Protective device for preparing L-prolinamide

Abstract

The utility model discloses a protective device for preparing L-prolinamide, which relates to the technical field of preparation of L-prolinamide and comprises a top cover cage, a dust monitoring unit and a side protective unit, the lower end of the top cover cage is a square frame body, and the upper end of the top cover cage is of a frustum-shaped hollow structure; the dust monitoring unit comprises a supporting column, a hydraulic cylinder, a chassis, a mounting frame, a dust monitoring head and a pumping and discharging pipeline. The device is provided with the reliable dust monitoring unit, when leakage of the L-prolinamide powder is found, the pumping and discharging device can be started in time to collect the L-prolinamide powder so as to prevent workers from inhaling the L-prolinamide powder to cause danger, and the L-prolinamide powder in airflow is separated and recycled at the tail end of the pumping and discharging pipeline, so that the labor intensity of workers is reduced, and the working efficiency is improved. And a reliable side face protection unit is further arranged, so that the protection effect can be achieved on the periphery of the production and storage equipment, and the leaked L-prolinamide powder is prevented from making direct contact with the skin and eyes of a worker.

Description

Technical Field

[0001] The utility model relates to the technical field of L - prolinamide preparation, in particular to a protective device for L - prolinamide preparation. Background Technique

[0002] L - Prolinamide is an important intermediate for synthesizing polypeptides and chiral drugs, and is also used as a chiral ligand in asymmetric catalytic synthesis reactions for Robinson cyclization reaction, Aldol reaction, etc. At the same time, it is also a raw material for health products. L - Prolinamide is a raw material for synthesizing vildagliptin for treating type 2 diabetes and anticancer drugs. In recent years, there have been many reports on its derivatives as chiral ligands for catalytic asymmetric synthesis. Due to its mild reaction conditions, metal - free, low - toxicity, atom - economy, enzyme - like catalysis and other characteristics, it has become an asymmetric synthesis method that has received much attention and developed rapidly in recent years. Therefore, the research and development of industrial synthesis of L - prolinamide has important practical significance;

[0003] L - Prolinamide is a white powdery solid, easy to absorb moisture, soluble in water, methanol, ethanol and other solvents, soluble at high temperature in ethyl acetate and slightly soluble at low temperature, and can be recrystallized with EA. Referring to the EC safety code table, the following safety precautions should be taken during the production of L - prolinamide: S22 Do not breathe dust; S24 / 25 Avoid contact with skin and eyes. Therefore, a protective device for L - prolinamide production and preparation is required in the corresponding production workshop. For this reason, we propose a protective device for L - prolinamide preparation. Content of the Utility Model

[0004] The technical problem to be solved by the utility model is to overcome the existing defects, and provide a protective device for L - prolinamide preparation, which has a reliable dust monitoring unit. When L - prolinamide powder leakage is detected, the exhaust device can be started in time to collect the L - prolinamide powder to prevent workers from inhaling and causing danger, and separate the L - prolinamide powder in the air flow at the end of the exhaust pipe for recycling the collected L - prolinamide powder. It also has a reliable side protection unit, which can play a protective role around the production and storage equipment to prevent the leaked L - prolinamide powder from directly contacting the skin and eyes of workers, and can effectively solve the problems in the background technique.

[0005] To achieve the above purpose, the utility model provides the following technical scheme: A protective device for L - prolinamide preparation, including a top cover cage, a dust monitoring unit and a side protection unit;

[0006] The lower end of the top cover cage is a square frame body, and its upper end is a hollow structure in the shape of a frustum of a cone;

[0007] Dust monitoring unit: It includes columns, hydraulic cylinders, a chassis, a mounting frame, a dust monitoring head, and an exhaust pipe. At the four corner positions at the lower end of the top cage, a vertical column is fixedly connected to each. Inside the lower end of each column, a hydraulic cylinder is embedded and installed. The telescopic end of the hydraulic cylinder extends downward, and its end is fixedly connected to the center position of the chassis. Inside the internal channel of the frustum-shaped structure of the top cage, a cross-shaped mounting frame is fixedly connected. At the lower end of the intersection position in the middle of the mounting frame, a dust monitoring head is installed. At the upper end of the frustum structure of the top cage, an exhaust pipe is communicated. The upper end of the exhaust pipe bends horizontally to the right;

[0008] Side protection unit: It is installed inside and below the top cage.

[0009] The top cage covers the L-prolinamide production and storage equipment. The exhaust pipe is used to exhaust the collected L-prolinamide powder outwards. The columns are used to support the top cage. The hydraulic cylinders are used to control the lifting of the top cage, so that the top cage comes to a position close to the upper part of the L-prolinamide production and storage equipment and covers the outside of the production and storage equipment. The mounting frame is used for the installation of the dust monitoring head. The dust monitoring head monitors the air dust in the space near the production and storage equipment. When it is found that the L-prolinamide powder leaks, the exhaust device is started in time to collect the L-prolinamide powder to prevent workers from inhaling and causing danger. The side protection unit is used to play a protective role around the production and storage equipment to prevent the leaked L-prolinamide powder from directly contacting the skin and eyes of workers.

[0010] Further, the dust monitoring unit further includes a mounting box, a motor, and an impeller. The mounting box is installed at the upper end of the top cage. The mounting box is communicated with the top cage and the exhaust pipe respectively. The motor is fixedly installed on the outer side of the front end of the mounting box. Inside the mounting box, an impeller is rotatably connected at a position biased to the right. The left half of the impeller is vertically corresponding to the internal channel communicated with the top cage and the exhaust pipe. The output shaft of the motor is fixedly connected to the rotating shaft of the impeller through a coupling. The mounting box is used for the installation of the motor. The motor drives the impeller to rotate, so as to form an outward flowing air current in the exhaust pipe, generating a suction force on the dust at the top cage.

[0011] Further, the side protection unit includes side sliding frames, glass baffles, and tightening blocks. On the opposite sides of every two columns, a vertical rod-shaped side sliding frame is fixedly connected. A vertical sliding groove is opened on the side of each side sliding frame close to the middle of the device. A vertical glass baffle is slidably connected between every two side sliding frames with corresponding openings. And two arc-shaped grooves are opened at the lower end of the glass baffle. The side sliding frames are used for the installation of the glass baffles. The internal sliding grooves enable the glass baffles to slide up and down. The grooves at the bottom facilitate lifting the glass baffles. By tightening the tightening blocks on both sides, the glass baffles can be fixed.

[0012] Furthermore, the side protection unit further includes distance sensors and a PLC controller. At the lower end of the frustum-shaped structure of the top cage and near the four corners, a distance sensor is embedded and installed at each position. The PLC controller is installed at the front end of the square section of the top cage. The distance sensors, the motor, the hydraulic cylinder, and the dust monitoring head are all bidirectionally electrically connected to the PLC controller, and the PLC controller is electrically connected to the output end of an external power supply. The distance sensors are used to detect the distance between the top cage and the top of the L-prolinamide production and storage equipment. The PLC controller automatically adjusts the position of the top cage according to the detected data to make the top cage at an appropriate height, and the PLC controller is used to cooperate with the dust monitoring head to jointly monitor and extract the leaked powder.

[0013] Furthermore, it further includes a support seat and a separation box. The support seat is fixedly connected to the lower position near the front end of the installation box, and the support seat supports the lower side of the motor. The horizontal end of the extraction pipeline facing right is fixedly connected to the separation box, and a dust filtering device is arranged inside the separation box. The support seat is used to support the motor, and the separation box is used to separate the extracted L-prolinamide powder from the air.

[0014] Furthermore, it further includes a one-way air valve and a collection tank. A one-way air valve is installed at the upper end of the separation box, and a collection tank is screwed and installed at the lower end of the separation box. The air extracted into the separation box is discharged outward along the one-way air valve, and the separated L-prolinamide powder falls downward into the collection tank. The collection tank can be rotated and removed to recycle the collected L-prolinamide powder.

[0015] Compared with the prior art, the beneficial effects of the present utility model are as follows: This protective device for L-prolinamide preparation has the following advantages:

[0016] 1. It has a reliable dust monitoring unit, which can start the extraction device in time to collect the L-prolinamide powder when it is found that the L-prolinamide powder leaks, so as to prevent workers from inhaling and causing danger, and separate the L-prolinamide powder in the air flow at the end of the extraction pipeline to recycle the collected L-prolinamide powder;

[0017] 2. It has a reliable side protection unit, which can play a protective role around the production and storage equipment to prevent the leaked L-prolinamide powder from directly contacting the skin and eyes of workers; and under the action of the distance sensors and the PLC controller, the position of the top cage can be automatically adjusted to make the top cage and the glass baffle at an appropriate height;

[0018] 3. The utility model has a reliable dust monitoring unit, which can start the exhaust device in time to collect L-prolinamide powder when L-prolinamide powder leakage is detected, so as to prevent workers from inhaling and causing danger, and separate the L-prolinamide powder in the air flow at the end of the exhaust pipeline to recycle the collected L-prolinamide powder. It also has a reliable side protection unit, which can play a protective role around the production and storage equipment to prevent the leaked L-prolinamide powder from directly contacting the skin and eyes of workers. Brief Description of the Drawings

[0019] Figure 1 is a schematic structural diagram of the utility model;

[0020] Figure 2 is a schematic structural diagram of the lower side of the utility model;

[0021] Figure 3 For the utility model Figure 2 is an enlarged view of the structure at A in the figure.

[0022] In the figure: 1 top cage, 2 dust monitoring unit, 21 support column, 22 hydraulic cylinder, 23 chassis, 24 mounting bracket, 25 dust monitoring head, 26 exhaust pipeline, 27 mounting box, 28 motor, 29 impeller, 3 side protection unit, 31 side sliding frame, 32 glass baffle, 33 tightening block, 34 distance sensor, 35 PLC controller, 4 one-way air valve, 5 supporting seat, 6 separation box, 7 collection tank. Detailed Description of the Preferred Embodiment

[0023] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0024] Please refer to Figures 1-3 , this embodiment provides a technical solution: a protective device for preparing L-prolinamide, including a top cage 1, a dust monitoring unit 2 and a side protection unit 3;

[0025] The lower end of the top cage 1 is a square frame body, and its upper end is a hollow structure in the shape of a frustum of a cone;

[0026] Dust monitoring unit 2: It includes a support column 21, a hydraulic cylinder 22, a chassis 23, a mounting bracket 24, a dust monitoring head 25 and an exhaust pipe 26. A vertical support column 21 is fixedly connected to each of the four corner positions at the lower end of the top cage 1. A hydraulic cylinder 22 is embedded and installed inside the lower end of each support column 21. The telescopic end of the hydraulic cylinder 22 extends downward and its end is fixedly connected to the center position of the chassis 23. A cross-shaped mounting bracket 24 is fixedly connected to the internal passage of the frustum-shaped structure of the top cage 1. The dust monitoring head 25 is installed at the lower end of the cross position in the middle of the mounting bracket 24. The exhaust pipe 26 is communicated with the upper end of the frustum structure of the top cage 1, and the upper end of the exhaust pipe 26 bends horizontally to the right;

[0027] Side protection unit 3: It is installed inside and below the top cage 1.

[0028] The top cage 1 covers the L-prolinamide production and storage equipment. The exhaust pipe 26 is used to exhaust the collected L-prolinamide powder outward. The support column 21 is used to support the top cage 1. The hydraulic cylinder 22 is used to control the lifting of the top cage 1, so that the top cage 1 comes to a position close to the upper part of the L-prolinamide production and storage equipment and covers the outside of the production and storage equipment. The mounting bracket 24 is used for the installation of the dust monitoring head 25. The dust monitoring head 25 monitors the air dust in the space near the production and storage equipment, so as to start the exhaust device in time to collect the L-prolinamide powder when it is found that the L-prolinamide powder leaks, so as to prevent workers from inhaling and causing danger. The side protection unit 3 is used to play a protective role around the production and storage equipment, so as to prevent the leaked L-prolinamide powder from directly contacting the skin and eyes of workers.

[0029] The dust monitoring unit 2 further includes an installation box 27, a motor 28 and an impeller 29. The installation box 27 is installed at the upper end of the top cage 1. The installation box 27 is communicated with the top cage 1 and the exhaust pipe 26 respectively. The motor 28 is fixedly installed on the outer side of the front end of the installation box 27. The impeller 29 is rotatably connected to the position on the right side inside the installation box 27. The left half of the impeller 29 corresponds vertically to the internal passage communicated with the top cage 1 and the exhaust pipe 26. The output shaft of the motor 28 is fixedly connected to the rotating shaft of the impeller 29 through a coupling. The installation box 27 is used for the installation of the motor 28. The motor 28 drives the impeller 29 to rotate, so as to form an outward flowing air current in the exhaust pipe 26, generating a suction force on the dust at the top cage 1.

[0030] The side protection unit 3 includes a side sliding frame 31, a glass baffle 32 and a tightening block 33. A vertical rod-shaped side sliding frame 31 is fixedly connected to the relative side of each two struts 21. A vertical chute is provided on the side of the side sliding frame 31 close to the middle of the device. A vertical glass baffle 32 is slidably connected between every two side sliding frames 31 corresponding to the openings, and two arc-shaped grooves are provided at the lower end of the glass baffle 32. The side sliding frame 31 is used for installing the glass baffle 32. The internal chute enables the glass baffle 32 to slide up and down. The grooves at the bottom facilitate lifting the glass baffle 32. By tightening the tightening blocks 33 on both sides, the glass baffle 32 can be fixed.

[0031] The side protection unit 3 further includes a distance sensor 34 and a PLC controller 35. A distance sensor 34 is embedded and installed at the lower end of the frustum-shaped structure of the top cage 1 and near the four corners. A PLC controller 35 is installed at the front end of the square section of the top cage 1. The distance sensor 34, the motor 28, the hydraulic cylinder 22 and the dust monitoring head 25 are all bidirectionally electrically connected to the PLC controller 35, and the PLC controller 35 is electrically connected to the output end of an external power supply. The distance sensor 34 is used to detect the distance between the top cage 1 and the top of the L-prolinamide production and storage equipment. The PLC controller 35 automatically adjusts the position of the top cage 1 according to the detected data to make the top cage 1 at an appropriate height, and the PLC controller 35 is used to cooperate with the dust monitoring head to jointly realize the monitoring and extraction of the leaked powder.

[0032] It further includes a supporting seat 5 and a separation box 6. A supporting seat 5 is fixedly connected to the lower front position of the installation box 27. The supporting seat 5 supports the lower side of the motor 28. The right horizontal end of the extraction pipe 26 is fixedly connected to a separation box 6, and a dust filtering device is arranged inside the separation box 6. The supporting seat 5 is used to support the motor 28, and the separation box 6 is used to separate the extracted L-prolinamide powder from the air.

[0033] It further includes a one-way air valve 4 and a collection tank 7. A one-way air valve 4 is installed at the upper end of the separation box 6, and a collection tank 7 is screwed and installed at the lower end of the separation box 6. The air extracted into the separation box 6 is discharged outward along the one-way air valve 4, and the separated L-prolinamide powder falls downward into the collection tank 7. The collection tank 7 can be unscrewed and removed to recycle the collected L-prolinamide powder.

[0034] The working principle of a protective device for the preparation of L-prolinamide provided by the utility model is as follows: This device has a reliable dust monitoring unit 2, which can start the exhaust device in time to collect the L-prolinamide powder when it detects the leakage of L-prolinamide powder, so as to prevent workers from inhaling and causing danger, and separate the L-prolinamide powder in the air flow at the end of the exhaust pipe 26 to recycle the collected L-prolinamide powder. The top cage 1 covers the L-prolinamide production and storage equipment. The exhaust pipe 26 is used to exhaust the collected L-prolinamide powder outwards. The support column 21 is used to support the top cage 1. The hydraulic cylinder 22 is used to control the lifting of the top cage 1, so that the top cage 1 comes to a position close to the top of the L-prolinamide production and storage equipment and covers the outside of the production and storage equipment. The mounting frame 24 is used for installing the dust monitoring head 25. The dust monitoring head 25 monitors the air dust in the space near the production and storage equipment, so as to start the exhaust device in time to collect the L-prolinamide powder when it detects the leakage of L-prolinamide powder, so as to prevent workers from inhaling and causing danger. The PLC controller is used to cooperate with the dust monitoring head to jointly realize the monitoring and exhaust of the leaked powder. The mounting box 27 is used for installing the motor 28. The motor 28 drives the impeller 29 to rotate, so as to form an outward flowing air flow in the exhaust pipe 26, generating a suction force on the dust at the top cage 1. The supporting seat 5 is used to support the motor 28. The separation box 6 is used to separate the exhausted L-prolinamide powder from the air. The air exhausted into the separation box 6 is discharged outwards along the one-way air valve 4. The separated L-prolinamide powder falls down into the collection tank 7. The collection tank 7 can be rotated and removed to recycle the collected L-prolinamide powder. This device also has a reliable side protection unit 3, which can play a protective role around the production and storage equipment to prevent the leaked L-prolinamide powder from directly contacting the skin and eyes of workers. The side sliding frame 31 is used for installing the glass baffle 32. The internal chute enables the glass baffle 32 to slide up and down. The groove at the bottom facilitates lifting the glass baffle 32. By tightening the tightening blocks 33 on both sides, the glass baffle 32 can be fixed. The distance sensor 34 is used to detect the distance between the top cage 1 and the top of the L-prolinamide production and storage equipment. The PLC controller 35 automatically adjusts the position of the top cage 1 according to the detected data, so that the top cage 1 is at an appropriate height.

[0035] It should be noted that the PLC controller 35 controls the distance sensor 34, the motor 28, the hydraulic cylinder 22 and the dust monitoring head 25 to work by using the commonly used methods in the prior art.

[0036] The above are only embodiments of the present utility model, and thus do not limit the patent scope of the present utility model. Any equivalent structure or equivalent process transformation made by using the content of the specification and drawings of the present utility model, or directly or indirectly applied in other related technical fields, shall similarly be included within the patent protection scope of the present utility model.

Claims

1. A protective device for the preparation of L-prolinamide, characterized in that: It includes a top cage (1), a dust monitoring unit (2) and a side protection unit (3); The lower end of the top cage (1) is a square frame, and its upper end is a hollow frustum-shaped structure; Dust monitoring unit (2): It includes a support column (21), a hydraulic cylinder (22), a chassis (23), a mounting bracket (24), a dust monitoring head (25) and an exhaust pipe (26). A vertical support column (21) is fixedly connected to each of the four corner positions at the lower end of the top cage (1). A hydraulic cylinder (22) is embedded and installed inside the lower end of each support column (21). The telescopic end of the hydraulic cylinder (22) extends downward and its end is fixedly connected to the center position of the chassis (23). A cross-shaped mounting bracket (24) is fixedly connected to the internal passage of the frustum-shaped structure of the top cage (1). A dust monitoring head (25) is installed at the lower end of the central cross position of the mounting bracket (24). An exhaust pipe (26) is communicated with the upper end frustum structure of the top cage (1), and the upper end of the exhaust pipe (26) bends horizontally to the right; Side protection unit (3): It is installed inside and below the top cage (1).

2. The protective device for preparing L-prolinamide according to claim 1, wherein: The dust monitoring unit (2) further includes a mounting box (27), a motor (28) and an impeller (29). A mounting box (27) is installed at the upper end of the top cage (1). The mounting box (27) is communicated with the top cage (1) and the exhaust pipe (26) respectively. A motor (28) is fixedly installed on the outer side of the front end of the mounting box (27). An impeller (29) is rotatably connected to a position on the right side inside the mounting box (27). The left half of the impeller (29) is vertically corresponding to the internal passage communicated with the top cage (1) and the exhaust pipe (26). The output shaft of the motor (28) is fixedly connected to the rotating shaft of the impeller (29) through a coupling.

3. The protective device for preparing L-prolinamide according to claim 2, wherein: The side protection unit (3) includes side sliding frames (31), glass baffles (32) and tightening blocks (33). A vertically rod-shaped side sliding frame (31) is fixedly connected to the relative side of each two support columns (21). Vertical sliding grooves are formed on the side of the side sliding frame (31) close to the middle of the device. A vertical glass baffle (32) is slidably connected between each two side sliding frames (31) with corresponding openings, and two arc-shaped grooves are formed at the lower end of the glass baffle (32).

4. A protective device for the preparation of L-prolinamide according to claim 3, characterized in that: The side protection unit (3) further includes a distance sensor (34) and a PLC controller (35). A distance sensor (34) is embedded and installed at the lower end of the frustum-shaped structure of the top cage (1) and close to the four corner positions. A PLC controller (35) is installed at the front end of the square section of the top cage (1). The distance sensor (34), the motor (28), the hydraulic cylinder (22) and the dust monitoring head (25) are all bidirectionally electrically connected to the PLC controller (35), and the PLC controller (35) is electrically connected to the output end of an external power supply.

5. The protective device for preparing L-prolinamide according to claim 3, characterized in that: It further includes a supporting base (5) and a separation box (6). A supporting base (5) is fixedly connected to the lower front position of the installation box (27). The supporting base (5) supports the lower side of the motor (28). The horizontal rightward end of the exhaust pipe (26) is fixedly connected to a separation box (6), and a dust filtering device is arranged inside the separation box (6).

6. The protective device for preparing L-prolinamide according to claim 5, wherein: It further includes a one-way air valve (4) and a collection tank (7). A one-way air valve (4) is installed at the upper end of the separation box (6), and a collection tank (7) is screwed and installed at the lower end of the separation box (6).

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