Automatic sampler of chromatographic instrument
By designing a cleaning device in the injection system of the liquid chromatograph, the connecting rod and the first circular tube driven by the motor are used to clean the surface of the injection needle, solving the problem of residual samples and dust in the injection needle, and improving the detection accuracy.
Patent Information
- Application Number
- CN202421247026.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-03
- Publication Date
- 2025-04-18
- Estimated Expiration
- 2034-06-03
AI Technical Summary
When the injection system of existing liquid chromatographs is automatically injected, the sample may remain on the surface of the injection needle, and it is easily covered with dust when exposed, resulting in impurities doping in the sample and affecting the detection accuracy.
A chromatograph automatic sampler is designed, and a cleaning device is adopted, including a rectangular rod, a motor, a connecting rod, a first round tube, a cleaning cotton tube and a circular hole block. The connecting rod and the first round tube are driven to rotate through the motor, so that the cleaning cotton tube fits the surface of the injection needle for cleaning, and the alternating use of multiple cleaning cotton tubes can reduce residual and dust on the surface of the injection needle.
Effectively clean the residual samples and dust on the surface of the injection needle, reducing the possibility of impurities doping in the sample, improving detection accuracy, and simplifying the cleaning process.
Smart Images
Figure CN222774539U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of automatic sample injectors, in particular to an automatic sample injector for a chromatograph. Background Art
[0002] Liquid chromatographs are divided into liquid-liquid chromatography (LLC) and liquid-solid chromatography (LSC) according to whether the stationary phase is liquid or solid. Modern liquid chromatographs are composed of high-pressure infusion pumps, injection systems, temperature control systems, chromatographic columns, detectors, signal recording systems, etc. Compared with classic liquid column chromatography devices, they are more efficient, faster, and more sensitive.
[0003] The injection system in the existing liquid chromatograph usually inserts the vessel into the hole plate during automatic injection, and then connects the external hose to the feed pipe. At this time, the body drives the hole plate to rotate through the internal transmission mechanism. When the hole plate brings the vessel to the specified position, the transmission column starts and drives the injection needle to move up and down through the internal transmission mechanism, so that the injection needle is inserted into the vessel for automatic injection. However, some sample may remain on the surface of the injection needle after injection. At the same time, the injection needle is exposed to the outside and will be contaminated with some dust in the environment, which may cause the residual sample and external dust to follow the injection needle into the vessel, causing impurities to be mixed in the sample and affect the detection accuracy. Utility Model Content
[0004] The utility model aims to solve the shortcomings in the prior art and provides an automatic sample injector for chromatograph.
[0005] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a chromatograph automatic sample injector, comprising a body, a hole plate is arranged on one side of the body, a feed tube is arranged on one side of the body, a transmission column is arranged on one side of the body, a sample injection needle is arranged on one side of the transmission column, a control button is arranged on one side of the body, a cleaning device is arranged on the side of the body close to the sample injection needle, an anti-mistaken touch device is arranged on the side of the body close to the control button, the cleaning device comprises a rectangular rod, the rectangular rod is fixedly connected to the side of the body close to the transmission column, and one side of the rectangular rod is fixedly connected A circular frame is provided, a motor is provided inside the circular frame, a connecting rod is fixedly connected to the output end of the motor, a first circular tube is fixedly connected to one side of the connecting rod, a rectangular groove is provided on one side of the first circular tube, a threaded groove is provided on the inner wall of the rectangular groove, a second circular tube is slidably connected to the inner wall of the first circular tube, a cleaning cotton cylinder is fixedly connected to the inner wall of the second circular tube, a circular hole block is fixedly connected to one side of the second circular tube, the surface size and shape of the circular hole block are matched with the size and shape of the inner wall of the rectangular groove, a bolt is provided inside the circular hole block, and the surface of the bolt is threadedly connected to the inner wall of the threaded groove.
[0006] The effect achieved by the above components is as follows: by setting up the cleaning device, first manually move the second round tube, so that the second round tube drives the cleaning cotton cylinder to move, so that the second round tube drives the circular hole block to move, when the second round tube moves to the position of inserting into the interior of the first round tube, the circular hole block is stuck in the interior of the rectangular groove, so that the inner wall of the circular hole block coincides with the inner wall of the thread groove, at this time, the bolt is rotated by the tool, so that the bolt is rotated into the circular hole block and the inner position of the thread groove to fix the circular hole block, and the connection and fixation of the cleaning cotton cylinder and the first round tube are completed, and when the transmission column drives the injection needle to move up and down, the injection needle The cleaning cotton cylinder is inserted into the inside of the sample injection needle and moved up and down, so that the cleaning cotton cylinder is attached to the surface of the sample injection needle to clean the impurities and residual samples. At the same time, the motor is started to drive the connecting rod to rotate, and the connecting rod drives the first round tube to rotate. When the other first round tube and the cleaning cotton cylinder are rotated to a position below the sample injection needle, the alternating use of multiple cleaning cotton cylinders is completed, which reduces the sample residue and dust attached to the surface of the sample injection needle, resulting in the situation where impurities are mixed in the sample injected into the vessel later and affect the detection effect, and improves the cleaning effect and convenience of the sample injection needle.
[0007] Preferably, a support rod is fixedly connected to one side of the connecting rod close to the first circular tube, and the support rod is fixedly connected to the first circular tube.
[0008] The effect achieved by the above components is: by arranging the support rod, the support rod can support and reinforce the first round tube, thereby reducing the shaking of the first round tube during use.
[0009] Preferably, a circular ring is fixedly connected to the inner wall of the first circular tube, and the inner wall of the circular ring is smaller than the inner wall of the second circular tube.
[0010] The effect achieved by the above components is: by setting the circular ring, the circular ring can assist in intercepting the second circular tube inside the first circular tube, thereby reducing the shaking of the second circular tube away from the circular hole block when the second circular tube is located inside the first circular tube for use.
[0011] Preferably, an auxiliary block is fixedly connected to one side of the circular hole block, and the surface of the auxiliary block is rectangular.
[0012] The effect achieved by the above components is: by setting the auxiliary block, the auxiliary block can provide a fulcrum for the circular hole block, so that personnel can quickly move the circular hole block out of the rectangular groove by tools or manually moving the auxiliary block, thereby improving the convenience of personnel taking out the second circular tube.
[0013] Preferably, a plurality of annular cottons are fixedly connected to the inner wall of the cleaning cotton cylinder, and the plurality of annular cottons are arranged at equal distances.
[0014] The effect achieved by the above components is: by arranging the annular cotton, multiple annular cottons can fit the surface of the injection needle to scrape off the attached impurities multiple times, thereby improving the cleaning effect of the cleaning cotton tube on the injection needle.
[0015] Preferably, the anti-mistouch device comprises a rectangular frame, the rectangular frame is fixedly connected to a side of the body close to the control button, a rectangular hole is opened on one side of the rectangular frame, and a protective plate is slidably connected to the inner wall of the rectangular hole.
[0016] The effect achieved by the above components is: by setting up an anti-accidental touch device, first manually move the protective plate so that the protective plate moves left and right along the inside of the rectangular hole. When the protective plate moves to the position entering the inside of the rectangular frame, the protective plate cooperates with the rectangular frame to completely cover the internal control buttons and intercept external objects, thereby reducing the situation where people accidentally touch the control buttons when sampling, causing changes in the machine operation program to affect detection.
[0017] Preferably, a baffle is fixedly connected to one side of the protective plate, and the surface of the baffle is larger than the inner wall of the rectangular hole.
[0018] The effect achieved by the above components is: by setting the baffle, the baffle can intercept the protective plate during the movement, thereby reducing the situation where the protective plate excessively enters the rectangular frame.
[0019] Preferably, a push block is fixedly connected to one side of the protective plate, and the surface of the push block is rectangular.
[0020] The effect achieved by the above components is: by setting the push block, personnel can drive the protective plate to move quickly by manually moving the push block, thereby improving the convenience of personnel manually moving the protective plate.
[0021] Compared with the prior art, the advantages and positive effects of the utility model are:
[0022] In the utility model, impurities remaining on the surface of the injection needle can be quickly cleaned by arranging a cleaning device, and multiple cleaning cotton tubes can be used alternately, thereby reducing the situation where sample residues and dust adhere to the surface of the injection needle, resulting in impurities being mixed in the sample subsequently injected into the vessel and affecting the detection effect, thereby improving the cleaning effect and convenience of the injection needle. BRIEF DESCRIPTION OF THE DRAWINGS
[0023] Figure 1 It is a three-dimensional structural schematic diagram of the utility model;
[0024] Figure 2 It is a schematic diagram of the partial structure of the first circular tube of the utility model;
[0025] Figure 3 It is a schematic diagram of the partial structure of the second round tube of the utility model;
[0026] Figure 4 It is a schematic diagram of the local structure of the rectangular frame of the utility model.
[0027] Legend: 1. Machine body; 2. Hole plate; 3. Feed pipe; 4. Transmission column; 5. Sample injection needle; 6. Control button; 7. Cleaning device; 71. Rectangular rod; 72. Round frame; 73. Motor; 74. Connecting rod; 75. First round tube; 76. Rectangular groove; 77. Threaded groove; 78. Ring; 79. Support rod; 710. Second round tube; 711. Cleaning cotton cylinder; 712. Round hole block; 713. Bolt; 714. Auxiliary block; 715. Ring cotton; 8. Anti-accidental touch device; 81. Rectangular frame; 82. Rectangular hole; 83. Protective plate; 84. Baffle; 85. Push block. DETAILED DESCRIPTION
[0028] Reference Figure 1-3As shown, this embodiment discloses a chromatograph automatic sample injector, including a body 1, a hole plate 2 is arranged on one side of the body 1, a feed tube 3 is arranged on one side of the body 1, a transmission column 4 is arranged on one side of the body 1, a sample injection needle 5 is arranged on one side of the transmission column 4, a control button 6 is arranged on one side of the body 1, a cleaning device 7 is arranged on the side of the body 1 close to the sample injection needle 5, and an anti-mistake touch device 8 is arranged on the side of the body 1 close to the control button 6. The cleaning device 7 includes a rectangular rod 71, the rectangular rod 71 is fixedly connected to the side of the body 1 close to the transmission column 4, a round frame 72 is fixedly connected to one side of the rectangular rod 71, a motor 73 is arranged inside the round frame 72, and the motor 73 The output end is fixedly connected with a connecting rod 74, one side of the connecting rod 74 is fixedly connected with a first round tube 75, one side of the first round tube 75 is provided with a rectangular groove 76, the inner wall of the rectangular groove 76 is provided with a threaded groove 77, the inner wall of the first round tube 75 is slidably connected with a second round tube 710, the inner wall of the second round tube 710 is fixedly connected with a cleaning cotton cylinder 711, one side of the second round tube 710 is fixedly connected with a round hole block 712, the surface size and shape of the round hole block 712 are adapted to the size and shape of the inner wall of the rectangular groove 76, a bolt 713 is provided inside the round hole block 712, the surface of the bolt 713 is threadedly connected to the inner wall of the threaded groove 77, and by setting a cleaning The device 7 first manually moves the second round tube 710 so that the second round tube 710 drives the cleaning cotton cylinder 711 to move, and the second round tube 710 drives the round hole block 712 to move. When the second round tube 710 moves to the position of being inserted into the interior of the first round tube 75, the round hole block 712 is stuck in the interior of the rectangular groove 76, so that the inner wall of the round hole block 712 coincides with the inner wall of the thread groove 77. At this time, the bolt 713 is rotated by the tool so that the bolt 713 is rotated into the position of the round hole block 712 and the inner wall of the thread groove 77 to fix the round hole block 712, completing the connection and fixation of the cleaning cotton cylinder 711 and the first round tube 75. When the transmission column 4 drives the injection needle 5 to move up and down, the injection needle 5 The sample needle 5 is inserted into the cleaning cotton tube 711 and moves up and down, so that the cleaning cotton tube 711 fits the surface of the sample injection needle 5 to clean the impurities and residual samples attached thereto, and at the same time, the motor 73 is started, so that the motor 73 drives the connecting rod 74 to rotate, and the connecting rod 74 drives the first circular tube 75 to rotate. When the other first circular tube 75 and the cleaning cotton tube 711 rotate to a position below the sample injection needle 5, the alternating use of multiple cleaning cotton tubes 711 is completed, thereby reducing the sample residue and dust attached to the surface of the sample injection needle 5, which causes the sample subsequently injected into the vessel to be doped with impurities and affects the detection effect, thereby improving the cleaning effect and convenience of the sample injection needle 5.
[0029] Reference Figure 2 and Figure 3As shown, the present embodiment discloses that a support rod 79 is fixedly connected to one side of the connecting rod 74 close to the first circular tube 75, and the support rod 79 is fixedly connected to the first circular tube 75. By setting the support rod 79, the support rod 79 can support and reinforce the first circular tube 75, thereby reducing the shaking of the first circular tube 75 during use. A circular ring 78 is fixedly connected to the inner wall of the first circular tube 75, and the inner wall of the circular ring 78 is smaller than the inner wall of the second circular tube 710. By setting the circular ring 78, the circular ring 78 can assist in intercepting the second circular tube 710 inside the first circular tube 75, thereby reducing the shaking of the second circular tube 710 on the side away from the circular hole block 712 when the second circular tube 710 is located inside the first circular tube 75 for use.
[0030] Reference Figure 2 and Figure 3 As shown, the present embodiment discloses that one side of the circular hole block 712 is fixedly connected with an auxiliary block 714, and the surface of the auxiliary block 714 is rectangular. By setting the auxiliary block 714, the auxiliary block 714 can provide a fulcrum for the circular hole block 712, so that personnel can quickly move the circular hole block 712 out of the rectangular groove 76 by tools or manually moving the auxiliary block 714, thereby improving the convenience of personnel taking out the second circular tube 710, and the inner wall of the cleaning cotton tube 711 is fixedly connected with a plurality of annular cottons 715, and the plurality of annular cottons 715 are arranged at equal distances. By setting the annular cottons 715, the plurality of annular cottons 715 can fit the surface of the injection needle 5 to scrape off the attached impurities multiple times, thereby improving the cleaning effect of the cleaning cotton tube 711 on the injection needle 5.
[0031] Reference Figure 4 As shown, the present embodiment discloses an anti-mis-touch device 8 including a rectangular frame 81, which is fixedly connected to one side of the body 1 close to the control button 6, and a rectangular hole 82 is provided on one side of the rectangular frame 81, and a protective plate 83 is slidably connected to the inner wall of the rectangular hole 82. By setting the anti-mis-touch device 8, the protective plate 83 is first manually moved so that the protective plate 83 moves left and right along the inside of the rectangular hole 82. When the protective plate 83 moves to a position entering the inside of the rectangular frame 81, the protective plate 83 cooperates with the rectangular frame 81 to completely cover the internal control button 6 and intercept external objects, thereby reducing the situation where personnel accidentally touch the control button 6 during sampling, causing the running program of the body 1 to change and affect the detection.
[0032] Reference Figure 4As shown, the present embodiment discloses that one side of the protective plate 83 is fixedly connected with a baffle 84, and the surface of the baffle 84 is larger than the inner wall of the rectangular hole 82. By setting the baffle 84, the baffle 84 can intercept the protective plate 83 during the movement, thereby reducing the situation where the protective plate 83 excessively enters the rectangular frame 81. One side of the protective plate 83 is fixedly connected with a push block 85, and the surface of the push block 85 is rectangular. By setting the push block 85, a person can drive the protective plate 83 to move quickly by manually moving the push block 85, thereby improving the convenience of manually moving the protective plate 83.
[0033] Working principle: first insert the vessel into the hole plate 2, then connect the external hose to the feed pipe 3. At this time, the body 1 drives the hole plate 2 to rotate through the internal transmission mechanism. When the hole plate 2 brings the vessel to the specified position, the transmission column 4 starts and drives the injection needle 5 to move up and down through the internal transmission mechanism, so that the injection needle 5 is inserted into the vessel for automatic injection.
[0034] First, manually move the second round tube 710 so that the second round tube 710 drives the cleaning cotton cylinder 711 to move, and the second round tube 710 drives the round hole block 712 to move. When the second round tube 710 moves to the position of being inserted into the interior of the first round tube 75, the round hole block 712 is inserted into the interior of the rectangular groove 76, so that the inner wall of the round hole block 712 coincides with the inner wall of the thread groove 77. At this time, the bolt 713 is rotated by a tool so that the bolt 713 is rotated into the inner position of the round hole block 712 and the thread groove 77 to fix the round hole block 712, thereby completing the connection between the cleaning cotton cylinder 711 and the first round tube 75. When the transmission column 4 drives the injection needle 5 to move up and down, the injection needle 5 is inserted into the cleaning cotton tube 711 and moves up and down, so that the cleaning cotton tube 711 fits the surface of the injection needle 5 to clean the impurities and residual samples attached to it, thereby completing the rapid cleaning of the injection needle 5. At the same time, the motor 73 is started, so that the motor 73 drives the connecting rod 74 to rotate, and the connecting rod 74 drives the first circular tube 75 to rotate. When the other first circular tube 75 and the cleaning cotton tube 711 rotate to a position below the injection needle 5, the alternating use of multiple cleaning cotton tubes 711 is completed.
[0035] First, manually move the push block 85 so that the push block 85 drives the protective plate 83 to move, so that the protective plate 83 moves left and right along the rectangular hole 82. When the protective plate 83 moves to the position inside the rectangular frame 81, the protective plate 83 cooperates with the rectangular frame 81 to completely cover the internal control button 6 and intercept external objects, thereby preventing the control button 6 from being accidentally touched.
[0036] The above is only a preferred embodiment of the utility model, and does not limit the utility model in other forms. Any technician familiar with the profession may use the technical content disclosed above to change or modify it into an equivalent embodiment with equivalent changes and apply it to other fields. However, any simple modification, equivalent change and modification made to the above embodiment based on the technical essence of the utility model without departing from the technical solution of the utility model still belongs to the protection scope of the technical solution of the utility model. In the description of the utility model, it should be noted that unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected, or indirectly connected through an intermediate medium, or it can be the internal connection of two components. For ordinary technicians in this field, the specific meanings of the above terms in the utility model can be understood by specific circumstances.
Claims
1. A chromatograph automatic sample injector, comprising a body (1), characterized in that: A hole plate (2) is provided on one side of the machine body (1), a feed pipe (3) is provided on one side of the machine body (1), a transmission column (4) is provided on one side of the machine body (1), a sample injection needle (5) is provided on one side of the transmission column (4), a control button (6) is provided on one side of the machine body (1), a cleaning device (7) is provided on the side of the machine body (1) close to the sample injection needle (5), an anti-mistaken touch device (8) is provided on the side of the machine body (1) close to the control button (6), the cleaning device (7) comprises a rectangular rod (71), the rectangular rod (71) is fixedly connected to the side of the machine body (1) close to the transmission column (4), a round frame (72) is fixedly connected to one side of the rectangular rod (71), a motor (73) is provided inside the round frame (72), and the motor (73) The output end of the connecting rod (74) is fixedly connected to a connecting rod (74), one side of the connecting rod (74) is fixedly connected to a first circular tube (75), one side of the first circular tube (75) is provided with a rectangular groove (76), the inner wall of the rectangular groove (76) is provided with a threaded groove (77), the inner wall of the first circular tube (75) is slidably connected to a second circular tube (710), the inner wall of the second circular tube (710) is fixedly connected to a cleaning cotton cylinder (711), one side of the second circular tube (710) is fixedly connected to a circular hole block (712), the surface size and shape of the circular hole block (712) are matched to the size and shape of the inner wall of the rectangular groove (76), a bolt (713) is provided inside the circular hole block (712), and the surface of the bolt (713) is threadedly connected to the inner wall of the threaded groove (77).
2. A chromatograph automatic sample injector according to claim 1, characterized in that: A support rod (79) is fixedly connected to one side of the connecting rod (74) close to the first circular tube (75), and the support rod (79) is fixedly connected to the first circular tube (75).
3. A chromatograph automatic sample injector according to claim 2, characterized in that: A circular ring (78) is fixedly connected to the inner wall of the first circular tube (75), and the inner wall of the circular ring (78) is smaller than the inner wall of the second circular tube (710).
4. A chromatograph automatic sample injector according to claim 3, characterized in that: An auxiliary block (714) is fixedly connected to one side of the circular hole block (712); the surface of the auxiliary block (714) is rectangular.
5. A chromatograph automatic sample injector according to claim 4, characterized in that: A plurality of annular cotton balls (715) are fixedly connected to the inner wall of the cleaning cotton cylinder (711), and the plurality of annular cotton balls (715) are arranged at equal distances.
6. The chromatograph automatic sample injector according to claim 1, characterized in that: The anti-mistouch device (8) comprises a rectangular frame (81), the rectangular frame (81) being fixedly connected to a side of the machine body (1) close to the control button (6), a rectangular hole (82) being provided on one side of the rectangular frame (81), and a protective plate (83) being slidably connected to the inner wall of the rectangular hole (82).
7. A chromatograph automatic sample injector according to claim 6, characterized in that: A baffle plate (84) is fixedly connected to one side of the protection plate (83), and the surface of the baffle plate (84) is larger than the inner wall of the rectangular hole (82).
8. The chromatograph automatic sample injector according to claim 6, characterized in that: A push block (85) is fixedly connected to one side of the protective plate (83), and the surface of the push block (85) is rectangular.