Separation tube for cell separation and extraction

Abstract

The utility model relates to the technical field of separation tubes, and discloses a cell separation and extraction separation tube which comprises a separation tube body, a supporting mechanism is arranged on the periphery of the separation tube body, a sealing mechanism is arranged at the top of the separation tube body, the supporting mechanism comprises a fixing sleeve, the fixing sleeve is fixedly connected to the periphery of the separation tube body, and the sealing mechanism is arranged on the fixing sleeve. The left side of the fixing sleeve is fixedly connected with a connecting frame, the inner top of the connecting frame is fixedly connected with a telescopic rod, and the periphery of the telescopic rod is sleeved with a first spring. Under the action of a fixing sleeve, a connecting frame, a connecting column, a fixing block and a supporting sleeve, the separating pipe body can be stably placed on a table top and is placed in a vertical state, the stability and safety of the separating pipe body are guaranteed, and meanwhile in the using process, the connecting frame can be held by hand to use the separating pipe body.

Description

Technical Field

[0001] The utility model relates to the technical field of separation tubes, in particular to a cell separation and extraction separation tube. Background Art

[0002] Cell separation and extraction is a laboratory technique used to isolate cells with specific characteristics from a complex mixture of cells. This technology has important applications in basic biological research, clinical diagnosis, drug development, and cell therapy. Separation tubes are laboratory instruments commonly used to separate liquid and solid samples. They are required for cell separation and extraction. Existing separation tubes have a raised bottom, which often requires a tube rack when placed on a bench or desktop. This makes them inconvenient to place on a desktop, resulting in poor performance.

[0003] According to the description of a cell separation tube for rapid separation and extraction of PBMCs published on the patent website (authorization publication number: CN216808795U), the cell separation tube for rapid separation and extraction of PBMCs includes a "separation tube body, a separation screen plate, a liquid injection hole at the bottom of the screen plate", etc., to carry out the extraction work.

[0004] In view of the above description, the applicant believes that the following problems exist:

[0005] The cell separation tube for rapid separation and extraction of PBMC utilizes a separation tube body, a separation sieve plate, and a liquid injection hole at the bottom of the sieve plate to perform the extraction work. During use, when the separation tube needs to be placed on a laboratory bench or desktop, it usually needs to be placed with a tube rack, which is inconvenient to place on the desktop, resulting in poor use effect and cannot be placed directly on the desktop. Therefore, there is a need to improve this separation tube. Utility Model Content

[0006] The purpose of the utility model is to provide a cell separation and extraction separation tube to solve the problems raised in the above background technology.

[0007] To achieve the above-mentioned object, the present invention provides the following technical solutions: a cell separation and extraction separation tube, comprising a separation tube body, a support mechanism being provided on the periphery of the separation tube body, and a sealing mechanism being provided on the top of the separation tube body;

[0008] The supporting mechanism includes a fixing sleeve, which is fixedly connected to the periphery of the separation tube body, a connecting frame fixedly connected to the left side of the fixing sleeve, a telescopic rod fixedly connected to the top of the connecting frame, a first spring sleeved on the periphery of the telescopic rod, a connecting column fixedly connected to the bottom of the telescopic rod, a connecting column slidably connected to the inside of the connecting frame, a fixing block fixedly connected to the bottom of the connecting column, a supporting sleeve fixedly connected to the right side of the fixing block, a supporting sleeve slidably connected to the periphery of the separation tube body, a card block inserted into the inside of the connecting frame, a first pull ring fixedly connected to the front side of the card block, and a rear side of the card block inserted into the inside of the connecting column.

[0009] Preferably, the top of the first spring is fixedly connected to the top of the connecting frame, and the bottom of the first spring is fixedly connected to the top of the connecting column, so that the first telescopic rod and the connecting column are in a stable state inside the connecting frame under the action of the first spring.

[0010] Preferably, a sliding groove is provided inside the connecting frame, and the connecting column is slidably connected to the sliding groove, so that the connecting column can move more stably inside the connecting frame under the action of the sliding groove.

[0011] Preferably, the support sleeve is in the shape of a circular ring, and a non-slip pad is provided at the bottom of the support sleeve, so that the separation tube body can be placed in a stable state on a laboratory bench or a desktop under the action of the support sleeve.

[0012] Preferably, the sealing mechanism includes a sealing cover, which is slidably connected to the top of the separation tube body, a fixed frame is fixedly connected to the right side of the sealing cover, a fixed rod is fixedly connected inside the fixed frame, a moving block is slidably connected to the periphery of the fixed rod, a second pull ring is fixedly connected to the right side of the moving block, a limiting rod is fixedly connected to the left side of the moving block, the limiting rod is slidably connected to the inside of the sealing cover, the left side of the limiting rod is inserted into the inside of the separation tube body, and a second spring is sleeved on the periphery of the fixed rod.

[0013] Preferably, the left side of the second spring is fixedly connected to the right side of the moving block, and the right side of the second spring is fixedly connected to the right side of the fixed frame, so that the moving block and the limiting rod can be in a stable state under the action of the second spring.

[0014] Preferably, a slot is provided inside the separation tube body, the left side of the limiting rod is inserted into the slot, and the top of the sealing cover contacts the top of the separation tube body, so that the sealing cover can be in a stable state at the top of the separation tube body under the action of the limiting rod.

[0015] Compared with the prior art, the present invention provides a cell separation and extraction separation tube with the following beneficial effects:

[0016] The cell separation and extraction separation tube can be placed on the desktop through the support mechanism when the separation tube needs to be placed on the desktop during use. Under the action of the fixing sleeve, the connecting frame, the connecting column, the fixing block and the supporting sleeve, the separation tube body can be stably placed on the desktop, and the separation tube body is placed in a vertical state to ensure the stability and safety of the separation tube body. At the same time, during use, the connecting frame can be held by hand to use the separation tube body, thereby preventing the separation tube body from slipping out of the hand during use. When the separation tube body needs to be placed vertically on the desktop, the clamping block is removed and the supporting sleeve is pulled downward so that the fixing block drives the connecting column to move downward inside the connecting frame. During the movement, the connecting column drives the telescopic rod and the first spring to deform. When the bottom of the support sleeve contacts the ground, the clamping block can be inserted into the connecting frame and the connecting column, and the connecting column can be kept in a stable state inside the connecting frame under the action of the clamping block, thereby ensuring the stability of the support sleeve. At the same time, when the support sleeve contacts the desktop, the separation tube body can be stably placed on the desktop, thereby improving the use effect.

[0017] The cell separation and extraction separation tube can achieve a sealing effect on the top of the separation tube body under the action of the sealing cover through the provided sealing mechanism, thereby ensuring the sealing of the separation tube body during use and ensuring that the sample will not leak out during centrifugation or other experimental processes. At the same time, the sealing cover can be sealed under the action of the limit rod, the movable block, the second pull ring and the second spring, so that the sealing cover is in a stable state on the top of the separation tube body, and the sealing cover is easy to install and disassemble, and the thread slippage caused by fixing the sealing cover in a spiral manner can be avoided, thereby improving the use effect. When the sealing cover needs to be removed, the second pull ring is pulled to the right, so that the movable block drives the limit rod to move to the right, and the movable block slides on the periphery of the fixed rod to squeeze the second spring, so that the limit on the sealing cover can be released and the sealing cover can be removed. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without inventive work.

[0019] Figure 1 This is a schematic diagram of the three-dimensional structure of the utility model;

[0020] Figure 2 This is a schematic diagram of the cross-sectional structure of the utility model;

[0021] Figure 3 Schematic diagram of the supporting mechanism structure;

[0022] Figure 4 Schematic diagram of the internal structure of the connecting frame;

[0023] Figure 5 It is a schematic diagram of the cross-sectional structure of the connecting frame;

[0024] Figure 6 Schematic diagram of the sealing mechanism structure;

[0025] Figure 7 for Figure 6 Enlarged structural diagram at point A in the middle.

[0026] In the figure: 1. separation tube body; 2. support mechanism; 3. sealing mechanism; 21. fixing sleeve; 22. connecting frame; 23. connecting column; 24. fixing block; 25. support sleeve; 26. telescopic rod; 27. first spring; 28. clamping block; 29. ​​first pull ring; 31. sealing cover; 32. fixing frame; 33. second pull ring; 34. moving block; 35. limiting rod; 36. second spring; 37. fixing rod. DETAILED DESCRIPTION

[0027] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0028] In this utility model, unless otherwise specified or limited, the terms "installed," "connected," "connect," "fixed," etc. should be understood in a broad sense. For example, they can refer to fixed connection, detachable connection, or integration; mechanical connection, electrical connection; direct connection, indirect connection through an intermediate medium, internal communication between two components, or interaction between two components. Those skilled in the art will understand the specific meanings of the above terms in this utility model based on specific circumstances.

[0029] The utility model provides the following technical solutions: Example 1

[0030] See also Figure 1-7 The utility model provides a technical solution: a cell separation and extraction separation tube, comprising a separation tube body 1, a support mechanism 2 is provided on the periphery of the separation tube body 1, and a sealing mechanism 3 is provided on the top of the separation tube body 1;

[0031] The supporting mechanism 2 includes a fixed sleeve 21, which is fixedly connected to the outer periphery of the separation tube body 1. A connecting frame 22 is fixedly connected to the left side of the fixed sleeve 21. A telescopic rod 26 is fixedly connected to the top of the connecting frame 22. A first spring 27 is sleeved on the outer periphery of the telescopic rod 26. A connecting column 23 is fixedly connected to the bottom of the telescopic rod 26. The connecting column 23 is slidably connected to the inside of the connecting frame 22. A fixed block 24 is fixedly connected to the bottom of the connecting column 23. A supporting sleeve 25 is fixedly connected to the right side of the fixed block 24. The supporting sleeve 25 is slidably connected to the outer periphery of the separation tube body 1. A card block 28 is inserted into the inside of the connecting frame 22. The front side of the card block 28 is fixedly connected to the first pull ring 29, and the rear side of the card block 28 is inserted into the inside of the connecting column 23.

[0032] The top of the first spring 27 is fixedly connected to the top of the connecting frame 22, and the bottom of the first spring 27 is fixedly connected to the top of the connecting column 23, so that under the action of the first spring 27, the first telescopic rod 26 and the connecting column 23 are in a stable state inside the connecting frame 22. A slide groove is provided inside the connecting frame 22, and the connecting column 23 is slidably connected in the slide groove, so that under the action of the slide groove, the connecting column 23 can move more stably inside the connecting frame 22. The support sleeve 25 is annular, and an anti-slip pad is provided at the bottom of the support sleeve 25, so that under the action of the support sleeve 25, the separation tube body 1 can be placed in a stable state when placed on a laboratory bench or a desktop. Example 2

[0033] See also Figure 1-7 , and on the basis of embodiment 1, the sealing mechanism 3 is further obtained to include a sealing cover 31, the sealing cover 31 is slidably connected to the top of the separation tube body 1, the right side of the sealing cover 31 is fixedly connected to a fixed frame 32, the fixed frame 32 is fixedly connected to a fixed rod 37, the outer periphery of the fixed rod 37 is slidably connected to a moving block 34, the right side of the moving block 34 is fixedly connected to a second pull ring 33, the left side of the moving block 34 is fixedly connected to a limiting rod 35, the limiting rod 35 is slidably connected to the inside of the sealing cover 31, the left side of the limiting rod 35 is inserted into the inside of the separation tube body 1, and fixed A second spring 36 is sleeved on the outer periphery of the rod 37. The left side of the second spring 36 is fixedly connected to the right side of the moving block 34, and the right side of the second spring 36 is fixedly connected to the right side of the fixed frame 32, so that under the action of the second spring 36, the moving block 34 and the limiting rod 35 can be in a stable state. A slot is provided inside the separation tube body 1, and the left side of the limiting rod 35 is inserted into the slot. The top inside the sealing cover 31 contacts the top of the separation tube body 1, so that under the action of the limiting rod 35, the sealing cover 31 can be in a stable state at the top of the separation tube body 1.

[0034] When the sealing cap 31 is in the closed position, the sealing cap 31 is in the closed position, and the sealing cap 31 is in the closed position. The clamping block 28 is in a stable state and plays a sealing role on the top of the separation tube body 1. When the separation tube body 1 needs to be placed on a laboratory bench or desktop during use, the clamping block 28 is removed and the support sleeve 25 is pulled downward so that the fixing block 24 drives the connecting column 23 to move downward inside the connecting frame 22. During the movement, the connecting column 23 will drive the telescopic rod 26 and the first spring 27 to deform. When the bottom of the support sleeve 25 contacts the ground, the clamping block 28 can be inserted into the connecting frame 22 and the connecting column 23. Under the action of the clamping block 28, the connecting column 23 can be in a stable state inside the connecting frame 22, ensuring the stability of the support sleeve 25. At the same time, when the support sleeve 25 contacts the desktop, the separation tube body 1 can be stably placed on the desktop, thereby improving the use effect and ensuring the stability of the separation tube body 1.

[0035] It should be noted that, in this document, relational terms such as first and second, etc., are used only to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the terms "comprises," "comprising," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or device comprising a series of elements includes not only those elements, but also other elements not explicitly listed, or elements inherent to such process, method, article, or device. In the absence of further limitations, an element defined by the phrase "comprising a..." does not exclude the presence of additional identical elements in the process, method, article, or device comprising the element.

Claims

1. A cell separation and extraction separation tube, comprising a separation tube body (1), characterized in that: A support mechanism (2) is provided on the periphery of the separation tube body (1), and a sealing mechanism (3) is provided on the top of the separation tube body (1); The support mechanism (2) comprises a fixed sleeve (21), the fixed sleeve (21) is fixedly connected to the periphery of the separation tube body (1), the left side of the fixed sleeve (21) is fixedly connected to a connecting frame (22), the top of the connecting frame (22) is fixedly connected to a telescopic rod (26), the periphery of the telescopic rod (26) is sleeved with a first spring (27), the bottom of the telescopic rod (26) is fixedly connected to a connecting column (23), the connecting column (23) is slidably connected to the inside of the connecting frame (22), the bottom of the connecting column (23) is fixedly connected to a fixed block (24), the right side of the fixed block (24) is fixedly connected to a support sleeve (25), the support sleeve (25) is slidably connected to the periphery of the separation tube body (1), a clamping block (28) is inserted into the inside of the connecting frame (22), the front side of the clamping block (28) is fixedly connected to a first pull ring (29), and the rear side of the clamping block (28) is inserted into the inside of the connecting column (23).

2. A cell separation and extraction separation tube according to claim 1, characterized in that: The top of the first spring (27) is fixedly connected to the top of the connecting frame (22), and the bottom of the first spring (27) is fixedly connected to the top of the connecting column (23).

3. The cell separation and extraction separation tube according to claim 1, characterized in that: A sliding groove is provided inside the connecting frame (22), and the connecting column (23) is slidably connected in the sliding groove.

4. The cell separation and extraction separation tube according to claim 1, characterized in that: The support sleeve (25) is annular in shape, and a non-slip pad is provided at the bottom of the support sleeve (25).

5. The cell separation and extraction separation tube according to claim 1, characterized in that: The sealing mechanism (3) comprises a sealing cover (31), the sealing cover (31) is slidably connected to the top of the separation tube body (1), the right side of the sealing cover (31) is fixedly connected to a fixing frame (32), the fixing frame (32) is fixedly connected to a fixing rod (37), the outer periphery of the fixing rod (37) is slidably connected to a moving block (34), the right side of the moving block (34) is fixedly connected to a second pull ring (33), the left side of the moving block (34) is fixedly connected to a limiting rod (35), the limiting rod (35) is slidably connected to the inside of the sealing cover (31), the left side of the limiting rod (35) is inserted into the inside of the separation tube body (1), and the outer periphery of the fixing rod (37) is sleeved with a second spring (36).

6. The cell separation and extraction separation tube according to claim 5, characterized in that: The left side of the second spring (36) is fixedly connected to the right side of the moving block (34), and the right side of the second spring (36) is fixedly connected to the right side inside the fixed frame (32).

7. The cell separation and extraction separation tube according to claim 5, characterized in that: A slot is provided inside the separation tube body (1), the left side of the limiting rod (35) is inserted into the slot, and the top of the sealing cover (31) contacts the top of the separation tube body (1).

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