Efficient compound production equipment

Abstract

The utility model discloses efficient compound production equipment and belongs to the technical field of reaction production equipment. Comprising an adjusting platform, a lower reaction tank arranged on the adjusting platform, an upper reaction tank arranged at the upper end of the adjusting platform and distributed opposite to the lower reaction tank, and a weighing box arranged on the adjusting platform, according to the production equipment, the lower reaction tank and the upper reaction tank which are oppositely distributed are close to each other or far away from each other through the hydraulic lifting element, the convenience of cleaning and overhauling work can be improved while normal production work of the medical intermediates is guaranteed, and the working efficiency is improved; according to the medical intermediate weighing device, the liquid outlet valve is opened and closed in time, medical intermediates are discharged and fall into the weighing inner box, meanwhile, the weight of the weighing inner box is detected through the gravity sensor, the production efficiency is improved, waste of the medical intermediates is greatly reduced, the production cost is reduced, and meanwhile the consistency and stability of products are guaranteed.

Description

Technical Field

[0001] The utility model relates to the technical field of reaction production equipment, in particular to a compound high-efficiency production equipment. Background Art

[0002] Pharmaceutical intermediates are actually some chemical raw materials or chemical products used in the process of drug synthesis. This kind of chemical product does not require a drug production license and can be produced in an ordinary chemical plant. As long as it reaches a certain level, it can be used in drug synthesis.

[0003] In the production process of pharmaceutical intermediates, a reactor is usually used in the prior art to stir and synthesize the drugs. The stirring device in the reactor can ensure that the reactants are evenly mixed in the entire reaction system, which is beneficial to improving the reaction rate and the uniformity of the product.

[0004] The existing pharmaceutical intermediate production equipment is inconvenient to clean and repair during use, and the discharge and weighing process of the pharmaceutical intermediates is not accurate and efficient enough, which easily leads to waste of materials. Utility Model Content

[0005] In view of the above problems, the utility model discloses a compound high-efficiency production device.

[0006] The technical solution of the utility model is: a compound efficient production equipment, comprising an adjustment platform, a lower reaction tank arranged on the adjustment platform, an upper reaction tank arranged at the upper end of the adjustment platform and distributed opposite to the lower reaction tank, and a weighing box arranged on the adjustment platform;

[0007] The lower reaction tank is driven to rotate by the first rotating motor, the height of the adjustment platform is adjustable, a liquid outlet valve is arranged on the side wall of the lower reaction tank, and a vertical stirring rod is arranged in the upper reaction tank; the weighing box is connected to one side of the bottom end of the adjustment platform through a placement rack.

[0008] Furthermore, the adjustment platform includes a lower mounting platform, an upper mounting platform located at the upper end of the lower mounting platform, and a hydraulic lifting element for connecting the upper mounting platform and the lower mounting platform. The upper reaction tank is arranged at the lower end of the upper mounting platform, the lower reaction tank is arranged at the upper end of the lower mounting platform, and the placement frame is arranged on one side of the bottom end of the lower mounting platform.

[0009] Description: When the lower reaction tank and the upper reaction tank need to be separated, the upper mounting platform is lifted up through the extension of the hydraulic lifting element to move the upper reaction tank upward, and then the inner walls of the lower reaction tank and the upper reaction tank are cleaned or repaired, which increases the convenience of cleaning and repair work and improves work efficiency.

[0010] Furthermore, a sealing ring is provided at the bottom end of the upper reaction tank, the inner diameter of the sealing ring is larger than the outer diameter of the lower reaction tank, and a plug-in ring is provided at the upper end of the lower reaction tank, and an annular groove matching the size of the plug-in ring is provided at the bottom end of the upper reaction tank.

[0011] Description: When it is necessary to produce pharmaceutical intermediates, the lower reaction tank and the upper reaction tank are brought closer to each other through the compression of the hydraulic lifting element until the plug-in ring at the upper end of the lower reaction tank is inserted into the annular groove at the bottom end of the upper reaction tank. At this time, the connection joint between the lower reaction tank and the upper reaction tank is sealed by the sealing ring, which can ensure the normal production of pharmaceutical intermediates and avoid leakage of reaction liquid or gas, thereby improving the overall working reliability of the reaction equipment.

[0012] Furthermore, the vertical stirring rod is driven to rotate by a second rotary motor, and the length of the vertical stirring rod is equal to the sum of the heights of the lower reaction tank and the upper reaction tank.

[0013] Description: When the raw materials of the pharmaceutical intermediates in the lower reaction tank and the upper reaction tank need to be stirred, the second rotating motor can be used to drive the vertical stirring rod to rotate and stir, which can improve the reaction effect and the production efficiency of the pharmaceutical intermediates. The purpose of limiting the length of the vertical stirring rod to be equal to the sum of the heights of the lower reaction tank and the upper reaction tank is to ensure that the vertical stirring rod can completely cover the height of the entire reaction equipment, thereby achieving effective stirring.

[0014] Furthermore, the weighing box includes a fixed card box arranged at the upper end of the placement rack, and a weighing inner box movably connected to the inner wall of the fixed card box, a gravity sensor is provided at the upper end of the fixed card box, and a lifting handle is provided at the upper end of the weighing inner box.

[0015] Description: When the reaction is completed and the pharmaceutical intermediates in the lower reaction tank and the upper reaction tank need to be quantitatively discharged, the lower reaction tank is driven to rotate by the first rotating motor. When the liquid outlet valve is located at the upper end of the weighing inner box, the liquid outlet valve is opened to discharge the pharmaceutical intermediates and drop them into the weighing inner box. At the same time, the weight of the weighing inner box is detected by the gravity sensor. When the discharged weight of the pharmaceutical intermediates and the weight of the weighing inner box reach the set value, the liquid outlet valve is closed. Then, the weighing inner box can be taken out of the fixed card box by pulling the handle. This not only improves the production efficiency, but also greatly reduces the waste of pharmaceutical intermediates, helps to reduce production costs, and also ensures the consistency and stability of the products.

[0016] Beneficial effects of the utility model:

[0017] The production equipment of the utility model uses a hydraulic lifting element to make the relatively distributed lower reaction tank and upper reaction tank approach or move away from each other, and while ensuring the normal production of pharmaceutical intermediates, it can also increase the convenience of cleaning and maintenance work and improve work efficiency. The connecting seams of the lower reaction tank and the upper reaction tank are sealed by a sealing ring to avoid leakage of reaction liquid or gas, thereby improving the overall working reliability of the reaction equipment; the pharmaceutical intermediate is discharged and falls into the weighing inner box by timely opening and closing of the liquid outlet valve, and at the same time, the weight of the weighing inner box is detected by a gravity sensor, which not only improves production efficiency, but also greatly reduces the waste of pharmaceutical intermediates, helps to reduce production costs, and also ensures product consistency and stability. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is the overall front view of the utility model;

[0019] Figure 2 It is a structural schematic diagram of the upper reaction tank of the utility model;

[0020] Figure 3 It is a structural schematic diagram of the lower reaction tank of the utility model;

[0021] Figure 4 It is a structural schematic diagram of a weighing box of the utility model.

[0022] Among them, 1-adjusting platform, 10-lower mounting platform, 11-upper mounting platform, 12-hydraulic lifting element, 2-lower reaction tank, 20-first rotating motor, 21-liquid outlet valve, 22-plug ring, 3-upper reaction tank, 30-vertical stirring rod, 31-sealing ring, 32-annular groove, 33-second rotating motor, 4-weighing box, 40-placing rack, 41-fixed card box, 410-gravity sensor, 42-weighing inner box, 420-lifting handle. DETAILED DESCRIPTION

[0023] Example 1

[0024] like Figure 1 As shown, a compound efficient production equipment comprises an adjusting platform 1, a lower reaction tank 2 arranged on the adjusting platform 1, an upper reaction tank 3 arranged at the upper end of the adjusting platform 1 and opposite to the lower reaction tank 2, and a weighing box 4 arranged on the adjusting platform 1;

[0025] The lower reaction tank 2 is driven to rotate by the first rotating motor 20, the height of the adjusting platform 1 is adjustable, a liquid outlet valve 21 is provided on the side wall of the lower reaction tank 2, and a vertical stirring rod 30 is provided in the upper reaction tank 3; the weighing box 4 is connected to one side of the bottom end of the adjusting platform 1 through a placing rack 40, wherein the first rotating motor 20, the liquid outlet valve 21 and the vertical stirring rod 30 are all made of existing technologies, and the inner walls of the lower reaction tank 2 and the upper reaction tank 3 are sprayed with an anti-corrosion material layer, and the raw material used for the anti-corrosion material layer is polytetrafluoroethylene;

[0026] The adjusting platform 1 includes a lower mounting platform 10, an upper mounting platform 11 located at the upper end of the lower mounting platform 10, and a hydraulic lifting element 12 for connecting the upper mounting platform 11 and the lower mounting platform 10, wherein the hydraulic lifting element 12 adopts a hydraulic cylinder or a hydraulic lifter, which is a prior art, the upper reaction tank 3 is arranged at the lower end of the upper mounting platform 11, the lower reaction tank 2 is arranged at the upper end of the lower mounting platform 10, and the placement rack 40 is arranged at one side of the bottom end of the lower mounting platform 10, the upper reaction tank 3 and the lower end of the upper mounting platform 11, the lower reaction tank 2 and the upper end of the lower mounting platform 10, and the placement rack 40 and the bottom end of the lower mounting platform 10 are all in a movable connection mode, the purpose is to facilitate disassembly and replacement, the movable connection mode adopts a flange connection or a snap connection, when it is necessary to separate the lower reaction tank 2 and the upper reaction tank 3, the upper mounting platform 11 is lifted up by the extension of the hydraulic lifting element 12, so that the upper reaction tank 3 moves upward, and then the inner walls of the lower reaction tank 2 and the upper reaction tank 3 are cleaned or repaired, thereby increasing the convenience and work efficiency of cleaning and repair work;

[0027] like Figure 4 As shown, the weighing box 4 includes a fixed card box 41 arranged at the upper end of the placement frame 40, and a weighing inner box 42 movably connected to the inner wall of the fixed card box 41. A gravity sensor 410 is provided at the upper end of the fixed card box 41, and a lifting handle 420 is provided at the upper end of the weighing inner box 42. When the reaction is completed and the pharmaceutical intermediates in the lower reaction tank 2 and the upper reaction tank 3 need to be quantitatively discharged, the lower reaction tank 2 is driven to rotate by the first rotating motor 20. When the liquid outlet valve 21 is located at the upper end of the weighing inner box 42, the liquid outlet valve 21 is opened to discharge the pharmaceutical intermediates and drop them. To the weighing inner box 42, at the same time, the weight of the weighing inner box 42 is detected by the gravity sensor 410. When the discharged weight of the pharmaceutical intermediate and the weight of the weighing inner box 42 itself reach the set value, the liquid outlet valve 21 is closed, and then the weighing inner box 42 is taken out from the fixed card box 41 by pulling the handle 420. This not only improves the production efficiency, but also greatly reduces the waste of pharmaceutical intermediates, helps to reduce production costs, and also ensures the consistency and stability of the product. Among them, the gravity sensor 410 adopts the existing technology.

[0028] Example 2

[0029] The difference between this embodiment and embodiment 1 is that:

[0030] like Figure 2 , 3 As shown, a sealing ring 31 is provided at the bottom end of the upper reaction tank 3, and the inner diameter of the sealing ring 31 is 10 cm larger than the outer diameter of the lower reaction tank 2, and a plug-in ring 22 is provided at the upper end of the lower reaction tank 2, and an annular groove 32 matching the size of the plug-in ring 22 is provided at the bottom end of the upper reaction tank 3. When it is necessary to produce pharmaceutical intermediates, the lower reaction tank 2 and the upper reaction tank 3 are brought close to each other through the compression of the hydraulic lifting element 12 until the plug-in ring 22 at the upper end of the lower reaction tank 2 is inserted into the annular groove 32 at the bottom end of the upper reaction tank 3. At this time, the connecting joint between the lower reaction tank 2 and the upper reaction tank 3 is sealed by the sealing ring 31, which can ensure the normal production of pharmaceutical intermediates while avoiding leakage of reaction liquid or gas, thereby improving the overall working reliability of the reaction equipment.

[0031] Example 3

[0032] The difference between this embodiment and embodiment 2 is that:

[0033] like Figure 1 As shown, the vertical stirring rod 30 is driven to rotate by the second rotating motor 33, and the length of the vertical stirring rod 30 is equal to the sum of the heights of the lower reaction tank 2 and the upper reaction tank 3. When the raw materials of the pharmaceutical intermediates in the lower reaction tank 2 and the upper reaction tank 3 need to be stirred, the vertical stirring rod 30 can be driven by the second rotating motor 33 to rotate and stir, which can improve the reaction effect and the production efficiency of the pharmaceutical intermediates. The purpose of limiting the length of the vertical stirring rod 30 to be equal to the sum of the heights of the lower reaction tank 2 and the upper reaction tank 3 is to ensure that the vertical stirring rod 30 can completely cover the height of the entire reaction equipment, thereby achieving effective stirring, wherein the second rotating motor 33 adopts the existing technology.

[0034] A method for using a compound efficient production device of this embodiment includes the following steps:

[0035] S1. Place the raw materials for producing the pharmaceutical intermediate in the lower reaction tank 2, and make the lower reaction tank 2 and the upper reaction tank 3 approach each other through the compression of the hydraulic lifting element 12, until the plug ring 22 at the upper end of the lower reaction tank 2 is inserted into the annular groove 32 at the bottom end of the upper reaction tank 3, and at this time, the connection seam between the lower reaction tank 2 and the upper reaction tank 3 is sealed by the sealing ring 31;

[0036] S2, the second rotary motor 33 drives the vertical stirring rod 30 to rotate, stirring the raw materials of the pharmaceutical intermediates in the lower reaction tank 2 and the upper reaction tank 3, to ensure that the production of the pharmaceutical intermediates proceeds normally;

[0037] S3, when the reaction is finished, if the pharmaceutical intermediates in the lower reaction tank 2 and the upper reaction tank 3 need to be quantitatively discharged, the lower reaction tank 2 is driven to rotate by the first rotating motor 20, and when the liquid outlet valve 21 is located at the upper end of the weighing inner box 42, the liquid outlet valve 21 is opened to discharge the pharmaceutical intermediates and drop them into the weighing inner box 42. At the same time, the weight of the weighing inner box 42 is detected by the gravity sensor 410. When the discharged weight of the pharmaceutical intermediates and the weight of the weighing inner box 42 reach the set value, the liquid outlet valve 21 is closed;

[0038] S4. When the lower reaction tank 2 and the upper reaction tank 3 need to be separated, the upper mounting platform 11 is lifted up by the extension of the hydraulic lifting element 12 to move the upper reaction tank 3 upward.

Claims

1. A compound efficient production equipment, characterized in that: It comprises an adjusting platform (1), a lower reaction tank (2) arranged on the adjusting platform (1), an upper reaction tank (3) arranged at the upper end of the adjusting platform (1) and arranged opposite to the lower reaction tank (2), and a weighing box (4) arranged on the adjusting platform (1); The lower reaction tank (2) is driven to rotate by a first rotating motor (20), the height of the adjustment platform (1) is adjustable, a liquid outlet valve (21) is provided on the side wall of the lower reaction tank (2), and a vertical stirring rod (30) is provided in the upper reaction tank (3); the weighing box (4) is connected to one side of the bottom end of the adjustment platform (1) via a placement rack (40).

2. The compound efficient production equipment according to claim 1, characterized in that: The adjustment platform (1) comprises a lower mounting platform (10), an upper mounting platform (11) located at the upper end of the lower mounting platform (10), and a hydraulic lifting element (12) for connecting the upper mounting platform (11) and the lower mounting platform (10); the upper reaction tank (3) is arranged at the lower end of the upper mounting platform (11); the lower reaction tank (2) is arranged at the upper end of the lower mounting platform (10); and the placement rack (40) is arranged at one side of the bottom end of the lower mounting platform (10).

3. The compound efficient production equipment according to claim 1, characterized in that: A sealing ring (31) is provided at the bottom end of the upper reaction tank (3), the inner diameter of the sealing ring (31) is larger than the outer diameter of the lower reaction tank (2), and a plug-in ring (22) is provided at the upper end of the lower reaction tank (2), and an annular groove (32) matching the size of the plug-in ring (22) is provided at the bottom end of the upper reaction tank (3).

4. The compound efficient production equipment according to claim 1, characterized in that: The vertical stirring rod (30) is driven to rotate by a second rotating motor (33), and the length of the vertical stirring rod (30) is equal to the sum of the heights of the lower reaction tank (2) and the upper reaction tank (3).

5. The compound efficient production equipment according to claim 1, characterized in that: The weighing box (4) comprises a fixed card-jointed box (41) arranged at the upper end of the placement rack (40), and a weighing inner box (42) movably connected to the inner wall of the fixed card-jointed box (41); a gravity sensor (410) is arranged at the upper end of the fixed card-jointed box (41), and a lifting handle (420) is arranged at the upper end of the weighing inner box (42).

Images