Hot cover structure of portable nucleic acid amplification analyzer

Through the improved thermal cover structure, the use of elastic components and hidden wiring design, the problem of reaction liquid gasification caused by bottom heating is solved, which improves the experimental success rate and operation convenience and reduces costs.

CN223150543UActive Publication Date: 2025-07-25BEIJING FANZHI MEDICAL TECH CO LTD
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Patent Information

Application Number
CN202422261639.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-14
Publication Date
2025-07-25
Estimated Expiration
2034-09-14

AI Technical Summary

Technical Problem

The bottom heating method of the existing nucleic acid amplification analyzer causes the reaction liquid in the PCR tube to vaporize, forming water mist or water droplets, affecting the success rate of the experiment. Moreover, the elastic components of the traditional heat cover structure are single, which cannot effectively prevent the reaction liquid from overflowing.

Method used

The heat cover structure is adopted where the upper shell and the lower shell are threaded, and the elastic components and heating components are installed inside, including circuit boards and heating elements. The elastic components are used to displace the heating components in the vertical direction, and conduct heat through a silicone pad, combined with a hidden wiring design to prevent the reaction liquid from overflowing.

Benefits of technology

It improves the experiment success rate, prevents reaction liquid from overflowing, reduces costs, and achieves better heating effect and operational convenience.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a hot cover structure of a portable nucleic acid amplification analyzer, which comprises an upper shell and a lower shell in threaded connection with the upper shell, an elastic component and a heating component are sequentially arranged between the upper shell and the lower shell, the upper shell is fixedly provided with a fixed seat, a screw hole is arranged in the fixed seat, the lower shell is provided with a lower shell through groove, and the lower shell is provided with a counterbore at a position corresponding to the screw hole. The upper shell and the lower shell are in threaded connection through the screw holes and the counterbores, the heating assembly comprises a circuit board, a heating element arranged on the side, close to the lower shell, of the circuit board and a heating plate attached to the heating element, the shape of the heating plate corresponds to the shape of the through groove of the lower shell, and an avoiding hole is formed in the position, corresponding to the fixing base, of the circuit board; the diameter of the avoiding hole is larger than that of the fixing base, the elastic assembly is used for enabling the heating assembly to generate relative displacement in the vertical direction, and the device has the advantages of being high in experiment success rate, convenient to operate and lower in cost.
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Description

Technical Field

[0001] The utility model relates to the technical field of in vitro diagnostic equipment, in particular to a thermal cover structure of a portable nucleic acid amplification analyzer. Background Technique

[0002] During the experiment process of the nucleic acid amplification analyzer, it is necessary to heat the PCR tube. The current heating method is to heat the bottom of the PCR tube. However, bottom heating will cause the reaction solution in the PCR tube to vaporize at high temperature, and the gas will condense on the tube wall or the top cover to form water mist or water droplets. The water mist or water droplets will directly escape from the air gap of the tube cover or the film, resulting in a reduction in the amount of the reaction solution, a change in the concentration of the reaction solution, and ultimately leading to the failure of the experiment. Content of the Utility Model

[0003] In order to overcome the deficiencies of the prior art, the purpose of the utility model is to provide a thermal cover structure of a portable nucleic acid amplification analyzer, which has the advantages of high experimental success rate, convenient operation, and lower cost.

[0004] To achieve the above purpose, the utility model provides the following technical solutions:

[0005] A thermal cover structure of a portable nucleic acid amplification analyzer includes an upper shell, a lower shell threadedly connected to the upper shell, and an elastic component and a heating component sequentially arranged between the upper shell and the lower shell;

[0006] A fixing seat is fixedly arranged on the upper shell, and a screw hole is arranged inside the fixing seat;

[0007] The lower shell is provided with a lower shell through groove, a counterbore is arranged at a position corresponding to the screw hole on the lower shell, and the upper shell and the lower shell are threadedly connected through the screw hole and the counterbore;

[0008] The heating component includes a circuit board, a heating element arranged on one side of the circuit board close to the lower shell, and a heating plate attached to the heating element. The shape of the heating plate corresponds to the shape of the lower shell through groove. An avoidance hole is arranged at a position corresponding to the fixing seat on the circuit board, and the diameter of the avoidance hole is larger than the diameter of the fixing seat;

[0009] The elastic component is used to cause the heating component to generate relative displacement in the vertical direction.

[0010] Further, the elastic component includes a positioning seat arranged inside the top of the upper shell, a positioning seat hole is arranged inside the positioning seat, a positioning pin is inserted into the positioning seat hole, a spring is sleeved on the positioning pin, a positioning hole is arranged at a position corresponding to the positioning seat hole on the circuit board, and the diameters of the positioning seat hole and the positioning hole match the diameter of the positioning pin.

[0011] Further, the elastic component includes an elastic plate and connecting ribs fixedly arranged inside the top of the upper cover. The shape formed by the middle part of the connecting ribs matches the shape of the elastic plate.

[0012] Further, the circumferential clearance between the positioning pin and the positioning hole on the circuit board is 0.1 mm - 0.2 mm.

[0013] Further, the elastic plate is made of silica gel foam material.

[0014] Further, the heating plate has a concentric circular boss structure, and the height of the boss is greater than the maximum displacement that the elastic component can vertically move.

[0015] Further, a groove is provided on the side of the heating plate close to the circuit board, a silica gel pad is provided in the groove, the shape of the groove matches the shape of the silica gel pad, and the silica gel pad is in contact connection with the heating element for heat conduction.

[0016] Further, the heating element is a heating resistor.

[0017] Further, an upper shell connecting piece is provided at one side edge of the upper shell, a clamping groove is provided on the upper shell connecting piece, a lower shell connecting piece is provided at the edge of the lower shell far from the heating component, the shape of the lower shell connecting piece matches the shape of the clamping groove, and the upper shell connecting piece and the lower shell connecting piece are inserted into each other through the clamping groove.

[0018] Further, the lower shell further includes a lower cover groove provided at a position opposite to the lower shell connecting piece.

[0019] Compared with the prior art, the beneficial effects of the present utility model are as follows:

[0020] 1. By providing a heating component, the problem that the experiment is likely to fail due to bottom heating is solved, and it has the advantages of upper cover heating and high experiment success rate;

[0021] 2. By providing an elastic component, the problem that the reaction liquid is likely to overflow is solved, and it has the advantage of pressing the PCR tube with an elastic material;

[0022] 3. By setting the elastic component as a spring or a silica gel foam board, the problem that the traditional hot cover structure has only a single type of elastic component is solved, and it has the advantage of being able to select different elastic components according to needs;

[0023] 4. By setting the circumferential clearance between the positioning pin and the positioning hole on the circuit board to be 0.1 mm - 0.2 mm, the problem of uneven sliding during use is solved, and it has the advantage of smooth sliding;

[0024] 5. By providing a heating resistor, the problem that the circuit board has a poor heating effect on the heating plate is solved, and it has the advantages of better heating effect, light weight, and lower cost;

[0025] 6. By assembling the upper shell and the lower shell, a cavity structure is formed between the upper shell and the lower shell for accommodating the circuits of the heating plate and the circuit board, and the problem of exposed circuits is solved, and it has the advantage of hidden wiring. Description of the Drawings

[0026] Figure 1 Schematic diagram of the three-dimensional explosion structure of the present utility model;

[0027] Figure 2 Schematic diagram of the three-dimensional explosion structure of the present utility model;

[0028] Figure 3 Schematic diagram of the three-dimensional structure of the upper shell of Embodiment 1 of the present utility model;

[0029] Figure 4 Schematic diagram of the bottom view structure of the circuit board of the present utility model;

[0030] Figure 5 Schematic diagram of the top view structure and the sectional view at position B of the heating plate of the present utility model, where a is the top view structure of the heating plate and b is the sectional view at position B;

[0031] Figure 6 Schematic diagram of the three-dimensional structure of the lower shell of the present utility model;

[0032] Figure 7 Schematic diagram of the bottom view structure and the sectional view at position A of Embodiment 1 of the present utility model, where a is the bottom view structure and b is the sectional view at position A;

[0033] Figure 8 Schematic diagram of the bottom view structure of the upper shell of Embodiment 2 of the present utility model;

[0034] Figure 9 Schematic diagram of the bottom view structure of the elastic plate of Embodiment 2 of the present utility model;

[0035] Figure 10 Schematic diagram of the bottom view structure and the sectional view at position C of Embodiment 2 of the present utility model, where a is the bottom view structure and b is the sectional view at position C;

[0036] Figure 11 Schematic diagram of the three-dimensional structure during the use of the present utility model;

[0037] In the figure: 100, upper shell; 110, fixed seat; 111, screw hole; 120, upper shell connecting member; 121, engaging groove; 200, lower shell; 210, lower shell through groove; 220, counterbore; 230, lower shell connecting member; 240, lower cover groove; 300, elastic component; 310, positioning seat; 311, positioning seat hole; 320, positioning pin; 330, spring; 340, positioning hole; 350, elastic plate; 351, connecting rib; 400, heating component; 410, circuit board; 411, heating element; 412, avoidance hole; 420, heating plate; 421, groove; 430, silica gel pad. Detailed implementation manners

[0038] Next, the technical solutions in the embodiments of the present utility model will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present utility model. Obviously, the described embodiments are only a part of the embodiments of the present utility model, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present utility model without making creative efforts shall fall within the protection scope of the present utility model.

[0039] Embodiment 1:

[0040] Please refer to Figures 1-7 , this embodiment provides a thermal cover structure of a portable nucleic acid amplification analyzer, including an upper shell 100, a lower shell 200 threadedly connected to the upper shell 100, an elastic component 300 and a heating component 400 are sequentially arranged between the upper shell 100 and the lower shell 200;

[0041] A fixed seat 110 is fixedly arranged on the upper shell 100, and a screw hole 111 is arranged in the fixed seat 110. In this embodiment, the fixed seat 110 is arranged at the four corners inside the bottom of the upper shell 100;

[0042] The lower shell 200 is provided with a lower shell through groove 210, and a counterbore 220 is arranged at a position corresponding to the screw hole 111 of the lower shell 200. The upper shell 100 and the lower shell 200 are threadedly connected through the screw hole 111 and the counterbore 220;

[0043] The heating component 400 includes a circuit board 410, a heating element 411 arranged on one side of the circuit board 410 close to the lower shell 200, and a heating plate 420 attached to the heating element 411. The shape of the heating plate 420 corresponds to the shape of the lower shell through groove 210. An avoidance hole 412 is arranged at a position corresponding to the fixed seat 110 on the circuit board 410, and the diameter of the avoidance hole 412 is larger than the diameter of the fixed seat 110;

[0044] The elastic component 300 is used to cause the heating component 400 to generate a relative displacement in the vertical direction;

[0045] In this embodiment, the heating plate 420 can be made of materials with good thermal conductivity such as aluminum or copper;

[0046] It can be understood that after the circuit board 410 and the heating plate 420 are fixed with bolts, the circuit board 410 and the heating plate 420 are integrally placed into the upper shell 100 equipped with the elastic component 300. When the heating plate 420 moves upward towards the upper cover 100, the fixed seat 110 can just pass through the avoidance hole 412. Then, the counterbore 220 of the lower shell 200 is aligned with the screw hole 111 of the fixed seat 110, and the upper shell 100 and the lower shell 200 are fixed with bolts, and the assembly is completed.

[0047] In this embodiment, the elastic component 300 includes a positioning seat 310 arranged inside the top of the upper shell 100. A positioning seat hole 311 is arranged in the positioning seat 310. A positioning pin 320 is inserted into the positioning seat hole 311. A spring 330 is sleeved on the positioning pin 320. A positioning hole 340 is arranged at a position corresponding to the positioning seat hole 311 on the circuit board 410. The diameters of the positioning seat hole 311 and the positioning hole 340 are matched with the diameter of the positioning pin 320.

[0048] It can be understood that both ends of the positioning pin 320 are inserted into the positioning hole 340 and the positioning seat hole 311. The spring 330 is arranged between the circuit board 410 and the positioning seat 310. The positioning pin 320 passes through the center of the spring 330.

[0049] In this embodiment, the circumferential clearance between the positioning pin 320 and the positioning hole 340 on the circuit board 410 is 0.1 mm - 0.2 mm;

[0050] It can be understood that when the positioning pin 320 is inserted into the positioning seat hole 311, the positioning pin 320 is fixed in the positioning seat hole 311. When the positioning pin 320 is inserted into the positioning hole 340 of the circuit board 410, there is a circumferential clearance of 0.1 mm - 0.2 mm between the positioning pin 320 and the positioning hole 340, which can ensure that when the heating plate 420 moves in the direction of the upper cover 100, the positioning pin 320 slides smoothly on the circuit board 410.

[0051] In this embodiment, the heating plate 420 is a concentric circular boss structure, and the height of the boss is greater than the maximum displacement that the elastic component 300 can vertically move;

[0052] It can be understood that when the heating plate 420 moves in the direction of the upper cover 100, the heating plate 420 will not separate from the lower shell 200. When the heating plate 420 moves in the direction of the lower shell 200, the heating plate 420 will not be stuck at the through groove 210 of the lower shell.

[0053] In this embodiment, a groove 421 is arranged on one side of the heating plate 420 close to the circuit board 410. A silica gel pad 430 is arranged in the groove 421. The shape of the groove 421 is matched with that of the silica gel pad 430. The silica gel pad 430 is in contact connection with the heating element 411 for heat conduction;

[0054] It can be understood that the silica gel pad 430 is arranged between the heating plate 420 and the component 411, playing a role in heat conduction and improving the heat conduction efficiency.

[0055] In this embodiment, the heating element 411 is a heating resistor; it can be understood that the heating resistor has better heating effect, is lighter, and has lower cost.

[0056] In this embodiment, an upper shell connector 120 is provided at one edge of the upper shell 100. The upper shell connector 120 is provided with a clamping groove 121. A lower shell connector 230 is provided at one edge of the lower shell 200 away from the heating component 400. The shape of the lower shell connector 230 matches the shape of the clamping groove 121. The upper shell connector 120 and the lower shell connector 230 are inserted into each other through the clamping groove 121.

[0057] It can be understood that after the upper shell connector 120 and the lower shell connector 230 are assembled, a cavity structure is formed between the upper shell 100 and the lower shell 200. The cavity structure is used to accommodate the heating plate 420 and the circuit of the circuit board 410, achieving the effect of hidden wiring.

[0058] In this embodiment, the lower shell 200 further includes a lower cover groove 240 provided at a position opposite to the lower shell connector 230; the cover groove 240 is used to engage with another part of the nucleic acid amplification analyzer during use.

[0059] Embodiment 2:

[0060] Please refer to Figures 8-10 , the difference between this embodiment and Embodiment 1 is that the elastic component 300 includes an elastic plate 350, and connecting ribs 351 fixedly arranged on the inner side of the top of the upper cover 100. The shape formed by the middle part of the connecting ribs 351 matches the elastic plate 350;

[0061] In this embodiment, the elastic plate 350 is made of silica gel foam material.

[0062] During use, please refer to Figure 11 , the shape of the thermal cover structure matches the portable nucleic acid amplification analyzer. Hinge the assembled thermal cover structure with the connecting component on the side of the base of the portable nucleic acid amplification analyzer, close the thermal cover structure, and turn on the power of the portable nucleic acid amplification analyzer to conduct experiments.

[0063] The above are only the preferred embodiments of the present invention and are not used to limit the present invention. For those skilled in the art, the present invention can have various changes and modifications. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included within the protection scope of the present invention.

Claims

1. The thermal cover structure of a portable nucleic acid amplification analyzer, characterized in that: It includes an upper shell (100), a lower shell (200) threadedly connected to the upper shell (100), an elastic component (300) and a heating component (400) sequentially arranged between the upper shell (100) and the lower shell (200); A fixed seat (110) is fixedly arranged on the upper shell (100), and a threaded hole (111) is arranged inside the fixed seat (110); The lower shell (200) is provided with a lower shell through groove (210), a counterbore (220) is arranged at a position corresponding to the threaded hole (111) on the lower shell (200), and the upper shell (100) and the lower shell (200) are threadedly connected through the threaded hole (111) and the counterbore (220); The heating component (400) includes a circuit board (410), a heating element (411) arranged on one side of the circuit board (410) close to the lower shell (200), and a heating plate (420) attached to the heating element (411). The shape of the heating plate (420) corresponds to the shape of the lower shell through groove (210). An avoidance hole (412) is arranged at a position corresponding to the fixed seat (110) on the circuit board (410), and the diameter of the avoidance hole (412) is larger than the diameter of the fixed seat (110); The elastic component (300) is used to cause the heating component (400) to generate a relative displacement in the vertical direction.

2. The thermal cover structure of a portable nucleic acid amplification analyzer according to claim 1, wherein: The elastic component (300) includes a positioning seat (310) arranged inside the top of the upper shell (100), a positioning seat hole (311) is arranged inside the positioning seat (310), a positioning pin (320) is inserted into the positioning seat hole (311), a spring (330) is sleeved on the positioning pin (320), a positioning hole (340) is arranged at a position corresponding to the positioning seat hole (311) on the circuit board (410), and the diameters of the positioning seat hole (311) and the positioning hole (340) are matched with the diameter of the positioning pin (320).

3. The thermal cover structure of a portable nucleic acid amplification analyzer according to claim 1, characterized in that: The elastic component (300) includes an elastic plate (350), a connecting rib (351) fixedly arranged inside the top of the upper shell (100), and the shape surrounded by the middle part of the connecting rib (351) is matched with the elastic plate (350).

4. The thermal cover structure of a portable nucleic acid amplification analyzer according to claim 2, wherein: The circumferential clearance between the positioning pin (320) and the positioning hole (340) on the circuit board (410) is 0.1 mm - 0.2 mm.

5. The hot lid structure of a portable nucleic acid amplification analyzer according to claim 3, characterized in that: The elastic plate (350) is made of silica gel foam material.

6. The thermal cover structure of a portable nucleic acid amplification analyzer according to claim 1, characterized in that: The heating plate (420) is a concentric circular convex platform structure, and the height of the convex platform is greater than the maximum displacement that the elastic component (300) can vertically move.

7. The hot lid structure of a portable nucleic acid amplification analyzer according to claim 1, characterized in that: A groove (421) is arranged on one side of the heating plate (420) close to the circuit board (410), a silica gel pad (430) is arranged inside the groove (421), the shape of the groove (421) is matched with the silica gel pad (430), and the silica gel pad (430) is in contact connection with the heating element (411) for heat conduction.

8. The thermal cover structure of a portable nucleic acid amplification analyzer according to claim 7, characterized in that: The heating element (411) is a heating resistor.

9. The thermal cover structure of a portable nucleic acid amplification analyzer according to claim 1, characterized in that: An upper shell connecting piece (120) is arranged at one side edge of the upper shell (100), a clamping groove (121) is arranged on the upper shell connecting piece (120), a lower shell connecting piece (230) is arranged at one side edge of the lower shell (200) far from the heating component (400), the shape of the lower shell connecting piece (230) is matched with the shape of the clamping groove (121), and the upper shell connecting piece (120) and the lower shell connecting piece (230) are inserted through the clamping groove (121).

10. The thermal cover structure of a portable nucleic acid amplification analyzer according to claim 9, characterized in that: The lower housing (200) further includes a lower cover groove (240) disposed at a position opposite to the lower housing connecting member (230).