Magnetic bead liquid mixing device

Abstract

The utility model relates to the technical field of medical detection equipment, in particular to a magnetic bead liquid mixing device which comprises a reagent bin, an ultrasonic assembly, a cleaning pool and a rotating assembly, the ultrasonic assembly comprises an ultrasonic part, a conduction rod and a damping part, the ultrasonic part is connected to one end of the conduction rod, and the conduction rod is used for performing ultrasonic mixing on the magnetic bead liquid in the reagent bin; the cleaning pool is arranged on one side of the reagent bin and is used for cleaning the conduction rod; the rotating assembly is connected to the conduction rod through the damping piece. The cleaning pool is arranged on the rotating path of the conduction rod, and the rotating assembly is used for driving the conduction rod to move between the cleaning pool and the reagent bin. According to the magnetic bead liquid uniform mixing device, the cleaning pool is matched with the reagent bin, the rotating assembly can drive the ultrasonic assembly to move between the cleaning pool and the reagent bin so as to achieve the two actions of uniform mixing and cleaning, meanwhile, the damping piece is arranged, the energy loss of the conduction rod can be reduced, the structure is simple, and the using effect is good.

Description

Technical Field

[0001] The utility model relates to the technical field of medical detection equipment, in particular to a magnetic bead liquid mixing device. Background Art

[0002] Magnetic bead liquid has a wide range of applications in the biomedical field. The mixing device is used to ultrasonically mix the magnetic bead liquid to achieve uniform mixing of the reagent. However, there are some technical problems in the existing similar devices that need to be solved urgently.

[0003] First of all, there is an energy loss problem in the process of vibration energy conduction generated by the existing similar devices, resulting in a low effective power. This is because the installation and fixation position of the ultrasonic device is relatively close to the piezoelectric ceramic. During use, the vibration energy generated by the piezoelectric ceramic is easily absorbed by the fixing plate, resulting in energy loss and reduction of effective power. In addition, the existing similar devices lack a cleaning device after work, resulting in the energy conduction rod being easily contaminated, thus affecting the test results. The unwashed conduction rod may cause cross-contamination, which in turn affects the mixing effect of the magnetic bead liquid and the use effect of the reagent.

[0004] Therefore, it is necessary to improve the above problems to change the status quo. Summary of the Utility Model

[0005] The utility model provides a magnetic bead liquid mixing device, which is used to solve the problems of large vibration energy loss and easy cross-contamination due to inconvenient cleaning in the magnetic bead liquid mixing device in the prior art.

[0006] The utility model proposes a magnetic bead liquid mixing device, comprising:

[0007] A reagent bin;

[0008] An ultrasonic component, including an ultrasonic part, a conduction rod and a shock absorber. The ultrasonic part is connected to one end of the conduction rod, and the conduction rod is used to ultrasonically mix the magnetic bead liquid in the reagent bin;

[0009] A cleaning pool, arranged on one side of the reagent bin, and the cleaning pool is used to clean the conduction rod; and

[0010] A rotating component, connected to the conduction rod through the shock absorber; the cleaning pool is arranged on the rotation path of the conduction rod, and the rotating component is used to drive the conduction rod to move between the cleaning pool and the reagent bin.

[0011] According to an embodiment of the present utility model, the rotation assembly includes a rotation driving member and a connection structure. The connection structure is connected to the output end of the rotation driving member. The ultrasonic assembly further includes a fixing structure, which is detachably connected to the connection structure, and the fixing structure is connected to the conduction rod through the shock-absorbing member.

[0012] According to an embodiment of the present utility model, the fixing structure includes an upper flange and a lower flange. The upper flange is detachably connected to the lower flange, and the lower flange is connected to the connection structure. The upper flange is provided with a connection hole, the conduction rod passes through the connection hole and is spaced from the inner wall of the connection hole. The lower flange is provided with a receiving groove on the side facing the upper flange. The conduction rod passes through the lower flange and is at least partially received in the receiving groove. The shock-absorbing member is arranged between the upper flange and the conduction rod.

[0013] According to an embodiment of the present utility model, the conduction rod includes a rod portion and a limiting flange. The limiting flange surrounds the rod portion. The rod portion passes through the connection hole and is spaced from the inner wall of the connection hole, and the rod portion passes through the lower flange and extends out of the fixing structure. The limiting flange is received in the receiving groove, and the shock-absorbing member respectively abuts against the limiting flange and the upper flange. The side of the limiting flange away from the shock-absorbing member abuts against the inner wall of the receiving groove.

[0014] According to an embodiment of the present utility model, the shock-absorbing member includes a first shock-absorbing pad and a second shock-absorbing pad. The first shock-absorbing pad is sleeved on the rod portion and respectively abuts against the limiting flange and the upper flange. The second shock-absorbing pad surrounds the rod portion, and the second shock-absorbing pad is arranged between the lower flange and the connection structure.

[0015] According to an embodiment of the present utility model, the ultrasonic assembly further includes a housing, which is detachably connected to the fixing structure, and the ultrasonic element is suspended inside the housing.

[0016] According to an embodiment of the present utility model, the outer wall of the lower flange is provided with an external thread, and the inner part of the housing is provided with an internal thread. The housing and the lower flange are threadedly connected through the internal thread and the external thread.

[0017] According to an embodiment of the present utility model, the connection structure includes a connecting plate and an adapter plate. One end of the connecting plate is connected to the rotation driving member. The adapter plate is provided with an adjustment hole. The adapter plate is connected to the connecting plate through the adjustment hole, and the position of the adapter plate relative to the connecting plate is adjustable. The fixing structure is connected to the adapter plate.

[0018] According to an embodiment of the present utility model, the adjustment hole includes an oblong hole.

[0019] According to an embodiment of the present utility model, the conduction rod is of a hollow structure.

[0020] Implementing the embodiments of the present utility model has the following beneficial effects:

[0021] When using the magnetic bead liquid mixing device of this embodiment, by setting a shock-absorbing member between the conduction rod and the rotating assembly, the conduction loss between the ultrasonic member and the rotating assembly can be reduced, so as to improve the energy conduction loss of the conduction rod and thus improve the ultrasonic mixing efficiency of the ultrasonic assembly; by setting the rotating assembly to drive the ultrasonic assembly, the conduction rod can be driven to transfer between the cleaning pool and the reagent storage, and the cleaning pool can perform cleaning operations on the conduction rod, thereby improving the cleanliness of the conduction rod, avoiding cross-contamination, and having a good use effect.

[0022] In the magnetic bead liquid mixing device of this embodiment, through the cooperation of the cleaning pool and the reagent storage, the rotating assembly can drive the ultrasonic assembly to move between the cleaning pool and the reagent storage to achieve two actions of mixing and cleaning. At the same time, setting the shock-absorbing member can also reduce the energy loss of the conduction rod. The structure is simple and the use effect is good. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] In order to more clearly illustrate the technical solutions in the embodiments of the present utility model or the prior art, the following will briefly introduce the drawings required for use in the description of the embodiments or the prior art. Obviously, the following drawings are only some embodiments of the present utility model. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings.

[0024] Among them:

[0025] Figure 1 is a schematic structural diagram of the mixing device in the embodiment of the present utility model;

[0026] Figure 2 is a top view of the mixing device in the embodiment of the present utility model;

[0027] Figure 3 is a partial structural sectional view of the mixing device in the embodiment of the present utility model;

[0028] Figure 4 is Figure 3 an enlarged view of the partial A in

[0029] Reference numerals:

[0030] 10. Magnetic bead liquid mixing device; 100. Reagent bin; 200. Ultrasonic component; 210. Ultrasonic part; 220. Conduction rod; 221. Rod part; 222. Limit flange; 230. Shock absorber; 231. First shock pad; 232. Second shock pad; 240. Fixing structure; 241. Upper flange; 2411. Connection hole; 242. Lower flange; 2421. Accommodating groove; 250. Outer shell; 300. Cleaning pool; 400. Rotating component; 410. Rotation driving part; 420. Connection structure; 421. Connection plate; 422. Adapter plate; 4221. Adjustment hole. Detailed implementation manners

[0031] To make the objectives, technical solutions and advantages of the present utility model clearer, the technical solutions in the present utility model will be clearly and completely described below with reference to the accompanying drawings in the present utility model. Obviously, the described embodiments are some but not all of the embodiments of the present utility model. All other embodiments obtained by those of ordinary skill in the art without making creative efforts based on the embodiments in the present utility model fall within the protection scope of the present utility model.

[0032] Refer to Figures 1 to 4 As shown in the embodiments of the present utility model, a magnetic bead liquid mixing device 10 is provided, which includes a reagent bin 100, an ultrasonic component 200, a cleaning pool 300 and a rotating component 400; the ultrasonic component 200 includes an ultrasonic part 210, a conduction rod 220 and a shock absorber 230. The ultrasonic part 210 is connected to one end of the conduction rod 220, and the conduction rod 220 is used for ultrasonically mixing the magnetic bead liquid in the reagent bin 100; the cleaning pool 300 is arranged on one side of the reagent bin 100, and the cleaning pool 300 is used for cleaning the conduction rod 220; the rotating component 400 is connected to the conduction rod 220 through the shock absorber 230; the cleaning pool 300 is arranged on the rotation path of the conduction rod 220, and the rotating component 400 is used to drive the conduction rod 220 to move between the cleaning pool 300 and the reagent bin 100.

[0033] When using the magnetic bead liquid mixing device 10 of this embodiment, by arranging the shock absorber 230 between the conduction rod 220 and the rotating component 400, the conduction loss between the ultrasonic part 210 and the rotating component 400 can be reduced, so as to improve the energy conduction loss of the conduction rod 220 and thus improve the ultrasonic mixing efficiency of the ultrasonic component 200; by arranging the rotating component 400 to drive the ultrasonic component 200, the conduction rod 220 can be driven to transfer between the cleaning pool 300 and the reagent bin 100, and the cleaning pool 300 can perform cleaning operations on the conduction rod 220. Therefore, the cleanliness of the conduction rod 220 can be improved, cross-contamination can be avoided, and the use effect is good.

[0034] In the magnetic bead liquid mixing device 10 of this embodiment, through the cooperation of the cleaning pool 300 and the reagent warehouse 100, the rotating assembly 400 can drive the ultrasonic assembly 200 to move between the cleaning pool 300 and the reagent warehouse 100, so as to realize the two actions of mixing and cleaning. At the same time, the shock absorber 230 is arranged to reduce the energy loss of the conduction rod 220. The structure is simple and the use effect is good.

[0035] In one embodiment, the rotating assembly 400 includes a rotation driving member 410 and a connection structure 420. The connection structure 420 is connected to the output end of the rotation driving member 410. The ultrasonic assembly 200 further includes a fixing structure 240. The fixing structure 240 is detachably connected to the connection structure 420, and the fixing structure 240 is connected to the conduction rod 220 through the shock absorber 230.

[0036] With this setting, by setting the connection structure 420 between the rotation driving member 410 and the ultrasonic assembly 200, during use and assembly, the corresponding specification of the connection structure 420 can be selected according to the setting position between the reagent warehouse 100 and the cleaning pool 300. Of course, when the connection structure 420 is worn, the connection structure 420 can also be replaced separately, improving the maintenance convenience and reducing the use cost; when using the magnetic bead liquid mixing device 10 of this embodiment, when it is necessary to mix the magnetic bead liquid in the reagent warehouse 100, by starting the rotation driving member 410 to drive the conduction rod 220 to move into the reagent warehouse 100, and starting the ultrasonic member 210 to make the conduction rod 220 generate ultrasonic vibration; after mixing is completed, by starting the rotation driving member 410 to drive the conduction rod 220 to move into the cleaning pool 300, the cleaning pool 300 can clean the conduction rod 220 to avoid secondary pollution of the reagent by the conduction rod 220. As Figure 2 In the shown embodiment, the cleaning pool 300 is arranged on the rotation path of the conduction rod 220, so that the conduction rod 220 can be driven by the rotating assembly 400 to move between the reagent warehouse 100 and the cleaning pool 300. Specifically, the rotation driving member 410 can be a power source with a rotation function such as a rotation motor.

[0037] Specifically, the fixing structure 240 includes an upper flange 241 and a lower flange 242. The upper flange 241 and the lower flange 242 are detachably connected, and the lower flange 242 is connected to the connection structure 420; the upper flange 241 is provided with a connection hole 2411, the conduction rod 220 passes through the connection hole 2411 and is spaced from the inner wall of the connection hole 2411. The lower flange 242 is provided with a receiving groove 2421 on the side facing the upper flange 241. The conduction rod 220 passes through the lower flange 242 and is at least partially received in the receiving groove 2421. The shock absorber 230 is at least partially arranged between the upper flange 241 and the conduction rod 220.

[0038] When assembling the magnetic bead liquid mixing device 10 of this embodiment, first place the lower flange 242 on the connecting structure 420, then pass the conduction rod 220 through the lower flange 242 and the connecting structure 420, then set the shock absorber 230 on the conduction rod 220, and finally combine the upper flange 241 with the lower flange 242 to connect the conduction rod 220 with the fixed structure 240. When starting the ultrasonic component 210 to conduct vibration to the conduction rod 220, by setting the shock absorber 230 between the conduction rod 220 and the fixed structure 240, the loss of rigid vibration energy conduction between the conduction rod 220 and the connecting structure 420 can be reduced, and by adopting the combined structure of the upper flange 241 and the lower flange 242, it is convenient for the assembly and fixation between the ultrasonic component 200 and the rotating component 400, and the structure is simple.

[0039] In one embodiment, the conduction rod 220 includes a rod portion 221 and a limiting flange 222. The limiting flange 222 is disposed around the rod portion 221. The rod portion 221 passes through the connection hole 2411 and is spaced from the inner wall of the connection hole 2411, and the rod portion 221 passes through the lower flange 242 and extends out from the fixed structure 240; the limiting flange 222 is received in the receiving groove 2421, and at least part of the shock absorber 230 respectively abuts against the limiting flange 222 and the upper flange 241, and the side of the limiting flange 222 away from the shock absorber 230 abuts against the inner wall of the receiving groove 2421.

[0040] In this embodiment, by providing the limiting flange 222 on the outer wall of the rod portion 221 and cooperating with the receiving groove 2421 and the shock absorber 230, not only can the installation of the conduction rod 220 be positioned, but also the combined structure between the conduction rod 220 and the fixed structure 240 can be made compact, reducing the occupied space; in addition, by arranging the shock absorber 230 in the receiving groove 2421, the fixed structure 240 can also protect the shock absorber 230, thereby improving the durability and reliability of the shock absorber 230.

[0041] Furthermore, the shock absorber 230 includes a first shock pad 231 and a second shock pad 232. The first shock pad 231 is sleeved on the rod portion 221 and respectively abuts against the limiting flange 222 and the upper flange 241; the second shock pad 232 is disposed around the rod portion 221, and the second shock pad 232 is disposed between the lower flange 242 and the connecting structure 420.

[0042] It can be understood that by setting the first shock pad 231 between the conduction rod 220 and the fixed structure 240, the vibration conduction energy between the conduction rod 220 and the fixed structure 240 can be improved. By setting the second shock pad 232 between the fixed structure 240 and the connection structure 420, the vibration conduction between the connection structure 420 and the fixed structure 240 can be further reduced, thereby effectively reducing the energy loss of the vibration conduction of the conduction rod 220 to improve the ultrasonic vibration efficiency of the conduction rod 220.

[0043] In one embodiment, the ultrasonic component 200 further includes a housing 250. The housing 250 is detachably connected to the fixed structure 240, and the ultrasonic element 210 is suspended inside the housing 250.

[0044] With this setting, the housing 250 can be connected to the fixed structure 240 to protect the ultrasonic element 210, preventing the ultrasonic element 210 from being damaged due to being knocked during the operation of the magnetic bead liquid mixing device 10, thereby improving the reliability of the magnetic bead liquid mixing device 10.

[0045] Specifically, an external thread is provided on the outer wall of the lower flange 242, and an internal thread is provided inside the housing 250. The housing 250 and the lower flange 242 are threadedly connected through the internal thread and the external thread.

[0046] It can be understood that by providing an external thread on the outside of the lower flange 242 to cooperate with the internal thread of the housing 250, it is convenient to connect and fix the housing 250 and the fixed structure 240. At the same time, the connection structure between the housing 250 and the fixed structure 240 can be made compact, facilitating disassembly and assembly. In other embodiments, the housing 250 and the fixed structure 240 can also be combined through detachable connection methods such as buckles and magnetic attraction, which are not uniquely limited herein.

[0047] Furthermore, the connection structure 420 includes a connection plate 421 and a transfer plate 422. One end of the connection plate 421 is connected to the rotary drive member 410. The transfer plate 422 is provided with an adjustment hole 4221. The transfer plate 422 is connected to the connection plate 421 through the adjustment hole 4221, and the position of the transfer plate 422 relative to the connection plate 421 is adjustable. The fixed structure 240 is connected to the transfer plate 422.

[0048] In this embodiment, by providing the adjustment hole 4221 on the transfer plate 422 to cooperate with the connection plate 421, when the transfer plate 422 is connected to the connection plate 421, the fastener passes through the adjustment hole 4221 and is connected to the connection plate 421. By adjusting the relative position between the adjustment hole 4221 and the fastener, the relative position between the transfer plate 422 and the connection plate 421 can be adjusted to adjust the overall length of the connection structure 420.

[0049] In one embodiment, the adjustment hole 4221 includes an oblong hole.

[0050] With this setting, when the fastener is passed through the adjustment hole 4221 and connected to the connecting plate 421, the adapter plate 422 can adjust the relative position between the adapter plate 422 and the connecting plate 421 along the length direction of the waist-shaped hole through the cooperation between the adjustment hole 4221 and the fastener; of course, in other embodiments, the adjustment hole 4221 can also be a combined structure of multiple holes. By connecting the different adjustment holes 4221 to the connecting plate 421, the relative position between the adapter plate 422 and the connecting plate 421 can be adjusted, and no unique limitation is made here.

[0051] In one embodiment, the conduction rod 220 is of a hollow structure.

[0052] It can be understood that by adopting the hollow-structured conduction rod 220, the contact area between the conduction rod 220 and the magnetic bead liquid can be increased, thereby improving the mixing efficiency of the conduction rod 220.

[0053] In the description of the embodiments of the present invention, it should be noted that the orientation or positional relationship indicated by the terms "center", "longitudinal", "transverse", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the embodiments of the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation to the embodiments of the present invention. In addition, the terms "first", "second", "third" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance.

[0054] In the description of the embodiments of the present invention, it should be noted that unless otherwise clearly specified and limited, the terms "connected" and "connection" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium. For those of ordinary skill in the art, the specific meanings of the above terms in the embodiments of the present invention can be understood according to specific circumstances.

[0055] In the embodiments of the present utility model, unless otherwise clearly defined and limited, the first feature being "on" or "under" the second feature may be that the first and second features are in direct contact, or the first and second features are indirectly in contact through an intermediate medium. Moreover, the first feature being "above", "over" and "on top of" the second feature may be that the first feature is directly above or obliquely above the second feature, or merely indicates that the horizontal height of the first feature is higher than that of the second feature. The first feature being "under", "below" and "beneath" the second feature may be that the first feature is directly below or obliquely below the second feature, or merely indicates that the horizontal height of the first feature is less than that of the second feature.

[0056] In the description of this specification, the description of reference terms such as "an embodiment", "some embodiments", "example", "specific example", or "some examples", etc. means that the specific features, structures, materials, or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the embodiments of the present utility model. In this specification, the schematic representations of the above terms are not necessarily directed to the same embodiment or example. Moreover, the specific features, structures, materials, or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, without contradiction, those skilled in the art can combine and combine the different embodiments or examples described in this specification and the features of different embodiments or examples.

[0057] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present utility model, rather than to limit them; although the present utility model has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements for some of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the embodiments of the present utility model.

Claims

1. A magnetic bead liquid mixing device, characterized in that: include: Reagent tank; An ultrasonic component, comprising an ultrasonic component, a conductive rod and a shock-absorbing component, wherein the ultrasonic component is connected to one end of the conductive rod, and the conductive rod is used to ultrasonically mix the magnetic bead liquid in the reagent compartment; A cleaning tank, disposed on one side of the reagent compartment, and used for cleaning the conductive rod; as well as A rotating assembly connected to the conducting rod via the shock absorbing member; The cleaning pool is arranged on the rotation path of the conductive rod, and the rotating assembly is used to drive the conductive rod to move between the cleaning pool and the reagent chamber.

2. The magnetic bead liquid mixing device according to claim 1, characterized in that: The rotating component includes a rotating driving member and a connecting structure, wherein the connecting structure is connected to the output end of the rotating driving member. The ultrasonic component also includes a fixing structure, which is detachably connected to the connecting structure, and the fixing structure is connected to the conductive rod through the shock absorbing member.

3. The magnetic bead liquid mixing device according to claim 2, characterized in that: The fixing structure includes an upper flange and a lower flange, the upper flange is detachably connected to the lower flange, and the lower flange is connected to the connecting structure; the upper flange is provided with a connecting hole, the conduction rod is passed through the connecting hole and is spaced apart from the inner wall of the connecting hole, the lower flange is provided with a receiving groove on a side facing the upper flange, the conduction rod is passed through the lower flange and is at least partially received in the receiving groove, and the shock absorber is at least partially arranged between the upper flange and the conduction rod.

4. The magnetic bead liquid mixing device according to claim 3, characterized in that: The conduction rod includes a rod portion and a limiting flange, the limiting flange is arranged around the rod portion, the rod portion is passed through the connecting hole and is spaced apart from the inner wall of the connecting hole, and the rod portion is passed through the lower flange and extends from the fixing structure; the limiting flange is accommodated in the accommodating groove, and the shock absorbing member at least partially abuts against the limiting flange and the upper flange respectively, and the side of the limiting flange away from the shock absorbing member abuts against the inner wall of the accommodating groove.

5. The magnetic bead liquid mixing device according to claim 4, characterized in that: The shock absorbing member includes a first shock absorbing pad and a second shock absorbing pad, wherein the first shock absorbing pad is sleeved on the rod portion and respectively abuts against the limiting flange and the upper flange; the second shock absorbing pad is arranged around the rod portion, and the second shock absorbing pad is arranged between the lower flange and the connecting structure.

6. The magnetic bead liquid mixing device according to claim 3, characterized in that: The ultrasonic component also includes a shell, which is detachably connected to the fixed structure, and the ultrasonic component is suspended inside the shell.

7. The magnetic bead liquid mixing device according to claim 6, characterized in that: The outer wall of the lower flange is provided with an external thread, the interior of the outer shell is provided with an internal thread, and the outer shell and the lower flange are threadedly connected via the internal thread and the external thread.

8. The magnetic bead liquid mixing device according to claim 2, characterized in that: The connecting structure includes a connecting plate and an adapter plate, one end of the connecting plate is connected to the rotating drive member, the adapter plate is provided with an adjustment hole, the adapter plate is connected to the connecting plate through the adjustment hole, and the position of the adapter plate relative to the connecting plate is adjustable, and the fixed structure is connected to the adapter plate.

9. The magnetic bead liquid mixing device according to claim 8, characterized in that: The adjustment hole comprises a waist-shaped hole.

10. The magnetic bead liquid mixing device according to claim 1, characterized in that: The conductive rod is a hollow structure.

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