Liquid driving and automatic detection device based on micro-fluidic chip

Abstract

The utility model discloses a liquid driving and automatic detection device based on a micro-fluidic chip, which comprises a main body assembly and a detection platform, and a sampling mechanism is arranged at the top of the detection platform; the adjusting assembly comprises a sampling vessel fixed to the top of the detection platform, a sampling needle is arranged in the sampling vessel, a supporting ring is fixed to the inner wall of the sampling vessel, a sealing shell and a positioning shell are arranged at the top of the sampling vessel, and the adjusting assembly further comprises a positioning piece which is arranged in the sampling vessel and comprises an extrusion sleeve fixed to the bottom of the sealing shell; according to the utility model, through the arrangement of the adjusting assembly, after the sampling mechanism takes away the corresponding sampling needle head, the notch for placing the sampling needle head corresponding to the sampling vessel can be automatically sealed, so that the notch is prevented from being polluted.

Description

Technical Field

[0001] The utility model relates to the technical field of detection devices, in particular to a liquid driving and automatic detection device based on a microfluidic chip. Background Art

[0002] The liquid driving and automatic detection device based on a microfluidic chip is based on a microfluidic chip. According to the need of the order of combination of reactants, by controlling the flow of the sample liquid, the order and degree of different biochemical reactions are controlled, and a series of processes such as sampling, injection into detection, and collection are automatically completed.

[0003] However, when the existing automatic detection device is in use, after the sampling needle in the sampling dish is taken away, the notch for placing the sampling needle will be exposed to the air, so that pollutants in the air will enter the notch. When the sampling needle is placed in the sampling dish again next time, the sampling needle will be contaminated. Summary of the Utility Model

[0004] The purpose of this part is to outline some aspects of the embodiments of the utility model and briefly introduce some preferred embodiments. Some simplifications or omissions may be made in this part, as well as in the abstract of the specification and the title of the utility model of this application, to avoid obscuring the purpose of this part, the abstract of the specification, and the title of the utility model. However, such simplifications or omissions shall not be used to limit the scope of the utility model.

[0005] In view of the above and / or problems existing in the existing liquid driving and automatic detection device based on a microfluidic chip, the utility model is proposed.

[0006] Therefore, the problem to be solved by the utility model is that the sampling dish of the existing automatic detection device does not have a good sealing mechanism, and the notch for placing the sampling needle will be exposed to the air, so that pollutants in the air contaminate the notch.

[0007] To solve the above technical problems, the utility model provides the following technical solution: A liquid driving and automatic detection device based on a microfluidic chip, which includes a main body component, including a detection platform, and a sampling mechanism is arranged on the top of the detection platform;

[0008] An adjustment component, including a sampling dish fixed on the top of the detection platform, a sampling needle is arranged in the sampling dish, a support ring is fixed on the inner wall of the sampling dish, and a sealing shell and a positioning shell are arranged on the top of the sampling dish.

[0009] As a preferred scheme of the liquid driving and automatic detection device based on a microfluidic chip of the utility model, wherein: The adjustment component further includes a positioning member, which is arranged in the sampling dish and includes an extrusion sleeve fixed on the bottom of the sealing shell.

[0010] As a preferred solution of the liquid driving and automatic detection device based on a microfluidic chip according to the present utility model, wherein: a first spring is arranged inside the extrusion sleeve, a support sleeve is arranged on the surface of the extrusion sleeve, the support sleeve is fixed inside the sampling dish, and two ends of the first spring are respectively fixed to the inner wall of the support sleeve and the inner wall of the extrusion sleeve.

[0011] As a preferred solution of the liquid driving and automatic detection device based on a microfluidic chip according to the present utility model, wherein: the adjusting assembly further includes an adjusting member arranged inside the sampling dish, including a sleeve fixed inside the sampling dish.

[0012] As a preferred solution of the liquid driving and automatic detection device based on a microfluidic chip according to the present utility model, wherein: a top block is slidably connected inside the sleeve, a second spring is arranged inside the sleeve, and two ends of the second spring are respectively fixed to the inner wall of the sleeve and the inner wall of the top block.

[0013] As a preferred solution of the liquid driving and automatic detection device based on a microfluidic chip according to the present utility model, wherein: a sealing cover plate is arranged inside the sampling dish, the sealing cover plate is slidably connected inside the sampling dish, and a driving block is fixedly connected to one side of the sealing cover plate.

[0014] As a preferred solution of the liquid driving and automatic detection device based on a microfluidic chip according to the present utility model, wherein: a support shell is fixedly connected to the top of the sealing cover plate, an adjusting block is slidably arranged on the support shell, a third spring is arranged inside the adjusting block, and two ends of the third spring are respectively fixed to the inner wall of the adjusting block and the inner wall of the support shell.

[0015] As a preferred solution of the liquid driving and automatic detection device based on a microfluidic chip according to the present utility model, wherein: the adjusting assembly further includes a driving member arranged on the detection platform, including a support block fixed on the detection platform, a slide bar is fixed inside the support block, a threaded rod is rotatably connected inside the support block, and a driving motor is fixedly connected to one side of the support block.

[0016] As a preferred solution of the liquid driving and automatic detection device based on a microfluidic chip according to the present utility model, wherein: a threaded sleeve is rotationally connected to the surface of the threaded rod through threads, and a dial rod is fixed on the surface of the threaded sleeve.

[0017] As a preferred solution of the liquid driving and automatic detection device based on a microfluidic chip according to the present utility model, wherein: a microfluidic chip is arranged on one side of the sampling dish, and a storage box is arranged on the top of the detection platform.

[0018] The beneficial effects of the present utility model are as follows: By providing an adjustment component, after the sampling mechanism removes the corresponding sampling needle, the notch of the sampling dish for placing the sampling needle can be automatically sealed, preventing the notch from being contaminated. Description of the Drawings

[0019] In order to more clearly illustrate the technical solutions of the embodiments of the present utility model, the drawings required for the description of the embodiments will be briefly introduced below. Obviously, the drawings in the following description are only some embodiments of the present utility model. For those of ordinary skill in the art, without creative efforts, other drawings can also be obtained based on these drawings. Among them:

[0020] Figure 1 It is a structural diagram of a liquid driving and automatic detection device based on a microfluidic chip.

[0021] Figure 2 It is for the Figure 1 local enlarged structure diagram at position A of the liquid driving and automatic detection device based on a microfluidic chip.

[0022] Figure 3 It is for the Figure 1 local enlarged structure diagram at position B of the liquid driving and automatic detection device based on a microfluidic chip.

[0023] Figure 4 It is a connection structure diagram of the sampling dish and the sealing shell of the liquid driving and automatic detection device based on a microfluidic chip.

[0024] Figure 5 It is a partial sectional structure diagram of the sampling dish of the liquid driving and automatic detection device based on a microfluidic chip.

[0025] Figure 6 It is a connection structure diagram of the sealing shell and the positioning shell of the liquid driving and automatic detection device based on a microfluidic chip.

[0026] In the figure: main body component, 100; detection platform, 101; sampling mechanism, 102; microfluidic chip, 103; storage box, 104; adjustment component, 200; sampling dish, 201a; sampling needle, 201b; support ring, 201c; sealing shell, 201d; positioning shell, 201e; positioning part, 202; extrusion sleeve, 202a; first spring, 202b; support sleeve, 202c; adjustment part, 203; sleeve, 203a; top block, 203b; second spring, 203c; sealing cover plate, 203d; driving block, 203e; support shell, 203f; adjustment block, 203g; third spring, 203h; driving part, 204; support block, 204a; sliding rod, 204b; threaded rod, 204c; driving motor, 204d; threaded sleeve, 204e; lever, 204f. Detailed implementation manners

[0027] To make the above objects, features and advantages of the present utility model more obvious and understandable, the following detailed description of the specific implementation manners of the present utility model will be given with reference to the accompanying drawings of the specification.

[0028] In the following description, many specific details are set forth in order to fully understand the present utility model. However, the present utility model can also be implemented in other ways different from those described herein. Those skilled in the art can make similar generalizations without departing from the connotation of the present utility model. Therefore, the present utility model is not limited by the specific embodiments disclosed below.

[0029] Secondly, the so-called "one embodiment" or "embodiment" herein refers to a specific feature, structure or characteristic that can be included in at least one implementation manner of the present utility model. The appearances of "in one embodiment" in different places in this specification do not all refer to the same embodiment, nor are they separate or selectively exclusive embodiments from other embodiments.

[0030] Embodiment 1

[0031] Referring to Figures 1 to 6 , this is the first embodiment of the present utility model. This embodiment provides a liquid driving and automatic detection device based on a microfluidic chip. The liquid driving and automatic detection device based on a microfluidic chip includes a main body component 100, including a detection platform 101. A sampling mechanism 102 is provided on the top of the detection platform 101;

[0032] The adjustment component 200 includes a sampling dish 201a fixed on the top of the detection platform 101. A sampling needle 201b is arranged in the sampling dish 201a. A support ring 201c is fixed on the inner wall of the sampling dish 201a. A sealing shell 201d and a positioning shell 201e are arranged on the top of the sampling dish 201a.

[0033] The sampling dish 201a is used to hold the sampling needle 201b. Multiple sampling needles 201b are arranged in the sampling dish 201a. The sealing shell 201d is used to cooperate with the positioning shell 201e to seal the sampling needle 201b. And after the sampling needle 201b is taken out, the placement notch of the sampling needle 201b can be sealed. The support ring 201c is used to support the sampling needle 201b. The top of the sampling needle 201b is an iron metal ring. The sampling mechanism 102 adsorbs the sampling needle 201b through an electromagnetic coil to pick up the sampling needle 201b.

[0034] Specifically, the adjusting assembly 200 further includes a positioning member 202, which is arranged in the sampling dish 201a and includes an extrusion sleeve 202a fixed to the bottom of the sealing shell 201d.

[0035] The extrusion sleeve 202a is used to push the sealing shell 201d so that the sealing shell 201d can move to the top of the sampling needle 201b.

[0036] Specifically, a first spring 202b is arranged in the extrusion sleeve 202a, and a support sleeve 202c is arranged on the surface of the extrusion sleeve 202a. The support sleeve 202c is fixed in the sampling dish 201a. Both ends of the first spring 202b are respectively fixed to the inner wall of the support sleeve 202c and the inner wall of the extrusion sleeve 202a.

[0037] The first spring 202b is in a compressed state and is used to push the extrusion sleeve 202a. The support sleeve 202c is used to improve the stability of the movement of the extrusion sleeve 202a.

[0038] Embodiment 2

[0039] Refer to Figures 1 to 6 , which is the second embodiment of the present utility model. This embodiment is based on the previous embodiment.

[0040] Specifically, the adjusting assembly 200 further includes an adjusting member 203, which is arranged in the sampling dish 201a and includes a sleeve 203a fixed in the sampling dish 201a.

[0041] The sleeve 203a is fixed in the sampling dish 201a, and the number of the sleeves 203a is multiple.

[0042] Specifically, a top block 203b is slidably connected in the sleeve 203a. A second spring 203c is arranged in the sleeve 203a. Both ends of the second spring 203c are respectively fixed to the inner wall of the sleeve 203a and the inner wall of the top block 203b.

[0043] The second spring 203c is in a compressed state, so that the second spring 203c has a certain driving force on the top block 203b.

[0044] Specifically, a sealing cover plate 203d is arranged inside the sampling dish 201a. The sealing cover plate 203d is slidably connected inside the sampling dish 201a, and a driving block 203e is fixedly connected to one side of the sealing cover plate 203d.

[0045] The sealing cover plate 203d is used to seal the sampling dish 201a, and the driving block 203e is used to drive the sealing cover plate 203d to move.

[0046] Specifically, a support shell 203f is fixedly connected to the top of the sealing cover plate 203d. An adjusting block 203g slides in the support shell 203f. A third spring 203h is arranged inside the adjusting block 203g. Both ends of the third spring 203h are respectively fixed to the inner wall of the adjusting block 203g and the inner wall of the support shell 203f.

[0047] The support shell 203f is used to position and support the adjusting block 203g. The third spring 203h is in a compressed state, so that the end of the adjusting block 203g can extend out of the sealing cover plate 203d.

[0048] Specifically, the adjusting assembly 200 further includes a driving member 204. The driving member 204 is arranged on the detection platform 101 and includes a support block 204a fixed on the detection platform 101. A sliding rod 204b is fixed inside the support block 204a. A threaded rod 204c is rotatably connected inside the support block 204a. A driving motor 204d is fixedly connected to one side of the support block 204a.

[0049] The support block 204a is used to support the sliding rod 204b and the threaded rod 204c. The output end of the driving motor 204d is fixedly connected to the end of the threaded rod 204c. Starting the driving motor 204d can drive the threaded rod 204c to rotate.

[0050] Specifically, a threaded sleeve 204e is rotatably connected to the surface of the threaded rod 204c through threads. A dial rod 204f is fixed on the surface of the threaded sleeve 204e.

[0051] When the threaded rod 204c rotates, it can drive the threaded sleeve 204e to move, so that the threaded sleeve 204e drives the dial rod 204f to move. Thus, the dial rod 204f squeezes the driving block 203e, so that the driving block 203e drives the sealing cover plate 203d to move. The dial rod 204f slides on the surface of the sliding rod 204b, so that the dial rod 204f can move stably.

[0052] Specifically, a microfluidic chip 103 is arranged on one side of the sampling dish 201a, and a storage box 104 is arranged on the top of the detection platform 101.

[0053] The microfluidic chip 103 is used to control the flow of the sample liquid to control the sequence and degree of different biochemical reactions. The storage box 104 is used to store the sampling needle 201b after use.

[0054] During use, when it is necessary to take the sampling needle 201b in the sampling dish 201a, the control mechanism set in the detection platform 101 is used to control the driving motor 204d, so that the driving motor 204d drives the threaded rod 204c to rotate. At this time, when the threaded rod 204c rotates, it can drive the threaded sleeve 204e to move, so that the threaded sleeve 204e drives the lever 204f to move, thereby enabling the lever 204f to squeeze the driving block 203e, so that the driving block 203e drives the sealing cover plate 203d to move. As the sealing cover plate 203d moves, it can drive the adjusting block 203g to move towards the sealing shell 201d, so that the adjusting block 203g pushes the sealing shell 201d, thereby exposing the sampling needle 201b below the sealing shell 201d. At this time, the driving motor 204d stops rotating.

[0055] The sampling mechanism 102 is used to take out the sampling needle 201b from the sampling dish 201a. At this time, the driving motor 204d can continue to rotate, so that the adjusting block 203g drives the sealing shell 201d to continue to move. As the sealing shell 201d moves, the top block 203b pushes the adjusting block 203g under the elastic force of the second spring 203c, so that the adjusting block 203g is received into the sealing cover plate 203d. At this time, the blocking of the adjusting block 203g on the sealing shell 201d is released. Since the end of the top block 203b is provided with a rounded corner, under the reset elastic force of the first spring 202b, the end of the sealing shell 201d can squeeze the top block 203b downward, so that the sealing shell 201d can move towards the positioning shell 201e. Through the cooperation of the sealing shell 201d and the positioning shell 201e, the placement notch of the sampling needle 201b can be sealed.

[0056] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not restrictive. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present invention can be modified or equivalently replaced without departing from the spirit and scope of the technical solutions of the present invention, and they should all be covered within the scope of the technical solutions of the present invention.

Claims

1. A liquid driving and automated detection device based on a microfluidic chip, characterized in that: include, The main body component (100) comprises a detection platform (101), wherein a sampling mechanism (102) is arranged on the top of the detection platform (101); The adjustment component (200) comprises a sampling dish (201a) fixed to the top of the detection platform (101), a sampling needle (201b) being arranged in the sampling dish (201a), a supporting ring (201c) being fixed to the inner wall of the sampling dish (201a), and a sealing shell (201d) and a positioning shell (201e) being arranged on the top of the sampling dish (201a).

2. The liquid driving and automatic detection device based on a microfluidic chip according to claim 1, characterized in that: The adjustment component (200) further comprises a positioning member (202) which is arranged in the sampling dish (201a) and comprises a pressing sleeve (202a) fixed to the bottom of the sealing shell (201d).

3. The liquid driving and automatic detection device based on a microfluidic chip according to claim 2, characterized in that: A first spring (202b) is arranged inside the extrusion sleeve (202a), a support sleeve (202c) is arranged on the surface of the extrusion sleeve (202a), the support sleeve (202c) is fixed inside the sampling dish (201a), and two ends of the first spring (202b) are respectively fixed to the inner wall of the support sleeve (202c) and the inner wall of the extrusion sleeve (202a).

4. The liquid driving and automatic detection device based on a microfluidic chip according to claim 3, characterized in that: The adjustment component (200) further comprises an adjustment member (203), which is arranged in the sampling dish (201a) and comprises a sleeve (203a) fixed in the sampling dish (201a).

5. The liquid driving and automatic detection device based on a microfluidic chip according to claim 4, characterized in that: A top block (203b) is slidably connected inside the sleeve (203a), a second spring (203c) is arranged inside the sleeve (203a), and two ends of the second spring (203c) are respectively fixed to the inner wall of the sleeve (203a) and the inner wall of the top block (203b).

6. The liquid driving and automatic detection device based on a microfluidic chip according to claim 5, characterized in that: A sealing cover plate (203d) is provided in the sampling dish (201a); the sealing cover plate (203d) is slidably connected in the sampling dish (201a); and a driving block (203e) is fixedly connected to one side of the sealing cover plate (203d).

7. The liquid driving and automatic detection device based on a microfluidic chip according to claim 6, characterized in that: The top of the sealing cover plate (203d) is fixedly connected to a support shell (203f), an adjustment block (203g) is slidably mounted on the support shell (203f), a third spring (203h) is arranged inside the adjustment block (203g), and two ends of the third spring (203h) are respectively fixed to the inner wall of the adjustment block (203g) and the inner wall of the support shell (203f).

8. The liquid driving and automatic detection device based on a microfluidic chip according to claim 7, characterized in that: The adjustment component (200) further comprises a driving member (204), the driving member (204) being arranged on the detection platform (101) and comprising a support block (204a) fixed on the detection platform (101), a sliding rod (204b) being fixed inside the support block (204a), a threaded rod (204c) being rotatably connected inside the support block (204a), and a driving motor (204d) being fixedly connected to one side of the support block (204a).

9. The liquid driving and automatic detection device based on a microfluidic chip according to claim 8, characterized in that: The surface of the threaded rod (204c) is rotatably connected to a threaded sleeve (204e) through a thread, and a shifting rod (204f) is fixed to the surface of the threaded sleeve (204e).

10. The liquid driving and automatic detection device based on a microfluidic chip according to claim 8 or 9, characterized in that: A microfluidic chip (103) is arranged on one side of the sampling dish (201a), and a storage box (104) is arranged on the top of the detection platform (101).

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