Fecal sample detection device

Abstract

The utility model relates to an excrement sample detection device. A first chamber and a second chamber which are mutually independent are formed in a shell of the excrement sample detection device; the partition layer is arranged in the second cavity and divides the second cavity into a positive pressure cavity close to the top and a liquid storage cavity close to the bottom, and a through hole is formed in the partition layer; the sealing piece covers the bottom of the liquid storage cavity in a sealing mode. The sampling rod is detachably inserted into the second cavity from the top of the shell, the sampling rod comprises a pinching handle, a sampling rod and a sealing assembly, and the sampling rod extends into the liquid storage cavity from the positive pressure cavity through the through hole; the pinching handle is slidably and hermetically embedded in the top of the second cavity and used for driving the sampling rod and the sealing assembly, the sampling rod can be driven by the pinching handle to pierce the sealing piece, and the sealing assembly can be driven by the sampling rod to abut against or be separated from the hole wall of the through hole; the base covers the bottom of the shell, a liquid passing cavity is formed in the base, the liquid passing cavity is separated from the second cavity through a sealing piece, and the liquid passing cavity is communicated with the first cavity.

Description

Technical Field

[0001] The utility model relates to the field of medical technology, in particular to a stool sample detection device. Background Art

[0002] Immunochromatography mainly uses the principle of immune binding reaction to detect whether the analyte is present in the sample. The fundamental basis of this detection is based on the specific binding properties between immune molecules.

[0003] Stool testing can be used for auxiliary diagnosis of various diseases, such as: gastrointestinal bleeding can be caused by various diseases. By detecting hemoglobin or transferrin in the stool, it can be determined whether the subject has gastrointestinal bleeding; Helicobacter pylori is a Gram-negative Helicobacter that parasitizes the human gastric mucosa and is related to the occurrence of various gastrointestinal diseases such as gastric cancer and gastric ulcers. By detecting Helicobacter pylori-related antigens in the stool, it can be determined whether the subject is infected with Helicobacter pylori; rotavirus, adenovirus and norovirus are common pathogens that cause viral gastroenteritis in children, often causing diarrhea in children. By detecting rotavirus, adenovirus and norovirus-related antigens in the stool, it can be determined whether the subject is infected with rotavirus, adenovirus and norovirus.

[0004] At present, most stool tests follow the following process: the hospital prescribes a stool test, the examinee collects the stool, and then hands the collection tube containing the stool to the medical staff for testing. Patients need to use stool tests to screen for gastrointestinal diseases and identify pathogens, which requires a lot of time in the hospital. In addition, the examinee does not always have the urge to defecate, resulting in low compliance with stool tests, high abandonment rates, and delayed treatment for patients.

[0005] Most of the instant diagnostic stool test reagents (immunochromatography) on the market have complicated testing steps. There are many types of stool sample collection and testing devices, but most stool testing products have certain defects. Some of the testing devices use sampling rods and other structures to collect a certain amount of samples, and then send the collected samples into a collection tube filled with a diluent. After the stool sample and the diluent are fully mixed by shaking and other methods, the diluent with the sample is dripped onto the test card. The operation steps are many and the time is long. During the test, the stool sample will come into contact with the air. If it is a pathogen test for pathogenic bacteria or viruses, it is easy to cause secondary contamination. Secondly, during the sample addition process, the sample mixed with feces in the collection tube is also easy to leak onto the hands. If it is not handled in time or not cleaned properly, the pathogen is likely to be transmitted through the feces-oral route. Another part of the testing device collects the sample with a sampling rod and directly puts it into the sample diluent. After fully mixing, the channel between the sample diluent and the test strip is opened by a limit device or other means to complete the test. This method still has problems such as complicated operating steps.

[0006] The problems with these two common detection methods are: the detection devices mentioned above are mostly split structures, and sampling, sample addition and detection are often completed in two or more steps, which poses a high risk of sample contamination. Although there are already related technologies to deal with such problems, there are still certain defects in these technologies. For example, some integrated feces sampling and detection devices require the independent limit block to be removed during use before the sampling rod can be moved to complete the sampling. However, there is a risk that the user will have difficulty correctly removing the independent limit block during use, resulting in the inability to complete the detection. The device described in the utility model can complete the detection without removing the limit component, further reducing the user's learning cost and making the detection process simpler and faster.

[0007] BACKGROUND OF THE PRESENT INVENTION The above information disclosed is only used to understand the background of the concept of the present invention and may contain information that does not constitute prior art. Utility Model Content

[0008] Based on this, it is necessary to provide a stool sample detection device to address the above problems.

[0009] A stool sample detection device, comprising:

[0010] A shell, wherein a first chamber and a second chamber that are independent of each other are formed in the shell, and the first chamber and the second chamber both penetrate the top and the bottom of the shell along the height direction of the shell;

[0011] a partition layer, the partition layer being arranged in the second chamber and dividing the second chamber into a positive pressure chamber near the top and a liquid storage chamber near the bottom, the liquid storage chamber being used to store a diluent, and the partition layer being provided with a through hole;

[0012] A sealing sheet, wherein the sealing sheet sealing cover is arranged at the bottom of the liquid storage cavity;

[0013] A sampling rod, the sampling rod is detachably inserted into the second chamber from the top of the shell, the sampling rod comprises a pinch handle, a sampling rod connected to the pinch handle, and a sealing assembly connected to the middle of the sampling rod, the sampling rod extends from the positive pressure chamber through the through hole into the liquid storage chamber, the sealing assembly can be in sealing contact with the hole wall of the through hole to separate the positive pressure chamber and the liquid storage chamber; the pinch handle is slidably and sealingly embedded in the top of the second chamber and is used to drive the sampling rod and the sealing assembly to move along the height direction of the second chamber, the sampling rod can pierce the sealing sheet driven by the pinch handle, and the sealing assembly can be in contact with or separated from the hole wall of the through hole driven by the sampling rod;

[0014] A base, wherein the base cover is arranged at the bottom of the shell, and a liquid passage cavity is arranged on the base, the liquid passage cavity is separated from the second cavity by the sealing sheet, and the liquid passage cavity is communicated with the first cavity;

[0015] A test strip is disposed in the first chamber and one end of the test strip extends into the liquid passage chamber.

[0016] The feces sample detection device of the utility model can at least achieve the following beneficial effects: when sampling and detection work is not performed, the sampling rod is inserted into the second chamber, and the sealing component closes the through hole of the partition layer, and the sealing component and the sealing sheet at the bottom of the shell together seal the diluent in the liquid storage chamber, which can prevent the diluent from contacting with the outside atmosphere and affecting the quality of the diluent, and can also avoid the diluent from leaking out and causing leakage. When sampling and detection work is to be performed, the sampling rod can be pulled out of the second chamber, and the end of the sampling rod of the sampling rod away from the pinch handle is brought into contact with feces to achieve sampling. Then the sampling rod is reinserted into the second chamber, and the end of the sampling rod away from the pinch handle is extended into the liquid storage chamber of the second chamber, and the feces on the sampling rod is contacted with the diluent in the liquid storage chamber to mix to form the liquid to be tested. During the mixing process, the shell can also be shaken to speed up the mixing speed and uniformity of the feces and the diluent. After the mixing is completed, the sampling rod can be slid downward, that is, the handle of the sampling rod slides toward the direction close to the isolation layer, the gas in the positive pressure chamber is squeezed and the air pressure increases, and the sampling rod fixed with the handle also moves downward and punctures the sealing sheet. At this time, the liquid storage chamber is connected with the liquid flow chamber; the sealing assembly on the sampling rod also escapes from the through hole, and the positive pressure chamber is connected with the liquid storage chamber. The higher air pressure above the liquid storage chamber will also help push the liquid to be tested to flow quickly into the liquid flow chamber below, so that the test strip can quickly absorb the liquid to be tested and speed up the detection efficiency. The entire sampling and testing process requires fewer steps. It is only necessary to pull out the sampling stick, reinsert it into the second chamber after completing the sampling, and puncture the sealing film. The professional requirements for testing personnel are low, which helps to reduce learning costs. During the testing process, when the sampling stick is pressed down, not only the sealing film is punctured to achieve the connection between the liquid storage chamber and the liquid flow chamber, but also a positive air pressure is generated above the liquid level to be tested in the liquid storage chamber, which can push the liquid to be tested into the liquid flow chamber as quickly as possible and contact with the test strip to speed up the testing speed. The entire second chamber is sealed, which can prevent feces from contacting the outside atmosphere and affecting the sample quality, and can also prevent feces from leaking out and causing pollution.

[0017] In one embodiment, the stool sample detection device has a state to be detected and a detection state; in the state to be detected, the sealing component is in sealing contact with the hole wall of the through hole to separate the positive pressure chamber and the liquid storage chamber, and the sealing component and the sealing sheet together seal the diluent in the liquid storage chamber; in the detection state, the sampling rod can be pulled out of the second chamber to sample stool and reinserted into the second chamber after sampling so that the stool and the diluent are mixed to form a liquid to be detected, and the end of the sampling rod extending into the liquid storage chamber can pierce the sealing sheet under the drive of the pinch handle, so that the liquid storage chamber and the liquid passage chamber are connected so that the liquid to be detected flows into the liquid passage chamber and is absorbed by the test strip. In the state to be detected, the sampling rod is inserted into the second chamber, the sealing component seals the through hole of the partition layer, and the sealing component and the sealing sheet at the bottom of the shell together seal the diluent in the liquid storage chamber, which can prevent the diluent from contacting with the outside atmosphere and affecting the quality of the diluent, and can also avoid leakage of the diluent. In the detection state, when sampling and detection work is to be carried out, the sampling rod can be pulled out from the second chamber, and the end of the sampling rod of the sampling rod away from the pinch handle is brought into contact with feces to achieve sampling. Then the sampling rod is reinserted into the second chamber, and the end of the sampling rod away from the pinch handle is extended into the liquid storage cavity of the second chamber. The feces on the sampling rod is contacted and mixed with the diluent in the liquid storage cavity to form the liquid to be tested. During the mixing process, the shell can also be shaken to speed up the mixing speed and uniformity of the feces and the diluent. After the mixing is completed, the sampling rod can be slid downward, and the sampling rod fixed with the pinch handle also moves downward and punctures the sealing sheet. At this time, the liquid storage cavity is connected with the liquid passage cavity.

[0018] In one of the embodiments, in the detection state, the handle moves in the positive pressure chamber in a direction close to the isolation layer to increase the air pressure in the positive pressure chamber, and when the sampling rod pierces the sealing sheet driven by the handle, the sealing component is separated from the hole wall of the through hole driven by the sampling rod. In the state to be detected, the sampling rod is slid downward, that is, the handle of the sampling rod slides in a direction close to the isolation layer, the gas in the positive pressure chamber is squeezed and the air pressure increases, the sampling rod fixed with the handle also moves downward together, and the sealing component on the sampling rod also escapes from the through hole, the positive pressure chamber is connected with the liquid storage chamber, and the higher air pressure above the liquid storage chamber will also help push the liquid to be detected to flow rapidly into the liquid chamber below, so that the test strip quickly absorbs the liquid to be detected and speeds up the detection efficiency.

[0019] In one embodiment, the inner contour of the cross-section of the second chamber is circular, an unlocking groove is provided on the top of the second chamber, a part of the handle is rotatably inserted into the top of the second chamber, and a limiting column is convexly provided on the outer circumference of the handle, and the limiting column can be rotated relative to the second chamber to a locked position and an unlocked position; in the locked position, the limiting column can abut against the top edge of the second chamber to limit the depth of the sampling rod entering the second chamber, and make the end of the sampling rod extending into the liquid storage chamber spaced from the sealing sheet; in the unlocking position, the limiting column can enter the unlocking groove, so that the handle can slide in the direction close to the partition layer, and the end of the sampling rod extending into the liquid storage chamber can move in the direction close to the sealing sheet and puncture the sealing sheet under the drive of the handle. In the locking position, if sampling has not been performed or if the collected stool sample is still to be mixed with the diluent in the liquid storage chamber for a while, the limiting column is located outside the unlocking slot, that is, the limiting column is not aligned and cannot enter the unlocking slot, and the limiting column abuts against the top edge of the second chamber, which can prevent the pinch handle from moving in the direction close to the sealing sheet, and the end of the sampling rod close to the sealing sheet always maintains a certain distance from the sealing sheet, so that the pinch handle of the sampling rod can be accidentally touched and cause the sealing sheet to be punctured. In the unlocking position, if sampling is completed and the stool sample and the diluent are mixed, the limiting column on the pinch handle can be turned to the top of the unlocking slot, and the unlocking slot provides space for the limiting column to move downward in the height direction of the shell, and the limiting column enters the unlocking slot, and the pinch handle can also be pressed down and slid, so that the end of the sampling rod extending into the liquid storage chamber can also move downward and puncture the sealing sheet, thereby realizing the connection between the liquid storage chamber and the liquid passage chamber, so that the mixed liquid to be tested flows into the liquid passage chamber and is finally absorbed by the test strip.

[0020] In one embodiment, the liquid passage chamber includes a drainage groove and a liquid receiving groove connected to the drainage groove, the liquid receiving groove is located below the drainage groove and connected to the first chamber, the drainage groove is located below the liquid storage chamber and is separated from the liquid storage chamber by the sealing sheet, and the drainage groove is trumpet-shaped and faces the liquid storage chamber.

[0021] In one embodiment, the end of the sampling rod away from the pinch handle is tapered. The tapered end of the sampling rod is sharper and can pierce the sealing sheet more effectively.

[0022] In one embodiment, the outer peripheral surface of the sampling rod away from the grip is provided with threads, and the gaps between the threads can better wrap part of the feces sample, so as to achieve effective collection of the sample.

[0023] In one embodiment, the sealing assembly includes a sealing block adapted to the through hole and a first sealing ring sleeved on the outer circumference of the sealing block. When the sealing assembly is located in the through hole, the first sealing ring seals between the outer circumference of the sealing block and the wall of the through hole.

[0024] In one embodiment, the outer peripheral surface of the sealing block is provided with a first limiting groove, the first limiting groove extends in a ring shape along the circumference of the sealing block, the first sealing ring is fixedly embedded in the first limiting groove, and the first sealing ring at least partially protrudes from the outer peripheral surface of the sealing block. The first limiting groove can limit the movement of the first sealing ring, prevent the first sealing ring from falling off the sealing block, and ensure that the sealing assembly as a whole effectively seals the through hole.

[0025] In one embodiment, the inner contour of the cross section of the through hole is circular.

[0026] In one embodiment, a second sealing ring is sleeved on the outer circumference of the handle, and when the handle is inserted into the positive pressure chamber, the second sealing ring abuts between the outer circumference of the handle and the inner circumference of the positive pressure chamber.

[0027] In one embodiment, a second limiting groove is formed on the outer circumference of the handle, and the second sealing ring is fixedly embedded in the second limiting groove, and the second sealing ring at least partially protrudes from the outer circumference of the handle. The second limiting groove can limit the movement of the second sealing ring, prevent the second sealing ring from falling off the handle, and ensure that when the sampling rod is inserted into the second chamber, the handle and the second sealing ring as a whole effectively seal the positive pressure chamber of the second chamber.

[0028] In one embodiment, a window is provided on the side wall of the first chamber, and the window is used for a user to observe the test result of the test strip.

[0029] In one embodiment, the stool sample detection device further includes a test strip holder inserted into the first chamber, the test strip holder is provided with a slot, and the test strip is fixed in the slot.

[0030] In one embodiment, the test strip includes absorbent paper with water absorption function, a nitrocellulose membrane coated with a detection line and a quality control line, a protein coupling pad coated with a labeled protein, and a sample pad for absorbing the liquid to be tested, which are connected in sequence along the length extension direction of the test strip. One end of the test strip with a sample pad is close to the liquid passage chamber.

[0031] In one embodiment, the base is detachably mounted on the outer circumferential surface of the shell, a third sealing ring is fixed on the outer circumferential surface of the bottom of the shell, the third sealing ring is sealingly abutted between the shell and the base, either the shell or the base is provided with a snap-fitting protrusion, and the other of the shell and the base is provided with a snap-fitting recess, and the snap-fitting protrusion and the snap-fitting recess of the base cooperate to be fixed to the shell. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the conventional technology, the drawings required for use in the embodiments or the conventional technology descriptions are briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0033] Figure 1 An exploded schematic diagram of a stool sample detection device provided by one embodiment of the utility model.

[0034] Figure 2 A perspective schematic diagram of a stool sample detection device provided by an embodiment of the utility model.

[0035] Figure 3 A schematic side view of a stool sample detection device provided by one embodiment of the utility model.

[0036] Figure 4 A schematic diagram of a housing of a stool sample detection device provided by one embodiment of the utility model.

[0037] Figure 5 A schematic structural diagram of a sampling rod provided in one embodiment of the utility model.

[0038] Figure 6 A structural schematic diagram of a base provided in one embodiment of the utility model.

[0039] Figure 7 A schematic structural diagram of a test strip provided in one embodiment of the utility model.

[0040] Reference numerals:

[0041] 10. Fecal sample detection device; 100. Housing; 110. First chamber; 111. Window; 120. Second chamber; 121. Positive pressure chamber; 122. Liquid storage chamber; 130. Third sealing ring; 140. Unlocking groove; 150. Snap-on recess; 200. Partition layer; 210. Through hole; 300. Sealing sheet; 400. Sampling rod; 410. Pinch handle; 411. Limiting column; 412. Second sealing ring; 420. Sampling Rod; 430, sealing assembly; 431, first sealing ring; 432, sealing block; 500, base; 510, liquid chamber; 511, drainage groove; 512, liquid receiving groove; 520, snap-on protrusion; 600, test strip; 610, absorbent paper; 620, nitrocellulose membrane; 621, detection line; 622, quality control line; 630, protein coupling pad; 640, sample pad; 700, test strip holder; 710, card slot. DETAILED DESCRIPTION

[0042] In order to make the above-mentioned purposes, features and advantages of the utility model more obvious and easy to understand, the specific implementation methods of the utility model are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the utility model. However, the utility model can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the utility model, so the utility model is not limited by the specific embodiments disclosed below.

[0043] See also Figures 1 to 5 In some embodiments, the present invention provides a stool sample detection device 10, which includes a housing 100, a partition layer 200, a sealing sheet 300, a sampling rod 400, a base 500, a test strip 600 and a test strip holder 700. Figure 3 and Figure 4 As shown, the shell 100 is formed with a first chamber 110 and a second chamber 120 which are independent of each other, and the first chamber 110 and the second chamber 120 both penetrate the top and the bottom of the shell 100 along the height direction of the shell 100; Figure 4 As shown, the barrier layer 200 is disposed in the second chamber 120 and divides the second chamber 120 into a positive pressure chamber 121 near the top and a liquid storage chamber 122 near the bottom. The liquid storage chamber 122 is used to store diluent. A through hole 210 is opened on the barrier layer 200. Figure 3 As shown, the sealing sheet 300 is sealed and covered at the bottom of the liquid storage chamber 122; Figure 3 and Figure 5As shown, the sampling rod 400 is detachably inserted into the second chamber 120 from the top of the housing 100, and the sampling rod 400 includes a grip 410, a sampling rod 420 connected to the grip 410, and a sealing assembly 430 connected to the middle of the sampling rod 420. The sampling rod 420 extends from the positive pressure chamber 121 through the through hole 210 into the liquid storage chamber 122, and the sealing assembly 430 can be sealed against the hole wall of the through hole 210 to separate the positive pressure chamber 121 and the liquid storage chamber 122; the grip 410 is slidably and sealingly embedded in the top of the second chamber 120 and is used to drive the sampling rod 420 and the sealing assembly 430. 0 moves along the height direction of the second chamber 120, the sampling rod 420 can pierce the sealing sheet 300 under the drive of the pinch handle 410, and the sealing assembly 430 can abut or separate from the hole wall of the through hole 210 under the drive of the sampling rod 420; the base 500 is covered on the bottom of the housing 100, and a liquid passage cavity 510 is provided on the base 500, and the liquid passage cavity 510 is separated from the second chamber 120 by the sealing sheet 300, and the liquid passage cavity 510 is connected with the first chamber 110; the test strip 600 is arranged in the first chamber 110 and one end of the test strip 600 extends into the liquid passage cavity 510. Wherein, the sealing sheet 300 may include but is not limited to aluminum foil, etc.

[0044] The above-mentioned stool sample detection device 10 can at least achieve the following beneficial effects: when sampling and detection work is not performed, the sampling rod 400 is inserted into the second chamber 120, and the sealing component 430 closes the through hole 210 of the partition layer 200, and it and the sealing sheet 300 at the bottom of the shell 100 seal the diluent in the liquid storage chamber 122, which can prevent the diluent from contacting with the outside atmosphere and affecting the quality of the diluent, and can also avoid the diluent from leaking and causing leakage. When sampling and detection work is to be performed, the sampling rod 400 can be pulled out of the second chamber 120, and the end of the sampling rod 420 of the sampling rod 400 away from the pinch handle 410 is brought into contact with feces to achieve sampling. The sampling rod 400 is then inserted back into the second chamber 120, and the end of the sampling rod 420 away from the handle 410 extends into the liquid storage chamber 122 of the second chamber 120. The feces on the sampling rod 420 contacts and mixes with the diluent in the liquid storage chamber 122 to form the liquid to be tested. During the mixing process, the shell 100 can also be shaken to speed up the mixing speed and uniformity of the feces and the diluent. After the mixing is completed, the sampling rod 400 can be slid downward, that is, the handle 410 of the sampling rod 400 slides toward the direction close to the isolation layer 200, and the gas in the positive pressure chamber 121 is squeezed and the air pressure increases, and the sampling rod 420 fixed with the handle 410 also moves downward and punctures the sealing sheet 300. At this time, the liquid storage chamber 122 is connected with the liquid flow chamber 510; the sealing assembly 430 on the sampling rod 420 also escapes from the through hole 210, and the positive pressure chamber 121 is connected with the liquid storage chamber 122. The higher air pressure above the liquid storage chamber 122 will also help push the liquid to be tested to flow quickly into the liquid flow chamber 510 below, so that the test strip 600 can quickly absorb the liquid to be tested and speed up the detection efficiency. The entire sampling and testing process requires fewer steps. It is only necessary to pull out the sampling stick 400, complete the sampling, reinsert it into the second chamber 120, and puncture the sealing sheet 300. The professional requirements for the test personnel are relatively low, which helps to reduce the learning cost. During the testing process, when the sampling stick 400 is pressed down, not only the sealing sheet 300 is punctured to achieve the connection between the liquid storage chamber 122 and the liquid passage chamber 510, but also a positive air pressure is generated above the liquid surface to be tested in the liquid storage chamber 122, which can push the liquid to be tested into the liquid passage chamber 510 as soon as possible and contact with the test strip 600 to speed up the testing speed. The entire second chamber 120 is sealed, which can prevent feces from contacting the outside atmosphere and affecting the sample quality, and can also prevent feces from leaking out and causing pollution.

[0045] Specifically, in some embodiments, the stool sample detection device 10 has a state to be detected and a detection state; in the state to be detected, the sealing component 430 is sealed against the hole wall of the through hole 210 to separate the positive pressure chamber 121 and the liquid storage chamber 122, and the sealing component 430 and the sealing sheet 300 jointly seal the diluent in the liquid storage chamber 122; in the detection state, the sampling rod 400 can be pulled out from the second chamber 120 for stool sampling and reinserted into the second chamber 120 after sampling so that the stool and the diluent are mixed to form a liquid to be detected, and the end of the sampling rod 420 extending into the liquid storage chamber 122 can pierce the sealing sheet 300 under the drive of the pinch handle 410, so that the liquid storage chamber 122 is connected with the liquid passage chamber 510 so that the liquid to be detected flows into the liquid passage chamber 510 and is absorbed by the test strip 600. In the state to be detected, the sampling rod 400 is inserted into the second chamber 120, and the sealing assembly 430 closes the through hole 210 of the partition layer 200, and the sealing assembly 430 and the sealing sheet 300 at the bottom of the housing 100 seal the diluent in the liquid storage chamber 122, which can prevent the diluent from contacting with the outside atmosphere and affecting the quality of the diluent, and can also avoid leakage of the diluent. In the detection state, when sampling and detection work is to be carried out, the sampling rod 400 can be pulled out of the second chamber 120, and the end of the sampling rod 420 of the sampling rod 400 away from the pinch handle 410 is brought into contact with feces to achieve sampling. Then, the sampling rod 400 is inserted back into the second chamber 120, and the end of the sampling rod 420 away from the pinch handle 410 is extended into the liquid storage chamber 122 of the second chamber 120. The feces on the sampling rod 420 is contacted with the diluent in the liquid storage chamber 122 and mixed to form the liquid to be tested. During the mixing process, the housing 100 can also be shaken to speed up the mixing speed and uniformity of the feces and the diluent. After the mixing is completed, the sampling rod 400 can be slid downward, and the sampling rod 420 fixed with the pinch handle 410 also moves downward and punctures the sealing sheet 300. At this time, the liquid storage chamber 122 is connected to the liquid passage chamber 510.

[0046] More specifically, in some of the embodiments, in the detection state, the handle 410 moves in the positive pressure chamber 121 in a direction close to the isolation layer 200 to increase the air pressure in the positive pressure chamber 121, and when the sampling rod 420 pierces the sealing sheet 300 driven by the handle 410, the sealing assembly 430 is separated from the hole wall of the through hole 210 driven by the sampling rod 420. When in the state to be detected, the sampling rod 400 is slid downward, that is, the handle 410 of the sampling rod 400 slides toward the direction close to the isolation layer 200, the gas in the positive pressure chamber 121 is squeezed and the air pressure increases, and the sampling rod 420 fixed with the handle 410 also moves downward and the sealing assembly 430 on the sampling rod 420 also escapes from the through hole 210, the positive pressure chamber 121 is connected with the liquid storage chamber 122, and the higher air pressure above the liquid storage chamber 122 will also help push the liquid to be detected to flow quickly into the liquid passage chamber 510 below, so that the test strip 600 quickly absorbs the liquid to be detected, thereby accelerating the detection efficiency.

[0047] See also Figure 1 , Figure 2 and Figure 5In some embodiments, the inner contour of the cross section of the second chamber 120 is circular, an unlocking groove 140 is provided at the top of the second chamber 120, a portion of the handle 410 is rotatably inserted at the top of the second chamber 120, and a limiting column 411 is convexly provided on the outer peripheral surface of the handle 410, and the limiting column 411 can be rotated relative to the second chamber 120 to a locked position and an unlocked position; in the locked position, the limiting column 411 can abut against the top edge of the second chamber 120 to limit The sampling rod 400 enters the depth of the second chamber 120, and the end of the sampling rod 420 extending into the liquid storage chamber 122 is spaced apart from the sealing sheet 300; when in the unlocking position, the limiting column 411 can enter the unlocking groove 140, so that the handle 410 can slide toward the direction close to the partition layer 200, and the end of the sampling rod 420 extending into the liquid storage chamber 122 can move toward the direction close to the sealing sheet 300 and puncture the sealing sheet 300 under the drive of the handle 410. When in the locked position, if sampling has not been performed or the collected feces sample is still to be mixed with the diluent in the liquid storage chamber 122 for a while, the limiting column 411 is located outside the unlocking slot 140, that is, the limiting column 411 is not aligned and cannot enter the unlocking slot 140, and the limiting column 411 abuts against the top edge of the second chamber 120, which can prevent the handle 410 from moving in the direction close to the sealing sheet 300. The end of the sampling rod 420 close to the sealing sheet 300 always maintains a certain distance from the sealing sheet 300, so that the handle 410 of the sampling rod 400 can be accidentally touched and cause the sealing sheet 300 to be punctured. When in the unlocking position, after sampling is completed and the stool sample and the diluent are mixed, the limiting post 411 on the pinch handle 410 can be rotated to the top of the unlocking slot 140. The unlocking slot 140 provides space for the limiting post 411 to move downward in the height direction of the shell 100. The limiting post 411 enters the unlocking slot 140, and the pinch handle 410 can also be pressed down and slid. Then, the end of the sampling rod 420 extending into the liquid storage chamber 122 can also move downward and pierce the sealing sheet 300, thereby realizing the connection between the liquid storage chamber 122 and the liquid passage chamber 510, so that the mixed liquid to be tested flows into the liquid passage chamber 510 and is finally absorbed by the test strip 600.

[0048] See also Figure 3 In some embodiments, the liquid passage chamber 510 includes a drainage groove 511 and a liquid receiving groove 512 connected to the drainage groove 511, the liquid receiving groove 512 is located below the drainage groove 511 and is connected to the first chamber 110, the drainage groove 511 is located below the liquid storage chamber 122 and is separated from the liquid storage chamber 122 by the sealing sheet 300, and the drainage groove 511 is trumpet-shaped and faces the liquid storage chamber 122.

[0049] See also Figure 3 and Figure 5 In some embodiments, the end of the sampling rod 420 away from the pinch handle 410 is tapered. The tapered end of the sampling rod 420 is sharper and can pierce the sealing sheet 300 more effectively.

[0050] Furthermore, if Figure 5 As shown, in some embodiments, the outer peripheral surface of the sampling rod 420 at one end away from the pinch handle 410 is provided with threads. The gap between the threads can better wrap a part of the feces sample, so as to achieve effective collection of the sample.

[0051] Furthermore, if Figure 5 As shown, in some embodiments, the sealing assembly 430 includes a sealing block 432 adapted to the through hole 210 and a first sealing ring 431 sleeved on the outer circumference of the sealing block 432. When the sealing assembly 430 is located in the through hole 210, the first sealing ring 431 seals and abuts between the outer circumference of the sealing block 432 and the wall of the through hole 210.

[0052] Furthermore, in some embodiments, a first limiting groove is formed on the outer circumferential surface of the sealing block 432, and the first limiting groove extends in a ring shape along the circumferential direction of the sealing block 432. The first sealing ring 431 is fixedly embedded in the first limiting groove, and the first sealing ring 431 at least partially protrudes from the outer circumferential surface of the sealing block 432. The first limiting groove can limit the movement of the first sealing ring 431, prevent the first sealing ring 431 from falling off the sealing block 432, and ensure that the sealing assembly 430 as a whole effectively seals the through hole 210.

[0053] Furthermore, in some embodiments, the inner contour of the cross section of the through hole 210 is circular.

[0054] See also Figure 5 In some embodiments, a second sealing ring 412 is sleeved on the outer circumference of the handle 410 , and when the handle 410 is inserted into the positive pressure chamber 121 , the second sealing ring 412 abuts between the outer circumference of the handle 410 and the inner circumference of the positive pressure chamber 121 .

[0055] Furthermore, in some embodiments, a second limiting groove is provided on the outer circumference of the handle 410, and the second sealing ring 412 is fixedly embedded in the second limiting groove, and the second sealing ring 412 at least partially protrudes from the outer circumference of the handle 410. The second limiting groove can limit the movement of the second sealing ring 412, prevent the second sealing ring 412 from falling off the handle 410, and ensure that when the sampling rod 400 is inserted into the first chamber 110, the handle 410 and the second sealing ring 412 as a whole effectively seal the positive pressure chamber 121 of the second chamber 120.

[0056] See also Figure 1 In some embodiments, a window 111 is provided on the side wall of the first chamber 110 , and the window 111 is used for a user to observe the test result of the test strip 600 .

[0057] See also Figure 1 In some embodiments, the stool sample testing device 10 further includes a test strip holder 700 inserted into the first chamber 110 , and a slot 710 is formed on the test strip holder 700 , and the test strip 600 is fixed in the slot 710 .

[0058] See also Figure 7 In some embodiments, the test strip 600 includes absorbent paper 610 with water absorption function connected in sequence along its own length extension direction, a nitrocellulose membrane 620 coated with a detection line 621 and a quality control line 622, a protein coupling pad 630 coated with a marker protein, and a sample pad 640 for absorbing the liquid to be tested, and the test strip 600 is provided with one end of the sample pad 640 close to the liquid passage cavity. The utility model does not limit the specific type of the test strip 600, which can be a Helicobacter pylori (HP) detection reagent strip, a fecal occult blood detection reagent strip, or a transferrin detection reagent strip. The present application also does not limit the specific number of test strips 600 placed in the first chamber 110. In theory, multiple test strips 600 of different types can be placed and multiple different indicators can be measured at the same time.

[0059] See also Figure 1 and Figure 6 In some embodiments, the base 500 is detachably mounted on the outer circumferential surface of the shell 100, and a third sealing ring 130 is fixed on the outer circumferential surface of the bottom of the shell 100. The third sealing ring 130 is sealingly abutted between the shell 100 and the base 500. Either the shell 100 or the base 500 is provided with a snap-fitting protrusion 520, and the other of the shell 100 and the base 500 is provided with a snap-fitting recess 150. The snap-fitting protrusion 520 of the base 500 cooperates with the snap-fitting recess 150 to be fixed to the shell 100.

[0060] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0061] The above-mentioned embodiments only express several implementation methods of the utility model, and the description is relatively specific and detailed, but it cannot be understood as limiting the scope of the patent application. It should be pointed out that for ordinary technicians in this field, several modifications and improvements can be made without departing from the concept of the utility model, which all belong to the protection scope of the utility model. Therefore, the protection scope of the utility model patent shall be based on the attached claims.

[0062] In the description of the present invention, it should be understood that if the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. appear, the orientation or position relationship indicated by these terms is based on the orientation or position relationship shown in the accompanying drawings, which is only for the convenience of describing the present invention and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0063] In addition, if the terms "first" or "second" appear, these terms are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" or "second" may explicitly or implicitly include at least one of the features. In the description of the present utility model, if the term "plurality" appears, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0064] In the present invention, unless otherwise clearly defined and limited, if the terms "installed", "connected", "connected", "fixed" and the like appear, these terms should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integrated connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to the specific circumstances.

[0065] In the present utility model, unless otherwise clearly specified and limited, if there is a description that a first feature is "above" or "below" a second feature, etc., or similar descriptions appear, it may mean that the first and second features are in direct contact, or that the first and second features are in indirect contact through an intermediate medium. Moreover, the first feature being "above", "above" and "above" the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. The first feature being "below", "below" and "below" the second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0066] It should be noted that if an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be a central element. If an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be a central element at the same time. If any, the terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used in this utility model are only for illustrative purposes and do not represent the only implementation method.

[0067] In the description of this specification, the description of reference terms such as "one embodiment", "other implementation methods" and the like means that the specific features, structures, materials or features described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic descriptions of the above terms do not necessarily refer to the same embodiment or example. Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by technicians in the technical field of the present invention. The terms used herein in the specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention.

Claims

1. A stool sample detection device, characterized in that: include: A shell, wherein a first chamber and a second chamber that are independent of each other are formed in the shell, and the first chamber and the second chamber both penetrate the top and the bottom of the shell along the height direction of the shell; a partition layer, the partition layer being arranged in the second chamber and dividing the second chamber into a positive pressure chamber near the top and a liquid storage chamber near the bottom, the liquid storage chamber being used to store a diluent, and the partition layer being provided with a through hole; A sealing sheet, wherein the sealing sheet sealing cover is arranged at the bottom of the liquid storage cavity; A sampling rod, the sampling rod is detachably inserted into the second chamber from the top of the shell, the sampling rod comprises a pinch handle, a sampling rod connected to the pinch handle, and a sealing assembly connected to the middle of the sampling rod, the sampling rod extends from the positive pressure chamber through the through hole into the liquid storage chamber, the sealing assembly can be in sealing contact with the hole wall of the through hole to separate the positive pressure chamber and the liquid storage chamber; the pinch handle is slidably and sealingly embedded in the top of the second chamber and is used to drive the sampling rod and the sealing assembly to move along the height direction of the second chamber, the sampling rod can move downward in the height direction driven by the pinch handle to puncture the sealing sheet, and the sealing assembly can be in contact with or separated from the hole wall of the through hole driven by the sampling rod; A base, wherein the base cover is arranged at the bottom of the shell, and a liquid passage cavity is arranged on the base, the liquid passage cavity is separated from the second cavity by the sealing sheet, and the liquid passage cavity is communicated with the first cavity; A test strip is disposed in the first chamber and one end of the test strip extends into the liquid passage chamber.

2. The stool sample detection device according to claim 1, characterized in that: The stool sample detection device has a state to be detected and a detection state; in the state to be detected, the sealing component is in sealing contact with the hole wall of the through hole to separate the positive pressure chamber and the liquid storage chamber, and the sealing component and the sealing sheet jointly seal the diluent in the liquid storage chamber; in the detection state, the sampling rod can be pulled out of the second chamber for stool sampling and reinserted into the second chamber after sampling so that the stool and the diluent are mixed to form a liquid to be detected, and the end of the sampling rod extending into the liquid storage chamber can pierce the sealing sheet under the drive of the pinch handle, so that the liquid storage chamber is connected with the liquid passage chamber so that the liquid to be detected flows into the liquid passage chamber and is absorbed by the test strip.

3. The stool sample detection device according to claim 2, characterized in that: In the detection state, the handle moves in the positive pressure chamber in a direction close to the isolation layer to increase the air pressure in the positive pressure chamber, and when the sampling rod pierces the sealing sheet driven by the handle, the sealing assembly is separated from the hole wall of the through hole driven by the sampling rod.

4. The stool sample detection device according to any one of claims 1 to 3, characterized in that: The inner contour of the cross-section of the second chamber is circular, an unlocking groove is provided on the top of the second chamber, a part of the handle is rotatably inserted in the top of the second chamber, and a limiting column is convexly provided on the outer circumferential surface of the handle, and the limiting column can be rotated relative to the second chamber to a locking position and an unlocking position; in the locking position, the limiting column can abut against the top edge of the second chamber to limit the depth of the sampling rod entering the second chamber, and make the end of the sampling rod extending into the liquid storage chamber spaced from the sealing sheet; in the unlocking position, the limiting column can enter the unlocking groove, so that the handle can slide in the direction close to the partition layer, and the end of the sampling rod extending into the liquid storage chamber can move in the direction close to the sealing sheet and puncture the sealing sheet under the drive of the handle.

5. The stool sample detection device according to any one of claims 1 to 3, characterized in that: The liquid passage cavity comprises a drainage groove and a liquid receiving groove connected with the drainage groove, wherein the liquid receiving groove is located below the drainage groove and connected with the first chamber, the drainage groove is located below the liquid storage cavity and is separated from the liquid storage cavity by the sealing sheet, and the drainage groove is trumpet-shaped and faces the liquid storage cavity; And / or, the end of the sampling rod away from the handle is tapered; And / or, the outer peripheral surface of one end of the sampling rod away from the pinching handle is provided with a thread.

6. The stool sample detection device according to any one of claims 1 to 3, characterized in that: The sealing assembly includes a sealing block adapted to the through hole and a first sealing ring sleeved on the outer circumference of the sealing block. When the sealing assembly is located in the through hole, the first sealing ring seals between the outer circumference of the sealing block and the wall of the through hole.

7. The stool sample detection device according to claim 6, characterized in that: The outer peripheral surface of the sealing block is provided with a first limiting groove, the first limiting groove extends in a ring shape along the circumference of the sealing block, the first sealing ring is fixedly embedded in the first limiting groove, and the first sealing ring at least partially protrudes from the outer peripheral surface of the sealing block; And / or, the inner contour of the cross section of the through hole is circular.

8. The stool sample detection device according to any one of claims 1 to 3, characterized in that: A second sealing ring is sleeved on the outer circumferential surface of the handle. When the handle is inserted into the positive pressure chamber, the second sealing ring abuts between the outer circumferential surface of the handle and the inner circumferential surface of the positive pressure chamber.

9. The stool sample detection device according to claim 8, characterized in that: A second limiting groove is formed on the outer peripheral surface of the handle, the second sealing ring is fixedly embedded in the second limiting groove, and the second sealing ring at least partially protrudes from the outer peripheral surface of the handle.

10. The stool sample detection device according to any one of claims 2 to 3, characterized in that: A window is provided on the side wall of the first chamber, and the window is used for a user to observe the test result of the test strip; And / or, the stool sample detection device further comprises a test strip holder inserted into the first chamber, the test strip holder is provided with a slot, and the test strip is fixed in the slot; And / or, the test strip comprises absorbent paper with water absorption function, a nitrocellulose membrane coated with a detection line and a quality control line, a protein coupling pad coated with a marker protein, and a sample pad for absorbing the liquid to be tested, which are sequentially connected along the length extension direction of the test strip, and one end of the test strip provided with the sample pad is close to the liquid passage cavity; And / or, the base is detachably mounted on the outer circumferential surface of the shell, a third sealing ring is fixed on the outer circumferential surface of the bottom of the shell, the third sealing ring is sealingly abutted between the shell and the base, either the shell or the base is provided with a snap-fitting protrusion, the other of the shell and the base is provided with a snap-fitting recess, the snap-fitting protrusion of the base cooperates with the snap-fitting recess to be fixed to the shell.

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