Automatic flaking device

Abstract

The utility model discloses an automatic slide making device which comprises an operation table, a supporting mechanism, a slide supply unit, a staining fluid injection unit, a cover glass processing unit and a knocking execution unit, the supporting mechanism comprises a rack, a first operation arm and a second operation arm, and the rack is rotatably and movably connected to the operation table; a first operation arm and a second operation arm are arranged on the two opposite sides of the rack respectively, the first end of the first operation arm is connected to the rack, the second end of the first operation arm is provided with a staining fluid injection unit and a cover glass processing unit, the first end of the second operation arm is connected to the rack, and the second end of the second operation arm is provided with a knocking execution unit. The knocking execution unit comprises a knocking piece, a telescopic driving piece and a control unit used for controlling the telescopic speed of the telescopic driving piece, the telescopic driving piece is arranged at the second end of the second operation arm, the driving end of the telescopic driving piece is connected with the knocking piece, and the telescopic driving piece can drive the knocking piece to knock the cover glass located on the piece supply unit.

Description

Technical Field

[0001] The utility model relates to the technical field of cell and tissue slice making, in particular to an automatic slice making device. Background Art

[0002] Slide preparation technology has a wide range of applications in plant and animal research, especially in the fields of plant tissue structure observation and chromosome karyotype analysis. The slide preparation process usually involves multiple steps, including staining, coverslipping, and subsequent tapping operations. Traditional slide preparation methods mostly rely on manual operations, which have many shortcomings, such as uneven tissue dispersion, insufficient pressure, or excessive pressure causing the coverslip to break. These problems directly affect the quality of the slide preparation and the reliability of the experimental results. Therefore, it is particularly important to develop a device that can automatically complete the slide preparation process. Utility Model Content

[0003] The purpose of this utility model is to provide an automatic film-making device to solve the problems raised in the above background technology.

[0004] In order to achieve the above-mentioned object, the present disclosure provides an automatic slide making device, comprising an operating table, a supporting mechanism, a slide supply unit, a staining solution injection unit, a cover glass processing unit, and a knocking execution unit;

[0005] The support mechanism includes a frame, a first operating arm and a second operating arm, the frame is rotatably and movably connected to the operating table, the first operating arm and the second operating arm are respectively provided on opposite sides of the frame, the first end of the first operating arm is connected to the frame, the second end of the first operating arm is provided with the staining solution injection unit and the coverslip processing unit, the first end of the second operating arm is connected to the frame, and the second end of the second operating arm is provided with the knocking execution unit;

[0006] The slide supply unit is arranged on the operating table and is used for carrying slides and cover slips;

[0007] The dyeing solution injection unit is used to inject dyeing solution into the tissue cells located on the slide;

[0008] The cover glass processing unit is used to store the cover glass and place the cover glass on the slide;

[0009] The knocking execution unit includes a knocking member, a telescopic driving member and a control unit for controlling the telescopic speed of the telescopic driving member. The second end of the second operating arm is provided with the telescopic driving member, and the driving end of the telescopic driving member is connected to the knocking member. The telescopic driving member can drive the knocking member to knock the coverslip located on the film supply unit to promote the uniform distribution of tissue cells on the coverslip.

[0010] Optionally, the knocking member includes a knocking plate and two knocking parts arranged at the bottom of the knocking plate;

[0011] The two striking parts are arranged at intervals on the same level;

[0012] Two grooves are formed on the bottom of the knocking plate, and one knocking part is correspondingly arranged in each of the grooves;

[0013] A telescopic rod and a spring extending in a direction perpendicular to the thickness of the groove are provided in each of the grooves. The spring is sleeved on the telescopic rod. Both ends of the telescopic rod are respectively connected to the knocking part and the bottom of the groove.

[0014] Optionally, the automatic slide making device further comprises a connecting rod, the cover glass processing unit comprises a first driving member, a fixed clamper, and a movable clamper, and the staining liquid injection unit comprises a liquid storage tank, an injection hose, and a injection pump;

[0015] The fixed clamp and the movable clamp are arranged opposite to each other on the bottom surface of the second end of the first operating arm, the driving end of the first driving member is connected to the side of the movable clamp facing away from the fixed clamp, and the first driving member is configured to drive the movable clamp to move in a direction close to or away from the fixed clamp, and the movable clamp has a first position close to the fixed clamp and a second position away from the fixed clamp;

[0016] The first operating arm is formed with a receiving cavity for receiving the liquid storage tank and the injection pump, and the first end of the injection hose passes through the first operating arm and is connected to the liquid storage tank through the injection pump;

[0017] One end of the connecting rod is connected to a side of the movable clamp facing away from the fixed clamp, and the other end of the connecting rod is connected to the second end of the injection hose;

[0018] wherein, in the first position, the second end of the injection hose is directed toward the slide on the slide supply unit. Optionally, the first operating arm is configured to adjust the horizontal and vertical positions of the cover glass processing unit and the staining solution injection unit, and the second operating arm is configured to adjust the horizontal and vertical positions of the knocking execution unit.

[0019] Optionally, the first operating arm includes a first connecting member, a first joint, and a first rocker arm, wherein a first end of the first connecting member is connected to a side wall of the frame, a second end of the first connecting member is connected to the first joint, a first end of the first rocker arm is hinged to the first joint, and a second end of the first rocker arm is provided with the coverslip processing unit and the staining solution injection unit;

[0020] The second operating arm includes a second connecting member, a second joint, a second rocker arm, a third joint, and a third rocker arm. The first end of the second connecting member is connected to the side wall of the frame, the second end of the second connecting member is connected to the second joint, the first end of the second rocker arm is hinged to the second joint, the third joint is connected to the second end of the second rocker arm, the first end of the third rocker arm is hinged to the third joint, and the second end of the third rocker arm is provided with the knocking execution unit. Optionally, the first operating arm also includes a second driving member, and the second operating arm also includes a third driving member and the fourth driving member.

[0021] The second driving member is in transmission connection with the first rocker arm to drive the first rocker arm to rotate relative to the frame and change the angle between the first rocker arm and the frame;

[0022] The third driving member is in transmission connection with the second rocker arm to drive the second rocker arm to rotate relative to the frame and change the angle between the second rocker arm and the frame;

[0023] The fourth driving member is in transmission connection with the third rocker arm to drive the third rocker arm to rotate relative to the second rocker arm and change the angle between the third rocker arm and the second rocker arm.

[0024] Optionally, the film supply unit includes a loading plate, two limiting members and a telescopic mechanism;

[0025] The two limiting members are arranged on the top of the object plate and are respectively located at two opposite corners of the slide;

[0026] The telescopic mechanism includes a driver and a telescopic rod. The driver is located in a groove on the operating table. The telescopic rod is vertically arranged. The bottom of the telescopic rod is transmission-connected to the driver. The driver can drive the telescopic rod to extend or shorten. The loading plate is connected to the top of the telescopic rod.

[0027] Optionally, the frame includes a main frame, a base, a fifth driving member, a mounting seat and a driving mechanism;

[0028] The fifth driving member is located in the main frame, and the fifth driving member is configured to drive the main frame to be rotatably connected to the base;

[0029] The top of the operating table is provided with a slide groove extending to the bottom thereof, and the base is slidably connected to the slide groove;

[0030] The driving mechanism includes a sixth driving member and a transmission assembly, and the output shaft of the driving member is connected to the mounting seat through the transmission assembly, so that the mounting seat can move on the workbench along the length direction of the slide groove.

[0031] Optionally, the automatic film-making device further comprises a first mounting plate and a second mounting plate, and the transmission assembly comprises a screw, a moving block, two mounting blocks, a driving sprocket, a driven sprocket and a chain;

[0032] The first mounting plate is mounted on the bottom of the opening close to the chute, the two mounting blocks are both located below the bottom of the operating table, one of the two mounting blocks is disposed on the first mounting plate, and the other of the two mounting blocks is disposed on the bottom of the operating table;

[0033] The second mounting plate is arranged at the bottom of the operating table, the sixth driving member is mounted on the second mounting plate, and the driving end of the sixth driving member is sleeved with the driving sprocket;

[0034] The two ends of the screw rod are respectively passed through the two mounting blocks and rotatably connected to the two mounting blocks. The driven sprocket is sleeved on the outward end of the screw rod. The chain is rotatably sleeved between the driving sprocket and the driven sprocket.

[0035] The moving block is installed at the bottom of the mounting seat, the moving block is located between two mounting blocks, and the moving block is movably connected to the screw rod.

[0036] Optionally, the automatic film-making device further includes a control device;

[0037] The control device is arranged on the frame, and the control device is electrically connected to the supporting mechanism, the film supply unit, the staining liquid injection unit, the cover glass processing unit and the knocking execution unit.

[0038] According to the above technical solution, by setting up a support mechanism, since the frame of the support mechanism can be rotated and moved on the operating table, a first operating arm and a second operating arm are respectively installed on both sides of the frame, the end of the first operating arm can be equipped with a dye injection unit and a coverslip processing unit, and the end of the second operating arm can be equipped with a knocking execution unit. In this way, the following control device can be used to control the rotation of the frame according to the sequence of the production operation, thereby controlling the dye injection unit and the coverslip processing unit of the first operating arm and the knocking execution unit of the second operating arm to sequentially stain the cell tissue on the slide supply unit (slide) and place the coverslip. The work of placing it on the slide and knocking the coverslip, wherein, by setting a knocking execution unit, the knocking action helps the tissue cells to be evenly distributed on the coverslip, wherein the knocking piece can be used as a component for executing the knocking action, the telescopic driving piece can be used as a component for driving the knocking piece to perform the knocking action, and the control unit can control the telescopic speed of the telescopic driving piece, thereby controlling the intensity and frequency of the knocking. In this way, not only can it be prevented that the knocking is too strong to cause cell rupture or morphological changes, and the knocking is too weak to achieve the uniform distribution of cells, but it can also prevent excessive knocking from causing damage to the equipment (such as the coverslip). Such a design can make the preparation process highly automated. On the one hand, it can accurately control parameters such as the injection volume of the staining solution, the position of the coverslip and the knocking intensity, thereby ensuring the high controllability of the preparation process and helping to maintain the quality and consistency of the sample; on the other hand, it can reduce human errors and help improve preparation efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] Figure 1 A three-dimensional view of an automatic film-making device provided by an exemplary embodiment of the present disclosure from a first perspective, wherein a first operating arm and a second operating arm are located on both sides of a slide slot;

[0040] Figure 2 A perspective view of an automatic film-making device provided by an exemplary embodiment of the present disclosure from a second perspective, wherein the first operating arm is located above the film supply unit;

[0041] Figure 3 for Figure 2 A magnified schematic diagram of part A in FIG;

[0042] Figure 4 A perspective view of an automatic film-making device provided in accordance with an exemplary embodiment of the present disclosure, wherein the second operating arm is located above the film supply unit;

[0043] Figure 5 for Figure 4 A magnified schematic diagram of part B in FIG.

[0044] Figure 6 A cross-sectional view of a knocking member of an automatic film-making device provided in accordance with an exemplary embodiment of the present disclosure;

[0045] Figure 7 This is a three-dimensional view of an automatic film-making device provided in an exemplary embodiment of the present disclosure from a third perspective, wherein the second operating arm is located above the film supply unit.

[0046] In the figure: 10, operating table; 11, slide; 20, supporting mechanism; 21, frame; 211, main frame; 212, base; 213, mounting seat; 214, driving mechanism; 2141, sixth driving member; 2142, screw; 2143, moving block; 2144, mounting block; 2145, driving sprocket; 2146, driven sprocket; 2147, chain; 22, first operating arm; 221, first connecting member; 222, first joint; 223, first rocker arm; 23, second operating arm; 231, second connecting member; 232, second joint; 233, second rocker arm; 234, third joint Section; 235, third rocker arm; 30, film supply unit; 31, loading plate; 32, limit member; 33, telescopic rod; 40, stain solution injection unit; 41, injection hose; 50, cover glass processing unit; 51, first driving member; 52, fixed clamp; 53, movable clamp; 60, knocking execution unit; 61, knocking member; 611, knocking plate; 612, knocking part; 613, groove; 614, telescopic rod; 615, spring; 62, telescopic driving member; 70, slide; 71, cover glass; 72, connecting rod; 73, first mounting plate; 74, second mounting plate; 80, control device. DETAILED DESCRIPTION

[0047] The following describes the specific embodiments of the present disclosure in detail with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are only used to illustrate and explain the present disclosure and are not intended to limit the present disclosure.

[0048] In the description of the present disclosure, in the present disclosure, unless otherwise specified, "inside" and "outside" refer to the inside and outside of the corresponding component outline. In addition, the terms "first" and "second" are used to distinguish one element from another and have no sequential or importance.

[0049] It should also be noted that, in the description of this disclosure, unless otherwise expressly specified or limited, the terms "disposed," "connected," "connected," and "installed" should be understood broadly. For example, they may refer to fixed connections, detachable connections, or integral connections; they may refer to direct connections, indirect connections via an intermediate medium, or internal connections between two components. Those skilled in the art will understand the specific meanings of these terms in this disclosure based on specific circumstances.

[0050] like Figures 1 to 7As shown, the present disclosure provides an automatic film-making device, including an operating table 10, a supporting mechanism 20, a film supply unit 30, a dyeing liquid injection unit 40, a cover glass processing unit 50, and a knocking execution unit 60. The supporting mechanism 20 includes a frame 21, a first operating arm 22, and a second operating arm 23. The frame 21 is rotatably and movably connected to the operating table 10. The first operating arm 22 and the second operating arm 23 are respectively provided on opposite sides of the frame 21. The first end of the first operating arm 22 is connected to the frame 21, and the second end of the first operating arm 22 is provided with the dyeing liquid injection unit 40 and the cover glass processing unit 50. The first end of the second operating arm 23 is connected to the frame 21, and the second end of the second operating arm 23 is provided with the knocking execution unit 60. 0, the film supply unit 30 is arranged on the operating table 10, and is used to carry the slide 70 and the cover glass 71, the staining liquid injection unit 40 is used to inject staining liquid into the tissue cells located on the slide 70, the cover glass processing unit 50 is used to store the cover glass 71 and place the cover glass 71 on the slide 70, the knocking execution unit 60 includes a knocking member 61, a telescopic driving member 62 and a control unit for controlling the telescopic speed of the telescopic driving member 62, the second end of the second operating arm 23 is provided with a telescopic driving member 62, the driving end of the telescopic driving member 62 is connected to the knocking member 61, and the telescopic driving member 62 can drive the knocking member 61 to knock the cover glass 71 located on the film supply unit 30 to promote the uniform distribution of tissue cells on the cover glass 71.

[0051] According to the above technical solution, the support mechanism 20 is provided. Since the frame 21 of the support mechanism 20 can be rotated and moved on the operating table 10, the first operating arm 22 and the second operating arm 23 are respectively installed on both sides of the frame 21. The end of the first operating arm 22 can be equipped with a dye injection unit 40 and a cover glass processing unit 50, and the end of the second operating arm 23 can be equipped with a knocking execution unit 60. In this way, the frame 21 can be controlled to rotate according to the sequence of the film making operation by using the following control device 80, thereby controlling the dye injection unit 40 and the cover glass processing unit 50 of the first operating arm 22 and the knocking execution unit 60 of the second operating arm 23 to sequentially perform the fine particles on the film supply unit 30 (slide 70). The work of cell tissue staining, placing the coverslip 71 on the slide 70 and knocking the coverslip 71, wherein, by setting the knocking execution unit 60, the knocking action helps the tissue cells to be evenly distributed on the coverslip 71, wherein the knocking member 61 can be used as a component for executing the knocking action, and the telescopic driving member 62 can be used as a component for driving the knocking member 61 to perform the knocking action. The control unit can control the telescopic speed of the telescopic driving member 62, thereby controlling the intensity and frequency of the knocking. In this way, not only can it be prevented that the knocking is too strong to cause cell rupture or morphological changes, and the knocking is too weak to achieve the uniform distribution of cells, but it can also prevent excessive knocking from causing damage to the equipment (such as the coverslip 71). Such a design can make the preparation process highly automated. On the one hand, it can accurately control parameters such as the injection volume of the staining solution, the position of the coverslip 71 and the knocking intensity, thereby ensuring the high controllability of the preparation process and helping to maintain the quality and consistency of the sample; on the other hand, it can reduce human errors and help improve the preparation efficiency.

[0052] As an implementation method, Figure 6 As shown, the knocking member 61 includes a knocking plate 611 and two knocking parts 612 arranged at the bottom of the knocking plate 611. The two knocking parts 612 are arranged at the same horizontal interval. Two grooves 613 are formed at the bottom of the knocking plate 611. A knocking part 612 is correspondingly provided in each groove 613. A telescopic rod 33 and a spring 615 extending in a thickness direction perpendicular to the groove 613 are provided in each groove 613. The spring 615 is sleeved on the telescopic rod 33. The two ends of the telescopic rod 33 are respectively connected to the knocking part 612 and the bottom of the groove 613.

[0053] Among them, the spring 615 is sleeved on the telescopic rod 33, and when the knocking part 612 knocks downward, the spring 615 will be compressed. This compression process absorbs part of the impact energy and plays a buffering role. At the same time, the elasticity of the spring 615 can reduce the vibration during knocking, avoid excessive force transmission caused by hard collisions, and thus protect the cover glass 71 and cell samples from damage. In addition, after the knocking is completed, the spring 615 will push the knocking part 612 back to its initial position. This automatic reset mechanism can ensure the consistency and repeatability of the knocking action. Specifically, when the knocking execution unit 60 is started, the first telescopic drive member 62 drives the knocking member 61 to move downward. When the knocking part 612 contacts the cover glass 71, the telescopic rod 33 begins to move downward, and the spring 615 is compressed, absorbing part of the impact force. After the knocking is completed, the telescopic drive member 62 retracts, and the elastic force of the spring 615 pushes the knocking part 612 back to its original position, completing a knocking cycle.

[0054] Since the knocking force of the two knocking parts 612 acts synchronously on the opposite sides of the cover glass 71, this arrangement can disperse the knocking force more evenly, thereby promoting a more even distribution of tissue cells on the cover glass 71, helping the cells to form a more uniform film on the cover glass 71, and preventing the cells from being too dense or uneven at a certain point.

[0055] In order to improve the buffering effect, optionally, the knocking part 612 can be rubber, silicone, or sponge, and the present disclosure does not limit this.

[0056] As an implementation method, Figure 2 and Figure 3 As shown, the automatic film making device also includes a connecting rod 72, the cover glass processing unit 50 includes a first driving member 51, a fixed clamp 52, and a movable clamp 53, the dye injection unit 40 includes a liquid storage tank, an injection hose 41 and an injection pump, the fixed clamp 52 and the movable clamp 53 are relatively arranged on the bottom surface of the second end of the first operating arm 22, the driving end of the first driving member 51 is connected to the side of the movable clamp 53 away from the fixed clamp 52, and the first driving member 51 is configured to drive the movable clamp 53 to move in a direction close to or away from the fixed clamp 52 The movable clamper 53 has a first position close to the fixed clamper 52 and a second position away from the fixed clamper 52. A accommodating cavity for accommodating a liquid reservoir and an injection pump is formed on the first operating arm 22. The first end of the injection hose 41 passes through the first operating arm 22 and is connected to the liquid reservoir through the injection pump. One end of the connecting rod 72 is connected to the side of the movable clamper 53 away from the fixed clamper 52, and the other end of the connecting rod 72 is connected to the second end of the injection hose 41, wherein, in the first position, the second end of the injection hose 41 faces the glass slide 70 located on the slide supply unit 30.

[0057] The fixed clamp 52 and the movable clamp 53 can be used in conjunction to clamp the cover glass 71. Driven by the first driving member 51, the movable clamp 53 can move between a first position close to the fixed clamp 52 and a second position away from the fixed clamp 52. In other words, when the movable clamp 53 moves to the first position, the fixed clamp 52 and the movable clamp 53 jointly clamp the cover glass 71; when the movable clamp 53 moves to the second position, the cover glass 71 is released. The liquid reservoir is used to store the staining solution.

[0058] The injection hose 41 connects the liquid storage tank and the injection pump to transmit the dyeing liquid.

[0059] Among them, the injection pump can control the delivery volume and speed of the dyeing solution.

[0060] One end of the connecting rod 72 is connected to the movable clamp 53, and the other end is connected to the injection hose 41. This design allows the injection hose 41 to move with the movement of the movable clamp 53. In other words, when the movable clamp 53 is in the first position, the fixed clamp 52 and the movable clamp 53 jointly clamp the cover glass 71. At this time, the control device 80 described below can activate the staining solution injection unit 40, that is, control the injection hose 41 to stain the cell tissue on the slide 70. When the staining work is completed, the following control device 80 can start the coverslip processing unit 50 and stop the staining liquid injection unit 40. Specifically, it controls the first driving member 51 to drive the movable clamp 53 to move to the second position (away from the fixed clamp 52), so that the coverslip 71 is released from the clamping of the fixed clamp 52 and the movable clamp 53 and can accurately fall on the slide 70 under the action of gravity. At the same time, according to the movement of the movable clamp 53, the outlet end of the injection hose 41 can be driven away from the slide 70 through the connecting rod 72, thereby avoiding the injection hose 41 affecting the placement of the coverslip 71.

[0061] In order to enable the knocking execution unit 60, the cover glass processing unit 50 and the dye injection unit 40 to accurately align with the target position on the film supply unit 30, optionally, as shown in FIG. Figures 1 to 4 As shown, the first operating arm 22 is configured to adjust the horizontal and vertical positions of the coverslip handling unit 50 and the staining solution injection unit 40, and the second operating arm 23 is configured to adjust the horizontal and vertical positions of the tapping execution unit 60. This multi-directional adjustment ensures that the staining solution is accurately injected into the tissue cells and that the coverslip 71 is placed stably to avoid bubbles and wrinkles.

[0062] Optionally, by adjusting the angle between the first operating arm 22 and the frame 21, the fixed clamper 52 and the movable clamper 53 can clamp the cover glass 71 at an inclined angle. In this way, when the cover glass 71 is placed on the slide glass 70, one end of the cover glass 71 can first contact the slide glass 70 and then gradually flatten to a horizontal position, so that the cover glass 71 covers the tissue of the slide glass 70, thereby reducing the generation of bubbles.

[0063] Optionally, the first driving member 51 may be a hydraulic drive or an electric drive.

[0064] In order to achieve the purpose of adjusting the positions of the knocking execution unit 60, the cover glass processing unit 50 and the dye injection unit 40 in the horizontal direction and the vertical direction, as an embodiment, Figure 1 As shown, the first operating arm 22 includes a first connecting member 221, a first joint 222 and a first rocker arm 223, the first end of the first connecting member 221 is connected to the side wall of the frame 21, the second end of the first connecting member 221 is connected to the first joint 222, the first end of the first rocker arm 223 is hinged to the first joint 222, and the second end of the first rocker arm 223 is provided with a coverslip processing unit 50 and a dye injection unit 40, the second operating arm 23 includes a second connecting member 231, a second joint 232, a second rocker arm 233, a third joint 234 and a third rocker arm 235, the first end of the second connecting member 231 is connected to the side wall of the frame 21, the second end of the second connecting member 231 is connected to the second joint 232, the first end of the second rocker arm 233 is hinged to the second joint 232, the third joint 234 is connected to the second end of the second rocker arm 233, the first end of the third rocker arm 235 is hinged to the third joint 234, and the second end of the third rocker arm 235 is provided with a knocking execution unit 60.

[0065] The first rocker arm 223 can rotate relative to the frame 21 via the first joint 222, the second rocker arm 233 can rotate relative to the frame 21 via the second joint 232, and the third rocker arm 235 can rotate relative to the second rocker arm 233 via the third joint 234. With this design, the above-mentioned components cooperate with each other to achieve the purpose of adjusting the horizontal and vertical positions of the coverslip processing unit 50 and the dye injection unit 40 on the first rocker arm 223 and the knocking execution unit 60 on the third rocker arm 235. Specifically, by adjusting the position of the first rocker arm 223 via the first joint 222, the dye injection unit 40 and the coverslip processing unit 50 can be accurately aligned with the position of the slide 70, thereby enabling the dye injection unit 40 to accurately align with the tissue cell area on the slide 70 and allowing the coverslip 71 to be placed on the slide 70 at a suitable angle, thereby avoiding the generation of bubbles. The positions of the second rocker arm 233 and the third rocker arm 235 are adjusted by the second joint 232 and the third joint 234, so that the knocking member 61 can accurately and vertically align with the position of the cover glass 71 for knocking. In addition, when film production is not required, the various components on the first operating arm 22 and the second operating arm 23 can be rotated. Specifically, by rotating the first joint 222, the first rocker arm 223 can be folded toward the side wall of the frame 21, and by rotating the second joint 232, the second rocker arm 233 can be folded toward the side wall of the frame 21. By rotating the third joint 234, the third rocker arm 235 can be folded toward the second rocker arm 233, so that the third rocker arm 235 can be completely folded onto the second rocker arm 233. In this way, the first operating arm 22 and the second operating arm 23 can be simultaneously in a folded state, which not only facilitates storage or transportation, but also greatly reduces the occupied space and prevents accidental collision or damage by staff.

[0066] As an implementation method, Figure 1 As shown, the first operating arm 22 also includes a second driving member, and the second operating arm 23 also includes a third driving member and a fourth driving member. The second driving member is connected to the first rocker arm 223 to drive the first rocker arm 223 to rotate relative to the frame 21 and change the angle between the rocker arm 223 and the frame 21. The third driving member is connected to the second rocker arm 233 to drive the second rocker arm 233 to rotate relative to the frame 21 and change the angle between the rocker arm 233 and the frame 21. The fourth driving member is connected to the third rocker arm 235 to drive the third rocker arm 235 to rotate relative to the second rocker arm 233 and change the angle between the rocker arm 233 and the second rocker arm 233.

[0067] Because the second drive member is in transmission connection with the first rocker arm 223, the third drive member is in transmission connection with the second rocker arm 233, and the fourth drive member is in transmission connection with the third rocker arm 235, the first operating arm 22 and the second operating arm 23 can be provided with motion power, motion accuracy, and motion speed, respectively, to achieve multi-degree-of-freedom adjustment, thereby achieving different degrees of deformation of the first operating arm 22 and the second operating arm 23 to meet different production requirements. In some examples, the second drive member, the third drive member, and the fourth drive member can be hydraulic drives or electric drives.

[0068] As an implementation method, Figure 5 As shown, the film supply unit 30 includes a carrier plate 31, two limit members 32 and a telescopic mechanism. The two limit members 32 are arranged on the top of the carrier plate 31 and are respectively located at two opposite corners of the slide 70. The telescopic mechanism includes a driver and a telescopic rod 33. The driver is located in the groove 613 on the operating table 10. The telescopic rod 33 is vertically arranged. The bottom of the telescopic rod 33 is transmission-connected to the driver. The driver can drive the telescopic rod 33 to extend or shorten. The carrier plate 31 is connected to the top of the telescopic rod 33.

[0069] The control device 80 described below can control the height of the carrier plate 31 by controlling the telescopic rod 33 through the control driver, so that the height of the carrier plate 31 can be adjusted during the film making process, thereby better cooperating with the operation of other functional units, such as the coverslip processing unit 50, the staining liquid injection unit 40 and the knocking execution unit 60.

[0070] Among them, two stoppers 32 are set on the top of the sample carrier 31, respectively located at the two opposite corners of the slide 70, for fixing the slide 70, which can prevent the slide 70 from moving during operation, ensuring the stability and accuracy of the preparation process. In order to prevent the cover glass 71 from moving during the knocking process, optionally, as Figure 3 As shown, the height of the limiting member 32 is greater than the thickness of the slide glass 70 .

[0071] As an implementation method, Figure 7As shown, the frame 21 includes a main frame 211, a base 212, a fifth drive member, a mounting seat 213, and a drive mechanism 214. The fifth drive member is located in the main frame 211 and is configured to drive the main frame 211 to be rotatably connected to the base 212. The top of the operating table 10 is provided with a slide 11 extending through the bottom thereof, and the base 212 is slidably connected to the slide 11. The drive mechanism 214 includes a sixth drive member 2141 and a transmission assembly. The output shaft of the drive member is transmission-connected to the mounting seat 213 via the transmission assembly, so that the mounting seat 213 can move on the workbench along the length of the slide 11. Through the combined use of the fifth drive member and the sixth drive member 2141, the main frame 211 can be adjusted in multiple dimensions in the horizontal and vertical directions, ensuring the accurate alignment of each functional unit, reducing manual intervention, and thus improving the degree of automation of the equipment.

[0072] Optionally, the sixth driving member 2141 may be a motor.

[0073] As an implementation method, Figure 7 As shown, the automatic film-making device also includes a first mounting plate 73 and a second mounting plate 74, and the transmission assembly includes a screw 2142, a moving block 2143, two mounting blocks 2144, a driving sprocket 2145, a driven sprocket 2146 and a chain 2147. The first mounting plate 73 is installed at the bottom of the opening near the slide 11, and the two mounting blocks 2144 are both located below the bottom of the operating table 10. One of the two mounting blocks 2144 is set on the first mounting plate 73, and the other of the two mounting blocks 2144 is set at the bottom of the operating table 10. The second mounting plate 74 is set at the bottom of the operating table 10. The driving member 2141 is installed on the second mounting plate 74, and the driving end of the sixth driving member 2141 is sleeved with a driving sprocket 2145. The two ends of the screw rod 2142 are respectively passed through the two mounting blocks 2144 and are rotatably connected to the two mounting blocks 2144. A driven sprocket 2146 is sleeved on the outward end of the screw rod 2142, and the chain 2147 is rotatably sleeved between the driving sprocket 2145 and the driven sprocket 2146. The moving block 2143 is installed at the bottom of the mounting seat 213, and the moving block 2143 is located between the two mounting blocks 2144. The moving block 2143 is movably connected to the screw rod 2142.

[0074] Among them, through the design of the screw 2142 and the moving block 2143, high-precision horizontal movement can be achieved, ensuring that the main frame 211 can accurately reach the desired position.

[0075] The automatic control of the sixth drive member 2141 enables automatic movement of the main frame 211, reducing manual intervention. Specifically, the sixth drive member 2141 controls the driving sprocket 2145, which drives the driven sprocket 2146 to rotate, thereby driving the screw 2142 to rotate, causing the moving block 2143 to move along the screw 2142, driving the mounting seat 213 to move within the slide slot 11, and the main frame 211 to move to the desired position.

[0076] In order to realize the automation of the film-making device, as an embodiment, Figures 1 to 2 As shown, the automatic film-making device also includes a control device 80, which is arranged on the frame 21. The control device 80 is electrically connected to the support mechanism 20, the film supply unit 30, the staining liquid injection unit 40, the cover glass processing unit 50 and the knocking execution unit 60.

[0077] The control device 80 controls the rotation and movement of the rack 21 through electrical connections, ensuring that each functional unit can be accurately aligned to a desired position.

[0078] The control device 80 controls the fifth driving member through electrical connection to rotate the main frame 211 relative to the base 212 .

[0079] The control device 80 controls the sixth driving member 2141 through electrical connection to move the mounting seat 213 along the sliding groove 11 .

[0080] The control device 80 controls the driver through electrical connection to adjust the extension or contraction of the telescopic rod 33 , thereby adjusting the height of the loading plate 31 .

[0081] The control device 80 can monitor the status of the limiting member 32 to ensure that the glass slide 70 is firmly fixed.

[0082] The control device 80 controls the injection pump through electrical connection to adjust the injection volume and injection speed of the dye solution.

[0083] The control device 80 can monitor the status of the injection hose 41 to ensure that the dye solution can be accurately delivered to the target location. The control device 80 controls the first driving member 51 through an electrical connection to adjust the position of the movable clamp 53 to achieve the clamping and placement of the cover glass 71.

[0084] The control device 80 can monitor the status of the fixed clamp 52 to ensure the stability of the cover glass 71 .

[0085] The control device 80 controls the first telescopic drive member 62 via an electrical connection to adjust the striking force and frequency of the striking member 61. The control device 80 controls the control unit of the striking execution unit 60 via an electrical connection to adjust the striking force and frequency. The preferred embodiments of the present disclosure have been described in detail above with reference to the accompanying drawings. However, the present disclosure is not limited to the specific details of the aforementioned embodiments. Within the scope of the technical concept of the present disclosure, various simple variations of the technical solution of the present disclosure may be made, and these simple variations all fall within the scope of protection of the present disclosure.

[0086] It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any appropriate manner without contradiction. In order to avoid unnecessary repetition, the present disclosure will not further describe various possible combinations.

[0087] In addition, the various embodiments of the present disclosure may be arbitrarily combined, and as long as they do not violate the concept of the present disclosure, they should also be regarded as the contents disclosed by the present disclosure.

Claims

1. An automatic film-making device, characterized in that: It comprises an operating table (10), a supporting mechanism (20), a film supply unit (30), a dye solution injection unit (40), a cover glass processing unit (50), and a knocking execution unit (60); The support mechanism (20) comprises a frame (21), a first operating arm (22) and a second operating arm (23); the frame (21) is rotatably and movably connected to the operating table (10); the first operating arm (22) and the second operating arm (23) are respectively provided on opposite sides of the frame (21); a first end of the first operating arm (22) is connected to the frame (21); a second end of the first operating arm (22) is provided with the dyeing liquid injection unit (40) and the cover glass processing unit (50); a first end of the second operating arm (23) is connected to the frame (21); and a second end of the second operating arm (23) is provided with the knocking execution unit (60); The slide supply unit (30) is arranged on the operating table (10) and is used to carry a glass slide (70) and a cover glass (71); the staining liquid injection unit (40) is used to inject staining liquid into tissue cells located on the glass slide (70); The cover glass processing unit (50) is used to store the cover glass (71) and place the cover glass (71) on the slide glass (70); The knocking execution unit (60) comprises a knocking member (61), a telescopic driving member (62), and a control unit for controlling the telescopic speed of the telescopic driving member (62); the second end of the second operating arm (23) is provided with the telescopic driving member (62); the driving end of the telescopic driving member (62) is connected to the knocking member (61); the telescopic driving member (62) can drive the knocking member (61) to knock the cover glass (71) located on the film supply unit (30) to promote the uniform distribution of tissue cells on the cover glass (71).

2. The automatic film-making device according to claim 1, characterized in that: The knocking member (61) comprises a knocking plate (611) and two knocking portions (612) arranged at the bottom of the knocking plate (611); The two knocking parts (612) are arranged at intervals on the same level; Two grooves (613) are formed at the bottom of the knocking plate (611), and one knocking portion (612) is correspondingly provided in each of the grooves (613); A telescopic rod (33) and a spring (615) extending in a thickness direction perpendicular to the groove (613) are provided in each groove (613); the spring (615) is sleeved on the telescopic rod (33); and the two ends of the telescopic rod (33) are respectively connected to the knocking portion (612) and the bottom of the groove (613).

3. The automatic film-making device according to claim 1, characterized in that: The automatic slide making device further comprises a connecting rod (72), the cover glass processing unit (50) comprises a first driving member (51), a fixed clamp (52), and a movable clamp (53), and the staining liquid injection unit (40) comprises a liquid storage tank, an injection hose (41), and an injection pump; The fixed clamp (52) and the movable clamp (53) are relatively arranged on the bottom surface of the second end of the first operating arm (22); the driving end of the first driving member (51) is connected to the side of the movable clamp (53) away from the fixed clamp (52); the first driving member (51) is configured to drive the movable clamp (53) to move in a direction close to or away from the fixed clamp (52); the movable clamp (53) has a first position close to the fixed clamp (52) and a second position away from the fixed clamp (52); The first operating arm (22) is formed with a receiving cavity for receiving the liquid storage tank and the injection pump. The first end of the injection hose (41) passes through the first operating arm (22) and is connected to the liquid storage tank through the injection pump. One end of the connecting rod (72) is connected to a side of the movable clamp (53) away from the fixed clamp (52), and the other end of the connecting rod (72) is connected to the second end of the injection hose (41). Wherein, in the first position, the second end of the injection hose (41) faces the slide (70) located on the slide supply unit (30).

4. The automatic film-making device according to claim 3, characterized in that: The first operating arm (22) is configured to be able to adjust the positions of the coverslip processing unit (50) and the dyeing liquid injection unit (40) in the horizontal direction and the vertical direction, and the second operating arm (23) is configured to be able to adjust the position of the knocking execution unit (60) in the horizontal direction and the vertical direction.

5. The automatic film-making device according to claim 4, characterized in that: The first operating arm (22) comprises a first connecting member (221), a first joint (222) and a first rocker arm (223); a first end of the first connecting member (221) is connected to a side wall of the frame (21); a second end of the first connecting member (221) is connected to the first joint (222); a first end of the first rocker arm (223) is hinged to the first joint (222); and a second end of the first rocker arm (223) is provided with the cover glass processing unit (50) and the dye solution injection unit (40); The second operating arm (23) comprises a second connecting member (231), a second joint (232), a second rocker arm (233), a third joint (234) and a third rocker arm (235), wherein the first end of the second connecting member (231) is connected to the side wall of the frame (21), the second end of the second connecting member (231) is connected to the second joint (232), the first end of the second rocker arm (233) is hinged to the second joint (232), the third joint (234) is connected to the second end of the second rocker arm (233), the first end of the third rocker arm (235) is hinged to the third joint (234), and the second end of the third rocker arm (235) is provided with the knocking execution unit (60).

6. The automatic film-making device according to claim 5, characterized in that: The first operating arm (22) further includes a second driving member, and the second operating arm (23) further includes a third driving member and a fourth driving member; The second driving member is in transmission connection with the first rocker arm (223) to drive the first rocker arm (223) to rotate relative to the frame (21) and change the angle between the first rocker arm and the frame (21); The third driving member is in transmission connection with the second rocker arm (233) to drive the second rocker arm (233) to rotate relative to the frame (21) and change the angle between the second rocker arm and the frame (21); The fourth driving member is in transmission connection with the third rocker arm (235) to drive the third rocker arm (235) to rotate relative to the second rocker arm (233) and change the angle between the third rocker arm (235) and the second rocker arm (233).

7. The automatic film-making device according to claim 1, characterized in that: The film supply unit (30) comprises a loading plate (31), two limiting members (32) and a telescopic mechanism; The two limiting members (32) are arranged on the top of the object carrier plate (31) and are respectively located at two opposite corners of the slide glass (70); The telescopic mechanism comprises a driver and a telescopic rod (33), wherein the driver is located in a groove (613) on the operating table (10), the telescopic rod (33) is vertically arranged, the bottom of the telescopic rod (33) is in transmission connection with the driver, and the driver can drive the telescopic rod (33) to extend or shorten, and the loading plate (31) is connected to the top of the telescopic rod (33).

8. The automatic film-making device according to claim 1, characterized in that: The frame (21) includes a main frame (211), a base (212), a fifth driving member, a mounting seat (213) and a driving mechanism (214); The fifth driving member is located in the main frame (211), and the fifth driving member is configured to drive the main frame (211) to be rotatably connected to the base (212); The top of the operating table (10) is provided with a slide groove (11) extending to the bottom thereof, and the base (212) is slidably connected to the slide groove (11); The driving mechanism (214) includes a sixth driving member (2141) and a transmission assembly, and the output shaft of the driving member is connected to the mounting seat (213) through the transmission assembly, so that the mounting seat (213) can move on the workbench along the length direction of the slide groove (11).

9. The automatic film-making device according to claim 8, characterized in that: The automatic film-making device further comprises a first mounting plate (73) and a second mounting plate (74); the transmission assembly comprises a screw (2142), a moving block (2143), two mounting blocks (2144), a driving sprocket (2145), a driven sprocket (2146) and a chain (2147); The first mounting plate (73) is mounted at the bottom of the opening close to the chute (11), the two mounting blocks (2144) are both located below the bottom of the operating table (10), one of the two mounting blocks (2144) is arranged on the first mounting plate (73), and the other of the two mounting blocks (2144) is arranged at the bottom of the operating table (10); The second mounting plate (74) is arranged at the bottom of the operating table (10), the sixth driving member (2141) is mounted on the second mounting plate (74), and the driving end of the sixth driving member (2141) is sleeved with the driving sprocket (2145); the two ends of the screw rod (2142) are respectively passed through the two mounting blocks (2144) and are rotatably connected to the two mounting blocks (2144), the driven sprocket (2146) is sleeved on the outward end of the screw rod (2142), and the chain (2147) is rotatably sleeved between the driving sprocket (2145) and the driven sprocket (2146); The moving block (2143) is installed at the bottom of the mounting seat (213), the moving block (2143) is located between the two mounting blocks (2144), and the moving block (2143) is movably connected to the screw rod (2142).

10. The automatic film-making device according to any one of claims 1 to 9, characterized in that: The automatic film-making device further includes a control device (80); The control device (80) is arranged on the frame (21), and the control device (80) is electrically connected to the support mechanism (20), the film supply unit (30), the dyeing liquid injection unit (40), the cover glass processing unit (50), and the knocking execution unit (60).

Images