Immunoassay analyzer

Abstract

The utility model discloses an immunity analyzer, which belongs to the technical field of immunity analysis and detection, and comprises an upper cover assembly and a lower cover, the lower cover is provided with a detection mechanism, the detection mechanism comprises a bottom plate and a support plate, the support plate is provided with a detector, the detector comprises a detection head facing downwards, and the detection head is provided with an opening. The bottom plate is provided with a movable card feeding mechanism for inserting a reagent card below the detector, the card feeding mechanism comprises a clamping seat and a sliding seat, the clamping seat is provided with a pair of clamping columns, a clamping groove for inserting and fixing the reagent card is formed between the pair of clamping columns, the clamping columns are provided with limiting ribs at the upper parts of the side walls of the clamping groove, and the rear ends of the clamping columns are provided with limiting plates; after the reagent card is inserted through the card slot, the upper part of the reagent card is limited through the upper part of the limiting rib, the end part of the reagent card is limited through the limiting plate, and the reagent card inserted through the card feeding mechanism moves below the detection head for scanning detection. The device is small in size, convenient, practical, low in cost price and suitable for application places with small demand quantity.

Description

Technical Field

[0001] The utility model relates to the technical field of immunoassay detection, in particular to an immunoassay analyzer. Background Art

[0002] The immunoassay analyzer uses the principle of optical detection to detect cells, proteins, enzymes, and metabolites in the sample through an optical system. The biochemical immunoassay analyzer is based on fluorescent immunochromatography technology and uses fluorescent immunochromatography technology for detection. The analyte in the sample forms an immune complex with the fluorescent probe, and after a chromatography process, it is solidified in the detection area (T line) and quality control area (C line) of the fluorescent immunoassay test strip. Insert the reacted reagent card into the detection socket of the analyzer, and the excitation light source is irradiated to the detection area and quality control area of ​​the reagent card, exciting the solidified fluorescent complex to emit fluorescence. The fluorescence is detected by the photodiode and converted into current. The current strength is proportional to the fluorescence intensity. The analyzer automatically calculates the concentration of the sample to be tested by analyzing the current strength.

[0003] Immunoassay analyzers are widely used, especially in hospitals. Existing immunoassay analyzers are often large in size and expensive in order to meet the needs of large-scale and rapid testing. Due to their large size and high price, existing immunoassay analyzers are often not widely used in small clinics, rural clinics and other places with small demand. Therefore, in order to meet the application of small clinics, rural clinics and other places with small demand, it is necessary to design a simple, small and relatively inexpensive immunoassay analyzer. Summary of the Invention

[0004] The utility model aims to provide a simple, small and relatively cheap immunoassay analyzer, aiming to solve the problem that existing immunoassay analyzers are large in size and high in price.

[0005] In response to this, the technical solution provided by the present invention is as follows: an immunoassay analyzer, comprising an upper cover assembly and a lower cover, wherein the upper cover assembly and the lower cover form a closed accommodating cavity for installing an internal structure, the lower cover is provided with a detection mechanism located in the accommodating cavity, the detection mechanism comprising a bottom plate and a support plate connected to the upper portion of the bottom plate, the support plate is provided with a detector, the detector comprising a downward-facing detection head, the bottom plate is provided with a movable card feeding mechanism for inserting a reagent card below the detector, the card feeding mechanism comprising a card seat and a sliding seat, the card seat having a pair of card posts, a card slot for inserting and fixing the reagent card is formed between the pair of card posts, the card post is provided with a limiting rib on the upper portion of the side wall of the card slot, and a limiting plate is provided at the rear end of the card post, after the reagent card is inserted through the card slot, the upper portion of the reagent card is limited by the upper portion of the limiting rib, and the end of the reagent card is limited by the limiting plate, and the inserted reagent card is moved below the detection head for scanning and detection by means of the card feeding mechanism.

[0006] Furthermore, the base plate is mounted with a power mechanism for moving the card feeding mechanism. The power mechanism includes a servo motor, and a screw is coaxially connected to the power output shaft of the servo motor. The card feeding mechanism includes a screw sleeve connected to the bottom of the sliding seat, and the screw sleeve is mounted on the screw. The rotation of the servo motor drives the screw, via the screw sleeve, to move the card feeding mechanism, thereby moving the reagent card under the detection head for scanning and detection.

[0007] Furthermore, a slide bar for sliding the card feeding mechanism is installed on the bottom plate, and a slider corresponding to the slide bar is provided at the bottom of the sliding seat of the card feeding mechanism, and the slider is slidably fitted with the slide bar.

[0008] Furthermore, the upper cover assembly includes an upper cover, an operation panel mounting groove is opened on the upper surface of the upper cover, an operation panel for operation testing is installed in the operation panel mounting groove, and a detection movable door is provided on the front side wall surface of the upper cover to cooperate with the opening and closing of the card seat.

[0009] Furthermore, the upper cover is provided with a first hinge column on the front end side wall corresponding to the detection movable door, and the detection movable door is provided with a second hinge column corresponding to the first hinge column at its lower part, and the first hinge column and the second hinge column are elastically rotatably hingedly connected by an elastic hinge shaft.

[0010] Furthermore, a limit buckle is provided on the front side wall of the upper cover corresponding to the detection movable door for limiting the rotation of the detection movable door. When the card holder moves toward the outside of the upper cover, the card holder presses against the detection movable door, causing the detection movable door to rotate outward and open, thereby facilitating the placement of a reagent card on the card holder. When the card holder moves inward, the detection movable door rotates to the limit buckle under the elastic action of the elastic hinge shaft, causing the upper cover to close.

[0011] Furthermore, a printing paper box slot is provided at the rear end of the upper cover, and two side walls of the printing paper box slot are provided with a pair of U-shaped slots for rotating and placing the printing paper roll, and a rotatable flip cover is installed on the printing paper box slot.

[0012] Furthermore, a rectangular through slot connected to the printer is provided on the front wall of the printing paper box slot, and the printing paper in the printing paper box slot is connected to the printer through the through slot.

[0013] Furthermore, a PCBA control board is installed on the lower cover.

[0014] Furthermore, a detachable battery is provided between the PCBA control board and the detection mechanism.

[0015] Furthermore, the side walls of the lower cover are provided with an on / off switch, a power port, an external device port, a network cable port, and a USB port. The on / off switch is used to control the power on / off of the instrument; the power port is used to connect an external power source to power the instrument or charge the internal rechargeable battery; the external device port is used to connect external devices such as computers, which can then be connected to the LIS (Laboratory Information System) system of a hospital or medical institution; the network cable port is used to connect the network cable to the computer device, enabling interconnection between the instrument and the computer system; and the USB port can be used to store or copy test data to an external storage device.

[0016] Furthermore, the upper cover is provided with a scanner for identifying the test information of the reagent card, thereby facilitating better identification of the user information and the type of the reagent card during the test process, so that the analyzer can retrieve corresponding comparison data for analysis and comparison based on the information on the reagent card during analysis.

[0017] The utility model can realize rapid information entry by scanning the reagent card through the scanner, thereby facilitating the preparation of the reagent card before the test. The card feeding mechanism of the detection mechanism utilizes the movement of the card feeding mechanism to quickly open the detection movable door and extend it outside the analyzer, thereby conveniently realizing the detection inside the detection mechanism after the reagent card is inserted. After the detection and comparison, the results are displayed on the operation panel, and the detection results can also be printed out by the printer.

[0018] The utility model is designed with semi-automatic insertion and placement of reagent cards. Compared with existing immunoassay analyzers, since there is no internal sample storage mechanism, sampling mechanism, incubation mechanism, sampling mechanism, etc., the analyzer occupies a small volume, is convenient and practical, and has a low cost. It is especially suitable for small clinics, rural health centers and other application places with small demand, which greatly broadens the market application of immunoassay analyzers. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model.

[0020] Figure 2 This is a schematic diagram of the internal structure of the utility model after removing the upper cover assembly.

[0021] Figure 3 This is a schematic diagram of the exploded structure of the upper cover assembly from a top view.

[0022] Figure 4 It is a schematic diagram of the three-dimensional structure of the upper cover assembly when viewed from above.

[0023] Figure 5 for Figure 4 A is a partial enlarged schematic diagram.

[0024] Figure 6 It is a schematic diagram of the three-dimensional structure of the detection mechanism.

[0025] Figure 7 It is a schematic diagram of the three-dimensional structure of the card feeding mechanism.

[0026] Figure 8 It is a schematic diagram of the three-dimensional exploded structure of the card feeding mechanism.

[0027] Figure 9 This is one of the schematic diagrams of the detector's three-dimensional structure.

[0028] Figure 10 This is the second schematic diagram of the detector's three-dimensional structure.

[0029] Among them: 1-upper cover assembly, 11-upper cover, 111-operation panel installation slot, 112-print paper box slot, 113-U-shaped slot, 114-through slot, 115-limit buckle, 116-first hinge column, 12-operation panel, 13-detection movable door, 131-second hinge column, 132-elastic hinge shaft, 14-scanner, 15-flip cover, 16-printer, 2-lower cover, 21-on / off key, 22-power interface, 23-external device interface, 24-network cable interface, 25-USB interface , 3-detection mechanism, 31-bottom plate, 32-card feeding mechanism, 321-card seat, 321a-card column, 321b-limiting rib, 321c-limiting plate, 322-sliding seat, 323-screw sleeve, 324-slider, 33-support plate, 34-detector, 341-detection head, 342-detection PCBA board, 343-sensor, 35-screw, 36-slide, 37-screw connecting seat, 38-servo motor, 4-PCBA control board, 5-battery, 6-fan, 7-reagent card. DETAILED DESCRIPTION

[0030] The following is a brief description of the embodiments of the present invention with reference to the accompanying drawings.

[0031] An immunoassay analyzer, referring to 1- Figure 2 , including an upper cover assembly 1 and a lower cover 2, the upper cover assembly 1 and the lower cover 2 are connected together by means of snaps and screws, and a closed accommodating cavity for installing the internal structure is formed between the upper cover assembly 1 and the lower cover 2, and a detection mechanism 3 and a PCBA control board 4 are provided on the lower cover 2 in the accommodating cavity, and a removable battery 5 is provided between the PCBA control board 4 and the detection mechanism 3, and the battery 5 is used to power the detection mechanism 3 and the PCBA control board 4. The battery 5 is a rechargeable battery, and the battery 5 can also use an ordinary battery. The battery 5 is detachable, which is convenient for replacing the battery 5, the upper cover assembly 1, refer to Figure 3 、 Figure 4 , including an upper cover 11, an operation panel mounting groove 111 is opened on the upper surface of the upper cover 11, and an operation panel 12 for operating the test is installed in the operation panel mounting groove 111, and a detection movable door 13 is provided on the front side wall surface of the upper cover 11 for opening and closing with the card holder 321, and a scanner 14 for identifying the test information of the reagent card 7 is provided on the upper cover 11, and the scanner 14 and the detection movable door 13 are on the same side wall surface. When the reagent card 7 to be tested is tested, the scanner 14 is first used to scan the information of the QR code attached to the card, and then the user information and the type of the reagent card 7 carried by the card are identified, so that the analyzer can retrieve the standard curve data of the corresponding test reagent according to the information of the reagent card 7 during analysis, which is convenient for comparing the electronic numbers and concentrations transmitted after the test, through the operation panel 12, and then through the card feeding mechanism 32 extending from the inside of the detection movable door 13 for measurement and detection.

[0032] Among them, the detection mechanism 3 is used to receive the reagent card 7, and scan the sample information on the reagent card 7 through the laser emitter. After scanning and detection, the detected fluorescence is converted into current by the photodiode detection, and the current size is converted into digital information and transmitted to the PCBA control board 4. The PCBA control board 4 analyzes and compares the standard curve data of the test reagent to obtain the value of the detection concentration and displays it on the operation panel 12. Figure 6 , the detection mechanism 3, includes a base plate 31 and a support plate 33 connected to the upper part of the base plate 31, and a detector 34 is installed on the support plate 33. The detector 34, refer to Figure 9 、 Figure 10 , including a downward-facing detection head 341 and a detection PCBA board 342. The detection head 341 is used to excite the light source and irradiate the reagent card 7, exciting the solidified fluorescent complex to emit fluorescence. The detection PCBA board 342 converts the detection into current, and the current strength is proportional to the fluorescence intensity to obtain digital information, and sends the digital information to the PCBA control board 4 for further analysis, thereby automatically calculating the concentration of the sample to be tested. The detector 34 is provided with a sensor 343. The sensor 343 is used to sense whether the card feeding mechanism 32 is plugged with a reagent card 7. When the sensor 343 senses that the card mechanism 32 is plugged with a reagent card 7, the detection PCBA board 342 controls the power mechanism to move the card feeding mechanism 32 according to the detection moving speed, and at the same time opens the detection head 341 to synchronously detect the moving reagent card 7.

[0033] The bottom plate 31 is provided with a movable card feeding mechanism 32 for inserting the reagent card 7 below the detector 34. The card feeding mechanism 32 is shown in FIG. Figure 7 、 Figure 8 , including a card seat 321 and a sliding seat 322. The card seat 321 has a pair of card posts 321a. A card slot for the reagent card 7 to be inserted and fixed is formed between the pair of card posts 321a. The card post 321a is provided with a limiting rib 321b on the upper part of the side wall of the card slot, and a limiting plate 321c is provided at the rear end of the card post 321a. After the reagent card 7 is inserted through the card slot, the upper part of the reagent card 7 is limited by the upper part of the limiting rib 321b, and the end of the reagent card 7 is limited by the limiting plate 321c. The movable card feeding mechanism 32 moves the inserted reagent card 7 to the bottom of the detection head 341 for scanning and detection.

[0034] Among them, a power mechanism for the movement of the card feeding mechanism 32 is installed on the bottom plate 31, and the power mechanism includes a servo motor 38. A screw 35 is coaxially connected to the power output shaft of the servo motor 38. In order to ensure the stability of the screw 35, a screw connecting seat 37 for stabilizing the screw 35 is installed on the bottom plate 31, and the screw 35 and the screw connecting seat 37 are rotatably connected. Correspondingly, the card feeding mechanism 32 includes a screw sleeve 323 connected to the bottom of the sliding seat 322, and the screw sleeve 323 is sleeved on the screw 35. 38 rotates, the screw rod 35 uses the screw rod sleeve 323 to drive the card feeding mechanism 32 to move, and the card feeding mechanism 32 moves the reagent card 7 to the bottom of the detection head 341 for scanning and detection. During the movement, in order to ensure the smooth movement of the card feeding mechanism 32, a slide bar 36 for the card feeding mechanism 32 to slide is installed on the bottom plate 31, and a slider 324 corresponding to the slider 36 is provided at the bottom of the sliding seat 322 of the card feeding mechanism 32. The slider 324 slides with the slider 36 to ensure that the card feeding mechanism 32 can move under the action of the servo motor 38.

[0035] In this embodiment, a fan 6 is provided at the rear end of the power mechanism for ventilation and cooling the servo motor 38 of the power mechanism during operation, thereby avoiding heat accumulation inside the small-sized immunoassay analyzer.

[0036] In this embodiment, refer to Figure 5 When the card holder 321 moves to the inside, the detection movable door 13 rotates to the limit buckle 115 under the elastic action of the elastic hinge shaft 132, so that the upper cover 11 is closed.

[0037] In this embodiment, a test result printing function is also provided, refer to Figure 3 、 Figure 4 The rear end of the upper cover 11 is provided with a printing paper box slot 112. The two side walls of the printing paper box slot 112 are provided with a pair of U-shaped slots 113 for rotating and placing the printing paper roll. The front wall of the printing paper box slot 112 is provided with a rectangular through slot 114 connected to the printer 16. The printing paper in the printing paper box slot 112 is connected to the printer 16 through the through slot 114. At the same time, a rotatable flip cover 15 is installed on the printing paper box slot 112 to facilitate the replacement of printing paper.

[0038] In this embodiment, multiple interfaces are also provided, including an on / off switch 21, a power interface 22, an external device interface 23, a network cable interface 24, and a USB interface 25, which are arranged on the side wall of the lower cover 2. The on / off switch 21, the power interface 22, the external device interface 23, the network cable interface 24, and the USB interface 25 are all electrically connected to the PCBA control board 4. The on / off switch 21 is used to control the power on / off of the instrument; the power interface 22 is used to plug in an external power source to power the instrument or charge the internal rechargeable battery; the external device interface 23 is used to connect external devices such as computers, and then connect to the LIS (Laboratory Information System) system of a hospital or medical institution; the network cable interface 24 is used to connect the network cable to the computer device to achieve interconnection between the computer system of the instrument and the device; and the USB interface 25 can be used to store or copy test data to an external storage device.

[0039] The above embodiments merely represent implementation methods of the present invention. Although the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the present invention. It should be noted that a person skilled in the art may make various modifications and improvements without departing from the concept of the present invention, and these modifications and improvements are all within the scope of protection of the present invention.

Claims

1. An immunoassay analyzer, characterized in that: The card holder is provided with a plurality of movable cards, each of which is provided with a plurality of movable cards, and the movable cards are provided with a plurality of movable cards.

2. An immunoassay analyzer according to claim 1, characterized in that: A slide bar for sliding the card feeding mechanism is installed on the bottom plate. The bottom of the sliding seat of the card feeding mechanism is provided with a slider corresponding to the slide bar, and the slider is slidably matched with the slide bar.

3. The immunoassay analyzer according to claim 1, wherein: The upper cover assembly includes an upper cover, an upper surface of which is provided with an operation panel installation groove, an operation panel for operation testing is installed in the operation panel installation groove, and a detection movable door is provided on the front side wall surface of the upper cover to cooperate with the opening and closing of the card seat.

4. An immunoassay analyzer according to claim 3, characterized in that: The upper cover is provided with a first hinge column on the front end side wall corresponding to the detection movable door, and the detection movable door is provided with a second hinge column corresponding to the first hinge column at its lower part, and the first hinge column and the second hinge column are elastically rotatably hingedly connected by an elastic hinge shaft.

5. The immunoassay analyzer according to claim 3, wherein: A limiting buckle for limiting the rotation of the detection movable door is further provided on the front end side wall of the upper cover corresponding to the detection movable door.

6. The immunoassay analyzer according to claim 1, characterized in that: A printing paper box slot is provided at the rear end of the upper cover, and two side walls of the printing paper box slot are provided with a pair of U-shaped slots for rotating and placing the printing paper roll, and a rotatable flip cover is installed on the printing paper box slot.

7. An immunoassay analyzer according to claim 6, characterized in that: The front wall of the printing paper box slot is provided with a rectangular through slot connected to the printer, and the printing paper in the printing paper box slot is connected to the printer through the through slot.

8. The immunoassay analyzer according to claim 1, wherein: The lower cover is provided with a PCBA control board installed.

9. The immunoassay analyzer according to claim 1, characterized in that: The side wall of the lower cover is provided with an on / off key, a power interface, an external device interface, a network cable interface and a USB interface in sequence.

10. The immunoassay analyzer according to claim 3, characterized in that: The upper cover is provided with a scanner for identifying the test information of the reagent card.

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