Dialysis filter for sericin production

Abstract

The utility model discloses a dialysis filter for sericin production, which comprises a connecting base, a peristaltic hose pump and a dialysis filter cartridge, one side of the top of the connecting base is connected with a dialysate storage barrel, the peristaltic hose pump is connected to the top of the dialysate storage barrel, and the dialysis filter cartridge is connected with the connecting base. A liquid inlet connecting sleeve and a liquid outlet connecting sleeve are arranged on one side of the peristaltic hose pump, a liquid inlet pipe is connected into the liquid inlet connecting sleeve, a glue solution barrel is connected to the end, away from the peristaltic hose pump, of the liquid inlet pipe, a glue solution supplementing pipe is connected to the top of the glue solution barrel, a dialysate supplementing pipe is connected to one side of the dialysate storage barrel, and a liquid outlet pipe is connected to the other side of the dialysate storage barrel. The side, away from the dialysate supplementing pipe, of the dialysate storage barrel is connected with a fixed lantern ring, the dialysis filter cartridge is connected into the fixed lantern ring, and the side, away from the dialysate storage barrel, of the dialysis filter cartridge is provided with a waste liquid collecting barrel. Therefore, the purity of the extracted sericin protein is ensured.

Description

Technical Field

[0001] The utility model relates to the technical field of sericin production, in particular to a dialysis filter for sericin production. Background Art

[0002] Silk Fiber Protein is derived from natural silkworm cocoons. It has good biocompatibility and a series of unique biological properties. It is a natural biomaterial with excellent performance. The unique amino acid composition and structural properties of silk Fiber Protein give it good water solubility, cell adhesion and proliferation promotion, in situ fluorescence, antioxidant activity and tyrosinase inhibition activity. When extracting silk Fiber Protein, it needs to go through silk fibroin-hydrolysis-filtration and purification-filtrate pH test adjustment-concentration-sterilization-finished product.

[0003] The patent retrieved with application number CN202210699206.2 proposes a sericin protein extraction process, which improves the extraction rate of sericin protein and can realize the one-time large-scale sericin extraction of cocoon fragments, greatly improving work efficiency, and thus realizing the extraction of large quantities of sericin protein to meet social needs.

[0004] Similar to the above-mentioned sericin extraction process, although it improves the extraction rate of sericin and can realize the one-time large-scale sericin extraction of cocoon fragments, greatly improving the work efficiency and thus realizing the large-scale sericin extraction, it is only filtered through a filter and cannot effectively filter and extract the sericin completely, thereby failing to guarantee the purity of the extracted sericin.

[0005] Therefore, in view of this, the existing structure and defects are studied and improved, and a dialysis filter for sericin production is proposed, in order to achieve a more practical purpose. Utility Model Content

[0006] The purpose of the utility model is to provide a dialysis filter for sericin production to solve the problem that a sericin extraction process in the above background is only filtered through a filter screen and cannot effectively filter and extract the sericin completely, thereby failing to ensure the purity of the extracted sericin.

[0007] To achieve the above-mentioned purpose, the utility model provides the following technical solutions: a dialysis filter machine for producing sericin protein, comprising a connecting base, a peristaltic hose pump and a dialysis filter cartridge, wherein one side of the top of the connecting base is connected to a dialysis fluid storage barrel, and the peristaltic hose pump is connected to the top of the dialysis fluid storage barrel, one side of the peristaltic hose pump is provided with an inlet connecting sleeve and a liquid outlet connecting sleeve, the inlet connecting sleeve is connected with an inlet pipe, and the end of the inlet pipe away from the peristaltic hose pump is connected to a glue barrel, the top of the glue barrel is connected with a supplementary glue pipe, one side of the dialysis fluid storage barrel is connected with a dialysis fluid infusion pipe, and the side of the dialysis fluid storage barrel away from the dialysis fluid infusion pipe is connected with a fixing ring, the dialysis filter cartridge is connected in the fixing ring, and a waste liquid collection barrel is provided on the side of the dialysis filter cartridge away from the dialysis fluid storage barrel.

[0008] Preferably, a liquid outlet pipe is connected between the liquid outlet connecting sleeve and the dialysis filter cartridge, a gel protein collecting bucket is provided below the dialysis filter cartridge, and a filtration connecting tube is connected between the gel protein collecting bucket and the dialysis filter cartridge.

[0009] Preferably, a gel protein channel is provided in the dialysis filter cartridge, and a dialysis membrane is connected to the outside of the gel protein channel, and a waste liquid connecting pipe is connected between the dialysis filter cartridge and the waste liquid collection bucket.

[0010] Preferably, a dialysate delivery pipe is connected below the waste liquid connecting pipe, a liquid delivery pump is connected to one end of the dialysate delivery pipe away from the dialysate filter cartridge, and a liquid extraction pipe is connected between the liquid delivery pump and the dialysate storage barrel.

[0011] Preferably, a pump body motor is connected to one side of the peristaltic hose pump, a liquid delivery pump core is arranged at the center of the peristaltic hose pump, and the liquid delivery pump core is connected to the pump body motor, and extrusion liquid delivery wheels are connected to both sides of the liquid delivery pump core.

[0012] Preferably, an infusion hose is provided in the peristaltic hose pump, and two ends of the infusion hose are respectively connected to a liquid inlet connecting sleeve and a liquid outlet connecting sleeve, and the infusion hose is respectively tangent to two sets of extrusion liquid delivery wheels.

[0013] Compared with the prior art, the beneficial effect of the present invention is that the impurities in the sericin protein are effectively removed by dialysis filtration, thereby ensuring the purity of the extracted sericin protein. The specific contents are as follows:

[0014] The sericin liquid that needs to be dialyzed and filtered is added into the liquid barrel through the liquid replenishing tube. The dialysate in the dialysate storage barrel can be replenished with the dialysate through the dialysate replenishing tube. The sericin liquid in the liquid barrel is pumped into the pump body through the liquid inlet tube by the peristaltic hose pump, and the sericin liquid is sent into the dialysis filter cartridge through the liquid outlet connecting sleeve and the liquid outlet tube. The pump body motor drives the liquid delivery pump core to rotate, and the liquid delivery wheels on both sides of the liquid delivery pump core squeeze the infusion hose, and the sericin liquid is pumped into the dialysis filter cartridge through the pump body motor. The liquid enters the gelatin protein channel, and at the same time, the dialysate in the dialysate storage tank is sent into the dialysis filter cartridge through the dialysate delivery tube by the liquid delivery pump through the liquid extraction tube, and the sericin liquid enters the gelatin protein channel and is dialyzed and filtered through the outer dialysis membrane, and the impurities in the sericin protein liquid enter the waste liquid connecting tube, and the waste liquid is discharged into the waste liquid collecting barrel by the waste liquid connecting tube, and the sericin filtered by the dialysis filter cartridge is sent into the gelatin protein collecting barrel through the filtration connecting tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 It is a schematic structural diagram of the main body of the dialysis filter for producing sericin protein according to the utility model;

[0016] Figure 2 It is a schematic structural diagram of the side section of a dialysis filter cartridge of a dialysis filter machine for producing sericin protein according to the utility model;

[0017] Figure 3 It is a schematic diagram of the side cross-section structure of the peristaltic hose pump of the dialysis filter for producing sericin protein according to the utility model;

[0018] Figure 4 This is a schematic diagram of the front cross-section structure of a peristaltic hose pump of a dialysis filter for producing sericin according to the utility model.

[0019] In the figure: 1. connecting base; 2. dialysate storage barrel; 21. fixing ring; 22. dialysate replenishing tube; 3. peristaltic hose pump; 31. liquid inlet connecting sleeve; 32. liquid outlet connecting sleeve; 33. liquid delivery pump core; 331. extrusion liquid delivery wheel; 34. infusion hose; 35. pump body motor; 4. dialysis filter cartridge; 41. liquid outlet pipe; 42. filter connecting pipe; 43. gelatin channel; 44. dialysis membrane; 5. liquid delivery pump; 51. liquid extraction pipe; 52. dialysate delivery pipe; 6. waste liquid collection barrel; 61. waste liquid connecting pipe; 7. glue barrel; 71. glue replenishment pipe; 72. liquid inlet pipe; 8. glue protein collection barrel. DETAILED DESCRIPTION

[0020] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0021] See also Figures 1 to 4 The utility model provides a technical solution: a dialysis filter for producing sericin protein, comprising a connecting base 1, a peristaltic hose pump 3 and a dialysis filter cartridge 4, a top side of the connecting base 1 is connected to a dialysis fluid storage barrel 2, and the peristaltic hose pump 3 is connected to the top of the dialysis fluid storage barrel 2, one side of the peristaltic hose pump 3 is provided with a liquid inlet connecting sleeve 31 and a liquid outlet connecting sleeve 32, a liquid inlet connecting sleeve 31 is connected with a liquid inlet pipe 72, and the end of the liquid inlet pipe 72 away from the peristaltic hose pump 3 is connected with a glue barrel 7, a top of the glue barrel 7 is connected with a supplementary glue pipe 71, a side of the dialysis fluid storage barrel 2 is connected with a dialysis fluid replenishment pipe 22, and a side of the dialysis fluid storage barrel 2 away from the dialysis fluid replenishment pipe 22 is connected with a fixed collar 21, the dialysis filter cartridge 4 is connected in the fixed collar 21, and a waste liquid collection barrel 6 is provided on the side of the dialysis filter cartridge 4 away from the dialysis fluid storage barrel 2.

[0022] Each device for dialysis filtration of sericin protein is connected to the connection base 1. Dialysis fluid for precipitating impurities in sericin protein liquid is placed in the dialysis fluid storage barrel 2, and the dialysis fluid in the dialysis fluid storage barrel 2 can be replenished with dialysis fluid through the dialysis fluid replenishment tube 22. The dialysis filter cartridge 4 is connected to the dialysis fluid storage barrel 2 through the fixed collar 21. The sericin protein liquid that needs to be dialysis filtered is added to the sericin liquid barrel 7 through the replenishing sericin liquid tube 71, and then the peristaltic hose pump 3 draws the sericin protein liquid in the sericin liquid barrel 7 into the pump body through the liquid inlet pipe 72, and transports it to the dialysis filter cartridge 4. The waste liquid collection barrel 6 is used to collect the discharged waste liquid.

[0023] A liquid outlet pipe 41 is connected between the liquid outlet connecting sleeve 32 and the dialysis filter cartridge 4, a gelatin collecting bucket 8 is provided below the dialysis filter cartridge 4, and a filter connecting pipe 42 is connected between the gelatin collecting bucket 8 and the dialysis filter cartridge 4, a gelatin channel 43 is provided in the dialysis filter cartridge 4, and a dialysis membrane 44 is connected to the outside of the gelatin channel 43, a waste liquid connecting pipe 61 is connected between the dialysis filter cartridge 4 and the waste liquid collecting bucket 6, a dialysate delivery pipe 52 is connected below the waste liquid connecting pipe 61, a liquid delivery pump 5 is connected to the end of the dialysate delivery pipe 52 away from the dialysis filter cartridge 4, and a liquid extraction pipe 51 is connected between the liquid delivery pump 5 and the dialysis liquid storage bucket 2, and a peristaltic hose pump The sericin liquid is sent into the dialysis filter cartridge 4 through the liquid outlet connection sleeve 32 and the liquid outlet pipe 41, and the sericin liquid enters the gel-sericite channel 43. At the same time, the dialysate in the dialysate storage tank 2 is sent into the dialysis filter cartridge 4 through the dialysate delivery pipe 52 through the liquid extraction pipe 51 by the liquid delivery pump 5, and the sericin liquid enters the gel-sericite channel 43 and is dialyzed and filtered through the outer dialysis membrane 44, and the impurities in the sericin liquid enter the waste liquid connection pipe 61, and the waste liquid is discharged into the waste liquid collection barrel 6 through the waste liquid connection pipe 61, and the sericin filtered by the dialysis filter cartridge 4 is sent into the gel-sericite collection barrel 8 through the filtration connection pipe 42.

[0024] A pump body motor 35 is connected to one side of the peristaltic hose pump 3. A liquid delivery pump core 33 is arranged at the center of the peristaltic hose pump 3, and the liquid delivery pump core 33 is connected to the pump body motor 35. Both sides of the liquid delivery pump core 33 are connected to extrusion delivery wheels 331. An infusion hose 34 is arranged in the peristaltic hose pump 3, and both ends of the infusion hose 34 are respectively connected to the liquid inlet connecting sleeve 31 and the liquid outlet connecting sleeve 32, and the infusion hose 34 is tangent to the two sets of extrusion delivery wheels 331 respectively. The pump body motor 35 drives the liquid delivery pump core 33 to rotate, and the extrusion delivery wheels 331 on both sides of the liquid delivery pump core 33 squeeze the infusion hose 34. Through the unidirectional rotation of the liquid delivery pump core 33, the extrusion delivery wheels 331 transport the liquid in the infusion hose 34 from the liquid inlet connecting sleeve 31 to the liquid outlet connecting sleeve 32, thereby avoiding the destruction of the tissue structure of the sericin protein liquid in the process of pumping, and avoiding the reflux of the sericin protein liquid.

[0025] Working principle: When using the dialysis filter machine for sericin production, the sericin liquid to be dialyzed and filtered is first added into the glue barrel 7 through the glue replenishing tube 71, and the dialysate storage barrel 2 is used to place the dialysate, and the dialysate in the dialysate storage barrel 2 can be replenished with the dialysate through the dialysate replenishing tube 22, and then the peristaltic hose pump 3 draws the sericin liquid in the glue barrel 7 into the pump body through the liquid inlet tube 72, and delivers the sericin liquid into the dialysis filter cartridge 4 through the liquid outlet connecting sleeve 32 and the liquid outlet tube 41.

[0026] The pump motor 35 drives the liquid delivery pump core 33 to rotate, and the liquid delivery wheels 331 on both sides of the liquid delivery pump core 33 squeeze the infusion hose 34. Through the unidirectional rotation of the liquid delivery pump core 33, the liquid delivery wheels 331 transport the liquid in the infusion hose 34 from the liquid inlet connecting sleeve 31 to the liquid outlet connecting sleeve 32, thereby preventing the sericin liquid from damaging the tissue structure in the sericin liquid during the pumping process and preventing the sericin liquid from flowing back.

[0027] The sericin liquid enters the gelatin channel 43, and at the same time, the dialysate in the dialysate storage barrel 2 is sent to the dialysis filter cartridge 4 through the dialysate delivery pipe 52 by the liquid delivery pump 5 via the liquid extraction pipe 51. The sericin liquid enters the gelatin channel 43 and is dialyzed and filtered through the outer dialysis membrane 44. Impurities in the sericin liquid enter the waste liquid connecting pipe 61, and the waste liquid is discharged into the waste liquid collecting barrel 6 by the waste liquid connecting pipe 61. The sericin filtered by the dialysis filter cartridge 4 is sent to the gelatin collecting barrel 8 through the filtration connecting pipe 42.

Claims

1. A dialysis filter for producing sericin, comprising a connection base (1), a peristaltic hose pump (3) and a dialysis filter cartridge (4), characterized in that: A dialysate storage barrel (2) is connected to one side of the top of the connection base (1), and the peristaltic hose pump (3) is connected to the top of the dialysate storage barrel (2). A liquid inlet connection sleeve (31) and a liquid outlet connection sleeve (32) are provided on one side of the peristaltic hose pump (3). A liquid inlet pipe (72) is connected inside the liquid inlet connection sleeve (31), and an end of the liquid inlet pipe (72) away from the peristaltic hose pump (3) is connected to a glue barrel (7). The top of the glue barrel (7) is connected to a replenishing glue tube (71), one side of the dialysate storage barrel (2) is connected to a dialysate infusion tube (22), and the side of the dialysate storage barrel (2) away from the dialysate infusion tube (22) is connected to a fixing ring (21), the dialysate filter cartridge (4) is connected in the fixing ring (21), and the side of the dialysate filter cartridge (4) away from the dialysate storage barrel (2) is provided with a waste liquid collection barrel (6).

2. The dialysis filter for producing sericin according to claim 1, characterized in that: A liquid outlet pipe (41) is connected between the liquid outlet connecting sleeve (32) and the dialysis filter cartridge (4), a gelatin collection bucket (8) is provided below the dialysis filter cartridge (4), and a filtration connecting pipe (42) is connected between the gelatin collection bucket (8) and the dialysis filter cartridge (4).

3. The dialysis filter for producing sericin according to claim 2, characterized in that: The dialysis filter cartridge (4) is provided with a gelatin channel (43), and the outer side of the gelatin channel (43) is connected to a dialysis membrane (44), and a waste liquid connecting pipe (61) is connected between the dialysis filter cartridge (4) and the waste liquid collection bucket (6).

4. The dialysis filter for producing sericin according to claim 3, characterized in that: A dialysate delivery pipe (52) is connected below the waste liquid connection pipe (61), and a liquid delivery pump (5) is connected to one end of the dialysate delivery pipe (52) away from the dialysate filter cartridge (4), and a liquid extraction pipe (51) is connected between the liquid delivery pump (5) and the dialysate storage barrel (2).

5. The dialysis filter for producing sericin according to claim 1, characterized in that: One side of the peristaltic hose pump (3) is connected to a pump body motor (35), a liquid delivery pump core (33) is arranged at the center of the peristaltic hose pump (3), and the liquid delivery pump core (33) is connected to the pump body motor (35), and both sides of the liquid delivery pump core (33) are connected to extrusion liquid delivery wheels (331).

6. The dialysis filter for producing sericin according to claim 5, characterized in that: The peristaltic hose pump (3) is provided with an infusion hose (34), and the two ends of the infusion hose (34) are respectively connected to the liquid inlet connecting sleeve (31) and the liquid outlet connecting sleeve (32), and the infusion hose (34) is respectively tangent to the two sets of extrusion liquid delivery wheels (331).

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