Pipetting and clamping combined module and automatic processing module
By designing a pipetting combination module containing independent drive span beams and cooperative mechanisms, the problem of modular isolation difficulty and high contamination risk in automated sample processing systems is solved, and efficient pipetting and clamping operations are achieved, reducing the contamination risk.
Patent Information
- Application Number
- CN202421778872.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-25
- Publication Date
- 2025-05-06
- Estimated Expiration
- 2034-07-25
AI Technical Summary
In the prior art, the modular isolation of an automated sample processing system is difficult, resulting in a high risk of pollution, and the pollution risks are different at different treatment stages, and the shared robotic arms leads to a higher risk of system pollution.
A pipetting clamping combination module is designed, including a first span beam and a second span beam. The independent driving movement of the span beam is achieved by using a common extension guide rail and an extension guide rod, and combined with the common substrate and slide rail in the cooperative mechanism, the independent up and down movement of the pipetting unit and the clamping unit is realized.
The efficient collaboration between the pipetting unit and the clamping unit is achieved, reducing the risk of contamination in the system, and improving the compactness and functional diversity of the modular design.
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Figure CN222829691U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of medical equipment, and particularly relates to a liquid transfer clamping combination module and an automatic processing module. Background Art
[0002] In the medical field, the analysis and processing of samples often requires a relatively cumbersome process. In the past when automation technology was not developed, processes related to sample processing and analysis basically required manual participation to execute processing and circulation. This requires the upgrading of basic health-related equipment such as specialized laboratories, so the cost and demand for specialized testing capabilities will be very high. With the development of integrated automation technology, the development of streamlined sample processing systems can meet the growing demand for health testing and explosive growth in disease diagnosis. This system automatically realizes the transfer of samples, reaction reagents, detection reagents, and consumables using separate functional modules or composite functional modules. The most important thing is to automatically mix the reagents with the target-containing liquid in a certain reaction container at each stage to construct a reaction system. Meeting this demand depends on the design of integrated pipetting units and clamping units.
[0003] The operations required in different automated equipment are complex and diverse, and in response to the diverse operational requirements, different companies have developed different automatic processing modules to meet the requirements. Patent CN104138772B authorizes a method and device for capping containers for biological samples. Its essence is a single-function rotating or pulling clamping mechanism, which can rely on the clamping unit contained in the mechanism to take the tube cover of the object to be operated, and then transfer it to the storage area carrying different types of sample tubes or reagent tubes through the drive of the driving mechanism to complete the loading of the tube cover. In the scheme authorized by U.S. Patent US6656724B1, the pipetting unit and the plate-type consumables transfer unit are integrated on the same robotic arm and distributed on both sides of the width direction of the robotic arm. Here, the pipetting unit includes two different types of pipetting units, high-precision and low-precision. This integrated design can realize operations such as cleaning of trace reaction liquids, larger amounts of reagents, pipetting units, and transfer of plate-type consumables. In the solution disclosed in patent application CN103657754A, the liquid transfer robot arm can drive the pipette configured therein, and can complete the function of transferring reagents or reaction solutions in different well units of the consumables in the integrated consumables, while the liquid transfer robot arm here exists as an independent functional module, and does not involve the idea of integration. In most cases in the prior art, the integration is not very high. For batch continuous sample processing systems, the transfer requirements of consumables, reagents, etc. that need to be executed are more and more complicated. In the prior art, a 360° flexible robot arm structure is introduced into the batch sample processing system, but this involves itself with high complexity, the layout space required by the robot arm is large, and different transfer operations need to be arranged in a centralized manner. This makes it difficult to modularize and isolate the system itself, and different processes in the sample processing operation actually have different contamination risks. Sharing a robot arm for processes with higher and lower contamination risks will lead to a higher contamination risk for the system. From the perspective of application scenarios and structural designs, the various robotic arms analyzed above have relatively simple functions and overly complex designs, and have different pollution level requirements for the use space and operation area. Therefore, it is necessary to design a pipetting and transfer collaboration module suitable for the flow module.
[0004] Since the multifunctional collective pipetting and clamping combination collaborative modules suitable for different modules need to be adapted to different application scenarios, the targeted design of adaptive collaborative modules is a direction that needs to be optimized urgently. Utility Model Content
[0005] In order to solve the above problems existing in the prior art, the purpose of the utility model is to provide a pipetting and clamping combination module and an automated processing module including the same.
[0006] The technical solution adopted by the utility model is:
[0007] A pipetting clamping combination module, characterized in that: it comprises a first span beam and a second span beam, and a consumable clamping unit with a preset matching width range is configured on one side of the first span beam in the width direction; a cooperation mechanism is also configured on the same side of the second span beam in the width direction as the consumable clamping unit configured in the width direction of the first span beam, and the cooperation mechanism includes a tubular clamping unit and a first quantity pipetting unit; it also includes a common extension guide rail and an extension guide rod, one end of the first span beam in the length direction and one end of the second span beam in the length direction are both slidably connected to the common extension guide rail, and the other end of the first span beam in the length direction and the other end of the second span beam in the length direction are both connected to the extension guide rod.
[0008] As a preferred solution of the utility model, a consumable slide rail and a consumable transmission mechanism extending along the length direction of the first span beam are arranged on the opposite side of the consumable clamping unit arranged in the width direction of the first span beam; and a cooperative slide rail and a cooperative transmission mechanism extending along the length direction of the second span beam are arranged on the opposite side of the cooperative mechanism arranged in the width direction of the second span beam.
[0009] As a preferred embodiment of the present invention, the cooperative mechanism includes a common substrate, on which is disposed a tube clamping slide rail slidably connected to the tubular clamping unit and a pipetting slide rail slidably connected to the first number of pipetting units, and the tube clamping slide rail and the pipetting slide rail are located on the same side of the common substrate.
[0010] An automated processing module comprises a first operating area and a second operating area; a common extension guide rail and an extension guide rod are arranged in the longitudinal direction of the module, and the first span beam and / or the second span beam can be driven to move in the first operating area; a sample tube operating module is also arranged in the adjacent area in the longitudinal direction, and at least some submodules of the sample tube operating module can be driven to move in the second operating area.
[0011] As a preferred solution of the present utility model, the projection area of the second operating area in at least one horizontal plane includes a sub-area not covered by the projection area of the first operating area.
[0012] As a preferred solution of the present utility model, the sample tube operation module includes a third span beam that is parallel to the first span beam and / or the second span beam and is fixedly arranged.
[0013] As a preferred solution of the utility model, a switch cover operating substrate is connected to one side of the third span beam in the width direction, and a pipe clamping transfer module is arranged on the other side of the third span beam in the width direction.
[0014] As a preferred solution of the utility model, the switch cover operating base plate includes a plurality of switch cover slide rails arranged at intervals, and a corresponding number of switch cover units can be independently driven to be slidably connected with the switch cover slide rails.
[0015] As a preferred solution of the present invention, the pipe clamping and transferring module includes a clamping extension beam arranged in the depth direction of the module.
[0016] As a preferred solution of the utility model, the length of the clamping extension beam in the module depth direction does not exceed 1 / 3 of the length of the common extension guide rail and the extension guide rod.
[0017] The beneficial effects of the utility model are:
[0018] 1. The combined module of the utility model comprises a first span beam and a second span beam, one of the two ends in the length direction of the two span beams is connected to a common extension guide rail, and the other end is connected to an extension guide rod, and the two span beams can be driven to move back and forth along the extension direction of the guide rail and the guide rod through an independent drive. In order to ensure that the pipetting unit and the clamping unit driven by the span beams have sufficient and reliable avoidance space, the pipetting unit and the different clamping units are arranged on the same side in the width direction of the two span beams, and the other side opposite thereto is arranged along the extension direction of the span beam length. A transmission mechanism that can drive the pipetting unit and the clamping unit to move is also arranged, which also makes the control simpler to implement; the pipetting unit and the clamping unit in the cooperative mechanism share a substrate, and spaced-apart pipetting slide rails and tube clamping slide rails are arranged on the common substrate, so that the two can be independently driven to rise or fall through an independent Z-axis drive.
[0019] 2. The automated processing module of the utility model comprises a common extension rail and an extension guide rod extending a first length in the depth direction, the first span beam and / or the second span beam can be driven to move in the first operating area, and a sample tube operation module is also arranged in the adjacent area in the depth direction, and at least some submodules of the sample tube operation module can be driven to move in the second operating area, thereby realizing a layout design for arranging more functional modules, the sample tube operation module also comprises a third span beam fixedly arranged and parallel to the first span beam and the second span beam, and the projection area of the second operating area in at least one horizontal plane includes a subarea not covered by the projection area of the first operating area, It is ensured that the movement of the first span beam and the second span beam will not be interfered by the third span beam. The switch cover operation module and the tube clamping transfer module are connected to both sides of the width direction of the third span beam, thus maximizing the use of the remaining space in the depth direction to ensure the compactness of the system layout. At the same time, the length of the clamping extension beam configured in the depth direction of the tube clamping transfer module does not exceed 1 / 3 of the length of the shared extension guide rail and the extension guide rod. This ensures that the first span beam and the second span beam have sufficient driven movement stroke, realizing a collective design with more functions and more reagent storage, and also ensuring that the compactness of the tube clamping transfer module design will not waste too much space, and the risk of operation interference between different modules is smaller. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] Figure 1 It is a structural diagram of the pipetting and clamping combination module driven by two span beams provided in this application;
[0021] Figure 2 is a diagram of a cooperative mechanism including a tubular clamping unit and a first number of pipetting units provided in the present application;
[0022] Figure 3 It is a layout diagram of the consumable clamping unit provided in this application;
[0023] Figure 4 It is a partial structural diagram of the automated processing module including the combined module provided in the present application;
[0024] Figure 5 This is a first-direction structural diagram of a sample tube operation module with a fixed third span beam provided in the present application;
[0025] Figure 6 This is a second direction structural diagram of the sample tube operation module with a fixed third span beam provided in the present application. DETAILED DESCRIPTION
[0026] In order to make the purpose, technical scheme and advantages of the embodiments of the utility model clearer, the technical scheme in the embodiments of the utility model will be clearly and completely described below in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are part of the embodiments of the utility model, not all of the embodiments. Generally, the components of the embodiments of the utility model described and shown in the drawings here can be arranged and designed in various different configurations.
[0027] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely represents selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in the field without creative work are within the scope of protection of the present invention. It should be noted that the embodiments of the present invention and the features in the embodiments can be combined with each other without conflict.
[0028] As described in the background technology, in an automated sample processing system with a high batch processing capacity, it is a more reasonable design to design the system as a multi-modular structure according to different functional requirements such as sample addition, sample processing, system configuration, reaction detection, etc. This design adapts to the actual scenario characteristics that the sample tubes or operating states of different samples or sample-related solutions have different opening states at different processing stages, so the contamination risks of each module are different. However, this modular design uses flexible robotic arms with complex functions, which have problems such as high cost and limited space. Therefore, it is very necessary to design a multifunctional combination module for pipetting and clamping that is suitable for different modules of the assembly line.
[0029] Figure 1It is a structural diagram of the pipetting and clamping combination module driven by two span beams provided by the utility model. In various types of biological related diagnosis and detection, considering the risk of contamination and the requirements for the construction of the reaction system, it is very necessary to design a collaborative processing module with a high degree of integration in the batch processing system. In the present application, two span beams that can be driven independently are designed, wherein the first span beam 10 can be driven by the first span beam drive motor 411; the second span beam 20 can be driven by the second span beam drive motor 421. Here, the two drive motors can drive the two span beams respectively through two independent span beam transmission mechanisms. The transmission mechanism is optimally configured as a pulley drive, so that a reliable and low-cost driving effect can be achieved. Here, the two independent span beams have two opposite ends in the length direction, one of which is connected to the common extension rail 401. Here, the two span beams are connected to the common extension rail 401 by a connecting block, and the connecting block can also be directly or indirectly connected to the span beam transmission mechanism, so that the two span beams can be driven by the span beam drive motor to slide back and forth along the extension direction of the common extension rail 401. The other end of the span beam in the length direction is connected to the first roller group 403 and the second roller group 404 respectively. Any roller group here includes two independent rollers, and the configuration of the rollers can make the span beam rollingly connected to the extension guide rod 402, so that the span beam driving motor drives the span beam to run reliably with low resistance along the extension direction of the common extension guide rail 401. Of course, the common extension guide rail 404 and the extension guide rod are configured to make their extension directions parallel. In this embodiment, the width direction of the two span beams is configured with a pipetting unit and a clamping unit, so that different functional units can perform different functional operations within a partial timing. One side of the width direction of the first span beam 10 is configured with a consumable clamping unit 110 with a preset matching width range. The preset width range of the consumable clamping unit 110 here is determined according to the width of the clamped consumable, and it is optimally configured to be 0.75-1.25 times the width of the clamped consumable. The held consumables may include standard deep-well plate extraction consumables, so that the clamping operation of the consumable clamping unit 110 can be ensured to be faster and the control method is simple and efficient. On the same side of the width direction of the second span beam 20 as the first span beam 10 where the consumable clamping unit 110 is configured, there is a collaborative mechanism including a tubular clamping unit 210 and a first number of pipetting units 220. The number of pipetting units 220 here is 1, and the consumable clamping unit 110 and the collaborative module composed of the tubular clamping unit 210 and the pipetting unit 220 are respectively configured on the same side in the width direction of the two span beams, so that the avoidance space between the two span beams is consistent when the two span beams are driven to move, and the avoidance control is simple, and the two span beams can be configured to the required area without hindrance under rapid control to perform pipetting or transfer operations.In order to meet the needs of efficient and fast pipetting, the number of pipetting units can be configured to be 2 or more. Here, the tube clamping unit 210 and the consumable clamping unit 110 can be selected as the same type, with only the difference in the clamping claw part. Both can have a rotation function, which can realize the preset angle of rotation of the clamped tube or consumable, meeting the needs of opening and closing the cover and adjusting the position of the consumables.
[0030] Figure 2 : This is a diagram of a cooperative mechanism provided by the present application, including a tubular clamping unit 210 and a first number of pipetting units 220. A cooperative mechanism is arranged on the second span beam 20, wherein the cooperative mechanism includes a common substrate, and the common substrate is provided with a pipetting slide rail 223 and a tube clamping slide rail 214 at a preset interval, and the pipetting unit 220 and the tubular clamping unit 210 can be connected with the interval slide rails by different connecting blocks. The cooperative mechanism includes a tube clamping drive motor 211, whose output shaft is connected to a transmission screw 212, and the transmission screw 212 is threadedly connected to a connecting block provided with a transmission nut 213. When the tube clamping drive motor 211 outputs a clockwise or counterclockwise rotational motion, the transmission of the threaded transmission mechanism through the screw nut can be converted into a high-precision up and down sliding motion of the tubular clamping unit 210. The pipetting drive motor 221 can be arranged on the other side of the common substrate to ensure that the entire cooperative mechanism is more compact. The pipetting drive motor 221 can output a rotational drive, which is then transmitted through the pipetting transmission mechanism 222, to convert the clockwise or counterclockwise rotational motion into a reciprocating sliding motion that drives the pipetting unit 220 to slide up and down along the pipetting guide rail 223. In this way, the pipetting unit 220 can drive the pipetting consumables connected to the pipetting tip 2201 to transfer the target solution or related reagents between different containers. Figure 2 b shows the cooperative transmission mechanism configured at the other end opposite to the second span beam 20. In this embodiment, a cooperative drive motor 231 is configured at the top of the span beam width direction, and a corresponding drive circuit board and a corresponding heat dissipation component are configured in its upper area. The output shaft of the cooperative drive motor 231 is connected to a cooperative transmission driving wheel 232, and a cooperative transmission driven wheel is configured at a preset distance along the length direction of the second span beam 20, and a cooperative transmission belt 233 is configured between the driving wheel and the driven wheel, so as to form a cooperative transmission mechanism that can transmit cooperative drive rotational motion. At the same time, a cooperative slide rail 234 is configured along the length direction of the second span beam 20, and the cooperative connection block 235 can be connected to the cooperative slide rail 234 in an engaging manner, and it is also directly or indirectly fixedly connected to the cooperative transmission belt 233 and the common substrate, so that when the cooperative drive motor 231 rotates clockwise or counterclockwise, the cooperative module can be driven to slide back and forth along the cooperative slide rail 234 through the cooperative transmission mechanism. Here, the cooperative base plate itself cannot be driven to move up and down, which ensures that the movement reliability of the pipetting unit 220 and the tubular clamping unit 210 configured on the cooperative module is higher.
[0031] Figure 3 It is a layout structure diagram of the consumable clamping unit 110 provided in the present application. Only one side of the width direction of the first span beam 10 is configured with the consumable clamping unit 110. Here, in order to ensure that the consumable clamping claw has a longer height travel range, the consumable clamping unit 110 is configured as a folding travel structure, and the consumable clamping drive motor 111 is connected to the folding transmission structure. The folding transmission structure includes a first transmission structure, a second transmission structure, a base, a guide member and a clamping claw guide rod configured on the consumable substrate, wherein the guide member is movably connected to the base. The first transmission structure can drive the guide member to move along the length direction of the guide member, the clamping claw guide rod is superimposed on the guide member and movably connected to the guide member, and the protruding end of the clamping claw guide rod is provided with the consumable clamping unit 110. In order to ensure that the first transmission structure of the folding travel transmission structure is also configured with a power-off protection unit 113 in the case of power failure. Here, the power-off protection unit 113 is optimally connected to the driven wheel of the first transmission structure. The guide rod can be fixedly connected to the first transmission pulley 112 through the first connecting block. The clamping claw guide rod is fixedly connected to the second transmission belt in the second transmission structure through the second connecting block, and the other end of the second transmission belt is connected to the base through the third connecting block. In this way, when the clamping drive motor 111 rotates clockwise or counterclockwise, the folding transmission structure can drive the consumable clamping unit 110 connected to the clamping claw guide rod to achieve a longer stroke up and down reciprocating motion. The end of the consumable clamping unit 110 is configured with a first consumable clamping claw 1101 and a second consumable clamping claw 1102 that can move closer to or away from each other. The two can be driven to adjust the relative distance between the two within a preset width range, thereby clamping or loosening the transfer object. Similarly, a consumable drive motor 241 is configured at the top of the first span beam 10 in the width direction, and a drive plate and a drive radiator are also configured above it. The other side that is laterally opposite to the consumable clamping unit 110 is also configured with a consumable transmission structure and a consumable slide rail extending along the length direction of the second storage. The transmission structure and the consumable slide rail are connected to the consumable drive motor 241. Figure 2 The structure of b is similar and will not be repeated here.
[0032] Figure 44 is a partial structural diagram of an automated processing module including a combined module provided by the present application. A common extension rail 401 and an extension guide rod 402 extending a first length are arranged in the depth direction of the automated processing module. The first span beam 10 and / or the second span beam 20 can be driven to move in the first operating area. A sample tube operation module is also arranged in the adjacent area in the depth direction, and at least part of the submodules of the sample tube operation module can be driven to move in the second operating area. Here, the sample tube operation module includes a third span beam 30 fixed in the module. In this embodiment, the configuration height of the fixed span beam is lower than that of the first span beam 10 and the second span beam 20, and the length direction of the third span beam 30 is arranged parallel to the length direction of the first span beam 10 and the second span beam. In this way, the first span beam 10 and the second span beam 20 are almost not disturbed by the third span beam 30 when they are driven to move, and there is no need to reserve too much avoidance space. The parallel arrangement of different span beams can also enable the various processing units arranged thereon to perform different operations on similar working surfaces, and the control method of different processing units is also simpler and more reliable. A tube clamping and transferring module 32 is disposed on one side of both sides of the third span 30 in the width direction, which can clamp and transfer sample tubes from the sample tube transfer track 504 at the end of the automated processing module in the depth direction. The other end of the automated processing module in the depth direction is also configured with a reagent storage area 501, a transmission channel configuration area 502, a stirring sleeve loading area 503, etc. The first span 10 and the second span 20 can be driven to perform consumable transfer in different areas. In this embodiment, the projection area of the second operation area in at least one horizontal plane includes a sub-area not covered by the projection area of the first operation area, that is, the tube clamping and transferring unit 320 in the tube clamping and transferring module 32 can be driven to perform the clamping and transferring operation of the sample tube in the area not covered by the first span 10 and the second span 20. In this way, on the one hand, the sample tube operation module can have an independent operation area and is not affected by the previous transfer operation. The submodules such as the tube clamping and transferring module 32 can also simultaneously perform operations such as the transfer, opening and closing cover scanning and identification of the sample tube, thereby ensuring the maximum collection design of different functions in the automated processing module, and different operations in the two areas can also be realized almost without interference and run simultaneously.
[0033] Figure 5 and Figure 6 This is a structural diagram of a sample tube operation module with a fixed third span provided by the present application. The third span beam 30 is fixedly connected to the automated processing module using two opposite span beam fixing plates 301 and 302. The third span beam 30 is fixedly configured so that the processing units configured thereon will not interfere with the processing units configured on the moving first span beam 10 and second span beam 20, and the operation drive timing of the processing units on different span beams can be reasonably allocated. The sample tube switch cover module 31 and the tube clamping transfer module 32 are respectively configured on the two sides in the width direction of the third span beam 30. Figure 5The structure diagram of the sample tube switch cover module 31 arranged on one side is illustrated, and two switch cover units 311 and 312 are arranged on the configuration side, and the two switch cover units are arranged on the switch cover operation substrate. The output shaft of the switch cover drive motor 3111 is connected to the switch cover transmission screw 3112, and the switch cover transmission screw 3112 is threadedly connected to the switch cover connection block 3113. The first switch cover unit 311 is arranged on the first switch cover side plate 3114 connected to the third span beam 30. Here, a first switch cover slide rail can be arranged on the first switch cover side plate 3114, and the first switch cover unit 311 is directly or indirectly engaged and connected thereto. The switch cover connection block 3113 is also connected to the first switch cover unit 311, so that when the switch cover drive motor rotates clockwise or counterclockwise, the first switch cover unit 311 can reciprocate up and down along the first switch cover slide rail. Here, configuring the switch cover unit on the side plate of the switch cover can maintain a certain distance between the switch cover clamp and the cross beam 30, which can reduce the risk of interference with the switch cover operation and reserve enough space to configure the process monitoring sensor to make the system run more reliable. Another switch cover unit configuration is similar and will not be repeated here. In this way, a number of switch cover slide rails arranged at intervals enable a corresponding number of switch cover units to be independently driven and slidably connected to the switch cover slide rails. Of course, in order to improve the efficiency of the switch cover, a larger number of switch cover units can be configured here, and a corresponding number of tube body fixing units 510 are configured on the mounting base of the cross beam fixing plate for the corresponding switch cover units. The tube fixing unit 510 includes opposite fixed jaws, which can clamp and fix the sample tube body transferred thereto, and a tube fixing slide rail 515 is also arranged on the base. The output shaft of the tube fixing driving motor 511 is connected to the tube fixing driving wheel 512, and a tube fixing driven wheel is arranged at a preset distance, and a tube fixing transmission belt 513 is sleeved between the two, and a tube fixing connecting block is arranged on the tube fixing transmission belt 513, which is connected to the tube fixing unit. In this way, when the tube fixing driving motor 511 rotates clockwise or counterclockwise, the tube fixing unit can be driven to slide along the tube fixing slide rail 515 to different positions through the tube fixing transmission structure, such as the sample tube can be opened and closed at the position close to the opening and closing cover unit. And the sample liquid can be transferred in cooperation with the liquid transfer unit arranged on the second span beam 20 at a distance, so that the movement of the tube fixing unit ensures that different operations can be carried out efficiently without interference. Figure 6The structure diagram of the tube clamping transfer module 32 configured on the other side of the switch cover module side in the width direction of the third span is illustrated. Here, since the tube clamping transfer module 32 needs to perform functions such as clamping, transferring, scanning, etc. of sample tubes at different positions, it needs to be driven to operate within the second stroke range. In order to ensure its operating range, a tube clamping transfer slide 303 is configured in the length direction of the third span. Of course, a tube clamping transfer drive motor and a tube clamping transfer transmission mechanism are also configured, and the clamping extension beam 305 can be connected to the tube clamping transfer slide 303 through the tube clamping transfer connection block 304. In this way, the tube clamping transfer motor can drive the clamping extension beam 305 to slide back and forth along the extension direction of the tube clamping transfer slide 303. The clamping extension beam 305 extending a preset length along the depth direction of the module has a length not exceeding 1 / 3 of the length of the common extension rail and extension guide rod connected to the first span and the second span, which also ensures that the first span and the second span have sufficient movement stroke. The length of the clamping extension beam 305 here should not be shorter than 1 / 6 of the length of the common extension rail and the extension guide rod, so as to ensure that the pipe clamping transfer unit 320 has sufficient operating space. The design of its driving and transmission mechanism is also simpler and more reliable. An extension slide rail 334 is arranged in the length direction of the clamping extension beam 305, and the output shaft of the extension drive motor 331 is connected to the extension driving wheel 332, and the extension driven wheel is arranged at a preset interval, and the extension transmission belt 333 is sleeved between the two, and the clamping transfer base plate equipped with the pipe clamping transfer unit 320 can be slidably connected to the extension slide rail 334 in an embedded manner. In this way, the extension drive motor 331 can drive the clamping transfer substrate to slide back and forth along the length direction of the extension slide rail. A clamping transfer vertical slide rail 326 is arranged on the clamping transfer substrate, which is connected to the tube clamping transfer unit 320 in an interlocking manner. The output shaft of the clamping transfer vertical drive motor 321 is connected to a clamping transfer vertical active wheel 322, and a clamping transfer vertical driven wheel 324 is arranged at a preset interval in the vertical direction of the clamping transfer substrate. A clamping transfer vertical transmission belt 323 is sleeved between the two, and a clamping transfer vertical connecting block 325 is fixedly connected to the transmission belt. At the same time, the connecting block is also connected to the tube clamping and transferring unit 320, so that the clamping and transferring vertical driving motor 321 can drive the tube clamping and transferring unit 320 to reciprocate vertically, and cooperate with the adjustment of the position of the tube body fixing unit 510, so that the tube clamping and transferring unit 320 can clamp the sample tube in the sample tube rack transmission part to the tube body fixing unit 510. After completing the transfer of the sample tube, the tube body fixing unit 510 can change its position to perform operations such as opening and closing the cover of the sample tube and transferring the sample liquid. Here, the tube clamping and transferring unit 320 can be driven to perform different operations within the second stroke range, such as transferring the sample tube, scanning and identifying the sample tube, and so on.
[0034] The present utility model is not limited to the above-mentioned optional implementation modes. Anyone can derive other various forms of products under the inspiration of the present utility model. However, no matter what changes are made in the shape or structure, all technical solutions that fall within the scope defined by the claims of the present utility model fall within the protection scope of the present utility model.
Claims
1. A pipetting and clamping assembly module, characterized in that: It includes a first span beam and a second span beam, and a consumable clamping unit with a preset matching width range is configured on one side of the width direction of the first span beam; a cooperation mechanism is also configured on the same side of the width direction of the second span beam as the consumable clamping unit configured in the width direction of the first span beam, and the cooperation mechanism includes a tubular clamping unit and a first quantity pipetting unit; it also includes a common extension rail and an extension guide rod, one end of the first span beam in the length direction and one end of the second span beam in the length direction are both slidably connected to the common extension guide rail, and the other end of the first span beam in the length direction and the other end of the second span beam in the length direction are both connected to the extension guide rod.
2. The liquid transfer and clamping assembly module according to claim 1, characterized in that: On the opposite side of the consumable clamping unit in the width direction of the first span beam, there are configured a consumable slide rail and a consumable transmission mechanism extending along the length direction of the first span beam; on the opposite side of the cooperation mechanism in the width direction of the second span beam, there are configured a cooperation slide rail and a cooperation transmission mechanism extending along the length direction of the second span beam.
3. The liquid transfer and clamping assembly module according to claim 1, characterized in that: The cooperation mechanism comprises a common substrate, on which are arranged a tube clamping slide rail slidably connected to the tube clamping unit and a pipetting slide rail slidably connected to the first number of pipetting units, and the tube clamping slide rail and the pipetting slide rail are located on the same side of the common substrate.
4. An automated processing module comprising the pipetting and clamping assembly module according to claim 1, characterized in that: It includes a first operating area and a second operating area; a common extension guide rail and an extension guide rod are arranged in the depth direction of the module, and the first span beam and / or the second span beam can be driven to move in the first operating area; a sample tube operating module is also arranged in the adjacent area in the depth direction, and at least some sub-modules of the sample tube operating module can be driven to move in the second operating area.
5. The automated processing module according to claim 4, characterized in that: The projection area of the second operating area in at least one horizontal plane includes a sub-area not covered by the projection area of the first operating area.
6. The automated processing module according to claim 4, characterized in that: The sample tube operation module includes a third span beam that is parallel to the first span beam and / or the second span beam and is fixedly arranged.
7. The automated processing module according to claim 6, characterized in that: A switch cover operating substrate is connected to one side of the third span beam in the width direction, and a pipe clamping transfer module is arranged on the other side of the third span beam in the width direction.
8. The automated processing module according to claim 7, characterized in that: The switch cover operating base plate comprises a plurality of switch cover slide rails arranged at intervals, and a corresponding number of switch cover units can be independently driven to be slidably connected with the switch cover slide rails.
9. The automated processing module according to claim 7, characterized in that: The pipe clamping and transferring module comprises a clamping extension beam arranged in the depth direction of the module.
10. The automated processing module according to claim 9, characterized in that: The length of the clamping extension beam in the module depth direction does not exceed 1 / 3 of the length of the common extension guide rail and the extension guide rod.
Citation Information
Patent Citations
Pipette
CN103657754A
A capping device for biological sample containers and a method for capping such containers.
CN104138772B
Apparatus for automatic implementation of chemical or biological methods
US6656724B1