Sample bin and imaging equipment
The dual-glass structure with a sealing mechanism for buffer solution in the sample holder addresses the issues of slide movement and buffer leakage/oxidation, ensuring stable and contamination-free sample observation.
Patent Information
- Application Number
- CN202422055456.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-08-23
- Publication Date
- 2025-07-15
- Estimated Expiration
- 2034-08-23
AI Technical Summary
The slides are easily moved when observing the sample and the buffer is exposed to the outside world, resulting in buffer leakage and oxidation reactions, affecting the observation results and potentially contaminating the microscope components.
A sample compartment is designed, including a first cover and a second cover, fixing the slide through a projection and a seal, and the liquid reservoir is stored in the buffer, and the liquid reservoir is closed by a sealing plug to prevent the buffer from flowing out and oxidation.
The stable fixation of the slide is achieved, avoiding buffer leakage and oxidation, reducing fixation time, protecting the sample from contamination, and improving imaging quality and the accuracy of experimental results.
Smart Images
Figure CN223108153U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of sample chambers, and particularly to a sample chamber and an imaging device. Background Art
[0002] When observing a sample, a buffer solution is often added to the sample. However, since the glass slide is prone to move during observation and the buffer solution is exposed to the outside, there is a situation where the buffer solution spills, corrodes the microscope components, and undergoes an oxidation reaction, affecting the observation results.
[0003] In the related art, the glass slide is fixed with glue, and a cover glass is further covered on the glass slide. The glass slide and the cover glass are fixed with glue to avoid situations such as buffer solution spillage and oxidation reaction when observing the sample. However, the time required for fixing with glue is long, and the glue may contaminate the sample. Summary of the Utility Model
[0004] The utility model aims to at least solve one of the technical problems existing in the prior art. For this purpose, the utility model provides a sample chamber, which can reduce the fixing time and protect the sample from contamination while fixing the glass slide and preventing the buffer solution from spilling and oxidizing.
[0005] The utility model also provides an imaging device having the above sample chamber.
[0006] The sample chamber according to the first aspect embodiment of the utility model includes:
[0007] A main body member, including a first cover and a second cover. The first cover is connected to the second cover, and a first support surface is provided on the side facing the second cover. The second cover has a hollow structure, and a protrusion is provided on the side facing the first cover. The protrusion covers the first support surface and jointly defines a receiving cavity with the first support surface.
[0008] A storage component, including a liquid storage member and a sealing plug. The liquid storage member passes through the hollow structure. The liquid storage member has a first end and a second end. A liquid storage channel is defined inside the liquid storage member, which penetrates through the first end and the second end. The first end is disposed in the receiving cavity and communicates with the receiving cavity, and the second end is connected to the sealing plug; and
[0009] A sealing member, disposed in the receiving cavity. The sealing member is located between the protrusion and the liquid storage member and is circumferentially disposed on the outer wall surface of the first end.
[0010] The sample chamber according to the embodiments of the present utility model has at least the following beneficial effects: The glass slide is accommodated in the accommodation cavity by the first support surface and the protrusion, and the glass slide is pressed by the seal to prevent the glass slide from moving. The liquid storage member contains a buffer solution, and the buffer solution contacts the glass slide through the first end to enable normal observation of the glass slide. The seal is connected between the protrusion and the liquid storage member to seal the accommodation cavity and prevent the buffer solution from flowing out of the accommodation cavity. The seal plug is used to seal the liquid storage member and isolate the buffer solution from the outside, thereby achieving the reduction of the fixation time of the glass slide and protecting the sample from contamination without the glass slide moving and the buffer solution leaking or oxidizing.
[0011] According to some embodiments of the present utility model, it further includes a fastener. The first cover body and the second cover body are provided with through holes, and the fastener passes through the through holes to connect and fix the first cover body and the second cover body.
[0012] According to some embodiments of the present utility model, the protrusion includes a fixing portion and a abutting portion. The abutting portion extends toward the first support surface relative to the fixing portion and forms an accommodation groove with the fixing portion. The seal is press-fitted in the accommodation groove.
[0013] According to some embodiments of the present utility model, the first cover body further includes a first abutting surface, which is recessed from the side of the first cover body facing the second cover body. The first abutting surface is connected to the first support surface, and the fixing portion is connected to the first abutting surface.
[0014] According to some embodiments of the present utility model, the seal plug includes a limiting portion and a connecting portion. The limiting portion is connected to the connecting portion. The connecting portion extends from the seal plug toward the liquid storage member. The connecting portion is accommodated in the liquid storage channel, and the limiting portion is provided at the second end.
[0015] According to some embodiments of the present utility model, the seal plug is made of a visible material.
[0016] According to some embodiments of the present utility model, it further includes a base. The base has an opposite upper side and a lower side. The upper side is recessed toward the lower side to form a support seat. The support seat includes a second support surface and a second abutting surface, and the second support surface is connected to the second abutting surface.
[0017] According to some embodiments of the present utility model, the first cover body is provided on the support seat. The second support surface is connected to the bottom of the first cover body, and the second abutting surface is connected to the side wall of the first cover body. The support seat is used to position the first cover body.
[0018] According to some embodiments of the present utility model, accommodation holes are provided at the bottom of the first cover body and the second support surface, a magnetic member is accommodated in the accommodation holes, and the second support surface is detachably connected to the second support surface through the magnetic member.
[0019] An imaging device according to an embodiment of the second aspect of the present utility model includes:
[0020] A microscope including a stage;
[0021] The sample chamber according to any one of the above embodiments, connected to the stage;
[0022] A glass slide accommodated in the accommodation chamber.
[0023] The imaging device according to an embodiment of the present utility model has at least the following beneficial effects: The glass slide can be stably fixed through the sample chamber, avoiding the situation that the observation result of the sample is affected due to the movement of the glass slide. At the same time, it can also prevent the buffer solution from leaking and corroding the microscope components and the oxidation reaction of the buffer solution, thereby improving the imaging quality and the accuracy of the experimental results.
[0024] Additional aspects and advantages of the present utility model will be given in part in the following description, become apparent in part from the following description, or be understood through the practice of the present utility model. Description of the Drawings
[0025] The following further describes the present utility model in conjunction with the drawings and embodiments, where:
[0026] Figure 1 is a schematic diagram of the sample chamber in an embodiment of the present utility model;
[0027] Figure 2 is an exploded schematic diagram of the sample chamber in an embodiment of the present utility model;
[0028] Figure 3 is a schematic diagram of the main body member in an embodiment of the present utility model;
[0029] Figure 4 is in an embodiment of the present utility model Figure 3 A-A cross-sectional schematic diagram;
[0030] Figure 5 is an exploded schematic diagram of the main body member in an embodiment of the present utility model;
[0031] Figure 6 is a schematic diagram of the sample chamber in an embodiment of the present utility model;
[0032] Figure 7 is in an embodiment of the present utility model Figure 6 B-B cross-sectional schematic diagram;
[0033] Figure 8 In the embodiment of the present utility model Figure 7 is an enlarged schematic view of part C;
[0034] Figure 9 is a schematic view of the storage component in the embodiment of the present utility model;
[0035] Figure 10 is a schematic view of the first cover in the embodiment of the present utility model;
[0036] Figure 11 is a schematic view of the base in the embodiment of the present utility model.
[0037] Reference numerals:
[0038] Main body 100; First cover 110; First support surface 111; Through hole 112; First abutting surface 113; Concave structure 114; Observation window 115; Second cover 120; Hollow structure 121; Protrusion 122; Fixing part 1221; Abutting part 1222; Receiving groove 1223; Opening 123; Receiving cavity 124;
[0039] Storage component 200; Liquid storage member 210; Liquid storage channel 211; First end 2111; Second end 2112; Sealing plug 220; Limiting part 221; Connecting part 222;
[0040] Sealing member 300;
[0041] Base 400; Support seat 410; Second support surface 411; Receiving hole 412; Second abutting surface 413;
[0042] Fastener 500; Glass slide 600. Detailed implementation manners
[0043] The embodiments of the present utility model will be described in detail below. The examples of the embodiments are shown in the drawings, wherein the same or similar reference numerals indicate the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the drawings are exemplary and are only used to explain the present utility model and should not be construed as a limitation to the present utility model.
[0044] In the description of the present utility model, it should be understood that the orientation or positional relationship indicated by terms such as up, down, front, back, left, right, etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present utility model and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as a limitation to the present utility model.
[0045] In the description of the present utility model, the meaning of "several" is more than one, the meaning of "multiple" is more than two, and understandings such as "greater than", "less than", "exceeding", etc. do not include the present number, and understandings such as "above", "below", "within", etc. include the present number. If there is a description of "first" and "second", it is only for the purpose of distinguishing technical features, and cannot be understood as indicating or implying relative importance or implicitly indicating the quantity of the indicated technical features or implicitly indicating the sequence relationship of the indicated technical features.
[0046] In the description of the present utility model, unless otherwise clearly defined, words such as "arrangement", "installation", "connection", etc. should be understood in a broad sense, and those skilled in the art can reasonably determine the specific meanings of the above words in the present utility model in combination with the specific content of the technical solution.
[0047] In the description of the present utility model, the description with reference to terms such as "one embodiment", "some embodiments", "schematic embodiments", "examples", "specific examples", or "some examples", etc. means that the specific features, structures, materials, or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the present utility model. In this specification, the schematic expressions of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials, or characteristics described can be combined in a suitable manner in any one or more embodiments or examples.
[0048] Next, with reference to the accompanying drawings of the specification, the sample chamber of the first aspect embodiment of the present utility model will be described.
[0049] The embodiment of the present utility model provides a sample chamber for observing a sample slide. Refer to Figures 1 to 4 As shown, the sample chamber includes a main body member 100, a storage assembly 200, and a sealing member 300. Among them, the main body member 100 includes a first cover body 110 and a second cover body 120. The first cover body 110 is connected to the second cover body 120. A first support surface 111 is provided on the side of the first cover body 110 facing the second cover body 120, and the first support surface 111 is used for placing the slide 600. The second cover body 120 has a hollow structure 121. A convex portion 122 is provided on the side of the second cover body 120 facing the first cover body 110, and the convex portion 122 covers the first support surface 111. The convex portion 122 and the first support surface 111 jointly define a receiving cavity 124. When it is necessary to observe the slide 600 loaded with a sample, the slide 600 is placed on the first support surface 111, and the slide 600 is received in the receiving cavity 124. The first support surface 111 and the receiving cavity 124 limit the slide 600 within a certain space range, reducing the movement of the slide 600.
[0050] The storage component 200 includes a liquid storage member 210 and a sealing plug 220. The liquid storage member 210 is disposed through the hollow structure 121. Since the second cover 120 has the hollow structure 121, the liquid storage member 210 is inserted into the hollow structure 121 to form a connection with the second cover 120. The liquid storage member 210 defines a liquid storage channel 211 for accommodating the buffer solution. The liquid storage member 210 has a first end 2111 and a second end 2112, and the liquid storage channel 211 penetrates through the first end 2111 and the second end 2112 of the liquid storage member 210. Among them, when the liquid storage member 210 is disposed through the hollow structure 121 of the second cover 120, the first end 2111 of the liquid storage member 210 is located in the accommodation cavity 124 and the liquid storage channel 211 communicates with the accommodation cavity 124. The buffer solution enters the accommodation cavity 124 through the liquid storage channel 211 to contact the sample on the glass slide 600. The sealing plug 220 is connected to the second end 2112 of the liquid storage member 210. The sealing plug 220 is used to seal the second end 2112 of the liquid storage member 210 to prevent external air from entering the liquid storage channel 211 and the accommodation cavity 124 through the second end 2112, avoiding the oxidation reaction of the buffer solution in the liquid storage channel 211 and the entry of impurities in the air into the accommodation cavity 124 to contact the sample, resulting in sample contamination.
[0051] The seal 300 is disposed in the accommodation cavity 124. The seal 300 is located between the protrusion 122 and the liquid storage member 210, and the seal 300 surrounds the outer wall surface of the first end 2111. The seal 300 is used to abut against the glass slide 600 disposed in the accommodation cavity 124 and prevent the buffer solution from leaking. The seal 300 is made of an elastic material. In this embodiment, the seal 300 is specifically a rubber material. In other embodiments, the seal 300 can also be a silicone material, or a polyurethane sealing ring, or a plastic material, etc. Specifically, when the glass slide 600 is located in the accommodation cavity 124, the seal 300 will contact the glass slide 600 and apply a certain pressure to the glass slide 600, so that the glass slide 600 cannot move in the accommodation cavity 124 under the pressing of the seal 300, facilitating the experimental observation of the glass slide 600. Moreover, the seal 300 is located between the protrusion 122 and the liquid storage member 210, and the seal 300 is connected to the protrusion 122 and the liquid storage member 210. Among them, the connection between the seal 300 and the protrusion 122 can prevent the buffer solution located in the accommodation cavity 124 from flowing out of the accommodation cavity 124 through the gap between the protrusion 122 and the first support surface 111, and the connection between the seal 300 and the outer wall surface of the liquid storage member 210 can also prevent the buffer solution from flowing out of the accommodation cavity 124 along the gap between the seal 300 and the outer wall surface of the liquid storage member 210.
[0052] The seal 300 can be disposed in the receiving cavity 124 in a variety of ways. For example, in some embodiments, the seal 300 can be connected to the protrusion 122. After the liquid storage member 210 is inserted through the hollow structure 121, the seal 300 is located between the liquid storage member 210 and the protrusion 122, and the seal 300 is in contact with the outer wall surface of the liquid storage member 210. Alternatively, in some embodiments, the seal 300 can be connected to the liquid storage member 210. Specifically, the seal 300 is connected to the outer wall surface of the first end 2111 of the liquid storage member 210. Before the second cover 120 is connected to the first cover 110, the liquid storage member 210 connected with the seal 300 is first inserted through the hollow structure 121, so that the seal 300 can be received in the receiving cavity 124 to press against the glass slide 600. Or, in some other embodiments, in a state where the liquid storage member 210 is inserted through the hollow structure 121, a receiving groove 1223 is defined between the liquid storage member 210 and the protrusion 122, and the seal 300 is press-fitted into the receiving groove 1223, and the liquid storage member 210 and the protrusion 122 jointly clamp the seal 300.
[0053] Specifically, when it is necessary to observe the sample, the glass slide 600 loaded with the sample needs to be placed on the first support surface 111, and the glass slide 600 is received in the receiving cavity 124 through the cooperation of the first cover 110 and the second cover 120, and the seal 300 applies pressure to the glass slide 600 to restrict the movement of the glass slide 600. After the liquid storage member 210 is inserted through the hollow structure 121 of the second cover 120, a buffer solution is injected into the receiving cavity 124, so that the buffer solution and the sample are combined and the sample can be normally observed. The seal 300 is disposed between the protrusion 122 and the liquid storage member 210 to seal the receiving cavity 124 and prevent the buffer solution from flowing out of the receiving cavity 124. The sealing plug 220 is used to seal the liquid storage member 210 to isolate the buffer solution from the outside. Thus, the glass slide 600 will neither move in the receiving cavity 124 nor will the buffer solution leak or oxidize. At the same time, since the connection between the main body member 100, the storage assembly 200 and the seal 300 is simple and convenient for assembly, it is possible to reduce the fixing time of the glass slide 600 and protect the sample from being contaminated without the glass slide 600 moving and the buffer solution leaking or oxidizing.
[0054] In some embodiments, refer to Figure 1 and Figure 2As shown, the sample chamber further includes a base 400 having opposite upper and lower sides. Among them, a support seat 410 is formed by the upper side of the base 400 being recessed towards the lower side of the base 400. The support seat 410 includes a second support surface 411 and a second abutting surface 413, and the second support surface 411 is connected to the second abutting surface 413. Specifically, the support seat 410 is formed by the upper side of the base 400 being recessed towards the lower side of the base 400. Among them, the support seat 410 is a structure with a depth, the support seat 410 has a bottom surface and a side wall, the bottom surface of the support seat 410 is the second support surface 411, and the inner side wall of the support seat 410 is the second abutting surface 413. The second abutting surface 413 is connected to the second support surface 411, and the second abutting surface 413 and the second support surface 411 are used to connect the first cover 110. After the main body 100 finishes fixing the glass slide 600, the first cover 110 is then connected to the support seat 410. The first cover 110 is placed on the base 400, and the first cover 110 is fixed by the support seat 410 of the base 400, so that the glass slide 600 can be observed normally.
[0055] In some embodiments, referring to Figure 11 As shown, the first cover 110 is disposed on the support seat 410. The second support surface 411 is connected to the bottom of the first cover 110, and the second abutting surface 413 is connected to the side wall of the first cover 110. The support seat 410 is used to position the first cover 110. Specifically, when the first cover 110 is connected to the base 400, the first cover 110 is located in the support seat 410. At this time, the second support surface 411 is used to support the bottom of the first cover 110, the second abutting surface 413 and the outer side wall of the first cover 110 are in mutual abutment, and the second abutting surface 413 is used to limit the movement of the first cover 110 relative to the base 400. The second support surface 411 and the second abutting surface 413 define the connection position of the first cover 110 and the base 400, and jointly position the first cover 110.
[0056] Further, in some embodiments, referring to Figure 5 and Figure 11As shown, accommodation holes 412 are provided at the bottom of the first cover body 110 and the second support surface 411, and magnetic components are accommodated in the accommodation holes 412. The second support surface 411 is detachably connected to the second support surface 411 through the magnetic components. The second support surface 411 hinders the first cover body 110 from rotating relative to the base 400 through the magnetic components in the accommodation holes 412, so as to facilitate the observation of the sample. Specifically, the bottom of the first cover body 110 and the second support surface 411 are magnetically connected to the base 400 by arranging magnetic components in the accommodation holes 412. Using the magnetic connection method can ensure that the first cover body 110 is stably fixed on the base 400, and the main body 100 is not likely to move relative to the base 400 without external force. At the same time, the magnetic connection method facilitates the disassembly of the first cover body 110 and the base 400.
[0057] In some embodiments, referring to Figure 1 、 Figure 2 and Figure 7 As shown, the sample chamber further includes a fastener 500. Through holes 112 are provided on the first cover body 110 and the second cover body 120. The fastener 500 passes through the through holes 112 to connect and fix the first cover body 110 and the second cover body 120. Specifically, in this embodiment, the fastener 500 is a screw. Through holes 112 are formed on the first cover body 110 and the second cover body 120, and internal threads are provided on the inner walls of the through holes 112. The fastener 500 is threadedly connected to the through holes 112 to connect and fix the first cover body 110 and the second cover body 120 into one body. Further, in some embodiments, an opening 123 is further provided on the side wall of the second cover body 120. The opening 123 communicates with the through hole 112, and the opening 123 extends toward the position where the through hole 112 is provided, so as to communicate with the through hole 112. Providing the opening 123 and connecting the opening 123 and the through hole 112 can facilitate observing the position of the fastener 500 when the fastener 500 passes through the through hole 112, and judging the locking degree of the first cover body 110 and the second cover body 120 according to the position of the fastener 500.
[0058] In some embodiments (not shown in the figure), the fastener 500 can also be other components, such as a magnetic component. Through holes 112 are provided on the side of the first cover body 110 facing the second cover body 120 and the side of the second cover body 120 facing the first cover body 110, and the magnetic component is accommodated in the through holes 112, so that the first cover body 110 and the second cover body 120 are connected by magnetic attraction. In this embodiment, it is not necessary to provide an opening 123 to observe the connection of the first cover body 110 and the second cover body 120.
[0059] In other embodiments (not shown in the figures), through holes 112 may be provided only on one of the first cover 110 or the second cover 120, and a snap structure may be provided on the other component without the through holes 112, such that the first cover 110 and the second cover 120 can be detachably connected by snap connection. In another embodiment (not shown in the figures), the first cover 110 and the second cover 120 may not be detachably connected. For example, the first cover 110 and the second cover 120 are integrally connected, and a placement opening is provided on the side wall of the first cover 110 or the second cover 120. The placement opening communicates with the accommodation cavity 124, and the glass slide 600 can be inserted or removed through the placement opening.
[0060] In some embodiments, referring to Figure 4 , Figure 5 and Figure 8 as shown, the protrusion 122 includes a fixing portion 1221 and a resisting portion 1222. The resisting portion 1222 is connected to the bottom surface of the fixing portion 1221 and extends from the bottom surface of the fixing portion 1221 toward the first support surface 111. The liquid storage member 210, the resisting portion 1222 and the bottom surface of the fixing portion 1221 together form a receiving groove 1223, and the sealing member 300 is press-fitted into the receiving groove 1223. Specifically, the resisting portion 1222 extends from the bottom of the fixing portion 1221 toward the first support surface 111. The fixing portion 1221 covers the first support surface 111, and the resisting portion 1222 is located between the first support surface 111 and the fixing portion 1221. The resisting portion 1222, the bottom of the fixing portion 1221 and the first support surface 111 together form an accommodation cavity 124 for receiving the glass slide 600. The resisting portion 1222 and the bottom of the fixing portion 1221 together form the receiving groove 1223, and the receiving groove 1223 is used to connect and fix the sealing member 300. The sealing member 300 is press-fitted into the receiving groove 1223. Referring to Figure 6 and Figure 7 as shown, when the liquid storage member 210 is inserted through the hollow structure 121 of the second cover 120, the liquid storage member 210 will contact the sealing member 300, and the sealing member 300 is provided around the outer wall surface of the liquid storage member 210. The second cover 120 can be positioned in the first cover 110 through the fixing portion 1221 and will not move relative to the first cover 110, strengthening the connection and fixing relationship between the first cover 110 and the second cover 120.
[0061] In other embodiments (not shown in the figures), the protrusion 122 may not include the fixing portion 1221. For example, the protrusion 122 is the resisting portion 1222, and the resisting portion 1222 extends from the side of the second cover 120 facing the first cover 110. The resisting portion 1222 is connected to the sealing member 300, and the glass slide 600 is fixed by the sealing member 300, thereby also achieving the fixation of the glass slide 600.
[0062] In some embodiments, see Figure 4 and Figure 8 As shown, the first cover body 110 further includes a first abutting surface 113 , which is formed by a depression on one side of the first cover body 110 toward the second cover body 120 , is connected to the first supporting surface 111 , and the fixing portion 1221 is connected to the first abutting surface 113 .
[0063] Specifically, see Figure 8 and Figure 10 As shown, the first cover 110 is provided with a recessed structure 114, one end of the second cover 120 is provided in the recessed structure 114, the inner peripheral wall of the recessed structure 114 defines a first abutting surface 113, the recessed structure 114 has a bottom surface on the side facing the second cover 120, and an observation window 115 is provided on the bottom surface, and the observation window 115 passes through the bottom surface of the recessed structure 114 and the surface of the first cover 110 on the side facing away from the second cover 120. The bottom surface of the recessed structure 114 defines a first supporting surface 111, and the first supporting surface 111 surrounds the outer peripheral side of the observation window 115. The first abutting surface 113 is connected to the first supporting surface 111. When the second cover 120 is connected to the first cover 110, the protrusion 122 of the second cover 120 will be connected to the recessed structure 114 of the first cover 110. At this time, the fixing portion 1221 contacts the first abutting surface 113 , thereby positioning the second cover 120 and preventing the second cover 120 from moving circumferentially relative to the first cover 110 after being connected to the first cover 110 .
[0064] In some embodiments, see Figure 2 and Figure 9 As shown, the sealing plug 220 includes a limiting portion 221 and a connecting portion 222, the limiting portion 221 is connected to the connecting portion 222, the connecting portion 222 is formed by the sealing plug 220 extending toward the liquid storage member 210, the connecting portion 222 is accommodated in the liquid storage channel 211, and the limiting portion 221 is connected to the second end 2112. Specifically, the sealing plug 220 is used to seal the second end 2112 of the liquid storage member 210, so that external gas and impurities cannot enter the liquid storage channel 211 and the accommodating chamber 124, thereby preventing the buffer from being oxidized and the sample from being contaminated. When the sealing plug 220 is connected to the liquid storage member 210, the connecting portion 222 will be over-set in the liquid storage channel 211, thereby blocking the part of the liquid storage channel 211 that does not accommodate the buffer, thereby preventing the buffer from leaking out of the liquid storage member 210 from the liquid storage channel 211, and also preventing external gas and impurities from entering the liquid storage channel 211. The limiting portion 221 is connected to the second end 2112 of the liquid storage member 210 and is connected to the connecting portion 222 . The connecting portion 222 enters and exits the liquid storage channel 211 through the limiting portion 221 .
[0065] In some embodiments (not shown in the figures), the sealing plug 220 may only include a limiting portion 221. The limiting portion 221 is connected to the second end 2112, and the limiting portion 221 covers the opening of the second end 2112 to close the second end 2112 of the liquid storage member 210. This can also prevent external gases and impurities from entering the liquid storage channel 211 and the accommodation cavity 124.
[0066] In some embodiments, referring to Figure 9 as shown, the sealing plug 220 is made of a visible material. Specifically, making the sealing plug 220 of a visible material can facilitate the operator to observe the buffer capacity in the liquid storage member 210 after injecting the buffer into the liquid storage member 210. In other embodiments (not shown in the figures), the sealing plug 220 may also be made of an invisible material. For example, when injecting the buffer into the liquid storage channel 211, the amount of the buffer can be set in advance and the duration that the injected buffer can be used can be estimated. When the predicted time value is reached, the sealing plug 220 is opened and the buffer is replenished into the liquid storage channel 211.
[0067] In other embodiments (not shown in the figures), the first cover body 110 and the base 400 may also be connected and fixed in other ways, such as: threaded connection, snap connection, or adhesive connection, etc. In other embodiments (not shown in the figures), the first cover body 110 and the base 400 may also be integrally formed.
[0068] Next, with reference to the accompanying drawings of the specification, the imaging device according to the second aspect embodiment of the present invention will be described.
[0069] The imaging device includes a microscope, the sample chamber described in any of the above embodiments, and a glass slide 600. The microscope includes a placement table for placing the sample chamber, and the glass slide 600 is placed in the accommodation cavity 124 of the sample chamber. Specifically, referring to Figures 1 to 11 as shown, when observing a sample, the sample needs to be first placed on the glass slide 600 and ensured that the sample is not contaminated. Secondly, the glass slide 600 is placed in the accommodation cavity 124, and the glass slide 600 is placed on the first support surface 111 of the first cover body 110. The glass slide 600 is fixed by the cooperation of the second cover body 120 and the first cover body 110. At the same time, the first cover body 110 and the second cover body 120 are fixed to place the entire main body member 100 on the base 400. Then, the buffer is injected into the accommodation cavity 124 through the liquid storage member 210, and the buffer is isolated from the external air through the sealing plug 220 to prevent the buffer from oxidizing and leaking. Finally, the sample chamber is fixed to the placement table to perform an imaging experiment on the sample.
[0070] Since the seal 300 is made of an elastic material, the seal 300 of the sample chamber can apply uniform pressure to the glass slide 600, thereby stably fixing the glass slide 600 and avoiding the situation where the movement of the glass slide 600 affects the sample observation result. At the same time, through the sealing plug 220 and the limiting portion 221, it is also possible to prevent the buffer solution from leaking, resulting in the corrosion of the microscope components and the oxidation reaction of the buffer solution, thereby improving the imaging quality and the accuracy of the experimental results and ensuring the imaging quality of the sample.
[0071] The embodiments of the present invention have been described in detail above with reference to the accompanying drawings. However, the present invention is not limited to the above embodiments. Within the scope of knowledge possessed by those of ordinary skill in the art, various changes can be made without departing from the gist of the present invention. In addition, the embodiments of the present invention and the features in the embodiments can be combined with each other without conflict.
Claims
1. Sample chamber, characterized in that, Comprising: A main body member, including a first cover body and a second cover body, the first cover body is connected to the second cover body, and a first support surface is provided on a side facing the second cover body. The second cover body has a hollow structure, and a convex portion is provided on a side facing the first cover body. The convex portion covers the first support surface and jointly defines a receiving cavity with the first support surface; A storage component, including a liquid storage member and a sealing plug. The liquid storage member passes through the hollow structure. The liquid storage member has a first end and a second end. A liquid storage channel communicating the first end and the second end is defined inside the liquid storage member. The first end is provided in the receiving cavity and communicates with the receiving cavity, and the second end is connected to the sealing plug; and A sealing member, provided in the receiving cavity, the sealing member is located between the convex portion and the liquid storage member, and is disposed around an outer wall surface of the first end.
2. The sample bin according to claim 1, characterized in that, It further includes a fastener. Through holes are provided in the first cover body and the second cover body, and the fastener passes through the through holes to connect and fix the first cover body and the second cover body.
3. The sample chamber according to claim 1, wherein The convex portion includes a fixing portion and a resisting portion. The resisting portion extends towards the first support surface relative to the fixing portion, and an accommodation groove is formed with the fixing portion. The sealing member is press-fitted in the accommodation groove.
4. The sample bin according to claim 3, characterized in that, The first cover body further includes a first abutting surface, which is recessed from a side of the first cover body facing the second cover body. The first abutting surface is connected to the first support surface, and the fixing portion is connected to the first abutting surface.
5. The sample bin according to claim 1, characterized in that, The sealing plug includes a limiting portion and a connecting portion. The limiting portion is connected to the connecting portion. The connecting portion extends from the sealing plug towards the liquid storage member. The connecting portion is accommodated in the liquid storage channel, and the limiting portion is provided at the second end.
6. The sample chamber according to claim 1, wherein The sealing plug is made of a visible material.
7. The sample chamber according to claim 1, characterized in that, It further includes a base, the base has an opposite upper side and a lower side. A support seat is recessed from the upper side towards the lower side. The support seat includes a second support surface and a second abutting surface, and the second support surface is connected to the second abutting surface.
8. The sample bin according to claim 7, wherein The first cover body is provided on the support seat. The second support surface is connected to the bottom of the first cover body, and the second abutting surface is connected to the side wall of the first cover body. The support seat is used to position the first cover body.
9. The sample chamber according to claim 8, characterized in that, Receiving holes are provided in the bottom of the first cover body and the second support surface. A magnetic member is accommodated in the receiving holes. The second support surface is detachably connected to the second support surface through the magnetic member.
10. An imaging device, characterized in that, Comprising: A microscope, including a placement table; The sample chamber according to any one of claims 1 to 9, connected to the placement table; A glass slide, accommodated in the receiving cavity.