Nucleic acid extraction kit capable of preventing liquid leakage

The nucleic acid extraction kit addresses the issue of reagent leakage by using a collection system to contain and identify leaks, reducing contamination and simplifying cleanup.

CN223101360UActive Publication Date: 2025-07-15JILIN HUANJI BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202422258284.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-14
Publication Date
2025-07-15
Estimated Expiration
2034-09-14

AI Technical Summary

Technical Problem

Traditional nucleic acid extraction kits lack effective monitoring mechanisms, which makes it difficult to detect and deal with reagent bottles in a timely manner after leakage, which may contaminate other reagents.

Method used

A leak-proof nucleic acid extraction reagent kit is designed, which includes a box body and a box lid, and is equipped with a reagent plate and a collection chamber. The bottom of the reagent tank is connected to the collection hole. The liquid of the broken reagent bottle flows into the collection chamber and is collected through the collection chamber. A magnetic suction plate is set to ensure the accurate positioning of the collection chamber, and the marking grid helps quickly locate the broken reagent tank.

Benefits of technology

It effectively avoids contamination of other reagents when the reagent bottle is damaged, facilitates staff to deal with leaked reagents, and improves the safety and management efficiency of reagent storage.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of reagent storage, in particular to a leakage-proof nucleic acid extraction kit. The box comprises a box body and a box cover, a reagent plate is arranged in the kit body, a plurality of reagent grooves for placing reagents are uniformly formed in the reagent plate, a collecting cavity is formed between the lower end face of the reagent plate and the bottom wall of the inner side of the kit body, and collecting holes communicated with the collecting cavity are formed in the bottoms of the reagent grooves. A collecting drawer is arranged in the collecting cavity, and a mounting hole for the collecting drawer to enter and exit from the collecting cavity is formed in the side wall of the box body. During use, a reagent bottle is placed in the reagent groove, when the reagent bottle is damaged, leaked liquid can flow into the collection drawer of the collection cavity through the collection hole, and a worker can judge whether the reagent leaks or not according to whether the liquid exists in the collection drawer or not, so that the phenomenon that the reagent leaks or not when the worker picks up the damaged reagent bottle is avoided. The reagent bottle can be widely applied to the technical field of reagent storage.
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Description

Technical Field

[0001] The utility model relates to the technical field of reagent storage, and more specifically, to a nucleic acid extraction kit with anti-leakage function. Background Art

[0002] In nucleic acid extraction work, the accurate use and preservation of reagents are crucial. However, there is a significant problem with the current traditional nucleic acid extraction kits, that is, it is difficult to directly detect when the reagent bottles stored in them leak.

[0003] Traditional nucleic acid extraction kits usually have a relatively simple structure and lack an effective monitoring mechanism for reagent storage. Due to the absence of obvious indication or warning systems, it is difficult for staff to determine whether the reagent bottles in the kit are damaged and leaking without taking the reagent bottles out of the kit. When the staff picks up a damaged reagent bottle without any additional protective measures, the reagent leaked from the damaged reagent bottle may contaminate other reagents in the kit. Summary of the Utility Model

[0004] Aiming at the problem that traditional nucleic acid extraction kits in the prior art usually have a relatively simple structure and lack an effective monitoring mechanism for reagent storage, the utility model provides a nucleic acid extraction kit with anti-leakage function.

[0005] To solve the above technical problems, the utility model is solved by the following technical solutions:

[0006] A nucleic acid extraction kit with anti-leakage function, which includes a box body and a box cover; a reagent plate is arranged in the box body, and a plurality of reagent grooves for placing reagents are evenly arranged on the reagent plate. A collection cavity is arranged between the lower end surface of the reagent plate and the inner bottom wall of the box body, and a collection hole communicating with the collection cavity is arranged at the bottom of the reagent groove.

[0007] The reagent bottles are respectively stored in the respective reagent grooves on the reagent plate, which can avoid the contamination of other reagent bottles when a certain reagent bottle is damaged and leaks; the collection hole can enable the reagent flowing out of the damaged reagent bottle to flow into the collection cavity. On the one hand, it can reduce the reagent attached to the reagent bottle body, which is convenient for the staff to handle. On the other hand, the staff can judge whether the reagent bottle is damaged and leaking by observing whether there is reagent in the collection cavity.

[0008] Preferably, a collection drawer is arranged in the collection cavity, and an installation hole for the collection drawer to enter and exit the collection cavity is arranged on the side wall of the box body.

[0009] By arranging a collection drawer in the collection cavity, the liquid discharged through the collection hole is collected into the collection drawer, which is convenient for the staff to handle.

[0010] Preferably, an installation plate is fixedly arranged in the collection drawer, the upper end surface of the installation plate is attached to the lower end surface of the reagent plate, and waste liquid grooves corresponding to the reagent grooves one by one are formed on the upper end surface of the installation plate.

[0011] By attaching the upper end surface of the installation plate to the lower end surface of the reagent plate, the waste liquid discharged from the reagent groove only enters the waste liquid groove directly below the reagent groove. After the staff pulls out the installation drawer, they can find the position of the waste liquid groove with waste liquid inside, so as to determine the position of the reagent groove where the damaged reagent bottle is located.

[0012] Preferably, a plurality of horizontally arranged first horizontal grooves are evenly distributed on the upper end surface of the installation plate, and a plurality of vertically arranged first vertical grooves are evenly distributed on the upper end surface of the installation plate. The first horizontal grooves and the first vertical grooves intersect with each other to form a plurality of first grids, and at most one waste liquid groove is arranged in each first grid.

[0013] In order to increase the quantity of reagent bottles stored in the reagent kit, the distance between each reagent groove is often relatively close, and correspondingly, the distance between each waste liquid groove is also relatively close. In order to enable the staff to simply judge the position of the reagent groove storing waste liquid, a first vertical groove and a first horizontal groove are arranged on the upper end surface of the installation plate to form a first grid, and each waste liquid groove is respectively designed in each first grid.

[0014] Preferably, first marking grids corresponding to the first grids one by one are arranged on the upper end surface of the collection drawer, and numbers are sequentially engraved on each first marking grid.

[0015] In order to enable the staff to better confirm the position of the waste liquid groove storing waste liquid, first marking grids corresponding to the first grids are arranged on the upper end surface of the collection drawer. The number of first marking grids in the horizontal position is the same as the number of first grids on the installation plate in the horizontal direction, and the number of first marking grids in the vertical position is the same as the number of first grids on the installation plate in the vertical direction. Each marking grid is sequentially numbered. Through the above design, the staff can quickly judge the row and column where the waste liquid groove storing waste liquid is located.

[0016] Preferably, a plurality of horizontally arranged second horizontal grooves are evenly distributed on the upper end surface of the reagent plate, and a plurality of vertically arranged second vertical grooves are evenly distributed on the upper end surface of the reagent plate. The second horizontal grooves and the second vertical grooves intersect with each other to form a plurality of second grids, and at most one reagent groove is arranged in each second grid. Second marking grids corresponding to the second grids one by one are arranged at the edge of the upper end surface of the reagent plate, and numbers are sequentially engraved on each second marking grid.

[0017] The number of the second marking cells in the horizontal position is consistent with the number of the second grids of the reagent plate in the horizontal direction, and the number of the second marking cells in the vertical position is consistent with the number of the first grids of the reagent plate in the vertical direction. After the staff determines the row and column where the waste liquid tank storing the waste liquid is located through the first marking cells, they can quickly find the reagent tank where the damaged reagent bottle is located through the second marking cells, and then proceed with the next step of processing.

[0018] Preferably, a first magnetic attraction plate is provided on the side wall of the collection cavity far from the mounting hole, and a second magnetic attraction plate matching with the first magnetic attraction plate is provided on the side wall of the collection drawer.

[0019] Through the arrangement of the first magnetic attraction plate and the second magnetic attraction plate, the installation of the collection drawer in the collection cavity is preferably realized through the magnetic force between the first magnetic attraction plate and the second magnetic attraction plate, avoiding the dislocation of the collection drawer during the use of the reagent kit. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the overall structure of the reagent kit in the embodiment;

[0021] Figure 2 It is a schematic diagram of the structure of the reagent kit at the cross-section in the embodiment;

[0022] Figure 3 It is a schematic diagram of the structure of the collection drawer and the mounting plate;

[0023] Figure 4 It is a schematic diagram of the structure of the mounting plate;

[0024] Figure 5 It is a schematic diagram of the structure of the collection drawer.

[0025] The names of the parts referred to by each numerical label in the drawings are as follows:

[0026] 110, box body; 1101, collection cavity; 1102, mounting hole; 1103, first magnetic attraction plate; 120, box cover; 130, reagent plate; 1301, reagent tank; 1302, collection hole; 1303, second horizontal groove; 1304, second vertical groove; 1305, second grid; 1306, second marking cell; 140, collection drawer; 1401, first marking cell; 1402, second magnetic attraction plate; 1403, handle; 150, mounting plate; 1501, waste liquid tank; 1502, first horizontal groove; 1503, first vertical groove; 1504, first grid. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0027] To further understand the content of the present invention, the present invention will be described in detail with reference to the drawings and embodiments. It should be understood that the embodiments are only for explaining the present invention rather than limiting it.

[0028] Embodiment

[0029] As shown in Figure 1-2 FIG. 5, a nucleic acid extraction kit with anti-liquid leakage includes a box body 110 and a box cover 120; a reagent plate 130 is provided in the box body 110, and a plurality of reagent grooves 1301 for placing reagents are evenly provided on the reagent plate 130. A collection cavity 1101 is provided between the lower end surface of the reagent plate 130 and the inner bottom wall of the box body 110, and a collection hole 1302 communicating with the collection cavity 1101 is provided at the bottom of the reagent groove 1301. A collection drawer 140 is provided in the collection cavity 1101, an installation hole 1102 for the collection drawer 140 to enter and exit the collection cavity 1101 is provided on the side wall of the box body 110, and a handle 1403 is provided on the collection drawer 140; a first magnetic attraction plate 1103 is provided on the side wall of the collection cavity 1101 far from the installation hole 1102, and a second magnetic attraction plate 1402 matching with the first magnetic attraction plate 1103 is provided on the side wall of the collection drawer 140.

[0030] The reagent bottles are respectively stored in the respective reagent grooves 1301 on the reagent plate 130, which can avoid the contamination of other reagent bottles when a certain reagent bottle is damaged and leaks; the collection hole 1302 can enable the reagent flowing out of the damaged reagent bottle to flow into the collection cavity 1101. On the one hand, it can reduce the reagent attached to the bottle body of the reagent bottle, which is convenient for the staff to handle. On the other hand, the staff can judge whether the reagent bottle is damaged and leaked by observing whether there is reagent in the collection drawer 140 in the collection cavity 1101. The liquid discharged through the collection hole 1302 is collected into the collection drawer 140, which is convenient for the staff to handle.

[0031] Among them, through the setting of the first magnetic attraction plate 1103 and the second magnetic attraction plate 1402, the installation of the collection drawer 140 in the collection cavity 1101 is preferably realized by the magnetic force between the first magnetic attraction plate 1103 and the second magnetic attraction plate 1402, and the dislocation of the collection drawer 140 during the use of the kit is avoided.

[0032] As shown in Figure 3-5 An installation plate 150 is fixedly provided in the collection drawer 140, the upper end surface of the installation plate 150 is attached to the lower end surface of the reagent plate 130, and waste liquid grooves 1501 corresponding to the reagent grooves 1301 one by one are provided on the upper end surface of the installation plate 150. A plurality of horizontally arranged first horizontal grooves 1502 are evenly distributed on the upper end surface of the installation plate 150, and a plurality of vertically arranged first vertical grooves 1503 are evenly distributed on the upper end surface of the installation plate 150. The first horizontal grooves 1502 and the first vertical grooves 1503 intersect with each other to form a plurality of first grids 1504, and at most one waste liquid groove 1501 is arranged in each first grid 1504. The collection drawer 140 is provided with first marking grids 1401 corresponding to the first grids 1504 one by one on its upper end surface, and numbers are engraved on each first marking grid 1401 in sequence.

[0033] By fitting the upper end face of the mounting plate 150 to the lower end face of the reagent plate 130, the waste liquid discharged from the reagent tank 1301 only enters the waste liquid tank 1501 directly below the reagent tank 1301. After the staff pulls out the mounting drawer, they can find the position of the waste liquid tank 1501 with waste liquid inside, so as to determine the position of the reagent tank 1301 where the broken reagent bottle is located.

[0034] In order to increase the number of reagent bottles stored in the reagent kit, the distance between each reagent tank 1301 is often relatively close, and correspondingly, the distance between each waste liquid tank 1501 is also relatively close. To enable the staff to simply judge the position of the reagent tank 1301 storing waste liquid, a first longitudinal groove 1503 and a first transverse groove 1502 are provided on the upper end face of the mounting plate 150 to form a first grid 1504, and each waste liquid tank 1501 is respectively designed within each first grid 1504.

[0035] To enable the staff to better confirm the position of the waste liquid tank 1501 storing waste liquid, a first marking grid 1401 corresponding to the first grid 1504 is provided on the upper end face of the collection drawer 140. The number of the first marking grids 1401 in the horizontal position is the same as the number of the first grids 1504 on the mounting plate 150 in the horizontal direction, and the number of the first marking grids 1401 in the vertical position is the same as the number of the first grids 1504 on the mounting plate 150 in the vertical direction. Each marking grid is sequentially numbered. Through the above design, the staff can quickly judge the row and column where the waste liquid tank 1501 storing waste liquid is located.

[0036] A plurality of horizontally arranged second transverse grooves 1303 are evenly distributed on the upper end face of the reagent plate 130, and a plurality of vertically arranged second longitudinal grooves 1304 are evenly distributed on the upper end face of the reagent plate 130. The second transverse grooves 1303 and the second longitudinal grooves 1304 intersect with each other to form a plurality of second grids 1305. At most one reagent tank 1301 is arranged within each second grid 1305. Second marking grids 1306 corresponding to the second grids 1305 one by one are provided at the edge of the upper end face of the reagent plate 130, and numbers are sequentially engraved on each second marking grid 1306.

[0037] The number of the second marking grids 1306 in the horizontal position is the same as the number of the second grids 1305 on the reagent plate 130 in the horizontal direction, and the number of the second marking grids 1306 in the vertical position is the same as the number of the first grids 1504 on the reagent plate 130 in the vertical direction. After the staff judges the row and column where the waste liquid tank 1501 storing waste liquid is located through the first marking grid 1401, they can quickly find the reagent tank 1301 where the broken reagent bottle is located through the second marking grid 1306, and then carry out the next step of processing.

[0038] In summary, the above are only the preferred embodiments of this embodiment. All equivalent changes and modifications made according to the scope of the patent application of this embodiment shall fall within the scope covered by the patent of this embodiment.

Claims

1. A nucleic acid extraction kit for preventing liquid leakage, comprising a box body (110) and a box cover (120); characterized in that: A reagent plate (130) is provided inside the box body (110). A plurality of reagent grooves (1301) for placing reagents are evenly arranged on the reagent plate (130). A collection cavity (1101) is provided between the lower end surface of the reagent plate (130) and the inner bottom wall of the box body (110). Collection holes (1302) communicating with the collection cavity (1101) are provided at the bottom of the reagent grooves (1301).

2. The nucleic acid extraction kit for preventing liquid leakage according to claim 1, characterized in that: A collection drawer (140) is provided inside the collection cavity (1101). An installation hole (1102) for the collection drawer (140) to enter and exit the collection cavity (1101) is provided on the side wall of the box body (110).

3. The nucleic acid extraction kit for preventing liquid leakage according to claim 2, wherein: An installation plate (150) is fixedly provided inside the collection drawer (140). The upper end surface of the installation plate (150) is attached to the lower end surface of the reagent plate (130). Waste liquid grooves (1501) corresponding to the reagent grooves (1301) one by one are provided on the upper end surface of the installation plate (150).

4. The nucleic acid extraction kit for preventing liquid leakage according to claim 3, wherein: A plurality of horizontally arranged first horizontal grooves (1502) are evenly distributed on the upper end surface of the installation plate (150). A plurality of vertically arranged first vertical grooves (1503) are evenly distributed on the upper end surface of the installation plate (150). The first horizontal grooves (1502) and the first vertical grooves (1503) intersect with each other to form a plurality of first grids (1504). At most one of the waste liquid grooves (1501) is arranged in each of the first grids (1504).

5. The nucleic acid extraction kit for preventing liquid leakage according to claim 4, characterized in that: First marking grids (1401) corresponding to the first grids (1504) one by one are provided on the upper end surface of the collection drawer (140). Numbers are sequentially engraved on each of the first marking grids (1401).

6. The nucleic acid extraction kit for preventing liquid leakage according to claim 5, characterized in that: A plurality of horizontally arranged second horizontal grooves (1303) are evenly distributed on the upper end surface of the reagent plate (130). A plurality of vertically arranged second vertical grooves (1304) are evenly distributed on the upper end surface of the reagent plate (130). The second horizontal grooves (1303) and the second vertical grooves (1304) intersect with each other to form a plurality of second grids (1305). At most one of the reagent grooves (1301) is arranged in each of the second grids (1305). Second marking grids (1306) corresponding to the second grids (1305) one by one are provided at the edge of the upper end surface of the reagent plate (130). Numbers are sequentially engraved on each of the second marking grids (1306).

7. The nucleic acid extraction kit for preventing liquid leakage according to claim 2, wherein; A first magnetic attraction plate (1103) is provided on the side wall of the collection cavity (1101) far from the installation hole (1102). A second magnetic attraction plate (1402) matched with the first magnetic attraction plate (1103) is provided on the side wall of the collection drawer (140).