Novel electric tissue liquid nitrogen grinder

Abstract

The utility model discloses a novel electric tissue liquid nitrogen grinder which comprises a central base and an elastic lifting column which is vertically arranged in the center of the central base, a plurality of grinding pipe placing grooves which are annularly arranged in the central base are formed in the periphery of the elastic lifting column, and grinding pipes are placed in the grinding pipe placing grooves. A lifting table fixedly connected with a rotating motor is arranged at the upper end of the elastic lifting column, the output end of the rotating motor is connected with a driving gear rotationally connected with the lifting table, the driving gear is in meshed connection with a plurality of driven gears rotationally connected with the lifting table, and the driven gears are fixedly connected with rotating shafts; and the lower end of the rotating shaft is connected with a grinding rod matched with the grinding pipe through a detachable connecting piece. The animal and plant tissue sample grinding device facilitates batch grinding treatment of animal and plant tissue samples, improves grinding efficiency, can prevent liquid nitrogen from volatilizing too fast and tissues from splashing, and has the advantages of being short in grinding time, high in efficiency, capable of conducting batch treatment, easy to use, safe in grinding and the like.

Description

Technical Field

[0001] The utility model relates to the technical field of medical testing equipment, in particular to a novel electric tissue liquid nitrogen grinder. Background Art

[0002] Liquid nitrogen grinders are used to crush and grind animal and plant tissues, microbial cells, and other tissues to facilitate the extraction of DNA, RNA, and proteins. These grinders are fundamental to the field of molecular biology. The samples they grind primarily consist of animal and plant tissues and microbial cell tissues. During grinding, the activity and integrity of the molecules within the tissues must be maintained. Liquid nitrogen is used as a refrigerant to maintain a low temperature within the grinding tube, rapidly freezing the tissue and preventing damage that would affect the grinding effect. Therefore, liquid nitrogen grinders require high cryogenic temperatures and grinding efficiency during tissue grinding.

[0003] However, the liquid nitrogen grinders on the market have the problem of single throughput. They can only grind one sample at a time, which makes it difficult to grind tissue samples in batches, resulting in long grinding and extraction time and low grinding efficiency. Moreover, during grinding, because the mouth of the grinding tube is large and the grinding rod is small, tissue splashing is likely to occur at the mouth of the grinding tube during the grinding process, and while some tissue material is lost, the grinding tube is also prone to temperature increase, which may cause some DNA, RNA, and protein to degrade, resulting in low extraction efficiency. Utility Model Content

[0004] In order to solve the technical problems in the prior art that liquid nitrogen grinders are not easy to grind samples in batches, the grinding and extraction time is long, the grinding efficiency is low, and the grinding tube is prone to tissue splashing and temperature rise, resulting in low extraction efficiency, the utility model provides the following technical solutions.

[0005] The utility model discloses a novel electric tissue liquid nitrogen grinder, comprising a central base and an elastic lifting column vertically arranged at the center of the central base, the outer periphery of the elastic lifting column is provided with a plurality of grinding tube placement grooves arranged in an annular manner within the central base, a grinding tube is placed in the grinding tube placement groove, the upper end of the elastic lifting column is provided with a lifting platform fixedly connected to a rotating motor, the output end of the rotating motor is connected to a driving gear rotatably connected to the lifting platform, the driving gear is meshedly connected to a plurality of driven gears rotatably connected to the lifting platform, the driven gear is fixedly connected to a rotating shaft, and the lower end of the rotating shaft is connected to a grinding rod matching the grinding tube through a detachable connecting piece.

[0006] As a further technical solution, a splash-proof ring is provided on the upper portion of the grinding rod, and the splash-proof ring covers or opens the tube opening of the grinding tube as the grinding rod rises and falls.

[0007] As a further technical solution, an insulation layer is provided on the inner wall of the grinding tube placement groove.

[0008] As a further technical solution, there are eight grinding tube placement grooves, which are evenly arranged along the circumference of the elastic lifting column.

[0009] As a further technical solution, the elastic lifting column adopts manual adjustment or electric adjustment.

[0010] As a further technical solution, the axis of the grinding tube and the axis of the grinding rod are on the same straight line.

[0011] The beneficial effects of the present invention are as follows: the central base of the present invention is connected to an elastic lifting column, and the central base is provided with multiple grinding tube placement slots, which can simultaneously place multiple grinding tubes; the upper end of the elastic lifting column is connected to a lifting platform, which is provided with multiple rotating shafts, and the lower end of each rotating shaft is detachably connected to a grinding rod, and each grinding rod corresponds to a grinding tube, which facilitates batch grinding of animal and plant tissue samples and improves grinding efficiency. The upper part of the grinding rod is provided with a splash-proof ring, which can cover the nozzle of the grinding tube or the upper end of the grinding tube placement slot to prevent liquid nitrogen from volatilizing too quickly and splashing tissues. It can be efficiently used to grind animal and plant tissues, microbial cell tissues, etc. to improve the extraction efficiency of DNA, RNA, protein, etc., and has the characteristics of short grinding time, high efficiency, batch processing, simple use, and safe grinding. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 This is a schematic structural diagram of a novel electric tissue liquid nitrogen grinder of the present utility model;

[0013] Figure 2 This is a schematic diagram of the connection of the grinding rod of the new electric tissue liquid nitrogen grinder of the utility model;

[0014] In the figure: 1-central base; 2-grinding tube placement slot; 3-elastic lifting column; 4-grinding tube; 5-grinding rod; 6-detachable connector; 7-rotating shaft; 8-driven gear; 9-driving gear; 10-rotating motor; 11-lifting platform; 12-splash ring. DETAILED DESCRIPTION

[0015] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely for the purpose of explaining the present invention and are not intended to limit the present invention. It should be noted that the embodiments and features of the embodiments of the present invention may be combined with each other unless there is a conflict.

[0016] In the description of this utility model, it should be understood that the terms "upper" and "lower" are based on the orientation or positional relationships shown in the accompanying drawings and are intended solely to facilitate the description of this utility model and simplify the description. They do not indicate or imply that the devices or components referred to must have a specific orientation, be constructed, or operate in a specific orientation. Therefore, they should not be construed as limitations on this utility model. Furthermore, the terms "first," "second," etc. are used solely for descriptive purposes and should not be construed to indicate or imply relative importance or implicitly specify the quantity of the technical features referred to. In the description of this utility model, unless otherwise specified, "plurality" means two or more.

[0017] like Figure 1 and Figure 2 As shown, the present invention provides a novel electric tissue liquid nitrogen grinder, comprising a central base 1 and a vertically arranged elastic lifting column 3 located at the center of the central base 1. The elastic lifting column 3 is equipped with a spring, which provides a certain cushioning performance in the vertical direction. The elastic lifting column 3 is manually or electrically adjustable. In this embodiment, the elastic lifting column 3 is connected to the central base 1 via a screw thread or a sliding connection via a guide column. The central base 1 is equipped with a motor to control the raising and lowering of the elastic lifting column 3. The motor drives the elastic lifting column 3 to rise or fall relative to the central base 1. The elastic lifting column 3 adopts the existing structure, so it will not be described in detail.

[0018] In a preferred embodiment, the outer periphery of the elastic lifting column 3 is provided with a plurality of annular grinding tube slots 2 located within the central base 1. These slots 2 are used to accommodate grinding tubes 4 containing liquid nitrogen and tissue samples. The inner walls of these slots are provided with a thermal insulation layer to reduce the impact of the external environment on the temperature within the grinding tubes 4. In this embodiment, there are eight grinding tube slots 2, evenly spaced along the circumference of the elastic lifting column 3. However, the number of grinding tube slots 2 is not limited to eight and may be reduced or increased, and this is not specifically limited by the present invention.

[0019] In a preferred embodiment, a lifting platform 11 is provided at the upper end of the elastic lifting column 3, and the lifting platform 11 is a hollow structure. A rotating motor 10 is fixedly connected to the upper end of the lifting platform 11. For ease of description, the upper end of the lifting platform 11 is not shown in the figure, but it should be known that the rotating motor 10 is fixed to the upper end of the lifting platform 11. The output end of the rotating motor 10 extends downward and is connected to a driving gear 9, which is rotatably connected to the bottom of the lifting platform 11. The driving gear 9 is meshed with a number of driven gears 8 that are rotatably connected to the bottom of the lifting platform 11. When there are eight rising grinding tube placement slots 2, there are also eight driven gears 8, and adjacent driven gears 8 do not contact each other. When the rotating motor 10 drives the driving gear 9 to rotate, each driven gear 8 meshed with the driving gear 9 rotates in the same direction.

[0020] Each driven gear 8 is fixedly connected to a rotating shaft 7, which extends to the lower end of the lifting platform 11. The lower end of the rotating shaft 7 is connected to a detachable connecting piece 6, which is connected to a grinding rod 5 that matches the grinding tube 4. The detachable connecting piece 6 is an existing detachable structure such as a buckle or a sleeve. Its upper end is connected to the rotating shaft 7, and its lower end is connected to the upper end of the grinding rod 5. Thus, the driven gear 8 can drive the rotating shaft 7 and the grinding rod 5 to rotate and grind.

[0021] In a preferred embodiment, a splash-proof ring 12 is provided on the upper portion of the grinding rod 5. The splash-proof ring 12 can be integrally formed with the grinding rod 5 or assembled into a ring-shaped structure on the upper portion of the grinding rod 5. The splash-proof ring 12 prevents tissue splashing in the grinding tube 4 while also insulating the grinding tube 4 to prevent temperature rise caused by excessive evaporation of liquid nitrogen. The splash-proof ring 12 can rise and fall with the grinding rod 5. When the grinding rod 5 descends, it can cover the opening of the grinding tube 4 during grinding. Alternatively, it can rise with the grinding rod 5 after grinding is completed to open the opening of the grinding tube 4. It should be understood that the axis of the grinding tube 4 and the axis of the grinding rod 5 are aligned.

[0022] When the utility model is in use, tissue samples and liquid nitrogen are placed in multiple grinding tubes 4 respectively, and the grinding tubes 4 are placed one by one in the grinding tube placement groove 2, the elastic lifting column 3 is controlled to descend, driving the lifting platform 11 to move downward so that the grinding rod 5 enters the grinding tube 4, and at the same time the splash ring 12 covers the grinding tube placement groove 2 and the top of the grinding tube 4, and the rotating motor 10 is started. The rotating motor 10 drives the multiple rotating shafts 7 to rotate simultaneously, thereby controlling the grinding rod 5 to quickly grind the tissue in the grinding tube 4.

[0023] The preferred specific implementation methods and embodiments of the present invention are described in detail above in conjunction with the accompanying drawings. However, the present invention is not limited to the above implementation methods and embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes or equivalent substitutions can be made without departing from the concept of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed herein, and all embodiments that fall within the scope of the claims of this application belong to the scope of protection of the present invention.

Claims

1. A new type of electric tissue liquid nitrogen grinder, characterized by: The invention comprises a central base (1) and an elastic lifting column (3) vertically arranged at the center of the central base (1); the outer periphery of the elastic lifting column (3) is provided with a plurality of grinding tube placement grooves (2) arranged in an annular manner and located in the central base (1); a grinding tube (4) is placed in the grinding tube placement groove (2); the upper end of the elastic lifting column (3) is provided with a lifting platform (11) fixedly connected to a rotating motor (10); the output end of the rotating motor (10) is connected to a driving gear (9) rotatably connected to the lifting platform (11); the driving gear (9) is meshedly connected to a plurality of driven gears (8) rotatably connected to the lifting platform (11); the driven gear (8) is fixedly connected to a rotating shaft (7); the lower end of the rotating shaft (7) is connected to a grinding rod (5) matching the grinding tube (4) through a detachable connecting piece (6).

2. The novel electric tissue liquid nitrogen grinder according to claim 1 is characterized in that: An anti-splash ring (12) is provided on the upper portion of the grinding rod (5), and the anti-splash ring (12) covers or opens the tube opening of the grinding tube (4) as the grinding rod (5) rises and falls.

3. The novel electric tissue liquid nitrogen grinder according to claim 1 is characterized in that: The inner wall of the grinding tube placement groove (2) is provided with a heat insulation layer.

4. The novel electric tissue liquid nitrogen grinder according to claim 1 is characterized in that: There are eight grinding tube placement slots (2) which are evenly arranged along the circumference of the elastic lifting column (3).

5. The novel electric tissue liquid nitrogen grinder according to claim 1 is characterized in that: The elastic lifting column (3) is manually adjusted or electrically adjusted.

6. The novel electric tissue liquid nitrogen grinder according to claim 1 is characterized in that: The axis of the grinding tube (4) and the axis of the grinding rod (5) are on the same straight line.

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