Vibrating type medicine intermediate centrifugal granulating and coating equipment
By designing cleaning rollers, cleaning plates and rotating mechanisms in vibrating pharmaceutical intermediate centrifugal granulation coating equipment, the problem of large amounts of raw materials attached to the inner wall of the raw material mixing device in the prior art is solved, and the continuous use of the equipment and the improvement of the mixing effect is achieved.
Patent Information
- Application Number
- CN202420748514.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-12
- Publication Date
- 2025-05-27
- Estimated Expiration
- 2034-04-12
AI Technical Summary
When using the existing raw material mixing device, due to the single mixing method, a large amount of raw materials are attached to the inner arm, which is not conducive to continuous use.
A vibrating pharmaceutical intermediate centrifugal granulation coating equipment is designed, using components such as cleaning rollers, cleaning plates, rotating mechanisms and impact mechanisms. Through the rotation of the cleaning rollers and the adjustment of the cleaning plate, the inner wall of the mixing chamber is cleaned to avoid the attachment of raw materials.
The inner wall of the mixing chamber is effectively cleaned, preventing raw materials from adhering, extending the service life of the equipment, and improving the mixing effect.
Smart Images
Figure CN222901014U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of granulation and coating equipment, in particular to a vibration type centrifugal granulation and coating equipment for pharmaceutical intermediates. Background Art
[0002] Vibration type centrifugal granulation coating equipment for pharmaceutical intermediates is a kind of equipment used to prepare drug particles. It combines the principles of vibration and centrifugation. Through vibration and centrifugation, the drug intermediates are wrapped in a thin film to form granular drugs. Vibration type centrifugal granulation coating equipment for pharmaceutical intermediates has the advantages of simple operation, good granulation effect, uniform coating, etc. It is widely used in the industrial production of granular drugs. When coating drugs, the vibration type centrifugal granulation coating equipment for pharmaceutical intermediates needs to go through multiple steps for processing, and the first step is to mix the raw materials.
[0003] However, when some existing raw material mixing devices are in use, because the mixing method is usually relatively simple, a large amount of raw materials will be attached to the inner arm of the mixing device, which is not conducive to continuous use. Therefore, this problem needs to be solved. Utility Model Content
[0004] The utility model aims to solve the shortcomings in the prior art and proposes a vibration type centrifugal granulation coating equipment for pharmaceutical intermediates.
[0005] In order to achieve the above purpose, the utility model adopts the following technical solutions:
[0006] A vibration-type centrifugal granulation and coating equipment for pharmaceutical intermediates comprises a mixing bin, the top of the mixing bin is fixedly connected to a motor, the motor output shaft is fixedly connected to a first rotating shaft, the surface of the first rotating shaft is symmetrically provided with two collars, the surfaces of the two collars are fixedly connected to four connecting rods, the four connecting rods are arranged in groups of two, each group of the connecting rods is fixedly connected to a support rod on the surface of a side away from the first rotating shaft, each group of the support rods are rotatably connected with cleaning rollers, the top of each group of the cleaning rollers is provided with a rotating mechanism for rotating the cleaning rollers, each group of the support rods is slidably connected with a cleaning plate, the top of each group of the cleaning plates is provided with an adjustment mechanism for adjusting the cleaning plate, the surface of the first rotating shaft close to the motor is symmetrically fixedly connected with two supporting columns, the surfaces of the two support columns are away from the first rotating shaft and are provided with an impact mechanism for impacting the mixing bin, and the inner wall of the mixing bin can be cleaned by the arrangement of the cleaning rollers.
[0007] As a further solution of the utility model, the rotating mechanism includes a second rotating shaft, which is rotatably connected to the top of the cleaning roller. A gear is provided on the surface of the second rotating shaft away from the cleaning roller. A gear ring is provided on the surface of the gear, and the gear ring is fixedly connected to the top side of the mixing chamber. Through the setting of the gear, the cleaning roller can rotate on its own.
[0008] As a further scheme of the utility model, the adjusting mechanism includes two limit rods, the two limit rods are fixedly connected between the two support rods, the cleaning plate is sleeved on the surfaces of the two limit rods, the top of the cleaning plate is fixedly connected with an adjusting plate, the top of the mixing bin close to the adjusting plate is fixedly connected with five first extrusion blocks, the five first extrusion blocks are evenly fixed in a ring shape, the five first extrusion blocks cooperate with the adjusting plate, two first springs are fixedly connected to the surface of the adjusting plate close to the support rod, the bottoms of the two first springs are fixedly connected to the top of the support rod, and the cleaning plate can be adjusted by setting the first extrusion blocks.
[0009] As a further scheme of the utility model, the impact mechanism includes a storage groove, which is opened on one side of the supporting column, a sliding rod is slidably connected inside the storage groove, an end of the sliding rod close to the storage groove is fixedly connected to a second spring, the other end of the second spring is fixedly connected to one side of the storage groove, and an impact head is fixedly connected to the end of the sliding rod away from the second spring, an adjusting column is fixedly connected to the surface of the sliding rod close to the motor, four second extrusion blocks are fixedly connected to the top of the mixing bin close to the adjusting column, the four second extrusion blocks are evenly opened in a ring shape, and the four second extrusion blocks cooperate with the adjusting column, a feed port is opened on the top of the mixing bin, four stirring rods are symmetrically fixedly connected to the surface of the first rotating shaft, and two scrapers are symmetrically fixedly connected to the surface of the first rotating shaft away from the motor, and the impact head can be made to impact the mixing bin through the setting of the adjusting column.
[0010] The beneficial effects of the utility model are:
[0011] 1. The inner wall of the mixing bin can be cleaned by setting a cleaning roller. Cleaning rollers are installed on both sides of the first rotating shaft. When the cleaning rollers are in contact with the inner wall of the mixing bin, the inner wall of the mixing bin can be cleaned when the cleaning rollers rotate along with the first rotating shaft. A gear is installed on the top of the cleaning roller, and the gear cooperates with the gear ring. With the cooperation of the gear ring, when the cleaning rollers rotate along with the first rotating shaft, they can also rotate on their own, thereby achieving a better cleaning effect.
[0012] 2. The cleaning roller can be cleaned by setting a cleaning plate. A cleaning plate is installed on one side of the cleaning roller, so that when the cleaning roller contacts the cleaning plate, the cleaning plate can bounce off the raw materials attached to the surface of the cleaning roller, so that the cleaning roller is always in the best condition. BRIEF DESCRIPTION OF THE DRAWINGS
[0013] Figure 1 This is a schematic diagram of the overall structure of a vibration-type centrifugal granulation and coating equipment for pharmaceutical intermediates proposed by the utility model;
[0014] Figure 2 This is a schematic diagram of the internal structure of a vibration-type centrifugal granulation and coating equipment for pharmaceutical intermediates proposed by the utility model;
[0015] Figure 3 This is a schematic diagram of the rotating mechanism of a vibration-type centrifugal granulation and coating equipment for pharmaceutical intermediates proposed by the utility model;
[0016] Figure 4 for Figure 3 A schematic diagram of the structure of part A;
[0017] Figure 5 This is a schematic diagram of the regulating mechanism of a vibration-type centrifugal granulation and coating equipment for pharmaceutical intermediates proposed by the utility model;
[0018] Figure 6 The utility model discloses a schematic diagram of an impact mechanism of a vibration-type centrifugal granulation and coating device for pharmaceutical intermediates.
[0019] In the figure: 1. mixing bin; 2. motor; 3. cleaning plate; 4. support column; 101. feed port; 201. first rotating shaft; 202. stirring rod; 203. scraper; 204. collar; 205. connecting rod; 206. support rod; 207. second rotating shaft; 208. cleaning roller; 209. gear ring; 210. gear; 301. limit rod; 302. adjusting plate; 303. first spring; 304. first extrusion block; 401. storage slot; 402. slide rod; 403. impact head; 404. adjusting column; 405. second extrusion block; 406. second spring. DETAILED DESCRIPTION
[0020] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.
[0021] It should be noted that, in the absence of conflict, the embodiments and features in the embodiments of the present application can be combined with each other. The present utility model will be described in detail below with reference to the accompanying drawings and in combination with the embodiments.
[0022] Reference Figure 1-Figure 6 A vibration-type centrifugal granulation coating device for pharmaceutical intermediates comprises a mixing bin 1, a motor 2 is fixedly connected to the top of the mixing bin 1, a first rotating shaft 201 is fixedly connected to the output shaft of the motor 2, two collars 204 are symmetrically sleeved on the surface of the first rotating shaft 201, four connecting rods 205 are fixedly connected to the surfaces of the two collars 204, the four connecting rods 205 are arranged in groups of two, and each group of connecting rods 205 is fixedly connected to a support rod 206 on the surface away from the first rotating shaft 201, and each group of support rods 206 are rotatably connected to each other. Cleaning rollers 208, each group of cleaning rollers 208 is provided with a rotating mechanism on the top for rotating the cleaning rollers 208, each group of support rods 206 is slidably connected with a cleaning plate 3, each group of cleaning plates 3 is provided with an adjustment mechanism on the top for adjusting the cleaning plate 3, the first rotating shaft 201 is symmetrically fixedly connected to the surface of the motor 2 on one side, and the two support columns 4 are provided with an impact mechanism on the surface of the mixing bin 1 away from the first rotating shaft 201. By setting the cleaning rollers 208, the inner wall of the mixing bin 1 can be cleaned.
[0023] Reference Figure 3 and Figure 4 In a preferred embodiment, the rotating mechanism includes a second rotating shaft 207, which is rotatably connected to the top of the cleaning roller 208. A gear 210 is sleeved on the surface of the second rotating shaft 207 away from the cleaning roller 208. A gear ring 209 is matched on the surface of the gear 210. The gear ring 209 is fixedly connected to the top side of the mixing chamber 1. Through the setting of the gear 210, the cleaning roller 208 can rotate.
[0024] Reference Figure 3-Figure 5 In a preferred embodiment, the adjustment mechanism includes two limit rods 301, and the two limit rods 301 are fixedly connected between the two support rods 206. The cleaning plate 3 is sleeved on the surfaces of the two limit rods 301, and the top of the cleaning plate 3 is fixedly connected with an adjustment plate 302. Five first extrusion blocks 304 are fixedly connected to the top of the mixing bin 1 close to the adjustment plate 302. The five first extrusion blocks 304 are evenly fixed in a ring shape, and the five first extrusion blocks 304 cooperate with the adjustment plate 302. Two first springs 303 are fixedly connected to the surface of the adjustment plate 302 close to the support rod 206, and the bottoms of the two first springs 303 are fixedly connected to the top of the support rod 206. The cleaning plate 3 can be adjusted by setting the first extrusion blocks 304.
[0025] Reference Figure 2 and Figure 6In a preferred embodiment, the impact mechanism includes a storage groove 401, the storage groove 401 is opened on one side of the support column 4, a slide rod 402 is slidably connected inside the storage groove 401, the end of the slide rod 402 close to the storage groove 401 is fixedly connected to the second spring 406, the other end of the second spring 406 is fixedly connected to one side of the storage groove 401, the end of the slide rod 402 away from the second spring 406 is fixedly connected to the impact head 403, and the surface of the slide rod 402 close to the motor 2 is fixedly connected to the adjusting column 404, the mixed Four second extrusion blocks 405 are fixedly connected to the top of the inner side of the bin 1 close to the adjusting column 404. The four second extrusion blocks 405 are evenly arranged in a ring shape, and the four second extrusion blocks 405 cooperate with the adjusting column 404. A feed port 101 is provided on the top of the mixing bin 1. Four stirring rods 202 are symmetrically fixedly connected to the surface of the first rotating shaft 201. Two scrapers 203 are symmetrically fixedly connected to the surface of the first rotating shaft 201 away from the motor 2. Through the setting of the adjusting column 404, the impact head 403 can impact the mixing bin 1.
[0026] From the above description, it can be seen that the above-mentioned embodiment of the utility model achieves the following technical effects: a motor 2 is installed on the top of the mixing bin 1. When the raw materials are mixed in the mixing bin 1, the motor 2 will start accordingly. A first rotating shaft 201 is installed on the output shaft of the motor 2. Cleaning rollers 208 are installed on both sides of the first rotating shaft 201. When the cleaning roller 208 is in contact with the inner wall of the mixing bin 1, when the cleaning roller 208 rotates with the first rotating shaft 201, the inner wall of the mixing bin 1 can be cleaned. A gear 210 is installed, and the gear 210 cooperates with the gear ring 209, so that under the cooperation of the gear ring 209, when the cleaning roller 208 follows the first rotating shaft 201 to rotate, it can also rotate on its own, so that its cleaning effect can be better. A cleaning plate 3 is installed on one side of the cleaning roller 208, so that when the cleaning roller 208 contacts the cleaning plate 3, the cleaning plate 3 can bounce off the raw materials attached to the surface of the cleaning roller 208, so that the cleaning roller 208 is always in the best state. An adjustment plate 302 is installed on the top of the cleaning plate 3, and the adjustment plate 302 cooperates with the first extrusion block 304. Due to the shape of the first extrusion block 304, when the adjustment plate 302 contacts the first extrusion block 304, the adjustment plate 302 can be moved downward. A first spring 303 is also installed at the bottom of the adjustment plate 302. With the help of the first spring 303, when the adjustment plate 302 does not contact the first extrusion block 304, it will quickly reset, so that the cleaning plate 3 enters a shaking state, thereby shaking off the raw materials on its surface. A sliding rod is also installed on the surface of the first rotating shaft 201. 402, an adjusting column 404 is installed on the surface of the slide bar 402, and the adjusting column 404 cooperates with the second extrusion block 405. When the second extrusion block 405 contacts the adjusting column 404, the slide bar 402 will move backward, but when the second extrusion block 405 does not contact the adjusting column 404, the slide bar 402 will quickly reset, and an impact head 403 is installed at one end of the slide bar 402, so that the impact head 403 can impact the mixing bin 1 to make it vibrate, and the vibration can make the raw materials better mixed.
[0027] For ease of description, spatially relative terms such as "above", "above", "on the upper surface of", "above", etc. may be used here to describe the spatial positional relationship between a device or feature and other devices or features as shown in the figure. It should be understood that spatially relative terms are intended to include different orientations of the device in use or operation in addition to the orientation described in the figure. For example, if the device in the accompanying drawings is inverted, the device described as "above other devices or structures" or "above other devices or structures" will be positioned as "below other devices or structures" or "below other devices or structures". Thus, the exemplary term "above" can include both "above" and "below". The device can also be positioned in other different ways (rotated 90 degrees or in other orientations), and the spatially relative descriptions used here are interpreted accordingly.
[0028] It should be noted that the terms used herein are only for describing specific embodiments and are not intended to limit the exemplary embodiments according to the present application. As used herein, unless the context clearly indicates otherwise, the singular form is also intended to include the plural form. In addition, it should be understood that when the terms "comprise" and / or "include" are used in this specification, it indicates the presence of features, steps, operations, devices, components and / or combinations thereof.
[0029] It should be noted that the terms "first", "second", etc. in the specification and claims of the present application and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. It should be understood that the data used in this way can be interchangeable where appropriate, so that the embodiments of the present application described herein can be implemented in an order other than those illustrated or described herein, for example. In addition, the terms "including" and "having" and any of their variations are intended to cover non-exclusive inclusions, for example, a process, method, system, product or device that includes a series of steps or units is not necessarily limited to those steps or units that are clearly listed, but may include other steps or units that are not clearly listed or inherent to these processes, methods, products or devices.
[0030] The above description is only the preferred embodiment of the utility model, and is not intended to limit the utility model. For those skilled in the art, the utility model can have various modifications and changes. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included in the protection scope of the utility model.
Claims
1. A vibrating centrifugal granulation and coating device for pharmaceutical intermediates, comprising a mixing chamber (1), characterized in that: The top of the mixing bin (1) is fixedly connected to a motor (2), the output shaft of the motor (2) is fixedly connected to a first rotating shaft (201), the surface of the first rotating shaft (201) is symmetrically sleeved with two collars (204), the surfaces of the two collars (204) are fixedly connected to four connecting rods (205), the four connecting rods (205) are arranged in groups of two, the surface of each group of connecting rods (205) away from the first rotating shaft (201) is fixedly connected to a support rod (206), and each group of support rods (206) are rotatably connected to each other. A cleaning roller (208) is connected, and a rotating mechanism for rotating the cleaning roller (208) is provided on the top of each group of the cleaning rollers (208); a cleaning plate (3) is slidably connected between each group of the support rods (206), and an adjusting mechanism for adjusting the cleaning plate (3) is provided on the top of each group of the cleaning plates (3); two supporting columns (4) are symmetrically fixedly connected to the surface of the first rotating shaft (201) close to the motor (2), and the surfaces of the two supporting columns (4) away from the first rotating shaft (201) are provided with an impact mechanism for impacting the mixing chamber (1).
2. The vibration type centrifugal granulation coating equipment for pharmaceutical intermediates according to claim 1, characterized in that: The rotating mechanism comprises a second rotating shaft (207), the second rotating shaft (207) being rotatably connected to the top of the cleaning roller (208), a gear (210) being sleeved on the surface of the second rotating shaft (207) away from the cleaning roller (208), the surface of the gear (210) being matched with a gear ring (209), and the gear ring (209) being fixedly connected to the top side of the mixing bin (1).
3. The vibration type centrifugal granulation coating equipment for pharmaceutical intermediates according to claim 2, characterized in that: The adjustment mechanism comprises two limit rods (301), the two limit rods (301) are fixedly connected between the two support rods (206), the cleaning plate (3) is sleeved on the surfaces of the two limit rods (301), the top of the cleaning plate (3) is fixedly connected with an adjustment plate (302), the top of the mixing bin (1) close to the adjustment plate (302) is fixedly connected with five first extrusion blocks (304), the five first extrusion blocks (304) are evenly fixed in a ring shape, the five first extrusion blocks (304) are mutually matched with the adjustment plate (302), the surface of the adjustment plate (302) close to the support rod (206) is fixedly connected with two first springs (303), the bottoms of the two first springs (303) are fixedly connected to the top of the support rod (206).
4. The vibration type centrifugal granulation coating equipment for pharmaceutical intermediates according to claim 3, characterized in that: The impact mechanism comprises a receiving groove (401), wherein the receiving groove (401) is opened on one side of the support column (4), a sliding rod (402) is slidably connected inside the receiving groove (401), a second spring (406) is fixedly connected to an end of the sliding rod (402) close to one side of the receiving groove (401), and the other end of the second spring (406) is fixedly connected to one side inside the receiving groove (401).
5. According to the vibration-type centrifugal granulation and coating equipment for pharmaceutical intermediates according to claim 4, the end of the sliding rod (402) away from the second spring (406) is fixedly connected to the impact head (403), the surface of the sliding rod (402) close to the motor (2) is fixedly connected to the adjustment column (404), and the inner top of the mixing bin (1) close to the adjustment column (404) is fixedly connected to four second extrusion blocks (405), the four second extrusion blocks (405) are evenly arranged in a ring shape, and the four second extrusion blocks (405) cooperate with the adjustment column (404).
6. The vibration type centrifugal granulation and coating equipment for pharmaceutical intermediates according to claim 5, characterized in that: A feed port (101) is provided on the top of the mixing bin (1); four stirring rods (202) are symmetrically fixedly connected to the surface of the first rotating shaft (201); and two scrapers (203) are symmetrically fixedly connected to the surface of the first rotating shaft (201) on the side away from the motor (2).