Backflow prevention device in liquid medicine negative pressure filling system

By setting up monitoring components on the third pipeline of the negative pressure filling system of the drug liquid, the problem of foam generated by the drug liquid reflux is solved, the drug quality control effect is improved, and the accuracy and intuitiveness are achieved.

CN223001747UActive Publication Date: 2025-06-20ZHONGSHAN TRADITIONAL CHINESE MEDICINE HOSPITAL
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Patent Information

Application Number
CN202422293524.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-20
Publication Date
2025-06-20
Estimated Expiration
2034-09-20

AI Technical Summary

Technical Problem

In the negative pressure filling system of the drug liquid, certain specific agents are prone to foam when they return from the buffer tank to the storage tank, which affects the quality of the agent and the filling amount. The existing technology relies on manual experience and has poor control effect.

Method used

A anti-reflow device in a negative pressure filling system of the pharmaceutical liquid is designed, including setting up a monitoring component on the third pipeline to monitor the liquid flow in the pipe in real time, directly observe and measure the flow of the pharmaceutical liquid through the visual tube assembly and the ultrasonic flowmeter, and timely turn off the self-priming pump to avoid the reflow of the pharmaceutical liquid.

Benefits of technology

Effectively reduce or eliminate foam generated by reflux of the drug liquid, improve the quality control effect of the drug, avoid relying on manual experience, and achieve higher accuracy and intuitiveness.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides an anti-backflow device in a liquid medicine negative pressure filling system, which comprises a medicine storage tank, a self-priming pump arranged on the medicine storage tank and used for conveying liquid medicine, a first pipeline connected with the self-priming pump, a buffer tank capable of balancing system pressure connected with the first pipeline, a second pipeline connected with the buffer tank, and a liquid medicine filling device connected with the second pipeline. A third pipeline capable of recycling excessive liquid medicine is further arranged between the buffer tank and the medicine storage tank, and a monitoring assembly capable of monitoring the liquid flow in the pipeline in real time so that people can make decisions conveniently is arranged on the third pipeline. The monitoring assembly is arranged on the third pipeline to monitor the flow condition of liquid medicine in the pipeline in real time, an operator can conveniently and timely control starting and stopping of the self-priming pump to avoid backflow of the liquid medicine, foam is reduced or eliminated, and the quality control effect of the medicine is improved.
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Description

Technical Field

[0002] The utility model relates to the technical field of pharmaceutical equipment, in particular to an anti-backflow device in a negative pressure liquid filling system for liquid medicine.

Background Art

[0004] The negative pressure liquid filling system for liquid medicine is an efficient and precise filling device, which is widely used in industries such as pharmaceuticals, cosmetics, and food. This system utilizes the principle of vacuum suction. By creating a negative pressure environment inside the packaging container, the liquid medicine is naturally sucked into the container one by one to complete the filling process. In the entire negative pressure filling system, the buffer tank, the medicine storage tank, and the reflux pipeline between the two are very important functional structures. It plays an important role in maintaining the pressure balance in the system, improving the uniformity and stability of the liquid medicine, and dealing with emergencies. One important function is to release the excess liquid medicine or pressure in the buffer tank back to the medicine storage tank, thereby maintaining the pressure balance in the system and preventing adverse effects on the equipment and the filling process due to excessive pressure.

[0005] However, in pharmaceutical processing, for some special medicaments, foam will be generated when flowing back from the buffer tank to the medicine storage tank, and the foam will affect the quality and filling volume of the medicament. To avoid this situation, the current common practice is to rely on manual experience to turn off the delivery water pump on the medicine storage tank when the liquid medicine volume in the buffer tank is about to be full and generate reflux, preventing the liquid medicine from flowing back. This method depends on experience, is not accurate and intuitive enough, and has a poor quality control effect on the above-mentioned certain specific liquid medicines.

Content of the Utility Model

[0007] The purpose of the utility model is to provide an anti-backflow device in a negative pressure liquid filling system for liquid medicine that is intuitive and has an accurate control effect, aiming to solve the above problems existing in the negative pressure liquid filling system for liquid medicine in the prior art.

[0008] The utility model is realized by the following technical solutions:

[0009] An anti-backflow device in a negative pressure liquid filling system for liquid medicine, including a medicine storage tank, a self-priming pump for delivering liquid medicine is arranged on the medicine storage tank, the self-priming pump is connected with a first pipeline, the first pipeline is connected with a buffer tank capable of balancing the system pressure, the buffer tank is connected with a second pipeline, the second pipeline is connected with a liquid medicine filling device, and a third pipeline capable of recovering the excessive liquid medicine is also arranged between the buffer tank and the medicine storage tank, and a monitoring component for real-time monitoring of the liquid flow rate in the pipeline for personnel decision-making is arranged on the third pipeline.

[0010] An anti-backflow device in a negative pressure liquid filling system for liquid medicine as described above, the monitoring component includes a visual tube component arranged on the horizontal section of the third pipeline for directly observing the condition inside the pipeline.

[0011] An anti-backflow device in a liquid medicine negative pressure filling system as described above, the visual tube assembly includes two access ends provided on the horizontal section of the third pipeline, a transparent tube is provided between the two access ends, and a plurality of connecting rods are evenly arranged between the two access ends along the outer circumference of the transparent tube.

[0012] An anti-backflow device in a liquid medicine negative pressure filling system as described above, the visual tube assembly further includes a flowmeter provided on the horizontal section of the third pipeline for monitoring the liquid medicine flow rate in the tube, and the flowmeter is located between the buffer tank and the transparent tube.

[0013] An anti-backflow device in a liquid medicine negative pressure filling system as described above, the flowmeter is an ultrasonic flowmeter.

[0014] An anti-backflow device in a liquid medicine negative pressure filling system as described above, one end of the first pipeline away from the self-priming pump is connected to the bottom of the buffer tank; the buffer tank is arranged in the upper space of the liquid medicine filling device and the medicine storage tank, the top end of the second pipeline is connected to the bottom of the buffer tank, and the other end is connected to the liquid medicine filling device; one end of the third pipeline is connected to the upper side of the buffer tank, and the other end is connected to the upper end of the medicine storage tank.

[0015] An anti-backflow device in a liquid medicine negative pressure filling system as described above, a vacuum pipeline for promoting liquid medicine filling is further connected to the upper end of the liquid medicine filling device, and the other end of the vacuum pipeline is connected to a negative pressure pump that provides a vacuum environment accordingly.

[0016] An anti-backflow device in a liquid medicine negative pressure filling system as described above, further includes a central controller, and the central controller is electrically connected to the self-priming pump, the flowmeter, the liquid medicine filling device, and the negative pressure pump respectively.

[0017] Compared with the prior art, the present utility model has the following advantages:

[0018] For some specific medicaments, foam is easily generated during the backflow process, which affects the quality and filling volume of the medicament. The present utility model sets a monitoring component on the third pipeline to monitor the liquid medicine flow rate in the pipeline in real time, which is convenient for operators to control the start and stop of the self-priming pump in time to avoid liquid medicine backflow, thereby reducing or eliminating the generation of foam and improving the quality control effect of the medicament.

Description of the Drawings

[0020] In order to more clearly illustrate the technical solutions in the embodiments of the utility model, the following will briefly introduce the drawings required for the description of the embodiments.

[0021] Figure 1 It is a schematic diagram of the overall structure of the embodiment of the present utility model;

[0022] Figure 2 This is a schematic diagram of the specific structure of the visible tube assembly in the embodiment of the present utility model;

Specific Embodiment

[0024] In order to make the technical problems, technical solutions and beneficial effects solved by the present application clearer, the present application will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0025] Please refer to Figures 1 to 2 , this embodiment provides an anti-backflow device in a liquid medicine negative pressure filling system, aiming to solve the problem that some specific medicaments generate foam during the backflow process, affecting the quality and efficacy of the medicaments. It includes a medicine storage tank 1, on which a self-priming pump 2 for conveying liquid medicine is provided. The self-priming pump 2 is connected to a first pipeline 3, the first pipeline 3 is connected to a buffer tank 4 that can balance the system pressure, the buffer tank 4 is connected to a second pipeline 5, the second pipeline 5 is connected to a liquid medicine filling device 6. A third pipeline 7 for recovering excessive liquid medicine is also provided between the buffer tank 4 and the medicine storage tank 1, and a monitoring component 8 for real-time monitoring of the liquid flow rate in the pipeline to facilitate personnel decision-making is provided on the third pipeline 7.

[0026] In this embodiment, the self-priming pump 2 conveys the liquid medicine in the medicine storage tank 1 to the buffer tank 4 through the first pipeline 3. The buffer tank 4 receives the liquid medicine and balances the system pressure to ensure the stability of the liquid medicine during the filling process. The liquid medicine is conveyed from the buffer tank 4 to the liquid medicine filling device 6 through the second pipeline 5 and then filled. Since the speed at which the self-priming pump 2 conveys the liquid medicine to the buffer tank 4 is greater than the speed at which the liquid medicine filling device 6 fills the liquid medicine container, the space capacity in the buffer tank 4 will gradually become saturated. When it is saturated, the excessive liquid medicine will automatically flow into the third pipeline 7. When the monitoring component 8 monitors the liquid flow rate in the third pipeline 7, the operator can obtain an intuitive feedback, so as to timely turn off the self-priming pump 2, avoid the buffer tank 4 from continuing to receive the liquid medicine, and prevent the liquid medicine from flowing back to the medicine storage tank 1 to generate foam, which has a good quality control effect on some medicaments that should avoid liquid medicine backflow. In some other embodiments, the monitoring component 8 can also generate specific monitoring data and feedback the data to the automatic control system, or can also be connected to an alarm system to remind the operator to timely turn off the self-priming pump 2 to avoid the backflow of the liquid medicine in the buffer tank.

[0027] Further, as a preferred implementation manner rather than a limitation of this solution, the monitoring component 8 includes a visual tube component 81 disposed on the horizontal section of the third pipeline 7 for directly observing the condition inside the tube. The visual tube component 81 includes two access ends 811 disposed on the horizontal section of the third pipeline 7. A transparent tube 812 is provided between the two access ends 811. A plurality of connecting rods 813 are evenly provided between the two access ends 811 along the outer circumference of the transparent tube 812.

[0028] In this embodiment, the transparent tube 812 is located between the two access ends 811 and is used for directly observing the flow condition of the liquid medicine inside the tube. The two access ends 811 are respectively connected to both ends of the third pipeline 7 and are used for fixing the transparent tube 812 on the third pipeline 7. The access ends 811 can adopt threaded connection, flange connection or other suitable connection methods to ensure the sealing performance and stability with the third pipeline 7. A plurality of connecting rods 813 are evenly distributed along the outer circumference of the transparent tube 812 and are used for enhancing the structural strength and stability of the visual tube component 81. The connecting rods 813 can be fixedly connected to the access ends 811 and extend along the length direction of the transparent tube 812 to provide additional supporting force and prevent the visual tube component 81 from deforming or being damaged during use. The transparent tube 812 can be made of a transparent material such as glass or transparent plastic, preferably borosilicate glass, which has sufficient strength and chemical resistance to adapt to the characteristics of the liquid medicine and the working environment.

[0029] Specifically, the operator directly observes through the transparent tube 812 whether there is liquid medicine backflow in the third pipeline 7, so as to make a timely judgment on whether to turn off the self-priming pump 2.

[0030] Further, as a preferred implementation manner rather than a limitation of this solution, the visual tube component 81 further includes a flow meter 82 disposed on the horizontal section of the third pipeline 7 for monitoring the flow rate of the liquid medicine inside the tube. The flow meter 82 is located between the buffer tank 4 and the transparent tube 812, and the flow meter 82 is an ultrasonic flow meter.

[0031] In this embodiment, the operator can not only directly observe through the transparent tube 812 whether there is liquid medicine backflow in the third pipeline 7, but also the ultrasonic flow meter 82 can real-time monitor the flow rate of the liquid medicine in the pipeline and transmit the data to the control system or the display device. According to the observed situation and the flow rate data, the operator can timely adjust the rates of liquid medicine delivery and recovery to avoid the adverse impact of the liquid medicine backflow generating foam on the quality of the medicine. It should be noted that in addition to preferably using an ultrasonic flow meter for the flow meter 82, other types such as electromagnetic flow meters can also be selected.

[0032] Further, as a preferred implementation manner rather than a limitation of the present solution, one end of the first pipeline 3 away from the self-priming pump 2 is connected to the bottom of the buffer tank 4; the buffer tank 4 is arranged in the upper space of the liquid medicine filling device 6 and the medicine storage tank 1, the top end of the second pipeline 5 is connected to the bottom of the buffer tank 4, and the other end is connected to the liquid medicine filling device 6; one end of the third pipeline 7 is connected to the upper side of the buffer tank 4, and the other end is connected to the upper end of the medicine storage tank 1. In this embodiment, the connection modes and positional relationships of the first pipeline 3, the second pipeline 5 and the third pipeline 7 with the buffer tank 4, the liquid medicine filling device 6 and the medicine storage tank 1 are optimized, so that the liquid medicine can flow naturally by gravity, reducing energy consumption and equipment requirements.

[0033] Further, a vacuum pipeline 61 for promoting liquid medicine filling is also connected to the upper end of the liquid medicine filling device 6, and the other end of the vacuum pipeline 61 is connected to a negative pressure pump 62 that provides a corresponding vacuum environment. Through the negative pressure environment provided by the negative pressure pump 62 and the vacuum pipeline 61, the liquid medicine can be quickly and evenly sucked into the liquid medicine container, improving the filling efficiency and accuracy. At the same time, negative pressure filling can remove the air in the container during the filling process, avoiding the contact between the liquid medicine and the air, reducing the risks of pollution and oxidation, and improving the quality of liquid medicine production.

[0034] Furthermore, as a preferred implementation manner rather than a limitation of the present solution, a central controller 9 is also included, and the central controller 9 is electrically connected to the self-priming pump 2, the flowmeter 82, the liquid medicine filling device 6, and the negative pressure pump 62 respectively.

[0035] In this embodiment, as the control center of the liquid medicine negative pressure filling system, the central controller 9 is electrically connected to the self-priming pump 2, the flowmeter 82, the liquid medicine filling device 6, and the negative pressure pump 62 respectively, and is used to receive data of each device and send control instructions. Specifically, the central controller 9 can control the start and stop of the self-priming pump 2 according to the set filling program, and control the liquid medicine filling device 6 to perform filling operations. At the same time, the central controller 9 can also control the start and stop of the negative pressure pump 62 according to needs to provide the vacuum environment required for liquid medicine filling. In addition, it can receive the monitoring data of the flowmeter 82. When the flowmeter 82 monitors the backflow of the liquid medicine in the third pipeline 7, it issues an instruction to stop the self-priming pump 2 to prevent the liquid medicine from flowing back from the buffer tank 4 to the medicine storage tank 1.

[0036] The working principle of the present utility model:

[0037] In the present utility model, a self-priming pump transports the liquid medicine in the medicine storage tank to the buffer tank through a first pipeline. The buffer tank is used to receive the liquid medicine and balance the system pressure to ensure the stability of the liquid medicine during the filling process. The liquid medicine is transported from the buffer tank to the liquid medicine filling device through a second pipeline and then filled. Since the speed at which the self-priming pump transports the liquid medicine to the buffer tank is greater than the speed at which the liquid medicine filling device fills the medicine containers, the space capacity in the buffer tank will gradually become saturated. When the liquid medicine capacity in the buffer tank reaches saturation, the excess liquid medicine will automatically flow into a third pipeline. At this time, the monitoring component will monitor the liquid flow rate in the third pipeline in real time. Once the flow rate is detected, the operator can obtain an intuitive feedback, thereby promptly shutting down the self-priming pump to prevent the buffer tank from continuing to receive the liquid medicine and prevent the liquid medicine from flowing back into the medicine storage tank to generate foam. The monitoring component includes a visible tube component and a flow meter. The visible tube component directly observes the flow of the liquid medicine in the tube through a transparent tube, while the flow meter monitors the flow rate of the liquid medicine in the pipeline in real time and transmits the data to the control system. In addition, the monitoring component can also be electrically connected to a central controller, and the central controller automatically adjusts the liquid medicine transportation according to the monitored data or automatically shuts down the self-priming pump when backflow is detected.

[0038] Through these designs, the anti-backflow device can effectively prevent the problem that certain specific medicaments generate foam during the backflow process, which affects the quality and efficacy of the medicaments, and improve the production quality of specific liquid medicines.

[0039] The above are the implementation manners provided in combination with specific contents, and it is not determined that the specific implementation of this application is only limited to these descriptions. Any structure similar to the method structure of this application, or any technical deduction or replacement made under the premise of the concept of this application, should be regarded as the protection scope of this application.

Claims

1. A backflow prevention device in a liquid medicine negative pressure filling system, comprising a medicine storage tank (1), wherein the medicine storage tank (1) is provided with a self-priming pump (2) for conveying liquid medicine, characterized in that: The self-priming pump (2) is connected to a first pipeline (3), the first pipeline (3) is connected to a buffer tank (4) capable of balancing the system pressure, the buffer tank (4) is connected to a second pipeline (5), the second pipeline (5) is connected to a liquid medicine filling device (6), and a third pipeline (7) capable of recovering excess liquid medicine is provided between the buffer tank (4) and the medicine storage tank (1), and a monitoring component (8) capable of real-time monitoring of the flow rate of liquid in the pipeline for personnel decision-making is provided on the third pipeline (7).

2. The backflow prevention device in the liquid medicine negative pressure filling system according to claim 1 is characterized in that: The monitoring component (8) comprises a visual tube component (81) arranged on the horizontal section of the third pipeline (7) and capable of directly observing the conditions inside the pipeline.

3. The backflow prevention device in the liquid medicine negative pressure filling system according to claim 2 is characterized in that: The visual tube assembly (81) comprises two access ends (811) arranged on the horizontal section of the third pipeline (7), a transparent tube (812) is arranged between the two access ends (811), and a plurality of connecting rods (813) are evenly arranged between the two access ends (811) along the outer circumference of the transparent tube (812).

4. The backflow prevention device in the liquid medicine negative pressure filling system according to claim 3 is characterized in that: The visual tube assembly (81) further comprises a flow meter (82) disposed on the horizontal section of the third pipeline (7) for monitoring the flow rate of the liquid medicine in the pipeline, wherein the flow meter (82) is located between the buffer tank (4) and the transparent tube (812).

5. The backflow prevention device in the liquid medicine negative pressure filling system according to claim 4, characterized in that: The flow meter (82) is an ultrasonic flow meter.

6. The backflow prevention device in the liquid medicine negative pressure filling system according to claim 1, characterized in that: One end of the first pipe (3) away from the self-priming pump (2) is connected to the bottom of the buffer tank (4); the buffer tank (4) is arranged in the space above the liquid medicine filling device (6) and the medicine storage tank (1); the top end of the second pipe (5) is connected to the bottom of the buffer tank (4), and the other end is connected to the liquid medicine filling device (6); one end of the third pipe (7) is connected to the upper end of the buffer tank (4), and the other end is connected to the upper end of the medicine storage tank (1).

7. The backflow prevention device in the liquid medicine negative pressure filling system according to claim 1, characterized in that: The upper end of the liquid medicine filling device (6) is also connected to a vacuum pipe (61) for facilitating liquid medicine filling, and the other end of the vacuum pipe (61) is connected to a negative pressure pump (62) for providing a corresponding vacuum environment.

8. The backflow prevention device in the liquid medicine negative pressure filling system according to claim 1, characterized in that: It also includes a central controller (9), which is electrically connected to the self-priming pump (2), the flow meter (82), the liquid medicine filling device (6), and the negative pressure pump (62) respectively.

Citation Information

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