Centrifugal device for full-automatic chemiluminescence immunity analyzer

By designing a centrifugal device for a fully automatic chemiluminescence immunoassay device that includes rotating components, disinfection components and heating components, the problems of inconvenience in removal of reaction tubes and incomplete disinfection are solved, convenient operation and precise temperature control are achieved, and the accuracy and efficiency of experiments are improved.

CN223154613UActive Publication Date: 2025-07-25保定市第一中心医院
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202422006228.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-19
Publication Date
2025-07-25
Estimated Expiration
2034-08-19

AI Technical Summary

Technical Problem

The centrifugal device of the existing fully automatic chemiluminescence immunoassay device is inconvenient to remove the reaction tube, requires additional operation steps, and is not thoroughly disinfected, which affects the accuracy of the experimental results, and is inaccurate in temperature control, which affects the efficiency of biological reactions.

Method used

A fully automatic centrifugal device for chemiluminescence immunoassay was designed, including rotating components, disinfection components and heating components. The reaction tubes are easily removed through telescopic components, fully automatic disinfection is achieved, and the temperature is accurately controlled through heating components.

Benefits of technology

It improves the convenience of the reaction tube and the degree of automation of disinfection, reduces the risk of human error, ensures the accuracy and efficiency of experiments, and expands the application scope of the equipment.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN223154613U_ABST
    Figure CN223154613U_ABST
Patent Text Reader

Abstract

The utility model relates to the technical field of chemiluminescence immunoassay, in particular to a centrifugal device for a full-automatic chemiluminescence immunoassay analyzer, which comprises a box body, a rotating component, a disinfecting component and a heating component, a cavity is formed in the box body, a heat preservation layer is arranged on the inner wall of the box body, the heat preservation layer is matched with the binding face of the inner wall of the box body in shape and can abut against the binding face, a box cover is arranged on the top of the box body, and the mounting end of the box cover is hinged to the end face of the top of the box body. The top of the rotating assembly is fixedly connected with the inner top wall of the box body, the rotating assembly is used for placing a reaction tube, the disinfection assemblies are arranged in the box body, the two disinfection assemblies are symmetrically arranged with the rotating assembly as the axis, the mounting ends of the two disinfection assemblies are fixedly connected with the inner wall of the box body, and the heating assembly is arranged in the box body. The heating assembly is used for increasing the temperature in the box body, and a more efficient, safer and more accurate solution is provided for laboratory work.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The utility model relates to the technical field of chemiluminescence immunoassay, and more specifically, to a centrifugal device for a fully automatic chemiluminescence immunoassay analyzer. Background Technique

[0002] Luminescence immunoassay technology is an ultra-trace analysis method that combines luminescence analysis and immune reaction. It uses a chemical or bioluminescence system as an indicator to detect the specific binding between antigens and antibodies. This technology is widely used in medical diagnosis, biotechnology research, and clinical laboratories due to its high sensitivity and high specificity. In traditional fully automatic chemiluminescence immunoassay analyzers, a three-axis motion mechanism is usually used to achieve sample processing and the clamping of reaction tubes. Although this mechanism can achieve precise movement and positioning, after centrifugation, due to structural limitations, the removal of reaction tubes is often not convenient enough, requiring additional operation steps or manual intervention, which increases the complexity and time cost of operation. In addition, the existing centrifugal devices need to be manually disinfected after use to prevent cross-contamination and ensure the accuracy of experiments. This process is not only time-consuming and laborious, but may also lead to incomplete disinfection due to human factors, affecting the reliability of subsequent experimental results. There are also some biological reactions that need to be carried out under specific temperature conditions, which requires the luminescence immunoassay analyzer to have a temperature control function. However, not all existing devices can provide precise temperature control, which may affect the efficiency and accuracy of certain biological reactions. Content of the Utility Model

[0003] In view of this, in view of the deficiencies of the prior art, the utility model provides a centrifugal device for a fully automatic chemiluminescence immunoassay analyzer, aiming to solve at least one of the problems raised in the above background technique.

[0004] The utility model provides a centrifugal device for a fully automatic chemiluminescence immunoassay analyzer, including: a box body, a chamber is arranged inside the box body, a heat preservation layer is arranged on the inner wall of the box body, the shape of the joint surface between the heat preservation layer and the inner wall of the box body is matched, and they can be in abutting fit. A box cover is arranged on the top of the box body, and the installation end of the box cover is hinged to the end surface of the top of the box body;

[0005] A rotating assembly, the rotating assembly is arranged inside the box body, and the rotating assembly coincides with the axis of the box body. The top of the rotating assembly is fixedly connected to the inner top wall of the box body, and reaction tubes are placed on the rotating assembly;

[0006] A disinfection assembly, the disinfection assembly is arranged inside the box body, and two disinfection assemblies are symmetrically arranged with the rotating assembly as the axis. The installation ends of the two disinfection assemblies are respectively fixedly connected to the inner wall of the box body;

[0007] A heating component, which is arranged inside the box body and is used to increase the temperature inside the box body.

[0008] In some embodiments, the lateral cross-section of the box body is a rectangular structure.

[0009] In some embodiments, it further includes a liquid level gauge. A base is arranged at the bottom of the box body, the top of the base is fixedly connected to the bottom of the box body, the liquid level gauge is horizontally arranged on the base, and the installation end of the liquid level gauge is fixedly connected to the side wall of the base, and the liquid level gauge is parallel to the horizontal plane of the bottom of the base.

[0010] In some embodiments, the lateral cross-section of the top of the base is the same as that of the bottom of the box body.

[0011] In some embodiments, the lateral cross-section of the box cover is an annular structure.

[0012] In some embodiments, the rotating component includes:

[0013] A rotating motor, which is vertically arranged inside the box body, and the installation end at the top of the rotating motor is fixedly connected to the top wall of the box body;

[0014] A rotating shaft, which is vertically arranged, and the top end of the rotating shaft is fixedly connected to the output end at the bottom of the rotating motor, and the rotating motor can drive the rotating shaft to rotate;

[0015] A connecting component, a plurality of the connecting components are arranged in an annular array with the rotating shaft as the axis, and one ends of the plurality of connecting components are respectively fixedly connected to the side wall of the rotating shaft.

[0016] In some embodiments, the connecting component includes:

[0017] A connecting cylinder, which is vertically arranged, and the top opening of the connecting cylinder corresponds to the box cover, and the bottom of the connecting cylinder is provided with an opening;

[0018] A telescopic component, which is arranged at the bottom of the connecting cylinder.

[0019] In some embodiments, the telescopic component includes:

[0020] A first connecting cylinder, the top of the first connecting cylinder is provided with an opening, and the top opening of the first connecting cylinder matches the shape of the bottom opening of the connecting cylinder, and the top of the first connecting cylinder is fixedly connected and communicated with the bottom of the connecting cylinder;

[0021] An electric telescopic column, which is arranged at the inner bottom of the first connecting cylinder, and the electric telescopic column coincides with the axis of the first connecting cylinder;

[0022] A hemispherical trough body, the open end of the hemispherical trough body is arranged upward, and the bottom mounting end of the hemispherical trough body is fixedly connected to the telescopic end at the top of the electric telescopic column. The outer diameter of the hemispherical trough body matches the inner diameter of the first connecting cylinder. The electric telescopic column can drive the hemispherical trough body to move vertically up and down in the first connecting cylinder. The inner diameter at the top of the hemispherical trough body matches the outer diameter of the reaction tube.

[0023] In some embodiments, the disinfection component includes:

[0024] A liquid storage tank, the liquid storage tank is vertically arranged on the inner side wall of the box body, the side wall of the liquid storage tank is fixedly connected to the inner wall of the box body, and the liquid storage tank is communicated with a pressure tank;

[0025] A spray head, the spray head is arranged corresponding to the rotation component, and the connecting end of the spray head is communicated with the inside of the liquid storage tank.

[0026] In some embodiments, the heating component includes:

[0027] An electric heating wire, the electric heating wire is arranged inside the box body, and the bottom mounting end of the electric heating wire is fixedly connected to the inner bottom wall of the box body;

[0028] A temperature sensor, the bottom mounting end of the temperature sensor is fixedly connected to the inner wall of the box body;

[0029] A control panel, the mounting end of the control panel is fixedly connected to the outer side wall of the box body, and the control panel is electrically connected to the electric heating wire and the temperature sensor.

[0030] The above general description and the following detailed description are only exemplary and explanatory, and do not limit the present disclosure.

[0031] According to the following detailed description of exemplary embodiments with reference to the accompanying drawings, other features and aspects of the present disclosure will become clearer. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] In order to more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following will briefly introduce the drawings required for the description of the specific embodiments or the prior art. Obviously, the following drawings are some embodiments of the present invention. For those of ordinary skill in the art, other drawings can be obtained based on these drawings without creative efforts.

[0033] Figure 1 It is a front structural sectional view of a centrifugal device for a fully automatic chemiluminescence immunoassay analyzer provided by an embodiment of the present invention;

[0034] Figure 2Partial enlarged view of the centrifugal device for a fully automatic chemiluminescence immunoassay analyzer provided by an embodiment of the present utility model;

[0035] Figure 3 Partial enlarged view of the centrifugal device for a fully automatic chemiluminescence immunoassay analyzer provided by an embodiment of the present utility model.

[0036] Wherein: 1, box body; 2, chamber; 3, heat insulation layer; 4, box cover; 5, rotating assembly; 6, disinfection assembly; 7, heating assembly; 8, liquid level gauge; 9, base; 10, rotating motor; 11, rotating shaft; 12, connecting assembly; 13, connecting cylinder; 14, telescopic assembly; 15, first connecting cylinder; 16, electric telescopic column; 17, hemispherical groove body; 18, liquid storage tank; 19, spray head; 20, heating wire; 21, temperature sensor; 22, control panel. Specific embodiments

[0037] Next, the technical solutions in the embodiments of the present application will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present application.

[0038] In the description of the present application, it should be understood that the terms "center", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc. indicate the orientation or positional relationship based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present application.

[0039] The terms "first" and "second" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, features defined with "first" and "second" may explicitly or implicitly include one or more of such features. In the description of the present application, unless otherwise specified, the meaning of "a plurality" is two or more.

[0040] In the description of the present application, it should be noted that unless otherwise clearly specified and defined, the terms "installed", "connected", and "coupled" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present application can be understood according to specific circumstances.

[0041] As described in the background art, in a traditional fully automatic chemiluminescence immunoassay analyzer, a three-axis motion mechanism is usually adopted to achieve sample handling and the clamping of reaction tubes. Although this mechanism can achieve precise movement and positioning, after centrifugation is completed, due to structural limitations, the removal of the reaction tubes is often not convenient enough, and additional operation steps or manual intervention are required, which increases the complexity of the operation and the time cost. In addition, the existing centrifugal devices need to be manually disinfected after use to prevent cross-contamination and ensure the accuracy of the experiment. This process is not only time-consuming and laborious, but also may lead to incomplete disinfection due to human factors, affecting the reliability of subsequent experimental results. There are also some biological reactions that need to be carried out under specific temperature conditions, which requires the chemiluminescence immunoassay analyzer to have a temperature control function. However, not all existing devices can provide precise temperature control, which may affect the efficiency and accuracy of some biological reactions.

[0042] To address the above problems, a centrifuge device for a fully automatic chemiluminescence immunoassay analyzer proposed in this application is provided. By arranging a telescopic component at the bottom of the connecting cylinder for placing reaction tubes on the rotating motor, after the liquid in the reaction tubes is centrifuged, the reaction tubes can be pushed upward through the telescopic component, causing the tops of the reaction tubes to extend out of the connecting cylinder, facilitating taking and reducing operation steps and manual intervention, thereby improving work efficiency. Through the disinfection component provided corresponding to the connecting cylinder, it is possible to achieve full-automatic disinfection of the entire interior of the centrifuge device, reducing the need for manual disinfection, lowering the risk of human operation errors and cross-contamination, and ensuring the safety and accuracy of experiments. By arranging the heating component, the temperature inside the centrifuge device can be controlled to meet the specific temperature requirements of certain biological reactions, improving the efficiency and accuracy of the reactions, and at the same time expanding the application scope of the device. The improvement in automation level and the precision of temperature control make the experimental conditions more stable and controllable, thus improving experimental efficiency and data quality. Due to the increased automation level of the device, the need for human intervention during the experiment is reduced, and the risk of experimental failure or inaccurate data caused by improper operation is lowered. The temperature control function of the device enables it to adapt to the requirements of more types of biological reactions, enhancing the versatility and applicability of the device. Since the reaction tubes are easy to take out after centrifugation, and the device can automatically disinfect and adjust the temperature, the work process in the laboratory becomes more smooth and coherent, reducing the time for experimental preparation and cleaning work.

[0043] Refer to Figures 1-3 As shown in the figure, a centrifuge device for a fully automatic chemiluminescence immunoassay analyzer according to an embodiment of the present application includes:

[0044] A box body 1, a chamber 2 is arranged inside the box body 1, a heat-insulating layer 3 is arranged on the inner wall of the box body 1, the shape of the joint surface between the heat-insulating layer 3 and the inner wall of the box body 1 is matched, and they can be in abutting fit. A box cover 4 is arranged on the top of the box body 1, and the installation end of the box cover 4 is hinged to the top end face of the box body 1;

[0045] A rotating component 5, the rotating component 5 is arranged inside the box body 1, and the rotating component 5 coincides with the axis of the box body 1. The top of the rotating component 5 is fixedly connected to the inner top wall of the box body 1, and reaction tubes are placed on the rotating component 5;

[0046] A disinfection component 6, the disinfection component 6 is arranged inside the box body 1, and two disinfection components 6 are symmetrically arranged with the rotating component 5 as the axis. The installation ends of the two disinfection components 6 are respectively fixedly connected to the inner wall of the box body 1;

[0047] A heating component 7, the heating component 7 is arranged inside the box body 1, and the heating component 7 is used to increase the temperature inside the box body 1.

[0048] In some specific embodiments, the transverse cross-section of the box body 1 is a rectangular structure.

[0049] In some specific embodiments, it further includes a liquid level gauge 8. A base 9 is provided at the bottom of the box body 1. The top of the base 9 is fixedly connected to the bottom of the box body 1. The liquid level gauge 8 is horizontally arranged on the base 9, and the installation end of the liquid level gauge 8 is fixedly connected to the side wall of the base 9. The liquid level gauge 8 is parallel to the horizontal plane of the bottom of the base 9.

[0050] It should be understood that the liquid level gauge 8 is used to measure whether the entire centrifugal device is placed on a horizontal line.

[0051] In some specific embodiments, the transverse cross-section of the top of the base 9 is the same as the transverse cross-section of the bottom of the box body 1.

[0052] In some specific embodiments, the transverse cross-section of the box cover 4 is an annular structure.

[0053] It should be understood that one end of the box cover 4 is hinged to the end face of the box body 1 through two connecting columns, and the middle part surrounded by the box cover 4 and the box body are of an integral structure.

[0054] In some specific embodiments, the rotating assembly 5 includes:

[0055] A rotating motor 10, which is vertically arranged in the box body 1, and the installation end at the top of the rotating motor 10 is fixedly connected to the top wall of the box body 1;

[0056] A rotating shaft 11, which is vertically arranged, and the top end of the rotating shaft 11 is fixedly connected to the bottom output end of the rotating motor 10. The rotating motor 10 can drive the rotating shaft 11 to rotate;

[0057] A connecting assembly 12, a plurality of the connecting assemblies 12 are arranged in an annular array with the rotating shaft 11 as the axis, and one ends of the plurality of connecting assemblies 12 are respectively fixedly connected to the side wall of the rotating shaft 11.

[0058] In some specific embodiments, the connecting assembly 12 includes:

[0059] A connecting cylinder 13, which is vertically arranged, and the top opening of the connecting cylinder 13 corresponds to the box cover 4, and the bottom of the connecting cylinder 13 is provided with an opening;

[0060] A telescopic assembly 14, which is arranged at the bottom of the connecting cylinder 13.

[0061] In some specific embodiments, the telescopic assembly 14 includes:

[0062] The first connecting cylinder 15, an opening is provided at the top of the first connecting cylinder 15, and the shape of the opening at the top of the first connecting cylinder 15 matches the shape of the opening at the bottom of the connecting cylinder 13. The top of the first connecting cylinder 15 is fixedly connected and communicated with the bottom of the connecting cylinder 13;

[0063] The electric telescopic column 16, the electric telescopic column 16 is arranged at the inner bottom of the first connecting cylinder 15, and the electric telescopic column 16 coincides with the axis line of the first connecting cylinder 15;

[0064] The hemispherical groove body 17, the opening end of the hemispherical groove body 17 is arranged upward, and the bottom mounting end of the hemispherical groove body 17 is fixedly connected with the top telescopic end of the electric telescopic column 16. The outer diameter of the hemispherical groove body 17 matches the inner diameter of the first connecting cylinder 15. The electric telescopic column 16 can drive the hemispherical groove body 17 to move vertically up and down in the first connecting cylinder 15. The inner diameter of the top of the hemispherical groove body 17 matches the outer diameter of the reaction tube.

[0065] In some specific embodiments, the disinfection assembly 6 includes:

[0066] The liquid storage tank 18, the liquid storage tank 18 is vertically arranged on the inner side wall of the box body 1. The side wall of the liquid storage tank 18 is fixedly connected with the inner wall of the box body 1. The liquid storage tank 18 is communicated with the air pressure tank;

[0067] The spray head 19, the spray head 19 is arranged corresponding to the rotating assembly 14, and the connecting end of the spray head 19 is communicated with the inside of the liquid storage tank 18.

[0068] In some specific embodiments, the heating assembly 7 includes:

[0069] The electric heating wire 20, the electric heating wire 20 is arranged inside the box body 1, and the bottom mounting end of the electric heating wire 20 is fixedly connected with the inner bottom wall of the box body 1;

[0070] The temperature sensor 21, the bottom mounting end of the temperature sensor 21 is fixedly connected with the inner wall of the box body 1;

[0071] The control panel 22, the mounting end of the control panel 22 is fixedly connected with the outer side wall of the box body 1, and the control panel 22 is electrically connected between the electric heating wire 20 and the temperature sensor 21.

[0072] It should be understood that the electric telescopic column 16 is electrically connected with the control panel 22, and the control panel 22 controls the electric telescopic column 16 and the electric heating wire 20 to work.

[0073] Obviously, those skilled in the art can make various modifications and variations to the present utility model without departing from the spirit and scope of the present utility model. Thus, if these modifications and variations of the present utility model fall within the scope of the claims of the present utility model and their equivalent technologies, the present utility model also intends to include these modifications and variations.

Claims

1. A centrifugal device for a fully automatic chemiluminescence immunoassay analyzer, characterized in that Comprising: A box body, within which a chamber is provided. The inner wall of the box body is provided with a heat insulation layer, and the shape of the joint surface between the heat insulation layer and the inner wall of the box body is matched so that they can be abutted and fitted. A box cover is provided at the top of the box body, and the mounting end of the box cover is hinged to the top end face of the box body; A rotating assembly, which is arranged within the box body and coincides with the axis line of the box body. The top of the rotating assembly is fixedly connected to the inner top wall of the box body, and reaction tubes are placed on the rotating assembly; A disinfection assembly, which is arranged within the box body, and two disinfection assemblies are symmetrically arranged with the rotating assembly as the axis. The mounting ends of the two disinfection assemblies are respectively fixedly connected to the inner wall of the box body; A heating assembly, which is arranged inside the box body and is used to increase the temperature inside the box body.

2. The centrifugal device for a fully automatic chemiluminescence immunoassay analyzer according to claim 1, wherein, The transverse cross-section of the box body is a rectangular structure.

3. The centrifugal device for a fully automatic chemiluminescence immunoassay analyzer according to claim 1, wherein, It further includes a liquid level gauge. A base is provided at the bottom of the box body, and the top of the base is fixedly connected to the bottom of the box body. The liquid level gauge is horizontally arranged on the base, and the mounting end of the liquid level gauge is fixedly connected to the side wall of the base. The liquid level gauge is parallel to the horizontal plane at the bottom of the base.

4. A centrifugal device for a fully automatic chemiluminescence immunoassay analyzer according to claim 3, wherein, The transverse cross-section at the top of the base is the same as that at the bottom of the box body.

5. A centrifugal device for a fully automatic chemiluminescence immunoassay analyzer according to claim 1, characterized in that, The transverse cross-section of the box cover is an annular structure.

6. A centrifugal device for a fully automatic chemiluminescence immunoassay analyzer according to claim 1, characterized in that, The rotating assembly includes: A rotating motor, which is vertically arranged within the box body, and the mounting end at the top of the rotating motor is fixedly connected to the top wall of the box body; A rotating shaft, which is vertically arranged, and the top end of the rotating shaft is fixedly connected to the bottom output end of the rotating motor. The rotating motor can drive the rotating shaft to rotate; A connecting assembly, and a plurality of connecting assemblies are arranged in an annular array with the rotating shaft as the axis. One ends of the plurality of connecting assemblies are respectively fixedly connected to the side wall of the rotating shaft.

7. A centrifugal device for a fully automatic chemiluminescence immunoassay analyzer according to claim 6, characterized in that, The connecting assembly includes: A connecting cylinder, which is vertically arranged, and the top opening of the connecting cylinder corresponds to the box cover. An opening is provided at the bottom of the connecting cylinder; A telescopic assembly, which is arranged at the bottom of the connecting cylinder.

8. A centrifugal device for a fully automatic chemiluminescence immunoassay analyzer according to claim 7, characterized in that, The telescopic assembly includes: A first connecting cylinder, which is provided with an opening at the top, and the top opening of the first connecting cylinder is matched with the bottom opening of the connecting cylinder in shape. The top of the first connecting cylinder is fixedly connected and communicated with the bottom of the connecting cylinder; An electric telescopic column, which is arranged at the inner bottom of the first connecting cylinder and coincides with the axis line of the first connecting cylinder; A hemispherical groove body, with the opening end facing upward. The mounting end at the bottom of the hemispherical groove body is fixedly connected to the top telescopic end of the electric telescopic column. The outer diameter of the hemispherical groove body is matched with the inner diameter of the first connecting cylinder. The electric telescopic column can drive the hemispherical groove body to move vertically up and down within the first connecting cylinder. The inner diameter at the top of the hemispherical groove body is matched with the outer diameter of the reaction tube.

9. A centrifugal device for a fully automatic chemiluminescence immunoassay analyzer according to claim 1, characterized in that, The disinfection assembly includes: A liquid storage tank, which is vertically arranged on the inner side wall of the box body. The side wall of the liquid storage tank is fixedly connected to the inner wall of the box body, and the liquid storage tank is communicated with a pressure tank; A nozzle, the nozzle is arranged corresponding to the rotating assembly, and the connection end of the nozzle is in internal communication with the liquid storage tank.

10. The centrifugal device for a fully automatic chemiluminescence immunoassay analyzer according to claim 1, wherein, The heating assembly includes: A heating wire, the heating wire is arranged inside the box body, and the bottom mounting end of the heating wire is fixedly connected to the inner bottom wall of the box body; A temperature sensor, the bottom mounting end of the temperature sensor is fixedly connected to the inner wall of the box body; A control panel, the mounting end of the control panel is fixedly connected to the outer side wall of the box body, and the control panel is electrically connected to the heating wire and the temperature sensor.