Antibody incubation box
The antibody incubation box addresses container damage and mixing inefficiencies with a gear-driven, motor-oscillating mechanism and sponge structure, ensuring safe storage and uniform mixing for enhanced experimental efficiency.
Patent Information
- Application Number
- CN202421326645.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-12
- Publication Date
- 2025-07-15
- Estimated Expiration
- 2034-06-12
AI Technical Summary
The existing antibody incubation box is prone to damage the test tube when used, and cannot effectively mix antibodies, and is inconvenient to operate.
An antibody incubation box including a disk and a box is designed, and a mixing system driven by a sector gear and a motor is combined with a test tube sponge to protect the test tube to achieve safe access and uniform mixing of the test tube.
Improves experimental efficiency and accuracy, protects the test tube from damage, ensures that the antibodies are fully mixed, and enhances operating flexibility.
Smart Images
Figure CN223107826U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of antibody incubation boxes, in particular to an antibody incubation box. Background Art
[0002] Protein immunoblotting is an important and common basic experimental technique in biomedical research. Antibody incubation boxes are essential consumables in this process. Most current antibody incubation boxes are covered transparent plastic boxes with fixed internal partitions. In experiments, antibody diluents or washing solutions and protein membranes are placed in the partitions, and then the antibody incubation box is placed on a horizontal or seesaw-type shaker for light-shielded incubation or washing for several hours to overnight. In order to achieve the purpose of fully incubating or washing antibodies in the experiment, a large shaking amplitude of the shaker is often required, or the incubation time is increased.
[0003] When this antibody incubation box is in use, the following defects still exist: during the antibody incubation process, it is easy to damage the test tubes containing antibodies, thereby affecting the next experiment of the antibodies. During the antibody incubation process, mixing and agitation cannot be carried out according to requirements, so that the reactants cannot be fully mixed, affecting efficiency and uniformity, and it is inconvenient to take and place the test tubes for antibody incubation during antibody incubation. Content of the Utility Model
[0004] The purpose of the utility model is to solve the defects existing in the prior art, and to propose an antibody incubation box.
[0005] In order to achieve the above purpose, the utility model adopts the following technical scheme: an antibody incubation box, including a first disc and a box body. A sector gear one is rotatably connected to the box body. One end of the sector gear one is fixedly connected to a handle. A connecting rod one is fixedly connected to the sector gear one. One end of the connecting rod one is rotatably connected to a first box cover. The first box cover fits on the box body. A connecting rod two is rotatably connected to the first box cover. One end of the connecting rod two is rotatably connected to the box body. A connecting rod five is fixedly connected to the sector gear one. A connecting rod six is rotatably connected to the connecting rod five. One end of the connecting rod six is rotatably connected to a placement box. The placement box is slidably connected to the box body. A test tube sponge is provided in the placement box. The test tube sponge is provided with holes. A sector gear two is meshed with the sector gear one. The sector gear two is rotatably connected to the box body. A connecting rod three is fixedly connected to the sector gear two. One end of the connecting rod three is rotatably connected to a second box cover. The second box cover fits on the box body. A connecting rod four is rotatably connected to the second box cover. One end of the connecting rod four is rotatably connected to the box body. A connecting rod eight is fixedly connected to the sector gear two. A connecting rod seven is rotatably connected to the connecting rod eight. One end of the connecting rod seven is rotatably connected to the placement box. The box body fits on the first disc.
[0006] As a further description of the above technical solution: A first cylinder is fixedly connected to the bottom of the first disc. A fixed frame is rotatably connected to the first cylinder. A second cylinder is rotatably connected to the fixed frame. One end of the second cylinder is fixedly connected to a fixing plate. One end of the fixing plate is fixedly connected to a second disc. A motor is fixedly connected to the second disc. An output end of the motor is fixedly connected to a connecting member. The connecting member is rotatably connected to the first cylinder.
[0007] As a further description of the above technical solution: A fixed box is fixedly connected to the first disc. A spring is fixedly connected inside the fixed box. One end of the spring is fixedly connected to a sliding rod. A fixed block is fixedly connected to the sliding rod. The sliding rod slides inside the fixed box. One end of the sliding rod is slidably connected to the box body.
[0008] As a further description of the above technical solution: The placement box is arranged inside the box body. The test tube sponge is arranged inside the placement box.
[0009] As a further description of the above technical solution: The first sector gear and the second sector gear are symmetrically arranged. The first connecting rod and the third connecting rod are symmetrically arranged. The second connecting rod and the fourth connecting rod are symmetrically arranged. The eighth connecting rod and the fifth connecting rod are symmetrically arranged. The seventh connecting rod and the sixth connecting rod are symmetrically arranged.
[0010] As a further description of the above technical solution: One end of the first sector gear penetrates through the box body. One end of the second sector gear penetrates through the box body.
[0011] As a further description of the above technical solution: There are two groups of fixed boxes, two groups of springs, two groups of fixed blocks, and two groups of sliding rods.
[0012] The utility model has the following beneficial effects:
[0013] In the utility model, when using the antibody incubation box, through the sliding of the box body, the first box cover and the second box cover, and the test tube sponge inside the placement box, the incubation box is not only convenient for quickly storing and retrieving test tubes, but also can effectively prevent the test tubes from rolling or breaking during storage, greatly improving the efficiency of experimental operations. At the same time, it also provides a safe incubation environment for the antibodies in the test tubes. Moreover, the elasticity and buffering effect of the test tube sponge can protect the test tubes from collision and damage, reducing the risk of experimental failure.
[0014] In the present utility model, when using the antibody incubation box, the motor drives the disc and the box body to shake regularly, so that the antibody in the test tube can be evenly mixed. This mixing method not only improves the accuracy and efficiency of the experiment, but also ensures the full mixing of the reactants, thereby improving the efficiency and uniformity of the reaction. By pulling the fixing block, it is convenient for the experimenter to remove the box body and take out the test tube when shaking is not required, greatly enhancing the flexibility of the operation. BRIEF DESCRIPTION OF THE DRAWINGS
[0015] Figure 1 Structural schematic diagram of an antibody incubation box proposed by the present utility model Figure 1 ;
[0016] Figure 2 Structural schematic diagram of an antibody incubation box proposed by the present utility model Figure 2 ;
[0017] Figure 3 Cross-sectional view of an antibody incubation box proposed by the present utility model;
[0018] Figure 4 is Figure 1 Enlarged view of part A in
[0019] Legend description:
[0020] 1. Disc 1; 2. Box body; 3. Sector gear 1; 4. Handle; 5. Connecting rod 1; 6. Box cover 1; 7. Connecting rod 2; 8. Sector gear 2; 9. Connecting rod 3; 10. Box cover 2; 11. Connecting rod 4; 12. Connecting rod 5; 13. Connecting rod 6; 14. Placing box; 15. Connecting rod 7; 16. Connecting rod 8; 17. Cylinder 1; 18. Fixed frame; 19. Fixed plate; 20. Disc 2; 21. Motor; 22. Connector; 23. Cylinder 2; 24. Fixed box; 25. Spring; 26. Fixed block; 27. Slide bar; 28. Hole; 29. Test tube sponge. DETAILED DESCRIPTION OF THE EMBODIMENTS
[0021] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present utility model.
[0022] Refer to Figures 1 - 4, an embodiment provided by the present utility model: an antibody incubation box, comprising a first disc 1 and a box body 2. A first sector gear 3 is rotatably connected to the box body 2. One end of the first sector gear 3 is fixedly connected to a handle 4. A first connecting rod 5 is fixedly connected to the first sector gear 3. One end of the first connecting rod 5 is rotatably connected to a first box cover 6. The first box cover 6 is attached to the box body 2. A second connecting rod 7 is rotatably connected to the first box cover 6. One end of the second connecting rod 7 is rotatably connected to the box body 2. A fifth connecting rod 12 is fixedly connected to the first sector gear 3. A sixth connecting rod 13 is rotatably connected to the fifth connecting rod 12. One end of the sixth connecting rod 13 is rotatably connected to a placement box 14. The placement box 14 is slidably connected to the box body 2. A test tube sponge 29 is provided in the placement box 14. A hole 28 is provided in the test tube sponge 29. A second sector gear 8 is meshed with the first sector gear 3. The second sector gear 8 is rotatably connected to the box body 2. A third connecting rod 9 is fixedly connected to the second sector gear 8. One end of the third connecting rod 9 is rotatably connected to a second box cover 10. The second box cover 10 is attached to the box body 2. A fourth connecting rod 11 is rotatably connected to the second box cover 10. One end of the fourth connecting rod 11 is rotatably connected to the box body 2. An eighth connecting rod 16 is fixedly connected to the second sector gear 8. A seventh connecting rod 15 is rotatably connected to the eighth connecting rod 16. One end of the seventh connecting rod 15 is rotatably connected to the placement box 14. The box body 2 is attached to the first disc 1. When using the antibody incubation box, through the sliding of the box body 2, the first box cover 6 and the second box cover 10, and the test tube sponge 29 in the placement box 14, the incubation box is not only convenient for quickly accessing and storing test tubes, but also can effectively prevent the test tubes from rolling or breaking during storage, greatly improving the efficiency of experimental operations. At the same time, it also provides a safe incubation environment for the antibodies in the test tubes. Moreover, the elasticity and buffering effect of the test tube sponge 29 can protect the test tubes from collision and damage, reducing the risk of experimental failure.
[0023] A first cylinder 17 is fixedly connected to the bottom of a first disc 1. A fixed frame 18 is rotatably connected to the first cylinder 17. A second cylinder 23 is rotatably connected to the fixed frame 18. A fixing plate 19 is fixedly connected to one end of the second cylinder 23. A second disc 20 is fixedly connected to one end of the fixing plate 19. A motor 21 is fixedly connected to the second disc 20. A connecting member 22 is fixedly connected to the output end of the motor 21. The connecting member 22 is rotatably connected to the first cylinder 17. A fixed box 24 is fixedly connected to the first disc 1. A spring 25 is fixedly connected inside the fixed box 24. A sliding rod 27 is fixedly connected to one end of the spring 25. A fixed block 26 is fixedly connected to the sliding rod 27. The sliding rod 27 slides inside the fixed box 24. One end of the sliding rod 27 is slidably connected to the second body 2. A placement box 14 is arranged inside the second body 2. A test tube sponge 29 is arranged inside the placement box 14. A first sector gear 3 and a second sector gear 8 are symmetrically arranged. A first connecting rod 5 and a third connecting rod 9 are symmetrically arranged. A second connecting rod 7 and a fourth connecting rod 11 are symmetrically arranged. An eighth connecting rod 16 and a fifth connecting rod 12 are symmetrically arranged. A seventh connecting rod 15 and a sixth connecting rod 13 are symmetrically arranged. One end of the first sector gear 3 penetrates through the second body 2. One end of the second sector gear 8 penetrates through the second body 2. There are two groups of fixed boxes 24, two groups of springs 25, two groups of fixed blocks 26, and two groups of sliding rods 27. When using the antibody incubation box, the motor 21 drives the disc and the second body 2 to shake regularly, so that the antibody in the test tube can be evenly mixed. This mixing method not only improves the accuracy and efficiency of the experiment, but also ensures the full mixing of the reactants, thereby improving the efficiency and uniformity of the reaction. By pulling the fixed block 26, it is convenient for the experimenter to remove the second body 2 and take out the test tube when shaking is not required, greatly enhancing the flexibility of the operation.
[0024] Working principle: When using the antibody incubation box, the staff first turn the handle 4. The handle 4 drives the first sector gear 3 to rotate on the box body 2. The first sector gear 3 drives the first connecting rod 5 to move. The first connecting rod 5 drives the first box cover 6 to slide to one side on the box body 2 through the second connecting rod 7. At the same time, the first sector gear 3 drives the second sector gear 8 to rotate on the box body 2 through meshing connection. The second sector gear 8 drives the third connecting rod 9 to move. The third connecting rod 9 drives the second box cover 10 to slide to one side on the box body 2 through the fourth connecting rod 11, which is convenient for opening and closing the box body 2. At the same time, the first sector gear 3 and the second sector gear 8 drive the fifth connecting rod 12 and the eighth connecting rod 16 to move. The fifth connecting rod 12 and the eighth connecting rod 16 drive the sixth connecting rod 13 and the seventh connecting rod 15 to move. The movement of the sixth connecting rod 13 and the seventh connecting rod 15 drives the placement box 14 to slide upward in the box body 2, so that the first box cover 6 and the second box cover 10 slide in opposite directions on the box body 2 while the placement box 14 slides upward synchronously in the box body 2, which is suitable for storing test tubes containing antibodies during antibody incubation. After the antibody is loaded into the test tube, the test tube is sealed with a test tube stopper. And the placement box 14 is provided with a test tube sponge 29, and the test tube sponge 29 is provided with holes 28, which is suitable for preventing the test tube from rolling or breaking during storage, and has certain elasticity and buffering effect to protect the test tube from collision and damage. After the test tube containing the antibody is placed in the holes 28 on the test tube sponge 29, turn the handle 4 in the reverse direction to reset the first box cover 6 and the second box cover 10, and synchronously drive the placement box 14 to slide and reset in the box body 2. When the antibody incubation requires mixing or stirring, the staff turn on the motor 21. The motor 21 drives the connecting piece 22 to rotate. The connecting piece 22 drives the first cylinder 17 to rotate on the fixed frame 18. Through the rotation amplitude of the first cylinder 17, the fixed frame 18 rotates on the second cylinder 23, so as to drive the box body 2 on the first disc 1 to shake through the first cylinder 17, so that the antibody in the test tube on the test tube sponge 29 is evenly mixed, ensuring sufficient mixing of the reactants while improving the reaction efficiency and uniformity. And a fixed box 24 is provided on the first disc 1. When the antibody in the test tube does not need to be shaken, the staff pull two groups of fixed blocks 26. The fixed blocks 26 drive the slide rod 27 to compress the spring 25. When one end of the slide rod 27 slides out of the groove on the box body 2, the box body 2 can be removed, which is convenient for locking and opening the box body 2.
[0025] Finally, it should be noted that the above are only the preferred embodiments of the present invention and are not used to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, for those skilled in the art, they can still modify the technical solutions described in the foregoing embodiments, or perform equivalent replacements for some of the technical features. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.
Claims
1. An antibody incubation box, comprising a first disc (1) and a box body (2), characterized in that: A sector gear one (3) is rotatably connected to the box body (2). One end of the sector gear one (3) is fixedly connected to a handle (4). A connecting rod one (5) is fixedly connected to the sector gear one (3). One end of the connecting rod one (5) is rotatably connected to a box cover one (6). The box cover one (6) is attached to the box body (2). A connecting rod two (7) is rotatably connected to the box cover one (6). One end of the connecting rod two (7) is rotatably connected to the box body (2). A connecting rod five (12) is fixedly connected to the sector gear one (3). A connecting rod six (13) is rotatably connected to the connecting rod five (12). One end of the connecting rod six (13) is rotatably connected to a placement box (14). The placement box (14) is slidably connected to the box body (2). A test tube sponge (29) is provided in the placement box (14). A hole (28) is provided in the test tube sponge (29). The sector gear one (3) is meshed with a sector gear two (8). The sector gear two (8) is rotatably connected to the box body (2). A connecting rod three (9) is fixedly connected to the sector gear two (8). One end of the connecting rod three (9) is rotatably connected to a box cover two (10). The box cover two (10) is attached to the box body (2). A connecting rod four (11) is rotatably connected to the box cover two (10). One end of the connecting rod four (11) is rotatably connected to the box body (2). A connecting rod eight (16) is fixedly connected to the sector gear two (8). A connecting rod seven (15) is rotatably connected to the connecting rod eight (16). One end of the connecting rod seven (15) is rotatably connected to the placement box (14). The box body (2) is attached to the disc one (1).
2. The antibody incubation box according to claim 1, wherein: A cylinder one (17) is fixedly connected to the bottom of the disc one (1). A fixed frame (18) is rotatably connected to the cylinder one (17). A cylinder two (23) is rotatably connected to the fixed frame (18). One end of the cylinder two (23) is fixedly connected to a fixing plate (19). One end of the fixing plate (19) is fixedly connected to a disc two (20). A motor (21) is fixedly connected to the disc two (20). An output end of the motor (21) is fixedly connected to a connecting part (22). The connecting part (22) is rotatably connected to the cylinder one (17).
3. The antibody incubation box according to claim 2, characterized in that: A fixed box (24) is fixedly connected to the disc one (1). A spring (25) is fixedly connected inside the fixed box (24). One end of the spring (25) is fixedly connected to a sliding rod (27). A fixed block (26) is fixedly connected to the sliding rod (27). The sliding rod (27) slides inside the fixed box (24). One end of the sliding rod (27) is slidably connected to the box body (2).
4. The antibody incubation box according to claim 3, wherein: The placement box (14) is arranged inside the box body (2). The test tube sponge (29) is arranged inside the placement box (14).
5. An antibody incubation cassette according to claim 4, wherein: The sector gear one (3) and the sector gear two (8) are symmetrically arranged, the connecting rod one (5) and the connecting rod three (9) are symmetrically arranged, the connecting rod two (7) and the connecting rod four (11) are symmetrically arranged, the connecting rod eight (16) and the connecting rod five (12) are symmetrically arranged, and the connecting rod seven (15) and the connecting rod six (13) are symmetrically arranged.
6. The antibody incubation box according to claim 5, characterized in that: One end of the sector gear one (3) penetrates through the box body (2), and one end of the sector gear two (8) penetrates through the box body (2).
7. An antibody incubation box according to claim 6, characterized in that: There are two groups of fixed boxes (24), two groups of springs (25), two groups of fixed blocks (26), and two groups of sliding rods (27).