Portable chromosome blowing and beating mixing machine

Through the design of the portable chromosome pipetting and mixing machine, the problems of low manual operation efficiency and unstable quality are solved, and automated mixing and high-quality chromosome suspension treatment are realized.

CN223154629UActive Publication Date: 2025-07-25TIANJIN JIANKANG HUAMEI MEDICAL DIAGNOSTIC TECH CO LTD
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Patent Information

Application Number
CN202421503856.6
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-28
Publication Date
2025-07-25
Estimated Expiration
2034-06-28

AI Technical Summary

Technical Problem

The pipetting and mixing of chromosomal suspension requires manual operation, which is inefficient and unstable in quality, which is greatly affected by the operator.

Method used

A portable chromosome pipetting and mixing machine is designed, including a handpiece, a driving mechanism, a clamping mechanism and a gas generating mechanism. The driving mechanism drives the pipetting parts to rotate, the clamping mechanism fixes the pipetting parts, and the gas generating mechanism transports gas to generate uniform bubbles, which improves the mixing efficiency and quality.

Benefits of technology

It realizes automated mixing of chromosomal suspensions, improves efficiency and quality, reduces manpower and is easy to carry.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model belongs to the technical field of chromosome culture, and discloses a portable chromosome blowing and beating mixing machine which comprises a handpiece, a driving mechanism, a clamping mechanism and a gas generating mechanism, the driving mechanism comprises a driving piece used for driving a blowing and beating piece to rotate so as to stir and mix chromosome suspension, the clamping mechanism is used for fixing the blowing and beating piece, and the gas generating mechanism is used for generating gas. The gas generating mechanism is used for conveying gas to the blowing and beating piece so as to generate uniform bubbles in the stirring process, the chromosome suspension is further blown and beaten, and the blowing and beating quality is improved.
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Description

Technical Field

[0001] The utility model relates to the technical field of chromosome culture, in particular to a portable chromosome pipetting and mixing machine. Background Art

[0002] Chromosomes are structures that appear during the mitosis of cells visible under a microscope. Therefore, it is necessary to obtain chromosome specimens and examine them under a microscope to analyze their cell ploidy. Chromosome preparation includes blood collection, inoculation and culture, and slide preparation. During the slide preparation process, it is necessary to pipette and mix the chromosome suspension.

[0003] During the chromosome culture process in a genetic laboratory, the pipetting and mixing of the chromosome suspension need to be manually operated. Each chromosome suspension needs to be manually pipetted and mixed about 40 times. The pipetting and mixing efficiency is low. In addition, the quality of the suspension also varies depending on the operator, and the pipetting and mixing quality is poor. Content of the Utility Model

[0004] The purpose of the utility model is to provide a portable chromosome pipetting and mixing machine, which reduces manual operation, improves the pipetting efficiency and pipetting quality, and is convenient for transfer and carrying.

[0005] To achieve this purpose, the utility model adopts the following technical solutions:

[0006] A portable chromosome pipetting and mixing machine, comprising:

[0007] A handheld part, one end of the handheld part is provided with an installation groove; an installation cavity is arranged inside;

[0008] A driving mechanism, the driving mechanism includes a driving part, the driving part is installed in the installation cavity and is configured to drive the pipetting part to rotate self - sufficiently;

[0009] A clamping mechanism, the clamping mechanism includes a clamping part, the clamping part is installed in the installation groove, the clamping part includes a connecting rod and a plurality of clamping rods, one end of the connecting rod passes through the bottom of the installation groove and is drivingly connected to the output end of the driving part, the plurality of clamping rods are radially rotatably connected to the other end of the connecting rod, the plurality of clamping rods are connected by an elastic member, and an arc - shaped clamping block is arranged at the end of the clamping rod away from the connecting rod. In the first state, the plurality of arc - shaped clamping blocks are in contact and cooperate with each other in sequence to form a clamping hole, and the pipetting part is clamped in the clamping hole. In the second state, the plurality of arc - shaped clamping blocks are separated;

[0010] A gas generating mechanism, the gas generating mechanism includes an air pump and a conduit, the air pump is placed in the installation cavity and communicates with the outside, one end of the conduit is communicated with the air outlet end of the air pump, and the other end of the conduit passes through the installation cavity and is communicated with one end of the pipetting part.

[0011] Preferably, the gas generating mechanism further includes a sealing joint. The two ends of the sealing joint are respectively provided with a first connection hole and a second connection hole. The interior of the sealing joint is provided with a sealing cavity. The first connection hole and the second connection hole both communicate with the sealing cavity, and the cross-sectional dimension of the sealing cavity is larger than the aperture of the first connection hole and the aperture of the second connection hole. The other end of the air duct is circumferentially fixed to the pore wall of the first connection hole. A rolling bearing is arranged in the sealing cavity, and the outer ring of the rolling bearing is circumferentially fixed to the cavity wall of the sealing cavity. A first sealing ring is inserted into the second connection hole, and the other end of the blowing member is inserted into the first sealing ring.

[0012] Preferably, the gas generating mechanism further includes a second sealing ring, and the second sealing ring is clamped between the bottom of the inner ring of the rolling bearing and the bottom wall of the sealing cavity.

[0013] Preferably, the driving mechanism further includes a coupling shaft. One end of the coupling shaft is drivingly connected to the output end of the driving member, and the other end passes through the bottom of the installation groove and is connected to the connecting rod.

[0014] Preferably, the axis of the connecting rod coincides with the axis of the coupling shaft and passes through the center of the clamping hole.

[0015] Preferably, a through hole is formed in the bottom of the installation groove, and the through hole communicates with the installation cavity. The coupling shaft and / or the connecting rod extends into the through hole.

[0016] Preferably, the elastic member is a spring, and the spring is in a stretched state.

[0017] Preferably, the handheld part is in a gun shape.

[0018] Preferably, a power connection terminal is provided on the handheld part, and the driving member and the air pump are both electrically connected to the power connection terminal.

[0019] Preferably, the clamping rod is in a laterally placed U shape.

[0020] Advantages of the present utility model:

[0021] The present utility model provides a portable chromosome pipetting and mixing machine, including a handheld part, a driving mechanism, a clamping mechanism and a gas generating mechanism. The driving mechanism includes a driving member for driving the pipetting member to rotate self - sufficiently to stir and mix the chromosome suspension. The clamping mechanism is used to fix the pipetting member, and the gas generating mechanism is used to convey gas to the pipetting member to generate uniform bubbles during the stirring process, further pipetting the chromosome suspension and improving the pipetting quality. Description of the Drawings

[0022] Figure 1It is a schematic structural diagram of a portable chromosome pipetting and mixing machine provided by an embodiment of the present utility model;

[0023] Figure 2 It is a schematic structural diagram of a clamping mechanism provided by an embodiment of the present utility model;

[0024] Figure 3 It is a cross-sectional view of a sealing joint provided by an embodiment of the present utility model.

[0025] In the figure:

[0026] 1. Handheld part; 11. Installation cavity; 12. Installation groove; 13. Through hole; 21. Driving part; 22. Connecting shaft; 3. Clamping mechanism; 311. Link; 312. Clamping rod; 313. Arc-shaped clamping block; 32. Elastic part; 41. Air pump; 42. Air duct; 43. Sealing joint; 431. First connection hole; 432. Second connection hole; 433. Sealing cavity; 434. Rolling bearing; 435. First sealing ring; 436. Second sealing ring; 5. Electric connection terminal. Detailed implementation manners

[0027] The following further describes the present utility model in detail with reference to the drawings and embodiments. It can be understood that the specific embodiments described herein are only used to explain the present utility model, rather than limiting the present utility model. Additionally, it should be noted that for the sake of description, only parts related to the present utility model are shown in the drawings rather than all structures.

[0028] In the description of the present utility model, unless otherwise clearly defined and limited, the terms "connected", "connected to", and "fixed" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or integrated; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two elements or the interaction relationship between two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific situations.

[0029] In the present utility model, unless otherwise clearly defined and limited, the first feature being "above" or "below" the second feature may include the direct contact between the first and second features, or may include the situation where the first and second features are not in direct contact but are in contact through other features between them. Moreover, the first feature being "above", "above the top of", and "on the top of" the second feature includes the first feature being directly above and obliquely above the second feature, or simply indicating that the first feature has a higher horizontal height than the second feature. The first feature being "below", "below the bottom of", and "under the bottom of" the second feature includes the first feature being directly below and obliquely below the second feature, or simply indicating that the first feature has a lower horizontal height than the second feature.

[0030] In the description of this embodiment, the terms "upper", "lower", "right", etc., are based on the directions or positions shown in the drawings, and are only for the convenience of description and simplified operation, rather than indicating or implying that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation of the present invention. In addition, the terms "first" and "second" are only used to distinguish in the description and have no special meaning.

[0031] The purpose of this embodiment is to provide a portable chromosome blowing and mixing machine, which can be used to blow and mix a small amount or a single chromosome suspension, reduce manual operation, improve blowing efficiency and blowing quality, and facilitate transfer and carrying.

[0032] See also Figures 1 - 3 A portable chromosome blowing and mixing machine provided in this embodiment includes a handheld piece 1, a driving mechanism, a clamping mechanism 3 and a gas generating mechanism, wherein the driving mechanism is used to drive the blowing piece to rotate to stir and mix the chromosome suspension, the clamping mechanism 3 is used to fix the blowing piece, and the gas generating mechanism is used to transport gas to the blowing piece to generate uniform bubbles during the stirring process, further blow the chromosome suspension, and improve the blowing quality, and the driving mechanism, the clamping mechanism 3 and the gas generating mechanism are all installed on the handheld piece 1.

[0033] In this embodiment, the hand-held component 1 is in the shape of a gun, which is convenient for holding, and the blowing component is in the shape of a straight tube.

[0034] The driving mechanism includes a driving member 21 and a connecting shaft 22. The driving member 21 is installed in the installation cavity 11 of the handpiece 1 and is used to provide driving force for the self-rotation of the blowing member. One end of the connecting shaft 22 is drivingly connected to the output end of the driving member 21 for outputting the driving force.

[0035] The clamping mechanism 3 includes a clamping member. Specifically, the clamping member is installed in a mounting groove 12 set at one end of the handpiece 1. Further, the clamping member includes a connecting rod 311 and a plurality of clamping rods 312, wherein one end of the connecting rod 311 passes through the bottom of the mounting groove 12 and is driven to be connected to the other end of the connecting shaft 22. The driving member 21 is started, and the connecting rod 311 is driven to rotate under the action of the connecting shaft 22; further, the plurality of clamping rods 312 are radially rotatably connected to the other end of the connecting rod 311, and the plurality of clamping rods 312 are connected by elastic members 32. An arc-shaped clamping block 313 is provided at one end of the clamping rod 312 away from the connecting rod 311. In the first state, the plurality of arc-shaped clamping blocks 313 are contacted and matched in sequence to form a clamping hole, and the blowing member is clamped in the clamping hole. In the second state, that is, under an external force state, the clamping rod 312 is pushed to separate the plurality of arc-shaped clamping blocks 313 to replace the blowing member.

[0036] Optionally, the clamping rod 312 is in a laterally placed U shape, and the protruding ends of the clamping rod 312 face away from each other to provide a larger space for cooperating with the clamping and blowing member.

[0037] Preferably, the elastic member 32 is a spring, and the spring is always in a stretched state. Therefore, the plurality of clamping rods 312 always have a tendency to approach each other to form a clamping hole in the first state.

[0038] Further preferably, a through hole 13 is provided at the bottom of the installation groove 12. The installation groove 12 communicates with the installation cavity 11 through the through hole 13, and the connecting rod 311 and / or the coupling shaft 22 pass through the through hole 13 to achieve connection.

[0039] In this embodiment, the axis of the connecting rod 311 coincides with the axis of the coupling shaft 22, and after the clamping hole is formed, it passes through the center of the clamping hole to ensure that the blowing member rotates around its own axis.

[0040] The gas generating mechanism includes an air pump 41 and a gas guide pipe 42. The air pump 41 is placed in the installation cavity 11. The air pump 41 includes an air inlet end and an air outlet end. Its air inlet end communicates with the outside, and the air outlet end communicates with one end of the gas guide pipe 42. The other end of the gas guide pipe 42 passes through the installation cavity 11 and communicates with one end of the blowing member to continuously input gas into the blowing member, which is beneficial to mixing the chromosome suspension evenly.

[0041] A power connection terminal 5 is provided on the handheld member 1. The driving member 21 and the air pump 41 are both electrically connected to the power connection terminal 5. By connecting the power connection terminal 5 to electricity, the driving member 21 and the air pump 41 are started.

[0042] To improve the stability of gas transmission, generate uniform bubbles in the chromosome suspension, and improve the blowing quality, a sealing structure is also provided in this embodiment. Specifically, the gas generating mechanism further includes a sealing joint 43. The two ends of the sealing joint 43 are respectively provided with a first connection hole 431 and a second connection hole 432. A sealing cavity 433 is provided inside the sealing joint 43. The first connection hole 431 and the second connection hole 432 both communicate with the sealing cavity 433, and the cross-sectional dimension of the sealing cavity 433 is larger than the aperture of the first connection hole 431 and the aperture of the second connection hole 432. The other end of the gas guide pipe 42 is circumferentially fixed to the hole wall of the first connection hole 431, and the fixing method is bonding;

[0043] Furthermore, a rolling bearing 434 is provided in the sealing cavity 433. The outer ring of the rolling bearing 434 is circumferentially fixed to the cavity wall of the sealing cavity 433, and the fixing method is bonding. A first sealing ring 435 is inserted into the second connection hole 432. The other end of the blowing member communicates with the sealing cavity 433 through the insertion into the first sealing ring 435. The gas guide pipe 42 inputs gas into the blowing member through the sealing cavity 433.

[0044] Preferably, the gas generating mechanism further includes a second sealing ring 436, which is clamped between the bottom of the inner ring of the rolling bearing 434 and the bottom wall of the sealing cavity 433 to further enhance the sealing effect of the sealing cavity 433.

[0045] With the above arrangement, on the one hand, the air duct 42 is hermetically connected to the blowing member through the sealing joint 43. On the other hand, while the blowing member rotates, the rolling bearing 434 is provided to ensure that the air duct 42 does not rotate synchronously, improving the structural stability.

[0046] A portable chromosome pipetting and mixing machine provided in this embodiment can pipette and mix the chromosome suspension through the gas generating mechanism and the driving mechanism, reducing manual operation, improving the pipetting efficiency and pipetting quality, and being convenient for transfer and carrying at the same time.

[0047] Obviously, the above embodiments of the present invention are only examples for clearly illustrating the present invention, rather than limiting the implementation manners of the present invention. For those of ordinary skill in the art, various obvious changes, re-adjustments and substitutions can be made without departing from the protection scope of the present invention. It is not necessary and impossible to enumerate all the implementation manners here. Any modifications, equivalent substitutions and improvements made within the spirit and principle of the present invention shall be included in the protection scope of the claims of the present invention.

Claims

1. A portable chromosome pipetting and mixing machine, characterized in that, Comprising: A hand-held part (1), one end of the hand-held part (1) is provided with a mounting groove (12); and an inner mounting cavity (11); A driving mechanism, the driving mechanism includes a driving member (21), the driving member (21) is installed in the mounting cavity (11), and is configured to drive the blowing member to rotate self; A clamping mechanism (3), the clamping mechanism (3) includes a clamping member, the clamping member is installed in the mounting groove (12), the clamping member includes a connecting rod (311) and a plurality of clamping rods (312), one end of the connecting rod (311) passes through the bottom of the mounting groove (12), and is drivingly connected to the output end of the driving member (21), a plurality of the clamping rods (312) are radially rotatably connected to the other end of the connecting rod (311), and a plurality of the clamping rods (312) are connected by an elastic member (32), and an arc-shaped clamping block (313) is provided at the end of the clamping rod (312) away from the connecting rod (311). In the first state, a plurality of the arc-shaped clamping blocks (313) are in contact and cooperate in sequence to form a clamping hole, and the blowing member is clamped in the clamping hole. In the second state, a plurality of the arc-shaped clamping blocks (313) are separated; A gas generating mechanism, the gas generating mechanism includes an air pump (41) and a conduit (42), the air pump (41) is placed in the mounting cavity (11) and communicates with the outside, one end of the conduit (42) communicates with the air outlet end of the air pump (41), and the other end of the conduit (42) passes through the mounting cavity (11) and communicates with one end of the blowing member.

2. The portable chromosome pipetting and mixing machine according to claim 1, wherein The gas generating mechanism further includes a sealing joint (43), both ends of the sealing joint (43) are respectively provided with a first connection hole (431) and a second connection hole (432), a sealing cavity (433) is provided inside the sealing joint (43), both the first connection hole (431) and the second connection hole (432) communicate with the sealing cavity (433), and the cross-sectional dimension of the sealing cavity (433) is larger than the aperture of the first connection hole (431) and the aperture of the second connection hole (432). The other end of the conduit (42) is circumferentially fixed to the pore wall of the first connection hole (431), a rolling bearing (434) is arranged in the sealing cavity (433), the outer ring of the rolling bearing (434) is circumferentially fixed to the cavity wall of the sealing cavity (433), a first sealing ring (435) is inserted into the second connection hole (432), and the other end of the blowing member is inserted into the first sealing ring (435).

3. A portable chromosome pipetting and mixing machine according to claim 2, characterized in that, The gas generating mechanism further includes a second sealing ring (436), and the second sealing ring (436) is clamped between the bottom of the inner ring of the rolling bearing (434) and the bottom wall of the sealing cavity (433).

4. A portable chromosome pipetting and mixing machine according to claim 1, characterized in that, The driving mechanism further includes a coupling shaft (22), one end of the coupling shaft (22) is drivingly connected to the output end of the driving member (21), and the other end passes through the bottom of the mounting groove (12) to connect the connecting rod (311).

5. A portable chromosome pipetting and mixing machine according to claim 4, characterized in that, The axis of the connecting rod (311) coincides with the axis of the coupling shaft (22) and passes through the center of the clamping hole.

6. A portable chromosome pipetting and mixing machine according to claim 4, wherein A through hole (13) is formed in the bottom of the installation groove (12), the through hole (13) communicates with the installation cavity (11), and the connecting shaft (22) and / or the connecting rod (311) extends into the through hole (13).

7. A portable chromosome pipetting and mixing machine according to any one of claims 1-6, characterized in that, The elastic member (32) is a spring, and the spring is in a stretched state.

8. A portable chromosome pipetting and mixing machine according to any one of claims 1-6, characterized in that, The hand-held member (1) is in a gun shape.

9. A portable chromosome pipetting and mixing machine according to any one of claims 1-6, characterized in that, A power connection terminal (5) is provided on the hand-held member (1), and both the driving member (21) and the air pump (41) are electrically connected to the power connection terminal (5).

10. A portable chromosome pipetting and mixing machine according to any one of claims 1-6, characterized in that, The clamping rod (312) is in a U shape placed sideways.