Biological membrane hold-down device
By designing a biofilm pressing device including a first anti-adhesive plate, a second anti-adhesive plate and a pressing block, the problem of uneven biofilm traces in the prior art is solved, and a more uniform texture depth and correct fixation of the biofilm are achieved.
Patent Information
- Application Number
- CN202421824219.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-30
- Publication Date
- 2025-05-13
- Estimated Expiration
- 2034-07-30
AI Technical Summary
The existing biofilm pressing method leads to uneven stress and uneven textures formed, which affects the use effect.
A biofilm pressing device is designed to clamp the biofilm through the first anti-adhesive plate and the second anti-adhesive plate, and the biofilm is pressed to form a pattern using the weight of the pressing block itself. Combined with the coordination of the positioning rod and the positioning hole, it ensures the correct assembly and fixation of the pressing block and the base.
It achieves a more uniform depth of the biofilm pattern, ensures easy resolution of the front and back sides of the biofilm, and avoids the curling and adhesion of the biofilm.
Smart Images
Figure CN222858745U_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of biofilm preparation, and in particular to a biofilm holding device. Background Art
[0002] Biofilms are derived from biological tissues, for example, the small intestinal submucosa is derived from the small intestine. When the small intestinal submucosa is used to make medical devices, it is usually necessary to first decellularize and then dry. Since the small intestinal submucosa is very thin and generally curled, for later use, the small intestinal submucosa needs to be pressed flat before drying. The small intestinal submucosa can be used to make oral biofilms. One surface of the oral biofilm has texture, which is used for periodontal and alveolar soft and hard tissue repair treatment. The texture of the oral biofilm is usually pressed by a pressing plate. The inventor of the present application tried to use a nut and a screw to apply pressure to the pressing plate, so that the pressing plate forms textures on the surface of the biofilm. However, the inventor of the present application found that this method would cause uneven force and uneven texture, which would affect the use effect. Utility Model Content
[0003] The present application provides a biofilm pressing device, which can press and hold the biofilm for drying, and the texture formed by the biofilm is more uniform.
[0004] This application is implemented as follows:
[0005] The present application provides a biofilm holding device, which comprises:
[0006] A first pressing module, the first pressing module comprising a pressing base and a first anti-sticking plate, the pressing base is provided with a first groove, and the first anti-sticking plate is used to be arranged in the first groove; and
[0007] A second pressing module, the second pressing module comprising a pressing block and a second anti-sticking plate, the pressing block is provided with a second groove, and the second anti-sticking plate is used to be arranged in the second groove;
[0008] Either one of the pressing base and the pressing block has a positioning rod, and the other has a positioning hole matching the positioning rod; the first anti-sticking plate or the second anti-sticking plate is provided with convex patterns; the biofilm is used to be pressed between the first anti-sticking plate and the second anti-sticking plate, and when the biofilm is pressed between the first anti-sticking plate and the second anti-sticking plate, the positioning rod is inserted into the positioning hole, and the pressing block presses the pressing base and can press the biofilm to form patterns by gravity.
[0009] In a possible implementation, the density of the holding block is greater than or equal to the density of stainless steel.
[0010] In a possible implementation manner, the holding block is a stainless steel block, a tungsten carbide block, a tungsten alloy block, a metal tungsten block, a metal iridium block or a gold block.
[0011] In a possible embodiment, the thickness of the first anti-sticking plate is smaller than the depth of the first groove, the top surface of the first anti-sticking plate and the side surface of the first groove form a recessed portion, the thickness of the second anti-sticking plate is greater than the depth of the second groove, and the second anti-sticking plate can be embedded in the recessed portion and clamp the biofilm together with the first anti-sticking plate.
[0012] In a possible implementation manner, when the second anti-sticking plate is embedded in the recessed portion, the distance between the side surface of the second anti-sticking plate and the side surface of the first groove is 0.3-2 mm.
[0013] In a possible implementation manner, an end of the holding block that is away from the first groove is connected to a lifting member, and the lifting member is used to assist in lifting.
[0014] In a possible implementation manner, the lifting member has a gripping portion, which is annular and forms a gripping channel.
[0015] In a possible embodiment, the first anti-sticking plate and / or the second anti-sticking plate are both provided with a first through hole along the thickness direction, and the pressing base and / or the pressing block are both provided with a second through hole along the thickness direction, and the second through holes and the first through holes are arranged one-to-one and connected to each other.
[0016] In a possible implementation manner, the diameter of the second through hole is greater than or equal to the diameter of the first through hole.
[0017] In a possible implementation, the convex pattern includes a plurality of anti-sticking portions arranged side by side, and the first through holes are formed between adjacent anti-sticking plates.
[0018] In a possible embodiment, both the first anti-sticking plate and the second anti-sticking plate are polytetrafluoroethylene plates.
[0019] This application has at least the following beneficial effects:
[0020] The biofilm pressing device of the present application clamps the biofilm by the first anti-adhesion plate and the second anti-adhesion plate, and the pressing block presses the pressing base. Through the weight of the pressing block itself, one side of the biofilm is pressed to form lines, so as to facilitate the separation of the front and back sides of the biofilm. Since the lines of the biofilm are formed by the weight of the pressing block itself, the force is more uniform, and thus the depth of the lines is more uniform. In addition, through the cooperation of the positioning rod and the positioning hole, the pressing block and the pressing base are not easily displaced from each other during assembly, and the biofilm is not easy to curl. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present application and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.
[0022] Figure 1 A schematic diagram of a biofilm holding device according to an embodiment of the present application;
[0023] Figure 2 for Figure 1 An assembly structure diagram of a first pressing module and a second pressing module of a biofilm pressing device;
[0024] Figure 3 A cross-sectional view of a second anti-sticking plate according to an embodiment of the present application;
[0025] Figure 4 A schematic diagram of another biofilm holding device according to an embodiment of the present application;
[0026] Figure 5 Schematic diagram of a biofilm holding device according to an embodiment of the present application.
[0027] Icons: 10-biofilm pressing device; 11-first pressing module; 111-pressing base; 1111-first groove; 112-first anti-sticking plate; 113-recessed portion; 12-second pressing module; 121-pressing block; 1211-second groove; 122-second anti-sticking plate; 13-positioning rod; 14-positioning hole; 15-lifting piece; 151-holding portion; 1511-holding channel; 161-first through hole; 162-second through hole; 17-embossed pattern; 171-anti-sticking portion. DETAILED DESCRIPTION
[0028] In order to make the purpose, technical solution and advantages of the embodiments of the present application clearer, the technical solution in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are part of the embodiments of the present application, rather than all the embodiments. The components of the embodiments of the present application described and shown in the drawings here can be arranged and designed in various different configurations.
[0029] Therefore, the following detailed description of the embodiments of the present application provided in the accompanying drawings is not intended to limit the scope of the present application for which protection is sought, but merely represents selected embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in the field without creative work are within the scope of protection of the present application.
[0030] In the description of the present application, it should be noted that the terms "first", "second", etc. are only used to distinguish the description and cannot be understood as indicating or implying relative importance.
[0031] In the description of this application, it should also be noted that, unless otherwise clearly specified and limited, the terms "disposed" and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a direct connection, or an indirect connection through an intermediate medium, or it can be the internal communication of two elements. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances. Example
[0032] This embodiment provides a biofilm holding device 10, please refer to Figure 1 and Figure 2 , which includes a first pressing module 11 and a second pressing module 12. The first pressing module 11 includes a pressing base 111 and a first anti-sticking plate 112. The pressing base 111 is provided with a first groove 1111, and the first anti-sticking plate 112 is used to be arranged in the first groove 1111. The first anti-sticking plate 112 can be fixed in the first groove 1111, or the first anti-sticking plate 112 and the pressing base 111 can be separately arranged. When it is needed, the first anti-sticking plate 112 is assembled in the first groove 1111 of the pressing base 111, and then used in conjunction with the second pressing module 12.
[0033] The second pressing module 12 includes a pressing block 121 and a second anti-sticking plate 122. The pressing block has a second groove 1211. The second anti-sticking plate 122 is used to be arranged in the second groove 1211. The second anti-sticking plate 122 can be fixed in the second groove 1211, or the second anti-sticking plate 122 and the pressing block 121 can be separately arranged. When it is needed, the second anti-sticking plate 122 is assembled in the second groove 1211 of the pressing block 121, and then used in conjunction with the first pressing module 11.
[0034] Either one of the pressing base 111 and the pressing block 121 has a positioning rod 13, and the other has a positioning hole 14 matching the positioning rod 13. That is to say, the pressing base 111 may be provided with the positioning rod 13, and the pressing block 121 may be provided with the positioning hole 14, or the pressing block 121 may be provided with the positioning rod 13, and the pressing base 111 may be provided with the positioning hole 14. Wherein, both the pressing base 111 and the pressing block 121 have a positioning portion, the positioning portion of the pressing base 111 is arranged along the first groove 1111, and the positioning portion of the pressing block 121 is arranged along the second groove 1211, and the positioning rod 13 and the positioning hole 14 are arranged in the positioning portion. Exemplarily, a plurality of the positioning rods 13 and the positioning holes 14 are provided, and are evenly spaced along the positioning portion and surround the first groove 1111 and the second groove 1211. Since the plurality of positioning rods 13 and the plurality of positioning holes 14 cooperate with each other, the first pressing module 11 and the second pressing module 12 are less likely to shift after being assembled.
[0035] The first anti-adhesion plate 112 or the first anti-adhesion plate 112 is provided with a convex pattern 17 (refer to Figure 3 ), the biofilm is used to be pressed between the first anti-sticking plate 112 and the second anti-sticking plate 122. When the biofilm is pressed between the first anti-sticking plate 112 and the second anti-sticking plate 122, the positioning rod 13 is inserted into the positioning hole 14, and the pressing block 121 presses the pressing base 111 and can rely on gravity to press the biofilm to form textures.
[0036] The biofilm pressing device 10 of the present application clamps the biofilm by the first anti-adhesion plate 112 and the second anti-adhesion plate 122, and the pressing block 121 presses the pressing base 111. Through the weight of the pressing block 121 itself, one side of the biofilm is pressed to form lines, thereby facilitating the separation of the front and back sides of the biofilm. Since the lines of the biofilm are formed by the weight of the pressing block 121 itself, the force is more uniform, and thus the depth of the lines is more uniform. In addition, through the positioning rod 13 and the positioning hole 14, the pressing block 121 and the pressing base are not easily displaced from each other during assembly, and the biofilm is not easily curled.
[0037] Furthermore, since the biofilm is directly sandwiched between the first anti-sticking plate 112 and the second anti-sticking plate 122, the biofilm will not adhere to the first anti-sticking plate 112 and the second anti-sticking plate 122, so it is convenient to remove the treated biofilm from between the first anti-sticking plate 112 and the second anti-sticking plate 122. Optionally, the first anti-sticking plate 112 and the second anti-sticking plate 122 are both polytetrafluoroethylene plates. The polytetrafluoroethylene plate not only has an anti-sticking effect, but also is high temperature resistant and can be used for high temperature pressing of the biofilm.
[0038] The density of the holding block 121 is greater than or equal to the density of stainless steel, and the density of stainless steel is between 7.65 and 8.0 g / cm 3This means that the density of the pressing block 121 is greater than or equal to 7.65 g / cm 3 , the density of the holding block 121 is relatively large, so the volume is smaller under the condition of consistent weight, and it is more convenient to use. Optionally, the holding block 121 is a stainless steel block, a tungsten carbide block, a tungsten alloy block, a metal tungsten block, a metal iridium block or a gold block. The above holding blocks 121 have a relatively large density and are resistant to high temperature and corrosion, and can be used for high-temperature pressing of biofilms. It should be noted that the depth of the texture is determined by the weight of the holding block 121. When deeper textures are required, a heavier holding block 121 is used. When shallower textures are required, a lighter holding block 121 can be used. It can be understood that light and heavy are only relative, and the user can choose the weight of the holding block 121 as needed.
[0039] In addition, in order to more conveniently lift the pressing block 121 and assemble it with the second anti-adhesion plate 122 and the first pressing module 11, illustratively, the end of the pressing block 121 away from the first groove 1111 is connected with a lifting member 15 (refer to Figure 5 ), the lifting member 15 is used to assist in lifting, so as to facilitate lifting the pressing block 121. Exemplarily, the lifting member 15 has a gripping portion 151, which is annular and forms a gripping channel 1511. By passing a hand through the gripping channel 1511 of the gripping portion 151 and gripping the gripping portion 151, it is more convenient to lift the pressing block 121 with force.
[0040] Furthermore, during the drying process of the biofilm, water vapor will escape. In order to facilitate the discharge of water vapor, the first anti-adhesion plate 112 and / or the second anti-adhesion plate 122 are provided with a first through hole 161 along the thickness direction, and the pressure holding base 111 and / or the pressure holding block 121 are provided with a second through hole 162 along the thickness direction, and the second through hole 162 and the first through hole 161 are arranged in a one-to-one correspondence and are interconnected. For example, the first anti-adhesion plate 112 is provided with a first through hole 161, and the pressure holding base 111 is provided with a second through hole 162, and the first through hole 161 and the second through hole 162 are arranged in a one-to-one correspondence and are interconnected. For another example, the second anti-adhesion plate 122 is provided with a first through hole 161, and the pressure holding block 121 is provided with a second through hole 162, and the first through hole 161 and the second through hole 162 are arranged in a one-to-one correspondence and are interconnected. The water vapor generated by the biofilm during freeze drying or heat treatment can be discharged sequentially through the first through hole 161 and the second through hole 162. Optionally, the aperture of the second through hole 162 is greater than or equal to the aperture of the first through hole 161, so as to facilitate the discharge of water vapor.
[0041] Exemplarily, the convex pattern 17 includes anti-adhesion portions 171 arranged side by side, and the first through holes 161 mentioned above are formed between adjacent anti-adhesion portions 171 (see Figure 3). Under the action of the weight of the pressing block 121, the anti-adhesion portion 171 acts on the surface of the biofilm to form lines, and the first through hole 161 can facilitate the discharge of water vapor.
[0042] For further information, please refer to Figure 1 and Figure 2 The thickness of the first anti-sticking plate 112 is less than the depth of the first groove 1111, the top surface of the first anti-sticking plate 112 and the side surface of the first groove 1111 form a recessed portion 113, the thickness of the second anti-sticking plate 122 is greater than the depth of the second groove 1211, and the second anti-sticking plate 122 can be embedded in the recessed portion 113 and clamp the biofilm together with the first anti-sticking plate 112.
[0043] During use, the biofilm is placed on the top surface of the first anti-adhesion plate 112. Since the top surface of the first anti-adhesion plate 112 and the side surface of the first groove 1111 are enclosed to form a recessed portion 113, the side surface of the first groove 1111 can restrict the biofilm, reducing the probability of the biofilm shifting on the top surface of the first anti-adhesion plate 112. In addition, the second anti-adhesion plate 122 can be embedded in the recessed portion 113, further reducing the probability of relative displacement between the second pressing module 12 and the first pressing module 11.
[0044] Exemplarily, when the second anti-adhesion plate 122 is embedded in the recessed portion 113, the distance between the side of the second anti-adhesion plate 122 and the side of the first groove 1111 is 0.3-2 mm. The distance between the side of the second anti-adhesion plate 122 and the side of the first groove 1111 is 0.3-2 mm, which not only facilitates the embedding of the second anti-adhesion plate 122 in the recessed portion 113, but also the second anti-adhesion plate 122 has a small movable space in the recessed portion 113, and is not easy to cause relative displacement.
[0045] It is understood that in other embodiments, the thickness of the first anti-adhesion plate 112 may be consistent with the depth of the first groove 1111, and the thickness of the second anti-adhesion plate 122 may be consistent with the depth of the second groove 1211 (see Figure 4 ). When the first anti-adhesion plate 112 and the second anti-adhesion plate 122 clamp the biofilm, the holding block 121 and the holding base 111 contact and resist each other. In other embodiments, it can also be configured that the thickness of the first anti-adhesion plate 112 is greater than the depth of the first groove 1111, and the thickness of the second anti-adhesion plate 122 is greater than the depth of the second groove 1211. When the first anti-adhesion plate 112 and the second anti-adhesion plate 122 clamp the biofilm, there is a certain distance between the holding block 121 and the holding base 111.
[0046] In summary, the biofilm pressing device 10 of the present application clamps the biofilm by the first anti-adhesion plate 112 and the second anti-adhesion plate 122, and the pressing block 121 presses the pressing base 111, and the weight of the pressing block 121 itself presses one side of the biofilm to form lines, thereby facilitating the separation of the front and back sides of the biofilm. Since the lines of the biofilm are formed by the weight of the pressing block 121 itself, the force is more uniform, and thus the depth of the lines is more uniform. In addition, the positioning rod 13 cooperates with the positioning hole 14, so that the pressing block 121 and the pressing base are not easily displaced from each other during assembly, and the biofilm is not easily curled.
[0047] The above are only preferred embodiments of the present application and are not intended to limit the present application. For those skilled in the art, the present application may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present application shall be included in the protection scope of the present application.
Claims
1. A biofilm holding device, characterized in that: include: A first pressing module, the first pressing module comprising a pressing base and a first anti-sticking plate, the pressing base is provided with a first groove, and the first anti-sticking plate is used to be arranged in the first groove; and A second pressing module, the second pressing module comprising a pressing block and a second anti-sticking plate, the pressing block is provided with a second groove, and the second anti-sticking plate is used to be arranged in the second groove; Either one of the pressing base and the pressing block has a positioning rod, and the other has a positioning hole matching the positioning rod; the first anti-sticking plate or the second anti-sticking plate is provided with convex patterns; the biofilm is used to be pressed between the first anti-sticking plate and the second anti-sticking plate, and when the biofilm is pressed between the first anti-sticking plate and the second anti-sticking plate, the positioning rod is inserted into the positioning hole, and the pressing block presses the pressing base and can press the biofilm to form patterns by gravity.
2. The biofilm holding device according to claim 1, characterized in that: The density of the holding block is greater than or equal to the density of stainless steel.
3. The biofilm holding device according to claim 1, characterized in that: The holding block is a stainless steel block, a tungsten carbide block, a tungsten alloy block, a metal tungsten block, a metal iridium block or a gold block.
4. The biofilm holding device according to any one of claims 1 to 3, characterized in that: The thickness of the first anti-sticking plate is smaller than the depth of the first groove, the top surface of the first anti-sticking plate and the side surface of the first groove form a recessed portion, the thickness of the second anti-sticking plate is greater than the depth of the second groove, the second anti-sticking plate can be embedded in the recessed portion and clamp the biofilm together with the first anti-sticking plate.
5. The biofilm holding device according to claim 4, characterized in that: When the second anti-sticking plate is embedded in the recessed portion, the distance between the side surface of the second anti-sticking plate and the side surface of the first groove is 0.3-2 mm.
6. The biofilm holding device according to any one of claims 1 to 3, characterized in that: One end of the pressing block away from the first groove is connected with a lifting member, and the lifting member is used for assisting lifting.
7. The biofilm holding device according to claim 6, characterized in that: The lifting member has a gripping portion, which is annular and forms a gripping channel.
8. The biofilm holding device according to any one of claims 1 to 3, characterized in that: The first anti-sticking plate and / or the second anti-sticking plate are both provided with a first through hole along the thickness direction, and the holding base and / or the holding block are both provided with a second through hole along the thickness direction, and the second through hole and the first through hole are arranged one by one and connected to each other.
9. The biofilm holding device according to claim 8, characterized in that: The diameter of the second through hole is greater than or equal to the diameter of the first through hole.
10. The biofilm holding device according to claim 8, characterized in that: The convex pattern includes a plurality of anti-sticking portions arranged side by side, and the first through hole is formed between adjacent anti-sticking plates.