Membrane type liquid-based thin-layer cell sheet making machine

Abstract

The utility model discloses a membrane type liquid-based thin-layer cell slide making machine which comprises a frame body, and a liquid taking pipe fixing mechanism, a liquid storage pipe fixing mechanism, a separating mechanism, a liquid suction auxiliary mechanism and a slide moving frame which are arranged on the frame body, the separating mechanism is used for driving the liquid taking pipe fixing mechanism to be separated from or close to the liquid storage pipe fixing mechanism; the liquid suction auxiliary mechanism is installed on the supporting plate and comprises an overturning mechanism and an overturning plate, a sealing ring matched with the liquid storage pipe is installed on the overturning plate, and a liquid suction opening communicated with the sealing ring is formed in the overturning plate; the liquid suction auxiliary mechanism is arranged, the sealing ring on the turning plate can be tightly attached to the bottom of the liquid storage bottle through the turning mechanism, and therefore the situation of insufficient pressure suction caused by poor sealing performance is prevented, the situation of residual liquid is reduced, and the slide production efficiency is improved.

Description

Technical Field

[0001] The utility model relates to the field of cell slice making equipment, in particular to a membrane type liquid-based thin layer cell slice making machine. Background Art

[0002] The production process of the membrane liquid-based thin layer cell slide making machine is to extract the cell base liquid in the filter membrane cup through negative pressure, let the cells remain on the filter membrane, and then transfer them to the slide. If the liquid storage bottle and the liquid aspiration device are not sealed during aspiration, insufficient suction pressure will occur, and there will easily be residual liquid in the membrane cup. The cell base liquid in the filter membrane cup needs to be sucked out through the liquid suction tube head. When different cells need to be transferred, if the liquid suction tube head is not cleaned in time, different sample cells will be mixed, resulting in inaccurate test results. However, frequent cleaning of the liquid suction tube head is very inconvenient. Utility Model Content

[0003] The utility model provides a membrane-type liquid-based thin layer cell slice making machine, which can at least solve the problems pointed out in the background technology.

[0004] A membrane-type liquid-based thin-layer cell slide making machine includes a frame and a device mounted on the frame:

[0005] A liquid collection tube fixing mechanism, used for fixing the liquid collection tube;

[0006] A liquid storage tube fixing mechanism, used for fixing the liquid storage tube;

[0007] The separation mechanism includes a support plate for mounting the liquid storage tube fixing mechanism; the separation mechanism is used to drive the liquid collection tube fixing mechanism and the liquid storage tube fixing mechanism to separate or move closer;

[0008] A liquid suction auxiliary mechanism is installed on the support plate, which includes a turning mechanism and a flap, wherein a sealing ring cooperating with the liquid storage tube is installed on the flap, and a liquid suction port connected to the sealing ring is opened on the flap; and

[0009] The slide moving rack comprises a slide rack and a moving mechanism, wherein the moving mechanism is used to drive the slide rack to move between a liquid taking tube fixing mechanism and a liquid storing tube fixing mechanism.

[0010] The liquid collection tube fixing mechanism is mounted on the mounting bracket at the top of the frame, and the liquid storage tube fixing mechanism is mounted on the support plate. Both the liquid collection tube fixing mechanism and the liquid storage tube fixing mechanism include two symmetrically distributed fixing blocks and a fixing assembly that drives the two fixing blocks to move relative to or away from each other.

[0011] The two fixing blocks are both provided with a semicircular groove which cooperates with the liquid taking tube.

[0012] The fixing assembly includes a screw rod and a motor that drives the screw rod to rotate. The output end of the motor is in transmission connection with the screw rod. The screw rod has two parts with opposite thread directions. The two fixing blocks are respectively connected to the two parts of the screw rod.

[0013] Preferably, a guide rod 1 is installed on the mounting frame and the supporting plate respectively, and a guide hole that cooperates with the guide rod 1 is opened on the fixing block.

[0014] Preferably, the separation mechanism includes a second screw rod and a second motor for driving the second screw rod to rotate. The output end of the second motor is transmission-connected to the second screw rod. The support plate is cooperatively connected to the second screw rod. A second guide rod is also fixedly mounted on the frame. A guide hole cooperating with the second guide rod is provided on the support plate.

[0015] Preferably, the moving mechanism includes a screw rod three and a motor three for driving the screw rod three to rotate, and the slide rack is mounted on the screw rod three.

[0016] Preferably, the flipping mechanism includes a rotating shaft rotatably mounted on the support plate and a motor 4 for driving the rotating shaft to rotate, and the flip plate is fixedly mounted on the rotating shaft.

[0017] Compared with the existing technology, the beneficial effects of the present invention are: the present invention is provided with a liquid suction auxiliary mechanism, which can make the sealing ring on the flip plate fit tightly with the bottom of the liquid storage bottle through the flip mechanism, thereby preventing insufficient suction pressure due to poor sealing, reducing the occurrence of residual liquid, and improving the production efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a structural diagram of one of the perspectives of the present invention;

[0019] Figure 2 This is a structural diagram of the utility model from another perspective;

[0020] Figure 3 This is a structural diagram of the liquid collection tube fixing mechanism and the liquid storage tube fixing mechanism of the present invention after being separated;

[0021] Figure 4 This is a structural diagram of the liquid storage tube fixing mechanism and the liquid suction auxiliary mechanism of the present invention;

[0022] Figure 5 It is a cross-sectional view of the sealing ring of the present invention.

[0023] Description of reference numerals:

[0024] 1-frame, 2-mounting frame, 3-support plate, 4-screw rod 2, 5-motor 2, 6-guide rod 2, 7-slide rack, 8-screw rod 3, 9-motor 3, 10-flip plate, 11-sealing ring, 12-liquid suction port, 13-rotating shaft, 14-motor 4, 21-fixed block, 22-screw rod 1, 23-motor 1, 24-guide rod 1, 25-semicircular groove. DETAILED DESCRIPTION

[0025] A specific embodiment of the present invention will be described in detail below with reference to the accompanying drawings, but it should be understood that the protection scope of the present invention is not limited by the specific embodiment.

[0026] like Figures 1 to 5 As shown, the embodiment of the present invention provides a membrane-type liquid-based thin layer cell slide making machine, comprising a frame 1 and a liquid collection tube fixing mechanism, a liquid storage tube fixing mechanism, a separation mechanism, a liquid aspiration auxiliary mechanism and a slide moving frame installed on the frame 1;

[0027] A mounting bracket 2 for mounting a liquid extraction pipe fixing mechanism is fixedly mounted on the top of the frame 1;

[0028] The separation mechanism includes a support plate 3, a screw rod 2 4, and a motor 2 5 that drives the screw rod 2 4 to rotate. The output end of the motor 2 5 is connected to the screw rod 2 4 in a transmission manner. The support plate 3 is connected to the screw rod 2 4. A guide rod 2 6 is fixedly mounted on the frame 1. A guide hole that cooperates with the guide rod 2 6 is opened on the support plate 3.

[0029] The screw rod 2 4 and the motor 2 5 are connected via a belt transmission mechanism (not shown in the figure);

[0030] The liquid storage tube fixing mechanism is installed on the support plate 3, so the separation mechanism can drive the liquid collection tube fixing mechanism to separate from or move closer to the liquid storage tube fixing mechanism. After the cell base liquid is sucked out by the external aspiration device, the liquid collection tube fixing mechanism is separated from the liquid storage tube fixing mechanism by the separation mechanism, thereby providing space for the transfer of the slide;

[0031] The slide moving rack includes a slide rack 7 and a moving mechanism. The slide rack 7 is provided with a mounting slot for placing a slide. The moving mechanism is used to drive the slide rack 7 to move between the liquid collection tube fixing mechanism and the liquid storage tube fixing mechanism. The moving mechanism includes a screw rod 3 8 and a motor 3 9 that drives the screw rod 3 8 to rotate. The motor 3 9 is fixedly mounted on the rack body 1. The slide rack 7 is mounted on the screw rod 3 8. The slide rack 7 is slidably arranged on the lower side of the mounting frame 2. Therefore, when the screw rod 3 8 rotates, the slide rack 7 moves in the length direction of the screw rod 3 8.

[0032] The liquid suction auxiliary mechanism is also installed on the support plate 3 and moves synchronously with the liquid storage tube fixing mechanism. The liquid suction auxiliary mechanism includes a turning mechanism and a flap 10. The flap 10 is equipped with a sealing ring 11 that cooperates with the bottom of the liquid storage tube. The flap 10 is provided with a liquid suction port 12 that is connected to the sealing ring 11. The liquid suction port 12 is connected to an external liquid suction device;

[0033] The sealing ring 11 of this embodiment is annular, and the flip mechanism allows the sealing ring 11 to fit tightly against the liquid storage tube, preventing air leakage and thus avoiding the occurrence of residual liquid. This eliminates the need for a pipette tip, thereby improving efficiency.

[0034] The flip mechanism includes a rotating shaft 13 rotatably mounted on the support plate 3 and a motor 14 for driving the rotating shaft 13 to rotate. The flip plate 10 is fixedly mounted on the rotating shaft 13.

[0035] The motor 4 14 of this embodiment is connected to the rotating shaft 13 by means of gear transmission, and the bracket of the motor 4 14 is fixed on the support plate 3;

[0036] The liquid collection tube fixing mechanism is used to fix the liquid collection tube, and the liquid storage tube fixing mechanism is used to fix the liquid storage tube; both the liquid collection tube fixing mechanism and the liquid storage tube fixing mechanism include two symmetrically distributed fixing blocks 21 and a fixing assembly;

[0037] Both fixing blocks 21 are provided with semicircular grooves 25 for cooperating with the liquid extraction tube / liquid storage tube;

[0038] The fixing assembly includes a screw rod 22 and a motor 23 that drives the screw rod 22 to rotate. The output end of the motor 23 is in transmission connection with the screw rod 22. The screw rod 22 has two parts with opposite thread directions. The two fixing blocks 21 are respectively connected to the two parts of the screw rod 22. When the screw rod 22 rotates, the two fixing blocks 21 can move relative to each other or move away from each other.

[0039] A guide rod 24 is installed on the mounting frame 2 and the supporting plate 3 respectively, and a guide hole that cooperates with the guide rod 24 is opened on the fixing block 21.

[0040] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above and that the present invention can be implemented in other specific forms without departing from the spirit and essential features of the present invention. Therefore, the embodiments should be considered in all respects as illustrative and non-restrictive, and the scope of the present invention is defined by the appended claims, not the foregoing description, and all variations within the meaning and range of equivalents of the claims are intended to be encompassed within the present invention. Any reference sign in a claim should not be construed as limiting the claim to which it relates.

[0041] In addition, it should be understood that although this specification is described in terms of implementation methods, not every implementation method contains only one independent technical solution. This narrative method of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment can also be appropriately combined to form other implementation methods that can be understood by those skilled in the art.

Claims

1. A membrane-type liquid-based thin layer cell preparation machine, characterized in that: It includes a frame and the following components mounted on the frame: A liquid collection tube fixing mechanism, used to fix the liquid collection tube; A liquid storage tube fixing mechanism, used for fixing the liquid storage tube; The separation mechanism includes a support plate for mounting the liquid storage tube fixing mechanism; the separation mechanism is used to drive the liquid collection tube fixing mechanism and the liquid storage tube fixing mechanism to separate or move closer; The liquid suction auxiliary mechanism is installed on the supporting plate, which includes a turning mechanism and a flap, wherein a sealing ring cooperating with the liquid storage tube is installed on the flap, and a liquid suction port connected to the sealing ring is opened on the flap; as well as The slide moving rack comprises a slide rack and a moving mechanism, wherein the moving mechanism is used to drive the slide rack to move between a liquid taking tube fixing mechanism and a liquid storing tube fixing mechanism.

2. A membrane-type liquid-based thin layer cell slide making machine as claimed in claim 1, characterized in that: The liquid collection tube fixing mechanism is installed on the mounting bracket on the top of the frame, and the liquid storage tube fixing mechanism is installed on the support plate. Both the liquid collection tube fixing mechanism and the liquid storage tube fixing mechanism include two symmetrically distributed fixing blocks and a fixing component that drives the two fixing blocks to move relative to or away from each other.

3. A membrane-type liquid-based thin layer cell slide making machine as claimed in claim 2, characterized in that: The two fixing blocks are both provided with a semicircular groove which cooperates with the liquid taking tube.

4. A membrane-type liquid-based thin layer cell slide making machine as claimed in claim 2, characterized in that: The fixing assembly includes a screw rod and a motor that drives the screw rod to rotate. The output end of the motor is in transmission connection with the screw rod. The screw rod has two parts with opposite thread directions. The two fixing blocks are respectively connected to the two parts of the screw rod.

5. A membrane-type liquid-based thin layer cell slide making machine as claimed in claim 2, characterized in that: A guide rod 1 is respectively installed on the mounting frame and the supporting plate, and a guide hole matched with the guide rod 1 is opened on the fixing block.

6. A membrane-type liquid-based thin layer cell slide making machine as claimed in claim 1, characterized in that: The separation mechanism includes a second screw rod and a second motor that drives the second screw rod to rotate. The output end of the second motor is transmission-connected to the second screw rod. The support plate is cooperatively connected to the second screw rod. A second guide rod is also fixedly mounted on the frame. A guide hole that cooperates with the second guide rod is opened on the support plate.

7. A membrane-type liquid-based thin layer cell slide making machine as claimed in claim 1, characterized in that: The moving mechanism includes a screw rod three and a motor three for driving the screw rod three to rotate, and the slide rack is mounted on the screw rod three.

8. The membrane-type liquid-based thin layer cell slide making machine according to claim 1, characterized in that: The flip mechanism includes a rotating shaft rotatably mounted on the support plate and a motor 4 for driving the rotating shaft to rotate, and the flip plate is fixedly mounted on the rotating shaft.

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