Dynamic cell culture module

Abstract

The utility model relates to the technical field of cell culture, in particular to a dynamic cell culture module, which comprises a culture tank, a circular tube rotatably connected onto the culture tank, a plurality of air holes arranged on the circular tube, a plurality of connecting threaded holes arranged on the circular tube, a toothed ring fixedly connected onto the circular tube, a sliding frame slidably connected onto the culture tank, and a plurality of connecting threaded holes arranged on the sliding frame. A gear is rotationally connected to the sliding frame, the gear is meshed with the gear ring, a motor is fixedly connected to the sliding frame, an output shaft of the motor is fixedly connected with the gear, the electric push rod is fixedly connected to the culture groove, a telescopic rod of the electric push rod is fixedly connected with the sliding frame, the handheld groove is formed in the round pipe, and a rubber layer wraps the handheld groove. The effect of changing the gas introduction angle can be achieved in an automatic mode and a manual mode, and the stable culture effect of cells is maintained.

Description

Technical Field

[0001] The utility model relates to the technical field of cell culture, and more specifically to a dynamic cell culture module. Background Art

[0002] Cell culture is a technology that simulates the in-vivo environment in vitro, enabling cells to survive, grow, reproduce, and maintain their main structures and functions. During the cell culture process, by introducing gas into the cell culture environment and changing the gas flow rate, gas inlet angle, and air flow temperature, it is possible to change the cell growth environment and thereby achieve the effect of simulating the in-vivo production environment;

[0003] Among them, changing the gas inlet angle can produce various effects, such as improving gas distribution, enhancing gas utilization rate, and optimizing the cell production environment. Therefore, it is an important experimental factor. In the prior art, there are already related devices that can change the gas inlet angle, but most of them are automatically completed through mechanical transmission or mechanical equipment. When a mechanical failure occurs during cell culture, the effect of changing the gas inlet angle will be interrupted, and the stable cell culture effect cannot be maintained. Summary of the Utility Model

[0004] The utility model provides a dynamic cell culture module, and its beneficial effect is that it can achieve the effect of changing the gas inlet angle through both automatic and manual methods, and maintain the stable cell culture effect.

[0005] A dynamic cell culture module includes a culture tank, a circular tube is rotatably connected to the culture tank, multiple air holes are provided on the circular tube, multiple connecting threaded holes are provided on the circular tube, a toothed ring is fixedly connected to the circular tube, a sliding frame is slidably connected to the culture tank, a gear is rotatably connected to the sliding frame, the gear meshes with the toothed ring, and a motor is fixedly connected to the sliding frame, and the output shaft of the motor is fixedly connected to the gear.

[0006] It further includes an electric push rod fixedly connected to the culture tank, and the telescopic rod of the electric push rod is fixedly connected to the sliding frame.

[0007] It further includes a hand-held groove opened on the circular tube.

[0008] The hand-held groove is wrapped with a rubber layer.

[0009] It further includes a torsion spring fixedly connected between the circular tube and the culture tank.

[0010] It further includes a recording board fixedly connected to the culture tank. Description of the Drawings

[0011] The following further describes the present utility model in detail with reference to the drawings and specific implementation methods.

[0012] Figure 1 andFigure 2 It is a schematic structural diagram of a dynamic cell culture module;

[0013] Figure 3 It is a schematic structural diagram of a culture tank;

[0014] Figure 4 It is a schematic structural diagram of a recording board;

[0015] Figure 5 It is a schematic structural diagram of a circular tube;

[0016] Figure 6 It is a schematic structural diagram of an iron sheet. Specific implementation mode

[0017] As Figure 1-6 shown:

[0018] It includes a culture tank 101, a circular tube 301 is rotatably connected to the culture tank 101, a plurality of air holes are provided on the circular tube 301, a plurality of connecting threaded holes 302 are provided on the circular tube 301, a gear ring 303 is fixedly connected to the circular tube 301, a sliding frame 201 is slidably connected to the culture tank 101, a gear 204 is rotatably connected to the sliding frame 201, the gear 204 meshes with the gear ring 303, and a motor 203 is fixedly connected to the sliding frame 201, and the output shaft of the motor 203 is fixedly connected to the gear 204.

[0019] A hose that can pass gas into the circular tube 301 is connected to the circular tube 301 by screwing bolts into a plurality of connecting threaded holes 302. Then, the cells to be cultured are added into the culture tank 101 and the upper side of the culture tank 101 is covered. Then, gas is injected into the culture tank 101 by passing gas into the circular tube 301 to form a suitable cell culture environment. At the same time, the growth environment of the cells can be further provided by adjusting the temperature and flow rate of the injected gas, simulating the actual growth environment of the cells, and completing the cell culture effect;

[0020] During the process of injecting gas into the culture tank 101 through the circular tube 301, the output shaft of the motor 203 can be operated to rotate, and then the gear 204 reciprocally rotates on the sliding frame 201, so that the gear 204 drives the gear ring 303 to rotate, and then the circular tube 301 rotates on the culture tank 101, thereby continuously adjusting the gas injection angle, enabling the gas to contact the cells to be cultured at different injection angles, and further adjusting the gas injection process, achieving the effect of providing a suitable growth environment for the cells and simulating the actual growth environment of the cells, and improving the cell culture process;

[0021] If, during cell culture, when it is necessary to operate the circular tube 301 to rotate and the motor 203 that drives the driving gear 204 to rotate fails, resulting in the inability of the circular tube 301 to rotate and thus unable to achieve the effect of changing the gas inlet angle, the sliding carriage 201 can be operated to slide on the culture tank 101, so that the gear 204 is separated from the toothed ring 303, thereby removing the restriction of the gear 204 on the rotation process of the circular tube 301. Subsequently, the experimenter can manually operate the circular tube 301 to rotate on the culture tank 101 to change the angle of the circular tube 301, and then complete the operation of manually changing the gas inlet angle, so as to ensure that the effect of the gas contacting the cells to be cultured at different inlet angles can be stably carried out, avoid the interruption of this experimental factor during the experiment, and thus maintain the stable cell culture effect.

[0022] As Figure 3 shown:

[0023] It also includes an electric push rod 202 fixedly connected to the culture tank 101, and the telescopic rod of the electric push rod 202 is fixedly connected to the sliding carriage 201.

[0024] When it is necessary to operate the sliding carriage 201 to move away and remove the restriction of the gear 204 on the toothed ring 303, the telescopic rod of the electric push rod 202 can be operated to extend, thereby driving the sliding carriage 201 to slide, so that the gear 204 is separated from the originally meshing position with the toothed ring 303, and then the restriction effect of the gear 204 on the toothed ring 303 is removed. Subsequently, the experimenter manually rotates the circular tube 301 to maintain the normal progress of the subsequent effect of changing the gas inlet angle. After the motor 203 is repaired and maintained later and the output shaft of the motor 203 can rotate, the sliding carriage 201 can be moved back.

[0025] As Figure 5 shown:

[0026] It also includes a hand-held groove 305 opened on the circular tube 301.

[0027] The experimenter can complete the work of rotating the circular tube 301 by holding the hand-held groove 305, which brings convenience to the subsequent manual rotation operation of the circular tube 301.

[0028] As Figure 5 shown:

[0029] The hand-held groove 305 is wrapped with a rubber layer.

[0030] The rubber layer can protect the hands of the experimenter and prevent the hands of the experimenter from being injured by the hand-held groove 305 when holding the hand-held groove 305.

[0031] As Figure 5 shown:

[0032] It further includes a torsion spring 304 fixedly connected between the circular tube 301 and the culture tank 101.

[0033] The setting of the torsion spring 304 enables, after the experimenter rotates the circular tube 301 by a certain angle, the force for rotating the circular tube 301 to be removed. At this time, the circular tube 301 can be subjected to the torsional force of the torsion spring 304 and thus automatically reset, which further brings convenience to the process of manually rotating the circular tube 301.

[0034] As Figure 1 shown:

[0035] It further includes a recording board 103 fixedly connected to the culture tank 101.

[0036] The setting of the recording board 103 enables the experimenter to record the relevant information of the cells cultured in this culture tank 101 on the recording board 103, enabling subsequent experimenters to quickly master the specific situation of the cells cultured in this culture tank 101. Furthermore, when it is necessary to manually rotate the circular tube 301, it enables the operator to accurately master specific information such as the rotation interval time and the rotation angle, bringing convenience to actual use.

[0037] As Figure 6 shown:

[0038] It further includes a wiping cotton 402 connected to the culture tank 101.

[0039] After the cell culture is completed, the information recorded on the recording board 103 can be wiped by using the wiping cotton 402, thereby timely replacing the information on the recording board 103 and further bringing convenience to actual use.

[0040] As Figure 4 and Figure 6 shown:

[0041] It further includes an iron sheet 401, with a wiping cotton 402 fixedly connected to the iron sheet 401. A magnetic plate 104 is fixedly connected to the culture tank 101, and the magnetic plate 104 can adsorb and fix the iron sheet 401.

[0042] When the wiping cotton 402 is not in use, the iron sheet 401 is adsorbed on the magnetic plate 104 to adsorb and fix the iron sheet 401, enabling the iron sheet 401 to be grouped on the culture tank 101. When the wiping cotton 402 is needed, the iron sheet 401 is removed for use to complete the subsequent wiping work.

[0043] As Figure 3 shown:

[0044] The culture tank 101 is provided with a fixed threaded hole 102.

[0045] The culture tank 101 can be fixed by screwing bolts into the fixed threaded holes 102, achieving the effect of fixing the equipment.

[0046] As Figure 3 shown:

[0047] A plurality of the fixed threaded holes 102 are provided.

[0048] The provision of a plurality of fixed threaded holes 102 enables bolts to be screwed into a plurality of fixed threaded holes 102 simultaneously during fixation, improving the stability of the fixing effect.

Claims

1. A dynamic cell culture module, characterized in that, It includes a culture tank (101). A circular tube (301) is rotatably connected to the culture tank (101). The circular tube (301) is provided with a plurality of air holes, a plurality of connecting threaded holes (302), and a toothed ring (303) is fixedly connected to the circular tube (301). A sliding frame (201) is slidably connected to the culture tank (101). A gear (204) is rotatably connected to the sliding frame (201). The gear (204) meshes with the toothed ring (303). A motor (203) is fixedly connected to the sliding frame (201), and the output shaft of the motor (203) is fixedly connected to the gear (204).

2. The dynamic cell culture module according to claim 1, wherein, It further includes an electric push rod (202) fixedly connected to the culture tank (101), and the telescopic rod of the electric push rod (202) is fixedly connected to the sliding frame (201).

3. The dynamic cell culture module according to claim 2, characterized in that, It further includes a hand-held groove (305) opened on the circular tube (301).

4. The dynamic cell culture module according to claim 3, characterized in that, A rubber layer is wrapped on the hand-held groove (305).

5. The dynamic cell culture module according to claim 4, characterized in that, It further includes a torsion spring (304) fixedly connected between the circular tube (301) and the culture tank (101).

6. The dynamic cell culture module according to claim 1, wherein It further includes a recording board (103) fixedly connected to the culture tank (101).

7. The dynamic cell culture module according to claim 6, characterized in that, It further includes a wiping cotton (402) connected to the culture tank (101).

8. The dynamic cell culture module according to claim 7, characterized in that It further includes an iron sheet (401). The wiping cotton (402) is fixedly connected to the iron sheet (401). A magnetic plate (104) is fixedly connected to the culture tank (101), and the magnetic plate (104) can adsorb and fix the iron sheet (401).

9. The dynamic cell culture module according to claim 1, wherein, A fixing threaded hole (102) is opened on the culture tank (101).

10. A dynamic cell culture module according to claim 9, characterized in that: There are a plurality of the fixing threaded holes (102).

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