Microplate reader with pre-drying treatment mechanism

By setting up electric heating wire and ventilation components in the microplate reader, the reagent plate is quickly dried, which solves the problem of drying the reagent plate after cleaning and affects turnover efficiency, and improves the efficiency of the microplate reader.

CN223205488UActive Publication Date: 2025-08-08GUANGDONG OCEAN UNIVERSITY
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Patent Information

Application Number
CN202422382369.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-29
Publication Date
2025-08-08
Estimated Expiration
2034-09-29

AI Technical Summary

Technical Problem

During the use of the existing microplate reader, the reagent plate needs to be dried after cleaning, which affects the turnover efficiency of the reagent plate.

Method used

A microplate reader with a pre-drying treatment mechanism is designed. By installing an electric heating wire and a ventilation assembly in the outer shell of the microplate reader, the heating wire is used to heat and air circulation of the ventilation assembly to quickly dry the moisture on the surface of the reagent plate, and the drying efficiency of the reagent plate is improved.

Benefits of technology

The drying process of the reagent plate is accelerated, the turnover and use efficiency of the reagent plate is improved, and the waiting time for drying after cleaning is reduced.

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Abstract

The utility model particularly relates to the technical field of microplate readers, and discloses a microplate reader with a pre-drying processing mechanism, which comprises an outer shell, a notch I is arranged on the side wall of the outer shell, a door I is rotatably connected on the side wall of the outer shell close to the notch I, two notches III are symmetrically arranged on the inner side wall of the notch I, and a door II is arranged on the inner side wall of the notch III. Electric heating wires are fixedly arranged on the inner side walls of the third notches, reagent plates are arranged in the first notches, each reagent plate comprises a plate body, a plurality of reagent grooves are formed in the surface of each plate body at equal intervals, and clamping grooves are formed in the ends of the plate bodies. Through the arrangement of the outer shell, the first notch, the first door, the reagent plate, the third notch, the electric heating wire and the isolation net, the reagent plate comprises a plate body, the external size of the plate body is matched with the internal size of the first notch, the temperature in the first notch can be increased by switching on a power supply of the electric heating wire, and therefore the plate body is dried, drying of the surface of the plate body is accelerated, and the service life of the reagent plate is prolonged. Therefore, the turnover use efficiency of the plate body is improved.
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Description

Technical Field

[0001] The utility model belongs to the technical field of microplate readers, and in particular relates to a microplate reader with a pre-drying treatment mechanism. Background Art

[0002] An enzyme-linked immunosorbent assay (ELISA) reader, also known as a microplate reader, is a specialized instrument for performing enzyme-linked immunosorbent assays (ELISAs). It's essentially a phase-change photoelectric colorimeter or spectrophotometer, and its basic operating principle and main structure are essentially the same as those of a photoelectric colorimeter.

[0003] Existing microplate readers typically include a reagent plate, a light source, a photodetector, and a control panel. The reagent plate, typically made of transparent plastic, is used to hold the specimen to be tested. Light waves emitted by the light source are converted into a monochromatic beam through a filter or monochromator, entering the specimen held in a plastic microporous electrode. Part of this monochromatic light is absorbed by the specimen, while the remaining portion passes through the specimen and strikes the photodetector. The photodetector converts this optical signal, which varies in intensity depending on the specimen, into a corresponding electrical signal. After undergoing pre-amplification, logarithmic amplification, and analog-to-digital conversion, the electrical signal is fed into a microprocessor for data processing and calculation. The test results are then displayed on a display on the control panel.

[0004] Existing microplate readers need to clean the reagent plate during use to prevent residual samples on the reagent plate from affecting subsequent test results. After cleaning, the surface of the reagent plate is wet and needs to be dried before use, which affects the turnover efficiency of the reagent plate. Utility Model Content

[0005] The utility model provides an enzyme labeling instrument with a pre-drying treatment mechanism, which aims to solve the problem that the existing enzyme labeling instrument needs to clean the reagent plate during use to avoid residual samples on the reagent plate affecting subsequent test results. The surface of the reagent plate is wet after cleaning and needs to be dried before use, thereby affecting the turnover efficiency of the reagent plate.

[0006] The utility model is achieved as follows: a microplate reader with a pre-drying treatment mechanism includes an outer shell, a notch one is provided on the side wall of the outer shell, a door one is rotatably connected to the side wall of the outer shell near the notch one, two notches three are symmetrically provided on the inner side wall of the notch one, heating wires are fixed on the inner side walls of the notch three, a reagent plate is provided inside the notch one, and the reagent plate includes a plate body, a plurality of reagent slots are equidistantly provided on the surface of the plate body, a card slot is provided at the end of the plate body, a door two is rotatably connected to the side wall of the outer shell near the door one, a notch two is provided on the side wall of the outer shell near the door two, a photoelectric detector is fixed on the inner bottom of the notch two, and a light source lamp is fixed on the inner top of the notch two.

[0007] Preferably, a control panel is fixedly provided on the side wall of the outer shell near the top of the control panel. The control panel is coupled with the light source lamp and the photodetector in turn through wires. The light source lamp and the photodetector are located in the same vertical direction, thereby improving the detection accuracy.

[0008] Preferably, a ventilation assembly is provided at the top of the outer shell, and the ventilation assembly includes a mounting bracket fixed to the top of the outer shell. The mounting bracket is in a U-shape and connected to the inside of slot one. A filter is clamped on the inner side wall of the mounting bracket to facilitate steam circulation.

[0009] Preferably, a motor is fixedly provided in the middle of the mounting frame, and a fan blade is fixedly provided at the output end of the motor, thereby improving the efficiency of steam circulation.

[0010] Preferably, a mounting seat is fixed to the inner bottom of the slot one, and a plurality of grooves are evenly spaced on the surface of the mounting seat for the plate to be clamped, and the internal dimensions of the grooves are adapted to the external dimensions of the plate, thereby improving the stability of the plate installation.

[0011] Preferably, an isolation net is fixedly provided on the inner side walls of the two notches three, and the isolation nets are all made of stainless steel and are in a grid shape, thereby improving the safety of the heating wire.

[0012] Compared with the prior art, the embodiments of the present application have the following beneficial effects:

[0013] First, by providing an outer shell, slot one, door one, reagent plate, slot three, heating wire and isolation net, the reagent plate includes a plate body, the outer size of the plate body is adapted to the inner size of slot one, and the power supply of the heating wire can increase the temperature inside slot one, thereby drying the plate body, thereby accelerating the drying of the plate surface, and thus improving the turnover efficiency of the plate body; secondly, by providing a ventilation component including a mounting frame, a filter screen, a motor and fan blades, starting the motor can drive the fan blades to rotate, thereby accelerating the air circulation inside slot one, thereby improving the drying efficiency of the plate body. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 It is a front view three-dimensional structural schematic diagram of the utility model.

[0015] Figure 2 This is a schematic diagram of the front view installation structure of the present invention.

[0016] Figure 3 It is a schematic diagram of the front cross-sectional structure of the present utility model.

[0017] Figure 4 This is a schematic structural diagram of the reagent plate of the present utility model.

[0018] The figures are marked as follows: 1. outer shell; 2. slot one; 3. door one; 4. reagent plate; 401. plate; 402. reagent tank; 403. card slot; 5. mounting base; 6. door two; 7. control panel; 8. ventilation assembly; 801. mounting bracket; 802. filter; 803. motor; 804. fan blade; 9. slot two; 10. light source lamp; 11. photoelectric detector; 12. slot three; 13. heating wire; 14. isolation net; 15. groove. DETAILED DESCRIPTION

[0019] Unless otherwise defined, all technical and scientific terms used herein have the same meanings as commonly understood by those skilled in the art to which this application belongs. The terms used in the specification of the application are only for the purpose of describing specific embodiments and are not intended to limit this application. The terms "including" and "having" and any variations thereof in the specification and claims of this application and the above-mentioned drawings are intended to cover non-exclusive inclusions. The terms "first", "second", etc. in the specification and claims of this application or the above-mentioned drawings are used to distinguish different objects, not to describe a specific order.

[0020] References to "embodiments" herein mean that a particular feature, structure, or characteristic described in connection with the embodiments may be included in at least one embodiment of the present application. The appearance of this phrase in various places in the specification does not necessarily refer to the same embodiment, nor does it constitute an independent or alternative embodiment that is mutually exclusive of other embodiments. It is understood, both explicitly and implicitly, by those skilled in the art that the embodiments described herein may be combined with other embodiments.

[0021] See also Figure 1-4The embodiment provided by the utility model is: a microplate reader with a pre-drying treatment mechanism, comprising an outer shell 1, a notch 2 is provided on the side wall of the outer shell 1, a reagent plate 4 is provided inside the notch 2, and the reagent plate 4 includes a plate body 401, the outer size of the plate body 401 is adapted to the inner size of the notch 2, the plate body 401 is made of transparent plastic material for easy light transmission, a plurality of reagent slots 402 are provided at equal intervals on the surface of the plate body 401 for filling reagent specimens, and a card slot 403 is provided at the end of the plate body 401 for the operator to manually Finger snap connection, so it is convenient to grab the plate 401, the side wall of the outer shell 1 near the slot 2 is connected to a door 3 through a hinge to close the slot 2, and two slots 3 12 are symmetrically opened on the inner wall of the slot 2. The inner wall of the slot 3 12 is fixed with an electric heating wire 13 for heating, and the inner wall of the two slots 3 12 is fixed with an isolation net 14. The isolation net 14 is made of stainless steel and is in a grid shape. The isolation net 14 is used to isolate the heating wire 13, which improves the safety of the use of the heating wire 13. The side wall is rotatably connected to the door 26, and the side wall of the outer shell 1 near the door 26 is provided with a slot 29. The inner bottom of the slot 29 is fixed with a photodetector 11 for receiving the light source and converting it into an electrical signal for analysis. The inner top of the slot 29 is fixed with a light source lamp 10 for emitting a light source. The side wall of the outer shell 1 near the top of the control panel 7 is fixed with a control panel 7. The control panel 7 is coupled with the light source lamp 10 and the photodetector 11 through wires in turn. The light source lamp 10 and the photodetector 11 are located in the same vertical direction. The plate body containing the reagent is fixed. 401 is snapped into the inside of the slot 2 9, which improves the detection accuracy and can realize the detection and analysis of the reagent. When the inside of the reagent tank 402 adheres to water after the plate body 401 is cleaned, the operator can open the door 3 to leak out the slot 2, so that the operator can snap the plate body 401 into the inside of the groove 15, turn on the power of the heating wire 13 to generate heat, increase the temperature inside the slot 2, thereby accelerating the evaporation of water inside the reagent tank 402, thereby improving the drying efficiency of the reagent plate 401, and thus improving the turnover efficiency of the reagent plate 4.

[0022] A ventilation assembly 8 is provided at the top of the outer shell 1. The ventilation assembly 8 includes a mounting bracket 801 fixed to the top of the outer shell 1 by bolts. The mounting bracket 801 is in a U-shape and is connected to the inside of the slot 2 to facilitate steam circulation. A filter 802 is clamped on the inner wall of the mounting bracket 801. The filter 802 is in a grid shape and is used to filter dust to avoid internal pollution of the slot 2. A motor 803 is fixed in the middle of the mounting bracket 801, and a fan blade 804 is fixed at the output end of the motor 803. Starting the motor 803 can drive the fan blade 804 to rotate, thereby improving the efficiency of steam circulation and further accelerating drying.

[0023] A mounting seat 5 is fixed to the inner bottom of the slot 2, and a plurality of grooves 15 are evenly spaced on the surface of the mounting seat 5 for the plate 401 to engage. The internal dimensions of the grooves 15 are adapted to the external dimensions of the plate 401, thereby improving the stability of the installation of the plate 401.

[0024] Working principle: When using this microplate reader with a pre-drying treatment mechanism, the operator first connects the external power supply, and drips the reagent specimens into the interior of the reagent tank 402 in sequence through the dropper. The operator then snaps the plate 401 into the interior of the slot 2 9, so that the reagent tank 402 is facing the light source lamp 10 and closes the door 2 6, thereby achieving the closure of the door 2 6. The operator presses the button on the surface of the control panel 7 to control the opening and closing of the light source lamp 10. The light source lamp 10 emits light to illuminate the surface of several specimens. The specimens absorb part of the light, and the other part of the light passes through the plate 401 and is photodetected. The detector 11 absorbs and performs light source analysis and detection, and the detection results are displayed on the display on the surface of the control panel 7, thereby realizing the detection of enzyme biological content. When the inside of the reagent tank 402 adheres to water after the reagent plate 4 is cleaned, the operator can open the door 3 to leak out the slot 2, so that the operator can easily clip the plate body 401 into the inside of the groove 15, turn on the power of the heating wire 13 to generate heat, thereby increasing the temperature inside the slot 2, thereby accelerating the evaporation of water inside the reagent tank 402, thereby improving the drying efficiency of the reagent plate 4, and thus improving the turnover efficiency of the reagent plate 4.

[0025] Secondly, by providing the ventilation assembly 8, the starting motor 803 can drive the fan blades 804 to rotate, thereby accelerating the air circulation inside the slot 1 2, thereby further improving the efficiency of drying the reagent plate 4.

[0026] It should be noted that for the aforementioned embodiments, for simplicity of description, they are all expressed as a series of action combinations. However, those skilled in the art should be aware that the present invention is not limited by the order of the actions described, because according to the present invention, certain steps may be performed in other orders or simultaneously. Secondly, those skilled in the art should also be aware that the embodiments described in this specification are all preferred embodiments, and the actions and modules involved are not necessarily required by the present invention.

[0027] In the several embodiments provided in this application, it should be understood that the disclosed devices can be implemented in other ways. For example, the device embodiments described above are merely illustrative, such as the division of the above-mentioned units. In actual implementation, there may be other division methods, such as multiple units or components can be combined or integrated into another system, or some features can be ignored or not executed. Another point is that the coupling or communication connection between each other shown or discussed can be through some interfaces, and the indirect coupling or communication connection between devices or units can be in the form of telecommunications or other forms.

[0028] The units described above as separate components may or may not be physically separate, and the components shown as units may or may not be physical units, that is, they may be located in one place or distributed across multiple network units. Some or all of these units may be selected according to actual needs to achieve the purpose of the solution of this embodiment.

[0029] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit the scope of protection of the present invention. Obviously, the embodiments described are only some embodiments of the present invention, rather than all embodiments. Based on these embodiments, all other embodiments obtained by ordinary technicians in this field without making any creative work are within the scope to be protected by the present invention. Although the present invention has been described in detail with reference to the above embodiments, ordinary technicians in this field can still combine, add, delete or make other adjustments to the features in the various embodiments of the present invention according to the circumstances without conflict, without making any creative work, so as to obtain different other technical solutions that do not deviate from the concept of the present invention in essence, and these technical solutions also fall within the scope to be protected by the present invention.

Claims

1. A microplate reader with a pre-drying treatment mechanism, characterized in that: The invention comprises an outer shell (1): a notch (2) is provided on the side wall of the outer shell (1); a door (3) is rotatably connected to the side wall of the outer shell (1) near the notch (2); two notches (12) are symmetrically provided on the inner side wall of the notch (2); a heating wire (13) is fixed on the inner side wall of each notch (12); a reagent plate (4) is provided inside the notch (2); the reagent plate (4) includes a plate body (401); The surface of the plate body (401) is provided with a plurality of reagent troughs (402) at equal intervals, the end of the plate body (401) is provided with a card slot (403), the side wall of the outer shell (1) close to the door one (3) is rotatably connected to the door two (6), the side wall of the outer shell (1) close to the door two (6) is provided with a slot two (9), the inner bottom of the slot two (9) is fixedly provided with a photoelectric detector (11), and the inner top of the slot two (9) is fixedly provided with a light source lamp (10).

2. The microplate reader with a pre-drying treatment mechanism according to claim 1, characterized in that: The control panel (7) is fixedly provided on a side wall of the outer shell (1) close to the upper side of the control panel (7). The control panel (7) is sequentially coupled to the light source lamp (10) and the photodetector (11) via electric wires. The light source lamp (10) and the photodetector (11) are located in the same vertical direction.

3. The microplate reader with a pre-drying treatment mechanism according to claim 2, characterized in that: A ventilation assembly (8) is provided at the top of the outer shell (1), and each of the ventilation assemblies (8) includes a mounting frame (801) fixed to the top of the outer shell (1), and each of the mounting frames (801) is in a circular shape and communicates with the interior of the slot one (2), and a filter screen (802) is clamped on the inner side wall of the mounting frame (801).

4. The microplate reader with a pre-drying treatment mechanism according to claim 3, characterized in that: A motor (803) is fixedly provided in the middle of the mounting frame (801), and a fan blade (804) is fixedly provided at the output end of the motor (803).

5. The microplate reader with a pre-drying treatment mechanism according to claim 3, characterized in that: A mounting seat (5) is fixedly provided at the inner bottom of the slot 1 (2), and a plurality of grooves (15) are provided on the surface of the mounting seat (5) at equal intervals for the plate body (401) to be clamped, and the internal dimensions of the grooves (15) are all adapted to the external dimensions of the plate body (401).

6. The microplate reader with a pre-drying treatment mechanism according to claim 1, characterized in that: An isolation net (14) is fixedly provided on the inner side walls of the two notches (12), and the isolation net (14) is made of stainless steel and is in a grid shape.