Ultrasonic dispersion magnetic bead washing device

Abstract

The utility model discloses an ultrasonic dispersion magnetic bead washing device, and relates to the technical field of magnetic bead cleaning. The device comprises a bottom plate, a vertical plate is fixedly connected to the top end of the bottom plate close to the center of one side, a supporting plate is fixedly connected to the side end of the vertical plate close to the center, a cleaning box is fixedly connected to the top end of the supporting plate, a filter plate is arranged at the bottom end in the cleaning box, and vertical blocks are symmetrically and fixedly connected to the top end of the filter plate close to the centers of the two sides. An L-shaped sliding plate is slidably connected to the center of the side end, away from the cleaning box, of the vertical plate, and a connecting plate is fixedly connected to the top end of the L-shaped sliding plate. According to the magnetic bead ultrasonic cleaning device, the motor is operated, and under the mutual cooperation of the first rotating shaft, the second rotating shaft, the three-fork plate, the first stirring blade and the second stirring blade, the washing effect on magnetic beads is improved, and the problems that two existing ultrasonic cleaning modes can only conduct local cleaning, and the cleaning efficiency is high are solved. And an external stirring device is also needed to complete ultrasonic cleaning.

Description

Technical Field

[0001] The utility model relates to the technical field of magnetic bead cleaning, in particular to an ultrasonic dispersion magnetic bead washing device. Background Art

[0002] In the biomedical field, nanomagnetic materials have the advantages of large specific surface area, rapid and efficient, easy separation and automation, and are therefore suitable for nucleic acid extraction, protein separation, cell sorting, probe capture, medical imaging contrast agents and chemiluminescence detection. Nanomagnetic materials such as magnetic composite microspheres and magnetic microspheres are compounded with non-magnetic materials such as organic polymers, biomacromolecules, and inorganic substances in a certain structure or after group modification, different magnetic composite products can be obtained. These magnetic composite products are collectively referred to as "magnetic beads";

[0003] Currently, magnetic bead ultrasonic cleaning methods are either performed by dispersing the magnetic beads in a large beaker and placing the beaker in an ultrasonic cleaning instrument, or by using probe ultrasonic cleaning. However, both ultrasonic methods can only perform local ultrasonic cleaning and require the addition of an external stirring device to achieve uniform ultrasonic cleaning. Furthermore, after cleaning, the magnetic beads are not easily accessible, which affects processing efficiency. To address these issues, the inventors have proposed an ultrasonic dispersion magnetic bead cleaning device to address these issues. Utility Model Content

[0004] In order to solve the problems that the two existing ultrasonic cleaning methods can only perform local cleaning, and require an external stirring device to complete ultrasonic cleaning, and are not convenient to take out after the magnetic beads are cleaned and affect the processing efficiency; the purpose of the utility model is to provide an ultrasonic dispersion magnetic bead washing device.

[0005] In order to solve the above technical problems, the utility model adopts the following technical solutions: an ultrasonic dispersion magnetic bead washing device, comprising a bottom plate, a vertical plate fixedly connected to the top of the bottom plate near the center of one side, a support plate fixedly connected to the side end of the vertical plate near the center, a cleaning box fixedly connected to the top of the support plate, a filter plate provided at the bottom end of the cleaning box, vertical blocks symmetrically fixedly connected to the top of the filter plate near the center of both sides, an L-shaped slide slidably connected to the center of one side end of the vertical plate away from the cleaning box, and a connecting plate fixedly connected to the top of the L-shaped slide. The bottom end of the connecting plate is fixedly connected to a mounting box near one side, and a square plate is symmetrically fixedly connected to the bottom end of the connecting plate and near the mounting box. A top plate is fixedly connected between the bottom ends of the two square plates, and the top ends of the two vertical blocks are fixedly connected to the top plate. A rotating shaft 1 is rotatably connected to the center of the bottom end of the top plate, and a plurality of stirring blades 1 are fixedly connected to the outer ring of the rotating shaft 1. A three-pronged plate is fixedly connected to the center of the outer ring of the rotating shaft 1, and three rotating shafts 2 are fixedly connected to the inside of the three-pronged plate away from the rotating shaft, and a plurality of stirring blades 2 are fixedly connected to the outer ring of the rotating shaft 2.

[0006] Preferably, a motor is provided inside the installation box, an output end of the motor passes through the installation box and is fixedly connected to a rotating shaft, and a protective cover is symmetrically fixedly connected to the top of the filter plate near the vertical block.

[0007] Preferably, the bottom end of the top plate and near both sides are symmetrically fixedly connected with plug shafts, and the top end of the cleaning box and near both sides are symmetrically provided with slots, and the slots are adapted to the plug shafts.

[0008] Preferably, a water inlet is fixedly connected to the top of the top plate near the center, and a water outlet is fixedly connected to the bottom of the cleaning box near the center.

[0009] Preferably, an electric cylinder is fixedly connected to the top of the bottom plate near the vertical plate, the output end of the electric cylinder is fixedly connected to the L-shaped slide, and a controller is fixedly connected to the top of the bottom plate near the corner.

[0010] Compared with the prior art, the beneficial effects of the present invention are:

[0011] 1. The utility model improves the washing effect of the magnetic beads by running the motor and then cooperating between the rotating shaft 1 and the rotating shaft 2, the three-pronged plate, the stirring blade 1 and the stirring blade 2, thereby solving the problem that the two existing ultrasonic cleaning methods can only perform local cleaning and require the use of an external stirring device to complete ultrasonic cleaning;

[0012] 2. In the utility model, the electric cylinder is operated, and then the protective cover and the filter plate and the L-shaped slide plate, the connecting plate and the top plate cooperate with each other to achieve the effect of conveniently taking out the magnetic beads, thereby solving the problem of inconvenience in cleaning the magnetic beads and affecting the processing efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the following briefly introduces the drawings required for use in the embodiments or the description of the prior art. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying any creative work.

[0014] Figure 1 It is a schematic diagram of the overall structure of the utility model.

[0015] Figure 2 This is a schematic diagram of the top plate structure of the utility model.

[0016] Figure 3 This is a schematic cross-sectional view of the cleaning box of the present invention.

[0017] Figure 4 For this utility model Figure 2 Enlarged structural diagram at point A in the middle.

[0018] In the figure: 1. Bottom plate; 11. Controller; 12. Support plate; 13. Electric cylinder; 2. Vertical plate; 21. L-shaped slide; 22. Connecting plate; 23. Top plate; 24. Mounting box; 25. Insert shaft; 26. Motor; 27. Rotating shaft 1; 28. Three-pronged plate; 29. Rotating shaft 2; 3. Cleaning box; 31. Filter plate; 32. Vertical block; 33. Protective cover; 34. Slot. DETAILED DESCRIPTION

[0019] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0020] Example: Figure 1-4 As shown, the utility model provides a technical solution: an ultrasonic dispersion magnetic bead washing device, comprising a bottom plate 1, a vertical plate 2 is fixedly connected to the top of the bottom plate 1 near the center of one side, a support plate 12 is fixedly connected to the side end of the vertical plate 2 near the center, a cleaning box 3 is fixedly connected to the top of the support plate 12, a filter plate 31 is provided at the bottom end of the cleaning box 3, a vertical block 32 is symmetrically fixedly connected to the top of the filter plate 31 near the center of both sides, an L-shaped slide 21 is slidably connected to the center of one side end of the vertical plate 2 away from the cleaning box 3, a connecting plate 22 is fixedly connected to the top of the L-shaped slide 21, and a connecting plate 22 is fixedly connected to the bottom end of the connecting plate 22. A mounting box 24 is fixedly connected near one side, a square plate is symmetrically fixedly connected to the bottom end of the connecting plate 22 and near the mounting box 24, a top plate 23 is fixedly connected between the bottom ends of the two square plates, and the top ends of the two vertical blocks 32 are fixedly connected to the top plate 23, a rotating shaft 27 is rotatably connected to the center of the bottom end of the top plate 23, a plurality of stirring blades 1 are fixedly connected to the outer ring of the rotating shaft 1 27, a three-pronged plate 28 is fixedly connected to the center of the outer ring of the rotating shaft 1 27, three rotating shafts 29 are fixedly connected to the inside of the three-pronged plate 28 away from the rotating shaft 1 27, and a plurality of stirring blades 2 are fixedly connected to the outer ring of the rotating shaft 2 29.

[0021] A motor 26 is provided inside the installation box 24 , and an output end of the motor 26 passes through the installation box 24 and is fixedly connected to a rotating shaft 1 27 .

[0022] By adopting the above technical solution, the motor 26 is operated, thereby causing the fixedly connected rotating shaft 1 27 to rotate.

[0023] A protective cover 33 is symmetrically fixedly connected to the top of the filter plate 31 and close to the vertical block 32.

[0024] By adopting the above technical solution, two protective covers 33 are provided on the top of the filter plate 31 to prevent the magnetic beads from rolling off the filter plate 31 .

[0025] Insert shafts 25 are symmetrically fixedly connected to the bottom end of the top plate 23 and near both sides.

[0026] By adopting the above technical solution, the insertion shaft 25 is provided at the bottom end of the top plate 23 to cooperate with the slot 34 to achieve the effect of placing the top plate 23 above the cleaning box 3.

[0027] Slots 34 are symmetrically provided at the top and near both sides of the cleaning box 3 , and the slots 34 are adapted to fit the insertion shaft 25 .

[0028] By adopting the above technical solution, a slot 34 is provided at the top of the cleaning box 3 in order to cooperate with the insertion shaft 25 to achieve the effect of placing the top plate 23 above the cleaning box 3.

[0029] A water inlet is fixedly connected to the top of the top plate 23 near the center, and a water outlet is fixedly connected to the bottom of the cleaning box 3 near the center.

[0030] By adopting the above technical solution, a water inlet is provided at the top of the top plate 23 in order to add clean water into the cleaning box 3 .

[0031] An electric cylinder 13 is fixedly connected to the top of the bottom plate 1 and close to the vertical plate 2 , and an output end of the electric cylinder 13 is fixedly connected to the L-shaped slide plate 21 .

[0032] By adopting the above technical solution, the electric cylinder 13 is operated, so that the fixedly connected L-shaped slide plate 21 is moved up and down under the action of the vertical plate 2 .

[0033] A controller 11 is fixedly connected to the top of the base plate 1 near the corner.

[0034] By adopting the above technical solution, a controller 11 is provided on the top of the base plate 1 in order to facilitate the control of the device to operate.

[0035] Working principle: When using this device, the magnetic beads can be placed inside the cleaning box 3 first, and then clean water can be added to the cleaning box 3 through the water inlet. Subsequently, the motor 26 can be operated to make the fixedly connected rotating shaft 1 27 drive the stirring blade 1 to rotate. Then, under the action of the three-pronged plate 28, the three rotating shafts 29 can drive the stirring blade 2 to rotate, thereby achieving the effect of mixing and stirring the inside of the cleaning box 3, thereby improving the washing effect of the magnetic beads, thereby solving the problem that the two existing ultrasonic cleaning methods can only perform local cleaning and require the use of an external stirring device to complete ultrasonic cleaning;

[0036] When the magnetic beads are cleaned, the sewage inside the cleaning box 3 can be discharged outward through the water outlet. The protective cover 33 prevents the magnetic beads from rolling outward with the sewage. The sewage will flow out through the filter holes, and the magnetic beads will gather above the filter plate 31. Then, by running the electric cylinder 13, the fixedly connected L-shaped slide plate 21 will rise, and with the cooperation of the connecting plate 22, the top plate 23 and the vertical block 32 will drive the filter plate 31 to rise. After the filter plate 31 is moved out of the cleaning box 3, the operation of the electric cylinder 13 can be stopped, thereby achieving the effect of conveniently taking out the magnetic beads, thereby solving the problem of inconvenient taking out and affecting the processing efficiency after the magnetic beads are cleaned.

[0037] Obviously, those skilled in the art may make various modifications and variations to the present invention without departing from the spirit and scope of the present invention. Thus, if such modifications and variations fall within the scope of the claims of the present invention and their equivalents, the present invention is intended to include such modifications and variations.

Claims

1. An ultrasonic dispersion magnetic bead washing device, comprising a bottom plate (1), characterized in that: The top of the bottom plate (1) is fixedly connected to a vertical plate (2) near the center of one side, the side end of the vertical plate (2) is fixedly connected to a support plate (12) near the center, the top of the support plate (12) is fixedly connected to a cleaning box (3), the bottom end of the cleaning box (3) is provided with a filter plate (31), the top of the filter plate (31) is symmetrically fixedly connected to vertical blocks (32) near the centers of both sides, the center of the side end of the vertical plate (2) away from the cleaning box (3) is slidably connected to an L-shaped slide plate (21), the top of the L-shaped slide plate (21) is fixedly connected to a connecting plate (22), and the bottom of the connecting plate (22) is fixedly connected to a mounting box (24) near one side. The bottom end of the connecting plate (22) is symmetrically fixedly connected with a square plate near the installation box (24), the bottom ends of the two square plates are fixedly connected with a top plate (23), and the top ends of the two vertical blocks (32) are fixedly connected to the top plate (23), the center of the bottom end of the top plate (23) is rotatably connected with a rotating shaft (27), the outer ring of the rotating shaft (27) is fixedly connected with a plurality of stirring blades (1), the center of the outer ring of the rotating shaft (27) is fixedly connected with a three-pronged plate (28), the inside of the three-pronged plate (28) is fixedly connected with three rotating shafts (29) away from the rotating shaft (27), and the outer ring of the rotating shaft (29) is fixedly connected with a plurality of stirring blades (2).

2. The ultrasonic dispersion magnetic bead washing device according to claim 1, wherein: A motor (26) is provided inside the installation box (24), and an output end of the motor (26) passes through the installation box (24) and is fixedly connected to a rotating shaft (27).

3. The ultrasonic dispersion magnetic bead washing device according to claim 1, wherein: A protective cover (33) is symmetrically fixedly connected to the top of the filter plate (31) and close to the vertical block (32).

4. The ultrasonic dispersion magnetic bead washing device according to claim 1, wherein: Insert shafts (25) are symmetrically fixedly connected to the bottom end of the top plate (23) and near both sides.

5. The ultrasonic dispersion magnetic bead washing device according to claim 4, characterized in that: Slots (34) are symmetrically provided at the top of the cleaning box (3) and near both sides, and the slots (34) are adapted to the insertion shaft (25).

6. The ultrasonic dispersion magnetic bead washing device according to claim 1, characterized in that: The top end of the top plate (23) is fixedly connected to a water inlet near the center, and the bottom end of the cleaning box (3) is fixedly connected to a water outlet near the center.

7. The ultrasonic dispersion magnetic bead washing device according to claim 1, characterized in that: An electric cylinder (13) is fixedly connected to the top of the bottom plate (1) and close to the vertical plate (2), and the output end of the electric cylinder (13) is fixedly connected to the L-shaped slide plate (21).

8. The ultrasonic dispersion magnetic bead washing device according to claim 1, characterized in that: A controller (11) is fixedly connected to the top of the bottom plate (1) near the corner.

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