Fixing instrument device for directional and hierarchical recognition of pathological tissue or cell embedding

Abstract

The utility model relates to a fixing instrument device for pathological tissue or cell embedding directivity and hierarchy recognition, which comprises a first groove, a second groove and a conical fixing piece, the second groove is positioned in the first groove, and the first groove and the second groove are used for bearing pathological tissues / cells; the conical fixing parts are installed in the second grooves, one second groove corresponds to one conical fixing part, and the height of the conical fixing parts is matched with the height of the second grooves. The tissue wax block with the hollow cone is manufactured, so that the slice with the round hollow section is manufactured, the position of the round on the slice is determined by the position of the cone fixing piece in the second groove, and a worker can quickly judge the direction of the slice according to the position of the round. Meanwhile, the circular radius of the slice is gradually reduced from top to bottom through the cone structure, and the level of the slice can be judged according to the circular area of the slice.

Description

Technical Field

[0001] The utility model relates to the field of medical appliances, in particular to a fixing device for identifying the embedding directionality and hierarchy of pathological tissue or cells. Background Art

[0002] Accurate processing and analysis of pathological tissue samples are the basis of pathological research and clinical diagnosis. In pathological analysis, embedding molds are commonly used and necessary devices in tissue preparation, and are used for tissue specimen processing in hospital or laboratory pathological examinations. The embedding mold usually includes a bottom mold and an embedding box. The bottom mold has a placement table, and the embedding box is used to cover the top of the placement table. When in use, place the bottom surface of the bottom mold on a cold table, inject paraffin liquid into the bottom mold, and place the tissue in the center of the bottom mold after injecting an appropriate amount of paraffin liquid. As the bottom wax liquid cools rapidly, the tissue is immediately stuck to the bottom mold and fixed. Continue to pour wax liquid until the tissue specimen is submerged, cover the embedding box flatly above the bottom mold, fill it with wax liquid, and wait for the paraffin to condense and solidify to obtain a tissue wax block. After the tissue wax block is properly trimmed, one end of the box cover is stuck on the slicer to obtain tissue slices, and then the tissue pathology image is obtained through subsequent staining.

[0003] Traditional fixation and embedding methods have some limitations. During the fixation and embedding process, pathological tissue samples are prone to sample orientation deviation, making it difficult to identify the slice direction. In addition, pathological tissue samples generally have a complex hierarchical structure, making it difficult to clearly identify the level at which the slice is located. The above situation is not conducive to the subsequent analysis of pathological tissues and affects the comprehensiveness and accuracy of pathological diagnosis. Utility Model Content

[0004] In view of the above problems, the present application provides a fixing device for identifying the direction and hierarchy of pathological tissue or cell embedding, which is used to solve the technical problems of difficulty in distinguishing the direction of slices and difficulty in clearly identifying the hierarchy shown in the slices.

[0005] To achieve the above-mentioned purpose, in the first aspect, the present application provides a fixing instrument device for identifying the directionality and hierarchy of pathological tissue or cell embedding, comprising a first groove, a second groove and a conical fixing piece, wherein the second groove is located in the first groove, and the first groove and the second groove are used to receive pathology and / or cells; the conical fixing piece is installed inside the second groove, one second groove corresponds to one conical fixing piece, and the height of the conical fixing piece matches the height of the second groove.

[0006] As an implementation manner of the present utility model, the conical fixing piece is located on the left side of the second groove.

[0007] In this way, paraffin liquid is poured into the second groove, forming a hollow cone structure on the left side of the second groove. The slices manufactured in this way have a circular hollow cross-section of the cone, and according to the position of the circle, it is convenient for the staff to quickly identify the left part of the slice.

[0008] As an embodiment of the utility model, a triangular prism fixing piece is further provided inside the second groove, one second groove corresponds to one triangular prism fixing piece, the triangular prism fixing piece is located on the right side of the second groove, and the height of the triangular prism fixing piece matches the height of the second groove.

[0009] In this way, paraffin liquid is poured into the second groove, forming a hollow triangular prism structure on the right side of the second groove. The slices manufactured in this way have a triangular hollow cross-section of the triangular prism. According to the corresponding positions of the circle and the triangle, it is convenient to quickly identify the left and right parts of the slice and determine the direction of the slice.

[0010] As an embodiment of the utility model, a cylindrical fixing piece is provided beside the conical fixing piece, the height of the cylindrical fixing piece is equal to the height of the conical fixing piece, and the bottom area of ​​the cylindrical fixing piece is equal to the bottom area of ​​the conical fixing piece.

[0011] In this way, paraffin liquid is poured into the second groove, forming a hollow cone structure and a cylindrical structure on the left side of the second groove. The same slice manufactured in this way has a circular hollow section of a cone and a circular hollow section of a cylinder. The hollow section formed by the cone inside the device is presented on different slices, and the circular area gradually decreases from the upper slice to the lower slice, while the circular hollow section formed by the cylinder is completely equal on different slices. By comparing the areas of the hollow section of the cone and the hollow section of the cylinder, the staff can quickly and accurately identify the layer of the slice.

[0012] As an implementation manner of the present utility model, the second groove is located at the center of the first groove.

[0013] In this way, the paraffin liquid in all directions in the first groove can flow to the second groove in the center.

[0014] As an implementation manner of the present utility model, the cross-section of the first groove is a rectangle, and the four corners of the rectangle are rounded.

[0015] In this way, it is easy to process and produce regular rectangular tissue wax blocks.

[0016] As an implementation mode of the utility model, the upper cross section and the lower cross section of the second groove are both rectangular, the four corners of the rectangle are rounded, and the area of ​​the upper cross section is larger than that of the lower cross section.

[0017] In this way, the edge area of ​​the second groove forms a gentle slope, which facilitates the paraffin liquid to slowly flow into the bottom along the edge of the second groove, thereby enhancing the buffering capacity of the placement area to receive the liquid and preventing a large amount of liquid from splashing out.

[0018] As an implementation mode of the present utility model, the fixing device further comprises a first side plate and a second side plate, the first side plate is connected to the upper side of the first groove, and the second side plate is connected to the lower side of the first groove.

[0019] In this way, the first side plate and the second side plate limit the flow of the paraffin liquid, which is convenient for the rapid molding of the paraffin liquid and also convenient for the staff to move the fixing device by contacting the first side plate and the second side plate.

[0020] As an implementation mode of the utility model, the fixing device further comprises a first support plate and a second support plate, wherein the first support plate is connected to the left side of the first groove, and the second support plate is connected to the right side of the first groove.

[0021] In this way, the first support plate and the second support plate respectively support the two sides of the first groove, and the structure is more stable.

[0022] Different from the prior art, the technical solution of the present application forms a hollow cone structure by setting a conical fixing piece inside the second groove and pouring paraffin liquid inside the second groove. The slices are made with a circular hollow cross section. The position of the conical fixing piece in the second groove determines the position of the circle on the slice. The staff can quickly determine the direction of the slice according to the position of the circle. At the same time, the conical structure makes the circular radius of the slice gradually decrease from top to bottom. According to the size of the circular area of ​​the slice, the level of the slice can be determined.

[0023] The above-mentioned records related to the content of the utility model are only an overview of the technical solution of the present application. In order to enable ordinary technicians in the field to more clearly understand the technical solution of the present application, and then implement it according to the text of the specification and the contents recorded in the drawings, and to make the above-mentioned purpose and other purposes, features and advantages of the present application easier to understand, the following is an explanation in combination with the specific implementation method and drawings of the present application. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] The drawings are only used to illustrate the principles, implementation methods, applications, characteristics and effects of the specific embodiments of the present application and other related contents, and shall not be considered as limitations of the present application.

[0025] In the drawings of the specification:

[0026] Figure 1 This is a schematic diagram of the structure of a fixing device for the identification of the embedding direction and hierarchy of pathological tissue or cells in this application;

[0027] Figure 2 A top view of a fixing device for the present application for the identification of the directionality and hierarchy of pathological tissue or cell embedding;

[0028] Figure 3 This is a front view of a fixing device for the present application for the identification of the directionality and hierarchy of pathological tissue or cell embedding;

[0029] Figure 4 A side view of a fixing device for the present application for the identification of the directionality and hierarchy of pathological tissue or cell embedding;

[0030] Figure 5 This is a cross-sectional view of a fixing device for identifying the directionality and hierarchy of pathological tissue or cell embedding according to the present application.

[0031] The reference numerals in the above drawings are described as follows:

[0032] 1. The first groove,

[0033] 2. Second groove, 21. Upper section, 22. Lower section,

[0034] 3. Conical fixings,

[0035] 4. The first side panel,

[0036] 5. Second side panel,

[0037] 6. Triangular prism fixings,

[0038] 7. Cylindrical fixings,

[0039] 8. The first support plate,

[0040] 9. Second support plate. DETAILED DESCRIPTION

[0041] In order to explain in detail the possible application scenarios, technical principles, specific schemes that can be implemented, and the purposes and effects that can be achieved, the following is a detailed description of the specific embodiments listed in conjunction with the accompanying drawings. The embodiments described herein are only used to more clearly illustrate the technical solutions of the present application, and are therefore only used as examples, and cannot be used to limit the scope of protection of the present application.

[0042] Reference to "embodiment" herein means that the specific features, structures or characteristics described in conjunction with the embodiment may be included in at least one embodiment of the present application. The term "embodiment" appearing in various places in the specification does not necessarily refer to the same embodiment, nor does it particularly limit its independence or association with other embodiments. In principle, in the present application, as long as there is no technical contradiction or conflict, the various technical features mentioned in the embodiments can be combined in any way to form a corresponding implementable technical solution.

[0043] Unless otherwise defined, the technical terms used in this document have the same meanings as those generally understood by those skilled in the art to which this application belongs; the use of relevant terms in this document is only for describing specific embodiments and is not intended to limit this application.

[0044] In the description of this application, the term "and / or" is an expression used to describe the logical relationship between objects, indicating that three relationships may exist, for example, X and / or Y, which means: X exists, Y exists, and X and Y exist at the same time. In addition, the character " / " in this article generally indicates that the objects before and after are in a logical relationship of "or".

[0045] In the present application, terms such as “first” and “second” are merely used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship of quantity, priority or sequence between these entities or operations.

[0046] Without further limitations, in this application, the words "include", "comprises", "has" or other similar expressions used in the sentences are intended to cover non-exclusive inclusion. These expressions do not exclude the presence of additional elements in the process, method or product including the elements, so that the process, method or product including a series of elements may include not only those limited elements, but also other elements not explicitly listed, or also include elements inherent to such process, method or product.

[0047] Similar to the understanding in the Examination Guidelines, in this application, expressions such as "greater than", "less than", "exceed" and the like are understood to exclude the number itself; expressions such as "above", "below", "within" and the like are understood to include the number itself. In addition, in the description of the embodiments of this application, "multiple" means more than two (including two), and similar expressions related to "multiple" are also understood in this way, such as "multiple groups", "multiple times", etc., unless otherwise clearly and specifically limited.

[0048] In the description of the embodiments of the present application, space-related expressions used, such as "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "vertical", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., indicate the orientation or position relationship based on the orientation or position relationship shown in the specific embodiments or drawings, and are only for the convenience of describing the specific embodiments of the present application or facilitating the reader's understanding, and do not indicate or imply that the referred device or component must have a specific position, a specific orientation, or be constructed or operated in a specific orientation, and therefore cannot be understood as a limitation on the embodiments of the present application.

[0049] Unless otherwise expressly specified or limited, in the description of the embodiments of the present application, the terms such as "install", "connect", "connect", "fix", "set", etc. used should be understood in a broad sense. For example, the "connection" can be a fixed connection, a detachable connection, or an integrated setting; it can be a mechanical connection, an electrical connection, or a communication connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium; it can be the internal connection of two elements or the interaction relationship between two elements. For technicians in the technical field to which the present application belongs, the specific meanings of the above terms in the embodiments of the present application can be understood according to the specific circumstances.

[0050] According to some embodiments of the present application, please refer to Figures 1 to 5 The present embodiment relates to a fixing device for directional and hierarchical identification of pathological tissue or cell embedding, comprising a first groove 1, a second groove 2 and a conical fixing piece 3, wherein the second groove 2 is located in the first groove 1, and the first groove 1 and the second groove 2 are used to receive pathology and / or cells; the conical fixing piece 3 is installed inside the second groove 2, one second groove 2 corresponds to one conical fixing piece 3, and the height of the conical fixing piece 3 matches the height of the second groove 2.

[0051] The entire fixing device can be made of metal, and the conical fixing part 3 can be welded to the bottom of the second groove 2. The conical fixing part 3 mainly plays a positioning role, and the conical fixing part 3 can be set on one side of the second groove 2. The bottom radius of the conical fixing part 3 cannot be too large, and needs to match the specifications of the second groove 2. If the bottom surface coverage of the conical fixing part 3 is too large, the circular area on the lower slice will be too large, and the direction of the slice cannot be accurately identified.

[0052] When in use, the entire fixture is placed on a cold table, and an appropriate amount of paraffin liquid is injected into the first groove 1 and the second groove 2, and the tissue is placed in the second groove 2. As the paraffin liquid cools, the tissue is fixed inside the second groove 2, and the paraffin liquid is continued to be poured until the tissue specimen is submerged. The conical fixture 3 forms a hollow cone structure inside the solidified tissue wax block in the second groove 2. After the tissue wax block is properly trimmed, it is sliced, and a circular hollow is displayed on the slice. When observing the slice, the staff can judge the direction of the slice according to the position of the circular hollow, and identify the level of the slice inside the tissue wax block according to the size of the circular hollow.

[0053] According to some embodiments of the present application, optionally, the conical fixing member 3 is located on the left side of the second groove 2 .

[0054] In this way, the paraffin liquid is poured into the second groove 2, forming a hollow cone structure on the left side of the second groove 2. The slices manufactured in this way have a circular hollow of the cone, and according to the position of the circle, it is convenient for the staff to quickly identify the left part of the slice.

[0055] According to some embodiments of the present application, optionally, a triangular prism fixing piece 6 is further provided inside the second groove 2, one second groove 2 corresponds to one triangular prism fixing piece 6, the triangular prism fixing piece 6 is located on the right side of the second groove 2, and the height of the triangular prism fixing piece 6 matches the height of the second groove 2.

[0056] In this way, paraffin liquid is poured into the second groove 2, forming a hollow triangular prism structure on the right side of the second groove 2. The slices manufactured in this way have a triangular hollow cross-section with a triangular prism. According to the corresponding positions of the circle and the triangle, it is convenient to quickly identify the left and right parts of the slice and determine the direction of the slice.

[0057] The triangular prism fixing part 6 can be welded to the bottom of the second groove 2. The triangular prism fixing part 6 is mainly used for positioning, corresponding to the position of the conical fixing part 3, so that there is a circular hollow on the left side of the slice and a triangular hollow on the right side of the slice. The staff can quickly and accurately determine the direction of the slice according to the positions of these two shapes.

[0058] According to some embodiments of the present application, optionally, a cylindrical fixing member 7 is provided next to the conical fixing member 3, the height of the cylindrical fixing member 7 is equal to the height of the conical fixing member 3, and the bottom area of ​​the cylindrical fixing member 7 is equal to the bottom area of ​​the conical fixing member 3.

[0059] In this way, paraffin liquid is poured into the second groove 2, forming a hollow conical structure and a cylindrical structure on the left side of the second groove 2. The same slice manufactured in this way has a circular hollow of a cone and a circular hollow of a cylinder. The cross-section formed by the cone inside the device is presented on different slices. The circular area gradually decreases from the upper slice to the lower slice, while the circular cross-section formed by the cylinder is completely equal on different slices. By comparing the areas of the conical cross-section and the cylindrical cross-section, the staff can quickly and accurately identify the level of the slice.

[0060] The cylindrical fixing member 7 can be welded to the bottom of the second groove 2. The cylindrical fixing member 7 is mainly used to assist in identifying the level of the slice. The bottom surface of the cylindrical fixing member 7 and the bottom surface of the conical section have equal areas, which makes the slice present two circular hollows. Only the bottom slice presents two circles of equal size. The higher the slice, the greater the difference in the circular area. The staff can easily identify the location of the slice based on the comparison of the circular sizes. When it is found that the area of ​​one circle is half of the area of ​​another circle, it means that the slice is in the middle layer. Taking this as a benchmark, the larger the area difference, the higher the level of the slice, and the smaller the area difference, the lower the level of the slice.

[0061] According to some embodiments of the present application, optionally, the second groove 2 is located at the center of the first groove 1 .

[0062] In this way, the paraffin liquid in all directions in the first groove 1 can flow to the central second groove 2.

[0063] According to some embodiments of the present application, optionally, the cross-section of the first groove 1 is a rectangle, and the four corners of the rectangle are rounded.

[0064] In this way, it is easy to process and produce regular rectangular tissue wax blocks.

[0065] According to some embodiments of the present application, optionally, the upper cross-section 21 and the lower cross-section 22 of the second groove 2 are both rectangular, the four corners of the rectangle are rounded, and the area of ​​the upper cross-section 21 is larger than that of the lower cross-section 22 .

[0066] In this way, the edge area of ​​the second groove 2 forms a gentle slope, which facilitates the paraffin liquid to slowly flow into the bottom along the edge of the second groove 2, thereby enhancing the buffering capacity of the placement area to receive the liquid and preventing a large amount of liquid from splashing out.

[0067] According to some embodiments of the present application, optionally, the fixture device further includes a first side plate 4 and a second side plate 5 , wherein the first side plate 4 is connected to the upper side of the first groove 1 , and the second side plate 5 is connected to the lower side of the first groove 1 .

[0068] In this way, the first side plate 4 and the second side plate 5 limit the flow of the paraffin liquid, which is convenient for the rapid molding of the paraffin liquid, and at the same time, it is convenient for the staff to move the fixing device by contacting the first side plate 4 and the second side plate 5 .

[0069] The first side plate 4 is perpendicular to the upper side of the first groove 1, and the second side plate 5 is perpendicular to the lower side of the first groove 1. The cross-sections of the first side plate 4 and the second side plate 5 can be trapezoidal, and the trapezoid has a certain height to facilitate the staff to grasp the outer side of the groove.

[0070] According to some embodiments of the present application, optionally, the fixture device further includes a first support plate 8 and a second support plate 9 , wherein the first support plate 8 is connected to the left side of the first groove 1 , and the second support plate 9 is connected to the right side of the first groove 1 .

[0071] In this way, the first support plate 8 and the second support plate 9 respectively support the two sides of the first groove 1, and the structure is more stable.

[0072] The distances between the first support plate 8 and the second support plate 9 and the cold stage are matched with the depths of the first groove 1 and the second groove 2 , so that the support plates can support both sides of the first groove 1 .

[0073] Different from the prior art, the technical solution of the present application forms a hollow cone structure by setting a cone fixing member 3 inside the second groove 2, and injecting paraffin liquid inside the second groove 2, so that the slices are made with a circular cross-section. The position of the cone fixing member 3 in the second groove 2 determines the position of the circle on the slice, and the staff can quickly determine the direction of the slice according to the position of the circle. At the same time, the cone structure makes the circular radius of the slice gradually decrease from top to bottom, and the level of the slice can be determined according to the size of the circular area of ​​the slice.

[0074] Those skilled in the art will appreciate that, although some embodiments herein include certain features included in other embodiments but not other features, the combination of features of different embodiments is meant to be within the scope of the present application and form different embodiments. For example, in the claims, any one of the claimed embodiments may be used in any combination.

[0075] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present application, rather than to limit them; although the present application has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein by equivalents; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application, and they should all be included in the scope of the claims and specification of the present application. In particular, as long as there is no structural conflict, the various technical features mentioned in the various embodiments can be combined in any way. The present application is not limited to the specific embodiments disclosed herein, but includes all technical solutions that fall within the scope of the claims.

Claims

1. A fixing device for identifying the embedding direction and hierarchy of pathological tissue or cells, characterized in that: include: a first groove; a second groove, the second groove being located inside the first groove, the first groove and the second groove being used for receiving pathological tissues and / or cells; as well as A conical fixing member is installed inside the second groove, one second groove corresponds to one conical fixing member, and the height of the conical fixing member matches the height of the second groove.

2. A fixing device for identifying the directionality and hierarchy of pathological tissue or cell embedding according to claim 1, characterized in that: The conical fixing member is located on the left side of the second groove.

3. A fixing device for identifying the directionality and hierarchy of pathological tissue or cell embedding according to claim 2, characterized in that: A triangular prism fixing piece is also provided inside the second groove, one second groove corresponds to one triangular prism fixing piece, the triangular prism fixing piece is located on the right side of the second groove, and the height of the triangular prism fixing piece matches the height of the second groove.

4. A fixing device for identifying the directionality and hierarchy of pathological tissue or cell embedding according to claim 2, characterized in that: A cylindrical fixing piece is arranged beside the conical fixing piece, the height of the cylindrical fixing piece is equal to the height of the conical fixing piece, and the bottom area of ​​the cylindrical fixing piece is equal to the bottom area of ​​the conical fixing piece.

5. A fixing device for identifying the embedding direction and hierarchy of pathological tissue or cells according to claim 1, characterized in that: The second groove is located at the center of the first groove.

6. A fixing device for identifying the directionality and hierarchy of pathological tissue or cell embedding according to claim 1, characterized in that: The cross section of the first groove is a rectangle, and the four corners of the rectangle are rounded.

7. A fixing device for identifying the directionality and hierarchy of pathological tissue or cell embedding according to claim 1, characterized in that: The upper cross section and the lower cross section of the second groove are both rectangular, the four corners of the rectangle are rounded, and the area of ​​the upper cross section is larger than that of the lower cross section.

8. A fixing device for identifying the directionality and hierarchy of pathological tissue or cell embedding according to claim 1, characterized in that: The fixture device further includes a first side plate and a second side plate, wherein the first side plate is connected to an upper side of the first groove, and the second side plate is connected to a lower side of the first groove.

9. A fixing device for identifying the embedding direction and hierarchy of pathological tissue or cells according to claim 1, characterized in that: The fixture device further includes a first support plate and a second support plate, wherein the first support plate is connected to the left side of the first groove, and the second support plate is connected to the right side of the first groove.

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