Sericin protein dialysis filtering device

Abstract

The utility model provides a sericin protein dialysis filtering device, which relates to the technical field of sericin protein dialysis, and comprises a box body, a dialysis membrane is fixedly connected in the box body, a filtering structure is arranged on the box body, the filtering structure mainly comprises a filtering plate, the filtering plate is arranged on the box body, and the filtering plate is arranged on the box body. Four L-shaped blocks are fixedly connected to the filter plate, a pull rod is jointly and fixedly connected to the two L-shaped blocks, limiting columns are fixedly connected to the L-shaped blocks, four limiting grooves are formed in the box body, the limiting columns are matched with the limiting grooves in size, clamping grooves are formed in the inner walls of the two sides of the box body respectively, and the clamping grooves are matched with the limiting columns in size. Two clamping blocks are fixedly connected to the filtering plate, a first motor is fixedly connected to the box body, and the problem that due to the fact that impurities are contained in a sericin solution, macromolecular impurities are easily intercepted and mixed with sericin in the dialysis process, and the purity of the sericin is reduced is solved.

Description

Technical Field

[0001] The utility model relates to the technical field of sericin dialysis, and in particular to a sericin dialysis filtration device. Background Art

[0002] The diafiltration device of sericin is a key equipment used to remove small molecule impurities, salts, undissolved residues or adjust the molecular weight distribution from its solution. Diafiltration is often used in the protein purification process to ensure the purity and biological activity of the final product.

[0003] When using the current sericin dialysis filtration device, the staff often finds that the current sericin solution is generally filtered directly through the dialysis membrane, which will intercept large molecules such as sericin and allow small molecule solvents and salts to pass through. Since the sericin solution contains impurities, the large molecular impurities are easily intercepted and mixed with the sericin during the dialysis process, resulting in a reduction in the purity of the sericin. Utility Model Content

[0004] The utility model aims to solve the shortcomings of the prior art and proposes a sericin dialysis filtration device.

[0005] In order to achieve the above-mentioned purpose, the utility model adopts the following technical scheme: a sericin dialysis filtration device, comprising a box body, a dialysis membrane is fixedly connected to the box body, a filtration structure is arranged on the box body, the filtration structure is mainly composed of a filter plate, the filter plate is arranged on the box body, four L-shaped blocks are fixedly connected to the filter plate, and a pull rod is commonly fixedly connected to two of the L-shaped blocks.

[0006] The effect achieved by the above components is: the staff holds two pull rods to make the L-shaped block stuck on the side wall of the box, and then installs the filter plate in the box. When the sericin solution is injected into the box for dialysis, it will first pass through the filter plate. The filter plate will intercept impurities larger than the sericin molecules, making the sericin purity higher, thereby avoiding the situation where the sericin solution contains impurities, and the large molecular impurities are easily intercepted and mixed with the sericin during the dialysis process, thereby reducing the purity of the sericin.

[0007] Preferably, a limiting column is fixedly connected to the L-shaped block, four limiting grooves are formed on the box body, and the limiting column is matched in size to the limiting grooves.

[0008] The effect achieved by the above components is: the limiting pillars are clamped into the corresponding limiting grooves, so that the position of the filter plate is more stable.

[0009] Preferably, card slots are respectively provided on the inner walls on both sides of the box body, and two card blocks are fixedly connected to the filter plate.

[0010] The effect achieved by the above components is: the two clamping blocks are respectively clamped into the corresponding clamping slots, thereby further improving the stability of the filter plate position.

[0011] Preferably, a first motor is fixedly connected to the box body, and an agitator is fixedly connected to the output shaft of the first motor.

[0012] The effects achieved by the above components are: starting the first motor, the output shaft of the first motor drives the stirrer to rotate, and the sericin solution after preliminary filtration can be stirred to improve the dialysis effect.

[0013] Preferably, a discharge structure is provided on the box body, and the discharge structure is mainly composed of a through slot, and the through slot is opened on the box body, and a baffle is slidably connected in the through slot.

[0014] The above components have the following effects: during the dialysis process, the baffle is slid downward, and after the dialysis is completed, the baffle is slid upward, so that the dialyzed sericin can be easily taken out.

[0015] Preferably, a slide groove is provided on the box body, a sliding block is slidably connected in the slide groove, and the sliding block is fixedly connected to the baffle.

[0016] The effect achieved by the above components is that the staff can slide the baffle through the slider.

[0017] Preferably, sliding grooves are respectively provided on both sides of the box body, and push plates are slidably connected to the two sliding grooves. Fixed plates are respectively fixedly connected to the inner walls on both sides of the box body, and a collection frame is commonly provided on the two fixed plates.

[0018] The effect achieved by the above components is: after the dialysis is completed, the sliding push plate pushes the dialyzed sericin into the collection frame, and then the baffle is opened and the collection frame is taken out to facilitate the removal of the sericin, making the operation more convenient.

[0019] Preferably, a threaded rod is rotatably connected in the sliding groove, the threaded rod is threadedly connected to the push plate, a second motor is fixedly connected to the box body, and an output shaft of the second motor is fixedly connected to the threaded rod.

[0020] The effect achieved by the above components is: the second motor is started, and the output shaft of the second motor drives the threaded rod to rotate. Since the push plate slides in a limited position in the sliding groove, rotating the threaded rod can drive the push plate to slide, further improving the convenience of operation.

[0021] Compared with the prior art, the advantages and positive effects of the present invention are that, in the present invention, by setting a filtering structure, a staff member holds two pull rods to make the L-shaped block stuck on the side wall of the box, and then installs the filter plate in the box. When the sericin solution is injected into the box for dialysis, it will first pass through the filter plate, and the filter plate will intercept impurities larger than the sericin molecule, so that the sericin purity is higher, and the limiting column is inserted into the corresponding limiting groove to make the position of the filter plate more stable, and the two blocks are respectively inserted into the corresponding slots to further improve the stability of the position of the filter plate, and the first motor is started. The output shaft of the first motor drives the stirrer to rotate, and the sericin solution after the preliminary filtration can be stirred to improve the dialysis effect, thereby avoiding the situation that due to the impurities contained in the sericin solution, the large molecular impurities are easily intercepted and mixed with the sericin during the dialysis process, which leads to a reduction in the purity of the sericin. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 The utility model provides a three-dimensional structural schematic diagram of a sericin dialysis filtration device;

[0023] Figure 2 This is a three-dimensional structural schematic diagram of another perspective of a sericin dialysis filtration device proposed by the utility model;

[0024] Figure 3 This is a partial schematic diagram of a filtration structure of a sericin dialysis filtration device proposed in the utility model;

[0025] Figure 4 The utility model proposes a sericin dialysis filtration device Figure 3 Enlarged view of part A.

[0026] Legend: 1. Box body; 2. Dialysis membrane; 3. Filtration structure; 31. Filter plate; 32. L-shaped block; 33. Limiting column; 34. Limiting groove; 35. Slot; 36. Block; 37. Pull rod; 38. First motor; 39. Agitator; 4. Discharging structure; 41. Through groove; 42. Baffle; 43. Slide groove; 44. Sliding block; 45. Sliding groove; 46. Push plate; 47. Threaded rod; 48. Second motor; 49. Collection frame; 410. Fixed plate. DETAILED DESCRIPTION

[0027] Embodiment 1, as Figure 1 and Figure 3 As shown, a sericin dialysis filtration device comprises a housing 1 in which a dialysis membrane 2 is fixedly connected.

[0028] Reference Figure 2 and Figure 3The housing 1 is provided with a filter structure 3, which is mainly composed of a filter plate 31. The filter plate 31 is provided on the housing 1. Four L-shaped blocks 32 are fixedly connected to the filter plate 31. Two L-shaped blocks 32 are commonly fixedly connected with a pull rod 37. The staff holds the two pull rods 37 to make the L-shaped blocks 32 stuck on the side wall of the housing 1, and then installs the filter plate 31 in the housing 1. When the sericin solution is injected into the housing 1 for dialysis, it will first pass through the filter plate 31. The filter plate 31 will intercept impurities larger than sericin molecules, so that the sericin purity is higher, thereby avoiding the situation that the sericin solution contains impurities, and the large molecular impurities are easily intercepted and mixed with the sericin during the dialysis process, which leads to the reduction of the purity of the sericin. The L-shaped block 32 is fixedly connected to a limiting column 33, and the box body 1 is provided with four limiting grooves 34. The limiting column 33 is adapted to the limiting groove 34 in size. The limiting column 33 is inserted into the corresponding limiting groove 34 to make the position of the filter plate 31 more stable. The inner walls on both sides of the box body 1 are respectively provided with a clamping groove 35. The filter plate 31 is fixedly connected to two clamping blocks 36. The two clamping blocks 36 are respectively inserted into the corresponding clamping grooves 35 to further improve the stability of the position of the filter plate 31. The box body 1 is fixedly connected to a first motor 38, and the output shaft of the first motor 38 is fixedly connected to a stirrer 39. When the first motor 38 is started, the output shaft of the first motor 38 drives the stirrer 39 to rotate, so as to stir the sericin solution after preliminary filtration to improve the dialysis effect.

[0029] Reference Figures 1 to 4 The box body 1 is provided with a discharging structure 4, which is mainly composed of a through groove 41. The through groove 41 is provided on the box body 1, and a baffle 42 is slidably connected in the through groove 41. The baffle 42 is slid downward during the dialysis process, and the baffle 42 is slid upward after the dialysis is completed, so that the dialyzed sericin can be conveniently taken out. A sliding groove 43 is provided on the box body 1, and a slider 44 is slidably connected in the sliding groove 43. The slider 44 is fixedly connected to the baffle 42, and the staff can slide the baffle 42 through the slider 44. Sliding grooves 45 are respectively provided on both sides of the box body 1, and a push plate 46 is slidably connected in the two sliding grooves 45. Fixed plates 410 are respectively fixedly connected to the inner walls of both sides of the box body 1, and the two fixed plates 410 A collecting frame 49 is provided on the box body 1. After dialysis is completed, the sliding push plate 46 pushes the dialyzed sericin into the collecting frame 49, and then the baffle 42 is opened. The collecting frame 49 can be taken out to facilitate the removal of the sericin, making the operation more convenient. A threaded rod 47 is rotatably connected in the sliding groove 45, and the threaded rod 47 is threadedly connected to the push plate 46. A second motor 48 is fixedly connected to the box body 1, and the output shaft of the second motor 48 is fixedly connected to the threaded rod 47. When the second motor 48 is started, the output shaft of the second motor 48 drives the threaded rod 47 to rotate. Since the push plate 46 slides within a limited position in the sliding groove 45, rotating the threaded rod 47 can drive the push plate 46 to slide, further improving the convenience of operation.

[0030] Working principle: the staff holds two pull rods 37 to make the L-shaped block 32 stuck on the side wall of the box 1, and then installs the filter plate 31 in the box 1. When the sericin solution is injected into the box 1 for dialysis, it will first pass through the filter plate 31. The filter plate 31 will intercept impurities larger than the sericin molecules, so that the sericin purity is higher, thereby avoiding the situation that the sericin solution contains impurities, and the large molecular impurities are easily intercepted and mixed with the sericin during the dialysis process, which leads to the reduction of the purity of the sericin. The limiting column 33 is inserted into the corresponding limiting groove 34 to make the position of the filter plate 31 more stable, and the two blocking blocks 36 are respectively inserted into the corresponding blocking grooves 35 to further improve the stability of the position of the filter plate 31. The first motor 38 is started, and the first motor 38 is turned on. The output shaft of the machine 38 drives the stirrer 39 to rotate, and the sericin solution after preliminary filtration can be stirred to improve the dialysis effect. During the dialysis process, the baffle 42 is slid downward, and after the dialysis is completed, the baffle 42 is slid upward to facilitate the removal of the dialyzed sericin. The staff can slide the baffle 42 through the slider 44. After the dialysis is completed, the sliding push plate 46 pushes the dialyzed sericin into the collection frame 49, and then the baffle 42 is opened. The collection frame 49 can be taken out to facilitate the removal of the sericin, making the operation more convenient. The second motor 48 is started, and the output shaft of the second motor 48 drives the threaded rod 47 to rotate. Since the push plate 46 slides in the sliding groove 45, the rotation of the threaded rod 47 can drive the push plate 46 to slide, further improving the convenience of operation.

[0031] The above is only a preferred embodiment of the utility model, and does not limit the utility model in other forms. Any technician familiar with the profession may use the technical content disclosed above to change or modify it into an equivalent embodiment with equivalent changes and apply it to other fields. However, any simple modification, equivalent change and modification made to the above embodiment based on the technical essence of the utility model without departing from the technical solution of the utility model still belongs to the protection scope of the technical solution of the utility model. In the description of the utility model, it should be noted that unless otherwise clearly specified and limited, the terms "installation", "connection" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected, or indirectly connected through an intermediate medium, or it can be the internal connection of two components. For ordinary technicians in this field, the specific meanings of the above terms in the utility model can be understood by specific circumstances.

Claims

1. A sericin dialysis filtration device, comprising a housing (1), characterized in that: A dialysis membrane (2) is fixedly connected to the housing (1), a filtering structure (3) is arranged on the housing (1), the filtering structure (3) mainly comprises a filtering plate (31), the filtering plate (31) is arranged on the housing (1), four L-shaped blocks (32) are fixedly connected to the filtering plate (31), and a pull rod (37) is fixedly connected to two of the L-shaped blocks (32).

2. The sericin dialysis filtration device according to claim 1, characterized in that: The L-shaped block (32) is fixedly connected to a limiting column (33), the box body (1) is provided with four limiting grooves (34), and the limiting column (33) and the limiting grooves (34) are matched in size.

3. The sericin dialysis filtration device according to claim 2, characterized in that: The inner walls on both sides of the box body (1) are respectively provided with card slots (35), and the filter plate (31) is fixedly connected with two card blocks (36).

4. The sericin dialysis filtration device according to claim 3, characterized in that: A first motor (38) is fixedly connected to the box body (1), and a stirrer (39) is fixedly connected to the output shaft of the first motor (38).

5. The sericin dialysis filtration device according to claim 4, characterized in that: The box body (1) is provided with a discharge structure (4), the discharge structure (4) mainly consisting of a through slot (41), the through slot (41) being opened on the box body (1), and a baffle (42) being slidably connected in the through slot (41).

6. The sericin dialysis filtration device according to claim 5, characterized in that: The box body (1) is provided with a slide groove (43), a sliding block (44) is slidably connected in the slide groove (43), and the sliding block (44) is fixedly connected to the baffle (42).

7. The sericin dialysis filtration device according to claim 6, characterized in that: Sliding grooves (45) are respectively provided on both sides of the box body (1), and a push plate (46) is slidably connected to the two sliding grooves (45). Fixed plates (410) are respectively fixedly connected to the inner walls on both sides of the box body (1), and a collection frame (49) is commonly provided on the two fixed plates (410).

8. The sericin dialysis filtration device according to claim 7, characterized in that: A threaded rod (47) is rotatably connected in the sliding groove (45), the threaded rod (47) is threadedly connected to the push plate (46), a second motor (48) is fixedly connected to the box body (1), and an output shaft of the second motor (48) is fixedly connected to the threaded rod (47).

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