MRI (Magnetic Resonance Imaging) compatible catheter

Abstract

The utility model relates to the field of medical instrument consumables, in particular to an MRI compatible catheter. Comprising a tube body, polyether-ether-ketone is adopted as a base material of the tube body, a plurality of markers are arranged on the tube body, the markers are located in the tube body, and dysprosium oxide is adopted as the markers. The utility model provides an MRI (Magnetic Resonance Imaging) compatible catheter which is visible under MRI scanning, small in artifact, free of radio frequency heating risk and good in operability, sensitivity and rigidity.

Description

Technical Field

[0001] This application relates to the field of medical device consumables, and particularly to an MRI-compatible catheter. Background Art

[0002] A catheter is the most basic device for vascular interventional procedures and is used to deliver interventional devices such as drugs, guidewires, coils, and stents. In the related art, catheters used in DSA guidance cannot be clearly visualized under magnetic resonance imaging (MRI). The ferromagnetic metal lining inside them appears as obvious ferromagnetic artifacts in MRI, and there is a risk of being attracted by the magnet, posing a safety hazard. Therefore, they cannot be used for MRI imaging. In the related art, the display technology of MRI-compatible vascular interventional catheters mostly uses passive tracing. Generally, markers are used at the catheter tip, or markers or materials are added to the entire catheter to enhance, reduce, or distort the T1 and / or T2-weighted MR signals relative to blood or tissue.

[0003] In the related art, Philipp K et al. used a structure of PTFE lining and stainless steel braided PEBAX™ / VESTAMID™ when manufacturing the catheter to ensure sufficient rigidity and flexibility. However, strengthening the device by braiding ferromagnetic metal not only causes ferromagnetic metal artifacts in imaging but also may cause compatibility and safety problems due to its ferromagnetic attraction. Helene C et al. made a magnetically compatible catheter based on polymers, which contains a 7-cm-long nitinol core rod. Paramagnetic iron oxide particles are adhered to the shaft end and tip of the catheter to create signal voids. The nitinol core rod is a non-ferromagnetic metal and does not pose a safety problem, but it will cause slight artifacts. Summary of the Invention

[0004] In view of this, this application provides an MRI-compatible catheter that can be visualized under MRI scanning, has small artifacts, does not have the risk of radiofrequency heating, and has good operability, sensitivity, and rigidity.

[0005] To achieve the above object, this application is implemented through the following technical solutions:

[0006] An MRI-compatible catheter, characterized in that: it includes a tube body, the tube body is made of polyetheretherketone as the base material, and several markers are provided on the tube body. The markers are located inside the tube body, and the markers use dysprosium oxide. Among them, polyetheretherketone has good toughness, stiffness, and excellent anti-torsion force, good insulation performance, excellent sliding characteristics, and extremely strong chemical and corrosion resistance. The role of dysprosium oxide is a paramagnetic substance, which can be visualized under magnetic resonance scanning to clearly show the location of the catheter.

[0007] The above-mentioned MRI-compatible catheter of the present application uses polyetheretherketone as the base material of the tube body and dysprosium oxide as the marker. The catheter is visible under MRI scanning and has good operability, sensitivity, and rigidity.

[0008] In some embodiments, the outer layer of the tube body is provided with materials such as polyamide, polyurethane, and hydrophilic coating. The middle layer of the tube body is provided with glass fiber-reinforced polymer (such as glass fiber-reinforced polyetheretherketone) and high-strength synthetic fiber (such as glass fiber). The inner layer of the tube body is mainly polytetrafluoroethylene (PTFE). Among them, the outer layer determines the shape, hardness, and friction force with the inner wall of the blood vessel of the catheter; the middle layer has a kink-resistant braided structure to prevent the guide lumen from collapsing; the inner layer has the function of reducing the frictional resistance between the interventional materials such as balloons and stents and the inner lumen of the catheter and preventing thrombus.

[0009] In some embodiments, the markers are arranged at equal intervals. The advantage of arranging at equal intervals is that it is beneficial to clarify the position of the catheter and the catheter tip, and it is convenient to measure the length of the diseased blood vessel for subsequent further treatment, such as the selection of stents for stent implantation.

[0010] In some embodiments, the distance between two adjacent markers is 1 cm. The distance L1 between the marker closest to the tip of the tube body and the tip of the tube body is 1 cm, and there are two parallel point markers. The equal-spacing setting can facilitate the clarification of the position of the catheter and the catheter tip.

[0011] From the above technical solutions, the present application has at least the following advantages and positive effects:

[0012] An MRI-compatible catheter of the present application is visible under MRI scanning and has good operability, sensitivity, and rigidity, laying a foundation for MRI-guided vascular intervention. In the future, some peripheral vascular intervention operations can be considered to be performed under MRI, such as iliac arteriography, stent implantation, etc., reducing the radiation damage to patients and doctors; it also brings hope for surgery to patients allergic to iodine contrast agents; at the same time, it can clearly show the blood vessel wall and surrounding soft tissue structures, further evaluate the patient's condition, and avoid risks such as plaque shedding. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 It is a schematic structural diagram of an embodiment of the present application;

[0014] Figure 2 It is a schematic internal structure diagram of an embodiment of the present application;

[0015] Figure 3 It is a schematic diagram of the distribution of markers in an embodiment of the present application.

[0016] Reference numerals: 1. Tube body; 2. Marker; 3. Hydrophilic coating; 4. Inner layer. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0017] To make the objectives, technical solutions and advantages of this application clearer, the following will further describe this application in detail in conjunction with the accompanying drawings. The terms used in the implementation part of this application are only used to explain the specific embodiments of this application, rather than aiming to limit this application.

[0018] Refer to Figures 1 to 3 , an embodiment of this application provides an MRI-compatible catheter, including a tube body 1. The tube body 1 uses polyetheretherketone as the base material. A number of markers 2 are provided on the tube body 1. The markers 2 are located inside the tube body 1, and the markers 2 use dysprosium oxide. Among them, polyetheretherketone has good toughness, stiffness and excellent anti-torque force, good insulation performance, excellent sliding characteristics, and extremely strong chemical and corrosion resistance. The role of dysprosium oxide is a paramagnetic substance, which can be visualized under magnetic resonance scanning to clearly show the location of the catheter.

[0019] In some embodiments, the outer layer of the tube body 1 is provided with materials such as polyamide, polyurethane and hydrophilic coating 3. The middle layer of the tube body 1 is provided with glass fiber reinforced polymer (such as glass fiber reinforced polyetheretherketone) and high-strength synthetic fiber (such as glass fiber). The inner layer 4 of the tube body 1 is mainly polytetrafluoroethylene (PTFE). Among them, the outer layer determines the shape, hardness and friction force with the inner wall of the blood vessel of the catheter; the middle layer has a fold-resistant braided structure to avoid the collapse of the guide cavity; the inner layer 4 has the effect of reducing the friction resistance between interventional materials such as balloons and stents and the inner cavity of the catheter and preventing thrombosis.

[0020] In some embodiments, the markers 2 are arranged at equal intervals. The advantage of arranging at equal intervals is that it is beneficial to clarify the location of the catheter and the catheter tip, and the length of the diseased blood vessel can be measured to provide convenience for the selection of subsequent further treatments, such as stent implantation and other stents.

[0021] In some embodiments, the distance between two adjacent markers 2 is 1 cm. The distance L1 between the marker 2 closest to the tip of the tube body 1 and the tip of the tube body 1 is 1 cm, and two parallel point markers are provided. Arranging at equal intervals can facilitate clarifying the position of the catheter and the catheter tip. The parallel two-point marker refers to the marker closest to the tip, which has two punctuation marks that are relatively close to each other, and is used to highlight this position to clarify the tip position.

[0022] Dysprosium oxide (strong paramagnetic) markers 2 are added throughout the length of the entire device to enhance the T1-weighted MR signal relative to blood or tissue, achieving passive tracer with positive contrast and enabling visualization and tracing of the catheter. At the same time, by changing the distribution and concentration of the paramagnetic compound, different sensitized catheters are obtained. Using dysprosium oxide, there are literature reports with a concentration of up to 30% by weight, and it is shown that it does not affect the mechanical properties of the catheter, namely tensile strength, smoothness and stiffness.

[0023] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the embodiments of the present application, rather than limiting them; although the embodiments of the present application have been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that they can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements on some or all of the technical features; and these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present application.

Claims

1. An MRI-compatible catheter, characterized in that: The invention comprises a tube body (1), wherein the tube body (1) uses polyetheretherketone as a base material, and a plurality of markers (2) are provided on the tube body (1), wherein the markers (2) are located inside the tube body (1), and the markers (2) use dysprosium oxide; The inner layer (4) of the tube body (1) is made of polytetrafluoroethylene, the middle layer of the tube body (1) is also provided with glass fiber reinforced polymer and high-strength synthetic fiber, and the outer layer of the tube body (1) is provided with polyamide, polyurethane and a hydrophilic coating.

2. An MRI-compatible catheter according to claim 1, characterized in that: The markers (2) are arranged at equal intervals.

3. An MRI-compatible catheter according to claim 2, characterized in that: The spacing between two adjacent markers (2) is 1 cm, the distance L1 between the marker (2) closest to the tip of the tube body (1) and the tip of the tube body (1) is 1 cm, and two parallel point markers are provided.

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