modification made to the above embodiments based on the technical essence of the present invention without departing from the content of the technical solution of the present invention still fall within the scope of the technical solution of the present invention.

Claims

1. A solid phase extraction device, comprising a panel, a cylinder, a sample rack and a waste liquid tank, wherein the panel is fixed or covered on the cylinder, characterized in that: An opening is provided on the side wall of the cylinder body; a sealing member is provided at the opening, and the sealing member is rotatably connected or plug-connected to the cylinder body; the waste liquid tank or the sample rack is placed inside the cylinder body through the opening, and one of the waste liquid tank and the sample rack is placed inside the cylinder body, and the other is placed outside the cylinder body; the panel, the cylinder body and the sealing member together constitute a closed cylinder chamber.

2. The solid phase extraction device according to claim 1, characterized in that: The waste liquid tank or the sample rack is slidably connected to the inner side wall of the cylinder body.

3. The solid phase extraction device according to claim 1, characterized in that: The sealing member is also provided with a bearing portion, which is slidably connected to the inner wall of the cylinder body, and the waste liquid tank or the sample rack is carried and transported to the interior of the cylinder body through the bearing portion.

4. The solid phase extraction device according to claim 3, characterized in that: The sealing member is a drawer.

5. The solid phase extraction device according to claim 4, characterized in that: Also included is a valve, which is communicated with the cylinder.

6. The solid phase extraction device according to claim 5, characterized in that: It also includes a pressure gauge, which is connected to the valve and arranged on the valve.

7. The solid phase extraction device according to claim 6, characterized in that: It also includes a plurality of purification columns, which are connected to the panel.

8. The solid phase extraction device according to claim 7, characterized in that: A control valve is arranged at the lower end of the purification column.

9. The solid phase extraction device according to claim 8, characterized in that: The panel is provided with a flange facing the cylinder body.

10. The solid phase extraction device according to claim 9, characterized in that: The panel is provided with supporting legs facing the cylinder body.

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