Centrifugal auxiliary device for preparing cryoprecipitation blood coagulation factors

Abstract

The utility model relates to the technical field of cryoprecipitation blood coagulation factor preparation, in particular to a centrifugal auxiliary device for cryoprecipitation blood coagulation factor preparation, which comprises a casing, a first chamber arranged at the bottom in the casing, a second chamber arranged at the top of the casing, a centrifugal seat arranged in the second chamber, a driving shaft connected with the bottom of the centrifugal seat, and a driving shaft connected with the driving shaft. The bottom of the driving shaft penetrates into the first cavity and is connected with a first driving motor, the first driving motor is fixed into the first cavity through a support, and the driving shaft is rotationally connected with the machine shell. A third cavity is formed in the center of the top of the centrifugal base. When the centrifugal auxiliary device for preparing the cryoprecipitation blood coagulation factors is used, the pressing plate moves in the placing groove so as to press and fix the upper edge of a linked bag placed in the placing groove, so that the linked bag does not generate centrifugal deformation during centrifugal rotation, and the blood coagulation factors are ensured to be stably concentrated and centrifuged in the linked bag; the precipitation effect of the blood coagulation factors is improved.

Description

Technical Field

[0001] The utility model relates to the technical field of cold precipitated coagulation factor preparation, in particular to a centrifugal auxiliary device used for cold precipitated coagulation factor preparation. Background Art

[0002] Cryoprecipitate refers to plasma cold precipitate containing factor VIII and fibrinogen, which can treat patients with hemophilia or patients with hemophilia who have persistent bleeding due to lack of factor VIII and fibrinogen; it should be transfused within 6 hours after thawing, and the transfusion rate should not be lower than 200ml / h; it is suitable for children and adults with mild hemophilia A, von Willebrand disease, congenital or acquired fibrinogen deficiency and factor VIII deficiency; sometimes cryoprecipitate is also used as a replacement therapy for patients with postoperative bleeding, severe trauma and DIC.

[0003] In the process of preparing cold precipitated coagulation factors, the frozen plasma bag is first taken out, the frozen plasma bag and the connecting bag are connected by a pipeline, the frozen plasma bag is placed in an upper water tank, the connecting bag is placed in a lower water tank, the pipeline is placed in a siphon mechanism, and after the frozen plasma bag is melted, the siphon mechanism performs siphoning to complete the drainage of the plasma in the connecting bag, the siphon mechanism is reversed, the drained plasma is poured back into the plasma bag, and finally the connecting bag is placed in a centrifuge for centrifugation, and the supernatant is separated to obtain a cold precipitate mixture.

[0004] When using a centrifuge to centrifuge the linked bag, since the linked bag itself is made of plastic, when it is placed in the centrifuge, it is easy to collapse in the centrifuge due to its soft texture and the placement of the linked bag in the centrifuge will also be unstable. This also causes the coagulation factors to be unable to quickly gather and concentrate due to the shaking of the linked bag during centrifugation, thereby affecting the centrifugal efficiency. Utility Model Content

[0005] The purpose of the utility model is to solve the above-mentioned shortcomings in the prior art and to propose a centrifugal auxiliary device for preparing cold precipitated coagulation factors.

[0006] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a centrifugal auxiliary device for preparing cold precipitated coagulation factors is designed, comprising a casing, a first chamber is arranged at the bottom of the casing, a second chamber is opened at the top of the casing, a centrifugal seat is arranged in the second chamber, a driving shaft is connected to the bottom of the centrifugal seat, the bottom of the driving shaft passes through the first chamber and is connected to a first driving motor, the first driving motor is fixed in the first chamber by a bracket, and the driving shaft is rotatably connected to the casing;

[0007] A third chamber is provided at the center of the top of the centrifugal seat, a first bevel gear is arranged in the third chamber, a connecting pipe is coaxially mounted on the first bevel gear, a second drive motor is mounted at the bottom of the connecting pipe, and the second drive motor is fixed in the third chamber through a bracket;

[0008] A plurality of placement grooves are arranged at intervals along the top edge of the centrifugal seat, a pressure plate is arranged on the side of the placement groove close to the connecting pipe, a screw rod is installed in the middle of the pressure plate, the screw rod passes through the third chamber through a nut fixed on the side wall of the placement groove, and a spline groove is coaxially arranged on the end of the screw rod, a spline shaft is arranged in the spline groove, and a second bevel gear is coaxially connected to the other end of the spline shaft, and the second bevel gear is meshed with the first bevel gear.

[0009] Preferably, a connecting shaft is disposed in the top of the connecting tube, the connecting shaft is rotatably mounted in the connecting tube, and the top of the connecting shaft is fixed on a fixing plate, and the fixing plate is fixed to the top of the third chamber;

[0010] A plurality of supporting shafts are arranged on the side of the connecting shaft, one end of the supporting shaft is coaxially fixed on the second bevel gear, and the other end of the supporting shaft is rotatably mounted on the connecting shaft.

[0011] Preferably, at least one guide shaft is installed on one side of each pressing plate close to the screw rod, the guide shaft is parallel to the screw rod, and the other end of the guide shaft slides through the side wall of the placement groove.

[0012] Preferably, an annular slide rail is arranged at the bottom of the second chamber, the slide rail is arranged coaxially with the drive shaft, and at least two spaced-apart slide blocks are installed on the slide rail, and the slide block is fixed to the bottom of the centrifugal seat.

[0013] Preferably, a top cover corresponding to the top of the second chamber is hinged on one side of the top of the casing, and the other side of the top cover is connected to the casing via a lock.

[0014] Preferably, a control box is provided on a side of the housing away from the top cover, a controller is provided in the control box, and the controller is connected to the first drive motor and the second drive motor respectively through wires;

[0015] A display and control buttons are installed on the outer wall of the control box, and the display and control buttons are connected to the controller through wires.

[0016] Preferably, anti-slip pads are installed at the bottom corners of the casing.

[0017] The design scheme proposed by the utility model has the following beneficial effects during application:

[0018] 1. The centrifugal auxiliary device for preparing cold precipitated coagulation factors allows the pressing plate to be pressed against the inner wall of the placing groove through the movement of the pressing plate in the placing groove, so as to press and fix the upper edge of the connecting bag placed in the placing groove, so that the connecting bag will not shake during centrifugal rotation, thereby ensuring stable centrifugation of the coagulation factors in the connecting bag and improving the preparation effect of cold precipitated coagulation factors.

[0019] 2. The centrifugal auxiliary device for preparing cold precipitated coagulation factors uses the transmission of bevel gears to allow the operation of the second drive motor to simultaneously control multiple pressing plates, making the placement and fixation of the linked bag in the placement slot more convenient and quick. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 The structure of the utility model is shown in FIG. Figure 1 ;

[0021] Figure 2 The structure of the utility model is shown in FIG. Figure 2 ;

[0022] Figure 3 This is a diagram showing the internal structure of the second chamber of the utility model;

[0023] Figure 4 It is a top view of the utility model;

[0024] Figure 5 It is a cross-sectional front view of the utility model;

[0025] Figure 6 It is an enlarged view of point A of the present utility model.

[0026] In the figure: 1, casing; 2, first chamber; 3, first drive motor; 4, second chamber; 5, centrifugal seat; 6, drive shaft; 7, slide rail; 8, slider; 9, placement groove; 10, third chamber; 11, second drive motor; 12, connecting pipe; 13, first bevel gear; 14, connecting shaft; 15, supporting shaft; 16, second bevel gear; 17, spline shaft; 18, screw rod; 19, spline groove; 20, pressure plate; 21, guide shaft; 22, top cover; 23, fixing plate; 24, control box; 25, display; 26, control button. DETAILED DESCRIPTION

[0027] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0028] Reference Figure 1-Figure 6A centrifugal auxiliary device for preparing cold precipitated coagulation factors includes a casing 1. Anti-skid pads are installed at the bottom corners of the casing 1. After the casing 1 is placed on an operating table, it can prevent slipping during the operation of the centrifugal auxiliary device, thereby improving the stability of the casing 1 placed on the operating table.

[0029] like Figure 5 As shown, a first chamber 2 is provided at the bottom of the casing 1, a second chamber 4 is opened at the top of the casing 1, a centrifugal seat 5 is provided in the second chamber 4, a driving shaft 6 is connected to the bottom of the centrifugal seat 5, the bottom of the driving shaft 6 passes through the first chamber 2 and is connected to a first driving motor 3, the first driving motor 3 is fixed in the first chamber 2 by a bracket, and the driving shaft 6 is rotatably connected to the casing 1, and the first driving motor 3 provides power for the rotation of the centrifugal seat 5.

[0030] Furthermore, in order to improve the support of the drive shaft 6 for the centrifugal seat 5 and the stability of the centrifugal seat 5 during rotation, an annular slide rail 7 is arranged at the bottom of the second chamber 4. The slide rail 7 is coaxially arranged with the drive shaft 6, and at least two spaced sliders 8 are installed on the slide rail 7. The slider 8 is fixed to the bottom of the centrifugal seat 5 to provide limited support for the rotation of the centrifugal seat 5, which not only guides the rotation of the centrifugal seat 5, but also allows the slider 8 to share the gravity of the centrifugal seat 5 acting on the drive shaft 6, so that the resistance on the drive shaft 6 is reduced, making it more labor-saving to rotate.

[0031] A third chamber 10 is provided at the top center of the centrifugal seat 5, a first bevel gear 13 is provided in the third chamber 10, a connecting pipe 12 is coaxially mounted on the first bevel gear 13, a second drive motor 11 is mounted at the bottom of the connecting pipe 12, the second drive motor 11 is fixed in the third chamber 10 through a bracket, and the second drive motor 11 provides power for the rotation of the first bevel gear 13.

[0032] like Figure 5 and Figure 6As shown, a plurality of placement grooves 9 are arranged at intervals along the top edge of the centrifugal seat 5, a pressure plate 20 is arranged on one side of the placement groove 9 close to the connecting pipe 12, a screw rod 18 is installed in the middle of the pressure plate 20, the screw rod 18 passes through the third chamber 10 through a nut fixed on the side wall of the placement groove 9, and a spline groove 19 is coaxially opened on the end of the screw rod 18, a spline shaft 17 is arranged in the spline groove 19, and it is ensured that the spline shaft 17 can stably drive the screw rod 18 to rotate after the rotation, and is not affected by the threaded connection between the screw rod 18 and the nut; at the other end of the spline shaft 17, a spline groove 19 is coaxially opened on the end of the screw rod 18, and a spline shaft 17 is arranged in the spline groove 19, so as to ensure that the spline shaft 17 can stably drive the screw rod 18 to rotate without being affected by the threaded connection between the screw rod 18 and the nut; The shaft is connected to a second bevel gear 16, which meshes with the first bevel gear 13. After the connection bag containing the coagulation factors is placed in the placement groove 9, the first bevel gear 13 will drive the second bevel gear 16 to rotate together, so that the screw rod 18 will also rotate with the spline shaft 17. At this time, as the screw rod 18 rotates, the pressure plate 20 will be driven to move in the placement groove 9, so that the upper edge of the connection bag can be pressed against the inner wall of the placement groove 9, and then the connection bag can be fixed, so that the connection bag can be more stable during centrifugation, and the coagulation factors will not be able to be quickly concentrated and precipitated due to the shape and other problems.

[0033] In order to improve the stability of the second bevel gear 16, a connecting shaft 14 is arranged at the top of the connecting tube 12, the connecting shaft 14 is rotatably installed in the connecting tube 12, and the top of the connecting shaft 14 is fixed on the fixing plate 23, and the fixing plate 23 is fixed to the top of the third chamber 10; a plurality of supporting shafts 15 are arranged on the side of the connecting shaft 14, one end of the supporting shaft 15 is coaxially fixed on the second bevel gear 16, and the other end of the supporting shaft 15 is rotatably installed on the connecting shaft 14, while ensuring the normal rotation of the second bevel gear 16, the spline shaft 17 is prevented from accidentally sliding in the spline groove 19, thereby causing the second bevel gear 16 to disengage from the first bevel gear 13, and providing support for the second bevel gear 16, so as to fix the second bevel gear 16 and ensure the full engagement between the second bevel gear 16 and the first bevel gear 13.

[0034] Furthermore, at least one guide shaft 21 is installed on one side of each pressing plate 20 close to the screw rod 18. The guide shaft 21 is parallel to the screw rod 18, and the other end of the guide shaft 21 slides through the side wall of the placement groove 9 to provide a guide for the movement of the pressing plate 20 in the placement groove 9, thereby improving the stability of the pressing plate 20 during movement.

[0035] It should be noted that if Figure 1 As shown, a top cover 22 corresponding to the top of the second chamber 4 is hinged on one side of the top of the casing 1, and the other side of the top cover 22 is connected to the casing 1 through a lock. When centrifuging, the top cover 22 can be covered on the top of the casing 1 to close the placement slot 9.

[0036] like Figure 1As shown, a control box 24 is arranged on the side of the casing 1 away from the top cover 22, and a controller is arranged in the control box 24. The controller is connected to the first drive motor 3 and the second drive motor 11 respectively through wires. A display 25 and control buttons 26 are installed on the outer wall of the control box 24. The display 25 and the control buttons 26 are connected to the controller through wires. In actual use, the controller is one of a PLC logic controller, a control mainboard, and a control host.

[0037] Specifically, when in use, after placing the connecting bag in the placement groove 9, the upper edge of the connecting bag can be straightened upwards, so that the pressing plate 20 can be conveniently pressed and fixed to the connecting bag. After the connecting bag is fixed by the pressing plate 20, the top cover 22 can be covered and the first drive motor 3 can be turned on to start the centrifugal operation. After the centrifugation time is up, the top cover 22 can be opened to control the pressing plate 20 to move away from the connecting bag, and finally the connecting bag can be taken out to obtain the cold precipitated coagulation factor.

[0038] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes within the technical scope disclosed by the present invention according to the technical scheme and the utility model concept of the present invention, which should be covered by the protection scope of the present invention.

Claims

1. A centrifugal auxiliary device for preparing cryoprecipitated coagulation factors, characterized in that: The invention comprises a casing (1), a first chamber (2) is arranged at the bottom of the casing (1), a second chamber (4) is opened at the top of the casing (1), a centrifugal seat (5) is arranged in the second chamber (4), a driving shaft (6) is connected to the bottom of the centrifugal seat (5), the bottom of the driving shaft (6) passes through the first chamber (2) and is connected to a first driving motor (3), the first driving motor (3) is fixed in the first chamber (2) by a bracket, and the driving shaft (6) is rotatably connected to the casing (1); A third chamber (10) is provided at the center of the top of the centrifugal seat (5), a first bevel gear (13) is arranged in the third chamber (10), a connecting pipe (12) is coaxially mounted on the first bevel gear (13), a second drive motor (11) is mounted at the bottom of the connecting pipe (12), and the second drive motor (11) is fixed in the third chamber (10) via a bracket; A plurality of placement grooves (9) are arranged at intervals along the top edge of the centrifugal seat (5). A pressure plate (20) is arranged on one side of the placement groove (9) close to the connecting pipe (12). A screw rod (18) is installed in the middle of the pressure plate (20). The screw rod (18) passes through the third chamber (10) through a nut fixed on the side wall of the placement groove (9). A spline groove (19) is coaxially arranged on the end of the screw rod (18). A spline shaft (17) is arranged in the spline groove (19). A second bevel gear (16) is coaxially connected to the other end of the spline shaft (17). The second bevel gear (16) is meshed with the first bevel gear (13).

2. A centrifugal auxiliary device for preparing cryoprecipitated coagulation factors according to claim 1, characterized in that: A connecting shaft (14) is disposed at the top of the connecting tube (12). The connecting shaft (14) is rotatably mounted in the connecting tube (12), and the top of the connecting shaft (14) is fixed on a fixing plate (23). The fixing plate (23) is fixed to the top of the third chamber (10). A plurality of support shafts (15) are arranged on the side of the connecting shaft (14); one end of the support shaft (15) is coaxially fixed on the second bevel gear (16), and the other end of the support shaft (15) is rotatably mounted on the connecting shaft (14).

3. A centrifugal auxiliary device for preparing cryoprecipitated coagulation factors according to claim 1, characterized in that: At least one guide shaft (21) is installed on one side of each pressing plate (20) close to the screw rod (18). The guide shaft (21) is parallel to the screw rod (18), and the other end of the guide shaft (21) slides through the side wall of the placement groove (9).

4. A centrifugal auxiliary device for preparing cryoprecipitated coagulation factors according to claim 1, characterized in that: An annular slide rail (7) is arranged at the bottom of the second chamber (4). The slide rail (7) is coaxially arranged with the drive shaft (6), and at least two slide blocks (8) arranged at intervals are installed on the slide rail (7). The slide blocks (8) are fixed to the bottom of the centrifugal seat (5).

5. A centrifugal auxiliary device for preparing cryoprecipitated coagulation factors according to claim 1, characterized in that: A top cover (22) corresponding to the top of the second chamber (4) is hingedly connected to one side of the top of the casing (1), and the other side of the top cover (22) is connected to the casing (1) via a lock.

6. A centrifugal auxiliary device for preparing cryoprecipitated coagulation factors according to claim 5, characterized in that: A control box (24) is arranged on a side of the housing (1) away from the top cover (22), and a controller is arranged in the control box (24), and the controller is connected to the first drive motor (3) and the second drive motor (11) respectively through wires; A display (25) and a control button (26) are installed on the outer wall of the control box (24), and the display (25) and the control button (26) are connected to the controller through wires.

7. A centrifugal auxiliary device for preparing cryoprecipitated coagulation factors according to claim 1, characterized in that: Anti-skid pads are installed at the bottom corners of the casing (1).

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