Two-way valve seat for chromatographic degradation
By designing a two-way valve seat for chromatography degradation, using a partition to isolate the fluid cavity and set up a sampling chamber, the problem of fluid communication in the prior art cannot be separated and sampled, and the effects of fluid separation control and drug liquid sampling are achieved.
Patent Information
- Application Number
- CN202422709513.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-07
- Publication Date
- 2025-08-29
- Estimated Expiration
- 2034-11-07
AI Technical Summary
In the existing chromatographic degradation system, the valve seat can only achieve simple fluid communication, and cannot control fluid separation and drug liquid sampling, and lacks the functions of fluid separation control and drug liquid sampling.
A two-way valve seat for chromatographic degradation is designed, including a valve seat body, a first and a second communication pipe, a separation cavity and a partition. The first and the second separation cavity are separated by a partition to realize fluid separation control, and a sampling chamber is provided on the valve seat body to facilitate sampling of the drug liquid.
It realizes the functions of fluid separation control and drug liquid sampling, and is simple and easy to manufacture. It is suitable for fluid separation and sampling during chromatographic degradation.
Smart Images

Figure CN223283954U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to a pipeline connecting valve seat, in particular to a two-way valve seat for chromatography degradation. Background Art
[0002] Pipelines are required in chromatographic degradation, and the connection between pipelines is generally achieved through a valve seat, thereby achieving fluid communication between the pipelines. In one prior art, the valve seat includes a valve seat body, a first connecting pipe, and a second connecting pipe. The valve seat body is provided with an inner cavity for fluid circulation. The first connecting pipe and the second connecting pipe are both fixedly connected to the valve seat body, and the first connecting pipe and the second connecting pipe are both connected to the inner cavity of the valve seat body. The first connecting pipe is connected to one pipeline, and the second connecting pipe is connected to another pipeline, thereby achieving fluid communication between the two pipelines. However, this valve seat can only achieve simple fluid communication, but cannot control fluid separation control and liquid sampling, and these two functions are currently in short supply in the market. Summary of the Invention
[0003] The purpose of the utility model is to solve the shortcomings of the prior art and to propose a T-shaped valve seat used in a chromatography degradation system.
[0004] In order to achieve the above-mentioned objectives, the present invention adopts the following technical solutions: a two-way valve seat for chromatographic degradation, comprising a valve seat body, a first communicating pipe, and a second communicating pipe, the valve seat body being provided with a first separation inner cavity, a second separation inner cavity, and a partition, the partition extending upward from the bottom of the first separation inner cavity or the bottom of the second separation inner cavity of the valve seat body to a preset height, thereby separating the first separation inner cavity and the second separation inner cavity, so that no fluid exchange occurs between the first separation inner cavity and the second separation inner cavity; the first communicating pipe and the second communicating pipe are both fixedly connected to the valve seat body, the first communicating pipe having a first fluid through hole, the second communicating pipe having a second fluid through hole, the first fluid through hole being connected to the first separation inner cavity, and the second fluid through hole being connected to the second separation cavity; a sampling chamber is also provided on the valve seat body, the sampling chamber having a sampling port, the sampling chamber passing through the valve seat body, and the sampling chamber being connected to the first separation inner cavity or the second separation cavity.
[0005] Furthermore, the outer surface of the partition is flush with the plane where the outer contour of the first separation cavity is located and the plane where the outer contour of the second separation cavity is located, so that the partition prevents the first separation cavity and the second separation cavity from communicating, thereby achieving the purpose of separating and controlling the fluid.
[0006] Furthermore, it also includes a sampling pipeline, which is fixedly connected to the valve seat body and has a sampling through hole.
[0007] Furthermore, the sampling through hole passes through the valve seat body, and the sampling through hole is communicated with the sampling port, so that the sampling through hole is communicated with the sampling chamber.
[0008] Furthermore, the valve seat body is provided with a connecting portion, and the connecting portion is provided with a preset number of threaded connecting holes.
[0009] Furthermore, the first communicating pipe is fixedly connected to the valve seat body by welding, screw / bolt connection, clamping, snap connection or integral molding.
[0010] Furthermore, the first communicating pipe 3 is fixedly connected to the valve seat body by welding, screw / bolt connection, clamping, snap connection or integral molding.
[0011] Furthermore, the sampling pipe is fixedly connected to the valve seat body by welding, screw / bolt connection, clamping, snap connection or integral molding.
[0012] The beneficial effects of the present application are as follows: the present application provides a two-way valve seat for chromatographic degradation, which has a simple structure and is easy to manufacture. In addition, since a first separation chamber and a second separation chamber are provided on the valve seat body, fluid separation control can be achieved; and a sampling through hole is provided on the valve seat body, so that the liquid flowing through the valve seat body can be sampled more simply during the chromatographic degradation process. BRIEF DESCRIPTION OF THE DRAWINGS
[0013] Figure 1 This is a structural schematic diagram of a two-way valve seat for chromatography degradation provided by the utility model.
[0014] Figure 2 This is another structural schematic diagram of a two-way valve seat for chromatography degradation provided by the utility model. DETAILED DESCRIPTION
[0015] The present application is further described in detail below by means of specific embodiments in conjunction with the accompanying drawings. Similar elements in different embodiments are numbered with associated similar elements. In the following embodiments, many detailed descriptions are provided to enable the present application to be better understood. However, those skilled in the art will readily appreciate that some of the features may be omitted in different circumstances, or may be replaced by other elements, materials, or methods. In some cases, some operations related to the present application are not shown or described in the specification. This is to avoid the core portion of the present application being overwhelmed by excessive descriptions. For those skilled in the art, it is not necessary to describe these related operations in detail. They can fully understand the related operations based on the description in the specification and the general technical knowledge in the art.
[0016] In addition, the features, operations, or characteristics described in the specification may be combined in any appropriate manner to form various implementations, and the operational steps involved in each embodiment may be interchanged or adjusted in a manner that is obvious to those skilled in the art. Therefore, the specification and drawings are only for the purpose of clearly describing a particular embodiment and do not imply a required composition and / or sequence.
[0017] The serial numbers assigned to components herein, such as "first," "second," etc., are used solely to distinguish the objects being described and do not convey any sequential or technical meaning. References to "connection" and "coupling" herein, unless otherwise specified, include both direct and indirect connections (couplings).
[0018] Please refer to Figure 1-2 The present application provides a two-way valve seat for chromatography degradation (hereinafter referred to as a two-way valve seat), the two-way valve seat comprising a valve seat body 1, a first connecting pipe 2, and a second connecting pipe 3. The valve seat body 1 is provided with a first separation cavity 11, a second separation cavity 12, and a partition 10. The partition 10 extends upward from the bottom of the first separation cavity 11 or the bottom of the second separation cavity 12 of the valve seat body 1 to a preset height, thereby separating the first separation cavity 11 from the second separation cavity 12, so that no fluid exchange occurs between the first separation cavity 11 and the second separation cavity 12; the second separation cavity 12 is provided with a first separation cavity 11, a second separation cavity 12, and a partition 10. A communicating pipe 2 and a second communicating pipe 3 are both fixedly connected to the valve seat body 1, the first communicating pipe 2 has a first fluid through hole 20, the second communicating pipe 3 has a second fluid through hole 30, the first fluid through hole 20 is connected to the first separation cavity 11, and the second fluid through hole 30 is connected to the second separation cavity 12; a sampling chamber 13 is also provided on the valve seat body 1, the sampling chamber 13 has a sampling port 14, the sampling chamber 13 runs through the valve seat body 1, and the sampling chamber 13 is connected to the first separation cavity 11 or the second separation cavity 12.
[0019] In one embodiment of the present application, the outer surface 100 of the partition 10 is flush with the plane where the outer contour 110 of the first separation cavity 11 and the plane where the outer contour 120 of the second separation cavity 12 are located, so that the partition 10 prevents the first separation cavity 11 and the second separation cavity 12 from communicating with each other, thereby achieving the purpose of separating and controlling the fluid.
[0020] In one embodiment of the present application, the two-way valve seat further includes a sampling pipe 4 , which is fixedly connected to the valve seat body 1 , and has a sampling through hole 40 .
[0021] In one embodiment of the present application, the sampling through hole 40 passes through the valve seat body 1 , and the sampling through hole 40 is in communication with the sampling port 14 , thereby enabling the sampling through hole 40 to communicate with the sampling chamber 13 .
[0022] In one embodiment of the present application, the valve seat body 1 is further provided with a connecting portion 15 , and the connecting portion 15 is provided with a preset number of threaded connecting holes 16 .
[0023] In one embodiment of the present application, the first connecting pipe 2 is fixedly connected to the valve seat body 1 by welding, screw / bolt connection, clamping, snap connection or integral molding.
[0024] In one embodiment of the present application, the first connecting pipe 3 is fixedly connected to the valve seat body 1 by welding, screw / bolt connection, clamping, snap connection or integral molding.
[0025] In one embodiment of the present application, the sampling pipe 4 is fixedly connected to the valve seat body 1 by welding, screw / bolt connection, clamping, snap connection or integral molding.
[0026] The working principle of the present application is as follows: the present application provides a two-way valve seat for chromatographic degradation, which includes a valve seat body, a first connecting pipe, and a second connecting pipe. The valve seat body is provided with a first separation inner cavity, a second separation inner cavity, and a partition. The partition extends upward from the bottom of the first separation inner cavity or the bottom of the second separation inner cavity of the valve seat body to a preset height, thereby separating the first separation inner cavity and the second separation inner cavity, so that no fluid exchange occurs between the first separation inner cavity and the second separation inner cavity; the first connecting pipe and the second connecting pipe are both fixedly connected to the valve seat body, the first connecting pipe has a first fluid through hole, and the second connecting pipe has a second fluid through hole, the first fluid through hole is connected to the first separation inner cavity, and the second fluid through hole is connected to the second separation cavity; a sampling chamber is also provided on the valve seat body, the sampling chamber has a sampling port, the sampling chamber runs through the valve seat body, and the sampling chamber is connected to the first separation inner cavity or the second separation cavity. During chromatographic degradation, one pipeline is connected to the first connecting pipeline, and the other pipeline is connected to the second connecting pipeline. This allows the fluid in one pipeline to flow into the first separation chamber through the first connecting pipeline, while the fluid in the other pipeline flows into the second separation chamber through the second connecting pipeline. The first and second separation chambers are separated by a partition, preventing fluid exchange, thereby achieving the purpose of separating and controlling the fluids. Furthermore, the liquid flowing into the valve seat body can be sampled through the sampling hole, thereby achieving the purpose of sampling during the chromatographic degradation process.
[0027] The present application provides a two-way valve seat for chromatographic degradation. The two-way valve seat has a simple structure and is easy to manufacture. In addition, since a first separation chamber and a second separation chamber are provided on the valve seat body, fluid separation control can be achieved. In addition, a sampling through hole is provided on the valve seat body, so that the liquid flowing through the valve seat body can be sampled more easily during the chromatographic degradation process.
[0028] The above embodiments are intended only to illustrate the technical concepts and features of the present invention. Their purpose is to enable those familiar with the art to understand the contents of the present invention and implement them accordingly. They are not intended to limit the scope of protection of the present invention. Any equivalent changes or modifications based on the spirit of the present invention are intended to be included in the scope of protection of the present invention.
Claims
1. A two-way valve seat for chromatography degradation, characterized in that:
18. The vent pipe of claim 17, wherein the valve seat body is provided with a first separation cavity, a second separation cavity, and a partition. The partition extends upward from the bottom of the first separation cavity or the bottom of the second separation cavity of the valve seat body to a preset height, thereby separating the first separation cavity and the second separation cavity, so that no fluid exchange occurs between the first separation cavity and the second separation cavity; the first communicating pipe and the second communicating pipe are both fixedly connected to the valve seat body, the first communicating pipe has a first fluid through hole, the second communicating pipe has a second fluid through hole, the first fluid through hole is connected to the first separation cavity, and the second fluid through hole is connected to the second separation cavity; a sampling chamber is also provided on the valve seat body, the sampling chamber has a sampling port, the sampling chamber passes through the valve seat body, and the sampling chamber is connected to the first separation cavity or the second separation cavity.
2. The two-way valve seat for chromatography degradation according to claim 1, characterized in that: The outer surface of the partition is flush with the plane where the outer contour of the first separation cavity and the plane where the outer contour of the second separation cavity are located, so that the partition prevents the first separation cavity and the second separation cavity from communicating, thereby achieving the purpose of separating and controlling the fluid.
3. The two-way valve seat for chromatography degradation according to claim 1, characterized in that: It also includes a sampling pipeline, which is fixedly connected to the valve seat body and has a sampling through hole.
4. The two-way valve seat for chromatography degradation according to claim 3, characterized in that: The sampling through hole passes through the valve seat body, and the sampling through hole is communicated with the sampling port, so that the sampling through hole is communicated with the sampling chamber.
5. The two-way valve seat for chromatography degradation according to claim 1, characterized in that: The valve seat body is further provided with a connecting portion, and the connecting portion is provided with a preset number of threaded connecting holes.
6. The two-way valve seat for chromatography degradation according to claim 1, characterized in that: The first communicating pipe is fixedly connected to the valve seat body by welding, screw / bolt connection, clamping, snap connection or integral molding.
7. The two-way valve seat for chromatography degradation according to claim 1, characterized in that: The first communicating pipe is fixedly connected to the valve seat body by welding, screw / bolt connection, clamping, snap connection or integral molding.
8. The two-way valve seat for chromatography degradation according to claim 3, characterized in that: The sampling pipe is fixedly connected to the valve seat body by welding, screw / bolt connection, clamping, snap connection or integral molding.