Cell transportation and storage box with temperature control regulation function

Abstract

The utility model discloses a cell transportation storage box with temperature control regulation, which comprises a box body with a box door, the box body comprises a partition plate, a semiconductor chilling plate, a mesh plate and a plurality of clamping mechanisms, the partition plate is fixed in the box body and divides the interior of the box body into a temperature control chamber and a heat exchange chamber, and the semiconductor chilling plate is fixed in the box body. The semiconductor refrigeration sheet is fixed in the partition plate, the refrigeration surface faces the temperature control chamber, the mesh plate is arranged in the temperature control chamber, the plurality of clamping mechanisms are arranged on the mesh plate at intervals, and test tubes for storing cells are clamped and placed on the clamping mechanisms. According to the utility model, the refrigeration surface of the semiconductor refrigeration sheet faces the temperature control chamber, so that a cell storage test tube placed in the temperature control chamber is adjusted to a proper temperature for storage, the test tube is clamped and fixed by arranging the spring and the rubber ring, and the bottom of the test tube is limited by arranging the sponge ring to be attached to the inner wall of the clamping ring; the clamping area of the test tube is reduced; meanwhile, the test tubes with different calibers are clamped.

Description

Technical Field

[0001] The utility model belongs to the technical field of cell transportation and storage, and particularly relates to a cell transportation and storage box with temperature control adjustment. Background Art

[0002] Cells are the basic structural and functional units of organisms. Cell storage is to preserve APSC pluripotent cells in cells for a certain period through a certain method to ensure that the functions and activities of the cells are not significantly affected. Cell storage is to preserve cells for a certain period through a certain method to ensure that the functions and activities of the cells are not significantly affected. It is a new concept first proposed in the Life Ark Project started by humans in the early 21st century.

[0003] In the prior art, cells sometimes need to be stored and transported after extraction. The Chinese patent document with the patent number 202220814606.9 discloses a stem cell storage and transportation box that is convenient for taking and placing. The device supports test tubes through clamping blocks and limit seats. The test tubes can complete support and shock absorption independently. Through the installation port, the material taking and placing components can be conveniently taken out. The ice bags are stored through a drawer, and the cold air circulates through a blower. The temperature inside the box is uniform. However, it cannot adjust the temperature inside the box during use. The most suitable storage temperatures for different cells vary.

[0004] Moreover, some of the existing cell transportation and storage boxes clamp the test tubes for storing cells through a sponge clamping mechanism with a cylindrical structure, which is not conducive to temperature adjustment. Therefore, improvement is needed. Summary of the Utility Model

[0005] The purpose of the utility model is to provide a cell transportation and storage box with temperature control adjustment, and the technical problems to be solved are: the temperature inside the storage box for storing cells cannot be adjusted, and the large-area airtight fitting and clamping of test tubes are not conducive to temperature adjustment.

[0006] To achieve the above purpose, the utility model provides the following technical solutions:

[0007] The utility model provides a cell transportation and storage box with temperature control adjustment, which includes a box body with a box door. The box body includes a partition board, a semiconductor refrigeration sheet, a mesh board and a plurality of clamping mechanisms. The partition board is fixed inside the box body to divide the inside of the box body into a temperature control chamber and a heat exchange chamber. The semiconductor refrigeration sheet is fixed in the partition board and the refrigerating surface faces the temperature control chamber. The mesh board is arranged inside the temperature control chamber. The plurality of clamping mechanisms are arranged on the mesh board at intervals. Test tubes for storing cells are clamped and placed on the clamping mechanisms.

[0008] By facing the cooling surface of the semiconductor refrigeration sheet towards the temperature control chamber, the temperature of the cell test tubes placed therein can be adjusted to a suitable temperature for storage. And by setting a mesh plate to clamp the test tubes, the influence of the overall large-area airtight clamping on the temperature adjustment of the test tubes can be avoided.

[0009] Optionally, fixed columns are fixed on both inner walls of the pair of temperature control chambers. The mesh plate is fixed in a storage plate with a rectangular frame structure. The pair of side edges of the storage plate are slidably clamped with the fixed columns, and a pull handle plate for easy pulling is arranged on the storage plate towards the box door.

[0010] Optionally, two chutes are symmetrically arranged along the length direction of each fixed column. Clamping blocks are arranged on the side surface of the storage plate and are slidably clamped in the chutes. A rotating shaft is rotatably connected in each fixed column. Both ends of the rotating shaft penetrate through the end parts of the fixed column. A grip wheel is arranged at the end of the rotating shaft close to the box door, and a limit locking hook is arranged at the end away from the box door. A locking ring adapted to the limit locking hook is arranged on the side edge of the storage plate away from the box door.

[0011] By arranging a pair of chutes up and down and corresponding clamping blocks for the chutes, the clamping connection of the storage plate is realized. By pulling the pull handle plate, the storage plate can slide along the chute, which is convenient for pulling out the storage plate to store the test tubes. And by setting the locking ring and the limit locking hook, the limit locking hook can be clamped into the locking ring by rotating the grip wheel, realizing the limit of the storage plate.

[0012] Optionally, each clamping mechanism includes a clamping ring, a sponge ring, a connecting column, several springs and a rubber ring. The clamping ring is fixed on the mesh plate. A sponge ring is arranged on the inner wall of the clamping ring. One ends of several springs are fixed on the clamping ring through the connecting column, and the other ends are connected with the rubber ring.

[0013] By arranging the springs and the rubber ring to clamp and fix the test tubes, and by arranging the sponge ring to be attached to the inner wall of the clamping ring to limit the bottom of the test tubes, the clamping area of the test tubes is reduced while realizing the clamping of test tubes with different diameters.

[0014] Optionally, the heating surface of the semiconductor refrigeration sheet faces the heat exchange chamber, and several wavy radiating fins are arranged at intervals on the heating surface of the semiconductor refrigeration sheet.

[0015] Optionally, louvers are arranged on both side surfaces of the heat exchange chamber. The openings of the louvers communicate with the spaced openings of several radiating fins, and a heat dissipation fan is further arranged on the inner wall of the heat exchange chamber.

[0016] By arranging the wavy radiating fins, it is convenient to collect the heat at the heating end face of the semiconductor refrigeration sheet. And by arranging the heat dissipation fan and the louvers, the heat dissipation at the heating end is realized.

[0017] Optionally, an electric heating tube for realizing rapid temperature rise adjustment is further arranged inside the temperature control chamber.

[0018] Advantages and benefits of the present utility model:

[0019] Compared with the prior art, the present utility model has the following beneficial effects:

[0020] 1. The cell transportation and storage box with temperature control regulation of the present utility model adjusts the refrigerating surface of the thermoelectric cooler towards the temperature control chamber, so as to adjust the temperature of the cell test tubes placed therein to a suitable temperature for storage. By using the thermoelectric cooler, the temperature can be quickly adjusted by adjusting the magnitude of the current, and by setting a mesh plate to clamp the test tubes, the influence of the overall large-area airtight clamping on the temperature regulation of the test tubes is avoided.

[0021] 2. The cell transportation and storage box with temperature control regulation of the present utility model realizes the snap connection of the storage board by arranging a pair of chutes up and down and corresponding clamping blocks for the chutes. By pulling the pulling plate by hand, the storage board can slide along the chute, which is convenient for pulling out the storage board to store the test tubes. And by setting a lock ring and a limit locking hook, the limit locking hook is clamped into the lock ring by rotating the grip wheel, so as to realize the limitation of the storage board.

[0022] 3. The cell transportation and storage box with temperature control regulation of the present utility model clamps and fixes the test tubes by setting springs and rubber rings, and realizes the limitation of the bottom of the test tubes by setting sponge rings attached to the inner wall of the clamping rings, reducing the clamping area of the test tubes while realizing the clamping of test tubes with different diameters. By setting wavy heat sinks, the heat of the heating end face of the thermoelectric cooler is collected, and by setting a heat dissipation fan and louvers, the heat dissipation of the heating end is realized. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 is a schematic structural diagram of the present utility model;

[0024] Figure 2 is a schematic front internal structure diagram of the present utility model;

[0025] Figure 3 is a schematic internal structure diagram of the present utility model;

[0026] Figure 4 is of the present utility model Figure 3 magnified structural diagram at A in;

[0027] Figure 5 is a schematic structural diagram related to the rotating shaft of the present utility model;

[0028] Figure 6 is a magnified structural diagram of the fixing column of the present utility model;

[0029] Figure 7 is a magnified schematic structural diagram of the clamping mechanism of the present utility model.

[0030] In the figure: 1 - box body, 2 - partition board, 3 - temperature control chamber, 4 - heat exchange chamber, 5 - semiconductor refrigeration sheet, 6 - heat sink, 7 - cooling fan, 8 - shutter, 9 - storage board, 10 - fixing column, 11 - sliding groove, 12 - rotating shaft, 13 - limit locking hook, 14 - grip wheel, 15 - mesh plate, 16 - locking ring, 17 - clamping block, 18 - clamping ring, 19 - sponge ring, 20 - connecting column, 21 - spring, 22 - rubber ring, 23 - electric heating tube, 24 - hand - pulling plate, 25 - box door. Specific implementation mode

[0031] The following further describes the present utility model in conjunction with the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the present utility model and cannot be used to limit the protection scope of the present utility model.

[0032] An embodiment is as Figures 1 to 7 shown, providing a cell transportation and storage box with temperature control adjustment, including a box body 1. Inside the box body 1, a partition board 2 is fixed to divide the inside of the box body 1 into upper and lower regions. The upper region is preferably a temperature control chamber 3, and the lower region is preferably a heat exchange chamber 4. In this embodiment, a semiconductor refrigeration sheet 5 in the prior art is embedded in the middle of the partition board 2. The refrigerating surface of the semiconductor refrigeration sheet 5 faces the temperature control chamber 3, and the heating surface faces the heat exchange chamber 4. In this embodiment, a plurality of clamping mechanisms are placed in the temperature control chamber 3, and test tubes for storing cells are clamped and placed in the clamping mechanisms.

[0033] During use, by adjusting the magnitude of the current through the semiconductor refrigeration sheet 5, rapid temperature adjustment can be achieved. By adjusting the temperature inside the temperature control chamber 3, it is convenient to adjust the storage and transportation temperatures of different cells in the test tubes. This adjustment method is common knowledge in the field of semiconductor refrigeration sheets 5, so it will not be elaborated here.

[0034] Refer to Figure 2 and Figure 3 shown. In this embodiment, a storage board 9 is connected inside the temperature control chamber 3 through fixing columns 10 fixed on a pair of side edges. The storage board 9 is preferably a rectangular frame structure. Inside the rectangular frame of the storage board 9, a mesh plate 15 is fixed. The mesh plate 15 is a metal or plastic mesh structure with a plurality of holes opened in the prior art. A number of clamping mechanisms are fixed on the mesh plate 15, and test tubes for storing cells are fixed in each clamping mechanism.

[0035] During use, the test tubes to be stored and transported are clamped and placed in the clamping mechanisms. The low temperature generated by the semiconductor refrigeration sheet 5 in the temperature control chamber 3 is convenient for storing cells, and the use of the mesh - structured mesh plate 15 reduces the temperature influence on the test tubes;

[0036] Refer to Figure 2As shown in the figure, in this embodiment, several electric heating tubes 23 in the prior art are fixed on the inner wall of the top of the box body 1. By changing the current flowing through the electric heating tubes 23 in the prior art, the working temperature is changed, so as to realize the rapid heating inside the temperature control chamber 3. And in this embodiment, the internal temperature of the temperature control chamber 3 is monitored in real time by using a temperature sensor in the prior art. The internal temperature of the temperature control chamber 3 is adjusted to the appropriate temperature for the cells in the current test tube for storage and transportation by the semiconductor refrigeration sheet 5 and the electric heating tubes 23.

[0037] Reference Figure 3 and Figure 7 As shown in the figure, in this embodiment, several clamping mechanisms are preferably adopted to facilitate the clamping and storage of multiple test tubes at the same time. And in this embodiment, each clamping mechanism includes a clamping ring 18 fixed on the mesh plate 15. The clamping ring 18 is preferably of a ring structure, and a sponge ring 19 is glued to its inner wall. In this embodiment, three connecting columns 20 are fixed upward on each clamping ring 18, and each connecting column 20 is connected with a spring 21. The end of each spring 21 is annularly connected to the bottom of a rubber ring 22.

[0038] During use, the test tubes to be stored are placed in the clamping mechanism. The bottom of each test tube is sleeved into the rubber ring 22 and then clamped by the sponge ring 19. By setting the telescopic spring 21 and the rubber ring 22, the clamping mechanism can be applicable to test tubes with different diameters and different lengths. By adopting the rubber ring 22 and the sponge ring 19, it is ensured that at least two horizontal planes of each test tube are annularly clamped, realizing clamping while reducing the contact area with the test tube, and reducing the temperature influence caused by excessive contact during clamping.

[0039] Reference Figure 3 、 Figure 4 、 Figure 5 and Figure 6 As shown in the figure, in this embodiment, a pair of fixed columns 10 located inside the temperature control chamber 3 are preferably provided, and are symmetrically fixed on the side walls of the temperature control chamber 3. In this embodiment, a pair of sliding grooves 11 are symmetrically opened along the length direction of the column body of each fixed column 10. A pair of clamping blocks 17 are fixed on each side of the storage plate 9 connected to the fixed column 10. Each pair of clamping blocks 17 are symmetrically clamped in the sliding grooves 11. And in this embodiment, a hand-pulling plate 24 is fixed on the side of the storage plate 9 corresponding to the proximity of the box door 25.

[0040] During use, when the operator needs to take and store test tubes on the mesh plate 15, by opening the box door 25 and pulling the hand-pulling plate 24 by hand, the clamping blocks 17 on both sides of the storage plate 9 slide along the sliding grooves 11 until they slide out of the temperature control chamber 3, and then the test tubes can be taken or stored.

[0041] In each fixing column 10 of this embodiment, a rotating shaft 12 is rotatably connected. The rotating shaft 12 can be rotatably connected through a bearing in the prior art. In this embodiment, both ends of the rotating shaft 12 penetrate through the end of the fixing column 10 to the outside. A grip wheel 14 is fixed at the end of each rotating shaft 12 close to the cabinet door 25. A threaded structure facilitating hand holding is axially provided on the grip wheel 14. A limit locking hook 13 is provided at the end of each rotating shaft 12 away from the cabinet door 25. The limit locking hook 13 is preferably symmetrically arranged as two 7-shaped structures. In this embodiment, a locking ring 16 is provided on the side of the storage plate 9 away from the cabinet door 25, and the locking ring 16 is located on the arc of the circular motion of the limit locking hook 13.

[0042] During use, after taking or storing a test tube and pushing the storage plate 9, when the clamping block 17 moves along the sliding groove 11 to the reset position, manually control the grip wheel 14 to drive the rotating shaft 12 to rotate until the limit locking hook 13 is clamped into the locking ring 16, so as to realize the limit fixation of the storage plate 9.

[0043] Reference Figure 2 As shown, in this embodiment, the heating surface of the semiconductor refrigeration sheet 5 faces the heat exchange chamber 4. A plurality of heat dissipation fins 6 are welded at intervals on the heating surface of the semiconductor refrigeration sheet 5 inside the heat exchange chamber 4. The heat dissipation fins 6 are preferably in a wavy structure. In this embodiment, louvers 8 in the prior art are provided on both sides of the heat exchange chamber 4, and the openings of the louvers 8 communicate with the spaced openings of the plurality of heat dissipation fins 6. A plurality of heat dissipation fans 7 are further provided on the inner wall of the heat exchange chamber 4, and the orientation of the heat dissipation fans 7 also communicates with the spaced openings of the plurality of heat dissipation fins 6.

[0044] During use, when the semiconductor refrigeration sheet 5 is in use, a large amount of heat is generated on its heating surface. The heat is collected by the heat dissipation fins 6 and then dissipated through the heat dissipation fans 7 and the louvers 8.

[0045] Working principle: When an operator needs to store cells in a test tube, open the cabinet door 25, control the hand pulling plate 24 to pull out the storage plate 9, insert the test tube into the clamping mechanism. Under the action of the sponge ring 19, the spring 21 and the rubber ring 22, test tubes with different calibers and lengths can be accommodated. After storage, push the storage plate 9 back to the original position, manually control the grip wheel 14 to rotate so that the limit locking hook 13 is clamped into the locking ring 16, completing the limit of the storage plate 9 to prevent displacement of the storage plate 9 caused by bumps. After closing the cabinet door 25, control the semiconductor refrigeration sheet 5 to adjust the temperature inside the temperature control chamber 3 to the appropriate temperature for the cells in the test tube. When it is necessary to quickly increase the temperature, rapid adjustment is achieved through the electric heating tube 23.

Claims

1. A cell transport storage box with temperature control, comprising a box body (1) with a box door (25), characterized in that: The box (1) comprises a partition (2), a semiconductor cooling sheet (5), a mesh plate (15) and a plurality of clamping mechanisms. The partition (2) is fixed inside the box (1) to divide the inside of the box (1) into a temperature control chamber (3) and a heat exchange chamber (4). The semiconductor cooling sheet (5) is fixed in the partition (2) with the cooling surface facing the temperature control chamber (3). The mesh plate (15) is arranged inside the temperature control chamber (3). A plurality of the clamping mechanisms are arranged at intervals on the mesh plate (15). Test tubes for storing cells are clamped and placed on the clamping mechanisms.

2. A cell transport storage box with temperature control according to claim 1, characterized in that: A pair of inner walls of the temperature control chamber (3) are both fixed with fixed columns (10), the mesh plate (15) is fixed in a storage plate (9) of a rectangular frame structure, a pair of side edges of the storage plate (9) are slidably engaged with the fixed columns (10), and a hand-pull plate (24) is provided on the storage plate (9) facing the box door (25) for easy pulling.

3. A cell transport storage box with temperature control according to claim 2, characterized in that: Each fixed column (10) is symmetrically provided with two slide grooves (11) along the length direction of the column body, and a clamping block (17) is provided on the side of the storage plate (9) and is slidably engaged in the slide groove (11). A rotating shaft (12) is rotatably connected in each of the fixed columns (10), and both ends of the rotating shaft (12) pass through the ends of the fixed columns (10), and a grip wheel (14) is provided at the end of the rotating shaft (12) close to the box door (25), and a limit lock hook (13) is provided at the end away from the box door (25). A lock ring (16) adapted to lock with the limit lock hook (13) is provided on the side of the storage plate (9) away from the box door (25).

4. A cell transport storage box with temperature control according to claim 3, characterized in that: Each clamping mechanism comprises a clamping ring (18), a sponge ring (19), a connecting column (20), a plurality of springs (21) and a rubber ring (22); the clamping ring (18) is fixed on the mesh plate (15); the inner wall of the clamping ring (18) is provided with a sponge ring (19); one end of the plurality of springs (21) is fixed to the clamping ring (18) through the connecting column (20), and the other end is connected to the rubber ring (22).

5. A cell transport storage box with temperature control according to claim 4, characterized in that: The heating surface of the semiconductor refrigeration sheet (5) faces the heat exchange chamber (4), and a plurality of wavy heat sinks (6) are arranged at intervals on the heating surface of the semiconductor refrigeration sheet (5).

6. A cell transport storage box with temperature control according to claim 5, characterized in that: Shutters (8) are provided on both sides of the heat exchange chamber (4), and the openings of the shutters (8) are in communication with the spaced openings of a plurality of heat sinks (6), and a heat dissipation fan (7) is also provided on the inner wall of the heat exchange chamber (4).

7. A cell transport storage box with temperature control according to claim 6, characterized in that: An electric heating tube (23) for achieving rapid temperature regulation is also provided inside the temperature control chamber (3).

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