Non-contact pipetting device
By using a piston rod to insert it into the pipetting chamber in the pipetting device, combined with the air intake interface and the first valve setting, the pump structure is cancelled, and the problems of complex structure and insufficient pipetting accuracy in the prior art are solved, and a high-precision and reliable pipetting effect is achieved.
Patent Information
- Application Number
- CN202422379676.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-09-29
- Publication Date
- 2025-08-15
- Estimated Expiration
- 2034-09-29
AI Technical Summary
The existing non-contact pipetting device has complex structures, low integration, and the pipetting accuracy is affected by the pipeline system.
The design of the piston rod being inserted into the pipetting chamber is adopted, and the suction force is generated by the piston rod being away from the pipetting chamber. Combined with the setting of the air intake interface and the first valve, the pump structure is cancelled, the pressure transmission path is shortened, and the pressure stability is improved.
Improve the pipetting accuracy, avoid the liquid being contaminated by the system fluid, and enhance the reliability and adaptability of the device.
Smart Images

Figure CN223221538U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of scientific instruments, in particular to a non-contact liquid transfer device. Background Art
[0002] Liquid handling devices are commonly used in laboratories to transfer small or trace amounts of liquid. Existing non-contact liquid handling devices typically include independent functional modules such as solenoid valves and pipette pumps. The low level of integration between these modules hinders their miniaturization. Furthermore, because these modules must be connected to the pipette needle via a piping system, unstable pressure transmission in the piping can easily affect the device's accuracy. Utility Model Content
[0003] Based on this, it is necessary to provide a non-contact pipetting device to address the technical problems in the prior art, such as the complex structure, low integration, and the influence of the pipetting accuracy on the pipe system.
[0004] A non-contact liquid transfer device, comprising:
[0005] The pipetting assembly comprises a base body and a pipetting needle, wherein the base body is provided with an air inlet interface and a pipetting cavity, the air inlet interface is used to communicate with an air source, and the pipetting needle is provided on the base body and is used to communicate with the pipetting cavity;
[0006] A drive assembly, comprising a piston rod, wherein the piston rod is inserted into the pipetting cavity and abuts against a cavity wall of the pipetting cavity; and
[0007] a first valve, disposed on the base, wherein an inlet of the first valve is used to communicate with the air inlet interface, and an outlet of the first valve is used to communicate with the pipetting chamber;
[0008] The piston rod is used to move along the pipetting cavity away from the pipetting needle when the first valve is closed, so that the target liquid enters the pipetting cavity through the pipetting needle; and
[0009] The air inlet interface is used for allowing the gas generated by the air source to enter the pipetting cavity through the air inlet interface when the first valve is opened, so that the target liquid in the pipetting cavity is discharged through the pipetting needle.
[0010] In one embodiment, the non-contact pipetting device further includes a second valve, which is mounted on the base, wherein an inlet of the second valve is used to communicate with the pipetting chamber, and an outlet of the second valve is used to communicate with the pipetting needle.
[0011] In one embodiment, the pipetting assembly also includes a first sealing ring, the pipetting chamber has an opening for inserting the piston rod, and a first groove is provided at one end of the base body close to the opening. The first groove is connected to the pipetting chamber and is circumferentially arranged around the pipetting chamber. The first sealing ring is sleeved on the piston rod and accommodated in the first groove. The inner side of the first sealing ring abuts against the piston rod, and the first sealing ring abuts against the groove wall of the first groove to seal the gap between the piston rod and the opening of the pipetting chamber.
[0012] In one embodiment, the base includes a first main body portion and a second main body portion that are detachably connected, the opening is arranged on the first main body portion, the first groove is arranged on the side of the second main body portion facing the first main body portion, and the first sealing ring is accommodated in the first groove and abuts against the first main body portion.
[0013] In one embodiment, the pipetting chamber includes a piston chamber and a liquid storage chamber that are interconnected, and the base also includes a third main body portion, which is detachably connected to the second main body portion. The piston chamber is arranged on the second main body portion, and the piston rod is inserted into the piston chamber. The liquid storage chamber is arranged in the third main body portion, and the liquid storage chamber is connected to the pipetting needle.
[0014] In one embodiment, the pipetting assembly further includes a second sealing ring, and one of the second main body portion and the third main body portion is provided with a second groove. The second sealing ring is accommodated in the second groove and abuts against the other of the second main body portion and the third main body portion to seal the gap between the second main body portion and the third main body portion.
[0015] In one embodiment, the pipetting chamber further includes a communicating hole, which is provided on the second main body portion and is respectively connected to the piston chamber and the liquid storage chamber, and the aperture of the communicating hole is smaller than the size of the piston chamber.
[0016] In one embodiment, the driving assembly further includes a driving member and an adapter, wherein the driving member is mounted on the base, the adapter is in transmission connection with the driving member and is connected to the piston rod, and the driving member is used to drive the adapter to move along the extension direction of the piston rod to drive the piston rod closer to or away from the pipette needle.
[0017] In one embodiment, the non-contact pipetting device further includes a position detection component, which includes a trigger plate and a position detector. The trigger plate is mounted on the adapter, and the position detector is mounted on the base and electrically connected to the driving component. When the adapter drives the trigger plate to approach a preset position relative to the pipetting needle, the position detector is triggered.
[0018] In one embodiment, a plurality of the pipetting cavities are provided on the base body at intervals, the number of the piston rods and the pipetting needles corresponds to the pipetting cavities, each pipetting needle is connected to the corresponding pipetting cavity, each piston rod is inserted into the corresponding pipetting cavity and connected to the adapter.
[0019] Beneficial effects:
[0020] The non-contact pipetting device provided by an embodiment of the utility model includes a pipetting component, a driving component and a first valve; the pipetting component includes a base body and a pipetting needle, the base body is provided with an air inlet interface and a pipetting cavity, the air inlet interface is used to communicate with an air source, the pipetting needle is arranged on the base body and is used to communicate with the pipetting cavity; the driving component includes a piston rod, the piston rod is inserted into the pipetting cavity and abuts against the cavity wall of the pipetting cavity; the first valve is arranged on the base body, the inlet of the first valve is used to communicate with the air inlet interface, and the outlet of the first valve is used to communicate with the pipetting cavity; the piston rod is used to move along the pipetting cavity away from the pipetting needle when the first valve is closed, so that the target liquid enters the pipetting cavity through the pipetting needle; and the air inlet interface is used to allow the gas generated by the air source to enter the pipetting cavity through the air inlet interface when the first valve is opened, so that the target liquid in the pipetting cavity is discharged through the pipetting needle.
[0021] In the present application, the piston rod is inserted into the pipetting chamber, and the piston rod is moved away from the pipetting chamber toward the pipetting needle to generate a suction force, so that the pipetting needle can draw the target liquid in the container into the pipetting chamber to achieve liquid aspiration, and the stable air pressure in the air inlet interface can generate a stable thrust, so that the volume of the target liquid discharged by the pipetting needle can be accurately controlled by controlling the time. That is, compared with the prior art, the pump structure is eliminated, and the first valve is arranged on the base, that is, near the pipetting chamber, so that the non-contact pipetting device in the present application does not introduce any pipeline system, thereby shortening the pressure transmission path, improving the stability of pressure transmission in the pipetting chamber, and thus improving the pipetting accuracy. BRIEF DESCRIPTION OF THE DRAWINGS
[0022] Figure 1 A schematic diagram of a contactless liquid transfer device according to an embodiment of the present invention.
[0023] Figure 2 A partial cross-sectional view of a non-contact liquid transfer device provided in one embodiment of the present invention.
[0024] Figure 3 for Figure 2 Enlarged view of point A in the middle.
[0025] Figure numbers: 100-pipetting assembly; 110-base; 111-first groove; 112-second groove; 113-second main body; 114-third main body; 120-air inlet interface; 130-pipetting chamber; 131-piston chamber; 132-liquid storage chamber; 133-connecting hole; 140-pipetting needle; 150-first main body; 151-opening; 160-first sealing ring; 170-second sealing ring; 200-driving assembly; 210-piston rod; 220-driving member; 230-adapter; 240-slider; 250-slide rail; 260-screw; 270-rotating block; 310-first valve; 311-first channel; 312-second channel; 320-second valve; 321-third channel; 322-fourth channel; 400-position detection member; 410-trigger plate; 420-position detector. DETAILED DESCRIPTION
[0026] To make the above-mentioned objects, features, and advantages of the present invention more clearly understood, the following detailed description of specific embodiments of the present invention is provided in conjunction with the accompanying drawings. The following description sets forth many specific details to facilitate a full understanding of the present invention. However, the present invention can be implemented in many other ways than those described herein, and those skilled in the art may make similar modifications without departing from the scope of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.
[0027] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like to indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation to the present invention.
[0028] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of the technical features being referred to. Thus, a feature specified as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of this utility model, "plurality" means at least two, such as two, three, etc., unless otherwise specifically defined.
[0029] In this utility model, unless otherwise specified or limited, the terms "installed," "connected," "connect," "fixed," etc. should be understood in a broad sense. For example, they can refer to fixed connection, detachable connection, or integration; mechanical connection, electrical connection; direct connection, or indirect connection through an intermediate medium; internal communication between two components, or interaction between two components, unless otherwise specified. Those skilled in the art will understand the specific meanings of the above terms in this utility model based on specific circumstances.
[0030] In the present invention, unless otherwise expressly specified or limited, when a first feature is "above" or "below" a second feature, it may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediary. Furthermore, when a first feature is "above," "above," or "above" a second feature, it may mean that the first feature is directly above or diagonally above the second feature, or simply means that the first feature is at a higher level than the second feature. When a first feature is "below," "below," or "below" a second feature, it may mean that the first feature is directly below or diagonally below the second feature, or simply means that the first feature is at a lower level than the second feature.
[0031] It should be noted that when an element is referred to as being "fixed to" or "disposed on" another element, it may be directly on the other element or there may be an intermediate element. When an element is considered to be "connected to" another element, it may be directly connected to the other element or there may be an intermediate element. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and similar expressions used herein are for illustrative purposes only and do not represent the only implementation methods.
[0032] See Figure 1 and Figure 2 , Figure 1 A schematic diagram of a contactless liquid transfer device according to an embodiment of the present invention. Figure 2A partial cross-sectional view of a non-contact liquid transfer device provided by an embodiment of the present invention. The non-contact liquid transfer device provided by an embodiment of the present invention includes a liquid transfer assembly 100, a drive assembly 200, and a first valve 310; the liquid transfer assembly 100 includes a base 110 and a pipetting needle 140, the base 110 is provided with an air inlet interface 120 and a liquid transfer cavity 130, the air inlet interface 120 is used to communicate with an air source, the pipetting needle 140 is provided on the base 110, and is used to communicate with the liquid transfer cavity 130; the drive assembly 200 includes a piston rod 210, the piston rod 210 is inserted into the liquid transfer cavity 130, and abuts against the cavity wall of the liquid transfer cavity 130; the first valve 310 Arranged on the base 110, the inlet of the first valve 310 is used to communicate with the air inlet interface 120, and the outlet of the first valve 310 is used to communicate with the pipetting chamber 130; the piston rod 210 is used to move along the pipetting chamber 130 away from the pipetting needle 140 when the first valve 310 is closed, so that the target liquid enters the pipetting chamber 130 through the pipetting needle 140; and the air inlet interface 120 is used to allow the gas generated by the gas source to enter the pipetting chamber 130 through the air inlet interface 120 when the first valve 310 is opened, so that the target liquid in the pipetting chamber 130 is discharged through the pipetting needle 140.
[0033] Specifically, in the present application, the piston rod 210 is inserted into the pipetting chamber 130. The piston rod 210 moves away from the pipetting chamber 130 toward the pipetting needle 140 to generate a suction force, thereby enabling the pipetting needle 140 to draw the target liquid in the container into the pipetting chamber 130 to achieve liquid aspiration. The stable air pressure in the air inlet port 120 generates a stable thrust, thereby accurately controlling the volume of the target liquid discharged by the pipetting needle 140 by controlling the time. That is, compared with the prior art, the pump structure is eliminated, and the first valve 310 is set on the base 110, that is, near the pipetting chamber 130. This makes the non-contact pipetting device in the present application not introduce a complex piping system, thereby shortening the pressure transmission path, improving the stability of pressure transmission in the pipetting chamber 130, and thus improving pipetting accuracy. The target liquid in the present application is at least one of a sample solution, a reagent solution, a sample and reagent mixture, and a cleaning solution.
[0034] It should be noted that, compared to the prior art method of moving the piston rod 210 relative to the pipetting chamber 130 toward the pipetting needle 140 to generate thrust, thereby causing the target liquid in the pipetting chamber 130 to be discharged through the pipetting needle 140, the present application can generate a stable thrust by passing a stable air pressure through the air inlet port 120. This allows the volume of the target liquid discharged by the pipetting needle 140 to be accurately controlled by controlling the time, thereby ensuring pipetting accuracy. Compared to the prior art method of using air to isolate the reagent and system fluid to achieve pressurization, the present application can prevent the target liquid from being contaminated by the system fluid.
[0035] Furthermore, the base 110 is provided with a first channel 311 and a second channel 312. One end of the first channel 311 communicates with the air inlet port 120, and the other end of the first channel 311 is configured to communicate with the inlet of the first valve 310. One end of the second channel 312 communicates with the outlet of the first valve 310, and the other end of the second channel 312 is configured to communicate with the pipetting chamber 130. When the first valve 310 is open, the pipetting chamber 130 communicates with the air inlet port 120, thereby facilitating the entry of compressed gas generated by the gas source into the pipetting chamber 130 via the air inlet port 120. When the first valve 310 is closed, the pipetting chamber 130 is disconnected from the air inlet port 120. The suction force generated by the piston rod 210 moving away from the pipetting chamber 130 toward the pipetting needle 140 is fully applied to the pipetting needle 140, thereby enabling the pipetting needle 140 to stably aspirate the target liquid within the container into the pipetting chamber 130. Preferably, the first valve 310 is a solenoid valve.
[0036] See Figure 1 and Figure 2 In one embodiment, the non-contact pipetting device further includes a second valve 320 , which is mounted on the base 110 , an inlet of the second valve 320 for communicating with the pipetting chamber 130 , and an outlet of the second valve 320 for communicating with the pipetting needle 140 .
[0037] Specifically, when the second valve 320 is in an open state, the pipetting needle 140 is in communication with the pipetting chamber 130, thereby enabling the pipetting needle 140 to aspirate the target liquid in the container into the pipetting chamber 130, or to discharge the target liquid in the pipetting chamber 130 through the pipetting needle 140. When the second valve 320 is in a closed state, the pipetting needle 140 is disconnected from the pipetting chamber 130, thereby enabling the target liquid to be stably stored in the pipetting chamber 130, thereby improving the reliability of the non-contact pipetting device. Preferably, the second valve 320 is a high-frequency solenoid valve.
[0038] Among them, during the liquid aspiration process, the first valve 310 is controlled to be closed and the second valve 320 is opened, and the piston rod 210 is moved along the pipetting chamber 130 away from the pipetting needle 140, so that the pipetting needle 140 can aspirate the target liquid in the container into the pipetting chamber 130; the second valve 320 is closed, and the target liquid is stably stored in the pipetting chamber 130; during the liquid spraying process, the first valve 310 is controlled to be opened, and compressed air enters the pipetting chamber 130 through the air inlet interface 120 to pressurize the target liquid in the pipetting chamber 130, and the second valve 320 is controlled to perform the switching action according to the set opening time and frequency, so that the target liquid in the pipetting chamber 130 is sprayed out under the joint action of the compressed air and the second valve 320, completing the pipetting process.
[0039] Furthermore, a third channel 321 and a fourth channel 322 are provided on the base 110, one end of the third channel 321 is connected to the pipetting chamber 130, and the other end of the third channel 321 is used to connect to the inlet of the first valve 310, one end of the fourth channel 322 is connected to the outlet of the first valve 310, and the other end of the fourth channel 322 is used to connect to the pipetting needle 140.
[0040] See Figure 1 and Figure 2 In one embodiment, the pipetting assembly 100 further includes a first sealing ring 160, the pipetting chamber 130 has an opening 151 for inserting the piston rod 210, and a first groove 111 is provided at one end of the base 110 close to the opening 151. The first groove 111 is communicated with the pipetting chamber 130 and is circumferentially arranged around the pipetting chamber 130. The first sealing ring 160 is sleeved on the piston rod 210 and accommodated in the first groove 111. The inner side of the first sealing ring 160 abuts against the piston rod 210, and the first sealing ring 160 abuts against the groove wall of the first groove 111 to seal the gap between the piston rod 210 and the opening 151 of the pipetting chamber 130.
[0041] Specifically, the arrangement of the first sealing ring 160 accommodated in the first groove 111 can limit the first sealing ring 160, so that the piston rod 210 can be stably limited in the first groove 111 when moving relative to the pipetting chamber 130. Because the first sealing ring 160 abuts against the piston rod 210 and the groove wall of the first groove 111, it can seal the gap between the piston rod 210 and the opening 151 of the pipetting chamber 130. This allows the piston rod 210 to move away from the pipetting needle 140, and the suction force generated can stably act on the pipetting needle 140, so that the pipetting needle 140 can stably aspirate the target liquid in the container into the pipetting chamber 130, thereby improving the reliability of the non-contact pipetting device.
[0042] See Figure 1 and Figure 2 In one embodiment, the base 110 includes a first main body portion 150 and a second main body portion 113 that are detachably connected, the opening 151 is set on the first main body portion 150, the first groove 111 is set on the side of the second main body portion 113 facing the first main body portion 150, and the first sealing ring 160 is accommodated in the first groove 111 and abuts against the first main body portion 150.
[0043] Specifically, the first groove 111 is provided on the side of the second body portion 113 facing the first body portion 150. The detachable connection between the first and second body portions 150, 113, facilitates the installation of the first sealing ring 160. The first sealing ring 160 is accommodated in the first groove 111 and abuts against the first body portion 150, allowing the first and second body portions 150, 113 to clamp the first sealing ring 160, thereby ensuring stable abutment between the first and second body portions 150, 113, and stably sealing the gap between the piston rod 210 and the opening 151 of the pipetting chamber 130. In other embodiments, the first groove 111 can be provided on the first body portion 150.
[0044] Furthermore, there are two second sealing rings 170 , which are arranged along the extension direction of the piston rod 210 , thereby forming a double seal, further improving the sealing between the piston rod 210 and the opening 151 of the pipetting chamber 130 .
[0045] See Figure 1 and Figure 2 In one embodiment, the pipetting chamber 130 includes a piston chamber 131 and a liquid storage chamber 132 that are interconnected. The base 110 also includes a third main body portion 114, which is detachably connected to the second main body portion 113. The piston chamber 131 is arranged on the second main body portion 113, and the piston rod 210 is inserted into the piston chamber 131. The liquid storage chamber 132 is arranged in the third main body portion 114, and the liquid storage chamber 132 is connected to the pipetting needle 140.
[0046] Specifically, by detachably connecting the second main body 113 and the third main body 114 , the piston chamber 131 and the liquid storage chamber 132 can be separately provided, thereby reducing the difficulty of processing the pipetting chamber 130 and facilitating the processing of the non-contact pipetting device.
[0047] Furthermore, a first valve 310 is connected to the second main body 113, and its outlet is in communication with the piston chamber 131. This allows compressed gas to enter the piston chamber 131 via the air inlet port 120 when the first valve 310 is open, thereby applying a stable thrust to the target liquid within the liquid storage chamber 132. A second valve 320 is connected to the third main body 114 and is located below the first valve 310. Its inlet is connected to the end of the liquid storage chamber 132 away from the piston chamber 131, thereby facilitating the discharge of the target liquid within the liquid storage chamber 132 via the pipette needle 140.
[0048] In other embodiments, the third main body portion 114 and the second main body portion 113 may also be integrally formed, thereby reducing the number of connecting parts between the third main body portion 114 and the second main body portion 113 and improving stability.
[0049] See Figure 1 and Figure 2 In one embodiment, the pipetting assembly 100 further includes a second sealing ring 170, and one of the second main body portion 113 and the third main body portion 114 is provided with a second groove 112. The second sealing ring 170 is accommodated in the second groove 112 and abuts against the other of the second main body portion 113 and the third main body portion 114 to seal the gap between the second main body portion 113 and the third main body portion 114.
[0050] Specifically, the arrangement of the second sealing ring 170 accommodated in the second groove 112 can limit the second sealing ring 170, and through the second sealing ring 170 abutting against the other of the second main body part 113 and the third main body part 114, the second sealing ring 170 is stably clamped by the second main body part 113 and the third main body part 114, so that the second sealing ring 170 is stably abutted against the second main body part 113 and the third main body part 114, thereby stably sealing the gap between the second main body part 113 and the third main body part 114, so that the piston rod 210 is away from the pipette needle 140 to generate a suction force that can stably act on the pipette needle 140, thereby improving the reliability of the non-contact pipetting device.
[0051] See Figure 1 ,and Figure 2 and Figure 3 , Figure 3 for Figure 2 Enlarged view of point A in the middle. In one embodiment, the pipetting chamber 130 further includes a communicating hole 133, which is disposed on the second main body 113 and communicates with the piston chamber 131 and the liquid storage chamber 132, respectively. The communicating hole 133 has a smaller diameter than the piston chamber 131, thereby limiting the piston rod 210 and preventing the piston rod 210 from extending into the liquid storage chamber 132 and contacting the target liquid, thereby improving the reliability of the non-contact pipetting device.
[0052] See Figure 1 and Figure 2 In one embodiment, the driving assembly 200 further includes a driving member 220 and an adapter 230. The driving member 220 is mounted on the base 110. The adapter 230 is transmission-connected to the driving member 220 and is also connected to the piston rod 210. The driving member 220 is used to drive the adapter 230 to move along the extension direction of the piston rod 210 to drive the piston rod 210 to move closer to or away from the pipette needle 140.
[0053] Specifically, the first valve 310 and the second valve 320 are disposed on the same side of the base 110, while the driver 220 is disposed on the side of the base 110 facing away from the first valve 310, thereby minimizing interference. The driver 220 drives the adapter 230 to move along the extension direction of the piston rod 210, thereby moving the piston rod 210 toward or away from the pipette needle 140. Preferably, the driver 220 is a motor.
[0054] Furthermore, the non-contact pipetting device also includes a controller, which is electrically connected to the driving member 220, the first valve 310 and the second valve 320. The controller can control the opening and closing of the driving member 220, the first valve 310 and the second valve 320. By controlling the opening time of the first valve 310 and the second valve 320, the amount of target liquid removed can be controlled.
[0055] See Figure 1 and Figure 2 In one embodiment, the drive assembly 200 further includes a slider 240 and a slide rail 250. The slide rail 250 is disposed on the base 110, and the slider 240 is disposed on the adapter 230. The slider 240 and the slide rail 250 are slidably connected along the extension direction of the piston rod 210, thereby playing a guiding role, so that the adapter 230 can stably drive the piston rod 210 to move along the extension direction of the piston rod 210.
[0056] Furthermore, the drive assembly 200 also includes a screw 260 and a rotating block 270. The screw 260 is transmission-connected to the drive member 220. The adapter block is threadedly connected to the screw 260 and connected to the adapter 230. The drive member 220 is used to drive the screw 260 to rotate, thereby driving the mounting block to drive the adapter 230 to move.
[0057] See Figure 1 and Figure 2 In one embodiment, the non-contact pipetting device further includes a position detection component 400, which includes a trigger piece 410 and a position detector 420. The trigger piece 410 is mounted on the adapter 230, and the position detector 420 is mounted on the base 110 and electrically connected to the driving component 220. When the adapter 230 drives the trigger piece 410 to approach a preset position relative to the pipetting needle 140, the position detector 420 is triggered.
[0058] Specifically, the controller is electrically connected to the position detector 420. When the adapter 230 drives the trigger plate 410 to approach the predetermined position relative to the pipette needle 140, the position detector 420 is triggered, causing the controller to control the driver 220 to close, thereby resetting the piston rod 210 and preparing for the next aspiration. Preferably, the position detector 420 is a photoelectric sensor.
[0059] See Figure 1 and Figure 2 In one embodiment, a plurality of spaced-apart pipetting cavities 130 are provided on the base body 110, and the number of piston rods 210 and pipetting needles 140 corresponds to the number of the pipetting cavities 130, each pipetting needle 140 is connected to the corresponding pipetting cavity 130, and each piston rod 210 is inserted into the corresponding pipetting cavity 130 and connected to the adapter 230.
[0060] Specifically, the number of first valves 310, second valves 320 and air inlet interfaces 120 corresponds to the number of pipetting chambers 130. When the driving member 220 drives the adapter 230 to move, the adapter 230 can drive each piston rod 210 to move relative to the corresponding piston chamber 131, thereby realizing liquid aspiration through the corresponding pipetting needles 140, and the compressed gas introduced through each air inlet interface 120 to realize the discharge of the target liquid in each liquid storage chamber 132, so that different target liquids can be pipetted, thereby improving the adaptability of the non-contact pipetting device.
[0061] In other embodiments, the number of driving members 220 and adapter members 230 may correspond to the number of pipetting chambers 130 , that is, each pipetting chamber 130 corresponds to a driving source.
[0062] The workflow of the non-contact pipetting device in this application is as follows:
[0063] The controller controls the first valve 310 to close and the second valve 320 to open. The controller also controls the driver 220 to open, so that the driver 220 drives the piston rod 210 toward the pipetting needle 140 until the trigger plate 410 triggers the photoelectric sensor. The controller then controls the driver 220 to stop working, and the non-contact pipetting device completes the initialization preparation for liquid aspiration.
[0064] The first container containing the target liquid is placed under the pipetting needle 140, and the pipetting needle 140 is positioned below the liquid surface of the target liquid. The driving member 220 drives the piston rod 210 to move away from the pipetting needle 140, so that the pipetting needle 140 aspirates an appropriate amount of the target liquid into the liquid storage chamber 132. Then, the controller controls the second valve 320 to close, removing the pipetting needle 140 from the target liquid, and the aspiration process is completed.
[0065] The second container for receiving the target liquid is placed under the pipetting needle 140, and the controller controls the first valve 310 to open. Compressed air enters the pipetting chamber 130 through the air inlet interface 120, pressurizing the target liquid in the liquid storage chamber 132. Then, the controller controls the second valve 320 to perform the switching action according to the set opening time and frequency. The target liquid in the liquid storage chamber 132 is ejected under the joint action of the compressed air and the second valve 320, completing the pipetting process.
[0066] The technical features of the above-mentioned embodiments can be combined arbitrarily. In order to make the description concise, not all possible combinations of the technical features in the above-mentioned embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.
[0067] The above-described embodiments merely represent several implementations of the present invention. While the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the utility model patent. It should be noted that a person skilled in the art would be able to make various modifications and improvements without departing from the concept of the present invention, and these modifications and improvements fall within the scope of protection of the present invention. Therefore, the scope of protection of the present utility model patent shall be determined by the appended claims.
Claims
1. A non-contact liquid transfer device, characterized in that: The non-contact liquid transfer device comprises: The pipetting assembly comprises a base body and a pipetting needle, wherein the base body is provided with an air inlet interface and a pipetting cavity, the air inlet interface is used to communicate with an air source, and the pipetting needle is provided on the base body and is used to communicate with the pipetting cavity; A drive assembly, comprising a piston rod, wherein the piston rod is inserted into the pipetting cavity and abuts against a cavity wall of the pipetting cavity; and a first valve, disposed on the base, wherein an inlet of the first valve is used to communicate with the air inlet interface, and an outlet of the first valve is used to communicate with the pipetting chamber; The piston rod is used to move along the pipetting chamber away from the pipetting needle when the first valve is closed, so that the target liquid enters the pipetting chamber through the pipetting needle; and the air inlet interface is used to allow the gas generated by the air source to enter the pipetting chamber through the air inlet interface when the first valve is opened, so that the target liquid in the pipetting chamber is discharged through the pipetting needle.
2. The non-contact pipetting device according to claim 1, characterized in that The non-contact pipetting device further includes a second valve, which is mounted on the base. The inlet of the second valve is used to communicate with the pipetting chamber, and the outlet of the second valve is used to communicate with the pipetting needle.
3. The non-contact liquid transfer device according to claim 1, wherein: The pipetting assembly also includes a first sealing ring, the pipetting chamber has an opening for inserting the piston rod, and a first groove is provided at one end of the base body close to the opening. The first groove is connected to the pipetting chamber and is circumferentially arranged around the pipetting chamber. The first sealing ring is sleeved on the piston rod and accommodated in the first groove. The inner side of the first sealing ring abuts against the piston rod, and the first sealing ring abuts against the groove wall of the first groove to seal the gap between the piston rod and the opening of the pipetting chamber.
4. The non-contact liquid transfer device according to claim 3, characterized in that: The base includes a first main body and a second main body that are detachably connected. The opening is arranged on the first main body. The first groove is arranged on a side of the second main body facing the first main body. The first sealing ring is accommodated in the first groove and abuts against the first main body.
5. The non-contact liquid transfer device according to claim 4, characterized in that: The pipetting chamber includes a piston chamber and a liquid storage chamber that are interconnected. The base also includes a third main body portion, which is detachably connected to the second main body portion. The piston chamber is arranged on the second main body portion, and the piston rod is inserted into the piston chamber. The liquid storage chamber is arranged in the third main body portion, and the liquid storage chamber is connected to the pipetting needle.
6. The non-contact liquid transfer device according to claim 5, characterized in that: The pipetting assembly also includes a second sealing ring. One of the second main body and the third main body is provided with a second groove. The second sealing ring is accommodated in the second groove and abuts against the other of the second main body and the third main body to seal the gap between the second main body and the third main body.
7. The non-contact pipetting device according to claim 5, characterized in that The pipetting chamber further includes a communicating hole, which is provided on the second main body portion and is respectively communicated with the piston chamber and the liquid storage chamber. The aperture of the communicating hole is smaller than the size of the piston chamber.
8. The contactless pipetting device according to any one of claims 1 to 7, characterized in that: The driving assembly also includes a driving member and an adapter. The driving member is installed on the base. The adapter is in transmission connection with the driving member and is connected to the piston rod. The driving member is used to drive the adapter to move along the extension direction of the piston rod to drive the piston rod closer to or away from the pipette needle.
9. The non-contact liquid transfer device according to claim 8, characterized in that: The non-contact pipetting device also includes a position detection component, which includes a trigger piece and a position detector. The trigger piece is installed on the adapter, and the position detector is installed on the base and electrically connected to the driving component. When the adapter drives the trigger piece to approach a preset position relative to the pipetting needle, the position detector is triggered.
10. The non-contact pipetting device according to claim 8, characterized in that: The base is provided with a plurality of pipetting cavities arranged at intervals, the number of the piston rods and the pipetting needles corresponds to the pipetting cavities, each pipetting needle is connected to the corresponding pipetting cavity, each piston rod is inserted into the corresponding pipetting cavity and connected to the adapter.
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Pipetting device
CN121571223A