Fermentation reaction kettle for preparing L-valine

Abstract

The utility model relates to a fermentation reaction kettle, in particular to a fermentation reaction kettle for preparing L-valine. Comprising a base, a mounting seat, a heat furnace, a steam pipe, a fermentation container and the like, a mounting seat is fixedly connected to the upper part of the base, a heating furnace is fixedly connected in the mounting seat, steam pipes are connected to the left and right sides of the upper part of the heating furnace, the two steam pipes are communicated with the interior of the heating furnace, and a fermentation container is arranged in the heating furnace. By arranging the intelligent detection system, physical parameters, chemical parameters and biological and biochemical parameters in the fermentation container are automatically detected and monitored in real time and are displayed through the display screen, the fermentation process is monitored in real time through the parameters fed back in the display screen, whether fermentation in the fermentation kettle reaches an expected target or not is judged, and the fermentation efficiency is improved. Fermentation conditions are timely terminated or adjusted to ensure that the fermentation conditions are in an optimal state, so that the product quality and yield are improved.

Description

Technical Field

[0001] The utility model relates to a fermentation reactor, in particular to a fermentation reactor for preparing L-valine. Background Art

[0002] L-valine is often produced by microbial fermentation.

[0003] Generally, L-valine production is increased by selecting high-yield strains and optimizing fermentation conditions: selecting high-yield strains is to screen out strains that can efficiently produce L-valine through specific technical means; while optimizing fermentation conditions involves controlling multiple factors such as temperature, pH value, oxygen supply, and the ratio of nutrients during the fermentation process to ensure that the strain grows and produces L-valine under optimal conditions.

[0004] At present, the detection of fermentation conditions inside the fermentation kettle is basically carried out by manual timed detection. There is a certain lag between the detection results of the detection system and the actual situation. The use of indirect data to control various conditions in the fermentation kettle cannot effectively cope with the complexity of biological reactions in the fermentation liquid, and it is difficult to ensure the accuracy of various conditions when manually intervened. Therefore, it is very easy to cause the fermentation conditions in the fermentation kettle to be unstable, making it difficult to ensure that the fermentation conditions are in the best state, and the product quality and output cannot be guaranteed. Utility Model Content

[0005] In order to overcome the shortcomings of a certain lag between the detection results of the detection system and the actual situation, the inability to effectively cope with the complexity of biological reactions in the fermentation liquid, the difficulty in ensuring the accuracy of various condition adjustments during manual intervention, and the high risk of unstable fermentation conditions in the fermentation kettle, making it difficult to ensure that the fermentation conditions are in an optimal state, and the inability to guarantee product quality and output, the purpose is to provide a fermentation reactor for L-valine preparation that can provide real-time feedback of the detection results in the detection module.

[0006] The technical solution of the utility model is: a fermentation reactor for preparing L-valine, comprising a base, a mounting base, a heating furnace, a steam pipe, a fermentation container, a discharge pipe, a stirring member, a feed inlet, a detector, a display screen and a detection module; the upper part of the base is fixedly connected to the mounting base, the heating furnace is fixedly connected to the mounting base, the left and right sides of the upper part of the heating furnace are connected to steam pipes, the two steam pipes are connected to the interior of the heating furnace, a fermentation container is arranged inside the heating furnace, an air barrier is formed between the outer wall of the fermentation container in the heating furnace and the inner wall of the heating furnace, a discharge pipe is arranged on the left side of the lower part of the fermentation container, and the lower part of the discharge pipe penetrates into the base A feed port is provided on the left upper part of the fermentation container, and the discharge pipe and the feed port are normally closed. A stirring member is provided concentrically on the upper part of the fermentation container, and the stirring member consists of a driving motor and a stirring frame. The stirring frame is provided with no less than one stirring fan blade, and the stirring frame of the stirring member extends into the interior of the fermentation container. No less than two detectors are provided on the right upper part of the fermentation container, and the probes of the detectors are all extended into the interior of the fermentation container. A display screen is installed on the right front part of the hot furnace, and a detection module is installed on the upper left part of the fermentation container. The detection module is connected to the detector signal and outputs the signal transmitted by the detector to the display screen.

[0007] Preferably, a drawer-type filter element and a pipe joint are also included. A drawer-type filter element is slidingly provided on the inner side of the base. The drawer-type filter element is composed of an outer shell and multiple layers of filter membranes. The discharged material in the discharge pipe will flow into the drawer-type filter element. The lower part of the drawer-type filter element is connected and communicated with a pipe joint.

[0008] Preferably, a thermostat is further included, and the left steam pipe is connected to the thermostat.

[0009] Preferably, a self-priming impeller is further included, and the stirring frame of the stirring member is provided with the self-priming impeller.

[0010] Preferably, a peek window is further included, and a peek window is provided on the front upper side of the fermentation container.

[0011] Preferably, an optical instrument is further included, and the peep window is equipped with the optical instrument, with the optical lens of the optical instrument facing the peep window.

[0012] Preferably, a flamethrower is further included, and a flamethrower is arranged on the periphery of the feed port.

[0013] The beneficial effects are as follows: 1. The utility model realizes automatic detection by setting up an intelligent detection system, monitors the physical parameters, chemical parameters and biological and biochemical parameters in the fermentation container in real time, and displays them on the display screen. Through the parameters fed back on the screen, the fermentation process is monitored in real time, and it is judged whether the fermentation in the fermentation kettle has reached the expected goal, and the fermentation conditions are terminated or adjusted in time to ensure that the fermentation conditions are in the best state, thereby improving product quality and output.

[0014] 2. The utility model realizes uniform mixing of gas and liquid in the fermentation kettle through the self-priming impeller provided on the stirring member, effectively enhances the shear force and mixing ability of the fluid, and achieves a uniform and stable mixing effect for the contents in the fermentation container.

[0015] 3. The utility model provides a drawer-type filter at the discharge pipe of the fermentation kettle to quickly filter and separate the fermentation liquid discharged from the fermentation kettle. Through pretreatment, impurities and microorganisms in the fermentation liquid are removed, which is conducive to the smooth progress of subsequent processes such as extraction and refining.

[0016] 4. When the seed liquid is injected into the fermentation kettle, the flame ejected by the flamethrower isolates the feed port and the external space around the feed port, preventing external microorganisms from entering when the feed port is opened for feeding, affecting the normal reaction of the fermentation liquid, and ensuring that the fermentation conditions in the fermentation kettle are at their best. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model.

[0018] Figure 2 This is a schematic diagram of the three-dimensional structure of the present invention without the fermentation reaction component.

[0019] Figure 3 This is a schematic diagram of the three-dimensional structure of the present invention without the temperature control component.

[0020] Figure 4 It is a three-dimensional structural diagram of the fermentation container, feed port, detector and other components of the utility model.

[0021] Figure 5 It is a three-dimensional structural diagram of the base, drawer-type filter element and pipe joint of the utility model.

[0022] Figure 6 It is a three-dimensional structural diagram of the stirring element and the self-priming impeller of the utility model.

[0023] Reference numerals: 1-base, 2-mounting seat, 3-heat furnace, 31-steam pipe, 4-fermentation container, 41-discharge pipe, 42-stirring element, 43-feed port, 44-detector, 5-display screen, 51-detection module, 6-drawer filter element, 61-pipe joint, 7-thermostat, 8-self-priming impeller, 10-peep window, 11-optical instrument, 12-flamethrower. DETAILED DESCRIPTION

[0024] The present invention will be described in detail below with reference to the accompanying drawings.

[0025] Example 1: A fermentation reactor for preparing L-valine, such as Figure 1-6As shown, it includes a base 1, a mounting base 2, a heating furnace 3, a steam pipe 31, a fermentation container 4, a discharge pipe 41, a stirring member 42, a feed port 43, a detector 44, a display screen 5 and a detection module 51. The mounting base 2 is firmly welded to the upper part of the base 1. The base 1 and the mounting base 2 are stable bases made of metal and are used to support all components of the fermentation kettle. The heating furnace 3 that provides fermentation temperature for the fermentation container 4 is fixedly connected to the mounting base 2. The left and right sides of the upper part of the heating furnace 3 are connected to the steam pipes 31. The two steam pipes 31 are both connected to the interior of the heating furnace 3. The steam connected from the outside will enter the heating furnace 3 through the steam pipe 31 on the left and be discharged through the steam pipe 31 on the right. The temperature of the steam connected to the steam pipe 31 should be a temperature suitable for the fermentation reaction of the L-valine fermentation liquid.

[0026] A fermentation container 4 for storing fermentation liquid is provided inside the hot furnace 3. An air barrier is formed between the outer wall of the fermentation container 4 in the hot furnace 3 and the inner wall of the heating furnace 3 so that steam can effectively contact the outer wall of the fermentation container 4. The steam temperature is conducted to the fermentation container 4 through heat transfer. A discharge pipe 41 for discharging the fermentation liquid is provided on the left side of the lower part of the fermentation container 4. The lower part of the discharge pipe 41 penetrates into the base 1, and the discharge pipe 41 can be connected to an external pipeline. A feed port 43 for injecting the seed liquid required for fermentation into the fermentation container 4 is provided on the left side of the upper part of the fermentation container 4. Both the discharge pipe 41 and the feed port 43 are normally closed. A stirring member 42 for mixing and stirring the fermented liquid is provided concentrically on the upper part of the fermentation container 4. The stirring member 42 consists of a driving motor and a stirring frame. The mixing frame is provided with at least one stirring blade, the rotation speed of the driving motor of the stirring member 42 is adjustable, the stirring frame of the stirring member 42 extends into the interior of the fermentation container 4, the stirring blade of the stirring member 42 should be immersed in the fermentation liquid, and the fermentation liquid is stirred and mixed by the rotation of the stirring frame, and an air path should be arranged at the lower part of the fermentation container 4, which will discharge gas into the fermentation liquid and provide the fermentation liquid in the fermentation container 4 with the oxygen required for the reaction. At least two detectors 44 are provided on the right side of the upper part of the fermentation container 4, and the probes of the detectors 44 are all extended into the interior of the fermentation container 4. The detectors 44 are used to monitor the chemical parameters in the fermentation container 4: enzyme activity and the content of enzyme activity inhibitors; fermentation kinetic parameters: including temperature, pH value, dissolved oxygen, stirring speed, etc.

[0027] A display screen 5 is installed on the front right side of the hot furnace 3, and a detection module 51 is installed on the upper left side of the fermentation container 4. The detection module 51 is connected to the detector 44 signal. The detection module 51 collects the detection data in all the detectors 44 and outputs the model transmitted by the detector 44 to the display screen 5 in real time to realize automatic detection, monitor the physical parameters, chemical parameters and biological and biochemical parameters in the fermentation container in real time, and display them through the display screen 55. Through the parameters fed back on the screen, the fermentation process is monitored in real time to judge whether the fermentation in the fermentation kettle has reached the expected goal, terminate or adjust the fermentation conditions in time to ensure that the fermentation conditions are in the best state, thereby improving product quality and output.

[0028] Example 2: Based on Example 1, Figure 1 、 Figure 3 and amount Figure 5 As shown, it also includes a drawer-type filter element 6 and a pipe joint 61. A drawer-type filter element 6 for pre-treating the fermentation liquid is slidingly provided on the inner side of the base 1. The drawer-type filter element 6 consists of a square outer shell and multiple layers of filter membranes arranged up and down inside. The discharged material in the discharge pipe 41 will flow into the drawer-type filter element 6, and the fermentation liquid is filtered through the multiple layers of filter membranes. The impurities and microorganisms in the fermentation liquid are removed through the filter component arranged at the discharge of the fermentation kettle, which is conducive to the smooth progress of subsequent processes such as extraction and refining. The lower part of the drawer-type filter element 6 is connected and communicated with a pipe joint 61, which is connected to the external pipe through the pipe joint 61 to transmit the filtered liquid to the next processing station.

[0029] In a specific embodiment: Figure 1 and Figure 2 As shown, a thermostat 7 is also included. The steam pipe 31 on the left is connected to the thermostat 7 to ensure the temperature of the steam entering the hot furnace 3 is stable. The thermostat 7 is composed of a temperature control module, a regulator, a thermostat, etc. The thermostat is composed of a glass cylinder or a metal pot, which contains liquid to maintain a constant temperature environment.

[0030] When steam is connected, it will fluctuate due to interference from external factors during the transmission process. When the steam is transmitted into the hot furnace 3, the steam temperature may be too high or too low and cannot meet the requirements of use. The steam temperature is adjusted and controlled by the set constant temperature component to ensure that the temperature in the fermentation container 4 is at a normal state.

[0031] In a specific embodiment: Figure 6 As shown, a self-priming impeller 8 is also included. The stirring frame of the stirring member 42 is provided with a self-priming impeller 8. The self-priming impeller 8 is composed of a turbine blade and an annular gas distributor. The vacuum generated when the specially shaped turbine blade rotates will suck the gas discharged from the gas path in the fermentation container 4 into the liquid upward, further enhancing the mass transfer effect of the gas in the liquid and ensuring that the gas and the fermentation liquid are evenly mixed.

[0032] In a specific embodiment: Figure 1 、 Figure 3 and Figure 4 As shown, a peep window 10 is also included. A peep window 10 is opened on the front side of the upper part of the fermentation container 4. A transparent block is provided on the peep window 10. The interior of the fermentation container 4 can be directly observed through the transparent block. The peep window 10 can help the operator observe the fermentation process in the fermentation container 4 without interfering with the normal fermentation.

[0033] In a specific embodiment, Figure 1 、 Figure 3 and Figure 4 As shown, an optical instrument 11 is also included. The optical instrument 11 is installed on the peek window 10. The optical instrument 11 is connected to the display screen 5 by signal. The optical lens of the optical instrument 11 is facing the peek window 10. The optical instrument 11 on the peek window 10 will transmit the situation in the fermentation container 4 to the display screen 5 in real time. By providing intuitive visual information, it helps the operator to better control and optimize the fermentation process and ensure the quality and output of the product.

[0034] In a specific embodiment: Figure 1 、 Figure 3 and Figure 4 As shown, a flamethrower 12 is also included. The flamethrower 12 is arranged around the feed port 43. There are multiple flamethrowers 12 surrounding the feed port 43. When the seed liquid is injected into the fermentation kettle, the flame ejected by the flamethrower 12 isolates the feed port 43 and the external space around the feed port 43, thereby preventing external microorganisms from entering the fermentation container 4 when the feed port 43 is opened for feeding, affecting the normal reaction of the fermentation liquid, and ensuring that the fermentation conditions in the fermentation container 4 are at their best.

[0035] While the present invention has been described with reference to exemplary embodiments, it should be understood that the invention is not limited to the disclosed exemplary embodiments. The scope of the following claims is to be accorded the broadest interpretation so as to encompass all modifications and equivalent structures and functions.

Claims

1. A fermentation reactor for preparing L-valine, comprising a base (1), a mounting base (2), a heating furnace (3) and a steam pipe (31), wherein the upper portion of the base (1) is fixedly connected to the mounting base (2), the heating furnace (3) is fixedly connected inside the mounting base (2), and the upper left and right sides of the heating furnace (3) are both connected to steam pipes (31), and both steam pipes (31) are communicated with the interior of the heating furnace (3); It is characterized in that The invention also includes a fermentation container (4), a discharge pipe (41), a stirring member (42), a feed port (43), a detector (44), a display screen (5) and a detection module (51). The fermentation container (4) is arranged inside the heating furnace (3). An air barrier is formed between the outer wall of the fermentation container (4) in the heating furnace (3) and the inner wall of the heating furnace (3). A discharge pipe (41) is arranged on the left side of the lower part of the fermentation container (4). The lower part of the discharge pipe (41) penetrates into the base (1). A feed port (43) is arranged on the left side of the upper part of the fermentation container (4). Both the discharge pipe (41) and the feed port (43) are normally closed. A concentric valve is arranged on the upper part of the fermentation container (4). A stirring member (42) is provided, the stirring member (42) is composed of a driving motor and a stirring frame, the stirring frame is provided with at least one stirring fan blade, the stirring frame of the stirring member (42) extends into the interior of the fermentation container (4), at least two detectors (44) are provided on the right side of the upper part of the fermentation container (4), the probes of the detectors (44) are all extended into the interior of the fermentation container (4), a display screen (5) is installed on the right side of the front part of the hot furnace (3), a detection module (51) is installed on the upper left part of the fermentation container (4), the detection module (51) is connected to the detector (44) signal, and outputs the signal transmitted by the detector (44) to the display screen (5).

2. A fermentation reactor for preparing L-valine according to claim 1, characterized in that, The invention also includes a drawer-type filter element (6) and a pipe joint (61). The drawer-type filter element (6) is slidably provided on the inner side of the base (1). The drawer-type filter element (6) is composed of an outer shell and a multi-layer filter membrane. The discharged material in the discharge pipe (41) will flow into the drawer-type filter element (6). The lower part of the drawer-type filter element (6) is connected and communicated with the pipe joint (61).

3. A fermentation reactor for preparing L-valine according to claim 2, characterized in that: The utility model further comprises a thermostat (7), and the thermostat (7) is connected to the steam pipe (31) on the left side.

4. A fermentation reactor for preparing L-valine according to claim 3, characterized in that: It also includes a self-priming impeller (8), and the stirring frame of the stirring member (42) is provided with the self-priming impeller (8).

5. A fermentation reactor for preparing L-valine according to claim 4, characterized in that: The fermentation container (4) further comprises a peek window (10), which is provided on the front side of the upper portion of the fermentation container (4).

6. A fermentation reactor for preparing L-valine according to claim 5, characterized in that: The invention also comprises an optical instrument (11), which is installed on the peep window (10), and an optical lens of the optical instrument (11) faces the peep window (10).

7. A fermentation reactor for preparing L-valine according to claim 6, characterized in that: The invention also comprises a flamethrower (12), and the flamethrower (12) is arranged on the periphery of the feed port (43).

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