Explosion-proof device for stem cell cryopreservation tube

By designing a stem cell freezing tube explosion-proof device, the pressure components and rotating components automatically release pressure, the explosion problem of freezing tubes during resuscitation is solved and safety is improved.

CN223073098UActive Publication Date: 2025-07-08NOXIDARON (TIANJIN) BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422092519.9
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-27
Publication Date
2025-07-08
Estimated Expiration
2034-08-27

AI Technical Summary

Technical Problem

When the frozen storage tube is taken out of the liquid nitrogen tank and put into the water bath for heating and recovery, the liquid nitrogen rapidly gasifies and causes volume expansion, which cannot effectively release pressure, resulting in explosions and safety accidents.

Method used

A stem cell freezing storage tube explosion-proof device is designed, including a box, a placement block and a pressure component. It uses the circular block, round rod, ball and spring structure in the pressure component to automatically release pressure, and adjust the angle of the frozen storage tube by rotating the assembly to increase the surface area of liquid nitrogen to accelerate volatility.

Benefits of technology

Effectively avoid explosion of frozen storage ducts, improve safety, and reduce safety accidents through automatic discharge of pressure components and rotating components.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses an explosion-proof device for stem cell cryopreservation tubes, and particularly relates to the field of explosion-proof devices, the explosion-proof device comprises a box body and a placing block, the top of the box body is fixedly provided with a box cover, the inner surface of the placing block is movably provided with a plurality of cryopreservation tube bodies, the tops of the cryopreservation tube bodies are all provided with pressure assemblies, and the pressure assemblies are arranged on the box cover. By arranging the pressure assembly, when the pressure in the cryopreservation pipe body is increased, the interior of the cryopreservation pipe body is in high pressure, the high pressure can enter a first round rod through a first circular ring block, then a ball can be pushed, the ball moves upwards under the action of the pressure, and a first spring is in a compressed state; according to the cryopreservation tube, the round holes are formed in the cryopreservation tube body, so that the round balls cannot block the round holes, pressure can be discharged through the round holes, the situation that pressure in the cryopreservation tube body cannot be discharged can be avoided, meanwhile, automatic discharging is achieved, explosion of the cryopreservation tube body can be effectively avoided, safety is improved, and safety accidents are avoided.
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Description

Technical Field

[0001] The utility model relates to the technical field of explosion-proof devices, in particular to an explosion-proof device for a stem cell cryopreservation tube. Background Art

[0002] A cryopreservation tube is a container for storing strains (stem cells, tissues, DNA, RNA, etc.) in a laboratory, mainly used for the preservation or transfer of strains. Usually, during experiments, cryopreservation tubes may be used to store samples. For cryopreservation, the cryopreservation tube needs to be placed in a liquid nitrogen tank for long-term storage. When the strain needs to be revived, the cryopreservation tube is taken out of the liquid nitrogen and then put into a 37°C water bath. When the cryopreservation tube is taken out of the liquid nitrogen tank and put into the water bath for heating and revival, the liquid nitrogen in the tube quickly vaporizes, and the volume expands sharply, resulting in an explosion. To avoid the explosion of the cryopreservation tube, an explosion-proof device is needed. The cryopreservation tube is placed in the explosion-proof device, and then the explosion-proof device and the cryopreservation tube are put into the water bath. Wrapping the cryopreservation tube with an explosion-proof tube can inhibit the explosion of the cryopreservation tube.

[0003] The inventor found in daily work that when the cryopreservation tube is taken out of the liquid nitrogen tank and put into the water bath for heating and revival, the liquid nitrogen in the tube quickly vaporizes, and the volume expands sharply, resulting in an explosion. There is no effective pressure release, which will cause the cryopreservation tube to explode and lead to safety accidents due to the internal pressure.

[0004] In order to solve the problem of inconvenient installation and maintenance of electronic components, in the prior art, when the cryopreservation tube is taken out of the liquid nitrogen tank and put into the water bath for heating and revival, the liquid nitrogen in the tube quickly vaporizes, and the volume expands sharply, resulting in an explosion. There is no effective pressure release, which will cause the cryopreservation tube to explode and lead to safety accidents due to the internal pressure. Summary of the Utility Model

[0005] The purpose of the utility model is to solve the problem that during use, when the cryopreservation tube is taken out of the liquid nitrogen tank and put into the water bath for heating and revival, the liquid nitrogen in the tube quickly vaporizes, and the volume expands sharply, resulting in an explosion. There is no effective pressure release, which will cause the cryopreservation tube to explode and lead to safety accidents due to the internal pressure, and to propose a technology for an explosion-proof device for a stem cell cryopreservation tube.

[0006] To achieve the above object, the utility model adopts the following technical solution: An explosion-proof device for a stem cell cryopreservation tube, comprising a box body and a placement block. A box cover is fixedly installed on the top of the box body. A plurality of cryopreservation tube bodies are movably installed on the inner surface of the placement block. Pressure components are arranged on the tops of the plurality of cryopreservation tube bodies. Rotating components are symmetrically arranged on both sides of the placement block. The pressure component includes a first circular ring block fixedly connected to the top of the cryopreservation tube body. A threaded groove is opened on the inner wall of the first circular ring block. A first round rod is threadedly connected inside the threaded groove. A round hole is opened on the inner wall of the first round rod. A cross block is fixedly connected inside the round hole. A first spring is fixedly connected to one side of the cross block. One end of the first spring is fixedly connected to a spherical ball.

[0007] The effect achieved by the above components is that when the pressure inside the cryopreservation tube body becomes large and the inside is under high pressure, it will enter the first round rod through the first circular ring block, and then can push the spherical ball, causing the spherical ball to move upward under the action of the pressure, and making the first spring and the spherical ball in a compressed state. Furthermore, the spherical ball cannot block the round hole, and the pressure will be discharged through the round hole. Thus, it can avoid the situation that the pressure inside the cryopreservation tube body cannot be discharged, and at the same time achieve automatic discharge, and effectively avoid the explosion of the cryopreservation tube body, improve safety and prevent safety accidents from occurring.

[0008] Preferably, the inner diameter of the inner wall of the round hole gradually increases from bottom to top, and the minimum inner diameter of the inner wall of the round hole is smaller than the outer surface diameter of the spherical ball.

[0009] The effect achieved by the above components is that by setting the round hole, when the spherical ball is not under the action of pressure, it can pass through the first spring and closely adhere to the inner wall of the round hole for sealing. Under high pressure, it can move upward to open the round hole.

[0010] Preferably, a telescopic rod is arranged inside the first spring, and both ends of the telescopic rod are fixedly connected to the outer surface of the spherical ball and one side of the cross block respectively.

[0011] The effect achieved by the above components is that by setting the telescopic rod, when the first spring is compressed, it can prevent the first spring from undergoing compressive deformation, and thus can improve the service life of the first spring.

[0012] Preferably, a corrugated pipe is fixedly connected to the top of the first round rod. Communication holes are linearly and equidistantly distributed on the top of the box cover, and the corrugated pipe is rotationally connected to the communication holes.

[0013] The effect achieved by the above components is that by setting the corrugated pipe and the communication holes, when the placement block is rotated later, the corrugated pipe can still be fixed in the box cover to avoid the inability to release the internal pressure.

[0014] Preferably, a second circular ring block is fixedly connected to the outer surface of the corrugated pipe, and the outer surface diameter of the second circular ring block is larger than the inner wall diameter of the communication hole.

[0015] The effect achieved by the above components is that by setting the second circular ring block, when taking the cryopreservation tube body, the second circular ring block can limit the corrugated pipe during the rotation process, avoiding the corrugated pipe from falling off.

[0016] Preferably, the rotating assembly includes a second round rod fixedly connected to one side of the placing block. The second round rod is rotatably connected to the box body. One end of the second round rod is fixedly connected to a disc, and a round block is fixedly connected to one side of the box body.

[0017] The effect achieved by the above components is that by setting the rotating assembly, the rotation of the disc drives the second round rod to rotate, and then the placing block can be driven to rotate, so that the angle of the cryopreservation tube body placed in the placing block can change. When the liquid nitrogen container is placed obliquely, the surface area of the liquid nitrogen will relatively increase because the liquid will spread along the inclined surface of the container. The increased surface area means that more liquid nitrogen can simultaneously exchange heat with the surrounding air, thereby accelerating the volatilization of the liquid nitrogen and reducing the internal pressure.

[0018] Preferably, a circular groove is opened on one side of the round block, a dovetail slide bar is fixedly connected to the inner wall of the circular groove, and a clamping arc surface block is fixedly connected to one end of the dovetail slide bar.

[0019] The effect achieved by the above components is that by setting the dovetail slide bar and the clamping arc surface block, the clamping arc surface block can slide on the outer surface of the dovetail slide bar and cooperate with the movement of other components.

[0020] Preferably, a second spring is sleeved on the outer surface of the dovetail slide bar. The two ends of the second spring are respectively fixedly connected to one side of the clamping arc surface block and the inner wall of the circular groove. A plurality of clamping holes adapted to the size and shape of the outer surface of the clamping arc surface block are annularly distributed on one side of the disc.

[0021] The effect achieved by the above components is that by setting the clamping holes and the second spring, the clamping arc surface block can be under the compression reaction force of the second spring, so that the clamping arc surface block is clamped into the inner wall of the clamping hole, and then the fixed operation is carried out on the rotated angle.

[0022] In summary, the beneficial effects of the present utility model are:

[0023] 1. By setting a pressure component, when the pressure inside the cryogenic tube body increases, the interior is under high pressure, and it will enter the first round rod through the first circular ring block, and then push the ball, so that it moves upward under the action of the pressure of the ball, and makes the first spring and in a compressed state, so that the ball cannot block the circular hole, so that the pressure will be discharged through the circular hole, thereby preventing the pressure inside the cryogenic tube body from being unable to be discharged, and realizing automatic discharge at the same time, thereby effectively preventing the explosion of the cryogenic tube body, improving safety and avoiding safety accidents.

[0024] 2. By providing a rotating assembly, the rotation of the disc drives the second round rod to rotate, and then drives the placement block to rotate, so that the angle of the cryotube body placed in the placement block can change. When the liquid nitrogen container is tilted, the surface area of ​​the liquid nitrogen will increase relatively, because the liquid will spread along the inclined surface of the container. The increased surface area means that more liquid nitrogen can exchange heat with the surrounding air at the same time, thereby accelerating the volatilization of liquid nitrogen and reducing the internal pressure. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 It is a three-dimensional cross-sectional structural schematic diagram of the utility model;

[0026] Figure 2 It is a schematic diagram of the cross-sectional structure of the utility model as a whole;

[0027] Figure 3 This is a schematic diagram of the explosion structure of the pressure component of the utility model;

[0028] Figure 4 It is a schematic diagram of the cross-sectional structure of the circular hole of the utility model;

[0029] Figure 5 It is a schematic diagram of the exploded structure of the rotating assembly of the utility model;

[0030] Legend: 1. Box body; 2. Box cover; 3. Placement block; 4. Cryotube body; 5. Pressure assembly; 51. First circular ring block; 52. Threaded groove; 53. First round rod; 54. Round hole; 55. Cross block; 56. First spring; 57. Round ball; 58. Telescopic rod; 59. Bellows; 510. Second circular ring block; 511. Connecting hole; 6. Rotating assembly; 61. Second round rod; 62. Disc; 63. Round block; 64. Circular groove; 65. Dovetail slide rod; 66. Second spring; 67. Positioning arc block; 68. Positioning hole. DETAILED DESCRIPTION

[0031] Embodiment 1, as Figures 1-5As shown in the figure, the present utility model provides a technical solution: an explosion-proof device for a stem cell cryopreservation tube, which includes a box body 1 and a placement block 3. A box cover 2 is fixedly installed on the top of the box body 1. A number of cryopreservation tube bodies 4 are movably installed on the inner surface of the placement block 3. Pressure components 5 are provided on the tops of the plurality of cryopreservation tube bodies 4. Rotating components 6 are symmetrically arranged on both sides of the placement block 3.

[0032] During use, the cryopreservation tube body 4 is placed into the placement block 3. At this time, sealing operation is performed on it through the pressure component 5. When the pressure inside the cryopreservation tube body 4 is large, automatic discharge will occur. At the same time, the placement angle of the cryopreservation tube body 4 can be adjusted through the rotating component 6.

[0033] Refer to Figure 3 and Figure 4As shown in the figure, in this embodiment: The pressure component 5 includes a first circular ring block 51 fixedly connected to the top of the cryotube body 4. A threaded groove 52 is provided on the inner wall of the first circular ring block 51. A first round rod 53 is threadedly connected inside the threaded groove 52. A circular hole 54 is provided on the inner wall of the first round rod 53. A cross block 55 is fixedly connected inside the circular hole 54. A first spring 56 is fixedly connected to one side of the cross block 55. One end of the first spring 56 is fixedly connected to a spherical ball 57. By providing the pressure component 5, when the pressure inside the cryotube body 4 becomes large and the inside is under high pressure, it will enter the first round rod 53 through the first circular ring block 51, and then can push the spherical ball 57, causing the spherical ball 57 to move upward under the action of the pressure, and making the first spring 56 in a compressed state. As a result, the spherical ball 57 cannot block the circular hole 54, and the pressure will be discharged through the circular hole 54. This can avoid the pressure inside the cryotube body 4 from not being discharged, and at the same time achieve automatic discharge, thereby effectively avoiding the explosion of the cryotube body 4, improving safety and preventing safety accidents. The inner wall diameter of the circular hole 54 gradually increases from bottom to top, and the minimum inner wall diameter of the circular hole 54 is smaller than the outer surface diameter of the spherical ball 57. By providing the circular hole 54, the spherical ball 57 can be in close contact with the inner wall of the circular hole 54 for sealing through the first spring 56 when not under pressure, and can move upward under high pressure to open the circular hole 54. A telescopic rod 58 is provided inside the first spring 56. The two ends of the telescopic rod 58 are respectively fixedly connected to the outer surface of the spherical ball 57 and one side of the cross block 55. By providing the telescopic rod 58, when the first spring 56 is compressed, the first spring 56 can be prevented from undergoing compressive deformation, thereby improving the service life of the first spring 56. The top of the first round rod 53 is fixedly connected to a corrugated pipe 59. Communication holes 511 are linearly and equidistantly distributed on the top of the box cover 2. The corrugated pipe 59 is rotatably connected to the communication holes 511. By providing the corrugated pipe 59 and the communication holes 511, when the placement block 3 is rotated later, the corrugated pipe 59 can still be fixed in the box cover 2 to avoid the internal pressure from not being released. A second circular ring block 510 is fixedly connected to the outer surface of the corrugated pipe 59. The outer surface diameter of the second circular ring block 510 is larger than the inner wall diameter of the communication holes 511. By providing the second circular ring block 510, when taking the cryotube body 4, the second circular ring block 510 can limit the corrugated pipe 59 during the rotation process to avoid the corrugated pipe 59 from falling off.

[0034] Referring to Figure 5As shown in the figure, in this embodiment: The rotating assembly 6 includes a second round rod 61 fixedly connected to one side of the placing block 3. The second round rod 61 is rotatably connected to the box body 1. One end of the second round rod 61 is fixedly connected with a disc 62. One side of the box body 1 is fixedly connected with a round block 63. By providing the rotating assembly 6, the rotation of the disc 62 drives the second round rod 61 to rotate, and then the placing block 3 can be driven to rotate, so that the angle of the cryopreservation tube body 4 placed in the placing block 3 can change. When the liquid nitrogen container is placed obliquely, the surface area of the liquid nitrogen will relatively increase because the liquid will spread along the inclined surface of the container. The increased surface area means that more liquid nitrogen can simultaneously exchange heat with the surrounding air, thus accelerating the volatilization of the liquid nitrogen and reducing the internal pressure. One side of the round block 63 is provided with a circular groove 64. The inner wall of the circular groove 64 is fixedly connected with a dovetail slide bar 65. One end of the dovetail slide bar 65 is fixedly connected with a clamping arc surface block 67. By providing the dovetail slide bar 65 and the clamping arc surface block 67, the clamping arc surface block 67 can slide on the outer surface of the dovetail slide bar 65 to cooperate with the movement of other components. A second spring 66 is sleeved on the outer surface of the dovetail slide bar 65. The two ends of the second spring 66 are respectively fixedly connected with one side of the clamping arc surface block 67 and the inner wall of the circular groove 64. A plurality of clamping holes 68 which are adapted to the size and shape of the outer surface of the clamping arc surface block 67 are annularly distributed on one side of the disc 62. By providing the clamping holes 68 and the second spring 66, the clamping arc surface block 67 can be made to be inserted into the inner wall of the clamping hole 68 under the compression reaction of the second spring 66, so as to fix the rotated angle.

[0035] Working principle: When in use, rotate the first round rod 53 so that the first round rod 53 is threadedly connected to the first ring block 51. When the internal pressure of the cryopreservation tube body 4 increases and is in a high-pressure state at this time, it will enter the first round rod 53 through the first ring block 51, and then the spherical ball 57 can be pushed, so that the spherical ball 57 moves upward under the action of the pressure, and the first spring 56 is in a compressed state. Then the spherical ball 57 cannot block the round hole 54, so that the pressure can be discharged through the round hole 54, thus avoiding the inability to discharge the internal pressure of the cryopreservation tube body 4 and realizing automatic discharge. Secondly, the clamping arc surface block 67 can be pressed, so that the clamping arc surface block 67 squeezes the second spring 66 and slides on the dovetail end of the dovetail slide bar 65, so that the clamping arc surface block 67 moves away from the clamping hole 68. At this time, rotate the disc 62 to drive the second round rod 61 to rotate, and then drive the cryopreservation tube body 4 placed in the placing block 3 to adjust the angle. When the angle is adjusted to the appropriate angle, release the clamping arc surface block 67, so that the clamping arc surface block 67 is inserted into the clamping hole 68 under the action of the second spring 66 for fixing operation.

[0036] In the description of the present utility model, it should be noted that unless otherwise clearly specified and defined, the terms "installed", "connected", and "coupled" shall be understood in a broad sense. For example, it may be a fixed connection, a detachable connection, or an integral connection; it may be a mechanical connection or an electrical connection; it may be directly connected or indirectly connected through an intermediate medium, and it may be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood through specific circumstances.

Claims

1. An explosion-proof device for a stem cell cryopreservation tube, comprising a box body (1) and a placement block (3), characterized in that: A box cover (2) is fixedly installed on the top of the box body (1). A number of cryotube bodies (4) are movably installed on the inner surface of the placement block (3). Pressure assemblies (5) are arranged on the tops of the cryotube bodies (4). Rotating assemblies (6) are symmetrically arranged on both sides of the placement block (3). The pressure assembly (5) includes a first circular ring block (51) fixedly connected to the top of the cryotube body (4). A threaded groove (52) is formed in the inner wall of the first circular ring block (51). A first round rod (53) is threadedly connected inside the threaded groove (52). A round hole (54) is formed in the inner wall of the first round rod (53). A cross block (55) is fixedly connected inside the round hole (54). A first spring (56) is fixedly connected to one side of the cross block (55). One end of the first spring (56) is fixedly connected to a spherical ball (57).

2. The explosion-proof device for a stem cell cryopreservation tube according to claim 1, wherein: The inner wall diameter of the round hole (54) gradually increases from bottom to top, and the minimum inner wall diameter of the round hole (54) is smaller than the outer surface diameter of the spherical ball (57).

3. The explosion-proof device for a stem cell cryopreservation tube according to claim 1, wherein: A telescopic rod (58) is arranged inside the first spring (56). The two ends of the telescopic rod (58) are respectively fixedly connected to the outer surface of the spherical ball (57) and one side of the cross block (55).

4. The explosion-proof device for a stem cell cryopreservation tube according to claim 1, wherein: A corrugated pipe (59) is fixedly connected to the top of the first round rod (53). Communication holes (511) are linearly and equidistantly distributed on the top of the box cover (2). The corrugated pipe (59) is rotatably connected to the communication holes (511).

5. The explosion-proof device for a stem cell cryopreservation tube according to claim 4, wherein: A second circular ring block (510) is fixedly connected to the outer surface of the corrugated pipe (59). The outer surface diameter of the second circular ring block (510) is larger than the inner wall diameter of the communication hole (511).

6. The explosion-proof device for stem cell cryopreservation tubes according to claim 1, wherein: The rotating assembly (6) includes a second round rod (61) fixedly connected to one side of the placement block (3). The second round rod (61) is rotatably connected to the box body (1). A disc (62) is fixedly connected to one end of the second round rod (61). A round block (63) is fixedly connected to one side of the box body (1).

7. The explosion-proof device for stem cell cryopreservation tubes according to claim 6, wherein: A circular groove (64) is formed on one side of the round block (63). A dovetail slide bar (65) is fixedly connected to the inner wall of the circular groove (64). A clamping arc surface block (67) is fixedly connected to one end of the dovetail slide bar (65).

8. The explosion-proof device for a stem cell cryopreservation tube according to claim 7, wherein: A second spring (66) is sleeved on the outer surface of the dovetail slide bar (65). The two ends of the second spring (66) are respectively fixedly connected to one side of the clamping arc surface block (67) and the inner wall of the circular groove (64). A number of clamping holes (68) that are adapted in size and shape to the outer surface of the clamping arc surface block (67) are annularly distributed on one side of the disc (62).