2-chloronicotinonitrile enzyme hydrolysis reaction filtering kettle

Abstract

The utility model relates to the field of reaction filtering kettles, in particular to a 2-chloro-nicotinonitrile enzyme hydrolysis reaction filtering kettle which comprises a reaction tank, a movable cover plate is movably arranged at the upper end of the reaction tank, uniformly distributed screw holes are formed in the upper end of the movable cover plate in a penetrating manner, a needle cylinder is movably arranged in one screw hole, the needle cylinder is made of a transparent material, scales are arranged on the side wall of the needle cylinder, and a piston is movably arranged on the inner wall of the needle cylinder. The piston is manually pushed to inject quantitatively extracted raw material liquid in the needle cylinder into the reaction tank, then the brake assembly on the movable cover plate is started to enable the rotating column to rotate, then mixed liquid in the reaction tank can be stirred, and after sediment is generated, the electric cylinder is started to enable the output shaft of the electric cylinder to extend upwards, so that the reaction tank is sealed. When the fixing ring is lifted upwards, the reaction tank can be lifted upwards, then a solution flows into the collecting body through the filtering plate, and rapid solid-liquid separation is achieved through gravity.

Description

Technical Field

[0001] The utility model belongs to the field of reaction filtration kettles, and particularly relates to a 2-chloronicotinonitrile enzymatic hydrolysis reaction filtration kettle. Background Art

[0002] With the continuous development of the chemical industry, organic synthesis reactions play an important role in fields such as medicine, pesticides, and materials. In organic synthesis, enzymatic catalytic reactions have become a research hotspot due to their advantages such as high selectivity, high efficiency, and environmental friendliness. 2-chloronicotinonitrile is an important organic synthesis intermediate and is widely used in industries such as pesticides and medicine.

[0003] During the current 2-chloronicotinonitrile enzymatic hydrolysis reaction, first, raw materials such as the substrate, enzyme, and reaction buffer for the enzymatic catalytic reaction need to be mixed together. The products generated by the enzymatic hydrolysis reaction usually include liquid products in the solution and possible precipitates or solid particles. In order to separate and extract the target product, filters or filtration devices are usually used. However, when the enzymatic hydrolysis reaction filtration kettle in the prior art is used, it is not convenient to quickly and quantitatively put in the raw materials, and it is difficult to quickly filter the reaction mixture, and the target product in the solution cannot be quickly separated from the solid particles or precipitates.

[0004] Therefore, a 2-chloronicotinonitrile enzymatic hydrolysis reaction filtration kettle is proposed, which is convenient for quickly and quantitatively putting in the raw materials, can quickly filter the reaction mixture, and can quickly separate the target product in the solution from the solid particles or precipitates. Summary of the Utility Model

[0005] In order to overcome the problems that when the enzymatic hydrolysis reaction filtration kettle in the prior art is used, it is not convenient to quickly and quantitatively put in the raw materials, and it is difficult to quickly filter the reaction mixture, and the target product in the solution cannot be quickly separated from the solid particles or precipitates.

[0006] The technical solution of the utility model is as follows: A 2-chloronicotinonitrile enzymatic hydrolysis reaction filtration kettle includes a reaction tank; an activity cover plate is movably arranged at the upper end of the reaction tank, and uniformly distributed screw holes are penetrated through the upper end of the activity cover plate. A syringe is movably arranged inside one of the screw holes. The syringe is made of a transparent material and its side wall is provided with scales. A piston is movably arranged inside the inner wall of the syringe. A plug column is threadedly installed inside the inner wall of another screw hole. A rotating column is rotatably installed through the center of the upper end of the activity cover plate. A collector is movably arranged at the lower end of the reaction tank. Electric cylinders are fixedly connected to the four corners of the upper end of the collector. A fixed ring is fixedly connected to the upper part of the side wall of the reaction tank. Stirring plates are fixedly connected to the lower part of the side wall of the rotating column. A screw groove is penetrated through the lower end of the reaction tank. An installation disk is threadedly installed inside the inner wall of the screw groove. A cross groove is penetrated through the upper end of the installation disk. A filter plate is fixedly connected to the inner wall of the cross groove. A braking component is arranged on the activity cover plate, and a pressure filtration component is arranged on the rotating column.

[0007] Preferably, during use, first use a syringe to extract the reaction solution and know the volume of the extracted solution according to the scale on the side wall of the syringe. Then insert the output end of the syringe into the screw hole, manually push the piston to inject the quantitatively extracted raw material liquid in the syringe into the reaction tank. Then turn on the braking component on the movable cover plate to make the rotating column rotate, and the mixed liquid in the reaction tank can be stirred. After precipitation is formed, turn on the electric cylinder to make the output shaft of the electric cylinder extend upward. When the fixed ring is lifted upward, the reaction tank can be lifted upward. Then the solution will flow into the collector through the filter plate, realizing rapid solid-liquid separation, and solving the problems that in the prior art, it is inconvenient to quickly and quantitatively put raw materials during the use of the enzyme hydrolysis reaction filter kettle, and it is impossible to quickly separate the target product in the solution from solid particles or precipitates.

[0008] Preferably, the fixed ring is located above the electric cylinder, and the top view of the fixed ring covers the four electric cylinders at the same time. When the output shaft of the electric cylinder extends upward, the fixed ring can be jacked up, which is convenient for quickly adjusting the height of the reaction tank.

[0009] Preferably, the braking component includes an internally threaded cylinder, a toothed ring, a first motor and a gear; the upper part of the outer wall of the rotating column is threadedly installed with an internally threaded cylinder, the outer wall of the internally threaded cylinder is fixedly connected with a toothed ring, the upper end of the movable cover plate is fixedly connected with a first motor, the upper end of the output shaft of the first motor is fixedly connected with a gear, and the gear and the toothed ring are meshed with each other. Turn on the first motor to make the gear rotate, and the gear drives the toothed ring to rotate, thereby driving the rotating column to rotate, and rapid stirring of the mixed liquid in the reaction tank can be realized.

[0010] Preferably, a placement groove is opened at the upper end of the collector, the inner wall of the placement groove fits with the lower outer wall of the reaction tank, and a water outlet pipe is fixedly connected through the front end of the collector. A solenoid valve is fixedly arranged on the water outlet pipe, and the solution flows into the placement groove. Opening the solenoid valve can make the solution flow out from the water outlet pipe.

[0011] Preferably, the lower end of the movable cover plate is fixedly connected with a second limiting cylinder, and the outer wall of the second limiting cylinder fits with the upper part of the inner wall of the reaction tank. The setting of the second limiting cylinder facilitates the quick and stable placement of the movable cover plate on the upper end of the reaction tank.

[0012] Preferably, the filter press assembly includes a groove, a second motor, a screw rod, a threaded sleeve, a lifting plate, a stirring column, filter holes, and a first limiting cylinder; a groove is formed at the lower end of the rotating column, the top surface of the inner wall of the groove is fixedly connected with a second motor, the lower end of the output shaft of the second motor is fixedly connected with a screw rod, the outer wall of the screw rod is threadedly installed with a threaded sleeve, the outer wall of the threaded sleeve is fixedly connected with a lifting plate, the upper end edge of the lifting plate is fixedly connected with uniformly distributed stirring columns, filter holes are formed through the upper end of the lifting plate, the second motor is a forward and reverse motor, when the second motor is turned on to make the screw rod rotate forward or backward, the threaded sleeve will move upward or downward along the outer wall of the screw rod, and the height of the lifting plate can be quickly adjusted, and the filter press assembly can rotate with the rotation of the rotating column. When the filter press assembly rotates, the stirring columns can improve the stirring effect on the mixed liquid in the reaction tank. After the precipitate is formed, the lifting plate is moved downward to squeeze the precipitate downward, so that the solution in the precipitate can be quickly filtered, and the solution can quickly flow downward through the filter plate.

[0013] Preferably, a first limiting cylinder is fixedly connected to the center of the upper end of the mounting plate, the outer wall of the lower end of the screw rod fits with the inner wall of the first limiting cylinder, and the outer wall of the lower end of the screw rod will stably rotate along the inner wall of the first limiting cylinder. When the rotating column moves upward, the screw rod will move upward along the inner wall of the first limiting cylinder and be lifted out.

[0014] Advantages of the present utility model:

[0015] 1. Use a syringe to extract the reaction solution and obtain the volume of the extracted solution according to the scale on the side wall of the syringe. Then insert the output end of the syringe into the screw hole, manually push the piston to inject the quantitatively extracted raw material liquid in the syringe into the reaction tank. Then turn on the braking component on the movable cover plate to make the rotating column rotate, and the mixed liquid in the reaction tank can be stirred. After the precipitate is formed, turn on the electric cylinder to make the output shaft of the electric cylinder extend upward. When the fixed ring is lifted upward, the reaction tank can be lifted upward. Then the solution will flow into the collector through the filter plate, and solid-liquid rapid separation is achieved by gravity, solving the problems in the prior art that it is inconvenient to quickly and quantitatively put raw materials during the use of the enzyme hydrolysis reaction filter kettle, and it is impossible to quickly separate the target product in the solution from solid particles or precipitates.

[0016] 2. By starting the second motor to rotate the screw rod forward or backward, the threaded sleeve will move upward or downward along the outer wall of the screw rod, and the height of the lifting plate can be quickly adjusted. Moreover, the pressure filtration assembly can rotate with the rotation of the rotating column. When the pressure filtration assembly rotates, the stirring column can improve the stirring effect on the mixed liquid in the reaction tank. After the precipitation is formed, the lifting plate is moved downward to squeeze the precipitation downward, so that the solution in the precipitation can be quickly pressure-filtered, and the solution can quickly flow downward through the filter plate. By utilizing gravity and pressure, the speed of solid-liquid separation is increased, solving the problem that in the prior art, it is difficult to quickly filter the reaction mixture in the enzyme hydrolysis reaction filter kettle, and the target product in the solution cannot be quickly separated from the solid particles or precipitates;

[0017] 3. By starting the first motor to rotate the gear, the gear drives the toothed ring to rotate, thereby driving the rotating column to rotate, which can achieve rapid stirring of the mixed liquid in the reaction tank. The setting of the second limiting cylinder facilitates the quick and stable placement of the movable cover plate on the upper end of the reaction tank. By setting the first limiting cylinder, the lower outer wall of the screw rod will rotate stably along the inner wall of the first limiting cylinder. When the rotating column moves upward, the screw rod will move upward along the inner wall of the first limiting cylinder and be lifted out, which is convenient to use. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 Shown is a three-dimensional structural schematic diagram of a 2-chloronicotinonitrile enzyme hydrolysis reaction filter kettle of the present utility model;

[0019] Figure 2 Shown is a three-dimensional structural schematic diagram of a movable cover plate of a 2-chloronicotinonitrile enzyme hydrolysis reaction filter kettle of the present utility model;

[0020] Figure 3 Shown is a three-dimensional structural schematic diagram of a rotating column of a 2-chloronicotinonitrile enzyme hydrolysis reaction filter kettle of the present utility model;

[0021] Figure 4 Shown is a three-dimensional structural schematic diagram of an installation plate of a 2-chloronicotinonitrile enzyme hydrolysis reaction filter kettle of the present utility model;

[0022] Figure 5 Shown is a three-dimensional sectional structural schematic diagram of a pressure filtration assembly of a 2-chloronicotinonitrile enzyme hydrolysis reaction filter kettle of the present utility model.

[0023] The reference signs in the drawings are: 1, reaction tank; 2, movable cover plate; 201, internal threaded cylinder; 202, toothed ring; 203, first motor; 204, gear; 3, screw hole; 4, syringe; 5, piston; 6, plug column; 7, rotating column; 701, groove; 702, second motor; 703, screw rod; 704, threaded sleeve; 705, lifting plate; 706, stirring column; 707, filtering hole; 708, first limiting cylinder; 8, collector; 9, placement groove; 10, electric cylinder; 11, fixing ring; 12, water outlet pipe; 13, solenoid valve; 14, second limiting cylinder; 15, stirring plate; 16, screw groove; 17, mounting plate; 18, cross groove; 19, filter plate. Detailed implementation manners

[0024] The present utility model will be further described below in conjunction with the drawings and embodiments.

[0025] Embodiment 1

[0026] Please refer to Figures 1-5 A 2-chloronicotinonitrile enzymatic hydrolysis reaction filter kettle, comprising a reaction tank 1; a movable cover plate 2 is movably arranged at the upper end of the reaction tank 1, and uniformly distributed screw holes 3 are formed through the upper end of the movable cover plate 2. A syringe 4 is movably arranged inside one of the screw holes 3. The syringe 4 is made of a transparent material and its side wall is provided with scales. A piston 5 is movably arranged on the inner wall of the syringe 4. A plug column 6 is threadedly installed on the inner wall of another screw hole 3. A rotating column 7 is rotatably installed through the center of the upper end of the movable cover plate 2. A collector 8 is movably arranged at the lower end of the reaction tank 1. Electric cylinders 10 are fixedly connected to the four corners of the upper end of the collector 8. A fixing ring 11 is fixedly connected to the upper part of the side wall of the reaction tank 1. Stirring plates 15 are uniformly distributed and fixedly connected to the lower part of the side wall of the rotating column 7. A screw groove 16 is formed through the lower end of the reaction tank 1. A mounting plate 17 is threadedly installed on the inner wall of the screw groove 16. A cross groove 18 is formed through the upper end of the mounting plate 17. A filter plate 19 is fixedly connected to the inner wall of the cross groove 18. A braking assembly is arranged on the movable cover plate 2, and a pressure filtering assembly is arranged on the rotating column 7.

[0027] Please refer to Figure 1 In this embodiment, the fixing ring 11 is located above the electric cylinders 10, and the top view of the fixing ring 11 covers the four electric cylinders 10 at the same time.

[0028] Please refer to Figure 1 and 2 In this embodiment, the braking assembly includes an internal threaded cylinder 201, a toothed ring 202, a first motor 203 and a gear 204; the upper part of the outer wall of the rotating column 7 is threadedly installed with the internal threaded cylinder 201. A toothed ring 202 is fixedly connected to the outer wall of the internal threaded cylinder 201. A first motor 203 is fixedly connected to the upper end of the movable cover plate 2. A gear 204 is fixedly connected to the upper end of the output shaft of the first motor 203. The gear 204 and the toothed ring 202 are meshed with each other.

[0029] Please refer to Figure 1 and 2 In this embodiment, a placement groove 9 is provided at the upper end of the collector 8, and the inner wall of the placement groove 9 fits against the lower outer wall of the reaction tank 1. A water outlet pipe 12 is fixedly connected through the front end of the collector 8, and a solenoid valve 13 is fixedly arranged on the water outlet pipe 12.

[0030] Please refer to Figure 1 and 3 In this embodiment, a second limiting cylinder 14 is fixedly connected to the lower end of the movable cover plate 2, and the outer wall of the second limiting cylinder 14 fits against the upper part of the inner wall of the reaction tank 1.

[0031] In this embodiment: During use, first use the syringe 4 to extract the reaction solution and obtain the volume of the extracted solution according to the scale on the side wall of the syringe 4. Then insert the output end of the syringe 4 into the screw hole 3, and manually push the piston 5 to inject the quantitatively extracted raw material liquid in the syringe 4 into the reaction tank 1. Then start the first motor 203 to make the gear 204 rotate. The gear 204 drives the toothed ring 202 to rotate, thereby driving the rotating column 7 to rotate, and the mixed liquid in the reaction tank 1 can be stirred. After precipitation is formed, start the electric cylinder 10 to make the output shaft of the electric cylinder 10 extend upward. When the fixing ring 11 is lifted upward, the reaction tank 1 can be lifted upward. Then the solution will flow into the collector 8 through the filter plate 19 to achieve rapid solid-liquid separation. The solution flows into the placement groove 9, and opening the solenoid valve 13 can make the solution flow out from the water outlet pipe 12.

[0032] Embodiment 2

[0033] Please refer to Figure 5 On the basis of Embodiment 1, the present application provides a technical solution: The pressure filtration assembly includes a groove 701, a second motor 702, a screw rod 703, a threaded sleeve 704, a lifting disc 705, a stirring column 706, a filtering hole 707 and a first limiting cylinder 708; A groove 701 is provided at the lower end of the rotating column 7, the inner wall top surface of the groove 701 is fixedly connected with a second motor 702, the lower end of the output shaft of the second motor 702 is fixedly connected with a screw rod 703, a threaded sleeve 704 is threadedly installed on the outer wall of the screw rod 703, the outer wall of the threaded sleeve 704 is fixedly connected with a lifting disc 705, evenly distributed stirring columns 706 are fixedly connected to the upper edge of the lifting disc 705, a filtering hole 707 is penetrated and opened at the upper end of the lifting disc 705, a first limiting cylinder 708 is fixedly connected to the center of the upper end of the mounting disc 17, and the lower outer wall of the screw rod 703 fits against the inner wall of the first limiting cylinder 708.

[0034] In this embodiment: The second motor 702 is a reversible motor. When the second motor 702 is turned on to make the screw rod 703 rotate forward or backward, the threaded sleeve 704 will move upward or downward along the outer wall of the screw rod 703, and the height of the lifting disc 705 can be quickly adjusted. Moreover, the pressure filtration assembly can rotate with the rotation of the rotating column 7. When the pressure filtration assembly rotates, the stirring column 706 can improve the stirring effect on the mixed liquid in the reaction tank 1. After the precipitate is formed, the lifting disc 705 is moved downward to squeeze the precipitate downward, so that the rapid pressure filtration of the solution in the precipitate can be realized, and the solution quickly flows downward through the filter plate 19. The lower end outer wall of the screw rod 703 will rotate stably along the inner wall of the first limiting cylinder 708. When the rotating column 7 moves upward, the screw rod 703 will move upward along the inner wall of the first limiting cylinder 708 and be lifted out.

[0035] Working principle: First, use the syringe 4 to extract the reaction solution and obtain the volume of the extracted solution according to the scale on the side wall of the syringe 4. Then, insert the output end of the syringe 4 into the screw hole 3, and manually push the piston 5 to inject the quantitatively extracted raw material liquid in the syringe 4 into the reaction tank 1.

[0036] Then turn on the first motor 203 to make the gear 204 rotate. The gear 204 drives the toothed ring 202 to rotate, thereby driving the rotating column 7 to rotate, and the mixed liquid in the reaction tank 1 can be stirred. The pressure filtration assembly can rotate with the rotation of the rotating column 7. When the pressure filtration assembly rotates, the stirring column 706 can improve the stirring effect on the mixed liquid in the reaction tank 1. After the precipitate is formed, turn on the electric cylinder 10 to make the output shaft of the electric cylinder 10 extend upward. When the fixed ring 11 is lifted upward, the reaction tank 1 can be lifted upward. Then the solution will flow into the collector 8 through the filter plate 19 to achieve rapid solid-liquid separation. The solution flows into the placement groove 9, and by opening the solenoid valve 13, the solution can flow out from the water outlet pipe 12.

[0037] When it is necessary to improve the solid-liquid separation effect, since the second motor 702 is a reversible motor, turn on the second motor 702 to make the screw rod 703 rotate forward or backward. The threaded sleeve 704 will move upward or downward along the outer wall of the screw rod 703, and the height of the lifting disc 705 can be quickly adjusted. Moving the lifting disc 705 downward can squeeze the precipitate downward, so that the rapid pressure filtration of the solution in the precipitate can be realized, and the solution quickly flows downward through the filter plate 19. The solution flows into the placement groove 9, and by opening the solenoid valve 13, the solution can flow out from the water outlet pipe 12, which is convenient for collection.

[0038] The above describes the embodiments of the present invention in detail with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the purpose of the present invention.

Claims

1. A 2-chloronicotinonitrile enzymatic hydrolysis reaction filtration kettle, comprising a reaction tank (1); characterized in that: A movable cover plate (2) is movably provided at the upper end of the reaction tank (1), and screw holes (3) are evenly distributed through the upper end of the movable cover plate (2). A syringe (4) is movably provided inside one of the screw holes (3), and the syringe (4) is made of a transparent material and has a scale on its side wall. A piston (5) is movably provided on the inner wall of the syringe (4), and a plug column (6) is threadedly installed on the inner wall of the other screw hole (3). A rotating column (7) is rotatably installed through the center of the upper end of the movable cover plate (2), and a collecting body (8) is movably provided at the lower end of the reaction tank (1). The collecting body (8) ) are fixedly connected to the four corner edges of the upper end of the reaction tank (1), a fixing ring (11) is fixedly connected to the upper part of the side wall of the reaction tank (1), and a uniformly distributed stirring plate (15) is fixedly connected to the lower part of the side wall of the rotating column (7). A screw groove (16) is penetrated through the lower end of the reaction tank (1), and a mounting plate (17) is threadedly installed on the inner wall of the screw groove (16). A cross groove (18) is penetrated through the upper end of the mounting plate (17), and a filter plate (19) is fixedly connected to the inner wall of the cross groove (18). A brake assembly is arranged on the movable cover plate (2), and a filter press assembly is arranged on the rotating column (7).

2. A 2-chloronicotinonitrile enzymatic hydrolysis reaction filtration kettle according to claim 1, characterized in that: The fixing ring (11) is located above the electric cylinder (10), and the top surface of the fixing ring (11) covers the four electric cylinders (10) at the same time.

3. A 2-chloronicotinonitrile enzymatic hydrolysis reaction filtration kettle according to claim 1, characterized in that: The brake assembly comprises an internal threaded cylinder (201), a gear ring (202), a first motor (203) and a gear (204); the internal threaded cylinder (201) is threadedly mounted on the upper part of the outer wall of the rotating column (7), the gear ring (202) is fixedly connected to the outer wall of the internal threaded cylinder (201), the first motor (203) is fixedly connected to the upper end of the movable cover plate (2), the gear (204) is fixedly connected to the upper end of the output shaft of the first motor (203), and the gear (204) and the gear ring (202) are meshed with each other.

4. A 2-chloronicotinonitrile enzymatic hydrolysis reaction filtration kettle according to claim 1, characterized in that: A placement groove (9) is provided at the upper end of the collecting body (8), the inner wall of the placement groove (9) is in contact with the outer wall of the lower end of the reaction tank (1), and a water outlet pipe (12) is fixedly connected to the front end of the collecting body (8), and a solenoid valve (13) is fixedly provided on the water outlet pipe (12).

5. A 2-chloronicotinonitrile enzymatic hydrolysis reaction filtration kettle according to claim 1, characterized in that: The lower end of the movable cover plate (2) is fixedly connected to a second limiting cylinder (14), and the outer wall of the second limiting cylinder (14) is in contact with the upper part of the inner wall of the reaction tank (1).

6. A 2-chloronicotinonitrile enzymatic hydrolysis reaction filtration kettle according to claim 1, characterized in that: The filter press assembly comprises a groove (701), a second motor (702), a screw (703), a threaded sleeve (704), a lifting plate (705), a stirring column (706), a filter hole (707) and a first limiting cylinder (708); a groove (701) is provided at the lower end of the rotating column (7), the second motor (702) is fixedly connected to the top surface of the inner wall of the groove (701), the lower end of the output shaft of the second motor (702) is fixedly connected to the screw (703), the outer wall of the screw (703) is threadedly mounted with a threaded sleeve (704), the outer wall of the threaded sleeve (704) is fixedly connected to the lifting plate (705), the upper edge of the lifting plate (705) is fixedly connected with evenly distributed stirring columns (706), and the upper end of the lifting plate (705) is penetrated by a filter hole (707).

7. A 2-chloronicotinonitrile enzymatic hydrolysis reaction filtration kettle according to claim 6, characterized in that: A first limiting cylinder (708) is fixedly connected to the center of the upper end of the mounting plate (17), and the outer wall of the lower end of the screw rod (703) is in contact with the inner wall of the first limiting cylinder (708).

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