96-well plate experimental device

Through the split-shaped 96-well plate experimental device, the problems of high mold opening costs and waste of hole fillers were solved, and the convenience of cost reduction and liquid level observation was achieved.

CN223255202UActive Publication Date: 2025-08-22NAOU TECH (SHANXI) CO LTD
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Patent Information

Application Number
CN202421484051.1
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-26
Publication Date
2025-08-22
Estimated Expiration
2034-06-26

AI Technical Summary

Technical Problem

The existing 96-well plate mold opening costs are high, the hole filler is wasteful and the liquid level is inconvenient.

Method used

The split 96-well plate experimental device is designed, including a combined structure of the base plate, top plate, support rod, bottom plate hole, top plate hole and SPE column, allowing for the disassembly and flexibility of the SPE column, combining slopes and grip blocks for easy operation.

Benefits of technology

It reduces mold opening costs, reduces waste of hole fillers, and facilitates observation of liquid level passing.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the field of experimental equipment, in particular to a 96-well plate experimental device. The 96-pore plate experimental device comprises a bottom plate and a top plate, supporting rods which are respectively positioned at four corners are matched between the bottom plate and the top plate, 96 bottom plate holes are uniformly formed in the bottom plate at intervals, 96 top plate holes are formed in the top plate, and each top plate hole vertically corresponds to one bottom plate hole; the upper end of the SPE small column is matched with the top plate hole, and the lower end of the SPE small column is matched with the bottom plate hole. According to the 96-well plate experimental device disclosed by the utility model, the bottom plate, the top plate, the supporting rods, the bottom plate holes, the top plate holes, the SPE small columns and the like are matched, so that compared with an integrated mold opening 96-well plate experimental device in the prior art, the 96-well plate experimental device does not need mold opening, and the cost can be reduced; a corresponding number of SPE small columns can be used according to actual experiment requirements, so that the waste of the hole filler is reduced; no plastic plate hinders sight, and liquid level passing conditions can be observed conveniently.
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Description

Technical Field

[0001] The utility model relates to the field of experimental equipment, in particular to a 96-well plate experimental device. Background Art

[0002] The 96-well plate is a common laboratory tool. Typically made of optically transparent polystyrene, which ensures excellent cell adhesion, these plates are commonly used to culture cells such as neurons and tumor cells. In ELISA experiments, 96-well plates are used to immobilize antibodies or antigens and are a key component of the experimental process. They are also used in a variety of other experiments, such as PCR and drug discovery. When conducting experiments using 96-well plates, aseptic techniques must be observed to ensure the sterility of cells, culture medium, and laboratory equipment.

[0003] The main issues with existing 96-well plates are: 1. The mold cost for a 96-well plate is high, costing between 50,000 and 100,000 yuan per plate. 2. During use, if 96 samples are not processed at once, the remaining well fillers are wasted. 3. The thick plastic walls of the well plates make it difficult to observe the liquid level.

[0004] Therefore, it is necessary to design a new 96-well plate experimental device to reduce costs, reduce waste of well fillers and facilitate observation of liquid level passing. Utility Model Content

[0005] In view of the defects in the prior art, the utility model provides a 96-well plate experimental device which reduces costs, reduces waste of well fillers and facilitates observation of the liquid level passing through.

[0006] The technical solution adopted by the utility model is: a 96-well plate experimental device, including a bottom plate and a top plate, support rods respectively located at four corners are matched between the bottom plate and the top plate, 96 bottom plate holes are evenly spaced on the bottom plate, 96 top plate holes are arranged on the top plate, and each top plate hole vertically corresponds to a bottom plate hole; and an SPE column is also included, the upper end of the SPE column is matched with the top plate hole, and the lower end is matched with the bottom plate hole.

[0007] In order to better realize the present invention, the top plate includes a lower plate and an upper plate detachably connected to the top surface of the lower plate, and the bottom surface of the lower plate is connected to the support rod; the top plate hole passes through the upper plate and the lower plate, and the top of the SPE column is provided with a clamping portion with an effective diameter larger than the effective diameter of the top plate hole.

[0008] In order to better realize the present invention, downwardly inclined slopes are provided on both sides of the top surface of the lower plate, and a gap is formed between the slope and the upper plate to facilitate the removal of the upper plate.

[0009] In order to better realize the present invention, gripping blocks are provided on both sides of the top surface of the bottom plate.

[0010] In order to better realize the present utility model, anti-slip lines are provided on the gripping block.

[0011] In order to better realize the present invention, the bottom end of the support rod is threadedly matched with the bottom plate.

[0012] The beneficial effects of the present invention are as follows: the 96-well plate experimental device of the present invention, through the coordination of the bottom plate, the top plate, the support rods, the bottom plate holes, the top plate holes and the SPE columns, does not require mold making compared to the 96-well plate experimental device with an integrated mold in the prior art, which can reduce costs; a corresponding number of SPE columns can be used according to actual experimental needs, reducing waste of well fillers; there is no thick plastic plate to block the line of sight, which can facilitate observation of the liquid level passing through. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] To more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the following briefly describes the drawings required for the specific embodiments or the description of the prior art. Similar elements or parts are generally identified by similar reference numerals throughout the drawings. Elements or parts in the drawings are not necessarily drawn to scale.

[0014] Figure 1 This is a structural schematic diagram of a 96-well plate experimental device of the present invention;

[0015] Figure 2 This is another structural schematic diagram of the 96-well plate experimental device of the present invention;

[0016] In the accompanying drawings, 1 is the bottom plate, 2 is the lower plate, 3 is the support rod, 4 is the bottom plate hole, 5 is the SPE column, 6 is the upper plate, 7 is the top plate hole, 8 is the gripping block, and 9 is the gap. DETAILED DESCRIPTION

[0017] The following embodiments of the technical solution of the present invention are described in detail with reference to the accompanying drawings. The following embodiments are only used to more clearly illustrate the technical solution of the present invention and are therefore only examples and are not intended to limit the scope of protection of the present invention.

[0018] It should be noted that, unless otherwise specified, the technical terms or scientific terms used in this application should have the common meanings understood by those skilled in the art in the field of this utility model.

[0019] Example:

[0020] like Figure 1 、 Figure 2As shown, the 96-well plate experimental device of the present invention includes a bottom plate 1 and a top plate, between which support rods 3 are respectively located at the four corners, 96 bottom plate holes 4 are evenly spaced on the bottom plate 1, and 96 top plate holes 7 are provided on the top plate, each top plate hole 7 vertically corresponding to a bottom plate hole 4; and an SPE column 5 is also included, the upper end of the SPE column 5 cooperates with the top plate hole 7, and the lower end cooperates with the bottom plate hole 4. The 96-well plate experimental device of the present invention, through the coordination of the bottom plate 1, the top plate, the support rods 3, the bottom plate holes 4, the top plate holes 7 and the SPE column 5, does not require mold making compared to the 96-well plate experimental device with an integrated mold in the prior art, which can reduce costs; a corresponding number of SPE columns 5 can be used according to the actual experimental needs, reducing the waste of hole fillers; there is no thick plastic plate to block the line of sight, and it is convenient to observe the liquid level passing through.

[0021] As preferably, the top plate includes a lower plate 2 and an upper plate 6 detachably connected to the top surface of the lower plate 2, and the bottom surface of the lower plate 2 is connected to the support rod 3; the top plate hole 7 runs through the upper plate 6 and the lower plate 2, and the top of the SPE column 5 is provided with a clamping portion whose effective diameter is greater than the effective diameter of the top plate hole 7. After such design, after the SPE column 5 is inserted from the top plate hole 7, the clamping portion at the top is stuck in the top outside of the top plate hole 7. When removing the SPE column 5, the SPE column 5 can be completely removed by removing the upper plate 6, which greatly improves efficiency. It should be noted that the upper plate 6 and the lower plate 2 can be connected by a pin or a screw.

[0022] Preferably, downwardly inclined slopes are provided on both sides of the top surface of the lower plate 2, and a gap 9 is formed between the slope and the upper plate 6 for convenient removal of the upper plate 6. After such a design, the experimenter can insert his fingers into the gap 9 and conveniently remove the upper plate 6.

[0023] Preferably, gripping blocks 8 are provided on both sides of the top surface of the base plate 1. This design allows the experimenter to easily grasp the gripping blocks 8 and move the entire device. Furthermore, preferably, the gripping blocks 8 are provided with anti-slip patterns to increase friction and prevent slipping.

[0024] As an example, the bottom end of the support rod 3 is threadedly matched with the bottom plate 1, and the top end can be connected to the lower plate 2 by screws or pins. It should be noted that the bottom end of the support rod 3 can also be plugged into the bottom plate.

[0025] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the above embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the above embodiments, or make equivalent replacements for some or all of the technical features therein. These modifications or replacements do not deviate the essence of the corresponding technical solutions from the scope of the technical solutions of the embodiments of the present invention, and they should all be included in the scope of the claims and description of the present invention.

Claims

1. 96-well plate experimental device, characterized by: The invention comprises a bottom plate (1) and a top plate, wherein support rods (3) are respectively arranged at four corners between the bottom plate (1) and the top plate, 96 bottom plate holes (4) are evenly spaced on the bottom plate (1), and 96 top plate holes (7) are arranged on the top plate, and each top plate hole (7) vertically corresponds to a bottom plate hole (4); and an SPE column (5) is also included, wherein the upper end of the SPE column (5) is matched with the top plate hole (7), and the lower end is matched with the bottom plate hole (4).

2. The 96-well plate experimental device according to claim 1, characterized in that: The top plate comprises a lower plate (2) and an upper plate (6) detachably connected to the top surface of the lower plate (2), and the bottom surface of the lower plate (2) is connected to the support rod (3); the top plate hole (7) passes through the upper plate (6) and the lower plate (2), and the top of the SPE column (5) is provided with a clamping portion with an effective diameter larger than the effective diameter of the top plate hole (7).

3. The 96-well plate experimental device according to claim 2, characterized in that: Downward-sloping slopes are provided on both sides of the top surface of the lower plate (2), and a gap (9) is formed between the slope and the upper plate (6) for convenient removal of the upper plate (6).

4. The 96-well plate experimental device according to claim 3, characterized in that: Gripping blocks (8) are provided on both sides of the top surface of the bottom plate (1).

5. The 96-well plate experimental device according to claim 4, characterized in that: Anti-slip lines are provided on the gripping block (8).

6. The 96-well plate experimental device according to claim 5, characterized in that: The bottom end of the support rod (3) is threadedly engaged with the bottom plate (1).