General plate frame for ELISA (enzyme-linked immunosorbent assay)

By designing an ELISA universal board frame including multiple rectangular frames and embedded blocks, the experimental problem caused by the unfixed fixation of the slats in the existing board frame is solved, and the stable fixation of the slats and simplified experiments are achieved.

CN223022132UActive Publication Date: 2025-06-24SUZHOU 4A BIOTECH CO LTD
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Patent Information

Application Number
CN202422157313.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-03
Publication Date
2025-06-24
Estimated Expiration
2034-09-03

AI Technical Summary

Technical Problem

Due to the inconsistent specifications of pre-packed plates of different indicators, the existing ELISA board frames require the use of adhesive strips to fix the slats in the experiment. However, the viscosity of the adhesive strips decreases during cleaning of the plate washing machine, and the slats cannot be fixed, resulting in the slats falling off and the experiment is invalid.

Method used

An ELISA universal board frame is designed, including a frame body composed of multiple rectangular frames. The rectangular frames are fixedly connected to form a cross structure, and an embedded block is set at four corner positions of the cross structure, so that the embedded blocks are abutted against the slats to achieve positioning and tightening.

Benefits of technology

This design allows slats of different sizes to be fixed in the same board frame, avoiding the use of adhesive strips, reducing experimental complexity and probability of errors, simplifying operation and more convenient reading.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses an ELISA (Enzyme Linked Immunosorbent Assay) universal plate frame which comprises a frame body, the frame body is formed by combining a plurality of rectangular frames, and the frame walls of the rectangular frames are fixedly connected with one another; a cross structure is formed by the middle portions of the four adjacent rectangular frames, and embedded blocks capable of abutting against the battens are arranged at the positions of the four corresponding corners of the cross structure. According to the ELISA universal plate frame designed by the utility model, the plate strips with different sizes and specifications can be fixed in each rectangular frame of the frame body together, and the plate strips are propped by the embedded blocks, so that the positioning and fastening of the plate strips are realized; compared with an existing plate frame, the plate frame has the advantages that the trouble of sticking strips is omitted, the plate strips can be fixed conveniently and cannot fall off, the plate using complexity and the experiment error probability in the experiment process can be reduced, the operation complexity is halved, and reading is more convenient.
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Description

Technical Field

[0001] The utility model relates to a plate frame, in particular to a general ELISA plate frame. Background Art

[0002] ELISA, that is, enzyme-linked immunosorbent assay, refers to a qualitative and quantitative detection method that binds soluble antigens or antibodies to solid-phase carriers such as polystyrene and uses the specificity of antigen-antibody binding for immune reactions.

[0003] At present, there are many existing microtiter plate specifications and different sizes. In the laboratory, several different indicators are often simultaneously subjected to ELISA experiments. In order to facilitate time memory, washing with a plate washer, and obtaining quick and accurate experimental results, generally, indicators under the same conditions are experimented at the same time. However, the pre-coated plate specifications for different indicators are not very consistent. If separate plate frames are used for experiments, even if clearly marked, it will increase the experimental difficulty. If experiments are carried out on the same plate frame, it is necessary to ensure that all the strips can be inserted into the plate frame. During the experiment, it is usually chosen to stick the edges of the strips of several indicators and the edges of the plate frame with adhesive tape to play a fixing role. However, sticking the adhesive strips is very troublesome, and after sticking, it cannot withstand the cleaning of the plate washer. The viscosity of the adhesive strips decreases in the wet state, and the strips cannot be fixed, resulting in the strips falling off in the subsequent experimental steps and even causing the experiment to be invalidated. Therefore, a general ELISA plate frame is designed to solve the above problems.

[0004] It should be noted that the above introduction of the technical background is only for the convenience of clearly and completely explaining the technical solution of the utility model and facilitating the understanding of those skilled in the art. It cannot be considered that the above technical solutions are well-known to those skilled in the art merely because these solutions are described in the background art part of the utility model. Summary of the Utility Model

[0005] To overcome the above deficiencies in the prior art, the purpose of the utility model is to provide a general ELISA plate frame.

[0006] To achieve the above purpose and other related purposes, the technical solution provided by the utility model is: a general ELISA plate frame, including a frame body, the frame body is composed of a plurality of rectangular frames combined, and the frame walls of each rectangular frame are fixedly connected to each other; the middle parts of four adjacent rectangular frames form a cross structure, and at the positions corresponding to the four corners of the cross structure, there are all inserted blocks that can resist the strips. In this solution, by using a general plate frame, strips of different sizes and specifications can be fixed together in the respective rectangular frames of the frame body, and the strips can be positioned and fastened by the inserted blocks. Compared with the existing plate frames, it can reduce the complexity of using plates in the experiment and the probability of experimental errors, halve the operation complexity, and make reading more convenient.

[0007] Furthermore, connecting holes are horizontally formed in each of the cross structures, and the connecting holes are respectively communicated with the four rectangular frames corresponding to the cross structures; the four inserts located at the same cross structure are connected into a whole through the connecting holes. In this solution, the inserts arranged at the cross structures are connected into a whole through the connecting holes, which improves the stability of the inserts at this position and facilitates the fixing of the plate strips.

[0008] Furthermore, the two side surfaces of the insert that are in contact with the inner wall of the rectangular frame are both flat and perpendicular to each other. In this solution, the two contact surfaces of the insert with the inner wall are at a right angle, which facilitates the installation of the insert at the cross structure; both contact surfaces are flat, and the installation is more stable.

[0009] Furthermore, the outer side surface of the insert is a concave arc surface, and the center line of the arc surface is vertically arranged. In this solution, the outer side surface of the insert that contacts the plate strip is set as an arc surface, which facilitates the fixing of the plate strip, and the relative space is also larger, and it can adapt to more specifications of plate strips.

[0010] Furthermore, the insert is arranged at the same height as the rectangular frame. In this solution, the contact surface between the insert and the plate strip in the height direction is ensured, and the stability between the insert and the plate strip is provided.

[0011] Furthermore, the shape of the rectangular frame is square. In this solution, the square structure is more suitable for common plate strips.

[0012] Furthermore, the widths of the two side surfaces of the insert that are in contact with the inner wall of the rectangular frame are equal and both are less than half of the width of the rectangular frame. In this solution, the insert with equal side surface widths is more stable when fixing the plate strip.

[0013] Furthermore, the number of connecting holes formed on a single cross structure is 2 to 3, and the connecting holes are vertically arranged in a uniformly distributed manner. In this solution, the vertical arrangement of the connecting holes facilitates the communication of the rectangular frames. If they are arranged horizontally, some of the connecting holes may not be able to communicate with the four rectangular frames.

[0014] Furthermore, the material of the insert is rubber. In this solution, the insert is a solid structure and is made of rubber material, which facilitates the plate strip to be inserted and embedded in the rectangular frame to maintain stability.

[0015] Furthermore, the frame body is integrally formed. In this solution, the integrally formed structure is firm and is also convenient for production.

[0016] Due to the application of the above technical solutions, the beneficial effects of the present utility model compared with the prior art are:

[0017] The ELISA universal plate frame designed by the utility model can fix strips of different sizes and specifications in each rectangular frame of the frame body, and position and fasten the strips by means of the inlay blocks against the strips. Compared with the existing plate frames, it eliminates the trouble of using adhesive strips, is convenient for fixing the strips, will not cause the strips to fall off, can reduce the complexity of using plates in the experiment process and the probability of experimental errors, halves the operation complexity, and is more convenient for reading. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 is a schematic diagram of the overall structure of the universal plate frame of the utility model;

[0019] Figure 2 is a schematic diagram of the cross structure and related structures of the utility model;

[0020] In the above drawings, 1 is the frame body; 2 is the rectangular frame; 3 is the cross structure; 4 is the inlay block; 5 is the connection hole. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0021] The following specific embodiments illustrate the implementation manners of the utility model. Those skilled in the art can easily understand other advantages and effects of the utility model from the content disclosed in this specification.

[0022] It should be noted that in the description of the utility model, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, or the orientation or positional relationship in which the utility model product is usually placed during use. It is only for the convenience of describing the utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation to the utility model. In addition, the terms "first", "second", "third", etc. are only used for descriptive distinction and cannot be understood as indicating or implying relative importance. The terms "horizontal", "vertical", "hanging", etc. do not mean that the components are required to be absolutely horizontal or hanging, but can be slightly inclined. For example, "horizontal" only means that its direction is more horizontal relative to "vertical", and does not mean that the structure must be completely horizontal, but can be slightly inclined.

[0023] In the description of the present utility model, it should also be noted that, unless otherwise clearly specified and defined, the terms "arranged", "installed", "connected", and "coupled" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium; it can be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific situations.

[0024] In the description of the present application, it should be understood that the orientation or positional relationship indicated by orientation words such as "front, rear, top, bottom, left, right", "lateral, vertical, perpendicular, horizontal" and "top, bottom", etc. is usually based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present application and simplifying the description. Without contrary instructions, these orientation words do not indicate and imply that the device or component referred to must have a specific orientation or be constructed and operated in a specific orientation. Therefore, it should not be understood as a limitation on the protection scope of the present application; the orientation words "inside, outside" refer to the inside and outside relative to the contour of each component itself.

[0025] The following will elaborate on the preferred embodiments of the present utility model in conjunction with the drawings, so that the advantages and features of the present utility model can be more easily understood by those skilled in the art, thereby making the protection scope of the present utility model more clearly defined.

[0026] Embodiment 1: Refer to the attached Figure 1 and the attached Figure 2 As shown, this embodiment provides an ELISA universal plate frame, including a frame body 1. The frame body 1 is composed of several rectangular frames 2 combined together, and the frame walls of each rectangular frame 2 are fixedly connected to each other; the middle parts of four adjacent rectangular frames 2 form a cross structure 3, and at the positions corresponding to the four corners of the cross structure 3, there are all blocks 4 that can abut against the strip. In this embodiment, by using a universal plate frame, strip plates of different sizes and specifications can be fixed together in each rectangular frame 2 of the frame body 1, and the strip plates are abutted by the blocks 4 to achieve the positioning and fastening of the strip plates; compared with the existing plate frames, it can reduce the complexity of using plates in the experiment process and the probability of experimental errors, halve the operation complexity, and make the reading more convenient.

[0027] Embodiment 2: Refer to the attached Figure 1 and the attached Figure 2As shown in the figure, this embodiment is a further improvement based on Embodiment 1. The specific method is as follows: Connecting holes 5 are horizontally opened on each cross structure 3, and the connecting holes 5 are respectively communicated with the four rectangular frames 2 corresponding to the cross structure 3; The four inserts 4 located at the same cross structure 3 are connected into one body through the connecting holes 5. In this embodiment, the inserts 4 arranged at the cross structure 3 are connected into one body through the connecting holes 5, which improves the stability of the inserts 4 at this position and facilitates fixing the plate strips. The four inserts 4 connected through the connecting holes 5 can be arranged at the four corners of the cross structure 3 through a mold, and the inserts 4 at the four corners are formed by injecting glue. The liquid colloid flows through the connecting holes 5, so that the inserts 4 at the four corners are connected; Or the wire material can pass through the connecting holes 5 along two perpendicular diagonals and be inserted into the corresponding inserts 4, and the wire material is connected to the inserts 4 at the four corners by tying or other means; The connection methods of the four inserts 4 at the cross structure 3 include but are not limited to the above two methods.

[0028] Embodiment 3: Refer to the attached Figure 1 and the attached Figure 2 As shown in the figure, this embodiment is a further improvement based on Embodiment 1. The specific method is as follows: Both sides of the insert 4 in contact with the inner wall of the rectangular frame 2 are flat and perpendicular to each other. In this embodiment, the two contact surfaces of the insert 4 with the inner wall are at a right angle, which is convenient for installing the insert 4 at the cross structure 3; Both contact surfaces are flat, so the installation is more stable.

[0029] Embodiment 4: Refer to the attached Figure 1 and the attached Figure 2 As shown in the figure, this embodiment is a further improvement based on Embodiment 1. The specific method is as follows: The outer side surface of the insert 4 is an inwardly concave arc surface, and the center line of the arc surface is vertically arranged. In this embodiment, the outer side surface of the insert 4 in contact with the plate strip is set as an arc surface, which is convenient for fixing the plate strip, and the relative space is also larger, and it can adapt to more specifications of plate strips.

[0030] Embodiment 5: Refer to the attached Figure 2 As shown in the figure, this embodiment is a further improvement based on Embodiment 1. The specific method is as follows: The insert 4 is arranged at the same height as the rectangular frame 2. In this embodiment, the contact surface between the insert 4 and the plate strip in the height direction is ensured, and the stability between the insert 4 and the plate strip is provided.

[0031] Embodiment 6: Refer to the attached Figure 1 As shown in the figure, this embodiment is a further improvement based on Embodiment 1. The specific method is as follows: The shape of the rectangular frame 2 is a square. In this embodiment, the square structure is more suitable for common plate strips.

[0032] Embodiment 7: Refer to the attached Figure 1As shown, this embodiment is a further improvement on the basis of the first embodiment, and its specific method is: the widths of the two sides of the insert 4 that contact the inner wall of the rectangular frame 2 are equal and both are less than half of the width of the rectangular frame 2. In this embodiment, the insert 4 with equal side widths is more stable when fixing the slats.

[0033] Embodiment 8: See attached Figure 2 As shown, this embodiment is a further improvement on the basis of the first embodiment, and its specific method is: the number of connection holes 5 set on a single cross structure 3 is 2 to 3, and each connection hole 5 is evenly arranged vertically. In this embodiment, the number of connection holes 5 is 2, 3 or 4, and the connection holes 5 are arranged vertically to facilitate the connection of the rectangular frames 2. If they are arranged horizontally, some of the connection holes 5 may not be able to connect the four rectangular frames 2.

[0034] Embodiment 9: Not shown in the drawings, this embodiment is a further improvement on the basis of embodiment 1, and its specific method is as follows: the material of the insert block 4 is rubber. In this embodiment, the insert block 4 is a solid structure, and the material of the insert block 4 includes but is not limited to rubber material. Any material that can fix the slats and has good ductility can be selected, so that slats of different sizes can be embedded in the rectangular frame 2. The use of rubber material makes it easier for the slats to be inserted and embedded in the rectangular frame 2 to remain stable.

[0035] Embodiment 10: See attached Figure 1 As shown, this embodiment is a further improvement on the basis of the first embodiment, and its specific method is: the frame body 1 is integrally formed. In this embodiment, the integrally formed structure is firm and easy to produce.

[0036] The ELISA universal plate frame designed by the utility model can fix plate strips of different sizes together in each rectangular frame of the frame body, and the plate strips are pressed against by the embedded blocks to achieve positioning and fastening of the plate strips; compared with the existing plate frame, the trouble of adhesive strips is saved, the plate strips are easy to fix, and the plate strips will not fall off, which can reduce the complexity of using the plate during the experiment and the probability of experimental errors, the operation complexity is halved, and the reading is more convenient.

[0037] The above implementation modes are only for illustrating the technical concept and features of the utility model, and their purpose is to allow people familiar with this technology to understand the content of the utility model and implement it. It cannot be used to limit the protection scope of the utility model. Any equivalent changes or modifications made according to the spirit of the utility model should be included in the protection scope of the utility model.

Claims

1. An ELISA universal plate frame, characterized in that: The invention comprises a frame body (1), wherein the frame body (1) is composed of a plurality of rectangular frames (2), and the frame walls of the rectangular frames (2) are fixedly connected to each other; the middle parts of four mutually adjacent rectangular frames (2) form a cross structure (3), and the positions of the four corners corresponding to the cross structure (3) are all provided with inserts (4) capable of resisting against the slats.

2. An ELISA universal plate frame according to claim 1, characterized in that: A connecting hole (5) is provided on each of the cross structures (3) in the horizontal direction, and the connecting holes (5) are respectively connected to the four rectangular frames (2) corresponding to the cross structures (3); the four inserts (4) located at the same cross structure (3) are connected as a whole through the connecting holes (5).

3. An ELISA universal plate frame according to claim 1, characterized in that: The two side surfaces of the insert (4) that contact the inner wall of the rectangular frame (2) are both planes and are arranged perpendicular to each other.

4. An ELISA universal plate frame according to claim 1, characterized in that: The outer side surface of the insert (4) is a concave arc surface, and the center line of the arc surface is arranged vertically.

5. An ELISA universal plate frame according to claim 1, characterized in that: The insert (4) is arranged at the same height as the rectangular frame (2).

6. An ELISA universal plate frame according to claim 1, characterized in that: The rectangular frame (2) is in the shape of a square.

7. An ELISA universal plate frame according to claim 1, characterized in that: The widths of the two side surfaces of the insert (4) that contact the inner wall of the rectangular frame (2) are equal and both are less than half of the width of the rectangular frame (2).

8. An ELISA universal plate frame according to claim 1, characterized in that: The number of connection holes (5) provided on a single cross structure (3) is 2 to 3, and the connection holes (5) are evenly distributed vertically.

9. The ELISA universal plate frame according to claim 1, characterized in that: The material of the insert (4) is rubber.

10. The ELISA universal plate frame according to claim 1, characterized in that: The frame body (1) is integrally formed.