Consumable material for preparing cell suspension liquid

Abstract

The utility model provides a cell suspension preparation consumable which comprises a shell, a filter plate is arranged in the shell, and the interior of the shell is divided into an upper cavity and a lower cavity by the filter plate; an upper cover is arranged at the top of the shell, a rotating shaft is arranged on the upper cover, the lower end of the rotating shaft penetrates through the upper cover and is provided with an abrasive disc, and the abrasive disc is in contact with the filter plate; one side of the shell is also provided with an extraction channel, and the lower end of the extraction channel is communicated with the lower cavity. According to the utility model, the interior of the shell is divided into the upper cavity and the lower cavity by the filter plate, and dispersed cell suspension liquid is stored in the lower cavity, so that cells are prevented from being broken due to repeated grinding; the extraction channel can be used for subsequently extracting the cell suspension through the needle tube, so that isolated preparation, extraction and transfer of the cell suspension are realized, the cell suspension is prevented from being in contact with the external environment in the transfer process, and the pollution risk is reduced.

Description

Technical Field

[0001] The utility model relates to the technical field of hair growth liquid preparation devices, in particular to a consumable material for preparing a cell suspension. Background Art

[0002] Currently, the clinical methods for treating seborrheic alopecia include hair transplant surgery, drug therapy, and autologous tissue microtransplantation. Among them, hair transplant surgery involves transplanting individual hair follicles and hair follicle units of the body. However, hair follicle resources are non-renewable and limited in number, making it impossible to treat large areas of hair loss. Moreover, due to technical reasons, the survival rate of hair follicles is low, and it is often necessary to damage more hair follicles to treat smaller areas of hair loss, which causes greater damage to the patient's scalp. Drug therapy will inevitably bring various side effects, and the drug dependence is strong, and rebound will occur after discontinuation. Autologous tissue microtransplantation therapy is to isolate, prepare, culture and expand healthy hair follicle tissue, purify progenitor cells, exosomes, and extracellular matrix, prepare a cell suspension, and finally inject it into the patient's hair loss area, thereby activating hair follicle cells and promoting hair growth.

[0003] However, during the process of isolating, preparing, culturing and amplifying the extracted hair follicles, it is inevitable that the cell suspension will be transferred midway. During the transfer, the cell suspension is exposed to the outside, posing a risk of contamination. Utility Model Content

[0004] The technical problem to be solved by the utility model is: how to avoid contamination of cell suspension.

[0005] The technical solution of the utility model to solve the above technical problems is as follows:

[0006] The utility model provides a consumable material for preparing a cell suspension, comprising a shell, a filter plate being provided in the shell, the filter plate dividing the interior of the shell into an upper cavity and a lower cavity; an upper cover being provided on the top of the shell, a rotating shaft being provided on the upper cover, the lower end of the rotating shaft passing through the upper cover and provided with a grinding plate, the grinding plate being in contact with the filter plate; an extraction channel being further provided on one side of the shell, the lower end of the extraction channel being communicated with the lower cavity.

[0007] The beneficial effects of the utility model are:

[0008] By adopting the utility model, the filter plate divides the interior of the shell into an upper cavity and a lower cavity. The dispersed cell suspension is stored in the lower cavity, which avoids the cells from being repeatedly ground and broken, and effectively protects the progenitor cells; the extraction channel can be used to subsequently extract the cell suspension through a needle, realizing the isolation preparation and extraction transfer of the cell suspension, avoiding contact with the external environment during the transfer process, and reducing the risk of contamination.

[0009] On the basis of the above technical solution, the present invention can also be improved as follows.

[0010] Furthermore, a plurality of elastic protrusions are provided on the upper side of the filter plate, a filter port is provided on one side of the elastic protrusion, and the filter port is connected to the lower cavity.

[0011] It is convenient to protect cells. At the same time, when the grinding disc rubs on the elastic protrusion, the elastic protrusion generates vibration, which helps to disperse the cells. The dispersed cells flow into the lower cavity from the filter port, thereby improving the extraction efficiency.

[0012] Furthermore, the filter openings are all located on one side of the elastic protrusion in the clockwise direction or the counterclockwise direction.

[0013] When the grinding disc rotates, it first contacts the side of the elastic protrusion without the filter port, thus preventing the undispersed tissue from being pushed into the filter port and ensuring the cleanliness of the cell suspension.

[0014] Furthermore, an annular step is provided on the inner side wall of the shell, and the lower end of the annular step contacts the upper edge of the filter plate.

[0015] It is convenient to improve the sealing of the edge of the filter plate, prevent the tissue from falling through the gap at the edge of the filter plate, and ensure the cleanliness of the cell suspension.

[0016] Furthermore, a central tube is provided in the shell, the inner side wall of the shell is connected to the outer side wall of the central tube via a boss, and the rotating shaft is located in the central tube.

[0017] The grinding disc is always located in the housing after leaving the factory. During assembly and use, you only need to put the upper cover on the rotating shaft and contact it with the central tube. This prevents the grinding disc from being contaminated during assembly and use, ensuring the cleanliness of the cell suspension; at the same time, it prevents a small amount of splashing droplets from leaking from the gap between the rotating shaft and the upper cover.

[0018] Furthermore, a lower boss is provided at the lower end of the upper cover, the lower boss extends into the shell, and the upper end of the central tube extends into the lower boss; a sleeve is also provided in the middle of the upper cover, and the sleeve is sleeved on the rotating shaft.

[0019] When the upper cover is closed on the shell, the gap from the top of the central tube to the middle of the upper cover forms a curved shape, which effectively prevents liquid from leaking and facilitates environmental protection and cleanliness.

[0020] Furthermore, an extraction tube is provided at the lower end of the extraction channel. The diameter of the extraction tube is smaller than the diameter of the extraction channel, and the lower end of the extraction tube extends to the lower part of the lower cavity.

[0021] When extracting the cell suspension, the needle can be inserted into the extraction channel and the needle passes through the extraction tube for extraction; this is convenient for reducing the area of the opening connecting the lower cavity and the outside world, and preventing external impurities from contaminating the cell suspension through the extraction channel.

[0022] Furthermore, the upper cross-section of the rotating shaft is square.

[0023] The external power equipment cooperates with the square shaft to facilitate torque transmission and easy connection.

[0024] Furthermore, a power adapter is sleeved on the upper portion of the rotating shaft, and the power adapter cooperates with the upper portion of the rotating shaft for transmission through the square inner hole.

[0025] The power adapter can be used to connect with power equipment such as rotor machines and is easy to install.

[0026] Furthermore, a mounting plate is provided at the upper end of the power adapter, a mounting hole is provided in the middle of the mounting plate, and two semi-cylindrical transmission blocks are provided at the upper end of the mounting plate. The two transmission blocks are located on both sides of the mounting hole, and the open sides of the two transmission blocks are arranged in a clockwise direction along the mounting plate.

[0027] During installation, the positioning pin of the rotor machine is inserted into the mounting hole, which is convenient for positioning and connecting with the power adapter; two shifting fingers can be extended from the lower side of the turntable of the rotor machine, and the shifting fingers enter from the opening side of the transmission block. When the rotor machine is working, the shifting fingers push the transmission block in a counterclockwise direction, thereby driving the power adapter to rotate; it is easy to install and has good transmission stability. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 It is a structural diagram of the present utility model.

[0029] Figure 2 Schematic diagram of the structure of the power adapter.

[0030] In the accompanying drawings, the technical features represented by the reference numerals are as follows:

[0031] 1-housing; 2-filter plate; 3-upper cavity; 4-lower cavity; 5-upper cover; 6-rotating shaft; 7-grinding disc; 8-extraction channel; 9-annular step; 10-elastic protrusion; 11-center tube; 12-lower boss; 13-sleeve; 14-extraction tube; 15-power adapter; 16-mounting plate; 17-mounting hole; 18-transmission block. DETAILED DESCRIPTION

[0032] The principles and features of the present invention are described below in conjunction with the accompanying drawings. The examples given are only used to explain the present invention and are not used to limit the scope of the present invention.

[0033] This utility model refers to Figure 1-2 .

[0034] The utility model provides a consumable material for preparing a cell suspension, comprising a shell 1, wherein a filter plate 2 is provided in the shell 1, and the filter plate 2 divides the interior of the shell 1 into an upper cavity 3 and a lower cavity 4; an upper cover 5 is provided on the top of the shell 1, and a rotating shaft 6 is provided on the upper cover 5, the lower end of the rotating shaft 6 passes through the upper cover 5 and is provided with a grinding plate 7, and the grinding plate 7 is in contact with the filter plate 2; an extraction channel 8 is also provided on one side of the shell 1, and the lower end of the extraction channel 8 is communicated with the lower cavity 4.

[0035] principle:

[0036] During use, healthy hair follicle tissue is placed in the upper cavity 3 of the shell 1, and a certain amount of protective liquid is added or not as needed, the upper cover 5 is covered, and the upper end of the rotating shaft 6 is connected to a power device (generally a rotor machine, but other devices such as a motor can also be used). After the power device is started, it drives the rotating shaft 6 and the grinding disc 7 to rotate, and the grinding disc 7 circulates on the filter plate 2, thereby grinding the hair follicle tissue. The dispersed progenitor cells, exosomes, and extracellular matrix enter the lower cavity 4 of the shell 1 through the filter plate 2, while impurities such as hair and dandruff remain in the upper cavity 3. After the hair follicle tissue is completely dispersed, a needle is inserted into the extraction channel 8 from top to bottom, and the needle is inserted into the bottom of the lower cavity 4, thereby extracting the cell suspension in the lower cavity 4 to complete the extraction. The cell suspension can then be injected into the patient's hair loss area to activate the hair follicle cells and promote hair growth.

[0037] By adopting the utility model, the filter plate 2 divides the interior of the shell 1 into an upper cavity 3 and a lower cavity 4. The dispersed cell suspension is stored in the lower cavity 4, which prevents the cells from being repeatedly ground and broken, and effectively protects the progenitor cells; the extraction channel 8 can be used to subsequently extract the cell suspension through a needle, thereby realizing the isolation preparation and extraction transfer of the cell suspension, avoiding contact with the external environment during the transfer process, and reducing the risk of contamination.

[0038] Furthermore, a plurality of elastic protrusions 10 are provided on the upper side of the filter plate 2 , and a filter port is provided on one side of the elastic protrusion 10 , and the filter port is connected to the lower cavity 4 .

[0039] Note: The elastic protrusion 10 can be produced by punching the filter plate 2 .

[0040] It is convenient to protect cells. At the same time, when the grinding disc 7 rubs on the elastic protrusion 10, the elastic protrusion 10 generates vibration, which helps to promote cell dispersion. The dispersed cells flow into the lower cavity 4 from the filter port, thereby improving the extraction efficiency.

[0041] Furthermore, the filter ports are all located on one side of the elastic protrusion 10 in the clockwise direction or the counterclockwise direction.

[0042] When the grinding disc 7 rotates, it first contacts the side of the elastic protrusion 10 without the filter port, thereby preventing the undispersed tissue from being pushed into the filter port and ensuring the cleanliness of the cell suspension.

[0043] Furthermore, an annular step 9 is provided on the inner side wall of the housing 1 , and the lower end of the annular step 9 contacts the upper edge of the filter plate 2 .

[0044] This facilitates improving the sealing performance of the edge of the filter plate 2, preventing tissue from falling through the gap at the edge of the filter plate 2, and ensuring the cleanliness of the cell suspension.

[0045] Furthermore, a central tube 11 is provided in the shell 1 , the inner side wall of the shell 1 is connected to the outer side wall of the central tube 11 via a boss, and the rotating shaft 6 is located in the central tube 11 .

[0046] After leaving the factory, the grinding disc 7 is always located in the shell 1. When assembling and using, it is only necessary to put the upper cover 5 on the rotating shaft 6 and contact it with the central tube 11, thereby avoiding contamination of the grinding disc 7 during assembly and use, and ensuring the cleanliness of the cell suspension; at the same time, it prevents a small amount of splashing droplets from leaking from the gap between the rotating shaft 6 and the upper cover 5.

[0047] Furthermore, a lower boss 12 is provided at the lower end of the upper cover 5 , and the lower boss 12 extends into the shell 1 , and the upper end of the central tube 11 extends into the lower boss 12 ; a sleeve 13 is also provided in the middle of the upper cover 5 , and the sleeve 13 is sleeved on the rotating shaft 6 .

[0048] When the upper cover 5 is closed on the housing 1 , the gap from the top of the central tube 11 to the middle of the upper cover 5 forms a curved shape, which effectively prevents liquid from leaking and facilitates environmental cleanliness.

[0049] Furthermore, an extraction tube 14 is provided at the lower end of the extraction channel 8 . The diameter of the extraction tube 14 is smaller than that of the extraction channel 8 , and the lower end of the extraction tube 14 extends to the lower part of the lower cavity 4 .

[0050] When extracting the cell suspension, the needle can be inserted into the extraction channel 8 and the needle tip passes through the extraction tube 14 for extraction; this is convenient for reducing the area of the opening connecting the lower cavity 4 with the outside world, and preventing external impurities from contaminating the cell suspension through the extraction channel 8.

[0051] Furthermore, the upper cross-section of the rotating shaft 6 is square.

[0052] The external power device cooperates with the square rotating shaft 6 to facilitate torque transmission and convenient connection.

[0053] Furthermore, a power adapter 15 is sleeved on the upper portion of the rotating shaft 6 , and the power adapter 15 cooperates with the upper portion of the rotating shaft 6 for transmission through a square inner hole.

[0054] The power adapter 15 can be used to connect to power equipment such as a rotor machine and is easy to install.

[0055] Furthermore, a mounting plate 16 is provided at the upper end of the power adapter 15, a mounting hole 17 is provided in the middle of the mounting plate 16, and two semi-cylindrical transmission blocks 18 are provided at the upper end of the mounting plate 16. The two transmission blocks 18 are located on both sides of the mounting hole 17, and the open sides of the two transmission blocks 18 are arranged in a clockwise direction along the mounting plate 16.

[0056] During installation, the positioning pin of the rotor machine is inserted into the mounting hole 17, which is convenient for positioning and engaging with the power adapter 15; two shifting fingers can be extended from the lower side of the turntable of the rotor machine, and the shifting fingers enter from the open side of the transmission block 18. When the rotor machine is working, the shifting fingers push the transmission block 18 in a counterclockwise direction, thereby driving the power adapter 15 to rotate; the installation is convenient and the transmission stability is good.

[0057] In the description of the present invention, it should be understood that if there are descriptive terms indicating orientation, direction or positional relationship, such as: "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., the orientation or positional relationship indicated in this specification is based on the orientation or positional relationship shown in the accompanying drawings, which is only for the convenience of understanding the present invention and simplifying the description, and does not indicate or imply that the referred part, element or whole must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0058] In addition, if there are order description terms, such as "first", "second", etc., their use in this specification is to facilitate understanding or simplify the description. For example, in order to distinguish multiple technical features with the same type or function, but they have to be mentioned separately, this specification may use prefix or suffix order description terms to distinguish them. Therefore, it cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" can explicitly or implicitly include at least one of such features. In the description of this utility model, the meaning of "multiple" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0059] In the present invention, if terms describing the relative functional relationship of structures are used, such as "install", "connect", "connect", "fix", etc., they should be understood in a broad sense unless otherwise clearly specified and limited. For example, "install", "connect", "connect", etc. can be fixed connections, detachable connections, or integrated; can be mechanical connections or electrical connections; can be direct connections or indirect connections through an intermediate medium, can be internal connections between two elements or interactive relationships between two elements; "fix" can be fixed to form an integral body, or can be detachably fixed through fasteners; can be directly fixed or fixed through an intermediate medium. For ordinary technicians in this field, the specific meanings of the above-mentioned descriptive terms in the present invention can be understood according to the specific circumstances, the context, the coherence of the preceding and following texts, etc.

[0060] In this utility model, if descriptive terms with ancillary or connecting meaning appear, for example, a first feature being "on" or "below" a second feature, these should not be interpreted as limiting unless otherwise expressly specified or limited. For example, "on" or "below" may refer to direct contact between the first and second features, or indirect contact between the first and second features through an intermediary. Those skilled in the art will understand the specific meanings of these descriptive terms in this utility model based on the specific circumstances, context, and coherence of the preceding and following texts.

[0061] Furthermore, when a first feature is “above,” “above,” or “above” a second feature, it may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. When a first feature is “below,” “below,” or “below” a second feature, it may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0062] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in a suitable manner in any one or more embodiments or examples. In addition, those skilled in the art may combine and combine the different embodiments, examples and features of different embodiments and examples described in this specification, unless there is any contradiction, and these combinations or combinations should all fall within the scope summarized by the present invention.

[0063] Although the embodiments of the present invention have been shown and described above, it is understood that the above embodiments are illustrative and cannot be understood as limitations on the present invention. A person skilled in the art can change, modify, replace and modify the above embodiments within the scope of information available through public channels and in combination with the technical inspiration given in this application document.

Claims

1. A consumable for preparing a cell suspension, characterized in that: The invention comprises a shell (1), wherein a filter plate (2) is provided in the shell (1), and the filter plate (2) divides the interior of the shell (1) into an upper cavity (3) and a lower cavity (4); an upper cover (5) is provided on the top of the shell (1), and a rotating shaft (6) is provided on the upper cover (5), and the lower end of the rotating shaft (6) passes through the upper cover (5) and is provided with a grinding plate (7), and the grinding plate (7) contacts the filter plate (2); an extraction channel (8) is also provided on one side of the shell (1), and the lower end of the extraction channel (8) is communicated with the lower cavity (4).

2. The consumable material for preparing a cell suspension according to claim 1, characterized in that: A plurality of elastic protrusions (10) are provided on the upper side of the filter plate (2), and a filter port is provided on one side of the elastic protrusion (10), and the filter port is connected to the lower cavity (4).

3. The consumable material for preparing a cell suspension according to claim 2, characterized in that: The filter ports are located on one side of the elastic protrusion (10) in the clockwise direction or the counterclockwise direction.

4. The consumable material for preparing a cell suspension according to claim 1, wherein: An annular step (9) is also provided on the inner side wall of the housing (1), and the lower end of the annular step (9) contacts the upper edge of the filter plate (2).

5. The consumable material for preparing a cell suspension according to claim 1, characterized in that: A central tube (11) is further provided in the shell (1), the inner side wall of the shell (1) is connected to the outer side wall of the central tube (11) via a boss, and the rotating shaft (6) is located in the central tube (11).

6. The consumable material for preparing a cell suspension according to claim 5, characterized in that: The lower end of the upper cover (5) is provided with a lower boss (12), which extends into the shell (1), and the upper end of the central tube (11) extends into the lower boss (12); the middle part of the upper cover (5) is also provided with a sleeve (13), which is sleeved on the rotating shaft (6).

7. The consumable material for preparing a cell suspension according to claim 1, characterized in that: An extraction tube (14) is further provided at the lower end of the extraction channel (8). The diameter of the extraction tube (14) is smaller than the diameter of the extraction channel (8), and the lower end of the extraction tube (14) extends to the lower part of the lower cavity (4).

8. The consumable material for preparing a cell suspension according to claim 1, characterized in that: The upper cross section of the rotating shaft (6) is square.

9. The consumable material for preparing a cell suspension according to claim 8, characterized in that: The upper portion of the rotating shaft (6) is also sleeved with a power adapter (15), and the power adapter (15) cooperates with the upper portion of the rotating shaft (6) for transmission through a square inner hole.

10. The consumable material for preparing a cell suspension according to claim 9, characterized in that: The upper end of the power adapter (15) is further provided with a mounting plate (16), a mounting hole (17) is provided in the middle of the mounting plate (16), and two semi-cylindrical transmission blocks (18) are provided at the upper end of the mounting plate (16). The two transmission blocks (18) are located on both sides of the mounting hole (17), and the opening sides of the two transmission blocks (18) are arranged in the clockwise direction of the mounting plate (16).

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