Liquid injection equipment of matching device of liquid injection pump for microfluidic system
By designing automated liquid injection equipment, using machines, liquid injection machines, fixtures and drive mechanisms, the problem of low efficiency of the supporting devices of the liquid injection pump for microfluidic control system when adding reagents is solved, and efficient automatic reagent addition is achieved.
Patent Information
- Application Number
- CN202421695099.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-17
- Publication Date
- 2025-05-27
- Estimated Expiration
- 2034-07-17
AI Technical Summary
The supporting device of the injection pump for microfluidic control system is inefficient when adding reagents and requires manual operation, resulting in low installation efficiency.
A liquid injection device is designed, including a machine, a liquid injection machine, a fixture and a driving mechanism. Reagents are added to multiple sample filling holes in sequence through automated means, improving the sample filling efficiency.
Automatic addition of reagents to multiple sample loading wells is realized, which improves the sample loading efficiency and ensures that the amount of reagent added in each sample loading well meets the requirements.
Smart Images

Figure CN222901130U_ABST
Abstract
Description
Technical Field
[0001] The present disclosure relates to the field of biochemical analysis equipment, and particularly to a liquid injection device for a supporting device of a liquid injection pump for a microfluidic system. Background Art
[0002] Microfluidics is a system that uses microchannels to process or manipulate tiny fluids. Microfluidics can achieve a series of microfabrications and micro-operations that are difficult to complete by conventional methods. Currently, microfluidic chips have been widely used in technical fields such as digital PCR and gene sequencing. Among them, the liquid injection pump (syringe pump) in the microfluidic system is an important device for pushing or extracting the liquid sample to be transferred. And the driving device of the pump among them is a key factor directly affecting the pushing and extracting pressure and the liquid delivery accuracy.
[0003] Chinese Patent Publication No. 202010097159.5 discloses a driving device for a liquid injection pump for a microfluidic system, which forms a liquid injection pump for a microfluidic system together with 5 sets of supporting devices. The supporting device is fixed near the liquid injection port of the microfluidic chip by a buckle 511. The supporting device includes a housing 505. A sample addition hole is provided at the top of one end of the housing 505, and the sample addition hole is blocked by a sample addition hole cover 508.
[0004] In the above solution, the housings of the 5 sets of supporting devices can be formed as an integral part or assembled together, and a total of 5 sample addition holes are included. Before use, reagents are added by manual operation. During the operation process, the pipette needs to be used to extract the reagent first and then inject it into the supporting device. The main problem is the low efficiency of manual installation. Summary of the Utility Model
[0005] Based on this, it is necessary to propose a liquid injection device for a supporting device of a liquid injection pump for a microfluidic system to solve the problems of inconvenient reagent addition and low efficiency of the supporting device of the liquid injection pump for the microfluidic system.
[0006] According to one aspect of the present disclosure, a liquid injection device for a supporting device of a liquid injection pump for a microfluidic system, the supporting device includes a housing, and a plurality of sampling holes are provided at one end of the housing. The liquid injection device includes a machine platform, and the following are provided on the tabletop of the machine platform: a liquid injector, the liquid injector includes a liquid injection gun capable of lifting in a first direction, and a driving component for driving the liquid injection gun to lift, the first direction being perpendicular to the tabletop; a fixture, the fixture includes a base and a sliding seat, the base is fixed on the tabletop, the sliding seat is used for placing the supporting device, and the sliding seat is slidably assembled on the base in a second direction to drive the sampling hole to move below the liquid injection gun, the second direction being perpendicular to the first direction; and a driving mechanism, an output part of the driving mechanism is connected to the sliding seat, and the driving mechanism is used for driving the sliding seat to slide relative to the base in the second direction; the liquid injection device further includes a control system for controlling the operation of the liquid injector and the driving mechanism.
[0007] In some embodiments, the liquid injector further includes a support structure and a sliding component, the driving component is installed on the support structure, an output end of the driving component is connected to the sliding component, and the sliding component is slidably engaged with the support structure in the first direction and is connected to the liquid injection gun.
[0008] In some embodiments, the support structure includes a horizontal plate and a vertical plate connected to each other, the horizontal plate is fixed to the tabletop, the vertical plate is arranged in the first direction, and both the sliding component and the driving component are arranged on the vertical plate.
[0009] In some embodiments, guide rails and the driving component are respectively provided on opposite sides of the vertical plate; the sliding component includes a sliding plate, a connecting plate, and a support plate, the sliding plate is slidably connected to the guide rail, the connecting plate is located above the vertical plate and both ends of the connecting plate are respectively connected to the sliding plate and the output end of the driving component, and the support plate is connected to the sliding plate; the liquid injection gun is arranged on the support plate.
[0010] In some embodiments, in a third direction, the sliding seat has a first end close to the liquid injector and a second end far from the liquid injector, the third direction being perpendicular to both the first direction and the second direction at the same time; the top surface of the sliding seat is inclined, and in the first direction, the second end is located below the first end.
[0011] In some embodiments, a limiting plate is provided at the second end of the sliding seat in the third direction.
[0012] In some embodiments, baffles are respectively provided at both ends of the sliding seat in the second direction, the third direction being perpendicular to both the first direction and the second direction at the same time.
[0013] In some embodiments, a trigger member is connected to the sliding seat, and a detection unit is further provided on the tabletop. In response to the sliding of the sliding seat along the second direction, the detection unit is triggered and sends a position signal of the sliding seat in the second direction to the control system. The control system controls the operation of the liquid injection machine and the driving mechanism according to the position signal, so that each sample addition hole can move to the lower part of the liquid injection gun in sequence, and the liquid injection gun adds reagents into the sample addition hole.
[0014] In some embodiments, the detection unit includes a first induction switch and a second induction switch that are spaced apart along the second direction.
[0015] In some embodiments, in the third direction, the detection unit is provided on a side of the fixture away from the liquid injection machine, and the trigger member is detachably connected to a side surface of the sliding seat away from the liquid injection machine, and the third direction is perpendicular to both the first direction and the second direction.
[0016] The liquid injection device can be used to automatically add reagents to a plurality of sample addition holes in sequence, thereby improving the efficiency of sample addition. Moreover, by automatically adding reagents, it can be ensured that the added amount of reagents in each sample addition hole meets the requirements. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 It is an assembly schematic diagram of a supporting device for a liquid injection pump of the microfluidic system of the present disclosure.
[0018] Figure 2 is Figure 1 an assembly schematic diagram of a screw rod piston group in the supporting device of
[0019] Figure 3 It is a structural schematic diagram of a liquid injection device of a supporting device for a liquid injection pump of the microfluidic system of the present disclosure.
[0020] Figure 4 is Figure 3 a structural schematic diagram of another perspective of the liquid injection device of , in which some components such as the machine table are hidden.
[0021] Reference Numerals:
[0022] 1. Supporting device; 101. Outer shell; 102. Screw rod piston group; 1021. Guide sleeve; 1022. Screw rod; 1023. Piston rod; 103. Sampling hole; 100. Liquid injection device; 10. Machine platform; 110. Tabletop; 20. Liquid injection machine; 210. Liquid injection gun; 220. Driving assembly; 230. Support structure; 231. Horizontal plate; 232. Vertical plate; 233. Guide rail; 240. Sliding assembly; 241. Sliding plate; 242. Connecting plate; 243. Support plate; 30. Fixture; 310. Base; 311. Guide block; 320. Sliding seat; 321. Limiting plate; 322. Baffle plate; 323. Groove; 330. Triggering part; 340. Detection unit; 341. First induction switch; 342. Second induction switch; 40. Driving mechanism; 410. Output part; 50. Control system; 60. Display screen. Detailed implementation manners
[0023] To make the above objects, features, and advantages of the present disclosure more apparent and understandable, the following will describe the detailed implementation manners of the present disclosure in conjunction with the accompanying drawings. Many specific details are set forth in the following description to fully understand the present disclosure. However, the present disclosure can be implemented in many other ways different from those described herein. Those skilled in the art can make similar improvements without departing from the connotation of the present disclosure. Therefore, the present disclosure is not limited by the specific embodiments disclosed below.
[0024] In the description of the present disclosure, it should be understood that if there are terms such as "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., the orientation or positional relationship indicated by these terms is based on the orientation or positional relationship shown in the accompanying drawings. It is only for the convenience of describing the present disclosure and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation to the present disclosure.
[0025] In addition, if there are terms such as "first" and "second", these terms are only used for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include at least one such feature. In the description of the present disclosure, if there is a term "plurality", the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise specifically defined.
[0026] An injection device 100 of a supporting device for a liquid injection pump for a microfluidic system according to an embodiment of one aspect of the present disclosure is provided. For ease of understanding, first, a brief description of the supporting device 1, which is the object to which the liquid is added in the injection device 100 of the present disclosure, is given again. Refer to Figure 1 and Figure 2 As shown, the supporting device 1 includes a housing 101 and five sets of screw rod piston groups 102 provided in the housing 101. For the specific application scenarios of the supporting device 11, reference can be made to those described in the background art, which will not be elaborated here. The housing 101 is provided with five sampling holes 103, and each sampling hole 103 corresponds to a set of screw rod piston groups 102. The screw rod piston group 102 includes a guide sleeve 1021, a screw rod 1022, and a piston rod 1023. The screw rod 1022 is rotatably installed in the guide sleeve 1021, and the screw rod 1022 is threadedly connected to the piston rod 1023. The injection device 100 of the present disclosure is used to sequentially add reagents into the five sampling holes 103. It can be understood that the number of sampling holes 103 and screw rod piston groups 102 is not limited to five, and is specifically determined according to the structural design of the microfluidic chip.
[0027] The following describes the implementation manner of the injection device 100 of the supporting device for the liquid injection pump for the microfluidic system of the present disclosure with reference to the accompanying drawings.
[0028] As Figure 3 and Figure 4 shown, the injection device 100 includes a machine table 10. An injection machine 20, a fixture 30, and a driving mechanism 40 are provided on the table surface 110 of the machine table 10. The torque testing device further includes a control system 50 for controlling the operation of the injection machine 20 and the driving mechanism 40. Optionally, the control system 50 is arranged inside the machine table 10.
[0029] The injection machine 20 includes an injection gun 210 that can be lifted and lowered in a first direction Z, and a driving component 220 that drives the injection gun 210 to lift and lower. The first direction Z is perpendicular to the table surface 110. The driving component 220 can drive the injection gun 210 to lift and lower in a first direction X, so as to be able to add reagents into the sampling hole 103, and move upward away from the sampling hole 103 after sampling to prepare for the next sampling. Figure 3 In
[0030] the first direction Z is along the vertical direction. Figure 3 In
[0031] The top of the sliding seat 320 is used to place and fix the supporting device 1. The way of fixing the supporting device 1 by the sliding seat 320 is not limited. Exemplarily, the top of the sliding seat 320 is provided with a concave-convex structure that conforms to the bottom contour shape of the outer shell 101 of the supporting device 1, so that the supporting device 1 can be embedded in the top of the sliding seat 320. Exemplarily, a fixing fixture, such as a pneumatic pressing block, is provided on the top of the sliding seat 3203, and the outer shell 101 of the supporting device 1 is pressed tightly on the sliding seat 320 by using the pneumatic pressing block.
[0032] The output part 410 of the driving mechanism 40 is connected to the sliding seat 320, and the driving mechanism 40 is used to drive the sliding seat 320 to slide relative to the base 310 along the second direction X. The type of the driving mechanism 40 is not limited, as long as it can make the sliding seat 320 move along the second direction X.
[0033] The working principle of the liquid injection device 100 is as follows: The supporting device 1 is placed and fixed on the sliding seat 320, and one end of the supporting device 1 provided with the sample adding hole 103 is close to the liquid injector 20. The control system 50 controls the operation of the liquid injector 20 and the driving mechanism 40. Among them, during the process that the driving mechanism 40 pushes the sliding seat 320 to move along the second direction X, a plurality of sample adding holes 103 can sequentially move to the lower part of the liquid injection gun 210. Then the control system 50 controls the liquid injection cavity to add reagents into the corresponding sample adding holes 103. In this way, the liquid injection device 100 can be used to automatically add reagents into a plurality of sample adding holes 103 in sequence, thereby improving the sample adding efficiency. Moreover, by automatically adding reagents, it can be ensured that the added amount of reagents in each sample adding hole 103 meets the requirements.
[0034] In some embodiments, the liquid injector 20 further includes a support structure 230 and a sliding assembly 240. The driving assembly 220 is installed on the support structure 230, the output end of the driving assembly 220 is connected to the sliding assembly 240, and the sliding assembly 240 is slidably engaged with the support structure 230 along the first direction Z and is connected to the liquid injection gun 210. In the above way, the position of the liquid injection gun 210 in the first direction Z is adjustable. The specific type of the driving assembly 220 is not limited.
[0035] Specifically, the support structure 230 includes a connected horizontal plate 231 and a vertical plate 232. The horizontal plate 231 is fixed to the table top 110, the vertical plate 232 extends along the first direction Z, and both the sliding assembly 240 and the driving assembly 220 are arranged on the vertical plate 232. The horizontal plate 231 is used to connect the table top 110, and the vertical plate 232 is used to arrange the sliding assembly 240 and the driving assembly 220. The structure of the support structure 230 is relatively simple. The horizontal plate 231 and the table top 110 can be welded or connected by bolts.
[0036] Reference Figure 3 and Figure 4, guide rails 233 and a driving assembly 220 are respectively arranged on two opposite sides of the vertical plate 232. The sliding assembly 240 includes a sliding plate 241, a connecting plate 242, and a supporting plate 243. The sliding plate 241 is slidably connected to the guide rail 233. The connecting plate 242 is located above the vertical plate 232, and two ends of the connecting plate 242 are respectively connected to the sliding plate 241 and the output end of the driving assembly 220. The supporting plate 243 is perpendicular to and connected to the sliding plate 241. The liquid injection gun 210 is arranged on the supporting plate 243. The type of the driving assembly 220 is not limited. Exemplarily, the driving assembly 220 is a linear motor.
[0037] The guide rails 233 and the driving assembly 220 are arranged on two opposite sides of the vertical plate 232. Therefore, the space on both sides of the vertical plate 232 can be fully utilized, facilitating the arrangement of the guide rails 233 and the driving assembly 220. The connecting plate 242 is located above the vertical plate 232, and the connecting plate 242 can also be used to limit the movement stroke of the sliding plate 241 when the sliding plate 241 moves downward in the first direction Z. In this way, when an accident occurs, the liquid injection gun 210 can be prevented from colliding with the outer shell 101 and being damaged.
[0038] In some embodiments, in the third direction Y, the sliding seat 320 has a first end close to the liquid injection machine 20 and a second end far from the liquid injection machine 20. The third direction Y is perpendicular to both the first direction Z and the second direction X at the same time; the top surface of the sliding seat 320 is inclined, and in the first direction Z, the second end is located below the first end.
[0039] With such an arrangement, when the supporting device 1 is placed on the sliding seat 320, the position of the end of the supporting device 1 provided with the sample addition hole 103 is higher in the first direction. In this way, on the one hand, the distance requirement for the downward movement of the liquid injection gun 210 is lower; on the other hand, since the supporting device 1 is inclined, after the reagent is added, the reagent will not leak from the sample addition hole 103.
[0040] Furthermore, in the third direction Y, a limiting plate 321 is provided at the second end of the sliding seat 320. The limiting plate 321 can limit the supporting device 1, so that the supporting device 1 will not slide off the top surface of the sliding seat 320. Moreover, the top surface of the sliding seat 320 does not need to be provided with structures for fixing the supporting device 1 such as clamping or pressing, thus simplifying the design.
[0041] Furthermore, baffles 322 are respectively arranged at two ends of the sliding seat 320 in the second direction X. In this way, the two baffles 322 limit the supporting device 1 from both sides, and the supporting device 1 can be prevented from moving in the second direction X.
[0042] In some embodiments, a groove 323 is provided at the bottom of the sliding seat 320, and the base 310 is provided with a guiding block 311 that slidably cooperates with the groove 323. In this way, the sliding seat 320 can be slidably connected to the base 310.
[0043] In some embodiments, a trigger member 330 is connected to the sliding seat 320, and a detection unit 340 is further provided on the tabletop 110. In response to the sliding of the sliding seat 320 along the second direction X, the detection unit 340 is triggered and sends a position signal of the sliding seat 320 in the second direction X to the control system 50. The control system 50 controls the driving mechanism 40 and the operation of the driving mechanism 40 according to the position signal, so that each sampling hole 103 can move to the lower side of the liquid injection gun 210 in sequence, and the liquid injection gun 210 adds reagents into the sampling hole 103. The detection unit 340 can be a contact type or a non-contact type, such as a microswitch, an optoelectronic switch, etc.
[0044] Specifically, during the process of the sliding seat 320 sliding along the second direction X, when the detection unit 340 is triggered, the first one of the plurality of sampling holes 103 is configured to move to the lower side of the liquid injection gun 210. In the present disclosure, the first one of the plurality of sampling holes 103 refers to: when the sliding seat 320 moves along the second direction and the plurality of sampling holes 103 move to the lower side of the liquid injection gun 210 in sequence, the first sampling hole 103 that moves to the lower side of the liquid injection gun 210. Exemplarily, when the driving mechanism 40 is arranged on one side of the sliding seat 320 in the second direction X, the first one of the plurality of screw rods 1022 refers to the sampling hole 103 that is farthest from the driving mechanism 40.
[0045] The timing for the other sampling holes 103 among the plurality of sampling holes 103 to move to the lower side of the liquid injection gun 210 can be set based on the spacing between adjacent sampling holes 103 in the second direction X. For example, the control system 50 controls the time interval for the sliding seat 320 to slide again along the second direction X according to the size of the spacing between adjacent sampling holes 103, so that each sampling hole 103 moves to the lower side of the liquid injection gun 210.
[0046] Specifically, in the third direction Y, the detection unit 340 is arranged on the side of the fixture 30 away from the liquid injection machine 20, the trigger member 330 is detachably connected to the side of the sliding seat 320 away from the liquid injection machine 20, and the third direction Z is perpendicular to both the first direction Z and the second direction X at the same time. The detection unit 340 is arranged on the side of the fixture 30 facing away from the liquid injection machine 20. The trigger member 330 is detachably connected to the side of the sliding seat 320 facing away from the liquid injection machine 20. Neither the detection unit 340 nor the trigger member 330 affects the up and down movement of the liquid injection gun 210 along the first direction Z.
[0047] Further, the detection unit 340 includes a first induction switch 341 and a second induction switch 342 that are spaced apart in the second direction. The first induction switch 341 and the second induction switch 342 are allocated positions to determine the starting working position of the sliding seat 320. Specifically, when the first induction switch 341 is triggered, it indicates that the first sample adding hole 103 moves below the liquid injection gun 210. When the second induction switch 342 is triggered, it indicates that the last sample adding hole 103 moves below the liquid injection gun 210.
[0048] By setting the first induction switch 341 and the second induction switch 342, the starting working position of the sliding seat 320 can be determined, thereby improving work efficiency. For example, before the first induction switch 341 is triggered, the driving mechanism 40 can drive the sliding seat 320 to move forward at a relatively fast speed. After the second induction switch 342 is triggered, the driving mechanism 40 can drive the sliding seat 320 to move backward at a relatively fast speed.
[0049] In some embodiments, a display screen 60 is further provided on the tabletop 110, and the display screen 60 is communicatively connected to the control system 50. The display screen 60 is used to display various working information, such as the position information of the sliding seat 320 in the second direction X, the working state information of the liquid injection gun 210, etc.
[0050] In the present disclosure, unless otherwise clearly specified and limited, if terms such as "installation", "connection", "connection", "fixation" appear, these terms should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or integrated; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium. It can be the communication inside two components or the interaction relationship between two components, unless otherwise clearly limited. For those of ordinary skill in the art, the specific meanings of the above terms in the present disclosure can be understood according to specific circumstances.
[0051] In the present disclosure, unless otherwise clearly specified and limited, if a first feature is described as "above" or "below" a second feature or the like, its meaning can be that the first and second features are in direct contact, or the first and second features are indirectly in contact through an intermediate medium. Moreover, the first feature being "above", "over" and "on" the second feature can mean that the first feature is directly above or obliquely above the second feature, or merely indicates that the first feature has a higher horizontal height than the second feature. The first feature being "below", "beneath" and "under" the second feature can be that the first feature is directly below or obliquely below the second feature, or merely indicates that the first feature has a lower horizontal height than the second feature.
[0052] It should be noted that if an element is referred to as "fixed to" or "disposed on" another element, it can be directly on the other element or there may be an intermediate element. If an element is considered to be "connected to" another element, it can be directly connected to the other element or there may be an intermediate element at the same time. If any, the terms "vertical", "horizontal", "upper", "lower", "left", "right" and similar expressions used in this disclosure are only for illustrative purposes and do not represent the only implementation.
[0053] The technical features of the above embodiments can be combined arbitrarily. For the sake of brevity of description, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, it should be considered as the scope described in this specification.
[0054] The above embodiments only represent several implementation manners of the present disclosure, and the description thereof is relatively specific and detailed, but it should not be construed as a limitation on the scope of the disclosed patent. It should be noted that for those of ordinary skill in the art, without departing from the concept of the present disclosure, several modifications and improvements can be made, and these all belong to the protection scope of the present disclosure. Therefore, the protection scope of the present disclosure patent shall be subject to the appended claims.
Claims
1. A liquid injection device for a microfluidic system liquid injection pump supporting device, the supporting device comprising a housing, one end of the housing is provided with a plurality of sample injection holes, characterized in that: The liquid injection equipment comprises a machine platform, on the table of the machine platform there are: A liquid injection machine, the liquid injection machine comprising a liquid injection gun capable of being raised and lowered in a first direction, and a driving assembly for driving the liquid injection gun to be raised and lowered, wherein the first direction is perpendicular to the table; A fixture, the fixture comprising a base and a sliding seat, the base being fixed on the table, the sliding seat being used to place the supporting device, the sliding seat being slidably assembled on the base along a second direction so as to drive the sample addition hole to move to below the injection gun, the second direction being perpendicular to the first direction; and a driving mechanism, wherein an output portion of the driving mechanism is connected to the sliding seat, and the driving mechanism is used to drive the sliding seat to slide relative to the base along the second direction; The liquid injection device also includes a control system for controlling the operation of the liquid injection machine and the driving mechanism.
2. The liquid injection device of the supporting device of the liquid injection pump for the microfluidic system according to claim 1, characterized in that: The injection machine also includes a supporting structure and a sliding assembly. The driving assembly is installed on the supporting structure. The output end of the driving assembly is connected to the sliding assembly. The sliding assembly can be slidably connected to the supporting structure along the first direction and is connected to the injection gun.
3. The liquid injection device of the supporting device of the liquid injection pump for the microfluidic system according to claim 2, characterized in that: The supporting structure comprises a horizontal plate and a vertical plate connected to each other, wherein the horizontal plate is fixed to the table top, the vertical plate is arranged along the first direction, and the sliding assembly and the driving assembly are both arranged on the vertical plate.
4. The liquid injection device of the supporting device of the liquid injection pump for the microfluidic system according to claim 3, characterized in that: The guide rails and the driving assembly are respectively provided on opposite sides of the vertical plate; The sliding assembly includes a sliding plate, a connecting plate, and a supporting plate. The sliding plate is slidably connected to the guide rail. The connecting plate is located above the vertical plate and both ends of the connecting plate are respectively connected to the sliding plate and the output end of the driving assembly. The supporting plate is connected to the sliding plate. The injection gun is arranged on the support plate.
5. The liquid injection device of the supporting device of the liquid injection pump for the microfluidic system according to claim 1, characterized in that: In the third direction, the sliding seat has a first end close to the injection machine and a second end away from the injection machine, and the third direction is perpendicular to both the first direction and the second direction; the top surface of the sliding seat is inclined, and in the first direction, the second end is located below the first end.
6. The liquid injection device of the supporting device of the liquid injection pump for the microfluidic system according to claim 5, characterized in that: In the third direction, a limiting plate is provided at the second end of the sliding seat.
7. The liquid injection device of the supporting device of the liquid injection pump for the microfluidic system according to claim 5, characterized in that: The sliding seat is provided with baffles at both ends of the second direction, and the third direction is perpendicular to both the first direction and the second direction.
8. The liquid injection device of the supporting device of the liquid injection pump for the microfluidic system according to claim 1, characterized in that: A trigger is connected to the sliding seat, and a detection unit is also provided on the table. In response to the sliding seat sliding along the second direction, the detection unit is triggered and sends a position signal of the sliding seat in the second direction to the control system. The control system controls the operation of the injection machine and the driving mechanism according to the position signal, so that each sample addition hole can move to the bottom of the injection gun in turn, and the injection gun adds reagents to the sample addition holes.
9. The liquid injection device of the supporting device of the liquid injection pump for the microfluidic system according to claim 8, characterized in that: The detection unit includes a first induction switch and a second induction switch which are arranged at intervals along the second direction.
10. The liquid injection device of the supporting device of the liquid injection pump for the microfluidic system according to claim 8, characterized in that: In the third direction, the detection unit is arranged on a side of the fixture away from the injection machine, and the trigger member is detachably connected to the side of the sliding seat away from the injection machine. The third direction is perpendicular to both the first direction and the second direction.
Citation Information
Patent Citations
Liquid injection pump driving device for microfluidic system
CN111250183A