Rat arthritis modeling auxiliary device

Abstract

The utility model provides a rat arthritis modeling auxiliary device which comprises a box body, a running belt is arranged on one side of the bottom of the inner wall of the box body, an adjusting box is arranged at one end of the interior of the box body, a fixing assembly is arranged between the adjusting box and the box body, the fixing assembly comprises a sliding groove, and the sliding groove is arranged in the box body. A sliding groove is formed in one end of the adjusting box, a sliding block is slidably connected into the sliding groove, the sliding block is connected with the adjusting box, a threaded block is connected to the surface of the sliding block, a threaded sleeve is connected to the surface of the threaded block in a threaded mode, a fixing frame is installed at one end of the adjusting box, and a drinking bottle is arranged in the fixing frame. According to the rat arthritis modeling auxiliary device, the adjusting box is arranged in the box body, the sliding groove, the sliding block, the threaded block and the threaded sleeve are operated in a matched mode, the length between the box body and the adjusting box can be adjusted according to the size of a rat, replacement operation of the box body and the adjusting box is not needed, and operation is convenient. Therefore, the convenience of rat feeding can be improved.

Description

Technical Field

[0001] The utility model relates to the field of medical instruments, in particular to an auxiliary device for modeling rat arthritis. Background Technique

[0002] Due to the advantages of small size, large number of offspring, short life cycle and gene knockout, mice are important animal models for studying the pathogenesis, risk factors and treatment methods of osteoarthritis. At present, the modeling methods for knee osteoarthritis in mice mainly include spontaneous models and artificial induction models.

[0003] Because of the light weight of mice and the limited joint activity during long-term breeding in cages, it is difficult to simulate the daily joint movement and upright load-bearing of humans for effective arthritis modeling. The artificial induction model mainly constructs knee osteoarthritis by injecting drugs into the joint cavity to damage the extracellular matrix of articular cartilage cells, or by surgically cutting the anterior cruciate ligament and medial collateral ligament and combining partial medial meniscus injury.

[0004] In the patent application with the publication number CN209030822U proposed in the prior art, during the process of modeling knee osteoarthritis in mice, it can simulate the upright state of the human knee joint, and its mechanical properties are similar to those of the human knee joint. At the same time, it can promote the operation of the crawler through a mouse gait analyzer, forcing the mouse to perform joint walking movements, and can control the amount of exercise, simulating the state of the human knee joint from both mechanical and movement characteristics, so as to be closer to the pathogenesis characteristics of human knee osteoarthritis, and can better study the pathogenesis and process of knee osteoarthritis, thus better assisting mice in modeling knee osteoarthritis.

[0005] However, the feeding cages and food cages used for rats are of fixed sizes and are connected by splicing. During long-term breeding of rats, the length of the rats will increase, resulting in the need to replace the feeding cages and food cages, and the size between the feeding cages and food cages cannot be adjusted according to the size of the rats.

[0006] Therefore, it is necessary to provide an auxiliary device for modeling rat arthritis to solve the above technical problems. Content of the Utility Model

[0007] The utility model provides an auxiliary device for modeling rat arthritis, which solves the problem that during long-term breeding of rats, the length of the rats will increase, resulting in the need to replace the feeding cages and food cages, and the size between the feeding cages and food cages cannot be adjusted according to the size of the rats.

[0008] To solve the above technical problems, an auxiliary device for modeling rat arthritis provided by the utility model includes:

[0009] A box body, on one side of the bottom of the inner wall of the box body, a running belt is provided;

[0010] An adjustment box, the adjustment box is arranged at one end inside the box body, a fixing component is arranged between the adjustment box and the box body, the fixing component includes a sliding groove, a slider is slidably connected inside the sliding groove, the slider is connected to the adjustment box, a threaded block is connected to the surface of the slider, and a threaded sleeve is threadedly connected to the surface of the threaded block.

[0011] Preferably, a fixing frame is installed at one end of the adjustment box, and a water bottle is arranged inside the fixing frame.

[0012] Preferably, a food box is arranged at one end of the adjustment box and on one side of the water bottle.

[0013] Preferably, an opening is provided at one end of the box body, and a movable plate is arranged inside the opening.

[0014] Preferably, an installation through groove adapted to the movable plate is provided on one side of the top of the box body.

[0015] Preferably, a disassembly component is arranged on the surface of the box body, the disassembly component includes a filter plate, fixing blocks are connected to both sides of the top and bottom of the filter plate, and fixing grooves adapted to the fixing blocks are provided on the surface of the box body.

[0016] Preferably, fixing bolts are arranged between the box body and the fixing blocks.

[0017] Compared with the related art, a rat arthritis modeling auxiliary device provided by the present invention has the following beneficial effects:

[0018] The present invention provides a rat arthritis modeling auxiliary device. By the cooperative operation among the adjustment box, the sliding groove, the slider, the threaded block and the threaded sleeve arranged inside the box body, the length between the box body and the adjustment box can be adjusted according to the size of the rat, without the need to replace the box body and the adjustment box, thereby increasing the convenience of rat breeding. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 is a schematic structural diagram of a first embodiment of a rat arthritis modeling auxiliary device provided by the present invention;

[0020] Figure 2 is Figure 1 the overall three-dimensional structural diagram of the device shown;

[0021] Figure 3 is Figure 2 the enlarged schematic diagram of part A shown;

[0022] Figure 4 is Figure 1 an isometric structural schematic diagram of the whole device shown;

[0023] Figure 5 is a structural schematic diagram of the second embodiment of a rat arthritis modeling assistance device provided by the present utility model;

[0024] Figure 6 is Figure 5 an enlarged schematic diagram of part B shown.

[0025] Reference numerals in the figure: 1, box body; 2, running belt; 3, adjustment box;

[0026] 4, fixing assembly; 41, chute; 42, slider; 43, threaded block; 44, threaded sleeve;

[0027] 5, fixing frame; 6, drinking water bottle; 7, food box; 8, open end; 9, installation through groove; 10, movable plate;

[0028] 11, disassembly assembly; 111, filter plate; 112, fixing block; 113, fixing groove; 114, fixing bolt. Specific embodiments

[0029] The present utility model will be further described below in conjunction with the accompanying drawings and embodiments.

[0030] First embodiment

[0031] Please refer to Figure 1 , Figure 2 , Figure 3 and Figure 4 , wherein Figure 1 is a structural schematic diagram of the first embodiment of a rat arthritis modeling assistance device provided by the present utility model; Figure 2 is Figure 1 a three-dimensional structural schematic diagram of the whole device shown; Figure 3 is Figure 2 an enlarged schematic diagram of part A shown; Figure 4 is Figure 1 an isometric structural schematic diagram of the whole device shown. A rat arthritis modeling assistance device includes:

[0032] a box body 1, on one side of the bottom of the inner wall of the box body 1, there is provided a running belt 2;

[0033] Adjusting box 3, the adjusting box 3 is arranged at one end inside the box body 1, a fixing component 4 is arranged between the adjusting box 3 and the box body 1, the fixing component 4 includes a sliding groove 41, a slider 42 is slidably connected inside the sliding groove 41, the slider 42 is connected to the adjusting box 3, a threaded block 43 is connected to the surface of the slider 42, and a threaded sleeve 44 is threadedly connected to the surface of the threaded block 43.

[0034] The adjusting box 3 is installed at one end inside the box body 1, and the adjusting box 3 can move in the temporal part of the box body 1. The use of the sliding groove 41 and the slider 42 can play a role in limiting the movement of the adjusting box 3. The use of the threaded block 43 and the threaded sleeve 44 can play a role in fixing after the adjusting box 3 is adjusted to a suitable position. The opening of the open mouth 8 is convenient for placing the rat. The use of the movable plate 10 can seal the open mouth 8 at one end of the box body 1. A circular installation through hole similar to the drinking water bottle 6 is opened at one end of the adjusting box 3, and a rectangular installation through groove adapted to the food box 7 is also opened at one end of the adjusting box 3. Support legs are connected to the bottoms of the box body 1 and the adjusting box 3.

[0035] A fixing frame 5 is installed at one end of the adjusting box 3, and a drinking water bottle 6 is arranged inside the fixing frame 5.

[0036] A food box 7 is arranged at one end of the adjusting box 3 and on one side of the drinking water bottle 6.

[0037] An open mouth 8 is opened at one end of the box body 1, and a movable plate 10 is arranged inside the open mouth 8.

[0038] An installation through groove 9 adapted to the movable plate 10 is opened at one side of the top of the box body 1.

[0039] The working principle of a rat arthritis modeling auxiliary device provided by the present utility model is as follows:

[0040] During use, when adjusting the length between the box body 1 and the adjusting box 3, by pulling the adjusting box 3 to move outward from the box body 1, when the adjusting box 3 moves, it drives the slider 42 to move inside the sliding groove 41. After the adjusting box 3 is adjusted to a suitable position, the threaded sleeve 44 is threadedly connected and fixed to the threaded block 43 on the slider 42.

[0041] Compared with the related technology, a rat arthritis modeling auxiliary device provided by the present utility model has the following beneficial effects:

[0042] The present utility model provides an auxiliary device for modeling arthritis in rats. Inside the box body 1, the cooperation operation among the adjustment box 3, the sliding groove 41, the sliding block 42, the threaded block 43 and the threaded sleeve 44 can be carried out, and the length between the box body 1 and the adjustment box 3 can be adjusted according to the size of the rat, without the need to replace the box body 1 and the adjustment box 3, thereby increasing the convenience of rat breeding.

[0043] Second Embodiment

[0044] Please refer to Figure 5 and Figure 6 Based on an auxiliary device for modeling arthritis in rats provided in the first embodiment of the present application, the second embodiment of the present application proposes another auxiliary device for modeling arthritis in rats. The second embodiment is only a preferred manner of the first embodiment, and the implementation of the second embodiment will not affect the independent implementation of the first embodiment.

[0045] Specifically, the difference of an auxiliary device for modeling arthritis in rats provided in the second embodiment of the present application is that on the surface of the box body 1, a disassembly component 11 is provided. The disassembly component 11 includes a filter plate 111. On both sides of the top and bottom of the filter plate 111, fixing blocks 112 are connected. On the surface of the box body 1, fixing grooves 113 adapted to the fixing blocks 112 are opened.

[0046] A fixing bolt 114 is provided between the box body 1 and the fixing block 112.

[0047] On the surface of the box body 1, a rectangular installation through groove adapted to the filter plate 111 is opened. The use of the fixing blocks 112 and the fixing grooves 113 can play a positioning role when the filter plate 111 is installed on the surface of the box body 1. On the rear inner wall of the fixing groove 113, a fixing hole adapted to the fixing bolt 114 is opened.

[0048] The working principle of an auxiliary device for modeling arthritis in rats provided by the present utility model is as follows:

[0049] When cleaning the inside of the box body 1, first take out the fixing bolt 114 between the fixing block 112 and the box body 1. After the fixing bolt 114 is taken out, then pull the filter plate 111 to move outward from the box body 1. When the filter plate 111 is disassembled, the fixing block 112 is driven to separate from the fixing groove 113 on the surface of the box body 1. After the filter plate 111 is separated from the box body 1, the inside of the box body 1 can be cleaned.

[0050] Compared with the related art, an auxiliary device for modeling arthritis in rats provided by the present utility model has the following beneficial effects:

[0051] The utility model provides an auxiliary device for establishing a rat arthritis model. The surface of the box body 1 is provided with a disassembly component 11, which can play a role in ventilating the inside of the box body 1 and the adjustment box 3, and is also convenient for cleaning the inside of the box body 1.

[0052] The above are only the embodiments of the present utility model, and do not limit the patent scope of the present utility model accordingly. Any equivalent structure or equivalent process transformation made by using the content of the specification and drawings of the present utility model, or directly or indirectly applied to other related technical fields, shall be equally included in the patent protection scope of the present utility model.

Claims

1. An auxiliary device for establishing a rat arthritis model, characterized in that Including: A box body, on one side of the bottom of the inner wall of the box body, a running belt is provided; An adjustment box, which is arranged at one end inside the box body. A fixing component is arranged between the adjustment box and the box body. The fixing component includes a sliding groove, a slider is slidably connected inside the sliding groove, the slider is connected to the adjustment box, a threaded block is connected to the surface of the slider, and a threaded sleeve is threadedly connected to the surface of the threaded block.

2. The rat arthritis model establishment assisting device according to claim 1, wherein A fixing frame is installed at one end of the adjustment box, and a water bottle is arranged inside the fixing frame.

3. The rat arthritis model establishment assisting device according to claim 2, characterized in that, A food box is arranged at one end of the adjustment box and on one side of the water bottle.

4. The rat arthritis modeling assistance device according to claim 1, characterized in that, An opening is formed at one end of the box body, and a movable plate is arranged inside the opening.

5. The rat arthritis modeling assistance device according to claim 4, wherein An installation through groove adapted to the movable plate is formed on one side of the top of the box body.

6. The rat arthritis modeling assistance device according to claim 1, wherein, A disassembly component is arranged on the surface of the box body. The disassembly component includes a filter plate. Fixed blocks are connected to both sides of the top and bottom of the filter plate, and fixing grooves adapted to the fixed blocks are formed on the surface of the box body.

7. The rat arthritis model establishment assisting device according to claim 6, characterized in that, A fixing bolt is arranged between the box body and the fixed block.

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