Sample injection auxiliary device of liquid chromatograph-mass spectrometer

By designing the injection auxiliary device of the liquid-mass junction device, automatic injection is achieved using sample turntables, motors, slots, cannulas and cylinders, the problem of inconvenient injection operation in the prior art is solved and the injection efficiency is improved.

CN222926684UActive Publication Date: 2025-05-30SHANGHAI XIHUA PHARMATECH CO LTD
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Patent Information

Application Number
CN202421842336.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-01
Publication Date
2025-05-30
Estimated Expiration
2034-08-01

AI Technical Summary

Technical Problem

The existing liquid-mass junction instrument sampling device requires manual insertion into the pipeline, which is not convenient enough to operate.

Method used

A sample injection auxiliary device for liquid-mass CTUA is designed, including a sample turntable, a motor, a slot, a cannula and a cylinder. The sample turntable and motor drives the rotation and replacement of the sample test tube, and combines the actions of the cylinder and a cannula to achieve automatic injection.

Benefits of technology

Through this device, the injection operation of the liquid-mass combo device is more convenient and quick, reducing the need for manual operation and improving work efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of liquid chromatography-mass spectrometer auxiliary devices, in particular to a sample introduction auxiliary device of a liquid chromatography-mass spectrometer, which comprises a bedplate, supporting legs are arranged at corners of the bottom of the bedplate, a sample rotary table is mounted at the top of the bedplate, slots are uniformly formed in the top surface of the sample rotary table, and the sample rotary table is mounted on the bedplate. A bottom plate is arranged on the rear side of the top surface of the table plate, stand columns are arranged on the top surface of the bottom plate in a bilateral symmetry mode, a threaded rod is installed in the middle of the top surface of the bottom plate, a top plate is arranged at the tops of the stand columns and the threaded rod, and a first motor is installed in the middle of the top of the top plate; according to the liquid chromatograph-mass spectrometer, sample test tubes can be driven to rotate and replace through the sample rotary table and the second motor, insertion tubes can be conveniently inserted into different sample test tubes through the bottom plate, the stand column, the threaded rod, the top plate, the first motor, the lifting plate, the air cylinder and the connecting plate, and in conclusion, sample injection of the liquid chromatograph-mass spectrometer can be more convenient.
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Description

Technical Field

[0001] The utility model relates to the technical field of auxiliary devices for liquid chromatography-mass spectrometry (LC-MS) instruments, and specifically relates to a sample injection auxiliary device for an LC-MS instrument. Background Art

[0002] LC-MS instruments are mainly applied to drug metabolism and pharmacokinetics research, clinical pharmacology research, development research of natural drugs (such as Chinese herbal medicines), neonatal screening, identification of proteins and peptides, residue analysis, toxicant analysis, environmental analysis - in industries such as public security, environmental protection, food, tap water, and health and epidemic prevention.

[0003] During the use of current sample injection devices of LC-MS instruments, it is necessary to manually insert the pipeline into the test tube for sample injection operation, making the sample injection operation of the LC-MS instrument inconvenient.

[0004] Therefore, an injection auxiliary device for an LC-MS instrument is needed to improve the above problems. Content of the Utility Model

[0005] The purpose of the utility model is to provide an injection auxiliary device for an LC-MS instrument to solve the problems raised in the above background art.

[0006] To achieve the above purpose, the utility model provides the following technical solution:

[0007] An injection auxiliary device for an LC-MS instrument, including a table board, support legs are arranged at the bottom corners of the table board, a sample turntable is installed on the top of the table board, slots are evenly opened on the top surface of the sample turntable, sample test tubes are placed inside the slots, a bottom board is arranged at the rear side of the top surface of the table board, columns are symmetrically arranged on the left and right of the top surface of the bottom board, a threaded rod is installed in the middle of the top surface of the bottom board, the top of the columns and the threaded rod is provided with a top board, a first motor is installed in the middle of the top of the top board, a lifting plate is sleeved on the outer walls of the columns and the threaded rod, a cylinder is installed in the middle of the top of the lifting plate, a connecting plate is arranged at the lower driving shaft of the cylinder, an inserting tube is fixedly sleeved on the front side of the connecting plate, an external hose is arranged at the top of the inserting tube, and a second motor is installed at the bottom of the table board corresponding to the sample turntable.

[0008] As a preferred scheme of the utility model, the connection mode between the sample turntable and the table board is a rotational connection.

[0009] As a preferred scheme of the utility model, the upper and lower ends of the threaded rod are respectively rotationally connected to the top board and the bottom board.

[0010] As a preferred scheme of the utility model, the connection mode between the lifting plate and the column is a sliding connection, and the connection mode between the lifting plate and the threaded rod is a threaded connection.

[0011] As a preferred solution of the present utility model, the external hose penetrates through the lifting plate, and the connection mode between the external hose and the lifting plate is a sliding connection.

[0012] As a preferred solution of the present utility model, the outer end of the external hose is correspondingly connected to the liquid chromatography-mass spectrometry instrument.

[0013] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0014] 1. In the present utility model, the sample turntable and the second motor are provided to drive the sample test tube to rotate and replace. The bottom plate, the column, the threaded rod, the top plate, the first motor, the lifting plate, the cylinder, and the connecting plate are provided to facilitate the insertion of the cannula into different sample test tubes. In summary, the above design can make the sample injection of the liquid chromatography-mass spectrometry instrument more convenient. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 is a schematic diagram of the overall structure of the present utility model;

[0016] Figure 2 is a schematic diagram of the sample turntable structure of the present utility model;

[0017] Figure 3 is a schematic diagram of a partial structure of the present utility model.

[0018] In the figure: 1, table board; 2, support leg; 3, sample turntable; 4, slot; 5, sample test tube; 6, bottom plate; 7, column; 8, threaded rod; 9, top plate; 10, first motor; 11, lifting plate; 12, cylinder; 13, connecting plate; 14, cannula; 15, external hose; 16, second motor. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0019] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments in the present utility model, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present utility model.

[0020] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments in the present utility model, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the present utility model.

[0021] To facilitate the understanding of the present utility model, the present utility model will be described more comprehensively below with reference to the relevant drawings. Several embodiments of the present utility model are given. However, the present utility model can be implemented in many different forms and is not limited to the embodiments described herein. On the contrary, these embodiments are provided to make the disclosure of the present utility model more thorough and comprehensive.

[0022] It should be noted that when an element is referred to as being "fixedly provided on" another element, it can be directly on the other element or there may also be an intermediate element. When an element is considered to be "connected" to another element, it can be directly connected to the other element or there may be an intermediate element at the same time. The terms "vertical", "horizontal", "left", "right" and similar expressions used herein are only for the purpose of illustration.

[0023] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the technical field to which the present utility model belongs. The terms used in the description of the present utility model herein are only for the purpose of describing specific embodiments and are not intended to limit the present utility model. The term "and / or" used herein includes any and all combinations of one or more of the related listed items.

[0024] For the embodiments, please refer to Figures 1-3 , the present utility model provides a technical solution:

[0025] An injection auxiliary device for a liquid chromatography-mass spectrometry instrument, comprising a table board 1, support legs 2 are arranged at the bottom corners of the table board 1, a sample turntable 3 is installed on the top of the table board 1, slots 4 are evenly opened on the top surface of the sample turntable 3, sample test tubes 5 are placed inside the slots 4, a bottom board 6 is arranged at the rear side of the top surface of the table board 1, columns 7 are symmetrically arranged on the left and right of the top surface of the bottom board 6, a threaded rod 8 is installed in the middle of the top surface of the bottom board 6, a top board 9 is arranged at the top of the columns 7 and the threaded rod 8, a first motor 10 is installed in the middle of the top of the top board 9, a lifting plate 11 is sleeved on the outer walls of the columns 7 and the threaded rod 8, a cylinder 12 is installed in the middle of the top of the lifting plate 11, a connecting plate 13 is arranged on the lower driving shaft of the cylinder 12, an insertion tube 14 is fixedly sleeved on the front side of the connecting plate 13, an external hose 15 is arranged at the top of the insertion tube 14, and a second motor 16 is installed at the bottom of the table board 1 and corresponding to the sample turntable 3.

[0026] In this embodiment, the sample turntable 3 is rotatably connected to the platen 1. The upper and lower ends of the threaded rod 8 are respectively rotatably connected to the top plate 9 and the bottom plate 6. The lifting plate 11 is slidably connected to the column 7. The lifting plate 11 is threadedly connected to the threaded rod 8. The external hose 15 passes through the lifting plate 11, and the external hose 15 is slidably connected to the lifting plate 11. The outer end of the external hose 15 is correspondingly connected to the liquid chromatography-mass spectrometry instrument. By providing the sample turntable 3 and the second motor 16, the sample test tube 5 can be rotated and replaced. The provided bottom plate 6, column 7, threaded rod 8, top plate 9, first motor 10, lifting plate 11, cylinder 12, and connecting plate 13 can facilitate the insertion of the cannula 14 into different sample test tubes 5. Through the above design, the sample injection of the liquid chromatography-mass spectrometry instrument can be made more convenient.

[0027] The working process of the present utility model is as follows: First, connect the external hose 15 to the liquid chromatography-mass spectrometry instrument. Then, insert multiple sample test tubes 5 into the slots 4. Next, start the first motor 10 to drive the threaded rod 8 to rotate. At this time, the lifting plate 11 moves to adjust the height. Then, start the cylinder 12 to push the cannula 14 into one of the sample test tubes 5. Then, start the liquid chromatography-mass spectrometry instrument to extract the liquid in the sample test tube 5. When it is necessary to extract the liquid in the next sample test tube 5, start the cylinder 12 to pull out the cannula 14 from the sample test tube 5. Then, start the second motor 16 to drive the sample turntable 3 to rotate. At this time, the sample test tube 5 filled with liquid is rotated to the lower part of the cannula 14. Then, start the cylinder 12 again to insert the cannula 14 into the sample test tube 5 filled with liquid. Repeat the above operations until all the sample test tubes 5 filled with liquid are extracted.

[0028] Although the embodiments of the present utility model have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions, and variations can be made to these embodiments without departing from the principle and spirit of the present utility model. The scope of the present utility model is defined by the appended claims and their equivalents.

Claims

1. A sample injection auxiliary device for a liquid chromatography-mass spectrometer, comprising a platform (1), characterized in that: A supporting leg (2) is provided at a bottom corner of the table (1); a sample turntable (3) is installed on the top of the table (1); slots (4) are evenly arranged on the top surface of the sample turntable (3); sample test tubes (5) are placed inside the slots (4); a bottom plate (6) is provided on the rear side of the top surface of the table (1); columns (7) are symmetrically provided on the top surface of the bottom plate (6); a threaded rod (8) is installed in the middle of the top surface of the bottom plate (6); a top plate (9) is provided on the top of the columns (7) and the threaded rod (8); A first motor (10) is installed in the middle of the top of the top plate (9), and a lifting plate (11) is sleeved on the outer walls of the upright column (7) and the threaded rod (8). A cylinder (12) is installed in the middle of the top of the lifting plate (11). A connecting plate (13) is provided on the lower drive shaft of the cylinder (12). A plug (14) is fixedly sleeved on the front side of the connecting plate (13), and an external hose (15) is provided on the top of the plug (14). A second motor (16) is installed at the bottom of the table (1) and corresponding to the sample turntable (3).

2. The sample injection auxiliary device for liquid chromatography-mass spectrometry according to claim 1, characterized in that: The sample turntable (3) and the tabletop (1) are connected in a rotational manner.

3. The sample injection auxiliary device for liquid chromatography-mass spectrometry according to claim 1, characterized in that: The upper and lower ends of the threaded rod (8) are rotatably connected to the top plate (9) and the bottom plate (6) respectively.

4. The sample injection auxiliary device for liquid chromatography-mass spectrometry according to claim 1, characterized in that: The lifting plate (11) is connected to the column (7) in a sliding manner, and the lifting plate (11) is connected to the threaded rod (8) in a threaded manner.

5. The sample injection auxiliary device for liquid chromatography-mass spectrometry according to claim 1, characterized in that: The external hose (15) passes through the lifting plate (11), and the external hose (15) and the lifting plate (11) are connected in a sliding manner.

6. The sample injection auxiliary device for liquid chromatography-mass spectrometry according to claim 1, characterized in that: The outer end of the external hose (15) is correspondingly connected to the liquid-mass spectrometer.