Chromatographic column support structure

Abstract

The utility model discloses a chromatographic column bracket structure, which belongs to the field of chromatographic columns, solves the problem that the existing chromatographic column bracket cannot be suitable for chromatographic columns with different specifications, and comprises a base, fixed rods and a movable frame, the fixed rods are fixedly arranged on the upper surface of the base at equal intervals, and the movable frame is arranged on the side surfaces of the fixed rods. According to the utility model, the clamping mechanism is arranged, so that the chromatographic column can be quickly and stably mounted and positioned, the distance between the clamping piece and the extrusion plate can be adjusted according to the chromatographic columns with different specifications when the device is used, and the clamping piece can be used for clamping the chromatographic column main body, so that the chromatographic column main body can be quickly and stably positioned. The device is suitable for positioning and supporting chromatographic columns of different specifications, the distance between the liquid level height in the chromatographic column and an opening in the top end of the chromatographic column can be accurately marked when the device is used, an experimenter can conveniently supplement a buffer solution in the chromatographic column in time, and therefore the stability of the device in the using process is guaranteed.

Description

Technical Field

[0001] The utility model belongs to the field of chromatography columns, and particularly relates to a support structure for chromatography columns. Background Art

[0002] A chromatography column is the main body in gel chromatography technology, generally made of glass tubes or plexiglass tubes. According to the different distribution coefficients of each component in the sample mixture between the stationary phase and the mobile phase, a chromatography method for separation is adopted. It is a commonly used tool for gel and retrograde processing and detection. When in use, the chromatography column is generally installed on a corresponding support, and through the cooperation of the support, the position, height, and angle of the chromatography column itself are fixed, facilitating subsequent layering and detection.

[0003] Chinese Utility Model Patent CN204294259U discloses a chromatography column support, including: a loading platform and a platform support located on the horizontal ground to stably support the loading platform. The loading platform is a flat plate with uniform thickness and a number of loading holes. When in use, through the use of the loading holes, multiple groups of chromatography columns are installed and positioned, shortening the operation distance in the subsequent experiment process and improving the overall operation efficiency;

[0004] The above design can position and install multiple groups of chromatography columns simultaneously through the use and cooperation of multiple components. However, there are certain problems in actual use, specifically reflected in that chromatography columns are divided into various specifications according to their specifications. This device cannot cooperate with chromatography columns of different specifications for installation and positioning during use, resulting in an impact on the applicable range of the device itself. Summary of the Utility Model

[0005] The purpose of this part is to outline some aspects of the embodiments of the utility model and briefly introduce some preferred embodiments. Simplifications or omissions may be made in this part, as well as in the abstract of the specification and the title of the utility model of this application, to avoid obscuring the purpose of this part, the abstract of the specification, and the title of the utility model. Such simplifications or omissions shall not be used to limit the scope of the utility model.

[0006] To solve the problems raised in the above background art, the utility model adopts the following technical solutions.

[0007] A support structure for chromatography columns includes a base, a fixed rod, and a movable frame. Fixed rods are equidistantly and fixedly installed on the upper surface of the base. A movable frame is arranged on the side of the fixed rod. A clamping mechanism for assisting in positioning the chromatography column body is arranged on the side of the movable frame. An extrusion plate and a clamping member are arranged in the clamping mechanism, and the position of the chromatography column body is clamped by the extrusion plate and the clamping member.

[0008] As a preferred technical solution of the present utility model, the clamping mechanism includes an adjusting component, a pressing plate and a clamping member. The adjusting component is fixedly installed inside the moving frame, the pressing plate is slidably installed on the side of the moving frame, and the clamping member is fixedly installed on one side of the moving frame opposite to the pressing plate on the side.

[0009] As a preferred technical solution of the present utility model, the adjusting component includes a lead screw, a guide rod, a moving end and a rotating rod. The lead screw is rotatably installed inside the moving frame, the guide rod is fixedly installed inside the moving frame, the lead screw and the guide rod are parallel in position, the moving end is threadedly engaged and installed on the outer surface of the lead screw, the moving end is slidably connected to the guide rod, the rotating rod is rotatably installed on the side of the moving frame, the rotating rod is fixedly connected to the end of the lead screw, and the side of the moving end is fixedly connected to the end of the pressing plate.

[0010] As a preferred technical solution of the present utility model, the clamping member includes a clamping plate and a calibration plate. The clamping plate is fixedly installed on the side of the moving frame, a calibration groove is formed inside the clamping plate, and the calibration plate is slidably installed in the calibration groove.

[0011] As a preferred technical solution of the present utility model, the chromatography column support structure further includes a conveying mechanism. The conveying mechanism includes a support frame, an input component and a top cover. The support frame is fixedly installed on the upper surface of the moving frame, the input component is fixedly installed on the side of the support frame, and the top cover is arranged at the opening at the top of the input component.

[0012] As a preferred technical solution of the present utility model, the input component includes a storage bin, an output pipe, a feeding hose and a pressing rod. The storage bin is fixedly installed at the end of the support frame, the output pipe is fixedly installed at the bottom end of the storage bin, an output groove is formed inside the storage bin and the output pipe together, and the output groove penetrates through the output pipe. The feeding hose is fixedly installed in the output groove, the pressing rod is threadedly installed on the side of the output pipe, and the end of the pressing rod is in pressing contact with the outer surface of the feeding hose.

[0013] As a preferred technical solution of the present utility model, the moving frame includes a side shell, a fitting ring and a positioning rod. The side shell is arranged on the side of the fixed rod, the fitting ring is fixedly installed on the side of the side shell, the fitting ring is slidably connected to the outer surface of the fixed rod, the positioning rod is threadedly installed in the fitting ring, and the positioning rod penetrates through the side wall of the fitting ring.

[0014] Compared with the prior art, the beneficial effects of the present utility model are:

[0015] (1) In the present utility model, by providing a clamping mechanism, the chromatography column can be quickly and stably installed and positioned. During use, the distance between the clamping member and the pressing plate can be adjusted according to different specifications of the chromatography column, so that the device can adapt to different specifications of chromatography columns for positioning and support. Moreover, during use, the distance between the liquid level height in the chromatography column and the opening at the top of the chromatography column can be accurately marked, which is convenient for the experimenter to timely supplement the buffer solution in the chromatography column, thereby ensuring the stability of the device during use;

[0016] (2) In the present utility model, by providing a conveying mechanism and a moving frame, the overall height of the moving frame and the side components can be flexibly adjusted, which is convenient for adapting to chromatography columns of different lengths. Moreover, during subsequent use, the buffer solution can be centrally input into the storage bin and quickly and stably input into the chromatography column, eliminating the need for the staff to hold a dropper and repeatedly supplement the buffer solution, thereby improving the overall working efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 is a perspective view of the overall structure of the present utility model.

[0018] Figure 2 is a perspective view of the external structure of a single fixed rod of the present utility model.

[0019] Figure 3 is a perspective view of the structure of the clamping mechanism and the adjustment component of the present utility model.

[0020] Figure 4 is a schematic structural view of the clamping member in the present utility model.

[0021] Figure 5 is a schematic structural view of the conveying mechanism in the present utility model.

[0022] Figure 6 is a schematic structural view of the input component in the present utility model.

[0023] The corresponding relationship between the reference numerals and the component names in the drawings is as follows:

[0024] 1. Base; 2. Fixed rod; 3. Chromatography column main body; 4. Moving frame; 41. Side housing; 42. Fitting ring; 43. Positioning rod; 5. Clamping mechanism; 51. Adjustment component; 511. Lead screw; 512. Guide rod; 513. Mobile end; 514. Rotating rod; 52. Pressing plate; 53. Clamping member; 531. Clamping plate; 532. Calibration groove; 533. Calibration plate; 6. Conveying mechanism; 61. Support frame; 62. Input component; 621. Storage bin; 622. Output pipe; 623. Feeding hose; 624. Extrusion rod; 63. Top cover. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0025] In order to make the above-mentioned objects, features and advantages of the present utility model more obvious and understandable, the following will describe in detail the specific embodiments of the present utility model with reference to the accompanying drawings of the specification.

[0026] In the following description, many specific details are set forth in order to fully understand the present utility model. However, the present utility model can also be implemented in other ways different from those described herein. Those skilled in the art can make similar generalizations without departing from the connotation of the present utility model. Therefore, the present utility model is not limited by the specific embodiments disclosed below.

[0027] Secondly, the so-called "one embodiment" or "embodiment" herein refers to a specific feature, structure or characteristic that can be included in at least one implementation manner of the present utility model. The "in one embodiment" that appears in different places in this specification does not all refer to the same embodiment, nor is it a separate or selectively exclusive embodiment from other embodiments. The present utility model provides the following embodiments.

[0028] By Figure 1 and Figure 2 As shown, it is a schematic structural diagram of the overall chromatographic column support in this embodiment, including a base 1, a fixed rod 2 and a moving frame 4. Fixed rods 2 are equidistantly and fixedly installed on the upper surface of the base 1. A moving frame 4 is arranged on the side of the fixed rod 2. A clamping mechanism 5 for assisting in positioning the chromatographic column main body 3 is arranged on the side of the moving frame 4.

[0029] During use, the base 1 is installed on the side of the test bench. Then, under the use of the clamping mechanism 5, chromatographic columns of different specifications are clamped and positioned. Then, with the cooperation of the moving frame 4, the overall position of the moving frame 4 is adjusted according to the height of the chromatographic column itself, facilitating subsequent staff to fill and detect the materials inside the chromatographic column.

[0030] By the attached Figure 2 As shown, it is a schematic structural diagram of the clamping mechanism 5 in this embodiment. The clamping mechanism 5 includes an adjustment component 51, a pressing plate 52 and a clamping member 53. The adjustment component 51 is fixedly installed inside the moving frame 4. The pressing plate 52 is slidably installed on the side of the moving frame 4. The clamping member 53 is fixedly installed on the side of the moving frame 4 opposite to the pressing plate 52. During use, the chromatographic column main body 3 is placed between the pressing plate 52 and the clamping member 53. Then, under the use of the adjustment component 51, the pressing plate 52 stably moves towards the side close to the clamping member 53 until the pressing plate 52 and the clamping member 53 are attached to both side surfaces of the chromatographic column main body 3. Utilizing the convex structure at the top of the chromatographic column main body 3, the rapid installation and positioning of the chromatographic column main body 3 are completed.

[0031] By the attached Figure 3As shown, it is a schematic diagram of the structure of the adjustment component 51 in this embodiment, the adjustment component 51 includes a screw rod 511, a guide rod 512, a movable end 513 and a rotating rod 514, the screw rod 511 is rotatably installed inside the mobile frame 4, the guide rod 512 is fixedly installed inside the mobile frame 4, the screw rod 511 is parallel to the guide rod 512, the movable end 513 is threadedly engaged and installed on the outer surface of the screw rod 511, the movable end 513 is slidably connected to the guide rod 512, the rotating rod 514 is rotatably installed on the side of the mobile frame 4, and the rotating rod 51 4 is fixedly connected to the end of the screw rod 511, and the side of the movable end 513 is fixedly connected to the end of the extrusion plate 52. During use, by rotating the rotating rod 514, the rotating rod 514 drives the screw rod 511 to rotate stably inside the movable frame 4. By utilizing the cooperation between the thread on the outside of the screw rod 511 and the movable end 513, the movable end 513 drives the side extrusion plate 52 to slide toward the side close to the clamping member 53. When the extrusion plate 52 moves to the target position, the extrusion plate 52 and the clamping member 53 clamp the chromatography column body 3 at the middle end.

[0032] By the attached Figure 4 As shown, it is a structural schematic diagram of the clamping member 53 in this embodiment, the clamping member 53 includes a clamping plate 531 and a calibration plate 533, the clamping plate 531 is fixedly installed on the side of the mobile frame 4, a calibration groove 532 is opened inside the clamping plate 531, and the calibration plate 533 is slidably installed in the calibration groove 532. During use, the calibration plate 533 is inserted into the side of the clamping plate 531 through the calibration groove 532. During the subsequent installation of the chromatography column body 3, the top of the calibration plate 533 is fitted with the bottom surface of the protruding structure at the top of the chromatography column body 3. At this time, when observing the scale groove outside the calibration plate 533, the experimenter can accurately judge the distance between the liquid height inside the chromatography column body 3 and the top opening of the chromatography column body 3, which is convenient for the experimenter to adjust the liquid level height and the distance at the top opening of the chromatography column body 3 according to the different gel materials to be detected.

[0033] By the attached Figure 5 As shown, it is a structural schematic diagram of the conveying mechanism 6 in this embodiment, the chromatography column support structure also includes a conveying mechanism 6, the conveying mechanism 6 includes a support frame 61, an input component 62 and a top cover 63, the support frame 61 is fixedly mounted on the upper surface of the mobile frame 4, the input component 62 is fixedly mounted on the side of the support frame 61, and the top cover 63 is arranged at the top opening of the input component 62. During use, the top opening of the input component 62 is opened by shifting the top cover 63, and the buffer solution required for subsequent gel precipitation and processing is input into the input component 62. After that, through the use of the input component 62, the buffer solution inside the chromatography column body 3 is stably and accurately supplemented, and there is no need for the experimenter to hold a dropper to input the buffer solution.

[0034] By the attached Figure 6As shown, it is a schematic structural diagram of the input component 62 in this embodiment. The input component 62 includes a storage bin 621, an output pipe 622, a feeding hose 623, and a pressing rod 624. The storage bin 621 is fixedly installed at the end of the support frame 61, the output pipe 622 is fixedly installed at the bottom end of the storage bin 621. An output groove is jointly opened inside the storage bin 621 and the output pipe 622, and the output groove penetrates through the output pipe 622. The feeding hose 623 is fixedly installed in the output groove. The pressing rod 624 is threadedly installed on the side of the output pipe 622, and the end of the pressing rod 624 is in pressing contact with the outer surface of the feeding hose 623. During use, through the use of the storage bin 621, the subsequent input buffer solution is collected and stored. Then, by controlling the rotation direction of the pressing rod 624, the length of the pressing rod 624 passing through the side wall of the output pipe 622 is adjusted. Through the extrusion of the pressing rod 624, the opening and closing of the feeding hose 623 itself are controlled.

[0035] As shown in the attached Figure 4 As shown, it is a schematic structural diagram of the moving frame 4 in this embodiment. The moving frame 4 includes a side housing 41, a fitting ring 42, and a positioning rod 43. The side housing 41 is arranged on the side of the fixed rod 2. The fitting ring 42 is fixedly installed on the side of the side housing 41. The fitting ring 42 is slidably connected to the outer surface of the fixed rod 2. The positioning rod 43 is threadedly installed in the fitting ring 42, and the positioning rod 43 penetrates through the side wall of the fitting ring 42. During use, by pushing the fitting ring 42, the side housing 41 and the components on the side are driven by the fitting ring 42 to move vertically up and down along the fixed rod 2. When moving to the target position, by rotating the positioning rod 43, the position of the overall components of the moving frame 4 is fixed by the extrusion between the positioning rod 43 and the side of the fixed rod 2.

[0036] The above content further elaborates on the present invention in combination with specific embodiments. It cannot be determined that the specific implementation of the present invention is only limited to these descriptions. For those of ordinary skill in the technical field to which the present invention belongs, without departing from the concept of the present invention, several simple deductions or substitutions can still be made, which should all be regarded as falling within the protection scope determined by the claims submitted for the present invention.

Claims

1. A chromatography column support structure, comprising a base (1), a fixed rod (2) and a movable frame (4). The upper surface of the base (1) is equidistantly and fixedly provided with the fixed rod (2), and the movable frame (4) is arranged on the side of the fixed rod (2), characterized in that: A clamping mechanism (5) for assisting in positioning the chromatography column main body (3) is provided on the side of the moving frame (4). An extrusion plate (52) and a clamping member (53) are provided inside the clamping mechanism (5), and the position of the chromatography column main body (3) is clamped by the extrusion plate (52) and the clamping member (53).

2. The chromatographic column support structure according to claim 1, characterized in that: The clamping mechanism (5) includes an adjustment component (51), an extrusion plate (52) and a clamping member (53). The adjustment component (51) is fixedly installed inside the moving frame (4), the extrusion plate (52) is slidably installed on the side of the moving frame (4), and the clamping member (53) is fixedly installed on the side of the moving frame (4) opposite to the extrusion plate (52).

3. The chromatographic column support structure according to claim 2, wherein: The adjustment component (51) includes a lead screw (511), a guide rod (512), a moving end (513) and a rotating rod (514). The lead screw (511) is rotatably installed inside the moving frame (4), the guide rod (512) is fixedly installed inside the moving frame (4), the lead screw (511) and the guide rod (512) are parallel in position, the moving end (513) is threadedly engaged and installed on the outer surface of the lead screw (511), the moving end (513) is slidably connected to the guide rod (512), the rotating rod (514) is rotatably installed on the side of the moving frame (4), the rotating rod (514) is fixedly connected to the end of the lead screw (511), and the side of the moving end (513) is fixedly connected to the end of the extrusion plate (52).

4. A chromatography column support structure according to claim 3, characterized in that: The clamping member (53) includes a clamping plate (531) and a calibration plate (533). The clamping plate (531) is fixedly installed on the side of the moving frame (4), a calibration groove (532) is formed inside the clamping plate (531), and the calibration plate (533) is slidably installed in the calibration groove (532).

5. The chromatographic column support structure according to claim 1, wherein: The chromatography column support structure further includes a conveying mechanism (6). The conveying mechanism (6) includes a support frame (61), an input component (62) and a top cover (63). The support frame (61) is fixedly installed on the upper surface of the moving frame (4), the input component (62) is fixedly installed on the side of the support frame (61), and the top cover (63) is arranged at the top opening of the input component (62).

6. The chromatography column support structure according to claim 5, wherein: The input component (62) includes a storage bin (621), an output pipe (622), a feeding hose (623) and an extrusion rod (624). The storage bin (621) is fixedly installed at the end of the support frame (61), the output pipe (622) is fixedly installed at the bottom end of the storage bin (621), an output groove is formed inside the storage bin (621) and the output pipe (622) together, and the output groove penetrates through the output pipe (622). The feeding hose (623) is fixedly installed in the output groove, and the extrusion rod (624) is threadedly installed on the side of the output pipe (622), and the end of the extrusion rod (624) is in extrusion contact with the outer surface of the feeding hose (623).

7. A chromatography column support structure according to claim 1, characterized in that: The movable frame (4) includes a side housing (41), a fitting ring (42) and a positioning rod (43). The side housing (41) is arranged on the side of the fixed rod (2). The fitting ring (42) is fixedly installed on the side of the side housing (41). The fitting ring (42) is slidably connected to the outer surface of the fixed rod (2). The positioning rod (43) is threadedly installed in the fitting ring (42), and the positioning rod (43) penetrates through the side wall of the fitting ring (42).

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