Cell culture device for medical research
By designing a cell culture device with a rotating structure, the problem of easy destruction of the sterile environment during the cell culture process is solved, and the operation of dropping the culture medium without opening the incubator is realized, which improves the success rate of cell culture.
Patent Information
- Application Number
- CN202420465235.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-03-11
- Publication Date
- 2025-05-30
- Estimated Expiration
- 2034-03-11
AI Technical Summary
During the cell culture process, when dropping the culture medium, you need to open the incubator, which can easily destroy the sterile environment and lead to cell culture failure.
A cell culture device including a circular shaft, a rotary structure, a dropper structure and an incubator structure is designed. The rotary structure drives the rotation of the dropper and the incubator, so that the culture medium can be dripped without opening the incubator.
This device allows the operator to view the culture of multiple cells without moving, and by controlling the distance of the dropper drops, the cells can be dripped into the culture medium without contacting large areas of air, thereby improving the success rate of cell culture.
Smart Images
Figure CN222923153U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of cell culture devices, in particular to a cell culture device for medical research. Background Technique
[0002] Cell culture is a technique for culturing and propagating cells in a laboratory, and this technique is commonly used in fields such as biomedical research, drug screening, and biopharmaceuticals; usually, cell culture needs to be carried out in a sterile environment. However, during the culturing process, culture medium needs to be dripped for subsequent cell culture work. However, when dripping the culture medium, the incubator needs to be opened, and this process easily destroys the sterile environment, resulting in the failure of cell culture. Moreover, cells need to be cultured independently to increase the possibility of success. Therefore, those skilled in the art have provided a cell culture device for medical research to solve the problems raised in the above background technique. Content of the Utility Model
[0003] The purpose of the utility model is to provide a cell culture device for medical research to solve the problems raised in the above background technique.
[0004] To achieve the above purpose, the utility model provides the following technical solution:
[0005] A cell culture device for medical research includes a round shaft, a rotating structure, a dropper structure, and an incubator structure; the lower end of the round shaft is fixedly connected to a bottom plate, and a rotating structure is arranged on the upper end of the bottom plate and on the shaft arm of the round shaft. Four equally spaced dropper structures are arranged on the rotating structure, and incubator structures are arranged at the lower ends of both the rotating structure and the dropper structure; the rotating structure includes a rotating connection plate, grooves, a rotating shaft, round holes, connecting slide bars, and first chutes. A rotating shaft is arranged on the rotating structure, and a rotating connection plate is fixedly connected to the upper side of the shaft arm of the rotating shaft. Grooves are opened at the front, rear, left, and right four ports of the rotating connection plate. Round holes are opened at one end of the inner side of the groove and on the upper surface of the rotating connection plate, and the lower ends of the round holes all penetrate through the lower surface of the rotating connection plate. Connecting slide bars corresponding to the first chutes are fixedly connected to the lower ends of the four protruding positions of the rotating connection plate, and the connecting slide bars are all slidably connected to the first chutes; the dropper structure includes a tube cap, connecting threads, and a dropper. A dropper is arranged on the dropper structure, connecting threads are arranged on the tube arm of the dropper, and a tube cap is arranged on the connecting threads and is threadedly connected to the connecting threads.
[0006] Preferably, the incubator structure includes an incubator, a second chute, a first transparent window, a left sliding plate, a second transparent window, a buckle, a buckle groove, a pull plate, and a right sliding plate. An incubator is provided on the incubator structure. Second chutes are respectively provided on the left and right surfaces at the rear end of the incubator. First transparent windows are provided at both the left and right ends of the incubator. A left sliding plate is slidably connected to the left side of the front end inside the incubator, and a right sliding plate is slidably connected to the right side of the front end inside the incubator. Pull plates are respectively provided on the left side of the front end of the left sliding plate and the right side of the front end of the right sliding plate. Second transparent windows are provided at the front ends of the left sliding plate and the right sliding plate. Buckle grooves corresponding to the buckles are respectively provided on the upper and lower surfaces of the left end of the right sliding plate, and the buckle grooves are buckled and connected with the buckles; The rotating connecting plate on the rotating structure is fixedly connected to the dropper on the dropper structure. A through hole corresponding to the dropper is provided on the upper surface of the incubator on the incubator structure, and the lower end of the through hole penetrates through the inside of the incubator and is slidably connected to the dropper. A culture dish is provided at the lower end inside the incubator; A round shaft is movably connected to the inner side of the shaft arm of the rotating shaft on the rotating structure. A top plate is provided at the upper end of the round shaft. Support feet are provided at both the left and right ends of the bottom plate. Four sets of sliding frames corresponding to the second chutes on the incubator structure are provided on the lower side of the shaft arm of the rotating shaft and the lower end of the rotating connecting plate, and the sliding frames are slidably connected to the second chutes.
[0007] Compared with the prior art, the beneficial effects of the present utility model are as follows:
[0008] 1. Under the active action of the rotating shaft and the round shaft and the sliding action of the connecting sliding rod and the first chute, pull the connecting sliding rod to rotate, so that the connecting sliding rod drives the rotating connecting plate to rotate. The rotation of the rotating connecting plate drives the rotation of the rotating shaft, and the rotation of the rotating shaft drives the rotation of the sliding frame. While the sliding frame and the rotating connecting plate rotate, they also drive the rotation of the dropper structure and the incubator structure, thereby driving the rotation of the culture dish. This operation is beneficial for the operator to view the culture conditions of multiple cells without moving.
[0009] 2. When it is necessary to drip the culture medium in front of the cells to be dropped, under the sliding action of the sliding frame and the second chute, the dripping distance of the dropper can be controlled. Rotate the corresponding tube cap to separate the tube cap from the dropper, and then drip the culture medium from the dropper. The culture medium will flow along the dropper into the incubator and then into the culture dish. This operation is beneficial for dripping the culture medium into the cells without contacting a large area of air, improving the success rate of cell culture; Pull the pull plate, and the pulling of the pull plate drives the separation of the left sliding plate and the right sliding plate, so as to take out the culture dish and clean the incubator. Description of the Drawings
[0010] Figure 1 It is a schematic structural diagram of a cell culture device for medical research.
[0011] Figure 2It is a schematic diagram of the rotating structure of a cell culture device for medical research.
[0012] Figure 3 It is a schematic diagram of the dropper structure of a cell culture device for medical research.
[0013] Figure 4 It is a schematic diagram of the incubator structure of a cell culture device for medical research.
[0014] Figure 5 It is a schematic diagram of the left slide plate and the right slide plate of a cell culture device for medical research
[0015] In the figure: 1 - bottom plate, 2 - support foot pad, 3 - top plate, 4 - round shaft, 5 - carriage, 6 - rotating structure, 61 - rotating connection plate, 62 - groove, 63 - rotating shaft, 64 - round hole, 65 - connecting slide bar, 66 - first chute, 7 - dropper structure, 71 - tube cap, 72 - connecting thread, 73 - dropper, 8 - incubator structure, 81 - incubator, 82 - second chute, 83 - first transparent window, 84 - left slide plate, 85 - second transparent window, 86 - buckle, 87 - buckle groove, 88 - pull plate, 89 - right slide plate, 9 - culture dish, 10 - through hole. Detailed implementation manners
[0016] In order to make the technical means, creative features, achieved purposes and functions of the present utility model easy to understand, the present utility model will be further described below in conjunction with specific implementation manners. In the description of the present utility model, it should be noted that the orientation or positional relationship indicated by the terms "upper", "lower", "inner", "outer", "front end", "rear end", "both ends", "one end", "the other end", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present utility model. In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance. In the description of the present utility model, it should be noted that unless otherwise clearly specified and limited, the terms "installed", "provided with", "connected", etc. should be understood in a broad sense. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the internal communication of two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific situations.
[0017] Please refer to Figures 1 to 5, in the embodiment of the present utility model, a cell culture device for medical research includes a round shaft 4, a rotating structure 6, a dropper structure 7 and an incubator structure 8; the lower end of the round shaft 4 is fixedly connected to a bottom plate 1, and a rotating structure 6 is arranged on the upper end of the bottom plate 1 and on the shaft arm of the round shaft 4. Four equally spaced dropper structures 7 are arranged on the rotating structure 6, and incubator structures 8 are arranged on both the rotating structure 6 and the lower end of the dropper structure 7; the rotating structure 6 includes a rotating connecting plate 61, a groove 62, a rotating shaft 63, a round hole 64, a connecting slide bar 65 and a first chute 66. A rotating shaft 63 is arranged on the rotating structure 6, and a rotating connecting plate 61 is fixedly connected to the upper side of the shaft arm of the rotating shaft 63. Grooves 62 are opened at the front, rear, left and right four ports of the rotating connecting plate 61. Round holes 64 are opened at one end of the inner side of the groove 62 and on the upper surface of the rotating connecting plate 61, and the lower ends of the round holes 64 all penetrate through the lower surface of the rotating connecting plate 61. Connecting slide bars 65 corresponding to the first chute 66 are fixedly connected to the lower ends of the four protruding positions of the rotating connecting plate 61, and the connecting slide bars 65 are all slidably connected to the first chute 66; the dropper structure 7 includes a tube cap 71, a connecting thread 72 and a dropper 73. A dropper 73 is arranged on the dropper structure 7, a connecting thread 72 is arranged on the tube arm of the dropper 73, and a tube cap 71 is arranged on the connecting thread 72, and the tube cap 71 is threadedly connected to the connecting thread 72; the incubator structure 8 includes an incubator 81, a second chute 82, a first transparent window 83, a left slide plate 84, a second transparent window 85, a buckle 86, a buckle groove 87, a pull plate 88 and a right slide plate 89. An incubator 81 is arranged on the incubator structure 8. Second chutes 82 are opened on the left and right sides of the rear end surface of the incubator 81. First transparent windows 83 are arranged at both the left and right ends of the incubator 81. A left slide plate 84 is slidably connected to the left side of the front end inside the incubator 81, and a right slide plate 89 is slidably connected to the right side of the front end inside the incubator 81. Pull plates 88 are arranged on the left side of the front end of the left slide plate 84 and on the right side of the front end of the right slide plate 89. Second transparent windows 85 are arranged at the front ends of the left slide plate 84 and the right slide plate 89. Buckle grooves 87 corresponding to the buckle 86 are opened on the upper and lower sides of the left end surface of the right slide plate 89, and the buckle grooves 87 are buckled to the buckle 86; the rotating connecting plate 61 on the rotating structure 6 is fixedly connected to the dropper 73 on the dropper structure 7. A through hole 10 corresponding to the dropper 73 is opened on the upper surface of the incubator 81 on the incubator structure 8, and the lower end of the through hole 10 penetrates through the inside of the incubator 81 and is slidably connected to the dropper 73. A culture dish 9 is arranged at the lower end inside the incubator 81; the inner side of the shaft arm of the rotating shaft 63 on the rotating structure 6 is movably connected to the round shaft 4. A top plate 3 is arranged at the upper end of the round shaft 4. Support feet 2 are arranged at both the left and right ends of the bottom plate 1. Four groups of slide frames 5 corresponding to the second chutes 82 on the incubator structure 8 are arranged on the lower side of the shaft arm of the rotating shaft 63 and at the lower end of the rotating connecting plate 61, and the slide frames 5 are slidably connected to the second chutes 82.
[0018] The working principle of the present utility model is as follows: Under the active action between the rotating shaft 63 and the circular shaft 4 and the sliding action between the connecting slide bar 65 and the first sliding groove 66, the connecting slide bar 65 is pulled to rotate, causing the connecting slide bar 65 to drive the rotating connecting plate 61 to rotate. The rotation of the rotating connecting plate 61 drives the rotation of the rotating shaft 63, and the rotation of the rotating shaft 63 drives the rotation of the carriage 5. While the carriage 5 and the rotating connecting plate 61 are rotating, they also drive the rotation of the dropper structure 7 and the incubator structure 8, thereby driving the rotation of the culture dish 9. This operation is beneficial for the operator to view the culture conditions of multiple cells without moving. When it comes to the cell in front of which the culture medium needs to be dropped, under the sliding action between the carriage 5 and the second sliding groove 82, the dropping distance of the dropper 73 can be controlled. Rotate the corresponding tube cap 71 to separate the tube cap 71 from the dropper 73, and then drop the culture medium from the dropper 73. The culture medium will flow along the dropper 73 into the incubator 81 and then into the culture dish 9. This operation is beneficial for dropping the culture medium into the cell without the cell contacting a large area of air, improving the success rate of cell culture. Pull the pull plate 88, and the pulling of the pull plate 88 drives the separation of the left slide plate 84 and the right slide plate 89, so as to take out the culture dish 9 and clean the incubator 81.
[0019] For those skilled in the art, it is obvious that the present utility model is not limited to the details of the above-mentioned exemplary embodiments, and can be implemented in other specific forms without departing from the spirit or basic characteristics of the present utility model. Therefore, from any point of view, the embodiments should be regarded as exemplary and non-restrictive. The scope of the present utility model is defined by the appended claims rather than the above description. Therefore, all changes falling within the meaning and scope of the equivalent elements of the claims are intended to be included in the present utility model. Any reference signs in the claims should not be regarded as limiting the claims involved.
[0020] In addition, it should be understood that although this specification is described according to the embodiments, not every embodiment only contains an independent technical solution. This narrative way of the specification is only for clarity. Those skilled in the art should regard the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.
Claims
1. A cell culture device for medical research, comprising a circular shaft (4), a rotating structure (6), a dropper structure (7) and a culture box structure (8); characterized in that: The lower end of the circular shaft (4) is fixedly connected to a bottom plate (1); a rotating structure (6) is arranged on the upper end of the bottom plate (1) and the shaft arm of the circular shaft (4); four dropper structures (7) arranged at equal intervals are arranged on the rotating structure (6); and an incubator structure (8) is arranged on the rotating structure (6) and at the lower end of the dropper structure (7).
2. A cell culture device for medical research according to claim 1, characterized in that: The rotating structure (6) comprises a rotating connecting plate (61), a groove (62), a rotating shaft (63), a circular hole (64), a connecting sliding rod (65) and a first sliding groove (66); the rotating structure (6) is provided with a rotating shaft (63); the upper side of the shaft arm of the rotating shaft (63) is fixedly connected with the rotating connecting plate (61); the front, rear, left and right four ports of the rotating connecting plate (61) are all provided with grooves (62).
3. A cell culture device for medical research according to claim 1, characterized in that: The dropper structure (7) comprises a pipe cover (71), a connecting thread (72) and a dropper (73); the dropper (73) is arranged on the dropper structure (7); a connecting thread (72) is arranged on the upper side of a pipe arm of the dropper (73); a pipe cover (71) is arranged on the connecting thread (72); and the pipe cover (71) is threadedly connected to the connecting thread (72).
4. A cell culture device for medical research according to claim 1, characterized in that: The incubator structure (8) comprises an incubator (81), a second slide groove (82), a first transparent window (83), a left slide plate (84), a second transparent window (85), a buckle (86), a buckle groove (87), a pull plate (88) and a right slide plate (89). The incubator structure (8) is provided with an incubator (81), and second slide grooves (82) are provided on the surfaces of the left and right sides of the rear end of the incubator (81).
5. The cell culture device for medical research according to claim 1, characterized in that: The rotating connecting plate (61) on the rotating structure (6) is fixedly connected to the dropper (73) on the dropper structure (7); a through hole (10) corresponding to the dropper (73) is provided on the upper end surface of the incubator (81) on the incubator structure (8); the lower end of the through hole (10) passes through the interior of the incubator (81) and is slidably connected to the dropper (73); and a culture dish (9) is provided at the lower end of the interior of the incubator (81).
6. A cell culture device for medical research according to claim 1, characterized in that: The inner side of the shaft arm of the rotating shaft (63) on the rotating structure (6) is movably connected with a circular shaft (4), the upper end of the circular shaft (4) is provided with a top plate (3), the left and right ends of the bottom plate (1) are provided with supporting foot pads (2), and the lower side of the shaft arm of the rotating shaft (63) and the lower end of the rotating connecting plate (61) are provided with four groups of slides (5) corresponding to the second slide grooves (82) on the incubator structure (8), and the slides (5) are slidably connected with the second slide grooves (82).
7. A cell culture device for medical research according to claim 2, characterized in that: A circular hole (64) is provided at one inner end of the groove (62) and the upper end surface of the rotating connecting plate (61), and the lower end of the circular hole (64) passes through the lower end surface of the rotating connecting plate (61). The lower ends of the four protruding positions of the rotating connecting plate (61) are fixedly connected with connecting slide bars (65) arranged corresponding to the first sliding groove (66), and the connecting slide bars (65) are slidably connected to the first sliding groove (66).
8. The cell culture device for medical research according to claim 4, characterized in that: The incubator (81) is provided with a first transparent window (83) at both the left and right ends; a left slide plate (84) is slidably connected to the left side of the inner front end of the incubator (81); a right slide plate (89) is slidably connected to the right side of the inner front end of the incubator (81); and a pull plate (88) is provided at the left side of the front end of the left slide plate (84) and the right side of the front end of the right slide plate (89).
9. The cell culture device for medical research according to claim 4, characterized in that: The front ends of the left slide plate (84) and the right slide plate (89) are both provided with a second transparent window (85), and the surfaces of the upper and lower sides of the left end of the right slide plate (89) are both provided with a buckle groove (87) corresponding to the buckle (86), and the buckle groove (87) is buckled and connected with the buckle (86).