Fluorescent PCR (Polymerase Chain Reaction) detection kit
By introducing fixing mechanisms such as clips and rotating plates into the fluorescent PCR detection kit, the problem of damage to the reagent tube during transportation is solved, and the stable fixation and convenient removal of the reagent tube is achieved.
Patent Information
- Application Number
- CN202422415207.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-30
- Publication Date
- 2025-07-25
- Estimated Expiration
- 2034-09-30
AI Technical Summary
The existing fluorescent PCR detection kits cannot effectively fix the reagent tube during transportation, resulting in damage to the reagent tube and the inner wall of the box.
A fixing mechanism including a clamp, a connecting rod, a trapezoidal block, a fixing rod, a return spring, a rotating plate and a limiting assembly is designed. By pressing the partition, the clamp clamps hold the reagent tube and the rotating rod is released to realize the stable storage and convenient removal of the reagent tube.
It effectively avoids collision and damage between the reagent tube and the inner wall of the box during transportation, ensuring the safety and convenience of the reagent tube.
Smart Images
Figure CN223149124U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the field of biochemical products, in particular to a fluorescence PCR detection kit. Background Art
[0002] In the field of biochemical product technology, fluorescence PCR detection reagents are a key tool for detecting specific nucleic acid sequences. They are usually a carefully designed and prepared combination of chemical reagents that can achieve specific amplification and detection of target nucleic acids during the PCR reaction. These reagents use changes in fluorescence signals to monitor the progress of the PCR reaction in real time and have the characteristics of high sensitivity and high specificity.
[0003] When transporting or carrying fluorescence PCR detection reagents, the reagents need to be placed in a kit for storage to facilitate transportation and carrying. In some existing technologies, the reagents cannot be well fixed inside the kit. During transportation, if the road conditions are bumpy and vibrate violently, the kit will keep shaking, causing the internal reagent tubes to constantly collide with the inner wall of the kit, which may lead to the rupture and damage of the reagent tubes. Therefore, a fluorescence PCR detection kit is proposed to solve the above problems. Summary of the Utility Model
[0004] The utility model aims at the technical problems existing in the prior art and provides a fluorescence PCR detection kit, which solves the problem that the existing kit cannot fix the reagent tubes and is prone to damage the reagent tubes.
[0005] The technical solution for the utility model to solve the above technical problems is as follows: a fluorescence PCR detection kit, including a placement box, and a fixing mechanism is arranged on the inner wall of the placement box;
[0006] The fixing mechanism includes clamping blocks, a connecting rod is fixedly connected to the outer wall of the clamping blocks, a trapezoidal block is slidably connected to the inner wall of the placement box, a fixing rod is fixedly connected to the outer wall of the bottom end of the trapezoidal block, a partition board is elastically connected to the inner wall of the bottom end of the placement box through a return spring, a convex block is fixedly connected to the outer wall of the partition board, a rotating plate is rotatably connected to the inner wall of the bottom end of the placement box, an inclined groove is arranged on the outer wall of the rotating plate, a fixing block is fixedly connected to the outer wall of the top end of the placement box, a rotating rod is elastically connected to the inner wall of the fixing block through a scroll spring, a limiting component is arranged on the inner wall of the placement box, and a reagent tube is in contact with the outer wall of the top end of the partition board.
[0007] Preferably, the clamping blocks are slidably connected to the inner wall of the placement box, the connecting rod is slidably connected to the outer wall of the trapezoidal block, and the fixing rod is fixedly connected to the outer wall of the partition board.
[0008] Preferably, one end of the spiral spring is fixedly connected to the inner wall of the fixed block, the other end of the spiral spring is fixedly connected to the outer wall of the rotating rod, the rotating rod is fixedly connected to the rotating plate, and the rotating rod is rotatably connected to the inner wall of the placement box.
[0009] Preferably, one end of the return spring is fixedly connected to the outer wall of the bottom end of the partition, the other end of the return spring is fixedly connected to the inner wall of the bottom end of the placement box, and the partition is slidably connected to the inner wall of the placement box.
[0010] Preferably, the limiting assembly comprises a wedge block, the wedge block is elastically connected to the inner wall of the placement box via a connecting spring, and a sliding rod is fixedly connected to the outer wall of the bottom end of the wedge block.
[0011] Preferably, one end of the connecting spring is fixedly connected to the outer wall of the wedge, and the other end of the connecting spring is fixedly connected to the inner wall of the placement box.
[0012] Preferably, the outer wall of the wedge block is slidably connected to the inner wall of the placement box, the sliding rod is slidably connected to the inner wall of the inclined groove, and the wedge block contacts the outer wall of the protrusion.
[0013] The beneficial effect of the utility model is that by placing the reagent tube in the cavity in the placement box and pressing downward to move the partition downward, the three groups of clamps can be driven to move toward the middle at the same time, and the partition is limited by the wedge block to fix the three groups of clamps to clamp and fix the reagent tube, and by rotating the rotating rod, the three groups of clamps can be disengaged from the reagent tube by rotating the rotating plate, and the fixation of multiple groups of reagent tubes can be released at the same time, thereby avoiding the problem of internal reagent tubes contacting and colliding with the inner wall of the reagent kit to cause damage when the box is transported or placed. BRIEF DESCRIPTION OF THE DRAWINGS
[0014] Figure 1 This is a schematic diagram of the main structure of the utility model;
[0015] Figure 2 This is a schematic diagram of the cross-sectional structure of the placement box and the fixing block of the utility model;
[0016] Figure 3 This is a schematic diagram of the cross section of the placement box and the fixing mechanism structure of the utility model;
[0017] Figure 4 This is a schematic diagram of the cross section of the placement box and the wedge structure of the utility model;
[0018] Figure 5 It is a schematic diagram of the fixing mechanism structure of the utility model.
[0019] In the accompanying drawings, the components represented by the reference numerals are listed as follows:
[0020] 1. Placement box; 2. Fixing mechanism; 201. Clamping block; 202. Connecting rod; 203. Trapezoidal block; 204. Fixed rod; 205. Partition board; 206. Return spring; 207. Rotating plate; 208. Inclined groove; 209. Volute spring; 210. Rotating rod; 211. Fixed block; 212. Convex block; 2001. Connecting spring; 2002. Wedge block; 2003. Sliding rod; 3. Reagent tube. Detailed implementation manners
[0021] Next, the technical solutions in the embodiments of the present application will be clearly and completely described with reference to the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative efforts shall fall within the protection scope of the present application.
[0022] In the description of the present application, the terms "first" and "second" are only used for descriptive purposes, and cannot be construed as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include one or more of the described features. In the description of the present application, "a plurality" means two or more, unless otherwise specifically defined.
[0023] In the description of the present application, the term "for example" is used to mean "serving as an example, illustration, or explanation". Any embodiment described as "for example" in the present application is not necessarily construed as being more preferred or having more advantages than other embodiments. In order for any person skilled in the art to implement and use the present invention, the following description is given. In the following description, details are set forth for the purpose of explanation. It should be understood that those skilled in the art can recognize that the present invention can be implemented without using these specific details. In other instances, well-known structures and processes are not described in detail to avoid unnecessary details from obscuring the description of the present invention. Therefore, the present invention is not intended to be limited to the embodiments shown, but is to be accorded the widest scope consistent with the principles and features disclosed in the present application.
[0024] Embodiment 1
[0025] As Figures 1 to 5As shown in the figure, the utility model provides a fluorescence PCR detection kit, which includes a placement box 1, and a fixing mechanism 2 is arranged on the inner wall of the placement box 1; the fixing mechanism 2 includes a clamping block 201, a connecting rod 202 is fixedly connected to the outer wall of the clamping block 201, a trapezoidal block 203 is slidably connected to the inner wall of the placement box 1, a fixing rod 204 is fixedly connected to the outer wall of the bottom end of the trapezoidal block 203, a partition plate 205 is elastically connected to the inner wall of the bottom end of the placement box 1 through a return spring 206, a convex block 212 is fixedly connected to the outer wall of the partition plate 205, a rotating plate 207 is rotatably connected to the inner wall of the bottom end of the placement box 1, an inclined groove 208 is opened on the outer wall of the rotating plate 207, a fixing block 211 is fixedly connected to the outer wall of the top end of the placement box 1, a rotating rod 210 is elastically connected to the inner wall of the fixing block 211 through a scroll spring 209, and a limiting component is arranged on the inner wall of the placement box 1, and a reagent tube 3 is in contact with the outer wall of the top end of the partition plate 205.
[0026] Adopting the above scheme: The placement box 1 is the main body of the fluorescence PCR detection kit, which is an existing technology. Multiple cavities are opened in the placement box 1, and the reagent tubes 3 can be placed and stored in the cavities, and the reagent tubes 3 are fixed by the fixing mechanism 2; three clamping blocks 201 are arranged in each cavity, which can contact the outer wall of the reagent tube 3 from three directions to keep it in a fixed state, so as to avoid the problem that the reagent tube 3 is damaged due to shaking during transportation; when multiple reagent tubes 3 are all placed in the cavities, multiple reagent tubes 3 can be pressed simultaneously, so that multiple reagent tubes 3 can be clamped and fixed at the same time, which is more convenient; and by rotating the rotating rod 210, the clamping states of multiple reagent tubes 3 can be released simultaneously, and the reagent tubes 3 can be taken out.
[0027] As Figures 2 to 5 shown in the figure, the clamping block 201 is slidably connected to the inner wall of the placement box 1, the connecting rod 202 is slidably connected to the outer wall of the trapezoidal block 203, and the fixing rod 204 is fixedly connected to the outer wall of the partition plate 205; one end of the scroll spring 209 is fixedly connected to the inner wall of the fixing block 211, the other end of the scroll spring 209 is fixedly connected to the outer wall of the rotating rod 210, the rotating rod 210 is fixedly connected to the rotating plate 207, and the rotating rod 210 is rotatably connected to the inner wall of the placement box 1; one end of the return spring 206 is fixedly connected to the outer wall of the bottom end of the partition plate 205, the other end of the return spring 206 is fixedly connected to the inner wall of the bottom end of the placement box 1, and the partition plate 205 is slidably connected to the inner wall of the placement box 1.
[0028] Adopting the above scheme: Without the influence of external force, the return spring 206 drives the partition plate 205 to move upward due to its own elastic force, so that the fixing rod 204 and the trapezoidal block 203 move upward synchronously. In this state, the connecting rod 202 keeps contacting the bottom edge of the inclined surface of the trapezoidal block 203 and drives the clamping block 201 to remain in the inner wall of the placement box 1, and the clamping block 201 is not inside the cavity of the placement box 1, as Figure 2As shown in the figure; when the reagent tube 3 is placed on the partition plate 205 in the cavity, the reagent tube 3 can be pressed downward, and the partition plate 205 will move downward accordingly. The return spring 206 is stressed and contracts. While the partition plate 205 moves downward, the fixed rod 204 and the trapezoidal block 203 move downward synchronously. The inclined surface of the trapezoidal block 203 squeezes the connecting rod 202, so that the three groups of connecting rods 202 drive the corresponding clamping blocks 201 to move towards the middle at the same time and fit against the outer wall of the reagent tube 3 at the same time, then the reagent tube 3 can be clamped; then, through the limit component to limit the partition plate 205, the partition plate 205, the fixed rod 204, the trapezoidal block 203, the connecting rod 202 and the clamping block 201 are all kept in a fixed state, so as to maintain the fixing effect on the reagent tube 3, which is more convenient and also avoids the problem that the reagent tube 3 shakes and collides with the inner wall of the reagent kit and causes damage during transportation or when being collided.
[0029] Embodiment 2
[0030] The limit component includes a wedge block 2002, which is elastically connected to the inner wall of the placement box 1 through a connecting spring 2001. A sliding rod 2003 is fixedly connected to the outer wall of the bottom end of the wedge block 2002; one end of the connecting spring 2001 is fixedly connected to the outer wall of the wedge block 2002, and the other end of the connecting spring 2001 is fixedly connected to the inner wall of the placement box 1; the outer wall of the wedge block 2002 is slidably connected to the inner wall of the placement box 1, the sliding rod 2003 is slidably connected to the inner wall of the inclined groove 208, and the outer wall of the wedge block 2002 is in contact with the outer wall of the convex block 212.
[0031] Adopting the above scheme: the arc surface of the wedge block 2002 keeps upward. In the case where the reagent tube 3 is not placed in the placement box 1, the wedge block 2002 is located below the partition plate 205. When the partition plate 205 moves downward, the convex block 212 on its outer wall generates a squeezing force on the arc surface of the wedge block 2002, so that the wedge block 2002 moves horizontally and inwards along the inner wall of the placement box 1, and the connecting spring 2001 is stressed and contracts; when the partition plate 205 moves downward until the three groups of clamping blocks 201 are in contact with the outer wall of the reagent tube 3, the convex block 212 is located below the wedge block 2002 and is separated from the outer wall of the wedge block 2002. At this time, the connecting spring 2001 makes the wedge block 2002 move horizontally and reset due to its own elastic force. The straight surface of the wedge block 2002 is in contact with the top outer wall of the convex block 212, so as to limit the convex block 212 and fix the position of the partition plate 205, thereby maintaining the clamping and fixing state of the reagent tube 3.
[0032] When it is necessary to take out the reagent tube 3, the rotating rod 210 can be rotated to make the scroll spring 209 contract under force, driving the rotating plate 207 to rotate synchronously. The inclined groove 208 squeezes the outer wall of the sliding rod 2003, causing the sliding rod 2003 to move. Since the sliding rod 2003 is in contact with the sliding groove in the placement box 1, the sliding groove can guide the sliding rod 2003. Therefore, when the rotating plate 207 rotates, multiple groups of sliding rods 2003 can move outward synchronously, driving the corresponding wedge blocks 2002 to move synchronously until they are disengaged from the convex blocks 212, releasing the limit on the partition plate 205. Under the elastic force of the return spring 206, the partition plate 205 moves upward to reset, causing the trapezoidal block 203 to move upward synchronously, driving the three connecting rods 202 and the clamping blocks 201 to move outward simultaneously and disengage from the outer wall of the reagent tube 3, thus releasing the fixation of the reagent tube 3 and taking it out. At this time, the rotating rod 210 can be released. Under the elastic force of the scroll spring 209, the rotating rod 210 rotates in the reverse direction and drives the rotating plate 207 to rotate synchronously, causing the wedge block 2002 to reset and be located below the convex block 212. Therefore, it is not only convenient to fix the reagent tube 3, and pressing down can complete the fixation. When taking out the reagent tube 3, the fixation of multiple groups of reagent tubes 3 can be released simultaneously, which is convenient for taking.
[0033] The working principle and usage process of the present utility model:
[0034] The operator can place the reagent tube 3 on the partition plate 205 in the placement box 1 and press the reagent tube 3 downward, causing the partition plate 205 to move downward. The return spring 206 contracts under force, driving the fixed rod 204 and the trapezoidal block 203 to move downward synchronously. The inclined surface of the trapezoidal block 203 squeezes the connecting rod 202, causing the three connecting rods 202 to drive the corresponding clamping blocks 201 to move inward simultaneously. When the clamping blocks 201 are in contact with the outer wall of the reagent tube 3, the reagent tube 3 can be clamped.
[0035] During the process of the partition plate 205 moving downward, the convex block 212 on the outer wall of the partition plate 205 exerts a squeezing force on the arc surface of the wedge block 2002, causing the wedge block 2002 to move horizontally inward along the inner wall of the placement box 1, and the connecting spring 2001 contracts under force. When the partition plate 205 moves downward until the three clamping blocks 201 are in close contact with the outer wall of the reagent tube 3, the convex block 212 is located below the wedge block 2002 and disengages from the outer wall of the wedge block 2002. At this time, the connecting spring 2001 moves the wedge block 2002 horizontally and resets due to its own elastic force. The straight surface of the wedge block 2002 contacts the top outer wall of the convex block 212 to limit the convex block 212, fixing the position of the partition plate 205, thereby maintaining the clamped and fixed state of the reagent tube 3 and preventing the reagent tube 3 from shaking and colliding with the inner wall of the reagent kit and being damaged during transportation or when being collided.
[0036] When it is necessary to take out the reagent tube 3, the rotating rod 210 can be rotated to make the scroll spring 209 contract under force, driving the rotating plate 207 to rotate synchronously. Multiple inclined grooves 208 on the rotating plate 207 extrude the outer walls of the sliding rods 2003, so that the multiple sliding rods 2003 can move outward synchronously, driving the corresponding wedges 2002 to move synchronously until they are disengaged from the convex blocks 212, releasing the limit of the partition plate 205. Under the elastic force of the return spring 206, the partition plate 205 moves upward to reset, causing the trapezoidal block 203 to move upward synchronously, driving the three connecting rods 202 and the clamping blocks 201 to move outward simultaneously and disengage from the outer wall of the reagent tube 3, releasing the fixation of the reagent tube 3. Thus, the limits of multiple reagent tubes 3 can be conveniently and quickly released at the same time, and the reagent tube 3 can be taken out. Moreover, after the rotating rod 210 is released, under the elastic force of the scroll spring 209, the rotating rod 210 rotates in the reverse direction and drives the rotating plate 207 to rotate synchronously, causing the wedge 2002 to reset and be located below the convex block 212, preparing for the next placement of the reagent tube 3.
[0037] It should be noted that in the above embodiments, the descriptions of each embodiment have their own emphases. For the parts not described in detail in a certain embodiment, reference can be made to the relevant descriptions of other embodiments.
[0038] Although the preferred embodiments of the present invention have been described, those skilled in the art can make additional changes and modifications once they know the basic creative concept. Therefore, the appended claims are intended to be construed as including the preferred embodiments and all changes and modifications falling within the scope of the present invention.
[0039] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalent technologies, the present invention is also intended to include these modifications and variations.
Claims
1. A fluorescence PCR detection kit, comprising a placement box (1), characterized in that: The inner wall of the placement box (1) is provided with a fixing mechanism (2); The fixing mechanism (2) includes clamping blocks (201). The outer wall of the clamping block (201) is fixedly connected with a connecting rod (202). A trapezoidal block (203) is slidably connected to the inner wall of the placement box (1). The bottom outer wall of the trapezoidal block (203) is fixedly connected with a fixing rod (204). The bottom inner wall of the placement box (1) is elastically connected with a partition plate (205) through a return spring (206). The outer wall of the partition plate (205) is fixedly connected with a convex block (212). The bottom inner wall of the placement box (1) is rotatably connected with a rotating plate (207). An inclined groove (208) is formed in the outer wall of the rotating plate (207). The top outer wall of the placement box (1) is fixedly connected with a fixing block (211). A rotating rod (210) is elastically connected to the inner wall of the fixing block (211) through a scroll spring (209). A limiting component is arranged on the inner wall of the placement box (1). The top outer wall of the partition plate (205) contacts a reagent tube (3).
2. The fluorescent PCR detection kit according to claim 1, wherein: The clamping block (201) is slidably connected to the inner wall of the placement box (1). The connecting rod (202) is slidably connected to the outer wall of the trapezoidal block (203). The fixing rod (204) is fixedly connected to the outer wall of the partition plate (205).
3. The fluorescence PCR detection kit according to claim 1, wherein: One end of the scroll spring (209) is fixedly connected to the inner wall of the fixing block (211). The other end of the scroll spring (209) is fixedly connected to the outer wall of the rotating rod (210). The rotating rod (210) is fixedly connected to the rotating plate (207). The rotating rod (210) is rotatably connected to the inner wall of the placement box (1).
4. The fluorescence PCR detection kit according to claim 1, wherein: One end of the return spring (206) is fixedly connected to the bottom outer wall of the partition plate (205). The other end of the return spring (206) is fixedly connected to the bottom inner wall of the placement box (1). The partition plate (205) is slidably connected to the inner wall of the placement box (1).
5. The fluorescent PCR detection kit according to claim 1, wherein: The limiting component includes a wedge block (2002). The wedge block (2002) is elastically connected to the inner wall of the placement box (1) through a connecting spring (2001). The bottom outer wall of the wedge block (2002) is fixedly connected with a sliding rod (2003).
6. The fluorescence PCR detection kit according to claim 5, wherein: One end of the connecting spring (2001) is fixedly connected to the outer wall of the wedge block (2002). The other end of the connecting spring (2001) is fixedly connected to the inner wall of the placement box (1).
7. The fluorescence PCR detection kit according to claim 5, characterized in that: The outer wall of the wedge block (2002) is slidably connected to the inner wall of the placement box (1). The sliding rod (2003) is slidably connected to the inner wall of the inclined groove (208). The outer wall of the wedge block (2002) contacts the outer wall of the convex block (212).