Multi-channel pipetting device

Abstract

The utility model discloses and provides a multichannel pipetting device which comprises a main frame, at least one linear motion module is arranged in the main frame, each linear motion module is in transmission connection with a sliding seat, the side face of each sliding seat is fixedly connected with a Z-axis base, the Z-axis base is provided with a plurality of opening grooves which are arranged side by side, and the opening grooves are communicated with the sliding seats. Wherein a spline gear is embedded in one opening groove, the spline gear is meshed with a special-shaped rack, a pipettor is fixedly connected to one side of the special-shaped rack, a plurality of Z-axis motors are fixedly connected to one end of the main frame, and output shafts of the Z-axis motors are in transmission connection with spline shafts; the spline shafts and the spline gears are arranged in a one-to-one correspondence and meshed mode. According to the utility model, the pipettors are driven to independently move back and forth through the plurality of independently arranged linear motion modules, the pipettors are driven to lift through the spline shafts, and the plurality of pipettors can be independently driven and independently controlled, so that the use is more flexible and convenient.

Description

Technical Field

[0001] The present disclosure relates to the technical field of liquid transfer equipment, and in particular to a multi-channel liquid transfer device. Background Art

[0002] A multichannel pipetting device is a pipetting component used in an automatic pipetting platform or system. It is a device that can handle multiple liquid samples at the same time, transferring small amounts of liquid simultaneously through separate pipettes to achieve efficient liquid transfer and distribution.

[0003] In current multi-channel pipetting devices, multiple channels are raised and lowered simultaneously for pipetting operations, and cannot be individually controlled or raised and lowered independently, making them inflexible to use. Utility Model Content

[0004] The present disclosure provides a multi-channel pipetting device to solve one of the technical problems recognized by the inventor.

[0005] The present disclosure provides a multi-channel pipetting device, comprising a main frame, wherein at least one linear motion module is arranged inside the main frame, each of the linear motion modules is respectively connected to a slide seat in transmission, a side of the slide seat is fixedly connected to a Z-axis base, the Z-axis base is provided with a plurality of open grooves arranged in parallel, a spline gear is embedded in one of the open grooves, the spline gear is meshed with a special-shaped rack, a pipette is fixedly connected to one side of the special-shaped rack, one end of the main frame is fixedly connected to a plurality of Z-axis motors, an output shaft of the Z-axis motor is connected to a spline shaft in transmission, and the spline shaft corresponds to and meshes with the spline gears one by one.

[0006] Preferably, an extension plate is fixedly connected to the side of the Z-axis base, a first slider is fixedly connected to the extension plate, a first guide rail is fixedly connected to the side of the special-shaped rack, and the first slider is slidably connected to the first guide rail.

[0007] Preferably, the Z-axis motor is fixedly connected to the inner side of the main frame through a Z-axis motor mounting plate, a partition is fixedly connected to the inner side of the main frame, a damper is arranged at a position corresponding to the partition and the Z-axis motor, and the spline shaft passes through the damper.

[0008] Preferably, the side of the special-shaped rack close to the pipette is fixedly connected with a wire pressing plate, the side of the slide is fixedly connected with a pressure plate, the two sides of the top of the main frame are respectively fixedly connected with wire grooves, and cables are movably connected in the wire grooves, one end of the cable is connected to the pipette, and the cable is fixed by the wire pressing plate and the pressure plate.

[0009] Preferably, the linear motion module includes a Y-axis motor mounting plate, on the side of which several Y-axis motors are fixedly connected. The output shaft of the Y-axis motor is key-connected with a driving wheel. A plurality of tension pulleys are rotatably connected to the inner side of the main frame. The driving wheel and the tension pulleys are connected by a synchronous belt in transmission. The synchronous belt is fixedly connected with a clamping block, and the clamping blocks are respectively corresponding to and fixedly connected with the sliding seats one by one.

[0010] Preferably, several second guide rails are fixedly connected to the inner side of the main frame. Second sliders are slidably connected to the second guide rails, and the second sliders are respectively corresponding to and fixedly connected with the sliding seats one by one.

[0011] Preferably, several of the pipettes are arranged staggeredly.

[0012] Preferably, the number of the linear motion modules is four, the number of the sliding seats is four, the number of the pipettes is four, and two of the linear motion modules, sliding seats and pipettes are respectively arranged on both sides inside the main frame.

[0013] Preferably, the number of the linear motion modules is eight, the number of the sliding seats is eight, the number of the pipettes is eight, and four of the linear motion modules, sliding seats and pipettes are respectively arranged on both sides inside the main frame.

[0014] The beneficial effects of the present disclosure mainly lie in that: in the present utility model, a plurality of separately arranged linear motion modules drive the pipettes to move back and forth separately, and the pipettes are driven to lift by a spline shaft. The multiple pipettes can be driven and controlled separately, which is more flexible and convenient to use, and has a compact structure and occupies a small space.

[0015] It should be understood that both the foregoing general description and the following specific embodiments are for the purpose of illustration and example and are not necessarily restrictive of the present disclosure. The accompanying drawings incorporated in and constituting a part of this specification illustrate the subject matter of the present disclosure. At the same time, the specification and the drawings are used to explain the principles of the present disclosure. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the specific embodiments of the present disclosure or the technical solutions in the prior art, the following will briefly introduce the drawings required to be used in the description of the specific embodiments or the prior art. Obviously, the following drawings are some embodiments of the present disclosure. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0017] Figure 1 It is a schematic diagram of the overall structure of an embodiment of the present disclosure;

[0018] Figure 2The bottom view of the embodiment of the present disclosure;

[0019] Figure 3 The left-side structural schematic diagram of the embodiment of the present disclosure;

[0020] Figure 4 The left-back structural schematic diagram of the embodiment of the present disclosure;

[0021] Figure 5 The Z-axis movement structural schematic diagram of the embodiment of the present disclosure;

[0022] Icons: 1 - main frame; 11 - left side plate; 12 - right side plate; 13 - front side plate; 14 - rear side plate; 15 - bottom plate; 16 - partition board; 2 - linear motion module; 21 - Y-axis motor mounting plate; 22 - Y-axis motor; 23 - driving pulley; 24 - tensioning pulley; 25 - synchronous belt; 26 - clamping block; 27 - second linear guide rail; 28 - second slider; 3 - sliding seat; 31 - pressing plate; 41 - Z-axis base; 411 - opening groove; 412 - extension plate; 42 - special-shaped rack; 421 - first guide rail; 422 - wire pressing plate; 43 - Z-axis motor; 44 - Z-axis motor mounting plate; 45 - spline shaft; 46 - spline gear; 5 - pipette; 6 - damper; 7 - wire groove; 71 - cable. Detailed implementation manners

[0023] The technical solutions of the present disclosure will be clearly and completely described below with reference to the accompanying drawings. Apparently, the described embodiments are some, but not all, of the embodiments of the present disclosure.

[0024] All other embodiments obtained by those of ordinary skill in the art based on the embodiments in the present disclosure without creative efforts shall fall within the protection scope of the present disclosure.

[0025] In the description of the present disclosure, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present disclosure and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as a limitation to the present disclosure. In addition, the terms "first", "second", "third" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance.

[0026] In the description of the present disclosure, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present disclosure can be understood according to specific circumstances.

[0027] Example

[0028] like Figures 1-5 As shown, this embodiment provides a multi-channel pipetting device, including a main frame 1, the main frame 1 is a rectangular frame structure composed of a left side plate 11, a right side plate 12, a front side plate 13, a rear side plate 14 and a bottom plate 15, at least one linear motion module 2 is arranged inside the main frame 1, each of the linear motion modules 2 is respectively connected to a slide 3, and a Z-axis base 41 is fixedly installed with side bolts of the slide 3, and the Z-axis base 41 is sequentially provided with a plurality of parallel opening grooves 411 from top to bottom, one of which is A spline gear 46 is embedded in 411, and the spline gear 46 is rotatably connected to the open groove 411 through a bearing. The outer side of the spline gear 46 is provided with external teeth, and the outer side of the spline gear 46 is meshed with a special-shaped rack 42. The special-shaped rack 42 is bolted and fixedly connected to a pipette 5 on the side away from the spline gear 46. A Z-axis motor mounting plate 44 is bolted and fixedly installed at one end of the main frame 1. A plurality of Z-axis motors 43 are screwed and fixedly installed on the Z-axis motor mounting plate 44. The output shaft of the Z-axis motor 43 is connected to the main frame 1 through the main frame 1. A spline shaft 45 is connected through a coupling transmission, and one end of the spline shaft 45 away from the Z-axis motor 43 is rotatably connected to the rear side plate 14 through a bearing. The spline shaft 45 corresponds to and meshes with the spline gears. In this embodiment, multiple spline shafts 45 located on the same side are arranged in parallel with each other and arranged one by one from top to bottom. Each spline shaft 45 will mesh with a spline gear 46 on one of the Z-axis bases 41. Rotating the spline shaft 45 drives the spline gear 46 to rotate, and the spline gears 46 on different Z-axis bases 41 are engaged with each other. 6 is installed at different positions. The spline shaft 45 will pass through the opening groove 411 of the other Z-axis base 41, so that each of the spline shafts 45 only drives one of the spline gears to rotate, thereby realizing the separate control of one of the pipettes 5; the slide 3 is driven to move forward and backward by the linear motion module 2, and then the spline shaft 45 is driven to rotate by the Z-axis motor 43. The rotation of the spline shaft 45 drives the spline gear 46 to rotate, thereby driving the special-shaped rack 42 to move up and down, realizing the up and down movement control of the pipette 5, so as to perform the liquid aspiration or liquid discharge operation.

[0029] Specifically, an extension plate 412 is integrally formed on the side surface of the Z-axis base 41. A first slider is fixedly connected to the extension plate 412 by bolts. A first guide rail 421 is fixedly connected to the side surface of the special-shaped rack 42 by bolts. The first slider is slidably connected to the first guide rail 421. The length direction of the first guide rail 421 is parallel to the length direction of the special-shaped rack 42. The cooperation of the first guide rail 421 and the first slider plays a role in guiding and assisting installation.

[0030] Further, a partition plate 16 is fixedly connected to the inner side of the main frame 1 by bolts. The partition plate 16 is fixedly connected to the left side plate 11, the right side plate 12 and the bottom plate 15 of the main frame 1 by bolts respectively. A damper 6 is arranged at a position corresponding to the Z-axis motor 43 on the partition plate 16. The spline shaft 45 penetrates through the damper 6. In this embodiment, the damper 6 is a magnetic damper 6. The magnetic damper 6 has two directions. When the spline shaft 45 rotates in one direction, there is resistance, and when it rotates in the opposite direction, there is no resistance. Without contact, the magnetic damper 6 can prevent the pipette 5 from moving downward due to the action of gravity when power is off, playing a role of hovering.

[0031] Further, a wire pressing plate 422 is fixedly connected to one side of the special-shaped rack close to the pipette 5. A pressing plate 31 is fixedly connected to the side surface of the sliding seat 3. Wire grooves 7 are fixedly connected to both sides of the top end of the main frame 1 respectively. A cable 71 is movably connected in the wire groove 7. One end of the cable 71 is connected to the pipette 5, and the cable 71 is fixed by the wire pressing plate 422 and the pressing plate 31. Wire grooves 7 are fixedly connected to the top ends of the left side plate 11 and the right side plate 12 of the main frame 1 respectively. The cable 71 introduced from the outside is guided by the wire groove 7, passes through the pressing plate 31 and the wire pressing plate 422 respectively and then is connected to the pipette 5. The cable 71 of the pipette 5 is fixed by the pressing plate 31 and the wire pressing plate 422, ensuring that the cable 71 bends along the set route without rubbing.

[0032] Specifically, the linear motion module 2 includes a Y-axis motor mounting plate 21. A plurality of Y-axis motors 22 are fixedly connected to the side surface of the Y-axis motor mounting plate 21 by bolts. The output shaft of the Y-axis motor 22 is key-connected with a driving wheel 23. A plurality of tension pulleys 24 are rotatably connected to the inner side of the main frame 1. The driving wheel 23 and the tension pulleys 24 are connected by a synchronous belt 25 in transmission. The synchronous belt 25 is fixedly connected with a clamping block 26. The clamping blocks 26 are respectively corresponding to and fixedly connected with the sliding seats 3 one by one. By driving the driving wheel 23 to rotate through the Y-axis motor 22, the synchronous belt 25 moves to drive the sliding seat 3 to move. Each linear motion module 2 drives a sliding seat 3 to move separately, realizing the separate control of each pipette 5.

[0033] Further, a plurality of second guide rails 27 are fixedly connected to the inner sides of the left side plate 11 and the right side plate 12 of the main frame 1 by bolts. A second slider 28 is slidably connected to the second guide rail 27, and the second slider 28 corresponds to and is fixedly connected to the slide base 3 one by one. The second guide rail 27 and the second slider 28 are used for auxiliary guiding and supporting.

[0034] Further, a plurality of the pipettes 5 are arranged staggeredly. This arrangement saves space.

[0035] In one embodiment, the number of the linear motion modules 2 is four, the number of the slide bases 3 is four, the number of the pipettes 5 is four, and two of the linear motion modules 2, slide bases 3 and pipettes 5 are respectively arranged on both sides inside the main frame 1.

[0036] In one embodiment, the number of the linear motion modules 2 is eight, the number of the slide bases 3 is eight, the number of the pipettes 5 is eight, and four of the linear motion modules 2, slide bases 3 and pipettes 5 are respectively arranged on both sides inside the main frame 1.

[0037] The above are only two of the embodiments. Actually, one or more than one pipette 5 and the matching number of linear motion modules 2 can be set. Commonly, there are numbers such as 2, 4, 6, 8, 12, 16, etc., and odd channels such as 3, 5 can also be set. The above two embodiments should not be used as a limitation on the protection scope of this application.

[0038] The working principle of the present utility model: Taking eight pipettes 5 as an example, the Y-axis motor 22 drives the driving wheel 23 to rotate, drives the synchronous belt 25 to move, and thus drives the slide base 3 to move back and forth. The slide base 3 drives the pipette 5 to move back and forth. Each Y-axis motor 22 can independently drive a pipette 5 to move. After the Y-axis motor 22 drives the pipette 5 to move to the position for sucking liquid, the Z-axis motor 43 drives the spline shaft 45 to rotate, the spline shaft 45 drives the spline gear 46 to rotate, drives the special-shaped rack 42 to move up and down, and thus drives the pipette 5 to move to the liquid for liquid suction operation. Each Z-axis motor 43 can independently drive a pipette 5 to move up and down. By separately driving the pipette 5 to move back and forth and up and down by a plurality of Z-axis motors 43 and Y-axis motors 22 respectively, the liquid transfer operation is completed.

[0039] Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present disclosure, rather than to limit them; although the present disclosure has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: they can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements on some or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present disclosure.

Claims

1. A multi-channel liquid transfer device, characterized in that: include: A main frame, wherein at least one linear motion module is arranged inside the main frame, each of the linear motion modules is respectively connected to a slide seat in transmission, a Z-axis base is fixedly connected to the side of the slide seat, the Z-axis base is provided with a plurality of open grooves arranged in parallel, a spline gear is embedded in one of the open grooves, the spline gear is meshed with a special-shaped rack, a pipette is fixedly connected to one side of the special-shaped rack, and a plurality of Z-axis motors are fixedly connected to one end of the main frame, an output shaft of the Z-axis motor is connected to a spline shaft in transmission, and the spline shaft corresponds to and meshes with the spline gears one by one.

2. A multi-channel pipetting device according to claim 1, characterized in that: An extension plate is fixedly connected to the side of the Z-axis base, a first slider is fixedly connected to the extension plate, a first guide rail is fixedly connected to the side of the special-shaped rack, and the first slider is slidably connected to the first guide rail.

3. A multi-channel pipetting device according to claim 2, characterized in that: The Z-axis motor is fixedly connected to the inner side of the main frame through a Z-axis motor mounting plate, a partition is fixedly connected to the inner side of the main frame, a damper is arranged at a position corresponding to the partition and the Z-axis motor, and the spline shaft passes through the damper.

4. A multi-channel pipetting device according to claim 1, characterized in that: A wire pressing plate is fixedly connected to one side of the special-shaped rack close to the pipette, a pressing plate is fixedly connected to the side of the slide seat, and wire grooves are respectively fixedly connected to the two sides of the top of the main frame, and cables are movably connected in the wire grooves, one end of the cable is connected to the pipette, and the cable is fixed by the wire pressing plate and the pressing plate.

5. A multi-channel pipetting device according to claim 1, characterized in that: The linear motion module includes a Y-axis motor mounting plate, a plurality of Y-axis motors are fixedly connected to the side of the Y-axis motor mounting plate, an output shaft of the Y-axis motor is keyed to a driving wheel, a plurality of tensioning pulleys are rotatably connected to the inner side of the main frame, the driving wheel and the tensioning pulley are connected via a synchronous belt transmission, the synchronous belt is fixedly connected to a clamping block, and the clamping blocks correspond to and are fixedly connected to the slide seats one by one.

6. A multi-channel pipetting device according to claim 5, characterized in that: A plurality of second guide rails are fixedly connected to the inner side of the main frame, and a second slider is slidably connected to the second guide rail. The second slider corresponds to the slide seat one by one and is fixedly connected.

7. A multi-channel pipetting device according to claim 1, characterized in that: A plurality of the pipettes are arranged in a staggered manner.

8. A multi-channel pipetting device according to any one of claims 1 to 7, characterized in that: The number of the linear motion modules is four, the number of the slides is four, the number of the pipettes is four, and two of the linear motion modules, slides and pipettes are respectively arranged on both sides inside the main frame.

9. A multi-channel pipetting device according to any one of claims 1 to 7, characterized in that: The number of the linear motion modules is eight, the number of the slides is eight, the number of the pipettes is eight, and four linear motion modules, slides and pipettes are respectively arranged on both sides inside the main frame.

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