Diluent bin with movable bin position and chemical immunoluminescence instrument thereof

Abstract

The diluent bin with the movable bin positions comprises a diluent bin body provided with a plurality of containing cavities, the diluent bin body is movably arranged on a conveying track, the first end of the conveying track is a liquid bin working position, and the second end of the conveying track is a liquid bin replacing position; a plurality of liquid bottles are respectively placed in the plurality of accommodating cavities; and the diluent bin body carries a plurality of liquid bottles to reciprocate between the liquid bin working position and the liquid bin replacing position along the conveying track under the action of a driving mechanism. The diluent bin with the movable bin position can move on the front portion and the rear portion of an instrument, consumables in the diluent bin can be conveniently replaced, a special cleaning agent can be placed in the diluent bin, an extra special cleaning agent device does not need to be arranged, the production cost of the instrument is reduced, the detection process is optimized, and the control cost of the whole detection process is reduced.

Description

Technical Field

[0001] The present application relates to the technical field of immunoassay equipment, and in particular to a diluent bin with a movable position and a chemiimmunoluminometer thereof. Background Art

[0002] In the chemiimmunoluminometer, the diluent tank plays an important role. It is usually connected to the instrument's automation system and can automatically add the appropriate amount of diluent to a specific sample according to a preset program, thereby achieving an efficient and standardized test process. The liquid in the diluent tank is used to dilute the original sample so that the concentration of the substance to be tested in the sample reaches the range that the instrument can accurately detect. This is especially important for high-concentration samples to avoid saturation or exceeding the detection limit of the instrument. Through dilution, the impact of interfering substances that may exist in the sample on the test results can be effectively reduced, and the specificity and sensitivity of the determination can be improved. The diluent may contain some buffer components or other chemicals, which can help adjust the pH value or ionic strength of the sample, making the sample more suitable for subsequent reaction conditions. The use of standardized diluents can ensure the repeatability and comparability of the experiment, because each dilution is strictly carried out under the same conditions, reducing the error caused by operating variables.

[0003] However, in order to facilitate the absorption of diluents and to reasonably arrange the internal structures of the chemiimmunoluminometer, the workstation for absorbing diluents is located at the back of the instrument, while the tester is located at the front of the instrument, far away from the diluent tank. When the liquid bottle in the liquid tank needs to be replaced, it often takes a lot of time and it is inconvenient to replace consumables.

[0004] Moreover, in the existing chemiimmunoluminometer, a special cleaning agent is sometimes needed to clean the sample needle before it can be used again. However, the frequency of use is not high, and the separate loading device and cleaning device of the special cleaning agent take up more space and increase the production cost.

[0005] Therefore, it is a technical problem to be solved urgently to design a diluent tank that is convenient for replacing consumables and can be used for multiple functions, has a compact and reasonable structure, and reduces production costs. Utility Model Content

[0006] In response to the technical problems existing in the prior art, the present application proposes a dilution liquid tank with a movable position and a chemical immunoluminescence instrument thereof; wherein the dilution liquid tank with a movable position can be moved at the front and rear of the instrument, so as to facilitate the replacement of consumables in the liquid tank, and cleaning agent can be placed in the liquid tank without the need for an additional cleaning agent device. The structure is compact and reasonable, and the production cost of the instrument is reduced, and the detection process is optimized, thereby reducing the control cost of the entire detection process.

[0007] The present application proposes a diluent bin with movable positions, comprising a diluent bin body provided with a plurality of accommodating chambers, wherein the diluent bin body is movably arranged on a conveying track, wherein a first end of the conveying track is a liquid bin working position, and a second end of the conveying track is a liquid bin replacement position, and a plurality of liquid bottles are respectively placed in the plurality of the accommodating chambers; the diluent bin body carries the plurality of liquid bottles and reciprocates between the liquid bin working position and the liquid bin replacement position along the conveying track under the action of a driving mechanism.

[0008] Optionally, according to an embodiment of the present application, the liquid bottle can be used to hold different diluents and cleaning agents, and the total amount of solution loaded in the liquid bottle is a fixed value, that is, a preset consumption, and the amount of solution in the corresponding liquid bottle absorbed each time is also a fixed value; the control unit calculates the consumption times of each liquid bottle respectively, and when the corresponding preset consumption is reached, the control unit displays that there is no liquid in the bottle and transmits a driving signal to the driving mechanism to drive the diluent tank to move from the liquid tank working position to the liquid tank replacement position.

[0009] Optionally, according to an embodiment of the present application, a sensor is provided on the side of each of the accommodating chambers to detect the state of the liquid bottle in the accommodating chamber. When the sensor detects that the corresponding accommodating chamber is empty, an empty signal is generated; when the sensor detects that the corresponding accommodating chamber is loaded with the liquid bottle, a new liquid bottle loading signal is generated.

[0010] Optionally, according to an embodiment of the present application, each of the accommodating chambers is provided with a corresponding status indicator light. When the control unit displays that there is no liquid in the bottle, the status indicator light turns on a first color. When the control unit receives an empty signal, the status indicator light turns on a second color. When the control center receives a signal for loading a new liquid bottle, the status indicator light turns on a third color.

[0011] Optionally, according to an embodiment of the present application, the liquid bottle is provided with a safety line, and when the solution in the liquid bottle is lower than the safety line, the status indicator light lights up the first color accordingly.

[0012] Optionally, according to an embodiment of the present application, a plurality of engaging members are further provided at the bottom of each of the accommodating chambers, and a plurality of the engaging members extend claws with a certain length toward the interior of the accommodating chamber; a plurality of ridges are provided on the side edge of the liquid bottle close to the bottom of the accommodating chamber, and a height of the claws from the bottom of the accommodating chamber is adapted to a height of the ridge from the bottom of the accommodating chamber; and a plurality of the claws are engaged on the plurality of ridges.

[0013] Optionally, according to an embodiment of the present application, a mounting seat is further included, the conveying track is laid on the mounting seat, support plates of a certain length are respectively extended downward from both ends of the mounting seat, and a fixing plate is provided at one end of the support plate in contact with the fixed plane and is in surface contact with the fixed plane.

[0014] Optionally, according to an embodiment of the present application, an electronic tag reader is further provided on the diluent tank body for reading a barcode pasted on the liquid bottle and recording information on the type, batch number and capacity of the liquid.

[0015] The present application also proposes a chemical immunoluminescence instrument, which at least includes a sample library and a reagent chamber, and is characterized in that it also includes a dilution liquid chamber with a movable position as described in any of the above items, wherein the dilution liquid chamber is used to hold a diluted reaction solution and reciprocates between a liquid chamber working position and a liquid chamber replacement position.

[0016] Optionally, according to an embodiment of the present application, the diluent tank is also used to hold a cleaning agent for cleaning the pipette needle.

[0017] The dilution liquid tank with a movable position of the present application can be moved at the front and rear of the instrument, which is convenient for replacing consumables in the liquid tank, and cleaning agent can be placed in the liquid tank without the need for additional cleaning agent device, thereby reducing the production cost of the instrument, optimizing the detection process, and reducing the control cost of the entire detection process. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Below, the preferred embodiments of the present application will be further described in detail with reference to the accompanying drawings, wherein:

[0019] Figure 1 It is a schematic diagram of the overall structure of a diluent bin with a movable bin position according to an embodiment of the present application;

[0020] Figure 2 is a perspective view of a diluent tank body according to an embodiment of the present application.

[0021] Reference numerals: diluent tank body 10 ; liquid bottle 11 ; sensor 12 ; engaging member 15 ; status indicator light 17 ; conveying track 20 ; liquid tank working position 21 ; liquid tank replacement position 22 ; mounting seat 25 . DETAILED DESCRIPTION

[0022] In order to make the purpose, technical solution and advantages of the embodiments of the present application clearer, the technical solution in the embodiments of the present application will be clearly and completely described below in conjunction with the drawings in the embodiments of the present application. Obviously, the described embodiments are part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0023] In the following detailed description, reference may be made to the various specification drawings that are part of the present application and are used to illustrate specific embodiments of the present application. In the accompanying drawings, similar reference numerals describe substantially similar components in different figures. The various specific embodiments of the present application are described below in sufficient detail so that a person of ordinary skill in the art with relevant knowledge and skills in the art can implement the technical solutions of the present application. It should be understood that other embodiments may also be used or structural, logical or electrical changes may be made to the embodiments of the present application.

[0024] like Figure 1 As shown, the present application proposes a diluent bin with movable positions, including a diluent bin body 10 with multiple accommodating chambers, the diluent bin body 10 is movably connected to a conveying track 20, the first end of the conveying track 20 is a liquid bin working position 21, the second end of the conveying track is a liquid bin replacement position 22, and multiple liquid bottles 11 are placed in the multiple accommodating chambers; the diluent bin body 10 carries multiple liquid bottles 11 and reciprocates between the liquid bin working position 21 and the liquid bin replacement position 22 along the conveying track 20 under the action of a driving mechanism (not shown in the figure). It should be noted that for the convenience of explanation, Figure 1 The dilution liquid bin body is arranged at both the liquid bin working position and the liquid bin replacement position. However, in actual application, the dilution liquid bin body reciprocates between the liquid bin working position and the liquid bin replacement position during operation, and does not exist at both positions at the same time.

[0025] Figure 1 In the embodiment, the diluent tank body 10 loaded with a plurality of liquid bottles 11 is located at the liquid tank working position 21 at the rear end of the instrument, and Figure 1 The diluent tank body 10 located at the tank replacement position 22 is schematically drawn. In order to facilitate viewing of the engaging member 15 inside the accommodating chamber, the accommodating chamber is in an empty state without the liquid bottle 11 placed therein.

[0026] like Figure 1 As shown in the empty dilution liquid bin body 10 of the middle liquid bin working position 21, in some embodiments, a plurality of engaging members 15 are further provided at the bottom of each of the accommodating chambers, and a plurality of the engaging members 15 extend claws with a certain length toward the interior of the accommodating chamber (not shown in the figure); a plurality of ridges (not shown in the figure) are provided on the side edge of the liquid bottle 11 close to the bottom of the accommodating chamber, and the height of the claws from the bottom of the accommodating chamber is adapted to the height of the ridges from the bottom of the accommodating chamber; a plurality of the claws are engaged on the plurality of ridges to give the liquid bottle 11 a certain downward pulling force to stabilize it inside the accommodating chamber.

[0027] The diluent tank with a movable position of the present application can be moved between the front and rear of the instrument, which is convenient for replacing consumables in the tank. When the consumables need to be replaced, the driving mechanism drives the diluent tank body to move from the rear end of the instrument to the front end of the instrument for convenient operation. After the staff has replaced the consumables, the driving mechanism drives the diluent tank body to move from the front end of the instrument to the working position at the rear end of the instrument.

[0028] Continue as Figure 1 As shown, the plurality of liquid bottles 11 include liquid bottles 11 containing different diluents and liquid bottles 11 containing cleaning agents. The total amount of solution loaded into the different types of liquid bottles 11 is fixed, and the solution in the corresponding liquid bottle 11 is quantitatively drawn each time. In some embodiments, the bottle bodies of the liquid bottle containing the cleaning agent and the liquid bottle containing the diluent have a fool-proof function, so that the two will not be misplaced. Figure 1-Figure 2 As shown, the three lower ones are liquid bottles 11 filled with special cleaning agents, and the shapes of their bottle bodies are different from the top liquid bottle filled with special cleaning agents, and the shapes of the corresponding accommodating chambers are also different.

[0029] Before turning on the instrument, the staff can pre-set the total amount of solution corresponding to different types of liquid bottles in the control unit. The aspiration needle that absorbs the solution in the liquid bottle quantitatively absorbs the solution each time, and the control unit can calculate the consumption of each of the liquid bottles according to the number of times the aspiration needle absorbs the solution, and convert the remaining amount of solution in the bottle. When the consumption of each of the liquid bottles reaches the corresponding preset consumption, the control unit displays that there is no liquid in the bottle and transmits a driving signal to the driving mechanism to drive the dilution liquid tank to move from the liquid tank working position to the liquid tank replacement position.

[0030] By pre-setting the preset consumption values ​​of various types of diluents or special cleaning agents in the control unit, when the corresponding actual consumption exceeds the preset value, the driving mechanism can automatically drive the diluent tank to move to the front end of the instrument to remind the staff to replace the consumables, thereby avoiding the situation where the amount of solution absorbed is lower than the usage amount due to untimely replacement of consumables, resulting in inaccurate test results or incomplete cleaning of the aspiration needle.

[0031] Continue to combine Figure 2 As shown, a sensor 12 is provided on the side of each of the accommodating chambers. When the diluent tank body 10 lacking liquid in the bottle is transferred to the tank replacement position 22 to wait for the staff to replace the lacking liquid bottle with a new one, after the staff takes out the liquid bottle, the sensor 12 generates an empty signal and sends it to the control unit, which serves to remind this accommodating chamber that there is no liquid bottle 11 loaded. When the staff puts the new liquid bottle 11 into the accommodating chamber, the sensor 12 generates a new liquid bottle loading signal corresponding to the accommodating chamber after the liquid bottle 11 is loaded and sends it to the control unit for recording.

[0032] In some embodiments, each of the accommodating chambers is provided with a status indicator light 17. When the control unit indicates that the bottle is short of liquid, the status indicator light 17 lights up in the first color. When the control unit receives an empty signal, the status indicator light 17 lights up in the second color. When the control unit receives a signal to load a new liquid bottle, the status indicator light 17 lights up in the third color. The three-color light can clearly display whether there is a liquid bottle loaded in the accommodating chamber and whether the liquid bottle is short of liquid. The action to be taken can be intuitively and clearly known without confirmation by the control unit. In some embodiments, the liquid bottle 11 is provided with a safety line. When the solution in the liquid bottle is lower than the safety line, the status indicator light 17 lights up in the first color. When the solution line in the liquid bottle 11 reaches the safety line position, if the consumed liquid volume is less than the expected consumption, an early warning can be issued for the lack of liquid in the bottle, which can give the staff more reaction time to prepare liquid and prepare for liquid replacement, effectively improving the smoothness of equipment operation.

[0033] like Figure 1 As shown, in some embodiments, a mounting seat 25 is further included, and the conveying track 20 is laid on the mounting seat 25. Support plates (not shown in the figure) with a certain length extend downward from both ends of the mounting seat 25, and a fixing plate (not shown in the figure) in contact with the fixed plane is provided at one end of the support plate. The mounting seat 25 raises the conveying track 20 to a certain height so that it is at a suitable height. The height of the track can be adjusted to the best position suitable for the actual working environment by adjusting the length of the support plate.

[0034] In some embodiments, the diluent tank body 10 is also provided with an electronic tag reader (not shown in the figure) for reading the barcode on the liquid bottle that records the type, batch number and volume information of the solution. The advantage of this design is that if there is a wrong installation, the electronic tag reader will give an error feedback, so that it can be ensured that the installed liquid bottle 11 is in the correct accommodation chamber.

[0035] The present application also proposes a chemiimmunoluminometer, which comprises at least a sample library and a reagent chamber, and also comprises a diluent chamber with a movable position as described in any of the above items, wherein the diluent chamber is used to dilute the reaction solution or clean the pipette needle.

[0036] Placing the liquid bottle containing the cleaning agent into the diluent tank can greatly reduce the production cost and operation cost of the chemical immunoluminescence instrument. In the prior art, in order to clean the liquid aspiration needle, a cleaning device that can spray cleaning agent is separately provided, which is not only not conducive to the overall utilization of the operating space, but also increases the production cost.

[0037] The dilution liquid tank with a movable position of the present application can be moved at the front and rear of the instrument, which is convenient for replacing consumables in the liquid tank, and special cleaning agents can be placed in the liquid tank without the need for additional special cleaning agent devices, thereby reducing the production cost of the instrument, optimizing the detection process, and reducing the control cost of the entire detection process.

[0038] The above embodiments are only used to illustrate the present application, and are not intended to limit the present application. Ordinary technicians in the relevant technical field may make various changes and modifications without departing from the scope of the present application. Therefore, all equivalent technical solutions should also fall within the scope disclosed in the present application.

Claims

1. A diluent tank with a movable position, characterized in that: The invention comprises a diluent bin body provided with a plurality of accommodating chambers, wherein the diluent bin body is movably arranged on a conveying track, wherein a first end of the conveying track is a liquid bin working position, and a second end of the conveying track is a liquid bin replacement position, and a plurality of liquid bottles are respectively placed in the plurality of accommodating chambers; and the diluent bin body carries the plurality of liquid bottles and reciprocates between the liquid bin working position and the liquid bin replacement position along the conveying track under the action of a driving mechanism.

2. The diluent tank with movable positions according to claim 1, characterized in that: The liquid bottle can be used to hold different diluents and cleaning agents. The total amount of solution loaded in the liquid bottle is a fixed value, that is, a preset consumption amount, and the amount of solution in the liquid bottle corresponding to each aspiration is also a fixed value; The control unit calculates the consumption times of each of the liquid bottles respectively. When the corresponding preset consumption is reached, the control unit displays that there is no liquid in the bottle and transmits a driving signal to the driving mechanism to drive the diluent tank to move from the liquid tank working position to the liquid tank replacement position.

3. The diluent tank with movable positions according to claim 1, characterized in that: A sensor is provided on the side of each accommodating chamber to detect the state of the liquid bottle in the accommodating chamber. When the sensor detects that the corresponding accommodating chamber is empty, an empty signal is generated; when the sensor detects that the corresponding accommodating chamber is loaded with the liquid bottle, a new liquid bottle loading signal is generated.

4. The diluent tank with movable positions according to claim 2 or 3, characterized in that: Each of the accommodating chambers is provided with a corresponding status indicator light. When the control unit indicates that there is no liquid in the bottle, the status indicator light turns on a first color. When the control unit receives an empty signal, the status indicator light turns on a second color. When the control center receives a signal for loading a new liquid bottle, the status indicator light turns on a third color.

5. The diluent tank with movable positions according to claim 4, characterized in that: The liquid bottle is provided with a safety line, and when the solution in the liquid bottle is lower than the safety line, the status indicator light lights up the first color accordingly.

6. The diluent tank with movable positions according to claim 1, characterized in that: A plurality of engaging members are also provided at the bottom of each of the accommodating chambers, and a plurality of the engaging members extend claws of a certain length toward the inside of the accommodating chamber; a plurality of convex ridges are provided on the side edge of the liquid bottle close to the bottom of the accommodating chamber, and the height of the claws from the bottom of the accommodating chamber is adapted to the height of the convex ridges from the bottom of the accommodating chamber; The plurality of claws are engaged with the plurality of convex ridges.

7. The diluent tank with movable positions according to claim 1, characterized in that: It also includes a mounting seat, the conveying track is laid on the mounting seat, and support plates with a certain length extend downward from both ends of the mounting seat respectively, and a fixing plate in mutual surface contact with the support plate is provided at one end of the support plate in contact with the fixing plane.

8. The diluent tank with movable positions according to claim 1, characterized in that: The diluent tank body is also provided with an electronic tag reader / writer for reading the barcode on the liquid bottle which records the type, batch number and capacity information of the liquid.

9. A chemiimmunoluminometer, comprising at least a sample library and a reagent compartment, characterized in that: It also includes a dilution liquid bin with a movable bin position as described in any one of claims 1 to 8, wherein the dilution liquid bin is used to hold a diluted reaction solution and reciprocate between a liquid bin working position and a liquid bin replacement position.

10. The chemiimmunoluminometer according to claim 9, characterized in that: The diluent tank is also used for containing a cleaning agent for cleaning the pipette needle.

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